ncRNAs involved in Wnt signaling in hepatocellular carcinoma

Pathway network for the ncRNAs involved in Wnt signaling in hepatocellular carcinoma SuperPath

Sources:
  • WikiPathways
  • R&D Systems

Pathways in the ncRNAs involved in Wnt signaling in hepatocellular carcinoma SuperPath

#NameSourceGenes
1ncRNAs involved in Wnt signaling in hepatocellular carcinomaWikiPathways
2Wnt Signaling PathwaysR&D Systems
3Wnt signalingWikiPathways
4Wnt signaling pathway and pluripotencyWikiPathways
5lncRNA in canonical Wnt signaling and colorectal cancerWikiPathways

Gene overlap in member pathways for ncRNAs involved in Wnt signaling in hepatocellular carcinoma SuperPath

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

Disorders associated with ncRNAs involved in Wnt signaling in hepatocellular carcinoma SuperPath

according to GeneCards Suite gene sharing
#DisorderTypeGenesScore
1Robinow syndrome, autosomal recessive 1EnrichmentDVL1, DVL3, FZD2, ROR2, WNT5A10.79
2Autosomal recessive robinow syndromeEnrichmentDVL1, DVL3, FZD2, ROR2, WNT5A10.17
3Robinow syndrome, autosomal dominant 1EnrichmentDVL1, DVL3, FZD2, WNT5A8.78
4Autosomal dominant robinow syndromeEnrichmentDVL1, DVL3, FZD2, WNT5A8.78
5Osteoporosis, juvenileEnrichmentDKK1, WNT1, WNT3A6.58
6Robinow syndrome, autosomal dominant 2EnrichmentDVL1, DVL3, FZD25.58
7Colorectal cancerEnrichmentAPC, AXIN2, CCND1, CTNNB1, EP300, FZD3, TP535.43
8Exudative vitreoretinopathy 1EnrichmentCTNNB1, FZD4, LRP55.40
9Polycystic liver diseaseEnrichmentCTNNB1, LRP5, LRP6, RUVBL15.26
10Autosomal dominant polycystic liver diseaseEnrichmentCTNNB1, LRP5, LRP6, RUVBL15.26
11Tooth agenesisEnrichmentAXIN2, LRP6, WNT10A, WNT10B4.79
12Hepatocellular carcinomaEnrichmentAPC, AXIN1, CTNNB1, TP534.72
13Exudative vitreoretinopathyEnrichmentCTNNB1, FZD4, LRP54.66
14Adult hepatocellular carcinomaEnrichmentAXIN1, CTNNB1, TP534.49
15Van buchem diseaseEnrichmentLRP5, SOST4.38
16Robinow syndrome, autosomal dominant 3EnrichmentDVL3, FZD24.38
17Autosomal dominant non-syndromic intellectual disabilityEnrichmentCAMK2A, CAMK2B, CSNK2B, PPP3CA, PRICKLE24.22
18Desmoid disease, hereditaryEnrichmentAPC, CTNNB13.91
19Desmoid tumorEnrichmentAPC, CTNNB13.91
20OsteoporosisEnrichmentLRP5, SRC, WNT13.71
21CraniopharyngiomaEnrichmentAPC, CTNNB13.61
22Retinopathy of prematurityEnrichmentFZD4, LRP53.49
23Brittle bone disorderEnrichmentLRP5, SERPINF1, WNT13.37
24HepatoblastomaEnrichmentAPC, CTNNB1, TP533.32
25Rubinstein-taybi syndrome 1EnrichmentCREBBP, EP3003.09
26Chromosome 16p13.3 deletion syndrome, proximalEnrichmentCREBBP, EP3003.09
27Adrenocortical carcinomaEnrichmentCTNNB1, TP533.09
28Gallbladder cancerEnrichmentCTNNB1, TP532.95
29Isolated split hand-split foot malformationEnrichmentBTRC, WNT10B2.72
30Cat eye syndromeEnrichmentFZD5, TFAP2A2.66
31Leukemia, chronic lymphocyticEnrichmentCCND1, TP532.62
32Osteogenesis imperfecta, type ivEnrichmentSERPINF1, WNT12.51
33MedulloblastomaEnrichmentAPC, CTNNB12.44
34Osteogenesis imperfecta, type iiiEnrichmentSERPINF1, WNT12.38
35Neural tube defectsEnrichmentVANGL1, VANGL22.29
36Rare genetic intellectual disabilityEnrichmentCREBBP, EP3002.27
