Nephrotic syndrome

No Pathway Network information available for Nephrotic syndrome

Pathways in the Nephrotic syndrome SuperPath

#	Name	Source	Genes
1	Nephrotic syndrome	WikiPathways	ACTN4 ALG1 ANLN APOL1 ARHGAP24 ARHGDIA CD151 CD2AP COL4A3 COL4A4 COL4A5 COQ2 COQ6 COQ8B CTLA4 CUBN CYP11B2 E2F3 EMP2 GPC5 INF2 ITGA3 ITGB4 LAMB2 LMNA LMX1B MT-TI MT-TL1 MYH9 MYO1E NPHS1 NPHS2 PAX2 PDSS2 PLCE1 PMM2 PODXL PTPRO SCARB2 SMARCAL1 SYNPO TRN-GTT4-1 TRPC6 TTC21B WDR73 WT1 YARS1 ZMPSTE24 (see all 48) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	CD151	CD151 Molecule (Raph Blood Group)	Protein Coding	1
2	SCARB2	Scavenger Receptor Class B Member 2	Protein Coding	1
3	YARS1	Tyrosyl-TRNA Synthetase 1	Protein Coding	1
4	APOL1	Apolipoprotein L1	Protein Coding	1
5	WDR73	WD Repeat Domain 73	Protein Coding	1
6	ACTN4	Actinin Alpha 4	Protein Coding	1
7	CUBN	Cubilin	Protein Coding	1
8	COQ8B	Coenzyme Q8B	Protein Coding	1
9	TTC21B	Tetratricopeptide Repeat Domain 21B	Protein Coding	1
10	NPHS2	NPHS2 Stomatin Family Member, Podocin	Protein Coding	1
11	WT1	WT1 Transcription Factor	Protein Coding	1
12	TRPC6	Transient Receptor Potential Cation Channel Subfamily C Member 6	Protein Coding	1
13	INF2	Inverted Formin 2	Protein Coding	1
14	PTPRO	Protein Tyrosine Phosphatase Receptor Type O	Protein Coding	1
15	PDSS2	Decaprenyl Diphosphate Synthase Subunit 2	Protein Coding	1
16	ALG1	ALG1 Chitobiosyldiphosphodolichol Beta-Mannosyltransferase	Protein Coding	1
17	ANLN	Anillin, Actin Binding Protein	Protein Coding	1
18	PODXL	Podocalyxin Like	Protein Coding	1
19	PMM2	Phosphomannomutase 2	Protein Coding	1
20	PLCE1	Phospholipase C Epsilon 1	Protein Coding	1
21	COQ6	Coenzyme Q6, Monooxygenase	Protein Coding	1
22	PAX2	Paired Box 2	Protein Coding	1
23	SMARCAL1	SNF2 Related Chromatin Remodeling Annealing Helicase 1	Protein Coding	1
24	NPHS1	NPHS1 Adhesion Molecule, Nephrin	Protein Coding	1
25	MYO1E	Myosin IE	Protein Coding	1
26	MYH9	Myosin Heavy Chain 9	Protein Coding	1
27	MT-TL1	Mitochondrially Encoded TRNA-Leu (UUA/G) 1	RNA Gene	1
28	MT-TI	Mitochondrially Encoded TRNA-Ile (AUU/C)	RNA Gene	1
29	LMX1B	LIM Homeobox Transcription Factor 1 Beta	Protein Coding	1
30	LMNA	Lamin A/C	Protein Coding	1
31	ARHGDIA	Rho GDP Dissociation Inhibitor Alpha	Protein Coding	1
32	LAMB2	Laminin Subunit Beta 2	Protein Coding	1
33	ITGB4	Integrin Subunit Beta 4	Protein Coding	1
34	ITGA3	Integrin Subunit Alpha 3	Protein Coding	1
35	COQ2	Coenzyme Q2, Polyprenyltransferase	Protein Coding	1
36	CD2AP	CD2 Associated Protein	Protein Coding	1
37	GPC5	Glypican 5	Protein Coding	1
38	EMP2	Epithelial Membrane Protein 2	Protein Coding	1
39	E2F3	E2F Transcription Factor 3	Protein Coding	1
40	CYP11B2	Cytochrome P450 Family 11 Subfamily B Member 2	Protein Coding	1
41	CTLA4	Cytotoxic T-Lymphocyte Associated Protein 4	Protein Coding	1
42	COL4A5	Collagen Type IV Alpha 5 Chain	Protein Coding	1
43	COL4A4	Collagen Type IV Alpha 4 Chain	Protein Coding	1
44	COL4A3	Collagen Type IV Alpha 3 Chain	Protein Coding	1
45	ZMPSTE24	Zinc Metallopeptidase STE24	Protein Coding	1
46	SYNPO	Synaptopodin	Protein Coding	1
47	ARHGAP24	Rho GTPase Activating Protein 24	Protein Coding	1
48	TRN-GTT4-1	TRNA-Asn (Anticodon GTT) 4-1	RNA Gene	1

