Netrin-UNC5B signaling pathway

No Pathway Network information available for Netrin-UNC5B signaling pathway

Pathways in the Netrin-UNC5B signaling pathway SuperPath

#	Name	Source	Genes
1	Netrin-UNC5B signaling pathway	WikiPathways	AGAP2 AKT1 ALPL ARHGEF12 CASP3 CCL2 CCN2 CDH5 CIP2A COL1A1 DAPK1 DCSTAMP FYN ICAM1 IL10 IL1A INPP5D ITGB4 JUN KDR MAP2K1 MAP2K2 MAPK1 MAPK14 MAPK3 MYF5 NEO1 NTN1 NTN3 NTN4 PIK3CA PLEKHH1 PPP1CA PPP2R1B PRKCA PTK2 PTK2B PTPA PTPN11 RAC1 RAF1 RGMA RHOA RLF ROBO4 SELE SRC TNF TP53 UNC5B VCAM1 YAP1 (see all 52) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	RGMA	Repulsive Guidance Molecule BMP Co-Receptor A	Protein Coding	1
2	NTN1	Netrin 1	Protein Coding	1
3	CASP3	Caspase 3	Protein Coding	1
4	DCSTAMP	Dendrocyte Expressed Seven Transmembrane Protein	Protein Coding	1
5	VCAM1	Vascular Cell Adhesion Molecule 1	Protein Coding	1
6	TP53	Tumor Protein P53	Protein Coding	1
7	TNF	Tumor Necrosis Factor	Protein Coding	1
8	SRC	SRC Proto-Oncogene, Non-Receptor Tyrosine Kinase	Protein Coding	1
9	SELE	Selectin E	Protein Coding	1
10	CCL2	C-C Motif Chemokine Ligand 2	Protein Coding	1
11	RAF1	Raf-1 Proto-Oncogene, Serine/Threonine Kinase	Protein Coding	1
12	RAC1	Rac Family Small GTPase 1	Protein Coding	1
13	PTPN11	Protein Tyrosine Phosphatase Non-Receptor Type 11	Protein Coding	1
14	PLEKHH1	Pleckstrin Homology, MyTH4 And FERM Domain Containing H1	Protein Coding	1
15	PTK2	Protein Tyrosine Kinase 2	Protein Coding	1
16	MAP2K2	Mitogen-Activated Protein Kinase Kinase 2	Protein Coding	1
17	MAP2K1	Mitogen-Activated Protein Kinase Kinase 1	Protein Coding	1
18	MAPK3	Mitogen-Activated Protein Kinase 3	Protein Coding	1
19	MAPK1	Mitogen-Activated Protein Kinase 1	Protein Coding	1
20	PRKCA	Protein Kinase C Alpha	Protein Coding	1
21	PTPA	Protein Phosphatase 2 Phosphatase Activator	Protein Coding	1
22	PPP2R1B	Protein Phosphatase 2 Scaffold Subunit Abeta	Protein Coding	1
23	ROBO4	Roundabout Guidance Receptor 4	Protein Coding	1
24	PIK3CA	Phosphatidylinositol-4,5-Bisphosphate 3-Kinase Catalytic Subunit Alpha	Protein Coding	1
25	RHOA	Ras Homolog Family Member A	Protein Coding	1
26	KDR	Kinase Insert Domain Receptor	Protein Coding	1
27	JUN	Jun Proto-Oncogene, AP-1 Transcription Factor Subunit	Protein Coding	1
28	ITGB4	Integrin Subunit Beta 4	Protein Coding	1
29	INPP5D	Inositol Polyphosphate-5-Phosphatase D	Protein Coding	1
30	IL10	Interleukin 10	Protein Coding	1
31	IL1A	Interleukin 1 Alpha	Protein Coding	1
32	ICAM1	Intercellular Adhesion Molecule 1	Protein Coding	1
33	FYN	FYN Proto-Oncogene, Src Family Tyrosine Kinase	Protein Coding	1
34	ALPL	Alkaline Phosphatase, Biomineralization Associated	Protein Coding	1
35	ARHGEF12	Rho Guanine Nucleotide Exchange Factor 12	Protein Coding	1
36	UNC5B	Unc-5 Netrin Receptor B	Protein Coding	1
37	PTK2B	Protein Tyrosine Kinase 2 Beta	Protein Coding	1
38	AKT1	AKT Serine/Threonine Kinase 1	Protein Coding	1
39	DAPK1	Death Associated Protein Kinase 1	Protein Coding	1
40	CCN2	Cellular Communication Network Factor 2	Protein Coding	1
41	MAPK14	Mitogen-Activated Protein Kinase 14	Protein Coding	1
42	COL1A1	Collagen Type I Alpha 1 Chain	Protein Coding	1
43	YAP1	Yes1 Associated Transcriptional Regulator	Protein Coding	1
44	CDH5	Cadherin 5	Protein Coding	1
45	AGAP2	ArfGAP With GTPase Domain, Ankyrin Repeat And PH Domain 2	Protein Coding	1
46	RLF	RLF Zinc Finger	Protein Coding	1
47	NTN4	Netrin 4	Protein Coding	1
