Nanog in Mammalian ESC Pluripotency

Pathway network for the Nanog in Mammalian ESC Pluripotency SuperPath

Sources:

QIAGEN

Pathways in the Nanog in Mammalian ESC Pluripotency SuperPath

#	Name	Source	Genes
1	Nanog in Mammalian ESC Pluripotency	QIAGEN	ALK ANGPTL6 APC ARAF AREG AXIN1 AXL BDNF BMP1 BMP10 BMP2 BMP3 BMP4 BMP5 BMP6 BMP7 BMP8A BRAF BTC CCN2 CLEC11A CRIPTO CSF1R CTNNB1 CXCL12 DDR1 DDR2 DRC4 DVL1 EGF EGFR EPHA1 EPHA2 EPHA3 EPHA4 EPHA5 EPHA7 EPHA8 EPHB1 EPHB2 EPHB3 EPHB4 EPHB6 EPOR ERBB2 ERBB3 ERBB4 FGF1 FGF10 FGF11 FGF12 FGF13 FGF14 FGF16 FGF17 FGF18 FGF19 FGF2 FGF20 FGF21 FGF22 FGF23 FGF4 FGF5 FGF6 FGF7 FGF8 FGFR1 FGFR2 FGFR3 FGFR4 FLT1 FLT3 FLT4 FOXD3 FZD1 FZD10 FZD2 FZD3 FZD4 FZD5 FZD6 FZD7 FZD8 FZD9 GAS1 GAS2 GAS6 GDF10 GDF15 GDF2 GDF5 GDF6 GDF9 GFER GH1 GH2 GHRH GMFG GNRH1 GNRH2 GPC6 GRB2 GSK3B HDGF HGF HRAS IGF1 IGF1R IGF2 IGF2-AS IL2 IL3 IL6 IL9 INSR INSRR KDR KIT KITLG KLF10 KRAS LEFTY1 LEFTY2 LHB LIFR LMTK2 LMTK3 LTBP1 LTBP2 LTBP3 LTBP4 MAP2K1 MAP2K2 MAPK1 MAPK3 MDK MERTK MET MRAS MST1R MUSK NANOG NGF NRAS NRG1 NRG2 NRG3 NTF3 NTF4 NTRK1 NTRK2 NTRK3 NUDT6 OGN PDGFA PDGFB PDGFC PDGFD PDGFRA PDGFRB PENK PGF PLPP3 POU5F1 PPBP PROK1 PSIP1 PTK7 PTN RAF1 ROR1 ROR2 ROS1 RRAS RRAS2 RYK SEMA3A SEMA4B SEMA4G SEMA5A SOS1 SOS2 SOX2 SPON1 TBRG1 TEK TGFA TGFB1 TGFB2 TGFB3 THPO TIE1 TIMP1 TIMP2 TIMP3 TIMP4 TYMP TYRO3 UTS2 VEGFB VEGFC VEGFD WNT1 WNT10A WNT10B WNT11 WNT16 WNT2 WNT2B WNT3 WNT3A WNT4 WNT5A WNT5B WNT6 WNT7A WNT7B WNT8A WNT8B WNT9A WNT9B (see all 222) (see less)
2	GSK3 Signaling	QIAGEN	AGO1 AGO2 AKT1 ALK ANGPTL6 APC AREG AXIN1 AXL BDNF BMP1 BMP10 BMP2 BMP3 BMP4 BMP5 BMP6 BMP7 BMP8A BTC BTRC CCN2 CDH1 CDH10 CDH11 CDH12 CDH13 CDH15 CDH16 CDH17 CDH18 CDH19 CDH2 CDH20 CDH22 CDH23 CDH24 CDH26 CDH3 CDH4 CDH5 CDH6 CDH7 CDH8 CDH9 CLEC11A CREBBP CRIPTO CSF1R CSNK1A1 CSNK1D CSNK1E CSNK1G1 CSNK1G2 CSNK1G3 CSNK2A1 CSNK2A2 CTBP1 CTBP2 CTNNB1 CXCL12 DCHS1 DDR1 DDR2 DRC4 DVL1 EGF EGFR EIF2A EIF2AK3 EIF2AK4 EIF2B1 EIF2B2 EIF2B3 EIF2B4 EIF2B5 EIF2S1 EIF2S2 EIF2S3 EPHA1 EPHA2 EPHA3 EPHA4 EPHA5 EPHA7 EPHA8 EPHB1 EPHB2 EPHB3 EPHB4 EPHB6 EPOR ERBB2 ERBB3 ERBB4 FGF1 FGF10 FGF11 FGF12 FGF13 FGF14 FGF16 FGF17 FGF18 FGF19 FGF2 FGF20 FGF21 FGF22 FGF23 FGF4 FGF5 FGF6 FGF7 FGF8 FGFR1 FGFR2 FGFR3 FGFR4 FLT1 FLT3 FLT4 FRAT1 FRAT2 FZD1 FZD10 FZD2 FZD3 FZD4 FZD5 FZD6 FZD7 FZD8 FZD9 GAS1 GAS2 GAS6 GDF10 GDF15 GDF2 GDF5 GDF6 GDF9 GFER GH1 GH2 GHRH GMFG GNAO1 GNRH1 GNRH2 GPC6 GSK3A GSK3B HDGF HGF HRAS IGF1 IGF1R IGF2 IGF2-AS IL2 IL3 IL6 IL9 INSR INSRR KDR KIT KITLG KLF10 KRAS LEF1 LEFTY1 LEFTY2 LHB LIFR LMTK2 LMTK3 LTBP1 LTBP2 LTBP3 LTBP4 MAPK1 MAPK10 MAPK11 MAPK12 MAPK13 MAPK14 MAPK3 MAPK4 MAPK6 MAPK7 MAPK8 MAPK9 MDK MERTK MET MRAS MST1R MUSK NGF NRAS NRG1 NRG2 NRG3 NTF3 NTF4 NTRK1 NTRK2 NTRK3 NUDT6 OGN PDGFA PDGFB PDGFC PDGFD PDGFRA PDGFRB PENK PGF PIK3R1 PIK3R2 PIK3R3 PIK3R4 PIK3R5 PLPP3 PPBP PPP2CA PPP2CB PPP2R1A PPP2R1B PPP2R2A PPP2R2B PPP2R2C PPP2R3A PPP2R3B PPP2R5A PPP2R5B PPP2R5C PPP2R5E PROK1 PSIP1 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB10 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMB8 PSMB9 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD7 PTK7 PTN PTPA ROR1 ROR2 ROS1 RPS6KA1 RPS6KA3 RRAS RRAS2 RYK SEMA3A SEMA4B SEMA4G SEMA5A SPON1 TBRG1 TCF7 TEK TGFA TGFB1 TGFB2 TGFB3 THPO TIE1 TIMP1 TIMP2 TIMP3 TIMP4 TLE1 TLE2 TLE3 TYMP TYRO3 UTS2 VEGFB VEGFC VEGFD WNT1 WNT10A WNT10B WNT11 WNT16 WNT2 WNT2B WNT3 WNT3A WNT4 WNT5A WNT5B WNT6 WNT7A WNT7B WNT8A WNT8B WNT9A WNT9B (see all 330) (see less)
3	eNOS Signaling	QIAGEN	ACTA1 ACTA2 ACTB ACTG1 ACTG2 ADCY1 ADCY2 ADCY3 ADCY4 ADCY5 ADCY6 ADCY7 ADCY8 ADCY9 AKT1 ALK ANGPTL6 AQP1 AQP10 AQP11 AQP12A AQP12B AQP2 AQP3 AQP4 AQP5 AQP6 AQP7 AQP8 AQP9 AREG AXL BDKRB1 BDKRB2 BDNF BMP1 BMP10 BMP2 BMP3 BMP4 BMP5 BMP6 BMP7 BMP8A BTC CALM1 CALM2 CALM3 CASP3 CASP8 CAV1 CCN2 CCNA1 CCNA2 CHRNA1 CHRNA10 CHRNA2 CHRNA3 CHRNA4 CHRNA5 CHRNA6 CHRNA7 CHRNA9 CHRNB1 CHRNB2 CHRNB3 CHRNB4 CHRND CHRNE CHRNG CLEC11A CNGA1 CNGA3 CNGA4 CNGB1 CNGB3 CRIPTO CSF1R CXCL12 DDR1 DDR2 DNM2 DRC4 EGF EGFR EPHA1 EPHA2 EPHA3 EPHA4 EPHA5 EPHA7 EPHA8 EPHB1 EPHB2 EPHB3 EPHB4 EPHB6 EPOR ERBB2 ERBB3 ERBB4 ESR1 ESR2 FGF1 FGF10 FGF11 FGF12 FGF13 FGF14 FGF16 FGF17 FGF18 FGF19 FGF2 FGF20 FGF21 FGF22 FGF23 FGF4 FGF5 FGF6 FGF7 FGF8 FGFR1 FGFR2 FGFR3 FGFR4 FLT1 FLT3 FLT4 GAS1 GAS2 GAS6 GDF10 GDF15 GDF2 GDF5 GDF6 GDF9 GFER GH1 GH2 GHRH GMFG GNAI1 GNAI2 GNAI3 GNAS GNB1 GNB2 GNB3 GNB4 GNB5 GNG2 GNG3 GNG4 GNRH1 GNRH2 GPC6 GUCY1A1 GUCY1A2 GUCY1B1 GUCY2C GUCY2D GUCY2EP GUCY2F HDGF HGF HSP90AA1 HSPA4 IGF1 IGF1R IGF2 IGF2-AS IL2 IL3 IL6 IL9 INSR INSRR ITPR1 ITPR2 ITPR3 KDR KIT KITLG KLF10 LEFTY1 LEFTY2 LHB LIFR LMTK2 LMTK3 LPAR1 LPAR2 LPAR3 LTBP1 LTBP2 LTBP3 LTBP4 MDK MERTK MET MST1R MUSK NGF NOS3 NOSIP NOSTRIN NPR1 NPR2 NRG1 NRG2 NRG3 NTF3 NTF4 NTRK1 NTRK2 NTRK3 NUDT6 OGN PDGFA PDGFB PDGFC PDGFD PDGFRA PDGFRB PDK1 PDK2 PDK3 PDK4 PENK PGF PIK3R1 PIK3R2 PIK3R3 PIK3R4 PIK3R5 PLCG1 PLCG2 PLPP3 PPBP PRKAA1 PRKAA2 PRKAB1 PRKAB2 PRKACA PRKACB PRKACG PRKAG1 PRKAG2 PRKAG3 PRKAR1A PRKAR1B PRKAR2A PRKAR2B PRKG1 PROK1 PSIP1 PTK7 PTN ROR1 ROR2 ROS1 RYK S1PR1 S1PR2 S1PR3 S1PR4 S1PR5 SEMA3A SEMA4B SEMA4G SEMA5A SLC7A1 SPON1 STUB1 TBRG1 TEK TGFA TGFB1 TGFB2 TGFB3 THPO TIE1 TIMP1 TIMP2 TIMP3 TIMP4 TYMP TYRO3 UTS2 VEGFA VEGFB VEGFC VEGFD (see all 296) (see less)
4	14-3-3 Induced Intracellular Signaling	QIAGEN	AKT1 AKT1S1 ALK ANGPTL6 AREG AXL BAD BDNF BMP1 BMP10 BMP2 BMP3 BMP4 BMP5 BMP6 BMP7 BMP8A BTC CBL CCN2 CD55 CLEC11A CRIPTO CSF1R CXCL12 DDR1 DDR2 DRC4 EGF EGFR ELK1 EPHA1 EPHA2 EPHA3 EPHA4 EPHA5 EPHA7 EPHA8 EPHB1 EPHB2 EPHB3 EPHB4 EPHB6 EPOR ERBB2 ERBB3 ERBB4 FGF1 FGF10 FGF11 FGF12 FGF13 FGF14 FGF16 FGF17 FGF18 FGF19 FGF2 FGF20 FGF21 FGF22 FGF23 FGF4 FGF5 FGF6 FGF7 FGF8 FGFR1 FGFR2 FGFR3 FGFR4 FLT1 FLT3 FLT4 FOS GAS1 GAS2 GAS6 GDF10 GDF15 GDF2 GDF5 GDF6 GDF9 GFER GH1 GH2 GHRH GMFG GNRH1 GNRH2 GPC6 GRB2 GSK3B HDGF HGF HRAS IGF1 IGF1R IGF2 IGF2-AS IL2 IL3 IL6 IL9 INSR INSRR JUN KDR KIT KITLG KLF10 KRAS LEFTY1 LEFTY2 LHB LIFR LMTK2 LMTK3 LTBP1 LTBP2 LTBP3 LTBP4 MAP2K1 MAP2K2 MAP2K3 MAP2K4 MAP2K5 MAP2K6 MAP3K5 MAPK1 MAPK10 MAPK11 MAPK12 MAPK13 MAPK14 MAPK3 MAPK6 MAPK7 MAPK8 MAPK9 MAPT MDK MERTK MET MRAS MST1R MUSK NGF NRAS NRG1 NRG2 NRG3 NTF3 NTF4 NTRK1 NTRK2 NTRK3 NUDT6 OGN PDGFA PDGFB PDGFC PDGFD PDGFRA PDGFRB PENK PGF PIK3R1 PIK3R2 PIK3R3 PIK3R4 PIK3R5 PLCB1 PLCB2 PLCB3 PLCB4 PLCD1 PLCD3 PLCD4 PLCE1 PLCG1 PLCG2 PLCZ1 PLPP3 PPBP PRKCA PRKCB PRKCD PRKCE PRKCG PRKCH PRKCI PRKCQ PRKCZ PRKD1 PRKD3 PROK1 PSIP1 PTK7 PTN RAF1 ROR1 ROR2 ROS1 RPS6KA1 RPS6KA2 RPS6KA3 RPS6KA4 RPS6KA5 RPS6KA6 RPS6KB1 RPS6KB2 RPS6KC1 RRAS RRAS2 RYK SEMA3A SEMA4B SEMA4G SEMA5A SNCA SPON1 SRC TBRG1 TEK TGFA TGFB1 TGFB2 TGFB3 THPO TIE1 TIMP1 TIMP2 TIMP3 TIMP4 TNF TNFRSF1A TP73 TRAF2 TSC1 TSC2 TUBA3C TUBA4A TUBA8 TUBB1 TUBB2A TUBB7P TUBE1 TUBG1 TUBG2 TUBGCP2 TUBGCP3 TUBGCP5 TUBGCP6 TYMP TYRO3 UTS2 VEGFB VEGFC VEGFD VIM YAP1 YWHAB YWHAE YWHAG YWHAH YWHAQ YWHAZ (see all 269) (see less)

Gene overlap in member pathways for Nanog in Mammalian ESC Pluripotency SuperPath

