mRNA Splicing - Minor Pathway

No Pathway Network information available for mRNA Splicing - Minor Pathway

Pathways in the mRNA Splicing - Minor Pathway SuperPath

#	Name	Source	Genes
1	mRNA Splicing - Minor Pathway	Reactome	DDX23 DDX42 EFTUD2 GTF2F1 GTF2F2 NCBP1 NCBP2 PDCD7 POLR2A POLR2B POLR2C POLR2D POLR2E POLR2F POLR2G POLR2H POLR2I POLR2J POLR2K POLR2L PRPF6 PRPF8 RNPC3 SF3B1 SF3B2 SF3B3 SF3B4 SF3B5 SF3B6 SNRNP200 SNRNP25 SNRNP35 SNRNP40 SNRNP48 SNRPB SNRPD1 SNRPD2 SNRPD3 SNRPE SNRPF SNRPG SRSF1 SRSF2 SRSF6 SRSF7 TXNL4A YBX1 ZCRB1 ZMAT5 ZRSR2 (see all 50) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	PDCD7	Programmed Cell Death 7	Protein Coding	1
2	SF3B4	Splicing Factor 3b Subunit 4	Protein Coding	1
3	PRPF8	Pre-MRNA Processing Factor 8	Protein Coding	1
4	TXNL4A	Thioredoxin Like 4A	Protein Coding	1
5	SF3B2	Splicing Factor 3b Subunit 2	Protein Coding	1
6	SNRNP35	Small Nuclear Ribonucleoprotein U11/U12 Subunit 35	Protein Coding	1
7	DDX42	DEAD-Box Helicase 42	Protein Coding	1
8	SNRNP48	Small Nuclear Ribonucleoprotein U11/U12 Subunit 48	Protein Coding	1
9	NCBP2	Nuclear Cap Binding Protein Subunit 2	Protein Coding	1
10	SNRNP200	Small Nuclear Ribonucleoprotein U5 Subunit 200	Protein Coding	1
11	SF3B3	Splicing Factor 3b Subunit 3	Protein Coding	1
12	SF3B1	Splicing Factor 3b Subunit 1	Protein Coding	1
13	PRPF6	Pre-MRNA Processing Factor 6	Protein Coding	1
14	GTF2F1	General Transcription Factor IIF Subunit 1	Protein Coding	1
15	GTF2F2	General Transcription Factor IIF Subunit 2	Protein Coding	1
16	NCBP1	Nuclear Cap Binding Protein Subunit 1	Protein Coding	1
17	YBX1	Y-Box Binding Protein 1	Protein Coding	1
18	SF3B6	Splicing Factor 3b Subunit 6	Protein Coding	1
19	POLR2A	RNA Polymerase II Subunit A	Protein Coding	1
20	POLR2B	RNA Polymerase II Subunit B	Protein Coding	1
21	POLR2C	RNA Polymerase II Subunit C	Protein Coding	1
22	POLR2D	RNA Polymerase II Subunit D	Protein Coding	1
23	POLR2E	RNA Polymerase II, I And III Subunit E	Protein Coding	1
24	POLR2F	RNA Polymerase II, I And III Subunit F	Protein Coding	1
25	POLR2G	RNA Polymerase II Subunit G	Protein Coding	1
26	POLR2H	RNA Polymerase II, I And III Subunit H	Protein Coding	1
27	POLR2I	RNA Polymerase II Subunit I	Protein Coding	1
28	POLR2J	RNA Polymerase II Subunit J	Protein Coding	1
29	POLR2K	RNA Polymerase II, I And III Subunit K	Protein Coding	1
30	POLR2L	RNA Polymerase II, I And III Subunit L	Protein Coding	1
31	RNPC3	RNA Binding Region (RNP1, RRM) Containing 3	Protein Coding	1
32	ZMAT5	Zinc Finger Matrin-Type 5	Protein Coding	1
33	SRSF1	Serine And Arginine Rich Splicing Factor 1	Protein Coding	1
34	SRSF2	Serine And Arginine Rich Splicing Factor 2	Protein Coding	1
35	SRSF6	Serine And Arginine Rich Splicing Factor 6	Protein Coding	1
36	SRSF7	Serine And Arginine Rich Splicing Factor 7	Protein Coding	1
37	SNRPB	Small Nuclear Ribonucleoprotein Polypeptides B And B1	Protein Coding	1
38	SNRPD1	Small Nuclear Ribonucleoprotein D1 Polypeptide	Protein Coding	1
39	SNRPD2	Small Nuclear Ribonucleoprotein D2 Polypeptide	Protein Coding	1
40	SNRPD3	Small Nuclear Ribonucleoprotein D3 Polypeptide	Protein Coding	1
41	SNRPE	Small Nuclear Ribonucleoprotein Polypeptide E	Protein Coding	1
42	SNRPF	Small Nuclear Ribonucleoprotein Polypeptide F	Protein Coding	1
43	SNRPG	Small Nuclear Ribonucleoprotein Polypeptide G	Protein Coding	1
44	SNRNP25	Small Nuclear Ribonucleoprotein U11/U12 Subunit 25	Protein Coding	1
45	ZRSR2	Zinc Finger CCCH-Type, RNA Binding Motif And Serine/Arginine Rich 2	Protein Coding	1
46	SF3B5	Splicing Factor 3b Subunit 5	Protein Coding	1
47	ZCRB1	Zinc Finger CCHC-Type And RNA Binding Motif Containing 1	Protein Coding	1
48	EFTUD2	Elongation Factor Tu GTP Binding Domain Containing 2	Protein Coding	1
49	SNRNP40	Small Nuclear Ribonucleoprotein U5 Subunit 40	Protein Coding	1
50	DDX23	DEAD-Box Helicase 23	Protein Coding	1