37Brachydactyly, type b1EnrichmentROR22.19
38Chiari malformation type iEnrichmentDKK12.19
39Endosteal hyperostosis, autosomal dominantEnrichmentLRP52.19
40Craniodiaphyseal dysplasia, autosomal dominantEnrichmentSOST2.19
41Nail disorder, nonsyndromic congenital, 1EnrichmentFZD62.19
42Mullerian aplasia and hyperandrogenismEnrichmentWNT42.19
43Bone mineral density quantitative trait locus 1EnrichmentLRP52.19
44Exudative vitreoretinopathy 4EnrichmentLRP52.19
45Sclerosteosis 1EnrichmentSOST2.19
46Focal dermal hypoplasiaEnrichmentPORCN2.19
4746,xx sex reversal with dysgenesis of kidneys, adrenals, and lungsEnrichmentWNT42.19
48Omodysplasia 2EnrichmentFZD22.19
49Megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome 3EnrichmentCCND22.19
50Split-hand/foot malformation 6EnrichmentWNT10B2.19
51Tooth agenesis, selective, 7EnrichmentLRP62.19
52Caudal duplication anomalyEnrichmentAXIN12.19
53Tooth agenesis, selective, 8EnrichmentWNT10B2.19
54Vesicoureteral reflux 3EnrichmentSOX172.19
55Ectodermal dysplasia 13, hair/tooth typeEnrichmentKREMEN12.19
56Ectodermal dysplasia 17 with or without limb malformationsEnrichmentLEF12.19
57Exudative vitreoretinopathy 8EnrichmentLRP62.19
58Pyle diseaseEnrichmentSFRP42.19
59Deafness, autosomal recessive 108EnrichmentROR12.19
60Diarrhea 9EnrichmentWNT2B2.19
61Osteoporosis-pseudoglioma syndromeEnrichmentLRP52.19
62Coronary artery disease, autosomal dominant 2EnrichmentLRP62.19
63Bone mineral density quantitative trait locus 16EnrichmentWNT12.19
64Polycystic liver disease 4 with or without kidney cystsEnrichmentLRP52.19
65Santos syndromeEnrichmentWNT7A2.19
66Microphthalmia/coloboma 11EnrichmentFZD52.19
67Okur-chung neurodevelopmental syndromeEnrichmentCSNK2A12.19
68Craniometadiaphyseal osteosclerosis with hip dysplasiaEnrichmentAXIN12.19
69Adenoid ameloblastomaEnrichmentCTNNB12.19
70Craniodigital syndrome and intellectual disability syndromeEnrichmentCSNK2B2.19
71Lrp5-related primary osteoporosisEnrichmentLRP52.19
72Pulmonary hypertension, primary, 7EnrichmentSOX172.19
73Familial adenomatous polyposisEnrichmentAPC2.19
74Gardner syndromeEnrichmentAPC2.19
75Osteosclerosis-developmental delay-craniosynostosis syndromeEnrichmentLRP52.19
765q22 microdeletion syndromeEnrichmentAPC2.19
77Attenuated familial adenomatous polyposisEnrichmentAPC2.19
78Microcystic stromal tumorEnrichmentCTNNB12.19
79Ovarian cancerEnrichmentAPC, AXIN2, CTNNB1, TP532.17
80Cardiospondylocarpofacial syndromeEnrichmentMAP3K72.15
81Oligodontia-colorectal cancer syndromeEnrichmentAXIN22.15
82Microcephaly 12, primary, autosomal recessiveEnrichmentCDK62.15
83Frontometaphyseal dysplasia 2EnrichmentMAP3K72.15
84Agammaglobulinemia 8b, autosomal recessiveEnrichmentTCF32.15
85Cortical dysplasia, complex, with other brain malformations 10EnrichmentAPC22.15
86Developmental and epileptic encephalopathy 54EnrichmentHNRNPU2.15
87Intellectual developmental disorder, autosomal recessive 74EnrichmentAPC22.15
88Agammaglobulinemia 8a, autosomal dominantEnrichmentTCF32.15
89Sotos syndrome 3EnrichmentAPC22.15
90Beckwith-wiedemann syndrome due to 11p15 microdeletionEnrichmentH192.15
911q44 microdeletion syndromeEnrichmentHNRNPU2.15
