MSP-RON Signaling

No Pathway Network information available for MSP-RON Signaling

Pathways in the MSP-RON Signaling SuperPath

#	Name	Source	Genes
1	MSP-RON Signaling	QIAGEN	ACTA1 ACTA2 ACTB ACTG1 ACTG2 CCL2 CCR2 CSF1 CSF2RB F11 F12 IFNG IL12A IL12B IL18 IL1B IL3RA ITGAM ITGB2 JAK2 KLK1 KLK10 KLK11 KLK12 KLK13 KLK14 KLK15 KLK2 KLK3 KLK4 KLK5 KLK6 KLK7 KLK8 KLK9 KLKB1 MST1 MST1R NOS2 PIK3R1 PIK3R2 PIK3R3 PIK3R4 PIK3R5 PRKCZ TLR2 TLR4 TNF (see all 48) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	ACTA1	Actin Alpha 1, Skeletal Muscle	Protein Coding	1
2	ACTA2	Actin Alpha 2, Smooth Muscle	Protein Coding	1
3	ACTB	Actin Beta	Protein Coding	1
4	ACTG1	Actin Gamma 1	Protein Coding	1
5	ACTG2	Actin Gamma 2, Smooth Muscle	Protein Coding	1
6	CCL2	C-C Motif Chemokine Ligand 2	Protein Coding	1
7	CCR2	C-C Motif Chemokine Receptor 2	Protein Coding	1
8	CSF1	Colony Stimulating Factor 1	Protein Coding	1
9	CSF2RB	Colony Stimulating Factor 2 Receptor Subunit Beta	Protein Coding	1
10	F11	Coagulation Factor XI	Protein Coding	1
11	F12	Coagulation Factor XII	Protein Coding	1
12	IFNG	Interferon Gamma	Protein Coding	1
13	IL12A	Interleukin 12A	Protein Coding	1
14	IL12B	Interleukin 12B	Protein Coding	1
15	IL18	Interleukin 18	Protein Coding	1
16	IL1B	Interleukin 1 Beta	Protein Coding	1
17	IL3RA	Interleukin 3 Receptor Subunit Alpha	Protein Coding	1
18	ITGAM	Integrin Subunit Alpha M	Protein Coding	1
19	ITGB2	Integrin Subunit Beta 2	Protein Coding	1
20	JAK2	Janus Kinase 2	Protein Coding	1
21	KLK1	Kallikrein 1	Protein Coding	1
22	KLK10	Kallikrein Related Peptidase 10	Protein Coding	1
23	KLK11	Kallikrein Related Peptidase 11	Protein Coding	1
24	KLK12	Kallikrein Related Peptidase 12	Protein Coding	1
25	KLK13	Kallikrein Related Peptidase 13	Protein Coding	1
26	KLK14	Kallikrein Related Peptidase 14	Protein Coding	1
27	KLK15	Kallikrein Related Peptidase 15	Protein Coding	1
28	KLK2	Kallikrein Related Peptidase 2	Protein Coding	1
29	KLK3	Kallikrein Related Peptidase 3	Protein Coding	1
30	KLK4	Kallikrein Related Peptidase 4	Protein Coding	1
31	KLK5	Kallikrein Related Peptidase 5	Protein Coding	1
32	KLK6	Kallikrein Related Peptidase 6	Protein Coding	1
33	KLK7	Kallikrein Related Peptidase 7	Protein Coding	1
34	KLK8	Kallikrein Related Peptidase 8	Protein Coding	1
35	KLK9	Kallikrein Related Peptidase 9	Protein Coding	1
36	KLKB1	Kallikrein B1	Protein Coding	1
37	MST1	Macrophage Stimulating 1	Protein Coding	1
38	MST1R	Macrophage Stimulating 1 Receptor	Protein Coding	1
39	NOS2	Nitric Oxide Synthase 2	Protein Coding	1
40	PIK3R5	Phosphoinositide-3-Kinase Regulatory Subunit 5	Protein Coding	1
41	PIK3R1	Phosphoinositide-3-Kinase Regulatory Subunit 1	Protein Coding	1
42	PIK3R2	Phosphoinositide-3-Kinase Regulatory Subunit 2	Protein Coding	1
43	PIK3R3	Phosphoinositide-3-Kinase Regulatory Subunit 3	Protein Coding	1
44	PIK3R4	Phosphoinositide-3-Kinase Regulatory Subunit 4	Protein Coding	1
45	PRKCZ	Protein Kinase C Zeta	Protein Coding	1
46	TLR2	Toll Like Receptor 2	Protein Coding	1
47	TLR4	Toll Like Receptor 4	Protein Coding	1
48	TNF	Tumor Necrosis Factor	Protein Coding	1