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	ALK	ALK Receptor Tyrosine Kinase	Protein Coding	4
2	ANGPTL6	Angiopoietin Like 6	Protein Coding	4
3	AREG	Amphiregulin	Protein Coding	4
4	AXL	AXL Receptor Tyrosine Kinase	Protein Coding	4
5	BDNF	Brain Derived Neurotrophic Factor	Protein Coding	4
6	BMP1	Bone Morphogenetic Protein 1	Protein Coding	4
7	BMP10	Bone Morphogenetic Protein 10	Protein Coding	4
8	BMP2	Bone Morphogenetic Protein 2	Protein Coding	4
9	BMP3	Bone Morphogenetic Protein 3	Protein Coding	4
10	BMP4	Bone Morphogenetic Protein 4	Protein Coding	4
11	BMP5	Bone Morphogenetic Protein 5	Protein Coding	4
12	BMP6	Bone Morphogenetic Protein 6	Protein Coding	4
13	BMP7	Bone Morphogenetic Protein 7	Protein Coding	4
14	BMP8A	Bone Morphogenetic Protein 8a	Protein Coding	4
15	BTC	Betacellulin	Protein Coding	4
16	CSF1R	Colony Stimulating Factor 1 Receptor	Protein Coding	4
17	CCN2	Cellular Communication Network Factor 2	Protein Coding	4
18	CXCL12	C-X-C Motif Chemokine Ligand 12	Protein Coding	4
19	DDR1	Discoidin Domain Receptor Tyrosine Kinase 1	Protein Coding	4
20	DDR2	Discoidin Domain Receptor Tyrosine Kinase 2	Protein Coding	4
21	LEFTY2	Left-Right Determination Factor 2	Protein Coding	4
22	TYMP	Thymidine Phosphorylase	Protein Coding	4
23	EGF	Epidermal Growth Factor	Protein Coding	4
24	EGFR	Epidermal Growth Factor Receptor	Protein Coding	4
25	EPHA1	EPH Receptor A1	Protein Coding	4
26	EPHA2	EPH Receptor A2	Protein Coding	4
27	EPHA3	EPH Receptor A3	Protein Coding	4
28	EPHA4	EPH Receptor A4	Protein Coding	4
29	EPHA5	EPH Receptor A5	Protein Coding	4
30	EPHA7	EPH Receptor A7	Protein Coding	4
31	EPHA8	EPH Receptor A8	Protein Coding	4
32	EPHB1	EPH Receptor B1	Protein Coding	4
33	EPHB2	EPH Receptor B2	Protein Coding	4
34	EPHB3	EPH Receptor B3	Protein Coding	4
35	EPHB4	EPH Receptor B4	Protein Coding	4
36	EPHB6	EPH Receptor B6	Protein Coding	4
37	EPOR	Erythropoietin Receptor	Protein Coding	4
38	ERBB2	Erb-B2 Receptor Tyrosine Kinase 2	Protein Coding	4
39	ERBB3	Erb-B2 Receptor Tyrosine Kinase 3	Protein Coding	4
40	ERBB4	Erb-B2 Receptor Tyrosine Kinase 4	Protein Coding	4
41	FGF1	Fibroblast Growth Factor 1	Protein Coding	4
42	FGF10	Fibroblast Growth Factor 10	Protein Coding	4
43	FGF11	Fibroblast Growth Factor 11	Protein Coding	4
44	FGF12	Fibroblast Growth Factor 12	Protein Coding	4
45	FGF13	Fibroblast Growth Factor 13	Protein Coding	4
46	FGF14	Fibroblast Growth Factor 14	Protein Coding	4
47	FGF16	Fibroblast Growth Factor 16	Protein Coding	4
48	FGF17	Fibroblast Growth Factor 17	Protein Coding	4
49	FGF18	Fibroblast Growth Factor 18	Protein Coding	4
50	FGF19	Fibroblast Growth Factor 19	Protein Coding	4
51	FGF2	Fibroblast Growth Factor 2	Protein Coding	4
52	FGF20	Fibroblast Growth Factor 20	Protein Coding	4
53	FGF21	Fibroblast Growth Factor 21	Protein Coding	4
54	FGF22	Fibroblast Growth Factor 22	Protein Coding	4
55	FGF23	Fibroblast Growth Factor 23	Protein Coding	4
56	FGF4	Fibroblast Growth Factor 4	Protein Coding	4
57	FGF5	Fibroblast Growth Factor 5	Protein Coding	4
58	FGF6	Fibroblast Growth Factor 6	Protein Coding	4
59	FGF7	Fibroblast Growth Factor 7	Protein Coding	4
60	FGF8	Fibroblast Growth Factor 8	Protein Coding	4
61	FGFR1	Fibroblast Growth Factor Receptor 1	Protein Coding	4
62	FGFR2	Fibroblast Growth Factor Receptor 2	Protein Coding	4
63	FGFR3	Fibroblast Growth Factor Receptor 3	Protein Coding	4
64	FGFR4	Fibroblast Growth Factor Receptor 4	Protein Coding	4
65	VEGFD	Vascular Endothelial Growth Factor D	Protein Coding	4
66	FLT1	Fms Related Receptor Tyrosine Kinase 1	Protein Coding	4
67	FLT3	Fms Related Receptor Tyrosine Kinase 3	Protein Coding	4
68	FLT4	Fms Related Receptor Tyrosine Kinase 4	Protein Coding	4
69	GAS1	Growth Arrest Specific 1	Protein Coding	4
70	GAS2	Growth Arrest Specific 2	Protein Coding	4
71	GAS6	Growth Arrest Specific 6	Protein Coding	4
72	DRC4	Dynein Regulatory Complex Subunit 4	Protein Coding	4
73	GDF10	Growth Differentiation Factor 10	Protein Coding	4
74	GDF2	Growth Differentiation Factor 2	Protein Coding	4
75	GDF5	Growth Differentiation Factor 5	Protein Coding	4
76	GDF6	Growth Differentiation Factor 6	Protein Coding	4
77	GDF9	Growth Differentiation Factor 9	Protein Coding	4
78	GFER	Growth Factor, Augmenter Of Liver Regeneration	Protein Coding	4
79	GH1	Growth Hormone 1	Protein Coding	4
80	GH2	Growth Hormone 2	Protein Coding	4
81	GHRH	Growth Hormone Releasing Hormone	Protein Coding	4
82	GMFG	Glia Maturation Factor Gamma	Protein Coding	4
83	GNRH1	Gonadotropin Releasing Hormone 1	Protein Coding	4
84	GNRH2	Gonadotropin Releasing Hormone 2	Protein Coding	4
85	GPC6	Glypican 6	Protein Coding	4
86	HDGF	Heparin Binding Growth Factor	Protein Coding	4
87	HGF	Hepatocyte Growth Factor	Protein Coding	4
88	IGF1	Insulin Like Growth Factor 1	Protein Coding	4
89	IGF1R	Insulin Like Growth Factor 1 Receptor	Protein Coding	4
90	IGF2	Insulin Like Growth Factor 2	Protein Coding	4
91	IGF2-AS	IGF2 Antisense RNA	RNA Gene	4
92	IL2	Interleukin 2	Protein Coding	4
93	IL3	Interleukin 3	Protein Coding	4
94	IL6	Interleukin 6	Protein Coding	4
95	IL9	Interleukin 9	Protein Coding	4
96	INSR	Insulin Receptor	Protein Coding	4
97	INSRR	Insulin Receptor Related Receptor	Protein Coding	4
98	KDR	Kinase Insert Domain Receptor	Protein Coding	4
99	KIT	KIT Proto-Oncogene, Receptor Tyrosine Kinase	Protein Coding	4
100	KITLG	KIT Ligand	Protein Coding	4
101	LEFTY1	Left-Right Determination Factor 1	Protein Coding	4
102	LHB	Luteinizing Hormone Subunit Beta	Protein Coding	4
103	LIFR	LIF Receptor Subunit Alpha	Protein Coding	4
104	LMTK2	Lemur Tyrosine Kinase 2	Protein Coding	4
105	LMTK3	Lemur Tyrosine Kinase 3	Protein Coding	4
106	LTBP1	Latent Transforming Growth Factor Beta Binding Protein 1	Protein Coding	4
107	LTBP2	Latent Transforming Growth Factor Beta Binding Protein 2	Protein Coding	4
108	LTBP3	Latent Transforming Growth Factor Beta Binding Protein 3	Protein Coding	4
109	LTBP4	Latent Transforming Growth Factor Beta Binding Protein 4	Protein Coding	4
110	MDK	Midkine	Protein Coding	4
111	MERTK	MER Proto-Oncogene, Tyrosine Kinase	Protein Coding	4
112	MET	MET Proto-Oncogene, Receptor Tyrosine Kinase	Protein Coding	4
113	MST1R	Macrophage Stimulating 1 Receptor	Protein Coding	4
114	MUSK	Muscle Associated Receptor Tyrosine Kinase	Protein Coding	4
115	NGF	Nerve Growth Factor	Protein Coding	4
116	NRG1	Neuregulin 1	Protein Coding	4
117	NRG2	Neuregulin 2	Protein Coding	4
118	NRG3	Neuregulin 3	Protein Coding	4
119	NTF3	Neurotrophin 3	Protein Coding	4
120	NTF4	Neurotrophin 4	Protein Coding	4
121	NTRK1	Neurotrophic Receptor Tyrosine Kinase 1	Protein Coding	4
122	NTRK2	Neurotrophic Receptor Tyrosine Kinase 2	Protein Coding	4
123	NTRK3	Neurotrophic Receptor Tyrosine Kinase 3	Protein Coding	4
124	NUDT6	Nudix Hydrolase 6	Protein Coding	4
125	OGN	Osteoglycin	Protein Coding	4
126	PDGFA	Platelet Derived Growth Factor Subunit A	Protein Coding	4
127	PDGFB	Platelet Derived Growth Factor Subunit B	Protein Coding	4
128	PDGFC	Platelet Derived Growth Factor C	Protein Coding	4
129	PDGFRA	Platelet Derived Growth Factor Receptor Alpha	Protein Coding	4
130	PDGFRB	Platelet Derived Growth Factor Receptor Beta	Protein Coding	4
131	PENK	Proenkephalin	Protein Coding	4
132	PGF	Placental Growth Factor	Protein Coding	4
133	GDF15	Growth Differentiation Factor 15	Protein Coding	4
134	PLPP3	Phospholipid Phosphatase 3	Protein Coding	4
135	PPBP	Pro-Platelet Basic Protein	Protein Coding	4
136	PROK1	Prokineticin 1	Protein Coding	4
137	PSIP1	PC4 And SRSF1 Interacting Protein 1	Protein Coding	4
138	PTK7	Protein Tyrosine Kinase 7 (Inactive)	Protein Coding	4
139	PTN	Pleiotrophin	Protein Coding	4
140	ROR1	Receptor Tyrosine Kinase Like Orphan Receptor 1	Protein Coding	4
141	ROR2	Receptor Tyrosine Kinase Like Orphan Receptor 2	Protein Coding	4
142	ROS1	ROS Proto-Oncogene 1, Receptor Tyrosine Kinase	Protein Coding	4
143	RYK	Receptor Like Tyrosine Kinase	Protein Coding	4
144	PDGFD	Platelet Derived Growth Factor D	Protein Coding	4
145	CLEC11A	C-Type Lectin Domain Containing 11A	Protein Coding	4
146	SEMA3A	Semaphorin 3A	Protein Coding	4
147	SEMA4B	Semaphorin 4B	Protein Coding	4
148	SEMA4G	Semaphorin 4G	Protein Coding	4
149	SEMA5A	Semaphorin 5A	Protein Coding	4
150	SPON1	Spondin 1	Protein Coding	4
151	TBRG1	Transforming Growth Factor Beta Regulator 1	Protein Coding	4
152	CRIPTO	Cripto, EGF-CFC Family Member	Protein Coding	4
153	TEK	TEK Receptor Tyrosine Kinase	Protein Coding	4
154	TGFA	Transforming Growth Factor Alpha	Protein Coding	4
155	TGFB1	Transforming Growth Factor Beta 1	Protein Coding	4
156	TGFB2	Transforming Growth Factor Beta 2	Protein Coding	4
157	TGFB3	Transforming Growth Factor Beta 3	Protein Coding	4
158	THPO	Thrombopoietin	Protein Coding	4
159	TIE1	Tyrosine Kinase With Immunoglobulin Like And EGF Like Domains 1	Protein Coding	4
160	KLF10	KLF Transcription Factor 10	Protein Coding	4
161	TIMP1	TIMP Metallopeptidase Inhibitor 1	Protein Coding	4
162	TIMP2	TIMP Metallopeptidase Inhibitor 2	Protein Coding	4
163	TIMP3	TIMP Metallopeptidase Inhibitor 3	Protein Coding	4
164	TIMP4	TIMP Metallopeptidase Inhibitor 4	Protein Coding	4
165	TYRO3	TYRO3 Protein Tyrosine Kinase	Protein Coding	4
166	UTS2	Urotensin 2	Protein Coding	4
167	VEGFB	Vascular Endothelial Growth Factor B	Protein Coding	4
168	VEGFC	Vascular Endothelial Growth Factor C	Protein Coding	4
169	GSK3B	Glycogen Synthase Kinase 3 Beta	Protein Coding	3
170	HRAS	HRas Proto-Oncogene, GTPase	Protein Coding	3
171	KRAS	KRAS Proto-Oncogene, GTPase	Protein Coding	3
172	MAPK1	Mitogen-Activated Protein Kinase 1	Protein Coding	3
173	MAPK3	Mitogen-Activated Protein Kinase 3	Protein Coding	3
174	MRAS	Muscle RAS Oncogene Homolog	Protein Coding	3
175	NRAS	NRAS Proto-Oncogene, GTPase	Protein Coding	3
176	RRAS	RAS Related	Protein Coding	3
177	RRAS2	RAS Related 2	Protein Coding	3
178	AKT1	AKT Serine/Threonine Kinase 1	Protein Coding	3
179	PIK3R5	Phosphoinositide-3-Kinase Regulatory Subunit 5	Protein Coding	3
180	PIK3R1	Phosphoinositide-3-Kinase Regulatory Subunit 1	Protein Coding	3
181	PIK3R2	Phosphoinositide-3-Kinase Regulatory Subunit 2	Protein Coding	3
182	PIK3R3	Phosphoinositide-3-Kinase Regulatory Subunit 3	Protein Coding	3
183	PIK3R4	Phosphoinositide-3-Kinase Regulatory Subunit 4	Protein Coding	3
184	APC	APC Regulator Of Wnt Signaling Pathway	Protein Coding	2
185	AXIN1	Axin 1	Protein Coding	2
186	CTNNB1	Catenin Beta 1	Protein Coding	2
187	DVL1	Dishevelled Segment Polarity Protein 1	Protein Coding	2
188	FZD1	Frizzled Class Receptor 1	Protein Coding	2
189	FZD10	Frizzled Class Receptor 10	Protein Coding	2
190	FZD2	Frizzled Class Receptor 2	Protein Coding	2
191	FZD3	Frizzled Class Receptor 3	Protein Coding	2
192	FZD4	Frizzled Class Receptor 4	Protein Coding	2
193	FZD5	Frizzled Class Receptor 5	Protein Coding	2
194	FZD6	Frizzled Class Receptor 6	Protein Coding	2
195	FZD7	Frizzled Class Receptor 7	Protein Coding	2
196	FZD8	Frizzled Class Receptor 8	Protein Coding	2
197	FZD9	Frizzled Class Receptor 9	Protein Coding	2
198	GRB2	Growth Factor Receptor Bound Protein 2	Protein Coding	2
199	MAP2K1	Mitogen-Activated Protein Kinase Kinase 1	Protein Coding	2
200	MAP2K2	Mitogen-Activated Protein Kinase Kinase 2	Protein Coding	2
201	RAF1	Raf-1 Proto-Oncogene, Serine/Threonine Kinase	Protein Coding	2
202	WNT1	Wnt Family Member 1	Protein Coding	2
203	WNT10A	Wnt Family Member 10A	Protein Coding	2
204	WNT10B	Wnt Family Member 10B	Protein Coding	2
205	WNT11	Wnt Family Member 11	Protein Coding	2
206	WNT9A	Wnt Family Member 9A	Protein Coding	2
207	WNT9B	Wnt Family Member 9B	Protein Coding	2
208	WNT16	Wnt Family Member 16	Protein Coding	2
209	WNT2	Wnt Family Member 2	Protein Coding	2
210	WNT2B	Wnt Family Member 2B	Protein Coding	2
211	WNT3	Wnt Family Member 3	Protein Coding	2
212	WNT3A	Wnt Family Member 3A	Protein Coding	2
213	WNT4	Wnt Family Member 4	Protein Coding	2
214	WNT5A	Wnt Family Member 5A	Protein Coding	2
215	WNT5B	Wnt Family Member 5B	Protein Coding	2
216	WNT6	Wnt Family Member 6	Protein Coding	2
217	WNT7A	Wnt Family Member 7A	Protein Coding	2
218	WNT7B	Wnt Family Member 7B	Protein Coding	2
219	WNT8A	Wnt Family Member 8A	Protein Coding	2
220	WNT8B	Wnt Family Member 8B	Protein Coding	2
221	MAPK10	Mitogen-Activated Protein Kinase 10	Protein Coding	2
222	MAPK11	Mitogen-Activated Protein Kinase 11	Protein Coding	2
223	MAPK12	Mitogen-Activated Protein Kinase 12	Protein Coding	2
224	MAPK13	Mitogen-Activated Protein Kinase 13	Protein Coding	2
225	MAPK14	Mitogen-Activated Protein Kinase 14	Protein Coding	2
226	MAPK6	Mitogen-Activated Protein Kinase 6	Protein Coding	2
227	MAPK7	Mitogen-Activated Protein Kinase 7	Protein Coding	2
228	MAPK8	Mitogen-Activated Protein Kinase 8	Protein Coding	2
229	MAPK9	Mitogen-Activated Protein Kinase 9	Protein Coding	2
230	RPS6KA1	Ribosomal Protein S6 Kinase A1	Protein Coding	2
231	RPS6KA3	Ribosomal Protein S6 Kinase A3	Protein Coding	2
232	PLCG1	Phospholipase C Gamma 1	Protein Coding	2
233	PLCG2	Phospholipase C Gamma 2	Protein Coding	2
234	ARAF	A-Raf Proto-Oncogene, Serine/Threonine Kinase	Protein Coding	1
235	BRAF	B-Raf Proto-Oncogene, Serine/Threonine Kinase	Protein Coding	1
236	FOXD3	Forkhead Box D3	Protein Coding	1
237	NANOG	Nanog Homeobox	Protein Coding	1
238	POU5F1	POU Class 5 Homeobox 1	Protein Coding	1
239	SOS1	SOS Ras/Rac Guanine Nucleotide Exchange Factor 1	Protein Coding	1
240	SOS2	SOS Ras/Rho Guanine Nucleotide Exchange Factor 2	Protein Coding	1
241	SOX2	SRY-Box Transcription Factor 2	Protein Coding	1
242	BTRC	Beta-Transducin Repeat Containing E3 Ubiquitin Protein Ligase	Protein Coding	1
243	CDH1	Cadherin 1	Protein Coding	1
244	CDH10	Cadherin 10	Protein Coding	1
245	CDH11	Cadherin 11	Protein Coding	1
246	CDH12	Cadherin 12	Protein Coding	1
247	CDH13	Cadherin 13	Protein Coding	1
248	CDH15	Cadherin 15	Protein Coding	1
249	CDH16	Cadherin 16	Protein Coding	1
250	CDH17	Cadherin 17	Protein Coding	1
251	CDH18	Cadherin 18	Protein Coding	1
252	CDH19	Cadherin 19	Protein Coding	1
253	CDH2	Cadherin 2	Protein Coding	1
254	CDH20	Cadherin 20	Protein Coding	1
255	CDH22	Cadherin 22	Protein Coding	1
256	CDH23	Cadherin Related 23	Protein Coding	1
257	CDH24	Cadherin 24	Protein Coding	1
258	CDH26	Cadherin 26	Protein Coding	1
259	CDH3	Cadherin 3	Protein Coding	1
260	CDH4	Cadherin 4	Protein Coding	1
261	CDH5	Cadherin 5	Protein Coding	1
262	CDH6	Cadherin 6	Protein Coding	1
263	CDH7	Cadherin 7	Protein Coding	1
264	CDH8	Cadherin 8	Protein Coding	1
265	CDH9	Cadherin 9	Protein Coding	1
266	CREBBP	CREB Binding Lysine Acetyltransferase	Protein Coding	1
267	CSNK1A1	Casein Kinase 1 Alpha 1	Protein Coding	1
268	CSNK1D	Casein Kinase 1 Delta	Protein Coding	1
269	CSNK1E	Casein Kinase 1 Epsilon	Protein Coding	1
270	CSNK1G1	Casein Kinase 1 Gamma 1	Protein Coding	1
271	CSNK1G2	Casein Kinase 1 Gamma 2	Protein Coding	1
272	CSNK1G3	Casein Kinase 1 Gamma 3	Protein Coding	1
273	CSNK2A1	Casein Kinase 2 Alpha 1	Protein Coding	1
274	CSNK2A2	Casein Kinase 2 Alpha 2	Protein Coding	1
275	CTBP1	C-Terminal Binding Protein 1	Protein Coding	1
276	CTBP2	C-Terminal Binding Protein 2	Protein Coding	1
277	EIF2A	Eukaryotic Translation Initiation Factor 2A	Protein Coding	1
278	EIF2AK3	Eukaryotic Translation Initiation Factor 2 Alpha Kinase 3	Protein Coding	1
279	EIF2AK4	Eukaryotic Translation Initiation Factor 2 Alpha Kinase 4	Protein Coding	1
280	EIF2B1	Eukaryotic Translation Initiation Factor 2B Subunit Alpha	Protein Coding	1
281	EIF2B2	Eukaryotic Translation Initiation Factor 2B Subunit Beta	Protein Coding	1
282	EIF2B3	Eukaryotic Translation Initiation Factor 2B Subunit Gamma	Protein Coding	1