92Macs syndromeEnrichmentPORCN, WNT7B2.14
93Spinocerebellar ataxia 12EnrichmentPPP2R2B2.13
94Autoimmune lymphoproliferative syndrome, type iiiEnrichmentPRKCD2.13
95Parkinson disease 25, autosomal recessive early-onset, with impaired intellectual developmentEnrichmentPTPA2.13
96Bone marrow failure syndrome 5EnrichmentTP532.13
97Houge-janssens syndrome 4EnrichmentPPP2R5C2.13
98Papilloma of choroid plexusEnrichmentTP532.13
99Basal cell carcinoma 7EnrichmentTP532.13
100Anaplastic thyroid carcinomaEnrichmentTP532.13
101Houge-janssens syndrome 2EnrichmentPPP2R1A2.13
102Spinocerebellar ataxia 14EnrichmentPRKCG2.13
103Deafness, autosomal recessive 35EnrichmentESRRB2.13
104Ductal carcinoma in situEnrichmentTP532.13
105Congenital heart defects and ectodermal dysplasiaEnrichmentPRKD12.13
106Ectodermal dysplasia with facial dysmorphism and acral, ocular, and brain anomaliesEnrichmentRHOA2.13
107Menke-hennekam syndrome 1EnrichmentCREBBP2.13
108Linear hypopigmentation and craniofacial asymmetry with acral, ocular and brain anomaliesEnrichmentRHOA2.13
109Thyroid gland undifferentiated carcinomaEnrichmentTP532.13
110Small-cell carcinoma of the ovary of hypercalcemic typeEnrichmentTP532.13
111Rubinstein-taybi syndrome due to 16p13.3 microdeletionEnrichmentCREBBP2.13
112Diffuse pediatric-type high-grade glioma, h3-wildtype and idh-wildtypeEnrichmentTP532.13
113Congenital dyserythropoietic anemia type iiibEnrichmentRACGAP12.13
114Choroid plexus cancerEnrichmentTP532.13
115Menke-hennekam syndromeEnrichmentCREBBP2.13
116Pleomorphic xanthoastrocytomaEnrichmentTP532.13
117Anemia, congenital dyserythropoietic, type iiib, autosomal recessiveEnrichmentRACGAP12.13
118Lissencephaly due to lis1 mutationEnrichmentPAFAH1B12.13
119Ppp2r1a-related neurodevelopmental disorderEnrichmentPPP2R1A2.13
120Malignant epithelial tumor of salivary glandsEnrichmentPRKD12.13
121Myeloma, multipleEnrichmentCCND1, CREBBP, TP532.08
122Immunodeficiency 73a with defective neutrophil chemotaxis and leukocytosisEnrichmentRAC22.08
123Advanced sleep phase syndrome, familial, 2EnrichmentCSNK1D2.08
124Bone mineral density quantitative trait locus 17EnrichmentLGR42.08
125Spondylometaphyseal dysplasia with corneal dystrophyEnrichmentPLCB32.08
126Intellectual developmental disorder, autosomal recessive 63EnrichmentCAMK2A2.08
127Developmental and epileptic encephalopathy 91EnrichmentPPP3CA2.08
128Neurodevelopmental disorder with structural brain anomalies and dysmorphic faciesEnrichmentRAC32.08
129Intellectual developmental disorder, autosomal dominant 54EnrichmentCAMK2B2.08
130Arthrogryposis, cleft palate, craniosynostosis, and impaired intellectual developmentEnrichmentPPP3CA2.08
131Humerofemoral hypoplasia with radiotibial ray deficiencyEnrichmentRSPO22.08
132Auriculocondylar syndrome 2aEnrichmentPLCB42.08
133Immunodeficiency 73c with defective neutrophil chemotaxis and hypogammaglobulinemiaEnrichmentRAC22.08
134Palmoplantar hyperkeratosis with squamous cell carcinoma of skin and 46,xx sex reversalEnrichmentRSPO12.08
135Oocyte/zygote/embryo maturation arrest 15EnrichmentTLE62.08
136Thrombocytopenia 6EnrichmentSRC2.08