Disorders associated with Nephrotic syndrome SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Focal segmental glomerulosclerosis	Enrichment	APOL1, COL4A4, COL4A5, COQ2, INF2, NPHS1, NPHS2, PAX2, PLCE1, PMM2, SMARCAL1, TRPC6, WT1	16.00
2	Genetic steroid-resistant nephrotic syndrome	Enrichment	ACTN4, ANLN, APOL1, ARHGAP24, ARHGDIA, CD2AP, COL4A3, COQ8B, EMP2, INF2, MYO1E, NPHS1, NPHS2, PAX2, PLCE1, PTPRO, TRPC6, WT1	16.00
3	Nephrotic syndrome	Enrichment	COL4A3, COL4A4, COL4A5, COQ2, COQ8B, INF2, ITGA3, LAMB2, LMX1B, MYO1E, NPHS1, NPHS2, PAX2, PDSS2, PLCE1, SMARCAL1, SYNPO, TRPC6, TTC21B, WDR73	11.28
4	Kidney disease	Enrichment	COL4A3, COL4A4, COL4A5, INF2, LAMB2, NPHS1, WT1	11.24
5	Nephrotic syndrome, type 1	Enrichment	ALG1, NPHS1, NPHS2, PLCE1, TTC21B	10.21
6	Digenic alport syndrome	Enrichment	COL4A3, COL4A4, COL4A5	7.38
7	Chronic kidney disease	Enrichment	COL4A4, COL4A5, CUBN, NPHS2	7.02
8	Hypertension	Enrichment	COL4A4, COL4A5, INF2, MYH9	6.61
9	Alport syndrome 3a, autosomal dominant	Enrichment	COL4A3, COL4A4, COL4A5	6.38
10	Autosomal dominant alport syndrome	Enrichment	COL4A3, COL4A4, COL4A5	6.38
11	Alport syndrome	Enrichment	COL4A3, COL4A4, COL4A5	6.38
12	Glomerulonephritis	Enrichment	APOL1, COL4A4	4.91
13	Hematuria, benign familial, 1	Enrichment	COL4A3, COL4A4	4.44
14	Restrictive dermopathy 1	Enrichment	LMNA, ZMPSTE24	4.44
15	Restrictive dermopathy	Enrichment	LMNA, ZMPSTE24	4.44
16	Hutchinson-gilford progeria syndrome	Enrichment	LMNA, ZMPSTE24	4.14
17	Alport syndrome 2, autosomal recessive	Enrichment	COL4A3, COL4A4	4.14
18	Autosomal recessive alport syndrome	Enrichment	COL4A3, COL4A4	4.14
19	Developmental and epileptic encephalopathy 36	Enrichment	ALG1, PMM2	3.74
20	Myoclonic epilepsy associated with ragged-red fibers	Enrichment	MT-TI, MT-TL1	3.10
21	Atypical hemolytic-uremic syndrome	Enrichment	COL4A5, SMARCAL1	2.90
22	Congenital disorder of glycosylation, type in	Enrichment	ALG1, PMM2	2.79
23	Cardiomyopathy, familial hypertrophic, 1	Enrichment	LMNA, MT-TI	2.49
24	Muscular dystrophy	Enrichment	LMNA, PMM2	2.49
25	Focal segmental glomerulosclerosis 10	Enrichment	LMX1B	2.45
26	Alport syndrome 1, x-linked	Enrichment	COL4A5	2.45
27	Focal segmental glomerulosclerosis 1	Enrichment	ACTN4	2.45
28	Charcot-marie-tooth disease, axonal, mitochondrial	Enrichment	MT-TL1	2.45
29	Cyclic vomiting syndrome	Enrichment	MT-TL1	2.45
30	Deafness, autosomal dominant 17	Enrichment	MYH9	2.45
31	Celiac disease 3	Enrichment	CTLA4	2.45
32	Raph blood group system	Enrichment	CD151	2.45
33	Focal segmental glomerulosclerosis 4	Enrichment	APOL1	2.45
34	Nail-patella syndrome	Enrichment	LMX1B	2.45
35	Charcot-marie-tooth disease, dominant intermediate c	Enrichment	YARS1	2.45
36	Focal segmental glomerulosclerosis 2	Enrichment	TRPC6	2.45
37	Charcot-marie-tooth disease, dominant intermediate e	Enrichment	INF2	2.45
38	Schimke immunoosseous dysplasia	Enrichment	SMARCAL1	2.45
39	Nephrotic syndrome, type 10	Enrichment	EMP2	2.45
40	Focal segmental glomerulosclerosis 8	Enrichment	ANLN	2.45