48	CIP2A	Cellular Inhibitor Of PP2A	Protein Coding	1
49	PPP1CA	Protein Phosphatase 1 Catalytic Subunit Alpha	Protein Coding	1
50	NTN3	Netrin 3	Protein Coding	1
51	NEO1	Neogenin 1	Protein Coding	1
52	MYF5	Myogenic Factor 5	Protein Coding	1

Disorders associated with Netrin-UNC5B signaling pathway SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Noonan syndrome and noonan-related syndrome	Enrichment	MAP2K1, MAP2K2, PTPN11, RAF1	6.60
2	Breast adenocarcinoma	Enrichment	AKT1, PIK3CA, TP53	5.98
3	Noonan syndrome 1	Enrichment	MAP2K1, MAP2K2, PTPN11, RAF1	5.79
4	Rasopathy	Enrichment	MAP2K1, MAP2K2, PTPN11, RAF1	5.57
5	Cardiofaciocutaneous syndrome 1	Enrichment	MAP2K1, MAP2K2	4.07
6	Cardiofaciocutaneous syndrome	Enrichment	MAP2K1, MAP2K2	4.07
7	Noonan syndrome with multiple lentigines	Enrichment	PTPN11, RAF1	4.07
8	Cerebral malaria	Enrichment	ICAM1, TNF	4.07
9	Lymphoma	Enrichment	PTPN11, TP53	3.84
10	Breast cancer	Enrichment	AKT1, JUN, PIK3CA, TP53	3.72
11	Hemihyperplasia, isolated	Enrichment	PIK3CA, RHOA	3.67
12	Capillary malformation-arteriovenous malformation 1	Enrichment	MAP2K1, PIK3CA	3.52
13	Noonan syndrome 3	Enrichment	PTPN11, RAF1	3.52
14	Gallbladder cancer	Enrichment	PIK3CA, TP53	3.52
15	Colorectal cancer	Enrichment	AKT1, PIK3CA, SRC, TP53	3.47
16	Arteriovenous malformation	Enrichment	MAP2K1, PIK3CA	3.29
17	Adult hepatocellular carcinoma	Enrichment	PIK3CA, TP53	3.29
18	Cowden syndrome	Enrichment	AKT1, PIK3CA	3.29
19	Hereditary breast carcinoma	Enrichment	AKT1, PIK3CA, TP53	3.20
20	Myopathy, x-linked, with excessive autophagy	Enrichment	MAP2K1, PIK3CA	3.20
21	Lung non-small cell carcinoma	Enrichment	MAP2K1, PIK3CA	3.11
22	Specific learning disability	Enrichment	MAPK1, PTPN11	3.11
23	Meningioma	Enrichment	AKT1, PIK3CA	3.03
24	Lip and oral cavity carcinoma	Enrichment	PIK3CA, TP53	3.03
25	Osteoporosis	Enrichment	COL1A1, SRC	2.89
26	Human immunodeficiency virus type 1	Enrichment	CCL2, IL10	2.67
27	Hepatocellular carcinoma	Enrichment	PIK3CA, TP53	2.50
28	Brittle bone disorder	Enrichment	ALPL, COL1A1	2.46
29	Malaria	Enrichment	ICAM1, TNF	2.46
30	Scoliosis	Enrichment	MYF5, PTPN11	2.42
31	Macrodactyly	Enrichment	PIK3CA	2.42
32	Proteus syndrome	Enrichment	AKT1	2.42
33	Metachondromatosis	Enrichment	PTPN11	2.42
34	Noonan syndrome 5	Enrichment	RAF1	2.42
35	Hypophosphatasia, adult	Enrichment	ALPL	2.42
36	Melorheostosis, isolated	Enrichment	MAP2K1	2.42
37	Megalencephaly, autosomal dominant	Enrichment	PIK3CA	2.42
38	Coloboma, ocular, with or without hearing impairment, cleft lip/palate, and/or impaired intellectual development	Enrichment	YAP1	2.42
39	Leopard syndrome 1	Enrichment	PTPN11	2.42
40	Cardiomyopathy, dilated, 1nn	Enrichment	RAF1	2.42
41	Cowden syndrome 5	Enrichment	PIK3CA	2.42
42	Cardiofaciocutaneous syndrome 3	Enrichment	MAP2K1	2.42
43	Hypophosphatasia, childhood	Enrichment	ALPL	2.42
44	Cerebral cavernous malformations 4	Enrichment	PIK3CA	2.42
45	Noonan syndrome 13	Enrichment	MAPK1	2.42
46	Parkinson disease 25, autosomal recessive early-onset, with impaired intellectual development	Enrichment	PTPA	2.42
47	Bone marrow failure syndrome 5	Enrichment	TP53	2.42
48	Graft-versus-host disease	Enrichment	IL10	2.42
49	Papilloma of choroid plexus	Enrichment	TP53	2.42
50	Mirror movements 4	Enrichment	NTN1	2.42
51	Basal cell carcinoma 7	Enrichment	TP53	2.42
52	Aortic valve disease 3	Enrichment	ROBO4	2.42
53	Anaplastic thyroid carcinoma	Enrichment	TP53	2.42