137Tetraamelia syndrome 2EnrichmentRSPO22.08
138Intellectual developmental disorder, autosomal dominant 53EnrichmentCAMK2A2.08
139Immunodeficiency 73b with defective neutrophil chemotaxis and lymphopeniaEnrichmentRAC22.08
140Auriculocondylar syndrome 2bEnrichmentPLCB42.08
141Intellectual developmental disorder, autosomal dominant 59EnrichmentCAMK2G2.08
142Palmoplantar keratoderma-xx sex reversal-predisposition to squamous cell carcinoma syndromeEnrichmentRSPO12.08
143Infantile lad-like disease due to rac2 deficiencyEnrichmentRAC22.08
144Reticular dysgenesis-like severe combined immunodeficiencyEnrichmentRAC22.08
145Microcephaly-corpus callosum and cerebellar vermis hypoplasia-facial dysmorphism-intellectual disability syndromEnrichmentRAC12.08
146Rac2-related combined immunodeficiency-bronchiectasis-cancer-predisposing syndromeEnrichmentRAC22.08
147Keipert syndromeEnrichmentGPC42.08
148Diffuse large b-cell lymphomaEnrichmentCREBBP, TP532.06
149MicrophthalmiaEnrichmentTFAP2A, WNT7B1.97
150Ectrodactyly and ectodermal dysplasia without cleft lip/palateEnrichmentLEF11.89
151Burkitt lymphomaEnrichmentMYC1.89
152Tooth agenesis, selective, 4EnrichmentWNT10A1.89
153Craniodiaphyseal dysplasiaEnrichmentSOST1.89
154Schopf-schulz-passarge syndromeEnrichmentWNT10A1.89
155Ulna and fibula, absence of, with severe limb deficiencyEnrichmentWNT7A1.89
156Bladder exstrophy and epispadias complexEnrichmentWNT31.89
157Osteopathia striata with cranial sclerosisEnrichmentCTNNB11.89
158Quebec platelet disorderEnrichmentPLAU1.89
159Odontoonychodermal dysplasiaEnrichmentWNT10A1.89
160Tetraamelia syndrome 1EnrichmentWNT31.89
161Osteogenesis imperfecta, type xvEnrichmentWNT11.89
162Fibular aplasia or hypoplasia, femoral bowing, and poly-, syn-, and oligodactylyEnrichmentWNT7A1.89
163Hypotonia, ataxia, developmental delay, and tooth enamel defect syndromeEnrichmentCTBP11.89
164Poirier-bienvenu neurodevelopmental syndromeEnrichmentCSNK2B1.89
165SclerosteosisEnrichmentSOST1.89
166Childhood hepatocellular carcinomaEnrichmentCTNNB11.89
167Split hand-foot malformationEnrichmentLEF11.89
168Periampullary adenomaEnrichmentAPC1.89
169Gastric adenocarcinoma and proximal polyposis of the stomachEnrichmentAPC1.89
17014q11.2 microduplication syndromeEnrichmentCHD81.89
171Juvenile nasopharyngeal angiofibromaEnrichmentCTNNB11.89
172TeratomaEnrichmentCTNNB11.89
173OsteosclerosisEnrichmentLRP51.89
174Bladder exstrophy-epispadias-cloacal exstrophy complexEnrichmentWNT31.89
175Ebstein anomalyEnrichmentCDK81.85
176Immunodeficiency, common variable, 15EnrichmentRUVBL11.85
177EsotropiaEnrichmentTFAP2A1.85
178Intellectual developmental disorder with hypotonia and behavioral abnormalitiesEnrichmentCDK81.85
179B-lymphoblastic leukemia/lymphoma with t(1;19)(q23;p13.3)EnrichmentTCF31.85
180B-lymphoblastic leukemia/lymphoma with t(17;19)EnrichmentTCF31.85
181Lens subluxationEnrichmentTFAP2A1.85
182Silver-russell syndrome due to an imprinting defect of 11p15EnrichmentH191.85
183Silver-russell syndrome due to 11p15 microduplicationEnrichmentH191.85
184Blepharocheilodontic syndrome 1EnrichmentCTNND11.83
185Anemia, congenital dyserythropoietic, type iiiaEnrichmentRACGAP11.83