41	Nephrotic syndrome, type 8	Enrichment	ARHGDIA	2.45
42	Congenital disorder of glycosylation, type ia	Enrichment	PMM2	2.45
43	Hypomagnesemia, hypertension, and hypercholesterolemia, mitochondrial	Enrichment	MT-TI	2.45
44	Type 1 diabetes mellitus 12	Enrichment	CTLA4	2.45
45	Nephrotic syndrome, type 9	Enrichment	COQ8B	2.45
46	Meacham syndrome	Enrichment	WT1	2.45
47	Epidermolysis bullosa simplex 7, with nephropathy and deafness	Enrichment	CD151	2.45
48	Focal segmental glomerulosclerosis 3	Enrichment	CD2AP	2.45
49	Nephrotic syndrome, type 6	Enrichment	PTPRO	2.45
50	Focal segmental glomerulosclerosis 5	Enrichment	INF2	2.45
51	Focal segmental glomerulosclerosis 6	Enrichment	MYO1E	2.45
52	Coenzyme q10 deficiency, primary, 3	Enrichment	PDSS2	2.45
53	Atypical werner syndrome	Enrichment	LMNA	2.45
54	Mitochondrial dna-related mitochondrial myopathy	Enrichment	MT-TL1	2.45
55	Lipoid nephrosis	Enrichment	LMX1B	2.45
56	Hypertrophic cardiomyopathy and renal tubular disease due to mitochondrial dna mutation	Enrichment	MT-TL1	2.45
57	Glucose intolerance	Enrichment	MT-TL1	2.45
58	Mandibuloacral dysplasia	Enrichment	LMNA	2.45
59	Atrioventricular block	Enrichment	LMNA	2.45
60	Autosomal dominant nonsyndromic hearing loss 17	Enrichment	MYH9	2.45
61	X-linked alport syndrome	Enrichment	COL4A5	2.45
62	Familial nephrotic syndrome	Enrichment	NPHS1	2.45
63	Lmna-related cardiocutaneous progeria syndrome	Enrichment	LMNA	2.45
64	Pax2-related disorder	Enrichment	PAX2	2.45
65	Autosomal semi-dominant severe lipodystrophic laminopathy	Enrichment	LMNA	2.45
66	Multiple system atrophy, parkinsonian type	Enrichment	COQ2	2.45
67	Autosomal recessive axonal hereditary motor and sensory neuropathy	Enrichment	LMNA	2.45
68	Laminopathy	Enrichment	LMNA	2.45
69	Papillorenal syndrome	Enrichment	PAX2	2.15
70	Hashimoto thyroiditis	Enrichment	CTLA4	2.15
71	Multiple system atrophy 1	Enrichment	COQ2	2.15
72	Corticosterone methyloxidase type i deficiency	Enrichment	CYP11B2	2.15
73	Mandibuloacral dysplasia with type a lipodystrophy	Enrichment	LMNA	2.15
74	Denys-drash syndrome	Enrichment	WT1	2.15
75	Myasthenic syndrome, congenital, 5	Enrichment	LAMB2	2.15
76	Nephrotic syndrome, type 2	Enrichment	NPHS2	2.15
77	Cataract 35	Enrichment	MYH9	2.15
78	Nephrotic syndrome, type 4	Enrichment	WT1	2.15
79	Corticosterone methyloxidase type ii deficiency	Enrichment	CYP11B2	2.15
80	Heart-hand syndrome, slovenian type	Enrichment	LMNA	2.15
81	Charcot-marie-tooth disease, axonal, type 2b1	Enrichment	LMNA	2.15
82	Coenzyme q10 deficiency, primary, 6	Enrichment	COQ6	2.15
83	Frasier syndrome	Enrichment	WT1	2.15
84	Cardiomyopathy, dilated, with hypergonadotropic hypogonadism	Enrichment	LMNA	2.15
85	Specific language impairment 5	Enrichment	COL4A4	2.15
86	Pierson syndrome	Enrichment	LAMB2	2.15
87	Nephronophthisis 12	Enrichment	TTC21B	2.15
88	Short-rib thoracic dysplasia 4 with or without polydactyly	Enrichment	TTC21B	2.15
89	Cardiomyopathy, dilated, 1d	Enrichment	LMNA	2.15
90	Restrictive dermopathy 2	Enrichment	LMNA	2.15