283	EIF2B4	Eukaryotic Translation Initiation Factor 2B Subunit Delta	Protein Coding	1
284	EIF2B5	Eukaryotic Translation Initiation Factor 2B Subunit Epsilon	Protein Coding	1
285	AGO1	Argonaute RISC Component 1	Protein Coding	1
286	AGO2	Argonaute RISC Catalytic Component 2	Protein Coding	1
287	EIF2S1	Eukaryotic Translation Initiation Factor 2 Subunit Alpha	Protein Coding	1
288	EIF2S2	Eukaryotic Translation Initiation Factor 2 Subunit Beta	Protein Coding	1
289	EIF2S3	Eukaryotic Translation Initiation Factor 2 Subunit Gamma	Protein Coding	1
290	FRAT1	FRAT Regulator Of Wnt Signaling Pathway 1	Protein Coding	1
291	FRAT2	FRAT Regulator Of Wnt Signaling Pathway 2	Protein Coding	1
292	GNAO1	G Protein Subunit Alpha O1	Protein Coding	1
293	GSK3A	Glycogen Synthase Kinase 3 Alpha	Protein Coding	1
294	LEF1	Lymphoid Enhancer Binding Factor 1	Protein Coding	1
295	MAPK4	Mitogen-Activated Protein Kinase 4	Protein Coding	1
296	PSMD6	Proteasome 26S Subunit, Non-ATPase 6	Protein Coding	1
297	DCHS1	Dachsous Cadherin-Related 1	Protein Coding	1
298	PPP2CA	Protein Phosphatase 2 Catalytic Subunit Alpha	Protein Coding	1
299	PPP2CB	Protein Phosphatase 2 Catalytic Subunit Beta	Protein Coding	1
300	PPP2R1A	Protein Phosphatase 2 Scaffold Subunit Aalpha	Protein Coding	1
301	PPP2R1B	Protein Phosphatase 2 Scaffold Subunit Abeta	Protein Coding	1
302	PPP2R2A	Protein Phosphatase 2 Regulatory Subunit Balpha	Protein Coding	1
303	PPP2R2B	Protein Phosphatase 2 Regulatory Subunit Bbeta	Protein Coding	1
304	PPP2R2C	Protein Phosphatase 2 Regulatory Subunit Bgamma	Protein Coding	1
305	PPP2R3A	Protein Phosphatase 2 Regulatory Subunit B''''Alpha	Protein Coding	1
306	PTPA	Protein Phosphatase 2 Phosphatase Activator	Protein Coding	1
307	PPP2R5A	Protein Phosphatase 2 Regulatory Subunit B''Alpha	Protein Coding	1
308	PPP2R5B	Protein Phosphatase 2 Regulatory Subunit B''Beta	Protein Coding	1
309	PPP2R5C	Protein Phosphatase 2 Regulatory Subunit B''Gamma	Protein Coding	1
310	PPP2R5E	Protein Phosphatase 2 Regulatory Subunit B''Epsilon	Protein Coding	1
311	PPP2R3B	Protein Phosphatase 2 Regulatory Subunit B''''Beta~Name Same As:- HGNC:9310	Protein Coding	1
312	PSMA1	Proteasome 20S Subunit Alpha 1	Protein Coding	1
313	PSMA2	Proteasome 20S Subunit Alpha 2	Protein Coding	1
314	PSMA3	Proteasome 20S Subunit Alpha 3	Protein Coding	1
315	PSMA4	Proteasome 20S Subunit Alpha 4	Protein Coding	1
316	PSMA5	Proteasome 20S Subunit Alpha 5	Protein Coding	1
317	PSMA6	Proteasome 20S Subunit Alpha 6	Protein Coding	1
318	PSMA7	Proteasome 20S Subunit Alpha 7	Protein Coding	1
319	PSMB1	Proteasome 20S Subunit Beta 1	Protein Coding	1
320	PSMB10	Proteasome 20S Subunit Beta 10	Protein Coding	1
321	PSMB2	Proteasome 20S Subunit Beta 2	Protein Coding	1
322	PSMB3	Proteasome 20S Subunit Beta 3	Protein Coding	1
323	PSMB4	Proteasome 20S Subunit Beta 4	Protein Coding	1
324	PSMB5	Proteasome 20S Subunit Beta 5	Protein Coding	1
325	PSMB6	Proteasome 20S Subunit Beta 6	Protein Coding	1
326	PSMB7	Proteasome 20S Subunit Beta 7	Protein Coding	1
327	PSMB8	Proteasome 20S Subunit Beta 8	Protein Coding	1
328	PSMB9	Proteasome 20S Subunit Beta 9	Protein Coding	1
329	PSMC1	Proteasome 26S Subunit, ATPase 1	Protein Coding	1
330	PSMC2	Proteasome 26S Subunit, ATPase 2	Protein Coding	1
331	PSMC3	Proteasome 26S Subunit, ATPase 3	Protein Coding	1
332	PSMC4	Proteasome 26S Subunit, ATPase 4	Protein Coding	1
333	PSMC5	Proteasome 26S Subunit, ATPase 5	Protein Coding	1
334	PSMC6	Proteasome 26S Subunit, ATPase 6	Protein Coding	1
335	PSMD1	Proteasome 26S Subunit, Non-ATPase 1	Protein Coding	1
336	PSMD2	Proteasome 26S Subunit Ubiquitin Receptor, Non-ATPase 2	Protein Coding	1
337	PSMD3	Proteasome 26S Subunit, Non-ATPase 3	Protein Coding	1
338	PSMD4	Proteasome 26S Subunit Ubiquitin Receptor, Non-ATPase 4	Protein Coding	1
339	PSMD5	Proteasome 26S Subunit, Non-ATPase 5	Protein Coding	1
340	PSMD7	Proteasome 26S Subunit, Non-ATPase 7	Protein Coding	1
341	TCF7	Transcription Factor 7	Protein Coding	1
342	TLE1	TLE Family Member 1, Transcriptional Corepressor	Protein Coding	1
343	TLE2	TLE Family Member 2, Transcriptional Corepressor	Protein Coding	1
344	TLE3	TLE Family Member 3, Transcriptional Corepressor	Protein Coding	1
345	ACTA1	Actin Alpha 1, Skeletal Muscle	Protein Coding	1
346	ACTA2	Actin Alpha 2, Smooth Muscle	Protein Coding	1
347	ACTB	Actin Beta	Protein Coding	1
348	ACTG1	Actin Gamma 1	Protein Coding	1
349	ACTG2	Actin Gamma 2, Smooth Muscle	Protein Coding	1
350	ADCY1	Adenylate Cyclase 1	Protein Coding	1
351	ADCY2	Adenylate Cyclase 2	Protein Coding	1
352	ADCY3	Adenylate Cyclase 3	Protein Coding	1
353	ADCY4	Adenylate Cyclase 4	Protein Coding	1
354	ADCY5	Adenylate Cyclase 5	Protein Coding	1
355	ADCY6	Adenylate Cyclase 6	Protein Coding	1
356	ADCY7	Adenylate Cyclase 7	Protein Coding	1
357	ADCY8	Adenylate Cyclase 8	Protein Coding	1
358	ADCY9	Adenylate Cyclase 9	Protein Coding	1
359	AQP1	Aquaporin 1 (Colton Blood Group)	Protein Coding	1
360	AQP10	Aquaporin 10	Protein Coding	1
361	AQP11	Aquaporin 11	Protein Coding	1
362	AQP12A	Aquaporin 12A	Protein Coding	1
363	AQP12B	Aquaporin 12B	Protein Coding	1
364	AQP2	Aquaporin 2	Protein Coding	1
365	AQP3	Aquaporin 3 (Gill Blood Group)	Protein Coding	1
366	AQP4	Aquaporin 4	Protein Coding	1
367	AQP5	Aquaporin 5	Protein Coding	1
368	AQP6	Aquaporin 6	Protein Coding	1
369	AQP7	Aquaporin 7	Protein Coding	1
370	AQP8	Aquaporin 8	Protein Coding	1
371	AQP9	Aquaporin 9	Protein Coding	1
372	BDKRB1	Bradykinin Receptor B1	Protein Coding	1
373	BDKRB2	Bradykinin Receptor B2	Protein Coding	1
374	CALM1	Calmodulin 1	Protein Coding	1
375	CALM2	Calmodulin 2	Protein Coding	1
376	CALM3	Calmodulin 3	Protein Coding	1
377	CASP3	Caspase 3	Protein Coding	1
378	CASP8	Caspase 8	Protein Coding	1
379	CAV1	Caveolin 1	Protein Coding	1
380	CCNA1	Cyclin A1	Protein Coding	1
381	CCNA2	Cyclin A2	Protein Coding	1
382	CHRNA1	Cholinergic Receptor Nicotinic Alpha 1 Subunit	Protein Coding	1
383	CHRNA10	Cholinergic Receptor Nicotinic Alpha 10 Subunit	Protein Coding	1
384	CHRNA2	Cholinergic Receptor Nicotinic Alpha 2 Subunit	Protein Coding	1
385	CHRNA3	Cholinergic Receptor Nicotinic Alpha 3 Subunit	Protein Coding	1
386	CHRNA4	Cholinergic Receptor Nicotinic Alpha 4 Subunit	Protein Coding	1
387	CHRNA5	Cholinergic Receptor Nicotinic Alpha 5 Subunit	Protein Coding	1
388	CHRNA6	Cholinergic Receptor Nicotinic Alpha 6 Subunit	Protein Coding	1
389	CHRNA7	Cholinergic Receptor Nicotinic Alpha 7 Subunit	Protein Coding	1
390	CHRNA9	Cholinergic Receptor Nicotinic Alpha 9 Subunit	Protein Coding	1
391	CHRNB1	Cholinergic Receptor Nicotinic Beta 1 Subunit	Protein Coding	1
392	CHRNB2	Cholinergic Receptor Nicotinic Beta 2 Subunit	Protein Coding	1
393	CHRNB3	Cholinergic Receptor Nicotinic Beta 3 Subunit	Protein Coding	1
394	CHRNB4	Cholinergic Receptor Nicotinic Beta 4 Subunit	Protein Coding	1
395	CHRND	Cholinergic Receptor Nicotinic Delta Subunit	Protein Coding	1
396	CHRNE	Cholinergic Receptor Nicotinic Epsilon Subunit	Protein Coding	1
397	CHRNG	Cholinergic Receptor Nicotinic Gamma Subunit	Protein Coding	1
398	CNGA1	Cyclic Nucleotide Gated Channel Subunit Alpha 1	Protein Coding	1
399	CNGA3	Cyclic Nucleotide Gated Channel Subunit Alpha 3	Protein Coding	1
400	CNGA4	Cyclic Nucleotide Gated Channel Subunit Alpha 4	Protein Coding	1
401	CNGB1	Cyclic Nucleotide Gated Channel Subunit Beta 1	Protein Coding	1
402	CNGB3	Cyclic Nucleotide Gated Channel Subunit Beta 3	Protein Coding	1
403	DNM2	Dynamin 2	Protein Coding	1
404	S1PR1	Sphingosine-1-Phosphate Receptor 1	Protein Coding	1
405	LPAR1	Lysophosphatidic Acid Receptor 1	Protein Coding	1
406	S1PR3	Sphingosine-1-Phosphate Receptor 3	Protein Coding	1
407	LPAR2	Lysophosphatidic Acid Receptor 2	Protein Coding	1
408	S1PR2	Sphingosine-1-Phosphate Receptor 2	Protein Coding	1
409	S1PR4	Sphingosine-1-Phosphate Receptor 4	Protein Coding	1
410	LPAR3	Lysophosphatidic Acid Receptor 3	Protein Coding	1
411	S1PR5	Sphingosine-1-Phosphate Receptor 5	Protein Coding	1
412	ESR1	Estrogen Receptor 1	Protein Coding	1
413	ESR2	Estrogen Receptor 2	Protein Coding	1
414	GNAI1	G Protein Subunit Alpha I1	Protein Coding	1
415	GNAI2	G Protein Subunit Alpha I2	Protein Coding	1
416	GNAI3	G Protein Subunit Alpha I3	Protein Coding	1
417	GNAS	GNAS Complex Locus	Protein Coding	1
418	GNB1	G Protein Subunit Beta 1	Protein Coding	1
419	GNB2	G Protein Subunit Beta 2	Protein Coding	1
420	GNB3	G Protein Subunit Beta 3	Protein Coding	1
421	GNB4	G Protein Subunit Beta 4	Protein Coding	1
422	GNB5	G Protein Subunit Beta 5	Protein Coding	1
423	GNG2	G Protein Subunit Gamma 2	Protein Coding	1
424	GNG3	G Protein Subunit Gamma 3	Protein Coding	1
425	GNG4	G Protein Subunit Gamma 4	Protein Coding	1
426	GUCY1A2	Guanylate Cyclase 1 Soluble Subunit Alpha 2	Protein Coding	1
427	GUCY1A1	Guanylate Cyclase 1 Soluble Subunit Alpha 1	Protein Coding	1
428	GUCY1B1	Guanylate Cyclase 1 Soluble Subunit Beta 1	Protein Coding	1
429	GUCY2C	Guanylate Cyclase 2C	Protein Coding	1
430	GUCY2D	Guanylate Cyclase 2D, Retinal	Protein Coding	1
431	GUCY2EP	Guanylate Cyclase 2E, Pseudogene	Pseudogene	1
432	GUCY2F	Guanylate Cyclase 2F, Retinal	Protein Coding	1
433	HSP90AA1	Heat Shock Protein 90 Alpha Family Class A Member 1	Protein Coding	1
434	HSPA4	Heat Shock Protein Family A (Hsp70) Member 4	Protein Coding	1
435	ITPR1	Inositol 1,4,5-Trisphosphate Receptor Type 1	Protein Coding	1
436	ITPR2	Inositol 1,4,5-Trisphosphate Receptor Type 2	Protein Coding	1
437	ITPR3	Inositol 1,4,5-Trisphosphate Receptor Type 3	Protein Coding	1
438	NOS3	Nitric Oxide Synthase 3	Protein Coding	1
439	NOSIP	Nitric Oxide Synthase Interacting Protein	Protein Coding	1
440	NOSTRIN	Nitric Oxide Synthase Trafficking	Protein Coding	1
441	NPR1	Natriuretic Peptide Receptor 1	Protein Coding	1
442	NPR2	Natriuretic Peptide Receptor 2	Protein Coding	1
443	PDK1	Pyruvate Dehydrogenase Kinase 1	Protein Coding	1
444	PDK2	Pyruvate Dehydrogenase Kinase 2	Protein Coding	1
445	PDK3	Pyruvate Dehydrogenase Kinase 3	Protein Coding	1
446	PDK4	Pyruvate Dehydrogenase Kinase 4	Protein Coding	1
447	PRKAA1	Protein Kinase AMP-Activated Catalytic Subunit Alpha 1	Protein Coding	1
448	PRKAA2	Protein Kinase AMP-Activated Catalytic Subunit Alpha 2	Protein Coding	1
449	PRKAB1	Protein Kinase AMP-Activated Non-Catalytic Subunit Beta 1	Protein Coding	1
450	PRKAB2	Protein Kinase AMP-Activated Non-Catalytic Subunit Beta 2	Protein Coding	1
451	PRKACA	Protein Kinase CAMP-Activated Catalytic Subunit Alpha	Protein Coding	1
452	PRKACB	Protein Kinase CAMP-Activated Catalytic Subunit Beta	Protein Coding	1
453	PRKACG	Protein Kinase CAMP-Activated Catalytic Subunit Gamma	Protein Coding	1
454	PRKAG1	Protein Kinase AMP-Activated Non-Catalytic Subunit Gamma 1	Protein Coding	1
455	PRKAG2	Protein Kinase AMP-Activated Non-Catalytic Subunit Gamma 2	Protein Coding	1
456	PRKAG3	Protein Kinase AMP-Activated Non-Catalytic Subunit Gamma 3	Protein Coding	1
457	PRKAR1A	Protein Kinase CAMP-Dependent Type I Regulatory Subunit Alpha	Protein Coding	1
458	PRKAR1B	Protein Kinase CAMP-Dependent Type I Regulatory Subunit Beta	Protein Coding	1
459	PRKAR2A	Protein Kinase CAMP-Dependent Type II Regulatory Subunit Alpha	Protein Coding	1
460	PRKAR2B	Protein Kinase CAMP-Dependent Type II Regulatory Subunit Beta	Protein Coding	1
461	PRKG1	Protein Kinase CGMP-Dependent 1	Protein Coding	1
462	SLC7A1	Solute Carrier Family 7 Member 1	Protein Coding	1
463	STUB1	STIP1 Homology And U-Box Containing Protein 1	Protein Coding	1
464	VEGFA	Vascular Endothelial Growth Factor A	Protein Coding	1
465	AKT1S1	AKT1 Substrate 1	Protein Coding	1
466	BAD	BCL2 Associated Agonist Of Cell Death	Protein Coding	1
467	CBL	Cbl Proto-Oncogene	Protein Coding	1
468	CD55	CD55 Molecule (Cromer Blood Group)	Protein Coding	1
469	ELK1	ETS Transcription Factor ELK1	Protein Coding	1
470	FOS	Fos Proto-Oncogene, AP-1 Transcription Factor Subunit	Protein Coding	1
471	JUN	Jun Proto-Oncogene, AP-1 Transcription Factor Subunit	Protein Coding	1
472	MAP2K3	Mitogen-Activated Protein Kinase Kinase 3	Protein Coding	1
473	MAP2K4	Mitogen-Activated Protein Kinase Kinase 4	Protein Coding	1
474	MAP2K5	Mitogen-Activated Protein Kinase Kinase 5	Protein Coding	1
475	MAP2K6	Mitogen-Activated Protein Kinase Kinase 6	Protein Coding	1
476	MAP3K5	Mitogen-Activated Protein Kinase Kinase Kinase 5	Protein Coding	1
477	MAPT	Microtubule Associated Protein Tau	Protein Coding	1
478	PLCB1	Phospholipase C Beta 1	Protein Coding	1
479	PLCB2	Phospholipase C Beta 2	Protein Coding	1
480	PLCB3	Phospholipase C Beta 3	Protein Coding	1
481	PLCB4	Phospholipase C Beta 4	Protein Coding	1
482	PLCD1	Phospholipase C Delta 1	Protein Coding	1
483	PLCD3	Phospholipase C Delta 3	Protein Coding	1
484	PLCD4	Phospholipase C Delta 4	Protein Coding	1
485	PLCE1	Phospholipase C Epsilon 1	Protein Coding	1
486	PLCZ1	Phospholipase C Zeta 1	Protein Coding	1
487	PRKCA	Protein Kinase C Alpha	Protein Coding	1
488	PRKCB	Protein Kinase C Beta	Protein Coding	1
489	PRKCD	Protein Kinase C Delta	Protein Coding	1
490	PRKCE	Protein Kinase C Epsilon	Protein Coding	1
491	PRKCG	Protein Kinase C Gamma	Protein Coding	1
492	PRKCH	Protein Kinase C Eta	Protein Coding	1
493	PRKCI	Protein Kinase C Iota	Protein Coding	1
494	PRKD1	Protein Kinase D1	Protein Coding	1
495	PRKD3	Protein Kinase D3	Protein Coding	1
496	PRKCQ	Protein Kinase C Theta	Protein Coding	1
497	PRKCZ	Protein Kinase C Zeta	Protein Coding	1
498	RPS6KA2	Ribosomal Protein S6 Kinase A2	Protein Coding	1
499	RPS6KA4	Ribosomal Protein S6 Kinase A4	Protein Coding	1
500	RPS6KA5	Ribosomal Protein S6 Kinase A5	Protein Coding	1
501	RPS6KA6	Ribosomal Protein S6 Kinase A6	Protein Coding	1
502	RPS6KB1	Ribosomal Protein S6 Kinase B1	Protein Coding	1
503	RPS6KB2	Ribosomal Protein S6 Kinase B2	Protein Coding	1
504	RPS6KC1	Ribosomal Protein S6 Kinase C1	Protein Coding	1
505	SNCA	Synuclein Alpha	Protein Coding	1
506	SRC	SRC Proto-Oncogene, Non-Receptor Tyrosine Kinase	Protein Coding	1
507	TNF	Tumor Necrosis Factor	Protein Coding	1
508	TNFRSF1A	TNF Receptor Superfamily Member 1A	Protein Coding	1
509	TP73	Tumor Protein P73	Protein Coding	1
510	TRAF2	TNF Receptor Associated Factor 2	Protein Coding	1
511	TSC1	TSC Complex Subunit 1	Protein Coding	1
512	TSC2	TSC Complex Subunit 2	Protein Coding	1
513	TUBA4A	Tubulin Alpha 4a	Protein Coding	1
514	TUBA3C	Tubulin Alpha 3c	Protein Coding	1
515	TUBA8	Tubulin Alpha 8	Protein Coding	1
516	TUBB1	Tubulin Beta 1 Class VI	Protein Coding	1
517	TUBB2A	Tubulin Beta 2A Class IIa	Protein Coding	1
518	TUBB7P	Tubulin Beta 7 Pseudogene	Pseudogene	1
519	TUBE1	Tubulin Epsilon 1	Protein Coding	1
520	TUBG1	Tubulin Gamma 1	Protein Coding	1
521	TUBG2	Tubulin Gamma 2	Protein Coding	1
522	TUBGCP2	Tubulin Gamma Complex Component 2	Protein Coding	1
523	TUBGCP3	Tubulin Gamma Complex Component 3	Protein Coding	1
524	TUBGCP5	Tubulin Gamma Complex Component 5	Protein Coding	1
525	TUBGCP6	Tubulin Gamma Complex Component 6	Protein Coding	1
526	VIM	Vimentin	Protein Coding	1
527	YAP1	Yes1 Associated Transcriptional Regulator	Protein Coding	1
528	YWHAB	Tyrosine 3-Monooxygenase/Tryptophan 5-Monooxygenase Activation Protein Beta	Protein Coding	1
529	YWHAE	Tyrosine 3-Monooxygenase/Tryptophan 5-Monooxygenase Activation Protein Epsilon	Protein Coding	1
530	YWHAG	Tyrosine 3-Monooxygenase/Tryptophan 5-Monooxygenase Activation Protein Gamma	Protein Coding	1
531	YWHAH	Tyrosine 3-Monooxygenase/Tryptophan 5-Monooxygenase Activation Protein Eta	Protein Coding	1
532	YWHAQ	Tyrosine 3-Monooxygenase/Tryptophan 5-Monooxygenase Activation Protein Theta	Protein Coding	1
533	YWHAZ	Tyrosine 3-Monooxygenase/Tryptophan 5-Monooxygenase Activation Protein Zeta	Protein Coding	1