186Adrenocortical carcinoma, hereditaryEnrichmentTP531.83
187Thumb deformityEnrichmentCREBBP1.83
188Cervical cancerEnrichmentTP531.83
189Parkinson disease 8, autosomal dominantEnrichmentLRRK21.83
190Lissencephaly 1EnrichmentPAFAH1B11.83
191Lymphoma, hodgkin, classicEnrichmentTP531.83
192Blepharocheilodontic syndrome 2EnrichmentCTNND11.83
193Menke-hennekam syndrome 2EnrichmentEP3001.83
194Hyperlipoproteinemia, type iiiEnrichmentLDLR1.83
195Acute myeloid leukemia with kat6a-crebbp fusionEnrichmentCREBBP1.83
196Congenital fibrosarcomaEnrichmentTP531.83
197Li-fraumeni syndrome 1EnrichmentTP531.83
198SarcomaEnrichmentTP531.83
199Cervix carcinomaEnrichmentTP531.83
200Hodgkin's lymphomaEnrichmentTP531.83
201Houge-janssens syndrome 3EnrichmentPPP2CA1.83
202Pleomorphic rhabdomyosarcomaEnrichmentTP531.83
203Omodysplasia 1EnrichmentGPC61.78
204Intellectual developmental disorder, autosomal dominant 48EnrichmentRAC11.78
205Delayed puberty, self-limitedEnrichmentLGR41.78
206Ocular melanomaEnrichmentPLCB41.78
207Joint contractures, osteochondromas, and b-cell lymphomaEnrichmentNFATC21.78
208Isolated anencephalyEnrichmentVANGL21.78
209Isolated exencephalyEnrichmentVANGL21.78
210Breast cancerEnrichmentAPC, JUN, TP531.74
211Prognathism, mandibularEnrichmentCSNK2B1.71
212Mullerian duct aplasia, unilateral renal agenesis, and cervicothoracic somite anomaliesEnrichmentWNT41.71
213Microphthalmia, syndromic 9EnrichmentWNT7B1.71
214Weaver syndromeEnrichmentEZH21.71
215Tooth agenesis, selective, 2EnrichmentWNT10A1.71
216Osteopetrosis, autosomal dominant 1EnrichmentLRP51.71
217Neurodevelopmental disorder with spastic diplegia and visual defectsEnrichmentCTNNB11.71
218Cenani-lenz syndactyly syndromeEnrichmentAPC1.71
219Osteogenesis imperfecta, type viEnrichmentSERPINF11.71
220Anus, imperforateEnrichmentCTNNB11.71
221Exudative vitreoretinopathy 7EnrichmentCTNNB11.71
222High-grade b-cell lymphoma double-hit/triple-hitEnrichmentMYC1.71
223Nail diseaseEnrichmentFZD61.71
224Familial vesicoureteral refluxEnrichmentSOX171.71
225Tetraamelia syndromeEnrichmentWNT31.71
226Colon adenocarcinomaEnrichmentAPC1.71
227Apc-associated polyposis conditionsEnrichmentAPC1.71
228Bladder cancerEnrichmentCTNNB1, TP531.71
229Neurodevelopmental disorder with progressive spasticity and brain abnormalitiesEnrichmentRUVBL11.67
230Frontometaphyseal dysplasiaEnrichmentMAP3K71.67
231Beckwith-wiedemann syndrome due to imprinting defect of 11p15EnrichmentH191.67
232Hypercholesterolemia, familial, 2EnrichmentLDLR1.65
233Klippel-feil syndrome 1, autosomal dominantEnrichmentLRRK21.65
234Intellectual developmental disorder with microcephaly and pontine and cerebellar hypoplasiaEnrichmentLDLR1.65
235Band heterotopiaEnrichmentPAFAH1B11.65
236Autoimmune disease 1EnrichmentFOXD31.65
237Osteogenic sarcomaEnrichmentTP531.65
238Hypercholesterolemia, familial, 4EnrichmentLDLR1.65
239Nasopharyngeal carcinomaEnrichmentTP531.65
240Miller-dieker lissencephaly syndromeEnrichmentPAFAH1B11.65
241Chromosome 17p13.3, centromeric, duplication syndromeEnrichmentPAFAH1B11.65
242Tethered spinal cord syndromeEnrichmentCREBBP1.65