91	Emery-dreifuss muscular dystrophy 3, autosomal recessive	Enrichment	LMNA	2.15
92	Epidermolysis bullosa, junctional 5a, intermediate	Enrichment	ITGB4	2.15
93	Nephrotic syndrome, type 5, with or without ocular abnormalities	Enrichment	LAMB2	2.15
94	Epidermolysis bullosa, junctional 7, with interstitial lung disease and nephrotic syndrome	Enrichment	ITGA3	2.15
95	Focal segmental glomerulosclerosis 7	Enrichment	PAX2	2.15
96	Mandibuloacral dysplasia with type b lipodystrophy	Enrichment	ZMPSTE24	2.15
97	Lipodystrophy, familial partial, type 1	Enrichment	LMNA	2.15
98	Pseudosarcomatous fibromatosis	Enrichment	MYH9	2.15
99	9q33.3q34.11 microdeletion syndrome	Enrichment	LMX1B	2.15
100	Gitelman-like kidney tubulopathy due to mitochondrial dna mutation	Enrichment	MT-TI	2.15
101	Localized junctional epidermolysis bullosa, non-herlitz type	Enrichment	ITGB4	2.15
102	Familial partial lipodystrophy	Enrichment	LMNA	2.15
103	Familial hypoaldosteronism	Enrichment	CYP11B2	2.15
104	Renal hypoplasia, bilateral	Enrichment	PAX2	2.15
105	Genetic nephrotic syndrome	Enrichment	NPHS2	2.15
106	Charcot-marie-tooth disease type 2b1	Enrichment	LMNA	2.15
107	Idiopathic nephrotic syndrome	Enrichment	NPHS2	2.15
108	Multiple system atrophy	Enrichment	COQ2	2.15
109	Desmoplastic small round cell tumor	Enrichment	WT1	2.15
110	X-linked diffuse leiomyomatosis-alport syndrome	Enrichment	COL4A5	2.15
111	Early-onset familial hypoaldosteronism	Enrichment	CYP11B2	2.15
112	Multiple system atrophy, cerebellar type	Enrichment	COQ2	2.15
113	Leber hereditary optic neuropathy, modifier of	Enrichment	MT-TI, MT-TL1	2.12
114	Mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes	Enrichment	MT-TI, MT-TL1	2.10
115	Cerebral palsy	Enrichment	MT-TL1, PMM2	2.08
116	Macular degeneration, age-related, 2	Enrichment	MT-TL1	1.98
117	Macrothrombocytopenia and granulocyte inclusions with or without nephritis or sensorineural hearing loss	Enrichment	MYH9	1.98
118	Mesothelioma, malignant	Enrichment	WT1	1.98
119	Visceral steatosis, congenital	Enrichment	YARS1	1.98
120	3-methylglutaconic aciduria, type i	Enrichment	MT-TL1	1.98
121	Mycosis fungoides	Enrichment	CTLA4	1.98
122	Nephronophthisis 2	Enrichment	TTC21B	1.98
123	Nephrotic syndrome, type 3	Enrichment	PLCE1	1.98
124	Coenzyme q10 deficiency, primary, 1	Enrichment	COQ2	1.98
125	Lipodystrophy, familial partial, type 2	Enrichment	LMNA	1.98
126	Immune dysregulation with autoimmunity, immunodeficiency, and lymphoproliferation	Enrichment	CTLA4	1.98
127	Muscular dystrophy, congenital, lmna-related	Enrichment	LMNA	1.98
128	Nephrotic syndrome, type 24	Enrichment	NPHS2	1.98
129	Pilarowski-bjornsson syndrome	Enrichment	COL4A3	1.98
130	Neurologic, endocrine, and pancreatic disease, multisystem, infantile-onset 2	Enrichment	YARS1	1.98
131	Alport syndrome 3b, autosomal recessive	Enrichment	COL4A3	1.98
132	Proteinuria, chronic benign	Enrichment	CUBN	1.98
133	Chronic progressive external ophthalmoplegia	Enrichment	MT-TI	1.98
134	Asparagine synthetase deficiency	Enrichment	CTLA4	1.98
