mRNA Editing: A to I Conversion

Sources:

#	Name	Source	Genes
1	mRNA Editing: A to I Conversion	Reactome	ADAR ADARB1
2	Formation of editosomes by ADAR proteins	Reactome	ADAR ADARB1
3	C6 deamination of adenosine	Reactome	ADAR ADARB1

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	ADAR	Adenosine Deaminase RNA Specific	Protein Coding	3
2	ADARB1	Adenosine Deaminase RNA Specific B1	Protein Coding	3

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Adar-related hereditary spastic paraplegia	Enrichment	ADAR	3.83
2	Dyschromatosis symmetrica hereditaria	Enrichment	ADAR	3.53
3	Aicardi-goutieres syndrome 6	Enrichment	ADAR	3.53
4	Neurodevelopmental disorder with hypotonia, microcephaly, and seizures	Enrichment	ADARB1	3.53
5	Symmetrical dyschromatosis of extremities	Enrichment	ADAR	3.53
6	Familial infantile bilateral striatal necrosis	Enrichment	ADAR	3.23
7	Aicardi-goutiares syndrome	Enrichment	ADAR	2.88
8	Aicardi-goutieres syndrome	Enrichment	ADAR	2.83
9	Colorectal cancer	Enrichment	ADAR	1.89

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Pathway Network for mRNA Editing: A to I Conversion