243Syndromic x-linked intellectual disability najm typeEnrichmentLDLR1.65
244Atypical teratoid rhabdoid tumorEnrichmentTP531.65
245Anaplastic astrocytomaEnrichmentTP531.65
246Squamous cell carcinomaEnrichmentTP531.65
247AdenocarcinomaEnrichmentTP531.65
248Intraocular pressure quantitative trait locusEnrichmentCREBBP1.65
249Bone osteosarcomaEnrichmentTP531.65
250AutismEnrichmentCAMK2G, CHD8, TCF7L21.64
251Nail disorder, nonsyndromic congenital, 4EnrichmentRSPO41.60
252Simpson-golabi-behmel syndrome, type 1EnrichmentGPC31.60
253Advanced sleep phase syndromeEnrichmentCSNK1D1.60
254Nephronophthisis 2EnrichmentINVS1.60
255Epilepsy, progressive myoclonic, 1bEnrichmentPRICKLE11.60
256Nephrotic syndrome, type 24EnrichmentDAAM21.60
257Acyl-coa dehydrogenase, very long-chain, deficiency ofEnrichmentDVL21.59
258Ectodermal dysplasia 10b, hypohidrotic/hair/tooth type, autosomal recessiveEnrichmentWNT10A1.59
259Megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome 1EnrichmentCCND21.59
260PilomatrixomaEnrichmentCTNNB11.59
261Alazami syndromeEnrichmentCTNNB11.59
262Mantle cell lymphomaEnrichmentCCND11.59
263EnophthalmosEnrichmentCSNK2B1.59
264SyndactylyEnrichmentCSNK2B1.59
265Intellectual developmental disorder with autism and macrocephalyEnrichmentCHD81.59
266Orofacial cleftEnrichmentLRP61.59
267Ectodermal dysplasiaEnrichmentWNT10A1.59
268Eyelid colobomaEnrichmentFZD51.59
269VitreoretinopathyEnrichmentLRP51.59
270Orofacial clefting syndromeEnrichmentLRP61.59
271Lens colobomaEnrichmentFZD51.59
272Branchiooculofacial syndromeEnrichmentTFAP2A1.55
273Au-kline syndromeEnrichmentHNRNPK1.55
274Small cell cancer of the lungEnrichmentTP531.53
275Microphthalmia, syndromic 3EnrichmentSOX21.53
276Thyroid cancer, nonmedullary, 1EnrichmentTP531.53
277Lung sarcomatoid carcinomaEnrichmentTP531.53
278Hereditary ataxiaEnrichmentPRKCG1.53
279Embryonal rhabdomyosarcomaEnrichmentTP531.53
280Distal arthrogryposisEnrichmentFZD3, ROR21.52
281Alzheimer disease 2EnrichmentPLAU1.49
282Von hippel-lindau syndromeEnrichmentCCND11.49
283Familial adenomatous polyposis 1EnrichmentAPC1.49
284Congenital ptosisEnrichmentCHD81.49
285Autosomal recessive hypohidrotic ectodermal dysplasia syndromeEnrichmentWNT10A1.49
286Coloboma of choroid and retinaEnrichmentFZD51.49
287Auriculocondylar syndrome 1EnrichmentPLCB41.48
288Developmental and epileptic encephalopathy 12EnrichmentPLCB11.48
289Sacral defect with anterior meningoceleEnrichmentVANGL11.48
290Autism spectrum disorderEnrichmentCHD8, CSNK2A1, CSNK2B1.47
291Sotos syndromeEnrichmentAPC21.45
292AmblyopiaEnrichmentTFAP2A1.45
293Hyperlipidemia, familial combined, 3EnrichmentLDLR1.44
294Norrie diseaseEnrichmentFZD41.44
295Rhabdomyosarcoma 2EnrichmentTP531.44
296Chromosome 15q11.2 deletion syndromeEnrichmentPAFAH1B11.44
297Rubinstein-taybi syndrome 2EnrichmentEP3001.44
298LymphomaEnrichmentTP531.44
299Persistent hyperplastic primary vitreousEnrichmentFZD41.44
300Acute megakaryocytic leukemiaEnrichmentTP531.44
301Coloboma of optic nerveEnrichmentFZD51.42
302Weyers acrofacial dysostosisEnrichmentCTNNB11.42
303Wolf-hirschhorn syndromeEnrichmentCTBP11.42
304Split-hand/foot malformation 1EnrichmentLEF11.42
305DiarrheaEnrichmentWNT2B1.42