135	Hematuria, benign familial, 2	Enrichment	COL4A3	1.98
136	Atypical juvenile parkinsonism	Enrichment	PODXL	1.98
137	Congenital microcephaly - severe encephalopathy - progressive cerebral atrophy syndrome	Enrichment	CTLA4	1.98
138	Adult-onset myasthenia gravis	Enrichment	CTLA4	1.98
139	Age related macular degeneration	Enrichment	MT-TL1	1.98
140	Steatotic liver disease	Enrichment	YARS1	1.98
141	Saczary syndrome	Enrichment	CTLA4	1.98
142	Aniridia 1	Enrichment	WT1	1.85
143	Gaucher disease, type i	Enrichment	SCARB2	1.85
144	Emery-dreifuss muscular dystrophy 1, x-linked	Enrichment	LMNA	1.85
145	Epilepsy, progressive myoclonic, 4, with or without renal failure	Enrichment	SCARB2	1.85
146	Microtia-anotia	Enrichment	LMNA	1.85
147	Congenital disorder of glycosylation, type ik	Enrichment	ALG1	1.85
148	Diabetes and deafness, maternally inherited	Enrichment	MT-TL1	1.85
149	Epidermolysis bullosa simplex 5c, with pyloric atresia	Enrichment	ITGB4	1.85
150	Developmental and epileptic encephalopathy 4	Enrichment	LMX1B	1.85
151	Immunodeficiency, common variable, 1	Enrichment	CTLA4	1.85
152	Emery-dreifuss muscular dystrophy	Enrichment	LMNA	1.85
153	Cerebrovascular disease	Enrichment	MT-TL1	1.85
154	Neurologic, endocrine, and pancreatic disease, multisystem, infantile-onset 1	Enrichment	YARS1	1.85
155	Sick sinus syndrome	Enrichment	LMNA	1.85
156	Full schwannomatosis	Enrichment	COQ6	1.85
157	Mitochondrial dna-related progressive external ophthalmoplegia	Enrichment	MT-TL1	1.85
158	Epidermolysis bullosa simplex 1c, localized	Enrichment	ITGB4	1.76
159	Galloway-mowat syndrome 1	Enrichment	WDR73	1.76
160	Kearns-sayre syndrome	Enrichment	MT-TL1	1.76
161	Parkinson disease 2, autosomal recessive juvenile	Enrichment	PODXL	1.76
162	Atrioventricular septal defect	Enrichment	SMARCAL1	1.76
163	Deafness, autosomal recessive 63	Enrichment	MYH9	1.76
164	Leber congenital amaurosis 10	Enrichment	WT1	1.76
165	Autosomal recessive limb-girdle muscular dystrophy type 2b	Enrichment	LMNA	1.76
166	Histiocytoid hemangioma	Enrichment	LMNA	1.76
167	Parkin type of early-onset parkinson disease	Enrichment	PODXL	1.76
168	Aplasia cutis congenita	Enrichment	ITGB4	1.76
169	Primary ovarian insufficiency	Enrichment	PMM2, WT1	1.73
170	Hyperaldosteronism, familial, type i	Enrichment	CYP11B2	1.68
171	Emery-dreifuss muscular dystrophy 2, autosomal dominant	Enrichment	LMNA	1.68
172	Epidermolysis bullosa, junctional 1a, intermediate	Enrichment	ITGB4	1.68
173	Wilms tumor, aniridia, genitourinary anomalies, and impaired intellectual development syndrome	Enrichment	WT1	1.68
174	Epidermolysis bullosa, junctional 5b, with pyloric atresia	Enrichment	ITGB4	1.68
175	Wilms tumor 5	Enrichment	WT1	1.68
176	Hemangioma, capillary infantile	Enrichment	MYH9	1.68
177	Deafness, nonsyndromic sensorineural, mitochondrial	Enrichment	MT-TI	1.68
178	Congenital anomalies of kidney and urinary tract 1	Enrichment	PAX2	1.68
179	Granulomatosis with polyangiitis	Enrichment	CTLA4	1.68
180	Junctional epidermolysis bullosa non-herlitz type	Enrichment	ITGB4	1.68