Disorders associated with MSP-RON Signaling SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Baraitser-winter cerebrofrontofacial syndrome	Enrichment	ACTB, ACTG1	4.91
2	Human immunodeficiency virus type 1	Enrichment	CCL2, CCR2, IFNG	4.49
3	Behcet syndrome	Enrichment	IL12A, TLR4	2.70
4	Malaria	Enrichment	NOS2, TNF	2.53
5	Leprosy 3	Enrichment	TLR2	2.45
6	Baraitser-winter syndrome 1	Enrichment	ACTB	2.45
7	Systemic lupus erythematosus 6	Enrichment	ITGAM	2.45
8	Angioedema, hereditary, 3	Enrichment	F12	2.45
9	Prekallikrein deficiency	Enrichment	KLKB1	2.45
10	Congenital myopathy 2a, typical, autosomal dominant	Enrichment	ACTA1	2.45
11	Polycystic lung disease	Enrichment	CCR2	2.45
12	Amelogenesis imperfecta, hypomaturation type, iia1	Enrichment	KLK4	2.45
13	Myopathy, scapulohumeroperoneal	Enrichment	ACTA1	2.45
14	Ataxia-oculomotor apraxia 3	Enrichment	PIK3R5	2.45
15	Megacystis-microcolon-intestinal hypoperistalsis syndrome 5	Enrichment	ACTG2	2.45
16	Immunodeficiency 69	Enrichment	IFNG	2.45
17	Short syndrome	Enrichment	PIK3R1	2.45
18	Congenital smooth muscle hamartoma, with or without hemihypertrophy	Enrichment	ACTB	2.45
19	Becker nevus syndrome	Enrichment	ACTB	2.45
20	Dystonia-deafness syndrome 1	Enrichment	ACTB	2.45
21	Visceral neuropathy, familial, 3, autosomal dominant	Enrichment	ACTG2	2.45
22	Surfactant metabolism dysfunction, pulmonary, 5	Enrichment	CSF2RB	2.45
23	Congenital myopathy 2b, severe infantile, autosomal recessive	Enrichment	ACTA1	2.45
24	Immunodeficiency 36 with lymphoproliferation	Enrichment	PIK3R1	2.45
25	Immunodeficiency 29	Enrichment	IL12B	2.45
26	Nasopharyngeal carcinoma 3	Enrichment	MST1R	2.45
27	Autosomal dominant familial visceral neuropathy	Enrichment	ACTG2	2.45
28	Agammaglobulinemia 7, autosomal recessive	Enrichment	PIK3R1	2.45
29	Macular degeneration, age-related, 10	Enrichment	TLR4	2.45
30	Congenital myopathy 2c, severe infantile, autosomal dominant	Enrichment	ACTA1	2.45
31	Thrombocytopenia 8, with dysmorphic features and developmental delay	Enrichment	ACTB	2.45
32	Baraitser-winter syndrome	Enrichment	ACTB	2.45
33	Ichthyosis with erythrokeratoderma	Enrichment	KLK11	2.45
34	Amelogenesis imperfecta type 2a1	Enrichment	KLK4	2.45
35	Zebra body myopathy	Enrichment	ACTA1	2.45
36	Congenital smooth muscle hamartoma	Enrichment	ACTB	2.45
37	Urticaria	Enrichment	F12	2.45
38	Developmental malformations-deafness-dystonia syndrome	Enrichment	ACTB	2.45
39	Actin-accumulation myopathy	Enrichment	ACTA1	2.45
40	Myopathic intestinal pseudoobstruction	Enrichment	ACTG2	2.45
41	F12-associated cold autoinflammatory syndrome	Enrichment	F12	2.45
42	Inherited prekallikrein deficiency	Enrichment	KLKB1	2.45
43	Actg2 visceral myopathy	Enrichment	ACTG2	2.45
44	Leukocyte adhesion deficiency, type i	Enrichment	ITGB2	2.15
45	Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy 2	Enrichment	PIK3R5	2.15