Disorders associated with mRNA Splicing - Minor Pathway SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Esophageal atresia/tracheoesophageal fistula	Enrichment	EFTUD2, POLR2B	2.66
2	Acrofacial dysostosis syndrome of rodriguez	Enrichment	SF3B4	2.43
3	Orofaciodigital syndrome xxi	Enrichment	ZRSR2	2.43
4	Retinitis pigmentosa 33	Enrichment	SNRNP200	2.43
5	Mandibulofacial dysostosis, guion-almeida type	Enrichment	EFTUD2	2.43
6	Retinitis pigmentosa 60	Enrichment	PRPF6	2.43
7	Pituitary hormone deficiency, combined or isolated, 7	Enrichment	RNPC3	2.43
8	Combined or isolated pituitary growth hormone deficiency 7	Enrichment	RNPC3	2.43
9	Genetic syndromic pierre robin syndrome	Enrichment	EFTUD2	2.43
10	Cerebrocostomandibular syndrome	Enrichment	SNRPB	2.13
11	Acrofacial dysostosis 1, nager type	Enrichment	SF3B4	2.13
12	Retinitis pigmentosa 13	Enrichment	PRPF8	2.13
13	Waardenburg syndrome, type 4c	Enrichment	POLR2F	2.13
14	Hypotrichosis 11	Enrichment	SNRPE	2.13
15	Neurodevelopmental disorder with dysmorphic facies and behavioral abnormalities	Enrichment	SRSF1	2.13
16	Peripheral demyelinating neuropathy, central dysmyelination, waardenburg syndrome, and hirschsprung disease	Enrichment	POLR2F	2.13
17	Leukemia, acute myeloid	Enrichment	SF3B1, SRSF2	2.02
18	Waardenburg syndrome, type 2a	Enrichment	POLR2F	1.96
19	Burn-mckeown syndrome	Enrichment	TXNL4A	1.96
20	Myelodysplastic syndrome with ring sideroblasts	Enrichment	SF3B1	1.96
21	Neurodevelopmental disorder with hypotonia and variable intellectual and behavioral abnormalities	Enrichment	POLR2A	1.83
22	Chronic myelogenous leukemia, bcr-abl1 positive	Enrichment	SF3B1	1.83
23	Chronic myelomonocytic leukemia	Enrichment	SRSF2	1.83
24	Systemic mastocytosis with associated hematologic neoplasm	Enrichment	SRSF2	1.83
25	Hypogonadotropic hypogonadism 1 with or without anosmia	Enrichment	POLR2F	1.74
26	Holoprosencephaly	Enrichment	ZRSR2	1.74
27	Aggressive systemic mastocytosis	Enrichment	SRSF2	1.74
28	Craniofacial microsomia 1	Enrichment	SF3B2	1.66
29	Melanoma, uveal	Enrichment	SF3B1	1.66
30	Pierre robin syndrome	Enrichment	SNRPB	1.66
31	Holoprosencephaly 1	Enrichment	ZRSR2	1.66
32	Waardenburg syndrome, type 4a	Enrichment	POLR2F	1.66
33	Waardenburg syndrome	Enrichment	POLR2F	1.66
34	Treacher collins syndrome 1	Enrichment	EFTUD2	1.59
35	Waardenburg syndrome, type 1	Enrichment	POLR2F	1.59
36	Polymicrogyria, bilateral perisylvian, x-linked	Enrichment	DDX23	1.59
37	Waardenburg syndrome, type 2e	Enrichment	POLR2F	1.59
38	Leukemia, chronic myeloid	Enrichment	SF3B1	1.59
39	Isolated growth hormone deficiency, type ia	Enrichment	RNPC3	1.54
40	Tracheoesophageal fistula with or without esophageal atresia	Enrichment	EFTUD2	1.49
41	Atypical chronic myeloid leukemia, bcr-abl1 negative	Enrichment	SRSF2	1.49
42	Bilateral perisylvian polymicrogyria	Enrichment	DDX23	1.49
43	Hypotrichosis simplex	Enrichment	SNRPE	1.49
44	Isolated tracheo-esophageal fistula	Enrichment	EFTUD2	1.44
45	Myelodysplastic syndrome	Enrichment	SF3B1	1.40
46	Retinitis pigmentosa	Enrichment	PRPF6, PRPF8, SNRNP200	1.37
47	Kallmann syndrome	Enrichment	POLR2F	1.09
48	Hereditary retinal dystrophy	Enrichment	PRPF6, PRPF8, SNRNP200	1.04
49	Fundus dystrophy	Enrichment	PRPF6, PRPF8, SNRNP200	1.04
50	Hirschsprung disease 1	Enrichment	POLR2F	0.99
51	Rare genetic deafness	Enrichment	POLR2F	0.60
52	Complex neurodevelopmental disorder	Enrichment	PRPF8	0.43

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

mRNA Splicing - Minor Pathway

Pathway Network for mRNA Splicing - Minor Pathway

Member Pathways for mRNA Splicing - Minor Pathway

Pathways in the mRNA Splicing - Minor Pathway SuperPath

Associated Genes for mRNA Splicing - Minor Pathway

Associated Disorders for mRNA Splicing - Minor Pathway

Disorders associated with mRNA Splicing - Minor Pathway SuperPath

STRING Interaction Network for mRNA Splicing - Minor Pathway

Sources for mRNA Splicing - Minor Pathway