181	Renal hypoplasia	Enrichment	PAX2	1.68
182	Megaloblastic anemia	Enrichment	CUBN	1.68
183	Bethlem myopathy 1a	Enrichment	LMNA	1.61
184	Imerslund-grasbeck syndrome 1	Enrichment	CUBN	1.61
185	Retinal degeneration	Enrichment	YARS1	1.61
186	Epidermolysis bullosa simplex	Enrichment	ITGB4	1.61
187	Leigh syndrome, nuclear	Enrichment	MT-TI, MT-TL1	1.61
188	Short-rib thoracic dysplasia 12	Enrichment	TTC21B	1.55
189	Congenital muscular dystrophy	Enrichment	LMNA	1.55
190	Myocarditis	Enrichment	LMNA	1.55
191	Difference of sex development	Enrichment	WT1	1.55
192	Infantile nephronophthisis	Enrichment	TTC21B	1.55
193	Leigh disease	Enrichment	MT-TI, MT-TL1	1.53
194	Arrhythmogenic right ventricular dysplasia, familial, 9	Enrichment	LMNA	1.50
195	Leukemia, acute lymphoblastic 3	Enrichment	WT1	1.50
196	Cystic kidney disease	Enrichment	PAX2	1.50
197	Junctional epidermolysis bullosa	Enrichment	ITGB4	1.50
198	Rare genetic deafness	Enrichment	COL4A5, MYH9	1.50
199	Dilated cardiomyopathy	Enrichment	LMNA, MT-TI	1.49
200	Galloway-mowat syndrome	Enrichment	WDR73	1.46
201	Mitochondrial encephalomyopathy	Enrichment	MT-TL1	1.46
202	Progressive myoclonus epilepsy	Enrichment	SCARB2	1.46
203	Rare mitochondrial non-syndromic sensorineural deafness	Enrichment	MT-TI	1.46
204	Mitochondrial disease	Enrichment	MT-TI, MT-TL1	1.42
205	Leigh syndrome, mitochondrial	Enrichment	MT-TL1	1.42
206	Myelodysplastic syndrome	Enrichment	MT-TL1	1.42
207	46,xy complete gonadal dysgenesis	Enrichment	WT1	1.42
208	Diabetes mellitus	Enrichment	PMM2	1.42
209	Cardiac conduction defect	Enrichment	LMNA	1.38
210	Muscular dystrophy, limb-girdle, autosomal recessive 2	Enrichment	LMNA	1.38
211	Short-rib thoracic dysplasia 6 with or without polydactyly	Enrichment	TTC21B	1.38
212	Early-onset parkinson's disease	Enrichment	PODXL	1.38
213	Inherited isolated arrhythmogenic ventricular dysplasia, biventricular variant	Enrichment	LMNA	1.38
214	Inherited isolated arrhythmogenic cardiomyopathy, dominant-left variant	Enrichment	LMNA	1.38
215	Leber plus disease	Enrichment	MT-TI, MT-TL1	1.35
216	Microphthalmia/coloboma 12	Enrichment	PAX2	1.35
217	Senior-loken syndrome 1	Enrichment	TTC21B	1.35
218	Multiple sclerosis	Enrichment	ITGB4	1.31
219	Myoclonic epilepsy of unverricht and lundborg	Enrichment	SCARB2	1.31
220	Inherited isolated arrhythmogenic cardiomyopathy, dominant-right variant	Enrichment	LMNA	1.31
221	46,xy partial gonadal dysgenesis	Enrichment	WT1	1.31
222	Isolated macular dystrophy	Enrichment	COL4A5	1.31
223	Coloboma of macula	Enrichment	PAX2	1.29
224	Wilms tumor 1	Enrichment	WT1	1.29
225	Myopia	Enrichment	COL4A4	1.29
226	Cerebellar hypoplasia/atrophy, epilepsy, and global developmental delay	Enrichment	PMM2	1.26
227	Arrhythmogenic right ventricular cardiomyopathy	Enrichment	LMNA	1.26
228	Isolated congenital microcephaly	Enrichment	SMARCAL1	1.26
229	Sudden infant death syndrome	Enrichment	MT-TL1	1.23
230	Cardiomyopathy, dilated, 1e	Enrichment	LMNA	1.23
231	Neuromuscular disease	Enrichment	LMNA	1.21
232	Polycystic kidney disease	Enrichment	COL4A4	1.21