306Multicystic kidney dysplasiaEnrichmentFZD31.42
307Multicystic dysplastic kidneyEnrichmentFZD31.42
308Gastric cancerEnrichmentAPC, TP531.39
309Female infertility due to oocyte meiotic arrestEnrichmentTLE61.38
310Sensory ataxic neuropathy, dysarthria, and ophthalmoparesisEnrichmentPRICKLE21.38
311Branchiootorenal syndrome 1EnrichmentTFAP2A1.38
312Hemihyperplasia, isolatedEnrichmentH191.38
313Hereditary breast carcinomaEnrichmentAPC, TP531.37
314Li-fraumeni syndromeEnrichmentTP531.36
315Machado-joseph diseaseEnrichmentLRRK21.36
316Cowden syndrome 1EnrichmentLDLR1.36
317Renal dysplasia, cysticEnrichmentWNT9B1.36
318Renal hypoplasiaEnrichmentWNT9B1.36
319Lipid metabolism disorderEnrichmentLDLR1.36
320Breast adenocarcinomaEnrichmentTP531.36
321HypertrichosisEnrichmentCREBBP1.36
322Cleft lip with or without cleft palateEnrichmentCTNND11.36
323Overgrowth syndromeEnrichmentCHD81.35
324Benign epilepsy with centrotemporal spikesEnrichmentPRICKLE1, PRICKLE21.33
325Branchiootorenal syndromeEnrichmentTFAP2A1.31
326Melanoma, uvealEnrichmentPLCB41.31
327Centralopathic epilepsyEnrichmentPRICKLE1, PRICKLE21.30
328Esophageal cancerEnrichmentTP531.29
329Squamous cell carcinoma, head and neckEnrichmentTP531.29
330Coats diseaseEnrichmentFZD41.29
331Essential thrombocythemiaEnrichmentTP531.29
332B-lymphoblastic leukemia/lymphoma with t(9;22)(q34.1;q11.2)EnrichmentTP531.29
333West syndromeEnrichmentCSNK1E, PLCB11.28
334Colonic benign neoplasmEnrichmentAPC1.24
335MyelofibrosisEnrichmentSRC1.24
336Glioma susceptibility 1EnrichmentTP531.24
337Renal hypodysplasia/aplasia 1EnrichmentWNT9B1.24
338Lymphoma, non-hodgkin, familialEnrichmentTP531.24
339Lennox-gastaut syndromeEnrichmentMAPK101.24
340Homozygous familial hypercholesterolemiaEnrichmentLDLR1.24
341Complex neurodevelopmental disorderEnrichmentCDK8, CSNK2A1, TCF7L21.23
342Tooth agenesis, selective, 1EnrichmentAXIN21.20
343Tracheoesophageal fistula with or without esophageal atresiaEnrichmentAPC21.20
344Charge syndromeEnrichmentEP3001.19
345Inflammatory bowel disease 1EnrichmentPRKCQ1.19
346Coronary heart disease 5EnrichmentLDLR1.19
347Primary hyperaldosteronismEnrichmentTP531.19
348Autosomal dominant cerebellar ataxiaEnrichmentLRRK21.19
349Renal agenesis, bilateralEnrichmentWNT9B1.19
350Infantile nephronophthisisEnrichmentINVS1.19
351Inherited cancer-predisposing syndromeEnrichmentAPC, AXIN2, EZH21.16
352Heritable pulmonary arterial hypertensionEnrichmentSOX171.16
353Isolated tracheo-esophageal fistulaEnrichmentAPC21.16
354Autosomal non-syndromic agammaglobulinemiaEnrichmentTCF31.16
355Stroke, ischemicEnrichmentPRKCH1.14
356Familial colorectal cancerEnrichmentTP531.14
357Developmental and epileptic encephalopathy 14EnrichmentPLCB11.14
358Neurodevelopmental disorder with dysmorphic facies and distal limb anomaliesEnrichmentRAC11.14
359Myelodysplastic syndromeEnrichmentTP531.10
360NanophthalmosEnrichmentSOX21.10
361Microphthalmia/coloboma 12EnrichmentFZD51.09
362Pulmonary hypertension, primary, 1EnrichmentSOX171.09
363EpicanthusEnrichmentTFAP2A1.08
364Septooptic dysplasiaEnrichmentSOX21.07
365Early-onset parkinson's diseaseEnrichmentLRRK21.07
