Myogenesis

No Pathway Network information available for Myogenesis

Pathways in the Myogenesis SuperPath

#	Name	Source	Genes
1	Myogenesis	Reactome	ABL1 BNIP2 BOC BORCS8-MEF2B CDC42 CDH15 CDH2 CDH4 CDON CTNNA1 CTNNA2 CTNNB1 MAP2K6 MAPK11 MAPK12 MAPK14 MEF2A MEF2B MEF2C MEF2D MYF5 MYF6 MYOD1 MYOG NEO1 NTN3 SPAG9 TCF12 TCF3 TCF4 (see all 30) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	CDH2	Cadherin 2	Protein Coding	1
2	CDH4	Cadherin 4	Protein Coding	1
3	MEF2B	Myocyte Enhancer Factor 2B	Protein Coding	1
4	CDH15	Cadherin 15	Protein Coding	1
5	MAPK14	Mitogen-Activated Protein Kinase 14	Protein Coding	1
6	CTNNA1	Catenin Alpha 1	Protein Coding	1
7	CTNNA2	Catenin Alpha 2	Protein Coding	1
8	CTNNB1	Catenin Beta 1	Protein Coding	1
9	ABL1	ABL Proto-Oncogene 1, Non-Receptor Tyrosine Kinase	Protein Coding	1
10	MEF2A	Myocyte Enhancer Factor 2A	Protein Coding	1
11	BORCS8-MEF2B	BORCS8-MEF2B Readthrough	Protein Coding	1
12	MEF2C	Myocyte Enhancer Factor 2C	Protein Coding	1
13	MEF2D	Myocyte Enhancer Factor 2D	Protein Coding	1
14	MYF5	Myogenic Factor 5	Protein Coding	1
15	MYF6	Myogenic Factor 6	Protein Coding	1
16	MYOD1	Myogenic Differentiation 1	Protein Coding	1
17	MYOG	Myogenin	Protein Coding	1
18	NEO1	Neogenin 1	Protein Coding	1
19	NTN3	Netrin 3	Protein Coding	1
20	CDON	Cell Adhesion Associated, Oncogene Regulated	Protein Coding	1
21	MAPK11	Mitogen-Activated Protein Kinase 11	Protein Coding	1
22	MAP2K6	Mitogen-Activated Protein Kinase Kinase 6	Protein Coding	1
23	MAPK12	Mitogen-Activated Protein Kinase 12	Protein Coding	1
24	BNIP2	BCL2 Interacting Protein 2	Protein Coding	1
25	TCF4	Transcription Factor 4	Protein Coding	1
26	TCF3	Transcription Factor 3	Protein Coding	1
27	TCF12	Transcription Factor 12	Protein Coding	1
28	SPAG9	Sperm Associated Antigen 9	Protein Coding	1
29	BOC	BOC Cell Adhesion Associated, Oncogene Regulated	Protein Coding	1
30	CDC42	Cell Division Cycle 42	Protein Coding	1