Disorders associated with Nanog in Mammalian ESC Pluripotency SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Rasopathy	Enrichment	BRAF, HRAS, KRAS, MAP2K1, MAP2K2, MRAS, NRAS, RAF1, RRAS2, SOS1, SOS2	11.29
2	Noonan syndrome 1	Enrichment	BRAF, HRAS, KRAS, MAP2K1, MAP2K2, MRAS, NRAS, RAF1, RRAS, RRAS2, SOS1, SOS2	10.56
3	Noonan syndrome and noonan-related syndrome	Enrichment	BRAF, HRAS, KRAS, MAP2K1, MAP2K2, NRAS, RAF1, SOS1	10.29
4	Lung non-small cell carcinoma	Enrichment	BRAF, EGFR, ERBB2, HRAS, KRAS, MAP2K1, NRAS	10.06
5	Pilomyxoid astrocytoma	Enrichment	BRAF, FGFR1, KRAS, NTRK2, RAF1	7.64
6	Lung cancer susceptibility 3	Enrichment	BRAF, EGFR, ERBB2, FGF10, KRAS, ROS1	7.32
7	Melanocytic nevus syndrome, congenital	Enrichment	ALK, BRAF, HRAS, NRAS, RAF1	7.22
8	Cardiofaciocutaneous syndrome 1	Enrichment	BRAF, KRAS, MAP2K1, MAP2K2	7.16
9	Cardiofaciocutaneous syndrome	Enrichment	BRAF, KRAS, MAP2K1, MAP2K2	7.16
10	Leukoencephalopathy with vanishing white matter 1	Enrichment	EIF2B1, EIF2B2, EIF2B3, EIF2B4, EIF2B5	6.78
11	Bladder cancer	Enrichment	CTNNB1, EGFR, ERBB2, ERBB3, FGFR3, HRAS, KRAS	6.48
12	Differentiated thyroid carcinoma	Enrichment	ALK, BRAF, HRAS, KRAS, NRAS, NTRK1, NTRK3	6.48
13	Robinow syndrome, autosomal recessive 1	Enrichment	DVL1, FZD2, ROR2, WNT5A	6.46
14	Leukoencephalopathy with vanishing white matter 5	Enrichment	EIF2B1, EIF2B2, EIF2B3, EIF2B4, EIF2B5	6.36
15	Ovarian cancer	Enrichment	ALK, APC, CTNNB1, EGFR, ERBB2, KIT, KRAS, MET, NTRK1, PDGFRA, RRAS2	6.11
16	Leukoencephalopathy with vanishing white matter	Enrichment	EIF2B1, EIF2B2, EIF2B3, EIF2B4, EIF2B5	6.02
17	Autosomal recessive robinow syndrome	Enrichment	DVL1, FZD2, ROR2, WNT5A	5.99
18	Lung squamous cell carcinoma	Enrichment	ALK, EGFR, FGFR3, KRAS	5.99
19	Colorectal cancer	Enrichment	AKT1, APC, CDH1, CTNNB1, ERBB2, FGFR2, FGFR3, FZD3, IGF2, MET, NRAS, PIK3R1	5.92
20	Nevus, epidermal	Enrichment	FGFR3, HRAS, KRAS, NRAS	5.63
21	Noonan syndrome 3	Enrichment	HRAS, KRAS, RAF1, SOS1	5.63
22	Postsynaptic congenital myasthenic syndromes	Enrichment	CHRNA1, CHRNB1, CHRND, CHRNE, MUSK	5.48
23	Lacrimoauriculodentodigital syndrome 1	Enrichment	FGF10, FGFR2, FGFR3	5.36
24	Langerhans cell histiocytosis	Enrichment	BRAF, MAP2K1, NRAS	5.36
25	Myasthenic syndrome, congenital, 1a, slow-channel	Enrichment	CHRNA1, CHRNB1, CHRND, CHRNE	5.13
26	Hamartoma	Enrichment	FGFR3, TSC1, TSC2	5.11
27	Arteriovenous malformation	Enrichment	EPHB4, HRAS, MAP2K1, TEK	5.08
28	Arteriovenous malformations of the brain	Enrichment	BRAF, EGFR, IL6, KRAS, TIMP3	4.97
29	Lung cancer	Enrichment	ALK, BRAF, EGFR, ERBB2, KRAS, MET	4.94
30	Myopathy, x-linked, with excessive autophagy	Enrichment	EPHB4, HRAS, MAP2K1, TEK	4.87
31	Schimmelpenning-feuerstein-mims syndrome	Enrichment	HRAS, KRAS, NRAS	4.77
32	Robinow syndrome, autosomal dominant 1	Enrichment	DVL1, FZD2, WNT5A	4.77
33	Craniopharyngioma	Enrichment	APC, BRAF, CTNNB1	4.77
34	Autosomal dominant robinow syndrome	Enrichment	DVL1, FZD2, WNT5A	4.77
35	Lip and oral cavity carcinoma	Enrichment	BRAF, EGFR, HRAS, KIT	4.51
36	Myasthenic syndrome, congenital, 1b, fast-channel	Enrichment	CHRNA1, CHRND, CHRNE	4.39
37	Primary hypereosinophilic syndrome	Enrichment	FGFR1, PDGFRA, PDGFRB	4.37
38	Juvenile myelomonocytic leukemia	Enrichment	CBL, KRAS, NRAS, RRAS	4.18
39	Testicular germ cell tumor	Enrichment	FGFR3, KIT, KITLG	4.08
40	Microform holoprosencephaly	Enrichment	CRIPTO, FGF8, FGFR1, GAS1	3.96
41	Lobar holoprosencephaly	Enrichment	CRIPTO, FGF8, FGFR1, GAS1	3.96
42	Non-immune hydrops fetalis	Enrichment	EPHB4, FLT4, FZD6, HRAS, KRAS	3.87
43	Giant cell glioblastoma	Enrichment	EGFR, FGFR1, FGFR3, ROS1	3.85
44	Thyroid cancer, nonmedullary, 2	Enrichment	BRAF, HRAS, NRAS	3.84
45	Capillary malformation-arteriovenous malformation 1	Enrichment	EPHB4, KRAS, MAP2K1	3.84
46	Gallbladder cancer	Enrichment	BRAF, CTNNB1, KRAS	3.84
47	Follicular thyroid carcinoma	Enrichment	BRAF, HRAS, NRAS	3.84
48	Semilobar holoprosencephaly	Enrichment	CRIPTO, FGF8, FGFR1, GAS1	3.75
49	Normosmic congenital hypogonadotropic hypogonadism	Enrichment	FGF17, FGF8, FGFR1, GNRH1	3.75
50	Lymphatic malformation 1	Enrichment	EPHB4, FLT4	3.57
51	Intracranial hypertension, idiopathic	Enrichment	EPHB4, FLT4	3.57
52	Pulmonic stenosis	Enrichment	BRAF, SOS1	3.57
53	Pfeiffer syndrome	Enrichment	FGFR1, FGFR2	3.57
54	Jackson-weiss syndrome	Enrichment	FGFR1, FGFR2	3.57
55	Encephalocraniocutaneous lipomatosis	Enrichment	FGFR1, KRAS	3.57
56	Ras-associated autoimmune leukoproliferative disorder	Enrichment	KRAS, NRAS	3.57
57	Childhood hepatocellular carcinoma	Enrichment	CTNNB1, MET	3.57
58	Loeys-dietz syndrome 4	Enrichment	TGFB2, TGFB3	3.57
59	Hereditary lymphedema i	Enrichment	EPHB4, FLT4	3.57
60	Autosomal dominant sleep-related hypermotor epilepsy	Enrichment	CHRNA2, CHRNA4, CHRNB2	3.47
61	Adult hepatocellular carcinoma	Enrichment	AXIN1, CTNNB1, EGF	3.47
62	Lymphangioleiomyomatosis	Enrichment	TSC1, TSC2	3.41
63	Hepatocellular carcinoma	Enrichment	APC, AXIN1, CTNNB1, MET	3.39
64	Tooth agenesis	Enrichment	FGFR1, TGFA, WNT10A, WNT10B	3.39
65	Pigmented nodular adrenocortical disease, primary, 1	Enrichment	GNAS, PRKAR1A	3.32
66	Achromatopsia 3	Enrichment	CNGA3, CNGB3	3.32
67	Smoking as a quantitative trait locus 3	Enrichment	CHRNA3, CHRNA5	3.32
68	Baraitser-winter cerebrofrontofacial syndrome	Enrichment	ACTB, ACTG1	3.32
69	Kallmann syndrome	Enrichment	FGF17, FGF8, FGFR1, SEMA3A	3.32
70	Multiple pterygium syndrome, lethal type	Enrichment	CHRNA1, CHRND, CHRNG	3.27
71	Catecholaminergic polymorphic ventricular tachycardia	Enrichment	CALM1, CALM2, CALM3	3.27
72	Proteasome-associated autoinflammatory syndrome 3	Enrichment	PSMB4, PSMB9	3.23
73	Split hand-foot malformation	Enrichment	FGFR2, LEF1	3.23
74	Hydrops fetalis, nonimmune	Enrichment	EPHB4, FLT4, FZD6, HRAS	3.10
75	Crouzon syndrome	Enrichment	FGFR2, FGFR3	3.10
76	Desmoid disease, hereditary	Enrichment	APC, CTNNB1	3.10
77	Osteoporosis, juvenile	Enrichment	WNT1, WNT3A	3.10
78	Large congenital melanocytic nevus	Enrichment	HRAS, NRAS	3.10
79	Desmoid tumor	Enrichment	APC, CTNNB1	3.10
80	Testicular germ cell cancer	Enrichment	FGFR3, KIT	3.10
81	Spermatocytoma	Enrichment	FGFR3, HRAS	3.10
82	Myeloma, multiple	Enrichment	FGFR3, FLT3, KRAS, MST1R, PIK3R2, YAP1	3.09
83	Centronuclear myopathy	Enrichment	ACTA1, CHRNA1, CHRND, DNM2	3.00
84	Nk-cell enteropathy	Enrichment	AXL, ERBB4, IGF1R	2.96
85	Specific learning disability	Enrichment	MAPK1, RPS6KA3, YWHAG	2.95
86	Tuberous sclerosis 1	Enrichment	TSC1, TSC2	2.94
87	Fetal akinesia deformation sequence 1	Enrichment	ACTA1, CHRND, CHRNG, MUSK, ROR2	2.93
88	Thyroid carcinoma, familial medullary	Enrichment	ESR2, NTRK1	2.85
89	Epilepsy, nocturnal frontal lobe, 1	Enrichment	CHRNA4, CHRNB2	2.85
90	Frontotemporal dementia 1	Enrichment	CHRNA4, CHRNB4, CSF1R	2.83
91	Brachydactyly, type a2	Enrichment	BMP2, GDF5	2.81
92	Glaucoma 3, primary infantile, b	Enrichment	LTBP2, TEK	2.81
93	Saethre-chotzen syndrome	Enrichment	FGFR2, FGFR3	2.81
94	Multiple synostoses syndrome	Enrichment	GDF5, GDF6	2.81
95	Chronic myelogenous leukemia, bcr-abl1 positive	Enrichment	KRAS, NRAS	2.81
96	Noonan syndrome with multiple lentigines	Enrichment	BRAF, RAF1	2.81
97	Acute myeloid leukemia with abnormal bone marrow eosinophils inv(16)(p13q22) or t(16;16)(p13;q22)	Enrichment	FLT3, KIT	2.81
98	Glioma	Enrichment	FGFR2, NTRK3	2.81
99	Hydrocephalus	Enrichment	FGFR2, FZD3, PDGFRB	2.77
100	Septopreoptic holoprosencephaly	Enrichment	CRIPTO, FGF8, GAS1	2.77
101	Midline interhemispheric variant of holoprosencephaly	Enrichment	CRIPTO, FGF8, GAS1	2.77
102	Proteasome-associated autoinflammatory syndrome 1	Enrichment	PSMB4, PSMB8	2.76
103	Proteosome-associated autoinflammatory syndrome	Enrichment	PSMB4, PSMB8	2.76
104	Alzheimer's disease	Enrichment	CSF1R, MAPT, TNF	2.72
105	Gliosarcoma	Enrichment	EGFR, FGFR1, FGFR3	2.68
106	Focal cortical dysplasia, type ii	Enrichment	TSC1, TSC2	2.64
107	Tuberous sclerosis	Enrichment	TSC1, TSC2	2.64
108	Noonan syndrome-like disorder with or without juvenile myelomonocytic leukemia	Enrichment	CBL, YWHAZ	2.64
109	Isolated focal cortical dysplasia type ii	Enrichment	TSC1, TSC2	2.64
110	Alobar holoprosencephaly	Enrichment	CRIPTO, FGF8, GAS1	2.61
111	Hemifacial hyperplasia	Enrichment	FGFR2, FGFR3	2.59
112	Exudative vitreoretinopathy 1	Enrichment	CTNNB1, FZD4	2.59
113	Insulin-like growth factor i	Enrichment	IGF1, IGF1R	2.59
114	Ventricular septal defect 1	Enrichment	BMP2, BMP7	2.59
115	Robinow syndrome, autosomal dominant 2	Enrichment	DVL1, FZD2	2.59
116	Acute myeloid leukemia with maturation	Enrichment	FLT3, KIT	2.59
117	Holoprosencephaly	Enrichment	FGF8, FGFR1	2.59
118	Acute myeloid leukemia with t(8;21)(q22;q22) translocation	Enrichment	FLT3, KIT	2.59
119	Autosomal dominant nocturnal frontal lobe epilepsy	Enrichment	CHRNA4, CHRNB2	2.56
120	Diffuse gastric and lobular breast cancer syndrome	Enrichment	CDH1, KRAS	2.47
121	Rhabdomyosarcoma	Enrichment	ALK, CBL, HRAS	2.45
122	Gastric cancer	Enrichment	APC, CDH1, ERBB2, FGFR2, KRAS	2.43
123	Histiocytoid hemangioma	Enrichment	FOS, VIM	2.42
124	Atrial septal defect 1	Enrichment	BMP2, TGFB2	2.42
125	Holoprosencephaly 1	Enrichment	FGF8, FGFR1	2.42
126	Hemangioma, capillary infantile	Enrichment	FLT4, KDR	2.42
127	46,xy disorder of sex development	Enrichment	FGFR3, INSR	2.42
128	Long qt syndrome 1	Enrichment	CALM1, CALM2, CALM3, ITPR3	2.41
129	Macs syndrome	Enrichment	GDF6, SOX2, WNT7B	2.40
130	Leukemia, acute myeloid	Enrichment	FLT3, KIT, KRAS, NRAS	2.40
131	Cleft lip/palate	Enrichment	BMP4, CDH1, PDGFRA	2.37
132	Pre-eclampsia	Enrichment	FLT1, NOS3	2.34
133	Diffuse cutaneous systemic sclerosis	Enrichment	CAV1, CCN2	2.34
134	Hepatoblastoma	Enrichment	APC, CTNNB1, FGFR3	2.33
135	Glaucoma 3, primary congenital, a	Enrichment	LTBP2, TEK	2.28
136	Gastrointestinal stromal tumor	Enrichment	KIT, PDGFRA	2.28
137	Leukemia, chronic myeloid	Enrichment	KRAS, NRAS	2.28
138	Neuropathy, hereditary sensory and autonomic, type v	Enrichment	NGF, NTRK1	2.28
139	Breast adenocarcinoma	Enrichment	AKT1, KRAS	2.25
140	Moyamoya disease 1	Enrichment	ACTA2, GUCY1A1	2.17
141	Spinocerebellar ataxia, autosomal recessive 16	Enrichment	ITPR1, STUB1	2.17
142	Limited scleroderma	Enrichment	CAV1, CCN2	2.17
143	Basal ganglia calcification, idiopathic, 1	Enrichment	PDGFB, PDGFRB	2.16
144	Hemochromatosis, type 1	Enrichment	BMP2, BMP6	2.16
145	Exudative vitreoretinopathy	Enrichment	CTNNB1, FZD4	2.16
146	Split-hand/foot malformation 1	Enrichment	FGFR2, LEF1	2.08
147	Tetralogy of fallot	Enrichment	EPHB4, FLT4, KDR	2.07
148	Frontotemporal dementia and/or amyotrophic lateral sclerosis 7	Enrichment	CHRNA3, CHRNA4, CHRNB4, CSF1R, ERBB4	2.07
149	Loeys-dietz syndrome	Enrichment	TGFB2, TGFB3	2.05
150	Ventricular septal defect	Enrichment	BRAF, TEK	2.05
151	Renal agenesis, bilateral	Enrichment	FGF20, WNT9B	2.05
152	Craniosynostosis	Enrichment	FGFR2, FGFR3, NPR2	2.05
153	Marfan syndrome	Enrichment	LTBP2, TGFB2	1.96
154	Hirschsprung disease 1	Enrichment	ERBB2, ERBB3, NRG3	1.94
155	Inflammatory bowel disease 1	Enrichment	IL6, PRKCQ	1.89
156	Distal arthrogryposis	Enrichment	ACTA1, CHRND, CHRNG, ROR2	1.89
157	Isolated split hand-split foot malformation	Enrichment	BTRC, WNT10B	1.82
158	Familial thoracic aortic aneurysm and aortic dissection	Enrichment	ACTA2, PRKG1, TGFB2, TGFB3	1.82
159	Ellis-van creveld syndrome	Enrichment	PRKACA, PRKACB	1.81
160	Septooptic dysplasia	Enrichment	FGFR1, SOX2	1.80
161	Renal hypodysplasia/aplasia 3	Enrichment	BMP4, FGFR3	1.80
162	Autosomal dominant macrothrombocytopenia	Enrichment	TUBA8, TUBB1	1.80
163	Inherited cancer-predisposing syndrome	Enrichment	ALK, EGFR, KIT, MET, PDGFRA, TSC1, TSC2	1.79
164	Lymphatic malformation 5	Enrichment	EPHB4	1.79
165	Brachydactyly, type b1	Enrichment	ROR2	1.79
166	Erythroleukemia, familial	Enrichment	ERBB3	1.79
167	Hypochondroplasia	Enrichment	FGFR3	1.79
168	Beare-stevenson cutis gyrata syndrome	Enrichment	FGFR2	1.79
169	Paget disease, extramammary	Enrichment	ERBB2	1.79
170	Osteoglophonic dysplasia	Enrichment	FGFR1	1.79
171	Nail disorder, nonsyndromic congenital, 1	Enrichment	FZD6	1.79
172	Mullerian aplasia and hyperandrogenism	Enrichment	WNT4	1.79
173	Thanatophoric dysplasia, type i	Enrichment	FGFR3	1.79
174	Microspherophakia and/or megalocornea, with ectopia lentis and with or without secondary glaucoma	Enrichment	LTBP2	1.79
175	Trigonocephaly 1	Enrichment	FGFR1	1.79
176	Donohue syndrome	Enrichment	INSR	1.79
177	Spinocerebellar ataxia 27a	Enrichment	FGF14	1.79
178	Oculoectodermal syndrome	Enrichment	KRAS	1.79
179	Muenke syndrome	Enrichment	FGFR3	1.79
180	Pallister-killian syndrome	Enrichment	ARAF	1.79
181	Premature aging syndrome, penttinen type	Enrichment	PDGFRB	1.79
182	Hyperinsulinemic hypoglycemia, familial, 5	Enrichment	INSR	1.79
183	Noonan syndrome 5	Enrichment	RAF1	1.79
184	Pineal hyperplasia, insulin-resistant diabetes mellitus, and somatic abnormalities	Enrichment	INSR	1.79
185	Hypomagnesemia 4, renal	Enrichment	EGF	1.79
186	Glaucoma 3, primary congenital, d	Enrichment	LTBP2	1.79
187	Diabetes mellitus, insulin-resistant, with acanthosis nigricans	Enrichment	INSR	1.79
188	Microphthalmia, isolated 4	Enrichment	GDF6	1.79
189	Angel-shaped phalangoepiphyseal dysplasia	Enrichment	GDF5	1.79
190	Noonan syndrome 4	Enrichment	SOS1	1.79
191	Hypereosinophilic syndrome, idiopathic	Enrichment	PDGFRA	1.79
192	46,xx sex reversal with dysgenesis of kidneys, adrenals, and lungs	Enrichment	WNT4	1.79
193	Deafness, autosomal recessive 39	Enrichment	HGF	1.79
194	Mastocytosis, cutaneous	Enrichment	KIT	1.79
195	Scaphocephaly, maxillary retrusion, and impaired intellectual development	Enrichment	FGFR2	1.79
196	Melorheostosis, isolated	Enrichment	MAP2K1	1.79
197	Omodysplasia 2	Enrichment	FZD2	1.79
198	Noonan syndrome 7	Enrichment	BRAF	1.79
199	Leopard syndrome 3	Enrichment	BRAF	1.79
200	Apert syndrome	Enrichment	FGFR2	1.79
201	Neuroblastoma 3	Enrichment	ALK	1.79
202	Basal ganglia calcification, idiopathic, 5	Enrichment	PDGFB	1.79
203	Hyperpigmentation with or without hypopigmentation, familial progressive	Enrichment	KITLG	1.79
204	Cardiomyopathy, dilated, 1nn	Enrichment	RAF1	1.79
