Nectin/Necl trans heterodimerization
Pathways in the Nectin/Necl trans heterodimerization SuperPath
| # | Name | Source | Genes |
|---|---|---|---|
| 1 | Nectin/Necl trans heterodimerization | Reactome |
Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways
| # | Symbol | Description | Category | # Related Pathways |
|---|---|---|---|---|
| 1 | CADM1 | Cell Adhesion Molecule 1 | Protein Coding | 1 |
| 2 | NECTIN3 | Nectin Cell Adhesion Molecule 3 | Protein Coding | 1 |
| 3 | CADM3 | Cell Adhesion Molecule 3 | Protein Coding | 1 |
| 4 | PVR | PVR Cell Adhesion Molecule | Protein Coding | 1 |
| 5 | NECTIN1 | Nectin Cell Adhesion Molecule 1 | Protein Coding | 1 |
| 6 | NECTIN2 | Nectin Cell Adhesion Molecule 2 | Protein Coding | 1 |
| 7 | NECTIN4 | Nectin Cell Adhesion Molecule 4 | Protein Coding | 1 |
Disorders associated with Nectin/Necl trans heterodimerization SuperPath
according to GeneCards Suite gene sharing
| # | Disorder | Type | Genes | Score |
|---|---|---|---|---|
| 1 | Cleft lip/palate-ectodermal dysplasia syndrome | Enrichment | NECTIN1 | 3.29 |
| 2 | Orofacial cleft 7 | Enrichment | NECTIN1 | 3.29 |
| 3 | Charcot-marie-tooth disease, axonal, type 2ff | Enrichment | CADM3 | 3.29 |
| 4 | Ectodermal dysplasia-syndactyly syndrome 1 | Enrichment | NECTIN4 | 3.29 |
| 5 | Cleft lip and alveolus | Enrichment | NECTIN1 | 2.69 |
| 6 | Cleft upper lip | Enrichment | NECTIN1 | 2.59 |
| 7 | Cleft lip/palate | Enrichment | NECTIN1 | 2.14 |