233	Neuropathy, hereditary motor and sensory, okinawa type	Enrichment	LMNA	1.19
234	Cardiomyopathy, dilated, 1a	Enrichment	LMNA	1.14
235	Mitochondrial complex iv deficiency, nuclear type 1	Enrichment	MT-TL1	1.12
236	Skin disease	Enrichment	ITGB4	1.12
237	Jeune thoracic dystrophy	Enrichment	TTC21B	1.07
238	Mitochondrial complex v deficiency, mitochondrial type 1	Enrichment	MT-TI	1.05
239	Neuropathy, ataxia, and retinitis pigmentosa	Enrichment	MT-TI	1.05
240	Striatonigral degeneration, infantile, mitochondrial	Enrichment	MT-TI	1.05
241	Brugada syndrome	Enrichment	LMNA	1.05
242	Auditory neuropathy	Enrichment	MT-TL1	1.05
243	Camptodactyly of fingers	Enrichment	MT-TI	1.05
244	Asphyxiating thoracic dystrophy	Enrichment	TTC21B	1.02
245	Long qt syndrome	Enrichment	LMNA	0.98
246	Connective tissue disease	Enrichment	TTC21B	0.97
247	Peripheral nervous system disease	Enrichment	LMNA	0.97
248	Neuropathy	Enrichment	LMNA	0.97
249	Short-rib thoracic dysplasia 1 with or without polydactyly	Enrichment	TTC21B	0.96
250	Familial hypertrophic cardiomyopathy	Enrichment	MT-TI	0.96
251	Nephronophthisis	Enrichment	TTC21B	0.96
252	Cakut	Enrichment	PAX2	0.94
253	Left ventricular noncompaction	Enrichment	LMNA	0.93
254	Dystonia	Enrichment	WDR73	0.93
255	Systemic lupus erythematosus	Enrichment	CTLA4	0.89
256	Epilepsy	Enrichment	TTC21B	0.88
257	Charcot-marie-tooth disease	Enrichment	LMNA	0.87
258	Benign epilepsy with centrotemporal spikes	Enrichment	SCARB2	0.87
259	Centralopathic epilepsy	Enrichment	SCARB2	0.85
260	Sensorineural hearing loss	Enrichment	MT-TL1	0.80
261	Thrombocytopenia	Enrichment	MYH9	0.80
262	Body mass index quantitative trait locus 11	Enrichment	MYH9	0.79
263	Hypertelorism	Enrichment	MT-TI	0.77
264	Rare autosomal dominant non-syndromic sensorineural deafness type dfna	Enrichment	MYH9	0.77
265	Familial isolated dilated cardiomyopathy	Enrichment	LMNA	0.77
266	Retinitis pigmentosa	Enrichment	COQ8B, MT-TI	0.76
267	Deafness, autosomal recessive	Enrichment	MYH9	0.70
268	Autosomal recessive nonsyndromic deafness	Enrichment	MYH9	0.69
269	Rare autosomal recessive non-syndromic sensorineural deafness type dfnb	Enrichment	MYH9	0.57
270	Hereditary retinal dystrophy	Enrichment	PAX2, TTC21B	0.56
271	Fundus dystrophy	Enrichment	PAX2, TTC21B	0.56
272	Ovarian cancer	Enrichment	WT1	0.52
273	Congenital nervous system abnormality	Enrichment	WDR73	0.50
274	Nervous system disease	Enrichment	WDR73	0.50
275	Autism spectrum disorder	Enrichment	CUBN	0.49
276	Microcephaly	Enrichment	SMARCAL1	0.45
277	Inherited cancer-predisposing syndrome	Enrichment	WT1	0.43

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Nephrotic syndrome

Pathway Network for Nephrotic syndrome

Member Pathways for Nephrotic syndrome

Pathways in the Nephrotic syndrome SuperPath

Associated Genes for Nephrotic syndrome

Associated Disorders for Nephrotic syndrome

Disorders associated with Nephrotic syndrome SuperPath

STRING Interaction Network for Nephrotic syndrome

Sources for Nephrotic syndrome