366Lip and oral cavity carcinomaEnrichmentTP531.07
367Diaphragmatic hernia, congenitalEnrichmentCDK81.05
368Hypercholesterolemia, familial, 1EnrichmentLDLR1.03
369Chromosome 1p36 deletion syndromeEnrichmentPRKCZ1.03
370Chronic kidney diseaseEnrichmentWNT9B1.03
371Coloboma of maculaEnrichmentFZD51.03
372HydrocephalusEnrichmentFZD31.03
373Lung cancer susceptibility 3EnrichmentTP531.00
374Heart diseaseEnrichmentCREBBP1.00
375Wilms tumor 1EnrichmentH190.99
376Senior-loken syndrome 1EnrichmentINVS0.98
377Alzheimer disease, familial, 1EnrichmentPLAU0.98
378Polydactyly, postaxial, type a1EnrichmentEP3000.97
379Corpus callosum, agenesis ofEnrichmentCREBBP0.97
380Familial hypercholesterolemiaEnrichmentLDLR0.97
381Isolated corpus callosum agenesisEnrichmentCREBBP0.97
382Intellectual disability-hypoplastic corpus callosum-preauricular tag syndromeEnrichmentCREBBP0.97
383Hydrocephalus, congenital, 1EnrichmentCDK80.96
384Myoclonic epilepsy of unverricht and lundborgEnrichmentPRICKLE10.95
385RhabdomyosarcomaEnrichmentTP530.95
386GliosarcomaEnrichmentTP530.95
387Giant cell glioblastomaEnrichmentTP530.92
388Heart, malformation ofEnrichmentCDK80.92
389Esophageal atresia/tracheoesophageal fistulaEnrichmentAPC20.89
390Parkinson's diseaseEnrichmentLRRK20.88
391Precursor t-cell acute lymphoblastic leukemiaEnrichmentMYC0.86
392LissencephalyEnrichmentPAFAH1B10.84
393Developmental and epileptic encephalopathy 1EnrichmentCSNK1E0.82
394CraniosynostosisEnrichmentGPC40.81
395Hydrops fetalis, nonimmuneEnrichmentFZD60.81
396Diamond-blackfan anemia 1EnrichmentTP530.80
397Cardiomyopathy, dilated, 1aEnrichmentNFATC20.79
398Parkinson disease, late-onsetEnrichmentLRRK20.78
399ScoliosisEnrichmentCREBBP0.78
400Pancreatic cancerEnrichmentTP530.77
401Non-immune hydrops fetalisEnrichmentFZD60.74
402Congenital nervous system abnormalityEnrichmentCREBBP, CTNNB10.73
403Nervous system diseaseEnrichmentCREBBP, CTNNB10.73
404Hirschsprung disease 1EnrichmentAXIN20.73
405Prostate cancerEnrichmentTP530.71
406Primary autosomal recessive microcephalyEnrichmentCDK60.69
407Lung cancerEnrichmentPPP2R1B0.67
408Fetal akinesia deformation sequence 1EnrichmentROR20.67
409MicrocephalyEnrichmentCTNNB1, EP3000.63
410Diamond-blackfan anemiaEnrichmentTP530.63
411Type 2 diabetes mellitusEnrichmentTCF7L20.62
412NephronophthisisEnrichmentINVS0.61
413Genetic steroid-resistant nephrotic syndromeEnrichmentDAAM20.60
414DystoniaEnrichmentCAMK2B0.59
415Leukemia, acute myeloidEnrichmentTP530.59
416HypertelorismEnrichmentTFAP2A0.51
417ThrombocytopeniaEnrichmentSRC0.48
418Hereditary breast ovarian cancer syndromeEnrichmentTP530.47
419Body mass index quantitative trait locus 11EnrichmentSDC30.46
420Deafness, autosomal recessiveEnrichmentESRRB0.42
421Undetermined early-onset epileptic encephalopathyEnrichmentPPP3CA0.42
422Autosomal recessive nonsyndromic deafnessEnrichmentESRRB0.42
423Rare autosomal recessive non-syndromic sensorineural deafness type dfnbEnrichmentROR10.36
424Rare genetic deafnessEnrichmentESRRB0.35
425Hereditary retinal dystrophyEnrichmentFZD4, LRP50.19
426Fundus dystrophyEnrichmentFZD4, LRP50.19

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