Naphthalene metabolism

No Pathway Network information available for Naphthalene metabolism

#	Name	Source	Genes
1	Naphthalene metabolism	GeneGo (Thomson Reuters)	ACYP1 AKR1A1 AKR1B1 AKR1C1 AKR1C2 AKR1C3 AKR1C4 AKR7A2 CYP1A1 CYP1A2 CYP2A6 CYP2C8 CYP2C9 CYP2E1 CYP2F1 CYP2S1 CYP3A4 EPHX1 EPHX2 GSTA1 GSTA2 GSTM1 GSTP1 GSTT1 (see all 24) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	ACYP1	Acylphosphatase 1	Protein Coding	1
2	AKR1B1	Aldo-Keto Reductase Family 1 Member B	Protein Coding	1
3	AKR1C4	Aldo-Keto Reductase Family 1 Member C4	Protein Coding	1
4	CYP1A1	Cytochrome P450 Family 1 Subfamily A Member 1	Protein Coding	1
5	CYP1A2	Cytochrome P450 Family 1 Subfamily A Member 2	Protein Coding	1
6	CYP2A6	Cytochrome P450 Family 2 Subfamily A Member 6	Protein Coding	1
7	CYP2C8	Cytochrome P450 Family 2 Subfamily C Member 8	Protein Coding	1
8	CYP2C9	Cytochrome P450 Family 2 Subfamily C Member 9	Protein Coding	1
9	CYP2E1	Cytochrome P450 Family 2 Subfamily E Member 1	Protein Coding	1
10	CYP2F1	Cytochrome P450 Family 2 Subfamily F Member 1	Protein Coding	1
11	CYP3A4	Cytochrome P450 Family 3 Subfamily A Member 4	Protein Coding	1
12	AKR1C1	Aldo-Keto Reductase Family 1 Member C1	Protein Coding	1
13	AKR1C2	Aldo-Keto Reductase Family 1 Member C2	Protein Coding	1
14	EPHX1	Epoxide Hydrolase 1	Protein Coding	1
15	EPHX2	Epoxide Hydrolase 2	Protein Coding	1
16	GSTA1	Glutathione S-Transferase Alpha 1	Protein Coding	1
17	GSTA2	Glutathione S-Transferase Alpha 2	Protein Coding	1
18	GSTM1	Glutathione S-Transferase Mu 1	Protein Coding	1
19	GSTP1	Glutathione S-Transferase Pi 1	Protein Coding	1
20	GSTT1	Glutathione S-Transferase Theta 1	Protein Coding	1
21	AKR7A2	Aldo-Keto Reductase Family 7 Member A2	Protein Coding	1
22	AKR1C3	Aldo-Keto Reductase Family 1 Member C3	Protein Coding	1
23	AKR1A1	Aldo-Keto Reductase Family 1 Member A1	Protein Coding	1
24	CYP2S1	Cytochrome P450 Family 2 Subfamily S Member 1	Protein Coding	1

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Coumarin resistance	Enrichment	CYP2A6, CYP2C9	5.05
2	46,xy sex reversal 8	Enrichment	AKR1C2, AKR1C4	5.05
3	Drug metabolism, altered, cyp2c8-related	Enrichment	CYP2C8	2.75
4	Vitamin d-dependent rickets, type 3	Enrichment	CYP3A4	2.75
5	Genetic lipodystrophy	Enrichment	EPHX1	2.75
6	Letrozole toxicity	Enrichment	CYP2A6	2.75
7	Kala-azar 2	Enrichment	GSTP1	2.45
8	Cic-rearranged sarcoma	Enrichment	AKR1C2	2.45
9	Tobacco addiction	Enrichment	CYP2A6	2.15
10	Developmental dysplasia of the hip 1	Enrichment	AKR1C1	1.98
11	Familial hypercholanemia	Enrichment	EPHX1	1.98
12	Hypercholesterolemia, familial, 1	Enrichment	EPHX2	1.64
13	Familial hypercholesterolemia	Enrichment	EPHX2	1.58
14	Lung cancer	Enrichment	CYP2A6	1.26
15	Cystic fibrosis	Enrichment	EPHX1	1.26
16	Microcephaly	Enrichment	ACYP1	0.71

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Pathway Network for Naphthalene metabolism