46	Aortic aneurysm, familial thoracic 2	Enrichment	ACTA2	2.15
47	Deafness, autosomal dominant 20	Enrichment	ACTG1	2.15
48	Smooth muscle dysfunction syndrome	Enrichment	ACTA2	2.15
49	Leukocyte adhesion deficiency, type iii	Enrichment	ITGB2	2.15
50	Aortic aneurysm, familial thoracic 6	Enrichment	ACTA2	2.15
51	Kallikrein, decreased urinary activity of	Enrichment	KLK1	2.15
52	Baraitser-winter syndrome 2	Enrichment	ACTG1	2.15
53	Factor xii deficiency	Enrichment	F12	2.15
54	Moyamoya disease 5	Enrichment	ACTA2	2.15
55	Thrombocythemia 3	Enrichment	JAK2	2.15
56	Immunodeficiency 127	Enrichment	TNF	2.15
57	Factor xi deficiency	Enrichment	F11	2.15
58	Hereditary angioedema	Enrichment	F12	2.15
59	Polycythemia	Enrichment	JAK2	2.15
60	Hypereosinophilic syndrome	Enrichment	JAK2	2.15
61	Angioedema	Enrichment	F12	2.15
62	Intestinal obstruction	Enrichment	ACTG2	2.15
63	Systemic lupus erythematosus	Enrichment	ITGAM, TNF	2.08
64	Angioedema, hereditary, 1	Enrichment	F12	1.98
65	Factor x deficiency	Enrichment	F11	1.98
66	Takayasu arteritis	Enrichment	IL12B	1.98
67	Polycythemia vera	Enrichment	JAK2	1.98
68	Tuberous sclerosis 1	Enrichment	IFNG	1.98
69	Psoriatic arthritis	Enrichment	TNF	1.98
70	Hepatitis c virus	Enrichment	IFNG	1.98
71	Congenital lipomatous overgrowth, vascular malformations, and epidermal nevi	Enrichment	PIK3R1	1.98
72	Tuberous sclerosis 2	Enrichment	IFNG	1.98
73	Immunodeficiency 14a with lymphoproliferation, autosomal dominant	Enrichment	PIK3R1	1.98
74	Breast implant-associated anaplastic large cell lymphoma	Enrichment	JAK2	1.98
75	Immunodeficiency 14	Enrichment	PIK3R1	1.98
76	Migraine without aura	Enrichment	TNF	1.98
77	Congenital factor x deficiency	Enrichment	F11	1.98
78	Erythrocytosis, familial, 1	Enrichment	JAK2	1.85
79	Nemaline myopathy 2	Enrichment	ACTA1	1.85
80	Megacystis-microcolon-intestinal hypoperistalsis syndrome 1	Enrichment	ACTG2	1.85
81	Autoimmune lymphoproliferative syndrome	Enrichment	ACTA2	1.85
82	Budd-chiari syndrome	Enrichment	JAK2	1.85
83	Megalencephaly-capillary malformation-polymicrogyria syndrome	Enrichment	PIK3R2	1.85
84	Megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome 1	Enrichment	PIK3R2	1.85
85	Aminoacylase 1 deficiency	Enrichment	ACTB	1.85
86	Cerebral malaria	Enrichment	TNF	1.85
87	Intermediate nemaline myopathy	Enrichment	ACTA1	1.85
88	Pseudomyogenic hemangioendothelioma	Enrichment	ACTB	1.85
89	Myeloma, multiple	Enrichment	MST1R, PIK3R2	1.78
90	Visceral myopathy 1	Enrichment	ACTG2	1.76
91	Congenital myopathy 3 with rigid spine	Enrichment	ACTA1	1.76
92	Cholangitis, primary sclerosing	Enrichment	MST1	1.76
93	Myeloproliferative neoplasm	Enrichment	JAK2	1.76
94	Vascular dementia	Enrichment	TNF	1.76
95	Coloboma of choroid and retina	Enrichment	ACTG1	1.76
96	Hereditary pulmonary alveolar proteinosis	Enrichment	CSF2RB	1.76