205	Cardiofaciocutaneous syndrome 3	Enrichment	MAP2K1	1.79
206	Split-hand/foot malformation 6	Enrichment	WNT10B	1.79
207	Myofibromatosis, infantile, 1	Enrichment	PDGFRB	1.79
208	Melanosis, neurocutaneous	Enrichment	NRAS	1.79
209	Thanatophoric dysplasia, type ii	Enrichment	FGFR3	1.79
210	Noonan syndrome 9	Enrichment	SOS2	1.79
211	Lethal congenital contracture syndrome 2	Enrichment	ERBB3	1.79
212	Caudal duplication anomaly	Enrichment	AXIN1	1.79
213	Noonan syndrome 6	Enrichment	NRAS	1.79
214	Hypogonadotropic hypogonadism 20 with or without anosmia	Enrichment	FGF17	1.79
215	Tooth agenesis, selective, 8	Enrichment	WNT10B	1.79
216	Ciliary dyskinesia, primary, 33	Enrichment	DRC4	1.79
217	Gist-plus syndrome	Enrichment	PDGFRA	1.79
218	Camptodactyly, tall stature, and hearing loss syndrome	Enrichment	FGFR3	1.79
219	Hypogonadotropic hypogonadism 23 with or without anosmia	Enrichment	LHB	1.79
220	Aplasia of lacrimal and salivary glands	Enrichment	FGF10	1.79
221	Bent bone dysplasia syndrome 1	Enrichment	FGFR2	1.79
222	Weill-marchesani syndrome 3	Enrichment	LTBP2	1.79
223	Noonan syndrome 11	Enrichment	MRAS	1.79
224	Visceral neuropathy, familial, 2, autosomal recessive	Enrichment	ERBB2	1.79
225	Noonan syndrome 13	Enrichment	MAPK1	1.79
226	Deafness, autosomal recessive 108	Enrichment	ROR1	1.79
227	Myasthenic syndrome, congenital, 9, associated with acetylcholine receptor deficiency	Enrichment	MUSK	1.79
228	Developmental and epileptic encephalopathy 58	Enrichment	NTRK2	1.79
229	Multiple synostoses syndrome 4	Enrichment	GDF6	1.79
230	Intellectual developmental disorder, x-linked 110	Enrichment	FGF13	1.79
231	Spinocerebellar ataxia 27b, late-onset	Enrichment	FGF14	1.79
232	Venous malformations, multiple cutaneous and mucosal	Enrichment	TEK	1.79
233	Hyperemesis gravidarum	Enrichment	GDF15	1.79
234	Amegakaryocytic thrombocytopenia, congenital, 2	Enrichment	THPO	1.79
235	Deafness, autosomal recessive 125	Enrichment	GAS2	1.79
236	Hereditary lymphedema id	Enrichment	VEGFC	1.79
237	Osteofibrous dysplasia	Enrichment	MET	1.79
238	Diarrhea 9	Enrichment	WNT2B	1.79
239	Microphthalmia, syndromic 6	Enrichment	BMP4	1.79
240	Spondylometaepiphyseal dysplasia, short limb-hand type	Enrichment	DDR2	1.79
241	Myeloid and lymphoid neoplasms associated with pdgfra rearrangement	Enrichment	PDGFRA	1.79
242	Developmental and epileptic encephalopathy 90	Enrichment	FGF13	1.79
243	Orofacial cleft 11	Enrichment	BMP4	1.79
244	Metacarpal 4-5 fusion	Enrichment	FGF16	1.79
245	Lymphatic malformation 4	Enrichment	VEGFC	1.79
246	Lacrimoauriculodentodigital syndrome 3	Enrichment	FGF10	1.79
247	Familial isolated trichomegaly	Enrichment	FGF5	1.79
248	Bone mineral density quantitative trait locus 16	Enrichment	WNT1	1.79
249	Cardiofaciocutaneous syndrome 2	Enrichment	KRAS	1.79
250	Deafness, autosomal recessive 97	Enrichment	MET	1.79
251	Prostate cancer/brain cancer susceptibility	Enrichment	EPHB2	1.79
252	Lymphangioma	Enrichment	BRAF	1.79
253	Skin/hair/eye pigmentation, variation in, 7	Enrichment	KITLG	1.79
254	Crouzon syndrome with acanthosis nigricans	Enrichment	FGFR3	1.79
255	Camurati-engelmann disease 2	Enrichment	TGFB2	1.79
256	Geleophysic dysplasia 3	Enrichment	LTBP3	1.79
257	Phace association	Enrichment	BRAF	1.79
258	Santos syndrome	Enrichment	WNT7A	1.79
259	Melorheostosis	Enrichment	MAP2K1	1.79
260	Autism 9	Enrichment	MET	1.79
261	Leopard syndrome 2	Enrichment	RAF1	1.79
262	Glaucoma 1, open angle, o	Enrichment	NTF4	1.79
263	Iron overload	Enrichment	BMP6	1.79
264	Basal ganglia calcification, idiopathic, 4	Enrichment	PDGFRB	1.79
265	Hypogonadotropic hypogonadism 12 with or without anosmia	Enrichment	GNRH1	1.79
266	Cardiofaciocutaneous syndrome 4	Enrichment	MAP2K2	1.79
267	Hypogonadotropic hypogonadism 16 with or without anosmia	Enrichment	SEMA3A	1.79
268	Leber congenital amaurosis 17	Enrichment	GDF6	1.79
269	Telangiectasia, hereditary hemorrhagic, type 5	Enrichment	GDF2	1.79
270	Amyotrophic lateral sclerosis 19	Enrichment	ERBB4	1.79
271	Hereditary thrombocytosis with transverse limb defect	Enrichment	THPO	1.79
272	Nasopharyngeal carcinoma 3	Enrichment	MST1R	1.79
273	Myeloid and lymphoid neoplasms associated with pdgfrb rearrangement	Enrichment	PDGFRB	1.79
274	Acute myeloid leukemia with minimal differentiation	Enrichment	FLT3	1.79
275	Microphthalmia/coloboma 11	Enrichment	FZD5	1.79
276	Hypogonadotropic hypogonadism 6 with or without anosmia	Enrichment	FGF8	1.79
277	Obesity, hyperphagia, and developmental delay	Enrichment	NTRK2	1.79
278	Achondroplasia, severe, with developmental delay and acanthosis nigricans	Enrichment	FGFR3	1.79
279	Kosaki overgrowth syndrome	Enrichment	PDGFRB	1.79
280	Tumoral calcinosis, hyperphosphatemic, familial, 2	Enrichment	FGF23	1.79
281	Hartsfield syndrome	Enrichment	FGFR1	1.79
282	Congenital heart defects, multiple types, 7	Enrichment	FLT4	1.79
283	Loeys-dietz syndrome 5	Enrichment	TGFB3	1.79
284	Renal hypodysplasia/aplasia 2	Enrichment	FGF20	1.79
285	Bleeding disorder, platelet-type, 22	Enrichment	EPHB2	1.79
286	20p12.3 microdeletion syndrome	Enrichment	BMP2	1.79
287	Cutis laxa, autosomal recessive, type iie	Enrichment	LTBP1	1.79
288	Glaucoma 3, primary congenital, e	Enrichment	TEK	1.79
289	Short stature, facial dysmorphism, and skeletal anomalies with or without cardiac anomalies 1	Enrichment	BMP2	1.79
290	Brain abnormalities, neurodegeneration, and dysosteosclerosis	Enrichment	CSF1R	1.79
291	Developmental and epileptic encephalopathy 47	Enrichment	FGF12	1.79
292	Ocular pterygium-digital keloid dysplasia syndrome	Enrichment	PDGFRB	1.79
293	Chronic mast cell leukemia	Enrichment	KIT	1.79
294	Premature ovarian failure 14	Enrichment	GDF9	1.79
295	Trigonitis	Enrichment	RAF1	1.79
296	Warburg-cinotti syndrome	Enrichment	DDR2	1.79
297	Tufted angioma of skin	Enrichment	KDR	1.79
298	Craniometadiaphyseal osteosclerosis with hip dysplasia	Enrichment	AXIN1	1.79
299	Deafness, autosomal dominant 69	Enrichment	KITLG	1.79
300	Thrombocytopenia 9	Enrichment	THPO	1.79
301	Adenoid ameloblastoma	Enrichment	CTNNB1	1.79
302	Arthrogryposis, distal, type 11	Enrichment	MET	1.79
303	Lacrimoauriculodentodigital syndrome 2	Enrichment	FGFR3	1.79
304	Csf1r-related disorder	Enrichment	CSF1R	1.79
305	Short-rib thoracic dysplasia 22 without polydactyly	Enrichment	FGF4	1.79
306	Bockenheimer syndrome	Enrichment	TEK	1.79
307	Glaucoma secondary to spherophakia/ectopia lentis and megalocornea	Enrichment	LTBP2	1.79
308	Isolated bone marrow mastocytosis	Enrichment	KIT	1.79
309	Congenital pulmonary airway malformation	Enrichment	KRAS	1.79
310	Smoldering systemic mastocytosis	Enrichment	KIT	1.79
311	Alk-positive anaplastic large cell lymphoma	Enrichment	ALK	1.79
312	Familial adenomatous polyposis	Enrichment	APC	1.79
313	Spinocerebellar ataxia type 27b	Enrichment	FGF14	1.79
314	Fgfr3-related chondrodysplasia	Enrichment	FGFR3	1.79
315	Mastocytosis	Enrichment	KIT	1.79
316	Congenital primary lymphedema of gordon	Enrichment	VEGFC	1.79
317	Syringocystadenoma papilliferum	Enrichment	BRAF	1.79
318	Camptodactyly-tall stature-scoliosis-hearing loss syndrome	Enrichment	FGFR3	1.79
319	Familial progressive hyperpigmentation	Enrichment	KITLG	1.79
320	Early-onset calcifying leukoencephalopathy-skeletal dysplasia	Enrichment	CSF1R	1.79
321	Ganglioglioma	Enrichment	BRAF	1.79
322	Cutaneous mastocytoma	Enrichment	KIT	1.79
323	Nongerminomatous germ cell tumor	Enrichment	BRAF	1.79
324	Phace syndrome	Enrichment	BRAF	1.79
325	Gardner syndrome	Enrichment	APC	1.79
326	Typical urticaria pigmentosa	Enrichment	KIT	1.79
327	5q22 microdeletion syndrome	Enrichment	APC	1.79
328	Phakomatosis pigmentokeratotica	Enrichment	HRAS	1.79
329	Attenuated familial adenomatous polyposis	Enrichment	APC	1.79
330	Classic hairy cell leukemia	Enrichment	BRAF	1.79
331	Nodular urticaria pigmentosa	Enrichment	KIT	1.79
332	Hartsfield-bixler-demyer syndrome	Enrichment	FGFR1	1.79
333	Alk-positive large b-cell lymphoma	Enrichment	ALK	1.79
334	Pseudoxanthomatous diffuse cutaneous mastocytosis	Enrichment	KIT	1.79
335	Telangiectasia macularis eruptiva perstans	Enrichment	KIT	1.79
336	Acute mast cell leukemia	Enrichment	KIT	1.79
337	Egf-related primary hypomagnesemia with intellectual disability	Enrichment	EGF	1.79
338	Non-syndromic unicoronal craniosynostosis	Enrichment	FGFR2	1.79
339	Familial progressive hyper- and hypopigmentation	Enrichment	KITLG	1.79
340	Plaque-form urticaria pigmentosa	Enrichment	KIT	1.79
341	Interstitial lung disease specific to childhood	Enrichment	FGF10	1.79
342	Serous carcinoma of the corpus uteri	Enrichment	ERBB2	1.79
343	Ephb4-related lymphatic-related hydrops fetalis	Enrichment	EPHB4	1.79
344	Neurocutaneous melanocytosis	Enrichment	NRAS	1.79
345	Bullous diffuse cutaneous mastocytosis	Enrichment	KIT	1.79
346	Microcystic stromal tumor	Enrichment	CTNNB1	1.79
347	Vein of galen aneurysmal malformation	Enrichment	EPHB4	1.79
348	Testis seminoma	Enrichment	KIT	1.79
349	Brittle bone disorder	Enrichment	BMP1, EIF2B2, WNT1	1.75
350	Myasthenic syndrome, congenital, 4c, associated with acetylcholine receptor deficiency	Enrichment	CHRNE, MUSK	1.72
351	Achromatopsia	Enrichment	CNGA3, CNGB3	1.72
352	Periodic fever, familial, autosomal dominant	Enrichment	TNFRSF1A	1.70
353	Proteus syndrome	Enrichment	AKT1	1.70
354	Parkinson disease 1, autosomal dominant	Enrichment	SNCA	1.70
355	Coffin-lowry syndrome	Enrichment	RPS6KA3	1.70
356	Coloboma, ocular, with or without hearing impairment, cleft lip/palate, and/or impaired intellectual development	Enrichment	YAP1	1.70
357	Nail disorder, nonsyndromic congenital, 3	Enrichment	PLCD1	1.70
358	Complement hyperactivation, angiopathic thrombosis, and protein-losing enteropathy	Enrichment	CD55	1.70
359	Parkinson disease 4, autosomal dominant	Enrichment	SNCA	1.70
360	Blood group, cromer system	Enrichment	CD55	1.70
361	Macrothrombocytopenia, isolated, 1, autosomal dominant	Enrichment	TUBB1	1.70
362	Ataxia-oculomotor apraxia 3	Enrichment	PIK3R5	1.70
363	Autoimmune lymphoproliferative syndrome, type iii	Enrichment	PRKCD	1.70
364	Ciliary dyskinesia, primary, 47, and lissencephaly	Enrichment	TP73	1.70
365	Spondylometaphyseal dysplasia with corneal dystrophy	Enrichment	PLCB3	1.70
366	Short syndrome	Enrichment	PIK3R1	1.70
367	Immune dysregulation, autoimmunity, and autoinflammation	Enrichment	PLCG1	1.70
368	Parkinson-dementia syndrome	Enrichment	MAPT	1.70
369	Auriculocondylar syndrome 2a	Enrichment	PLCB4	1.70
370	Intellectual developmental disorder, x-linked 19	Enrichment	RPS6KA3	1.70
371	Supranuclear palsy, progressive, 1	Enrichment	MAPT	1.70
372	Uveal coloboma-cleft lip and palate-intellectual disability	Enrichment	YAP1	1.70
373	Progressive supranuclear palsy	Enrichment	MAPT	1.70
374	Spinocerebellar ataxia 14	Enrichment	PRKCG	1.70
375	Immunodeficiency 36 with lymphoproliferation	Enrichment	PIK3R1	1.70
376	Multiple sclerosis 5	Enrichment	TNFRSF1A	1.70
377	Autoinflammation, antibody deficiency, and immune dysregulation	Enrichment	PLCG2	1.70
378	Cowden syndrome 6	Enrichment	AKT1	1.70
379	Oocyte/zygote/embryo maturation arrest 23	Enrichment	TUBA4A	1.70
380	Frontotemporal dementia and/or amyotrophic lateral sclerosis 9	Enrichment	TUBA4A	1.70
381	Agammaglobulinemia 7, autosomal recessive	Enrichment	PIK3R1	1.70
382	Familial cold autoinflammatory syndrome 3	Enrichment	PLCG2	1.70
383	Congenital heart defects and ectodermal dysplasia	Enrichment	PRKD1	1.70
384	Developmental and epileptic encephalopathy 56	Enrichment	YWHAG	1.70
385	Tnf receptor-associated periodic fever syndrome	Enrichment	TNFRSF1A	1.70
386	Thrombocytopenia 6	Enrichment	SRC	1.70
387	Classic progressive supranuclear palsy syndrome	Enrichment	MAPT	1.70
388	Auriculocondylar syndrome 2b	Enrichment	PLCB4	1.70
389	Macrothrombocytopenia, isolated, 2, autosomal dominant	Enrichment	TUBA8	1.70
390	Congenital myopathy 26	Enrichment	TUBA4A	1.70
391	Spastic ataxia 11, autosomal dominant	Enrichment	TUBA4A	1.70
392	Atypical progressive supranuclear palsy syndrome	Enrichment	MAPT	1.70
393	Amyotrophic lateral sclerosis type 22	Enrichment	TUBA4A	1.70
394	Symptomatic form of coffin-lowry syndrome in female carriers	Enrichment	RPS6KA3	1.70
395	Polymicrogyria with optic nerve hypoplasia	Enrichment	TUBA8	1.70
396	Protein-losing enteropathy	Enrichment	CD55	1.70
397	Premature aging	Enrichment	VIM	1.70
398	Malignant epithelial tumor of salivary glands	Enrichment	PRKD1	1.70
399	Distal 17p13.3 microdeletion syndrome	Enrichment	YWHAE	1.70
400	Medulloblastoma	Enrichment	APC, CTNNB1	1.67
401	Hereditary breast carcinoma	Enrichment	AKT1, APC, CDH1, KRAS	1.66
402	Anhidrosis, isolated, with normal sweat glands	Enrichment	ITPR2	1.66
403	Acrodysostosis 1 with or without hormone resistance	Enrichment	PRKAR1A	1.66
404	Achromatopsia 2	Enrichment	CNGA3	1.66
405	Bladder dysfunction, autonomic, with impaired pupillary reflex and secondary cakut	Enrichment	CHRNA3	1.66
406	Baraitser-winter syndrome 1	Enrichment	ACTB	1.66
407	Charcot-marie-tooth disease, x-linked dominant, 6	Enrichment	PDK3	1.66
408	Caspase 8 deficiency	Enrichment	CASP8	1.66
409	Pseudohypoparathyroidism, type ic	Enrichment	GNAS	1.66
410	Lipodystrophy, congenital generalized, type 3	Enrichment	CAV1	1.66
411	Carney complex, type 1	Enrichment	PRKAR1A	1.66
412	Epilepsy, nocturnal frontal lobe, 4	Enrichment	CHRNA2	1.66
413	Congenital myopathy 2a, typical, autosomal dominant	Enrichment	ACTA1	1.66
414	Osseous heteroplasia, progressive	Enrichment	GNAS	1.66
415	Blood group, colton system	Enrichment	AQP1	1.66
416	Myasthenic syndrome, congenital, 2a, slow-channel	Enrichment	CHRNB1	1.66
417	Myasthenic syndrome, congenital, 2c, associated with acetylcholine receptor deficiency	Enrichment	CHRNB1	1.66
418	Charcot-marie-tooth disease, dominant intermediate b	Enrichment	DNM2	1.66
419	Dyskinesia with orofacial involvement, autosomal dominant	Enrichment	ADCY5	1.66
420	Myopathy, scapulohumeroperoneal	Enrichment	ACTA1	1.66
421	Myasthenic syndrome, congenital, 3a, slow-channel	Enrichment	CHRND	1.66
422	Aortic aneurysm, familial thoracic 8	Enrichment	PRKG1	1.66
423	Deafness, autosomal recessive 44	Enrichment	ADCY1	1.66
424	Pulmonary hypertension, primary, 3	Enrichment	CAV1	1.66