Disorders associated with Myogenesis SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Myopathy, centronuclear, 1	Enrichment	MYF6, MYOD1	4.15
2	Craniosynostosis	Enrichment	CTNNA1, TCF12	3.06
3	Autism spectrum disorder	Enrichment	MEF2C, TCF12, TCF4	2.76
4	Macular dystrophy, patterned, 2	Enrichment	CTNNA1	2.66
5	Intellectual developmental disorder, autosomal dominant 3	Enrichment	CDH15	2.66
6	Agammaglobulinemia 8b, autosomal recessive	Enrichment	TCF3	2.66
7	Cortical dysplasia, complex, with other brain malformations 9	Enrichment	CTNNA2	2.66
8	Agenesis of corpus callosum, cardiac, ocular, and genital syndrome	Enrichment	CDH2	2.66
9	Neurodevelopmental disorder with hypotonia, stereotypic hand movements, and impaired language	Enrichment	MEF2C	2.66
10	Agammaglobulinemia 8a, autosomal dominant	Enrichment	TCF3	2.66
11	Coronary artery disease, autosomal dominant, 1	Enrichment	MEF2A	2.66
12	Ophthalmoplegia, external, with rib and vertebral anomalies	Enrichment	MYF5	2.66
13	Arrhythmogenic right ventricular dysplasia, familial, 14	Enrichment	CDH2	2.66
14	Holoprosencephaly 11	Enrichment	CDON	2.66
15	Craniosynostosis 3	Enrichment	TCF12	2.66
16	Congenital myopathy 17	Enrichment	MYOD1	2.66
17	Corneal dystrophy, fuchs endothelial, 3	Enrichment	TCF4	2.66
18	Takenouchi-kosaki syndrome	Enrichment	CDC42	2.66
19	Attention deficit-hyperactivity disorder 8	Enrichment	CDH2	2.66
20	Adenoid ameloblastoma	Enrichment	CTNNB1	2.66
21	5q14.3 microdeletion syndrome	Enrichment	MEF2C	2.66
22	Complete atrioventricular septal defect without ventricular hypoplasia	Enrichment	MEF2C	2.66
23	Nocarh syndrome	Enrichment	CDC42	2.66
24	Hypogonadotropic hypogonadism 26 with or without anosmia	Enrichment	TCF12	2.66
25	Mef2c-related disorder	Enrichment	MEF2C	2.66
26	Microcystic stromal tumor	Enrichment	CTNNB1	2.66
27	Microcephaly	Enrichment	ABL1, CTNNB1, TCF4	2.61
28	Osteopathia striata with cranial sclerosis	Enrichment	CTNNB1	2.35
29	Congenital heart defects and skeletal malformations syndrome	Enrichment	ABL1	2.35
30	Neurodegeneration, infantile-onset, with optic atrophy and brain abnormalities	Enrichment	BORCS8-MEF2B	2.35
31	Childhood hepatocellular carcinoma	Enrichment	CTNNB1	2.35
32	Immune system disease	Enrichment	CDC42	2.35
33	Juvenile nasopharyngeal angiofibroma	Enrichment	CTNNB1	2.35
34	B-lymphoblastic leukemia/lymphoma with t(1;19)(q23;p13.3)	Enrichment	TCF3	2.35
35	Teratoma	Enrichment	CTNNB1	2.35
36	B-lymphoblastic leukemia/lymphoma with t(17;19)	Enrichment	TCF3	2.35
37	Autosomal dominant non-syndromic intellectual disability	Enrichment	CDH15, TCF4	2.27
38	Hereditary breast ovarian cancer syndrome	Enrichment	CTNNA1, CTNNA2	2.19
39	Desmoid disease, hereditary	Enrichment	CTNNB1	2.18
40	Neurodevelopmental disorder with spastic diplegia and visual defects	Enrichment	CTNNB1	2.18
41	Anus, imperforate	Enrichment	CTNNB1	2.18
42	Exudative vitreoretinopathy 7	Enrichment	CTNNB1	2.18
43	Desmoid tumor	Enrichment	CTNNB1	2.18
44	T-cell acute lymphoblastic leukemia	Enrichment	ABL1	2.18
45	Butterfly-shaped pigment dystrophy	Enrichment	CTNNA1	2.18
46	Diffuse gastric and lobular breast cancer syndrome	Enrichment	CTNNA1	2.05
47	Polyposis syndrome, hereditary mixed, 1	Enrichment	CTNNA1	2.05
48	Pitt-hopkins syndrome	Enrichment	TCF4	2.05
49	Pilomatrixoma	Enrichment	CTNNB1	2.05
50	Alazami syndrome	Enrichment	CTNNB1	2.05
51	Chronic myelogenous leukemia, bcr-abl1 positive	Enrichment	ABL1	2.05
52	Craniopharyngioma	Enrichment	CTNNB1	2.05