97	Severe congenital nemaline myopathy	Enrichment	ACTA1	1.76
98	Idiopathic aplastic anemia	Enrichment	IFNG	1.76
99	Moyamoya disease 1	Enrichment	ACTA2	1.68
100	Intestinal pseudo-obstruction	Enrichment	ACTG2	1.68
101	Typical nemaline myopathy	Enrichment	ACTA1	1.68
102	Myelofibrosis	Enrichment	JAK2	1.61
103	Essential thrombocythemia	Enrichment	JAK2	1.61
104	Childhood-onset nemaline myopathy	Enrichment	ACTA1	1.61
105	Amelogenesis imperfecta type 2	Enrichment	KLK4	1.61
106	Overgrowth syndrome	Enrichment	PIK3R1	1.61
107	Leukemia, acute lymphoblastic 3	Enrichment	JAK2	1.50
108	Primary biliary cholangitis	Enrichment	IL12A	1.50
109	Cat eye syndrome	Enrichment	ACTG1	1.46
110	Aplastic anemia	Enrichment	IFNG	1.46
111	Nemaline myopathy	Enrichment	ACTA1	1.46
112	Autosomal non-syndromic agammaglobulinemia	Enrichment	PIK3R1	1.46
113	Colorectal cancer	Enrichment	PIK3R1, TLR2	1.42
114	Asthma	Enrichment	TNF	1.42
115	Bilirubin metabolic disorder	Enrichment	F12	1.42
116	Alzheimer's disease	Enrichment	TNF	1.35
117	Chromosome 1p36 deletion syndrome	Enrichment	PRKCZ	1.35
118	Amelogenesis imperfecta	Enrichment	KLK4	1.35
119	Lung cancer susceptibility 3	Enrichment	ACTA2	1.31
120	Congenital myopathy 4a, autosomal dominant	Enrichment	ACTA1	1.29
121	Hypertension	Enrichment	F12	1.26
122	Neuromuscular disease	Enrichment	ACTA1	1.21
123	Congenital myopathy	Enrichment	ACTA1	1.19
124	Microcephaly	Enrichment	ACTB, ACTG1	1.15
125	Lissencephaly	Enrichment	ACTG1	1.14
126	Centronuclear myopathy	Enrichment	ACTA1	1.14
127	Hydrops fetalis, nonimmune	Enrichment	ACTA1	1.05
128	Non-immune hydrops fetalis	Enrichment	ACTA1	0.98
129	Lung cancer	Enrichment	ACTA2	0.97
130	Connective tissue disease	Enrichment	ACTA2	0.97
131	Cakut	Enrichment	ACTG1	0.94
132	Non-syndromic genetic deafness	Enrichment	ACTG1	0.92
133	Fetal akinesia deformation sequence 1	Enrichment	ACTA1	0.91
134	Leukemia, acute myeloid	Enrichment	JAK2	0.88
135	Myopathy	Enrichment	ACTA1	0.88
136	Distal arthrogryposis	Enrichment	ACTA1	0.86
137	Nonsyndromic hearing loss	Enrichment	ACTG1	0.86
138	Gastric cancer	Enrichment	IL1B	0.85
139	Familial thoracic aortic aneurysm and aortic dissection	Enrichment	ACTA2	0.84
140	Thrombocytopenia	Enrichment	F11	0.80
141	Rare autosomal dominant non-syndromic sensorineural deafness type dfna	Enrichment	ACTG1	0.77
142	Primary ovarian insufficiency	Enrichment	JAK2	0.72
143	Rare genetic deafness	Enrichment	ACTG1	0.61
144	Dilated cardiomyopathy	Enrichment	ACTA1	0.61

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

MSP-RON Signaling

Pathway Network for MSP-RON Signaling

Member Pathways for MSP-RON Signaling

Pathways in the MSP-RON Signaling SuperPath

Associated Genes for MSP-RON Signaling

Associated Disorders for MSP-RON Signaling

Disorders associated with MSP-RON Signaling SuperPath

STRING Interaction Network for MSP-RON Signaling

Sources for MSP-RON Signaling