425	Ventricular tachycardia, familial	Enrichment	GNAI2	1.66
426	Acth-independent macronodular adrenal hyperplasia 1	Enrichment	GNAS	1.66
427	Megacystis-microcolon-intestinal hypoperistalsis syndrome 5	Enrichment	ACTG2	1.66
428	Neurodevelopmental disorder with hypotonia and dysmorphic facies	Enrichment	GNB2	1.66
429	Neurodevelopmental disorder with hyperkinetic movements and dyskinesia	Enrichment	ADCY5	1.66
430	Pituitary adenoma 3, multiple types	Enrichment	GNAS	1.66
431	Charcot-marie-tooth disease, demyelinating, type 1j	Enrichment	ITPR3	1.66
432	Congenital smooth muscle hamartoma, with or without hemihypertrophy	Enrichment	ACTB	1.66
433	Night blindness, congenital stationary, type1i	Enrichment	GUCY2D	1.66
434	Deafness, autosomal recessive 68	Enrichment	S1PR2	1.66
435	Cardioacrofacial dysplasia 2	Enrichment	PRKACB	1.66
436	Cardiomyopathy, familial hypertrophic, 6	Enrichment	PRKAG2	1.66
437	Neurodevelopmental disorder with hypotonia, impaired speech, and behavioral abnormalities	Enrichment	GNAI1	1.66
438	Myasthenic syndrome, congenital, 3c, associated with acetylcholine receptor deficiency	Enrichment	CHRND	1.66
439	Myxoma, intracardiac	Enrichment	PRKAR1A	1.66
440	Lipodystrophy, familial partial, type 7	Enrichment	CAV1	1.66
441	Glycogen storage disease of heart, lethal congenital	Enrichment	PRKAG2	1.66
442	Dyskinesia with orofacial involvement, autosomal recessive	Enrichment	ADCY5	1.66
443	Microvascular complications of diabetes 1	Enrichment	VEGFA	1.66
444	Epilepsy, nocturnal frontal lobe, 3	Enrichment	CHRNB2	1.66
445	Lodder-merla syndrome, type 2, with developmental delay and with or without cardiac arrhythmia	Enrichment	GNB5	1.66
446	Myasthenic syndrome, congenital, 3b, fast-channel	Enrichment	CHRND	1.66
447	Becker nevus syndrome	Enrichment	ACTB	1.66
448	Ovarian dysgenesis 8	Enrichment	ESR2	1.66
449	Dystonia-deafness syndrome 1	Enrichment	ACTB	1.66
450	Visceral neuropathy, familial, 3, autosomal dominant	Enrichment	ACTG2	1.66
451	Glycerol quantitative trait locus	Enrichment	AQP7	1.66
452	Lethal congenital contracture syndrome 5	Enrichment	DNM2	1.66
453	Congenital myopathy 2b, severe infantile, autosomal recessive	Enrichment	ACTA1	1.66
454	Moyamoya disease 6 with or without achalasia	Enrichment	GUCY1A1	1.66
455	Long qt syndrome 16	Enrichment	CALM3	1.66
456	Pigmented nodular adrenocortical disease, primary, 4	Enrichment	PRKACA	1.66
457	Charcot-marie-tooth disease, dominant intermediate f	Enrichment	GNB4	1.66
458	Autosomal dominant familial visceral neuropathy	Enrichment	ACTG2	1.66
459	Disorders of gnas inactivation	Enrichment	GNAS	1.66
460	Retinitis pigmentosa 45	Enrichment	CNGB1	1.66
461	Skeletal muscle glycogen content and metabolism quantitative trait locus	Enrichment	PRKAG3	1.66
462	Cardioacrofacial dysplasia 1	Enrichment	PRKACA	1.66
463	Intellectual developmental disorder, autosomal dominant 42	Enrichment	GNB1	1.66
464	Congenital myopathy 2c, severe infantile, autosomal dominant	Enrichment	ACTA1	1.66
465	Sick sinus syndrome 4	Enrichment	GNB2	1.66
466	Thrombocytopenia 8, with dysmorphic features and developmental delay	Enrichment	ACTB	1.66
467	Moyamoya disease with early-onset achalasia	Enrichment	GUCY1A1	1.66
468	Megalencephalic leukoencephalopathy with subcortical cysts 4, remitting	Enrichment	AQP4	1.66
469	Long qt syndrome 15	Enrichment	CALM2	1.66
470	Baraitser-winter syndrome	Enrichment	ACTB	1.66
471	Autosomal dominant charcot-marie-tooth disease type 2m	Enrichment	DNM2	1.66
472	Immunodeficiency 133 with ectodermal dysplasia with or without peripheral neuropathy	Enrichment	ITPR3	1.66
473	Prkar1b-related neurodegenerative dementia with intermediate filaments	Enrichment	PRKAR1B	1.66
474	Zebra body myopathy	Enrichment	ACTA1	1.66
475	Congenital smooth muscle hamartoma	Enrichment	ACTB	1.66
476	Developmental malformations-deafness-dystonia syndrome	Enrichment	ACTB	1.66
477	Monostotic fibrous dysplasia	Enrichment	GNAS	1.66
478	Actin-accumulation myopathy	Enrichment	ACTA1	1.66
479	Mazabraud syndrome	Enrichment	GNAS	1.66
480	Myopathic intestinal pseudoobstruction	Enrichment	ACTG2	1.66
481	Actg2 visceral myopathy	Enrichment	ACTG2	1.66
482	Meningioma	Enrichment	AKT1, PDGFB	1.64
483	Leukemia, acute lymphoblastic	Enrichment	FLT3, GNB1	1.64
484	Heritable pulmonary arterial hypertension	Enrichment	CAV1, GDF2	1.64
485	Body mass index quantitative trait locus 11	Enrichment	ADCY3, AQP7, BDNF, GNAS	1.63
486	Breast cancer	Enrichment	AKT1, CASP8, ESR1, GNG3, IL2	1.62
487	Ectodermal dysplasia, ectrodactyly, and macular dystrophy syndrome	Enrichment	CDH3	1.61
488	Elsahy-waters syndrome	Enrichment	CDH11	1.61
489	Spinocerebellar ataxia 12	Enrichment	PPP2R2B	1.61
490	Intellectual developmental disorder, autosomal dominant 3	Enrichment	CDH15	1.61
491	Mitral valve prolapse 2	Enrichment	DCHS1	1.61
492	Advanced sleep phase syndrome, familial, 2	Enrichment	CSNK1D	1.61
493	Neurodevelopmental disorder with involuntary movements	Enrichment	GNAO1	1.61
494	Ectodermal dysplasia 17 with or without limb malformations	Enrichment	LEF1	1.61
495	Teebi hypertelorism syndrome 2	Enrichment	CDH11	1.61
496	Mehmo syndrome	Enrichment	EIF2S3	1.61
497	Neurodevelopmental disorder with microcephaly, hypotonia, and absent language	Enrichment	PSMB1	1.61
498	Leukoencephalopathy with vanishing white matter 3	Enrichment	EIF2B3	1.61
499	Parkinson disease 25, autosomal recessive early-onset, with impaired intellectual development	Enrichment	PTPA	1.61
500	Houge-janssens syndrome 4	Enrichment	PPP2R5C	1.61
501	Agenesis of corpus callosum, cardiac, ocular, and genital syndrome	Enrichment	CDH2	1.61
502	Developmental and epileptic encephalopathy 17	Enrichment	GNAO1	1.61
503	Houge-janssens syndrome 2	Enrichment	PPP2R1A	1.61
504	Deafness, cataract, impaired intellectual development, and polyneuropathy	Enrichment	PSMC3	1.61
505	Hypotrichosis	Enrichment	CDH3	1.61
506	Arrhythmogenic right ventricular dysplasia, familial, 14	Enrichment	CDH2	1.61
507	Proteasome-associated autoinflammatory syndrome 6	Enrichment	PSMB9	1.61
508	Okur-chung neurodevelopmental syndrome	Enrichment	CSNK2A1	1.61
509	Menke-hennekam syndrome 1	Enrichment	CREBBP	1.61
510	Tsh producing pituitary tumor	Enrichment	CDH23	1.61
511	Attention deficit-hyperactivity disorder 8	Enrichment	CDH2	1.61
512	Rubinstein-taybi syndrome due to 16p13.3 microdeletion	Enrichment	CREBBP	1.61
513	Leukoencephalopathy with vanishing white matter 2	Enrichment	EIF2B2	1.61
514	Breast lobular carcinoma	Enrichment	CDH1	1.61
515	Menke-hennekam syndrome	Enrichment	CREBBP	1.61
516	Gnao1-related disorder	Enrichment	GNAO1	1.61
517	Ppp2r1a-related neurodevelopmental disorder	Enrichment	PPP2R1A	1.61
518	Wilms tumor 1	Enrichment	BRAF, IGF2	1.61
519	Osteogenesis imperfecta, type iii	Enrichment	BMP1, WNT1	1.61
520	Dandy-walker syndrome	Enrichment	BRAF, PDGFRB	1.51
521	Acromicric dysplasia	Enrichment	LTBP3	1.49
522	Cri-du-chat syndrome	Enrichment	SEMA5A	1.49
523	Blue rubber bleb nevus	Enrichment	TEK	1.49
524	Sorsby fundus dystrophy	Enrichment	TIMP3	1.49
525	Myeloproliferative disorder, chronic, with eosinophilia	Enrichment	PDGFRB	1.49
526	Fibromatosis, gingival, 1	Enrichment	SOS1	1.49
527	Tooth agenesis, selective, 4	Enrichment	WNT10A	1.49
528	Camurati-engelmann disease 1	Enrichment	TGFB1	1.49
529	Costello syndrome	Enrichment	HRAS	1.49
530	Insensitivity to pain, congenital, with anhidrosis	Enrichment	NTRK1	1.49
531	Trichomegaly	Enrichment	FGF5	1.49
532	Schopf-schulz-passarge syndrome	Enrichment	WNT10A	1.49
533	Visceral neuropathy, familial, 1, autosomal recessive	Enrichment	ERBB3	1.49
534	Kyphomelic dysplasia	Enrichment	CCN2	1.49
535	Omodysplasia 1	Enrichment	GPC6	1.49
536	Ulna and fibula, absence of, with severe limb deficiency	Enrichment	WNT7A	1.49
537	Bladder exstrophy and epispadias complex	Enrichment	WNT3	1.49
538	Osteopathia striata with cranial sclerosis	Enrichment	CTNNB1	1.49
539	Pulmonary hypoplasia, primary	Enrichment	FGF10	1.49
540	Dermatofibrosarcoma protuberans	Enrichment	PDGFB	1.49
541	Cervical cancer	Enrichment	FGFR3	1.49
542	Odontoonychodermal dysplasia	Enrichment	WNT10A	1.49
543	Tetraamelia syndrome 1	Enrichment	WNT3	1.49
544	Parkinson disease 8, autosomal dominant	Enrichment	GDF6	1.49
545	Piebald trait	Enrichment	KIT	1.49
546	Hyperinsulinemic hypoglycemia, familial, 4	Enrichment	INSR	1.49
547	Aural atresia, congenital	Enrichment	FGFR2	1.49
548	Keratosis, seborrheic	Enrichment	FGFR3	1.49
549	Multiple synostoses syndrome 2	Enrichment	GDF5	1.49
550	Osteogenesis imperfecta, type xv	Enrichment	WNT1	1.49
551	Myopathy, mitochondrial progressive, with congenital cataract and developmental delay	Enrichment	GFER	1.49
552	Cutis laxa, autosomal recessive, type ic	Enrichment	LTBP4	1.49
553	Silver-russell syndrome 3	Enrichment	IGF2	1.49
554	Robinow syndrome, autosomal dominant 3	Enrichment	FZD2	1.49
555	Osteogenesis imperfecta, type xiii	Enrichment	BMP1	1.49
556	Angioma, tufted	Enrichment	KDR	1.49
557	Fibular aplasia or hypoplasia, femoral bowing, and poly-, syn-, and oligodactyly	Enrichment	WNT7A	1.49
558	Brachydactyly, type a1, c	Enrichment	GDF5	1.49
559	Symphalangism, proximal, 1b	Enrichment	GDF5	1.49
560	Pain sensitivity quantitative trait locus 1	Enrichment	NTRK1	1.49
561	Antley-bixler syndrome without genital anomalies or disordered steroidogenesis	Enrichment	FGFR2	1.49
562	Spondyloepimetaphyseal dysplasia, li-shao-li type	Enrichment	CCN2	1.49
563	Waardenburg syndrome, type 2f	Enrichment	KITLG	1.49
564	Lymphatic malformation 11	Enrichment	TIE1	1.49
565	Noonan syndrome 12	Enrichment	RRAS2	1.49
566	Inflammatory bowel disease, immunodeficiency, and encephalopathy	Enrichment	TGFB1	1.49
567	Kowarski syndrome	Enrichment	GH1	1.49
568	Infantile myofibromatosis	Enrichment	PDGFRB	1.49
569	Rosette-forming glioneuronal tumor	Enrichment	FGFR1	1.49
570	Papillary renal cell carcinoma	Enrichment	MET	1.49
571	Congenital mesoblastic nephroma	Enrichment	NTRK3	1.49
572	Camurati-engelmann disease	Enrichment	TGFB1	1.49
573	Microphthalmia/coloboma 6	Enrichment	GDF6	1.49
574	Periampullary adenoma	Enrichment	APC	1.49
575	Gastric adenocarcinoma and proximal polyposis of the stomach	Enrichment	APC	1.49
576	Cervix carcinoma	Enrichment	FGFR3	1.49
577	Fibrosarcoma	Enrichment	NTRK3	1.49
578	Retinitis pigmentosa 38	Enrichment	MERTK	1.49
579	Proximal symphalangism	Enrichment	GDF5	1.49
580	Craniosynostosis 7	Enrichment	BMP2	1.49
581	Acute myeloid leukemia without maturation	Enrichment	FLT3	1.49
582	Congenital amegakaryocytic thrombocytopenia	Enrichment	THPO	1.49
583	Interfrontal craniofaciosynostosis	Enrichment	FGFR1	1.49
584	Juvenile nasopharyngeal angiofibroma	Enrichment	CTNNB1	1.49
585	Short stature due to growth hormone qualitative anomaly	Enrichment	GH1	1.49
586	Autosomal dominant nonsyndromic deafness	Enrichment	FGFR2	1.49
587	Chronic eosinophilic leukemia	Enrichment	PDGFRA	1.49
588	Growth delay due to insulin-like growth factor type 1 deficiency	Enrichment	IGF1	1.49
589	Teratoma	Enrichment	CTNNB1	1.49
590	B-lymphoblastic leukemia/lymphoma with recurrent genetic abnormality	Enrichment	PDGFRA	1.49
591	Bladder exstrophy-epispadias-cloacal exstrophy complex	Enrichment	WNT3	1.49
592	Mixed phenotype acute leukemia with t(9;22)(q34.1;q11.2)	Enrichment	FLT3	1.49
593	B-lymphoblastic leukemia/lymphoma with t	Enrichment	KIT	1.49
594	Silver-russell syndrome due to an imprinting defect of 11p15	Enrichment	IGF2	1.49
595	Tafro syndrome	Enrichment	MAP2K2	1.49
596	Wooly hair nevus	Enrichment	HRAS	1.49
597	Silver-russell syndrome due to 11p15 microduplication	Enrichment	IGF2	1.49
598	Cone-rod dystrophy 6	Enrichment	CNGB3, GUCY2D	1.44
599	Congenital myasthenic syndrome	Enrichment	CHRNA1, CHRNE	1.44
600	Cakut	Enrichment	ACTG1, GDF6, LIFR	1.43
601	Pulmonary hypertension, primary, 1	Enrichment	EIF2AK4, GDF2	1.41
602	Scoliosis, isolated 1	Enrichment	MAPK7	1.41
603	Microcephaly and chorioretinopathy, autosomal recessive, 1	Enrichment	TUBGCP6	1.41
604	Ovarian germ cell cancer	Enrichment	CBL	1.41
605	Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy 2	Enrichment	PIK3R5	1.41
606	Pick disease of brain	Enrichment	MAPT	1.41
607	Spermatogenic failure 17	Enrichment	PLCZ1	1.41
608	Cortical dysplasia, complex, with other brain malformations 4	Enrichment	TUBG1	1.41
609	Cortical dysplasia, complex, with other brain malformations 15	Enrichment	TUBGCP2	1.41
610	Parkinson disease 15, autosomal recessive early-onset	Enrichment	SNCA	1.41
611	Immunodeficiency 127	Enrichment	TNF	1.41
612	Microcephaly and chorioretinopathy 1	Enrichment	TUBGCP6	1.41
613	Cataract 30	Enrichment	VIM	1.41
614	Ocular melanoma	Enrichment	PLCB4	1.41
615	Intermittent hydrarthrosis	Enrichment	TNFRSF1A	1.41
616	Malignant germ cell tumor of ovary	Enrichment	CBL	1.41
617	Primary ovarian insufficiency	Enrichment	BMP6, KDR, NOS3, NTRK1	1.40
618	Spinocerebellar ataxia 29	Enrichment	ITPR1	1.36
619	Pseudohypoparathyroidism, type ia	Enrichment	GNAS	1.36
620	Amelogenesis imperfecta, type ig	Enrichment	PRKAR1A	1.36
621	Pituitary adenoma 4, acth-secreting	Enrichment	GNAI2	1.36
622	Palmoplantar keratoderma, bothnian type	Enrichment	AQP5	1.36
623	Aortic aneurysm, familial thoracic 2	Enrichment	ACTA2	1.36
624	Pseudopseudohypoparathyroidism	Enrichment	GNAS	1.36
625	Ventricular tachycardia, catecholaminergic polymorphic, 4	Enrichment	CALM1	1.36
626	Deafness, autosomal dominant 20	Enrichment	ACTG1	1.36
627	Smooth muscle dysfunction syndrome	Enrichment	ACTA2	1.36
628	Aortic aneurysm, familial thoracic 6	Enrichment	ACTA2	1.36
629	Diabetes insipidus, nephrogenic, 2, autosomal	Enrichment	AQP2	1.36
630	Baraitser-winter syndrome 2	Enrichment	ACTG1	1.36
631	Lethal congenital contracture syndrome 8	Enrichment	ADCY6	1.36
632	Duodenal atresia	Enrichment	GUCY2C	1.36
633	Bleeding disorder, platelet-type, 19	Enrichment	PRKACG	1.36
634	Epiphyseal chondrodysplasia, miura type	Enrichment	NPR2	1.36
635	Moyamoya disease 5	Enrichment	ACTA2	1.36
636	Night blindness, congenital stationary, type 1h	Enrichment	GNB3	1.36
637	Long qt syndrome 14	Enrichment	CALM1	1.36
638	Marbach-schaaf neurodevelopmental syndrome	Enrichment	PRKAR1B	1.36
639	Spinocerebellar ataxia 48	Enrichment	STUB1	1.36
640	Usher syndrome, type iv	Enrichment	PRKAR1A	1.36
