NAD metabolism, sirtuins and aging

No Pathway Network information available for NAD metabolism, sirtuins and aging

#	Name	Source	Genes
1	NAD metabolism, sirtuins and aging	WikiPathways	FOXO1 FOXO3 HIF1A NAMPT NFKB1 PARP1 PPARG ROS1 SIRT1 SIRT3 TFAM (see all 11) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	TFAM	Transcription Factor A, Mitochondrial	Protein Coding	1
2	ROS1	ROS Proto-Oncogene 1, Receptor Tyrosine Kinase	Protein Coding	1
3	PPARG	Peroxisome Proliferator Activated Receptor Gamma	Protein Coding	1
4	NFKB1	Nuclear Factor Kappa B Subunit 1	Protein Coding	1
5	HIF1A	Hypoxia Inducible Factor 1 Subunit Alpha	Protein Coding	1
6	SIRT1	Sirtuin 1	Protein Coding	1
7	SIRT3	Sirtuin 3	Protein Coding	1
8	FOXO3	Forkhead Box O3	Protein Coding	1
9	FOXO1	Forkhead Box O1	Protein Coding	1
10	PARP1	Poly(ADP-Ribose) Polymerase 1	Protein Coding	1
11	NAMPT	Nicotinamide Phosphoribosyltransferase	Protein Coding	1

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Giant cell glioblastoma	Enrichment	PPARG, ROS1	4.09
2	Pparg-associated congenital generalized lipodystrophy	Enrichment	PPARG	3.09
3	Carotid intimal medial thickness 1	Enrichment	PPARG	2.79
4	Immunodeficiency, common variable, 12, with autoimmunity	Enrichment	NFKB1	2.79
5	Mitochondrial dna depletion syndrome 15	Enrichment	TFAM	2.79
6	Familial partial lipodystrophy	Enrichment	PPARG	2.79
7	Common variable immunodeficiency 12	Enrichment	NFKB1	2.79
8	Enchondromatosis	Enrichment	HIF1A	2.61
9	Lipodystrophy, familial partial, type 3	Enrichment	PPARG	2.49
10	Cholangiocarcinoma	Enrichment	ROS1	2.49
11	Leptin deficiency or dysfunction	Enrichment	PPARG	2.49
12	Congenital generalized lipodystrophy	Enrichment	PPARG	2.49
13	Enchondromatosis, multiple, ollier type	Enrichment	HIF1A	2.39
14	Rhabdomyosarcoma 2	Enrichment	FOXO1	2.39
15	Multiple enchondromatosis, maffucci type	Enrichment	HIF1A	2.25
16	Common variable immunodeficiency	Enrichment	NFKB1	2.25
17	Ciliary dyskinesia, primary, 3	Enrichment	NFKB1	2.09
18	Lung cancer susceptibility 3	Enrichment	ROS1	1.95
19	Gliosarcoma	Enrichment	PPARG	1.89
20	Diffuse large b-cell lymphoma	Enrichment	FOXO1	1.82
21	Differentiated thyroid carcinoma	Enrichment	PPARG	1.63
22	Type 2 diabetes mellitus	Enrichment	PPARG	1.47
23	Body mass index quantitative trait locus 11	Enrichment	PPARG	1.40
24	Colorectal cancer	Enrichment	PPARG	1.17

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Pathway Network for NAD metabolism, sirtuins and aging