53	Noonan syndrome-like disorder with or without juvenile myelomonocytic leukemia	Enrichment	CDC42	2.05
54	Non-syndromic bicoronal craniosynostosis	Enrichment	TCF12	2.05
55	Exudative vitreoretinopathy 1	Enrichment	CTNNB1	1.96
56	Chondrosarcoma, extraskeletal myxoid	Enrichment	TCF12	1.96
57	Cholangitis, primary sclerosing	Enrichment	TCF4	1.96
58	Fuchs' endothelial dystrophy	Enrichment	TCF4	1.96
59	Weyers acrofacial dysostosis	Enrichment	CTNNB1	1.88
60	Adrenocortical carcinoma	Enrichment	CTNNB1	1.88
61	Leukemia, chronic myeloid	Enrichment	ABL1	1.81
62	Gallbladder cancer	Enrichment	CTNNB1	1.81
63	Moyamoya angiopathy	Enrichment	ABL1	1.81
64	B-lymphoblastic leukemia/lymphoma with t(9;22)(q34.1;q11.2)	Enrichment	ABL1	1.81
65	Colorectal cancer	Enrichment	CTNNA1, CTNNB1	1.80
66	Spastic paraplegia 4, autosomal dominant	Enrichment	TCF4	1.76
67	Exudative vitreoretinopathy	Enrichment	CTNNB1	1.76
68	Adult hepatocellular carcinoma	Enrichment	CTNNB1	1.70
69	Autosomal non-syndromic agammaglobulinemia	Enrichment	TCF3	1.66
70	Epicanthus	Enrichment	TCF4	1.58
71	Lip and oral cavity carcinoma	Enrichment	ABL1	1.58
72	Microphthalmia/coloboma 12	Enrichment	CDON	1.55
73	Stereotypic movement disorder	Enrichment	TCF4	1.55
74	Medulloblastoma	Enrichment	CTNNB1	1.52
75	Heart disease	Enrichment	ABL1	1.52
76	Inherited isolated arrhythmogenic cardiomyopathy, dominant-right variant	Enrichment	CDH2	1.52
77	Pituitary stalk interruption syndrome	Enrichment	CDON	1.52
78	Coloboma of macula	Enrichment	CDON	1.49
79	Corpus callosum, agenesis of	Enrichment	CDH2	1.49
80	Isolated corpus callosum agenesis	Enrichment	CDH2	1.49
81	Septopreoptic holoprosencephaly	Enrichment	CDON	1.49
82	Intellectual disability-hypoplastic corpus callosum-preauricular tag syndrome	Enrichment	CDH2	1.49
83	Midline interhemispheric variant of holoprosencephaly	Enrichment	CDON	1.49
84	Microform holoprosencephaly	Enrichment	CDON	1.46
85	Lobar holoprosencephaly	Enrichment	CDON	1.46
86	Polycystic liver disease	Enrichment	CTNNB1	1.43
87	Autosomal dominant polycystic liver disease	Enrichment	CTNNB1	1.43
88	Alobar holoprosencephaly	Enrichment	CDON	1.43
89	Semilobar holoprosencephaly	Enrichment	CDON	1.41
90	Arteriovenous malformations of the brain	Enrichment	CDH2	1.38
91	Hepatoblastoma	Enrichment	CTNNB1	1.34
92	Hepatocellular carcinoma	Enrichment	CTNNB1	1.32
93	Precursor t-cell acute lymphoblastic leukemia	Enrichment	ABL1	1.30
94	Scoliosis	Enrichment	MYF5	1.29
95	Auditory neuropathy	Enrichment	CDH2	1.25
96	Bladder cancer	Enrichment	CTNNB1	1.21
97	Fetal akinesia deformation sequence 1	Enrichment	MYOD1	1.10
98	Distal arthrogryposis	Enrichment	MYOD1	1.05
99	Myeloma, multiple	Enrichment	TCF3	0.93
100	Frontotemporal dementia and/or amyotrophic lateral sclerosis 7	Enrichment	MEF2C	0.92
101	Ovarian cancer	Enrichment	CTNNB1	0.70
102	Congenital nervous system abnormality	Enrichment	CTNNB1	0.68
103	Nervous system disease	Enrichment	CTNNB1	0.68
104	Inherited cancer-predisposing syndrome	Enrichment	CTNNA1	0.59
105	Hereditary retinal dystrophy	Enrichment	CTNNA1	0.32
106	Fundus dystrophy	Enrichment	CTNNA1	0.32

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Pathway Network for Myogenesis

Member Pathways for Myogenesis

Pathways in the Myogenesis SuperPath

Associated Genes for Myogenesis

Associated Disorders for Myogenesis

Disorders associated with Myogenesis SuperPath

STRING Interaction Network for Myogenesis

Sources for Myogenesis