641	Retinitis pigmentosa 49	Enrichment	CNGA1	1.36
642	Acrodysostosis	Enrichment	PRKAR1A	1.36
643	Pseudohypoparathyroidism	Enrichment	GNAS	1.36
644	Chromosome 15q13.3 deletion syndrome	Enrichment	CHRNA7	1.36
645	Acromesomelic dysplasia 1	Enrichment	NPR2	1.36
646	Body mass index quantitative trait locus 19	Enrichment	ADCY3	1.36
647	Fibrolamellar carcinoma	Enrichment	PRKACA	1.36
648	Diarrhea 6	Enrichment	GUCY2C	1.36
649	Ciliary dyskinesia, primary, 18	Enrichment	PRKAR1B	1.36
650	Hypopituitarism	Enrichment	GNAI2	1.36
651	Lodder-merla syndrome, type 1, with impaired intellectual development and cardiac arrhythmia	Enrichment	GNB5	1.36
652	Congenital diarrhea 6	Enrichment	GUCY2C	1.36
653	Intestinal obstruction in the newborn due to guanylate cyclase 2c deficiency	Enrichment	GUCY2C	1.36
654	Isolated primary pigmented nodular adrenocortical disease	Enrichment	PRKAR1A	1.36
655	Acth-independent macronodular adrenal hyperplasia	Enrichment	GNAS	1.36
656	Intestinal obstruction	Enrichment	ACTG2	1.36
657	Cerebral visual impairment	Enrichment	GNB1	1.36
658	Alzheimer disease, familial, 1	Enrichment	CSF1R, MAPT	1.36
659	Inherited isolated arrhythmogenic cardiomyopathy, dominant-right variant	Enrichment	CDH2, TGFB3	1.35
660	Rare autosomal recessive non-syndromic sensorineural deafness type dfnb	Enrichment	ADCY1, HGF, MET, ROR1, S1PR2	1.35
661	Ectrodactyly and ectodermal dysplasia without cleft lip/palate	Enrichment	LEF1	1.32
662	Blepharocheilodontic syndrome 1	Enrichment	CDH1	1.32
663	Mitral valve prolapse 1	Enrichment	DCHS1	1.32
664	Epiphyseal dysplasia, multiple, with early-onset diabetes mellitus	Enrichment	EIF2AK3	1.32
665	Thumb deformity	Enrichment	CREBBP	1.32
666	Pulmonary venoocclusive disease 1, autosomal dominant	Enrichment	EIF2AK4	1.32
667	Van maldergem syndrome 1	Enrichment	DCHS1	1.32
668	Hypotrichosis, congenital, with juvenile macular dystrophy	Enrichment	CDH3	1.32
669	Premature ovarian failure 3	Enrichment	AGO2	1.32
670	Pulmonary venoocclusive disease 2, autosomal recessive	Enrichment	EIF2AK4	1.32
671	Deafness, autosomal recessive 84a	Enrichment	CDH23	1.32
672	Proteasome-associated autoinflammatory syndrome 5	Enrichment	PSMB10	1.32
673	Immunodeficiency 121 with autoinflammation	Enrichment	PSMB10	1.32
674	Birk-aharoni syndrome	Enrichment	PSMC1	1.32
675	Hypotonia, ataxia, developmental delay, and tooth enamel defect syndrome	Enrichment	CTBP1	1.32
676	Neurodevelopmental disorder with language delay and behavioral abnormalities, with or without seizures	Enrichment	AGO1	1.32
677	Leukoencephalopathy with vanishing white matter 4	Enrichment	EIF2B4	1.32
678	Pulmonary venoocclusive disease 1	Enrichment	EIF2AK4	1.32
679	Pulmonary venoocclusive disease 2	Enrichment	EIF2AK4	1.32
680	Combined saposin deficiency	Enrichment	CDH23	1.32
681	Acute myeloid leukemia with kat6a-crebbp fusion	Enrichment	CREBBP	1.32
682	Combined psap deficiency	Enrichment	CDH23	1.32
683	Houge-janssens syndrome 3	Enrichment	PPP2CA	1.32
684	Pulmonary venoocclusive disease	Enrichment	EIF2AK4	1.32
685	Familial isolated pituitary adenoma	Enrichment	CDH23	1.32
686	Brachydactyly, type a1	Enrichment	GDF5	1.32
687	Achondroplasia	Enrichment	FGFR3	1.32
688	Brachydactyly, type c	Enrichment	GDF5	1.32
689	Hypogonadotropic hypogonadism 2 with or without anosmia	Enrichment	FGFR1	1.32
690	Larsen syndrome	Enrichment	FGFR3	1.32
691	Klippel-feil syndrome 1, autosomal dominant	Enrichment	GDF6	1.32
692	Ataxia-telangiectasia	Enrichment	BRAF	1.32
693	Exfoliation syndrome	Enrichment	LTBP2	1.32
694	Tumoral calcinosis, hyperphosphatemic, familial, 1	Enrichment	FGF23	1.32
695	Acromesomelic dysplasia 2a	Enrichment	GDF5	1.32
696	Thrombocythemia 1	Enrichment	THPO	1.32
697	Hypophosphatemic rickets, autosomal dominant	Enrichment	FGF23	1.32
698	Acromesomelic dysplasia 2c	Enrichment	GDF5	1.32
699	Acromesomelic dysplasia 2b	Enrichment	GDF5	1.32
700	Leukoencephalopathy, hereditary diffuse, with spheroids 1	Enrichment	CSF1R	1.32
701	Mullerian duct aplasia, unilateral renal agenesis, and cervicothoracic somite anomalies	Enrichment	WNT4	1.32
702	Microphthalmia, syndromic 9	Enrichment	WNT7B	1.32
703	Tooth agenesis, selective, 2	Enrichment	WNT10A	1.32
704	Stuve-wiedemann syndrome 1	Enrichment	LIFR	1.32
705	Autoimmune disease 1	Enrichment	FOXD3	1.32
706	Nuchal bleb, familial	Enrichment	SOS1	1.32
707	Muscular dystrophy, duchenne type	Enrichment	LTBP4	1.32
708	Transposition of the great arteries, dextro-looped	Enrichment	BMP2	1.32
709	Neurodevelopmental disorder with spastic diplegia and visual defects	Enrichment	CTNNB1	1.32
710	Chromosome 8p11 myeloproliferative syndrome	Enrichment	FGFR1	1.32
711	Cenani-lenz syndactyly syndrome	Enrichment	APC	1.32
712	Dyskeratosis congenita, autosomal dominant 6	Enrichment	THPO	1.32
713	Neonatal nephrocutaneous inflammatory syndrome	Enrichment	EGFR	1.32
714	Anus, imperforate	Enrichment	CTNNB1	1.32
715	Exudative vitreoretinopathy 7	Enrichment	CTNNB1	1.32
716	Weill-marchesani syndrome 1	Enrichment	LTBP2	1.32
717	Primary polycythemia	Enrichment	EPOR	1.32
718	Tethered spinal cord syndrome	Enrichment	BRAF	1.32
719	Bronchopulmonary dysplasia	Enrichment	MUSK	1.32
720	Autosomal recessive cutis laxa type i	Enrichment	LTBP1	1.32
721	Isolated growth hormone deficiency, type ib	Enrichment	GH1	1.32
722	Nail disease	Enrichment	FZD6	1.32
723	Lymphatic malformation 7	Enrichment	EPHB4	1.32
724	Capillary malformation-arteriovenous malformation 2	Enrichment	EPHB4	1.32
725	Tetraamelia syndrome	Enrichment	WNT3	1.32
726	Growth delay due to insulin-like growth factor i resistance	Enrichment	IGF1R	1.32
727	High bone mass osteogenesis imperfecta	Enrichment	BMP1	1.32
728	Colon adenocarcinoma	Enrichment	APC	1.32
729	Neonatal inflammatory skin and bowel disease	Enrichment	EGFR	1.32
730	Mixed phenotype acute leukemia with t	Enrichment	FLT3	1.32
731	Geleophysic dysplasia	Enrichment	LTBP3	1.32
732	Renal cell carcinoma	Enrichment	MET	1.32
733	Stüve-wiedemann syndrome	Enrichment	LIFR	1.32
734	Testicular cancer	Enrichment	FGFR3	1.32
735	Isolated klippel-feil syndrome	Enrichment	GDF6	1.32
736	Beckwith-wiedemann syndrome due to imprinting defect of 11p15	Enrichment	IGF2	1.32
737	Apc-associated polyposis conditions	Enrichment	APC	1.32
738	Microphthalmia	Enrichment	SOX2, WNT7B	1.30
739	Corpus callosum, agenesis of	Enrichment	CDH2, CREBBP	1.30
740	Isolated corpus callosum agenesis	Enrichment	CDH2, CREBBP	1.30
741	Rare genetic intellectual disability	Enrichment	CREBBP, GNAO1	1.30
742	Intellectual disability-hypoplastic corpus callosum-preauricular tag syndrome	Enrichment	CDH2, CREBBP	1.30
743	Hypertension, essential	Enrichment	GNB3, NOS3	1.28
744	West syndrome	Enrichment	NTRK2, PLCB1, TSC2	1.25
745	Macrothrombocytopenia and granulocyte inclusions with or without nephritis or sensorineural hearing loss	Enrichment	TUBB1	1.23
746	Polycystic kidney disease, infantile severe, with tuberous sclerosis	Enrichment	TSC2	1.23
747	Psoriatic arthritis	Enrichment	TNF	1.23
748	Congenital lipomatous overgrowth, vascular malformations, and epidermal nevi	Enrichment	PIK3R1	1.23
749	Nephrotic syndrome, type 3	Enrichment	PLCE1	1.23
750	Tuberous sclerosis 2	Enrichment	TSC2	1.23
751	Immunodeficiency 14a with lymphoproliferation, autosomal dominant	Enrichment	PIK3R1	1.23
752	Miller-dieker lissencephaly syndrome	Enrichment	YWHAE	1.23
753	Chromosome 17p13.3, centromeric, duplication syndrome	Enrichment	YWHAE	1.23
754	Cortical dysplasia, complex, with other brain malformations 5	Enrichment	TUBB2A	1.23
755	Xanthinuria, type ii	Enrichment	TSC2	1.23
756	Immunodeficiency 14	Enrichment	PIK3R1	1.23
757	Migraine without aura	Enrichment	TNF	1.23
758	Periventricular leukomalacia	Enrichment	RPS6KC1	1.23
759	Respiratory failure	Enrichment	TP73	1.23
760	Cone-rod dystrophy 2	Enrichment	CNGA1, CNGA3, CNGB3, GUCY2D	1.21
761	Congenital myopathy	Enrichment	ACTA1, CHRNA1	1.20
762	Kaposi sarcoma	Enrichment	IL6	1.19
763	Isolated growth hormone deficiency, type ii	Enrichment	GH1	1.19
764	Erythrocytosis, familial, 1	Enrichment	EPOR	1.19
765	Ectodermal dysplasia 10b, hypohidrotic/hair/tooth type, autosomal recessive	Enrichment	WNT10A	1.19
766	Microphthalmia, syndromic 3	Enrichment	SOX2	1.19
767	Thyroid cancer, nonmedullary, 1	Enrichment	BRAF	1.19
768	Microtia-anotia	Enrichment	BMP5	1.19
769	Neurofibromatosis-noonan syndrome	Enrichment	MAP2K2	1.19
770	Chromosome 22q11.2 deletion syndrome, distal	Enrichment	MAPK1	1.19
771	Pilomatrixoma	Enrichment	CTNNB1	1.19
772	Cholangiocarcinoma	Enrichment	ROS1	1.19
773	Barrett esophagus	Enrichment	ERBB2	1.19
774	Alazami syndrome	Enrichment	CTNNB1	1.19
775	Lung sarcomatoid carcinoma	Enrichment	KRAS	1.19
776	Weill-marchesani syndrome	Enrichment	LTBP2	1.19
777	Chronic myelomonocytic leukemia	Enrichment	FLT3	1.19
778	Ectodermal dysplasia	Enrichment	WNT10A	1.19
779	Retinopathy of prematurity	Enrichment	FZD4	1.19
780	Pilocytic astrocytoma	Enrichment	KRAS	1.19
781	Newborn respiratory distress syndrome	Enrichment	BRAF	1.19
782	Epidermolytic nevus	Enrichment	HRAS	1.19
783	Eyelid coloboma	Enrichment	FZD5	1.19
784	Silver-russell syndrome due to a point mutation	Enrichment	IGF2	1.19
785	Non-syndromic bicoronal craniosynostosis	Enrichment	FGFR3	1.19
786	Systemic mastocytosis with associated hematologic neoplasm	Enrichment	KIT	1.19
787	Systemic-onset juvenile idiopathic arthritis	Enrichment	IL6	1.19
788	Gingival fibromatosis	Enrichment	SOS1	1.19
789	Male infertility due to gonadal dysgenesis or sperm disorder	Enrichment	SOS2	1.19
790	Lens coloboma	Enrichment	FZD5	1.19
791	Mccune-albright syndrome	Enrichment	GNAS	1.19
792	Gillespie syndrome	Enrichment	ITPR1	1.19
793	Diarrhea 3, secretory sodium, congenital, with or without other congenital anomalies	Enrichment	GUCY2C	1.19
794	Myopathy, centronuclear, x-linked	Enrichment	DNM2	1.19
795	Multiple pterygium syndrome, escobar variant	Enrichment	CHRNG	1.19
796	Estrogen resistance	Enrichment	ESR1	1.19
797	Epilepsy, familial focal, with variable foci 2	Enrichment	NPR2	1.19
798	Nephrogenic diabetes insipidus	Enrichment	AQP2	1.19
799	Polr3-related leukodystrophy	Enrichment	GUCY2D	1.19
800	Cushing syndrome due to bilateral macronodular adrenocortical disease	Enrichment	GNAS	1.19
801	Hypomyelination neuropathy-arthrogryposis syndrome	Enrichment	ADCY6	1.19
802	Thrombocytopenia	Enrichment	SRC, THPO, TUBB1	1.16
803	Optic atrophy plus syndrome	Enrichment	CNGA3, CNGB3, GUCY2D	1.15
804	Menkes disease	Enrichment	EIF2AK3	1.15
805	Intraocular pressure quantitative trait locus	Enrichment	CREBBP	1.15
806	Lessel-kreienkamp syndrome	Enrichment	AGO2	1.15
807	Advanced sleep phase syndrome	Enrichment	CSNK1D	1.15
808	Thyroid hemiagenesis	Enrichment	PSMD3	1.15
809	Small cell cancer of the lung	Enrichment	TP73	1.11
810	Auriculocondylar syndrome 1	Enrichment	PLCB4	1.11
811	Megalencephaly-capillary malformation-polymicrogyria syndrome	Enrichment	PIK3R2	1.11
812	Megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome 1	Enrichment	PIK3R2	1.11
813	Developmental and epileptic encephalopathy 12	Enrichment	PLCB1	1.11
814	Congenital generalized lipodystrophy	Enrichment	FOS	1.11
815	Malignant epithelioid hemangioendothelioma	Enrichment	YAP1	1.11
816	Hereditary ataxia	Enrichment	PRKCG	1.11
817	Tubulinopathy	Enrichment	TUBB2A	1.11
818	Autosomal recessive chorioretinopathy-microcephaly syndrome	Enrichment	TUBGCP6	1.11
819	Cerebral malaria	Enrichment	TNF	1.11
820	Cataract 6, multiple types	Enrichment	EPHA2	1.10
821	Arrhythmogenic right ventricular dysplasia, familial, 1	Enrichment	TGFB3	1.10
822	Norrie disease	Enrichment	FZD4	1.10
823	Rheumatoid arthritis, systemic juvenile	Enrichment	IL6	1.10
824	Atrioventricular septal defect	Enrichment	BMP5	1.10
825	Familial adenomatous polyposis 1	Enrichment	APC	1.10
826	Congenital heart defects, multiple types, 4	Enrichment	BMP7	1.10
827	Juvenile glaucoma	Enrichment	LTBP2	1.10
828	Arrhythmogenic right ventricular dysplasia 1	Enrichment	TGFB3	1.10
829	Persistent hyperplastic primary vitreous	Enrichment	FZD4	1.10
830	Autosomal recessive hypohidrotic ectodermal dysplasia syndrome	Enrichment	WNT10A	1.10
831	Aniridia	Enrichment	EPHA2	1.10
832	Coloboma of choroid and retina	Enrichment	FZD5	1.10
833	Familial cerebral saccular aneurysm	Enrichment	ANGPTL6	1.10
834	Parkinson disease, late-onset	Enrichment	MAPT, SNCA	1.09
835	Myocardial infarction	Enrichment	ESR1, GUCY1A1	1.08
836	Chorea, benign hereditary	Enrichment	ADCY5	1.07
837	Nemaline myopathy 2	Enrichment	ACTA1	1.07
838	Megacystis-microcolon-intestinal hypoperistalsis syndrome 1	Enrichment	ACTG2	1.07
839	Spastic paraplegia 17, autosomal dominant	Enrichment	GNG3	1.07
840	Pseudohypoparathyroidism, type ib	Enrichment	GNAS	1.07
841	Autoimmune lymphoproliferative syndrome	Enrichment	ACTA2	1.07
842	Lipodystrophy, congenital generalized, type 2	Enrichment	GNG3	1.07
843	Carney complex variant	Enrichment	PRKAR1A	1.07
844	Spinocerebellar ataxia 15	Enrichment	ITPR1	1.07
845	Arrhythmogenic right ventricular dysplasia, familial, 10	Enrichment	PRKAR1A	1.07
846	Aminoacylase 1 deficiency	Enrichment	ACTB	1.07
847	Meconium ileus	Enrichment	GUCY2C	1.07
848	Short stature with nonspecific skeletal abnormalities 1	Enrichment	NPR2	1.07
849	Achromatopsia 4	Enrichment	GNAI3	1.07
850	Tobacco addiction	Enrichment	CHRNA4	1.07
851	Contractures, pterygia, and spondylocarpotarsal fusion syndrome 1b	Enrichment	CHRNG	1.07
852	Arthrogryposis multiplex congenita 3, myogenic type	Enrichment	ESR1	1.07
853	Color blindness	Enrichment	CNGA3	1.07
854	Diabetes insipidus	Enrichment	AQP2	1.07
855	Intermediate nemaline myopathy	Enrichment	ACTA1	1.07
856	Familial sick sinus syndrome	Enrichment	GNB2	1.07
857	Pseudomyogenic hemangioendothelioma	Enrichment	ACTB	1.07
858	Endometrial cancer	Enrichment	CDH1, FGFR2	1.04
859	Pituitary adenoma 5, multiple types	Enrichment	CDH23	1.03
860	Prolactinoma	Enrichment	CDH23	1.03
861	Vacterl association	Enrichment	CDH13	1.03
862	Glaucoma, primary open angle	Enrichment	LTBP2	1.03
863	Coloboma of optic nerve	Enrichment	FZD5	1.03
864	Cowden syndrome 1	Enrichment	EGFR	1.03
865	Weyers acrofacial dysostosis	Enrichment	CTNNB1	1.03
866	Hemihyperplasia, isolated	Enrichment	IGF2	1.03
867	Wilms tumor, aniridia, genitourinary anomalies, and impaired intellectual development syndrome	Enrichment	BDNF	1.03
868	Type 1 diabetes mellitus	Enrichment	IL6	1.03
869	Wilms tumor 5	Enrichment	BRAF	1.03
870	Dental anomalies and short stature	Enrichment	LTBP3	1.03
871	Anterior segment dysgenesis 5	Enrichment	BMP4	1.03
872	Renal dysplasia, cystic	Enrichment	WNT9B	1.03
873	Mitochondrial dna depletion syndrome 1	Enrichment	TYMP	1.03
874	Inflammatory bowel disease 25, autosomal recessive	Enrichment	TGFB1	1.03
875	Inflammatory myofibroblastic tumor	Enrichment	ALK	1.03
876	Renal hypoplasia	Enrichment	WNT9B	1.03
877	Diarrhea	Enrichment	WNT2B	1.03
878	Adrenocortical carcinoma	Enrichment	CTNNB1	1.03
879	Il10-related early-onset inflammatory bowel disease	Enrichment	TGFB1	1.03
880	Multicystic kidney dysplasia	Enrichment	FZD3	1.03
881	Multicystic dysplastic kidney	Enrichment	FZD3	1.03
882	Dementia, lewy body	Enrichment	SNCA	1.02
883	Chromosome 15q11.2 deletion syndrome	Enrichment	TUBG1	1.02
884	Myeloproliferative neoplasm	Enrichment	CBL	1.02
885	Vascular dementia	Enrichment	TNF	1.02
886	Dementia	Enrichment	MAPT	1.02
887	Aggressive systemic mastocytosis	Enrichment	CBL	1.02
888	Endometrial stromal sarcoma	Enrichment	YWHAE	1.02
889	Cone dystrophy	Enrichment	CNGA3, GUCY2D	1.02
890	Undetermined early-onset epileptic encephalopathy	Enrichment	FGF12, NTRK2, YWHAG	1.00
891	Alzheimer disease 2	Enrichment	NOS3	0.98
892	Visceral myopathy 1	Enrichment	ACTG2	0.98
893	Choroidal dystrophy, central areolar, 1	Enrichment	GUCY2D	0.98
894	3-methylglutaconic aciduria, type iii	Enrichment	GUCY2D	0.98
895	Congenital myopathy 3 with rigid spine	Enrichment	ACTA1	0.98
896	Myasthenic syndrome, congenital, 4a, slow-channel	Enrichment	CHRNE	0.98
897	Myasthenic syndrome, congenital, 4b, fast-channel	Enrichment	CHRNE	0.98
898	Macular degeneration	Enrichment	CNGA3	0.98
899	Severe congenital nemaline myopathy	Enrichment	ACTA1	0.98
900	Silver-russell syndrome 1	Enrichment	IGF2	0.96
901	Squamous cell carcinoma, head and neck	Enrichment	EGFR	0.96
902	Coats disease	Enrichment	FZD4	0.96
903	Waardenburg syndrome, type 2e	Enrichment	KITLG	0.96
904	Renal cell carcinoma, papillary, 1	Enrichment	MET	0.96
905	Essential thrombocythemia	Enrichment	THPO	0.96
906	Hereditary hemorrhagic telangiectasia	Enrichment	GDF2	0.96
907	Hypophosphatemic rickets	Enrichment	FGF23	0.96
908	B-lymphoblastic leukemia/lymphoma with t(9;22)(q34.1;q11.2)	Enrichment	FLT3	0.96
909	Melanoma, uveal	Enrichment	PLCB4	0.95
910	Keratoconus	Enrichment	TSC1	0.95
911	Kidney clear cell sarcoma	Enrichment	YWHAE	0.95
912	Vater/vacterl association	Enrichment	CDH13	0.94
913	Congenital nervous system abnormality	Enrichment	CREBBP, CTNNB1, EIF2B2, FGFR3, GNAO1	0.93
914	Nervous system disease	Enrichment	CREBBP, CTNNB1, EIF2B2, FGFR3, GNAO1	0.93
915	Developmental and epileptic encephalopathy 1	Enrichment	CSNK1E, GNAO1	0.91
916	Arthrogryposis, distal, type 1a	Enrichment	MET	0.91
917	Glioma susceptibility 1	Enrichment	ERBB2	0.91
918	Renal hypodysplasia/aplasia 1	Enrichment	WNT9B	0.91
919	Isolated growth hormone deficiency, type ia	Enrichment	GH1	0.91
920	Lymphoma, non-hodgkin, familial	Enrichment	BRAF	0.91
921	Mitochondrial dna depletion syndrome 4b	Enrichment	TYMP	0.91
922	Neuroblastoma	Enrichment	ALK	0.91
923	Early-onset posterior polar cataract	Enrichment	EPHA2	0.91
924	Myopathy, centronuclear, 1	Enrichment	DNM2	0.91
925	Ventricular tachycardia, catecholaminergic polymorphic, 1, with or without atrial dysfunction and/or dilated cardiomyopathy	Enrichment	CALM1	0.91
926	Intestinal pseudo-obstruction	Enrichment	ACTG2	0.91
927	Typical nemaline myopathy	Enrichment	ACTA1	0.91
928	Polycystic kidney disease 1 with or without polycystic liver disease	Enrichment	TSC2	0.88
929	Myelofibrosis	Enrichment	SRC	0.88
930	Semantic dementia	Enrichment	MAPT	0.88
931	Polycystic kidney disease 1	Enrichment	TSC2	0.88
932	Overgrowth syndrome	Enrichment	PIK3R1	0.88
933	Developmental dysplasia of the hip 1	Enrichment	PSMC3	0.86
934	Wolf-hirschhorn syndrome	Enrichment	CTBP1	0.86
935	Rubinstein-taybi syndrome 1	Enrichment	CREBBP	0.86
936	Usher syndrome, type id	Enrichment	CDH23	0.86
937	Deafness, autosomal recessive 12	Enrichment	CDH23	0.86
938	Chromosome 16p13.3 deletion syndrome, proximal	Enrichment	CREBBP	0.86
939	Patent ductus arteriosus	Enrichment	PSMC3	0.86
940	Hypertrichosis	Enrichment	CREBBP	0.86
941	Syndromic rod-cone dystrophy	Enrichment	CDH23	0.86
942	Cleft lip with or without cleft palate	Enrichment	CDH1	0.86
943	Orofacial cleft 1	Enrichment	FGF10	0.86
944	Cardiomyopathy, familial hypertrophic, 4	Enrichment	BRAF	0.86
945	Atypical chronic myeloid leukemia, bcr-abl1 negative	Enrichment	FLT3	0.86
946	Hypogonadotropic hypogonadism	Enrichment	FGFR1	0.86
947	Congenital central hypoventilation syndrome	Enrichment	BDNF	0.86
948	Primary hyperaldosteronism	Enrichment	BRAF	0.86
949	Colonic benign neoplasm	Enrichment	APC	0.86
950	Mitochondrial neurogastrointestinal encephalomyopathy	Enrichment	TYMP	0.86
951	Brachydactyly	Enrichment	GNAS	0.84
952	Childhood-onset nemaline myopathy	Enrichment	ACTA1	0.84
953	Long qt syndrome	Enrichment	CALM1, CALM2	0.83
954	Gastroesophageal reflux	Enrichment	RPS6KA3	0.83
955	Orthostatic intolerance	Enrichment	RPS6KA3	0.83
956	Lennox-gastaut syndrome	Enrichment	MAPK10	0.83
957	Type 2 diabetes mellitus	Enrichment	IL6, INSR	0.82
958	Cat eye syndrome	Enrichment	FZD5	0.82
959	Meier-gorlin syndrome 1	Enrichment	FGFR2	0.82
960	Peters-plus syndrome	Enrichment	BMP4	0.82
961	Stickler syndrome	Enrichment	BMP4	0.82
962	Melanoma	Enrichment	BRAF	0.82
963	Primary bone dysplasia	Enrichment	FGFR3	0.82
964	Connective tissue disease	Enrichment	ACTA2, FGFR3	0.81
965	Peripheral nervous system disease	Enrichment	CHRNG, NGF	0.81
966	Neuropathy	Enrichment	CHRNG, NGF	0.81
967	Prostate cancer	Enrichment	CDH1, EPHB2	0.81
968	Meniere disease	Enrichment	CDH23	0.80
969	Usher syndrome, type iia	Enrichment	CDH23	0.80
970	Spastic paraplegia 4, autosomal dominant	Enrichment	GNAS	0.79
971	Leber congenital amaurosis 1	Enrichment	GUCY2D	0.79
972	Catecholaminergic polymorphic ventricular tachycardia 1	Enrichment	CALM1	0.79
973	Hypothyroidism	Enrichment	GNB1	0.79
974	Nephrotic syndrome, type 1	Enrichment	PLCE1	0.78
975	Charge syndrome	Enrichment	TNFRSF1A	0.78
976	Developmental and epileptic encephalopathy 14	Enrichment	PLCB1	0.78
977	Progressive non-fluent aphasia	Enrichment	MAPT	0.78
978	Cowden syndrome	Enrichment	AKT1	0.78
979	Behavioral variant of frontotemporal dementia	Enrichment	MAPT	0.78
980	Meningioma, familial	Enrichment	PDGFB	0.78
981	Nanophthalmos	Enrichment	SOX2	0.78
982	Osteochondrodysplasia	Enrichment	FGFR3	0.78
983	Eye disease	Enrichment	CNGA3, CNGB3	0.75
984	Choreatic disease	Enrichment	GNAO1	0.75
985	Cutis laxa	Enrichment	LTBP4	0.75
986	Inherited isolated arrhythmogenic ventricular dysplasia, biventricular variant	Enrichment	TGFB3	0.75
987	Inherited isolated arrhythmogenic cardiomyopathy, dominant-left variant	Enrichment	TGFB3	0.75
988	Rheumatoid arthritis	Enrichment	CHRNG	0.74
989	Microcephaly	Enrichment	CTNNB1, GNAO1, IGF1R, MAPK1, PSMC3	0.74
990	Cataract 30, multiple types	Enrichment	VIM	0.74
991	Stroke, ischemic	Enrichment	PRKCH	0.74
992	Autosomal non-syndromic agammaglobulinemia	Enrichment	PIK3R1	0.74
993	Aortic valve disease 1	Enrichment	SOS1	0.71
994	Microphthalmia/coloboma 12	Enrichment	FZD5	0.71
995	Osteogenesis imperfecta, type iv	Enrichment	WNT1	0.71
996	Amelogenesis imperfecta	Enrichment	LTBP3	0.71
997	Chronic kidney disease	Enrichment	WNT9B	0.71
998	Protein-deficiency anemia	Enrichment	NRAS	0.71
999	Asthma	Enrichment	TNF	0.70
1000	Nemaline myopathy	Enrichment	ACTA1	0.70
1001	Hypotrichosis simplex	Enrichment	CDH3	0.70
1002	Hypogonadotropic hypogonadism 7 with or without anosmia	Enrichment	FGFR1	0.69
1003	Osteoporosis	Enrichment	WNT1	0.69
1004	Generalized epilepsy with febrile seizures plus	Enrichment	FGF13	0.69
1005	Cataract	Enrichment	EPHA2	0.69
1006	46,xy partial gonadal dysgenesis	Enrichment	SOS1	0.69
1007	Cerebral palsy	Enrichment	GNB1, PDGFRB	0.68
1008	Congenital hypothyroidism	Enrichment	TUBB1	0.67
1009	Early-onset parkinson's disease	Enrichment	SNCA	0.67
1010	Migraine with or without aura 1	Enrichment	ESR1	0.67
1011	Myelodysplastic syndrome	Enrichment	GNB1	0.67
1012	Myopathy	Enrichment	ACTA1, DNM2	0.66
1013	Omenn syndrome	Enrichment	PSMB10	0.66
1014	Polymicrogyria	Enrichment	PSMC3	0.66
1015	Coloboma of macula	Enrichment	FZD5	0.66
1016	Renal cell carcinoma, nonpapillary	Enrichment	MET	0.66
1017	Lynch syndrome	Enrichment	KRAS	0.66
1018	Chromosome 1p36 deletion syndrome	Enrichment	PRKCZ	0.64
1019	Congenital long qt syndrome	Enrichment	ITPR3	0.63
1020	Usher syndrome type 2	Enrichment	CDH23	0.62
1021	Movement disease	Enrichment	GNAO1	0.62
1022	Multiple sclerosis	Enrichment	TNFRSF1A	0.61
1023	Melanoma, cutaneous malignant 1	Enrichment	BRAF	0.61
1024	Cataract 44	Enrichment	EPHA2	0.61
1025	Polycystic liver disease	Enrichment	CTNNB1	0.61
1026	Autosomal dominant polycystic liver disease	Enrichment	CTNNB1	0.61
1027	Pulmonary disease, chronic obstructive	Enrichment	CHRNB4	0.60
1028	Acute promyelocytic leukemia	Enrichment	PRKAR1A	0.60
1029	Beckwith-wiedemann syndrome	Enrichment	IGF2	0.59
1030	Heart, malformation of	Enrichment	MAPK1	0.59
1031	Human immunodeficiency virus type 1	Enrichment	CXCL12	0.59
1032	Early-onset nuclear cataract	Enrichment	EPHA2	0.59
1033	Autosomal dominant polycystic kidney disease	Enrichment	TSC2	0.59
1034	Kidney disease	Enrichment	TSC1	0.59
1035	Autosomal dominant non-syndromic intellectual disability	Enrichment	ERBB4, YWHAZ	0.58
1036	Diffuse large b-cell lymphoma	Enrichment	BRAF	0.57
1037	Ehlers-danlos syndrome	Enrichment	TGFB2	0.57
1038	Premature menopause	Enrichment	EIF2B2	0.56
1039	Hypertelorism	Enrichment	FGFR2, RPS6KA3	0.56
1040	Congenital myopathy 4a, autosomal dominant	Enrichment	ACTA1	0.55
1041	Anterior segment dysgenesis	Enrichment	ITPR1	0.55
1042	Heart disease	Enrichment	CREBBP	0.53
1043	Wolff-parkinson-white syndrome	Enrichment	PRKAG2	0.53
1044	Visceral heterotaxy	Enrichment	LEFTY2	0.52
1045	Usher syndrome, type i	Enrichment	CDH23	0.51
1046	Cleft palate, isolated	Enrichment	GNB1	0.50
1047	Sudden infant death syndrome	Enrichment	CALM2	0.50
1048	Rare autosomal dominant non-syndromic sensorineural deafness type dfna	Enrichment	ACTG1, KITLG	0.50
1049	Precursor t-cell acute lymphoblastic leukemia	Enrichment	FLT3	0.50
1050	Behcet syndrome	Enrichment	TNFRSF1A	0.50
1051	Sensorineural hearing loss	Enrichment	CDH23, HGF	0.49
1052	Cardiomyopathy, familial hypertrophic, 1	Enrichment	RAF1	0.49
1053	Neuromuscular disease	Enrichment	ACTA1	0.48
1054	Focal segmental glomerulosclerosis	Enrichment	PLCE1	0.48
1055	Pancreatic cancer	Enrichment	KRAS	0.47
1056	Leber plus disease	Enrichment	CNGB3, GDF6, GUCY2D	0.46
1057	Lissencephaly	Enrichment	TUBG1	0.46
1058	Brugada syndrome	Enrichment	SEMA3A	0.46
1059	Complex neurodevelopmental disorder	Enrichment	AGO1, AGO2, CSNK2A1, PPP2CA	0.45
1060	Patent foramen ovale	Enrichment	PSMC3	0.45
1061	Early infantile developmental and epileptic encephalopathy	Enrichment	GNAO1	0.45
1062	Malaria	Enrichment	TNF	0.43
1063	Dilated cardiomyopathy	Enrichment	BRAF, RAF1	0.42
1064	Autoinflammatory disease	Enrichment	TNFRSF1A	0.42
1065	Attention deficit-hyperactivity disorder	Enrichment	GNB5	0.41
1066	Hereditary breast ovarian cancer syndrome	Enrichment	EIF2B5, KRAS	0.41
1067	Congenital stationary night blindness	Enrichment	GNB3	0.40
1068	Cystic fibrosis	Enrichment	TGFB1	0.39
1069	Scoliosis	Enrichment	CHRNG	0.39
1070	Familial hypertrophic cardiomyopathy	Enrichment	RAF1	0.38
1071	Left ventricular noncompaction	Enrichment	RAF1	0.36
1072	Ear malformation	Enrichment	CDH23	0.35
1073	Hereditary retinal dystrophy	Enrichment	CNGA1, CNGA3, CNGB1, CNGB3, GUCY2D, MERTK, TIMP3	0.35
1074	Fundus dystrophy	Enrichment	CNGA1, CNGA3, CNGB1, CNGB3, GUCY2D, MERTK, TIMP3	0.35
1075	Strabismus	Enrichment	GNB1	0.35
1076	Auditory neuropathy	Enrichment	CDH2	0.32
1077	Stargardt disease 1	Enrichment	CNGB3	0.31
1078	Retinitis pigmentosa	Enrichment	CNGA1, CNGB1, CNGB3, GUCY2D, MERTK	0.31
1079	Genetic steroid-resistant nephrotic syndrome	Enrichment	PLCE1	0.31
1080	Primary ciliary dyskinesia	Enrichment	DRC4, PRKAR1B	0.30
1081	Non-syndromic x-linked intellectual disability	Enrichment	RPS6KA3	0.29
1082	Dystonia	Enrichment	GNB1	0.27
1083	Systemic lupus erythematosus	Enrichment	TNF	0.27
1084	Non-syndromic genetic deafness	Enrichment	ACTG1	0.26
1085	Usher syndrome	Enrichment	CDH23	0.25
1086	Benign epilepsy with centrotemporal spikes	Enrichment	PLCB1	0.25
1087	Centralopathic epilepsy	Enrichment	PLCB1	0.24
1088	Nephrotic syndrome	Enrichment	PLCE1	0.24
1089	Familial isolated dilated cardiomyopathy	Enrichment	RAF1	0.23
1090	Developmental and epileptic encephalopathy	Enrichment	GNAO1	0.23
1091	Charcot-marie-tooth disease	Enrichment	DNM2	0.22
1092	Male infertility with azoospermia or oligozoospermia due to single gene mutation	Enrichment	FGF8	0.22
1093	Nonsyndromic hearing loss	Enrichment	ACTG1	0.22
1094	Hypertrophic cardiomyopathy	Enrichment	PRKAG2	0.21
1095	Autism spectrum disorder	Enrichment	MAP2K1, TSC2	0.19
1096	Spastic ataxia	Enrichment	ITPR1	0.16
1097	Mitochondrial disease	Enrichment	GFER	0.12
1098	Deafness, autosomal recessive	Enrichment	CDH23	0.10
1099	Autosomal recessive nonsyndromic deafness	Enrichment	CDH23	0.10
1100	Autism	Enrichment	CHRNA1	0.10
1101	Rare genetic deafness	Enrichment	ACTG1	0.08

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Nanog in Mammalian ESC Pluripotency

Pathway Network for Nanog in Mammalian ESC Pluripotency

Pathway network for the Nanog in Mammalian ESC Pluripotency SuperPath

Member Pathways for Nanog in Mammalian ESC Pluripotency

Pathways in the Nanog in Mammalian ESC Pluripotency SuperPath

Gene overlap in member pathways for Nanog in Mammalian ESC Pluripotency SuperPath

Associated Genes for Nanog in Mammalian ESC Pluripotency

Associated Disorders for Nanog in Mammalian ESC Pluripotency

Disorders associated with Nanog in Mammalian ESC Pluripotency SuperPath

STRING Interaction Network for Nanog in Mammalian ESC Pluripotency

Sources for Nanog in Mammalian ESC Pluripotency