54	Uveal coloboma-cleft lip and palate-intellectual disability	Enrichment	YAP1	2.42
55	Hemifacial myohyperplasia	Enrichment	PIK3CA	2.42
56	Capillary malformation of the lower lip, lymphatic malformation of face and neck, asymmetry of face and limbs, and partial/generalized overgrowth	Enrichment	PIK3CA	2.42
57	Ophthalmoplegia, external, with rib and vertebral anomalies	Enrichment	MYF5	2.42
58	Melorheostosis	Enrichment	MAP2K1	2.42
59	Leopard syndrome 2	Enrichment	RAF1	2.42
60	Cardiofaciocutaneous syndrome 4	Enrichment	MAP2K2	2.42
61	Cowden syndrome 6	Enrichment	AKT1	2.42
62	Ductal carcinoma in situ	Enrichment	TP53	2.42
63	Thrombocytopenia 6	Enrichment	SRC	2.42
64	Ectodermal dysplasia with facial dysmorphism and acral, ocular, and brain anomalies	Enrichment	RHOA	2.42
65	Prenatal benign hypophosphatasia	Enrichment	ALPL	2.42
66	Linear hypopigmentation and craniofacial asymmetry with acral, ocular and brain anomalies	Enrichment	RHOA	2.42
67	Trigonitis	Enrichment	RAF1	2.42
68	Segmental progressive overgrowth syndrome with fibroadipose hyperplasia	Enrichment	PIK3CA	2.42
69	Thyroid gland undifferentiated carcinoma	Enrichment	TP53	2.42
70	Tufted angioma of skin	Enrichment	KDR	2.42
71	Asphyxia neonatorum	Enrichment	COL1A1	2.42
72	Small-cell carcinoma of the ovary of hypercalcemic type	Enrichment	TP53	2.42
73	Hypospadias	Enrichment	PIK3CA	2.42
74	Diffuse pediatric-type high-grade glioma, h3-wildtype and idh-wildtype	Enrichment	TP53	2.42
75	Choroid plexus cancer	Enrichment	TP53	2.42
76	Rare venous malformation	Enrichment	PIK3CA	2.42
77	Diaphragmatic eventration	Enrichment	PIK3CA	2.42
78	Pik3ca-related overgrowth spectrum	Enrichment	PIK3CA	2.42
79	Pleomorphic xanthoastrocytoma	Enrichment	TP53	2.42
80	Rare combined vascular malformation	Enrichment	PIK3CA	2.42
81	Cavernous lymphangioma	Enrichment	PIK3CA	2.42
82	Pik3ca-related overgrowth syndrome	Enrichment	PIK3CA	2.42
83	Microcephaly-corpus callosum and cerebellar vermis hypoplasia-facial dysmorphism-intellectual disability syndrom	Enrichment	RAC1	2.42
84	Hemihyperplasia-multiple lipomatosis syndrome	Enrichment	PIK3CA	2.42
85	Eccrine angiomatous hamartoma	Enrichment	PIK3CA	2.42
86	Macrodactyly of toe	Enrichment	PIK3CA	2.42
87	Malignant astrocytoma	Enrichment	PTPN11	2.42
88	Bladder cancer	Enrichment	PIK3CA, TP53	2.26
89	Prostate cancer	Enrichment	PIK3CA, TP53	2.26
90	Lung cancer	Enrichment	PIK3CA, PPP2R1B	2.18
91	Ovarian cancer	Enrichment	AKT1, PIK3CA, TP53	2.17
92	Epiphyseal dysplasia, multiple, 1	Enrichment	COL1A1	2.12
93	Adrenocortical carcinoma, hereditary	Enrichment	TP53	2.12
94	Kyphomelic dysplasia	Enrichment	CCN2	2.12
95	Dermatofibrosarcoma protuberans	Enrichment	COL1A1	2.12
96	Cervical cancer	Enrichment	TP53	2.12
97	Keratosis, seborrheic	Enrichment	PIK3CA	2.12
98	Angioma, tufted	Enrichment	KDR	2.12
99	Noonan syndrome 8	Enrichment	PIK3CA	2.12
100	Lymphoma, hodgkin, classic	Enrichment	TP53	2.12
101	Spondyloepimetaphyseal dysplasia, li-shao-li type	Enrichment	CCN2	2.12
102	Combined osteogenesis imperfecta and ehlers-danlos syndrome 1	Enrichment	COL1A1	2.12
103	Intellectual developmental disorder, autosomal dominant 48	Enrichment	RAC1	2.12
104	Alpha-thalassemia/impaired intellectual development syndrome, x-linked	Enrichment	ALPL	2.12
105	Epidermolysis bullosa, junctional 5a, intermediate	Enrichment	ITGB4	2.12
106	Werner syndrome	Enrichment	PTPN11	2.12
107	Ehlers-danlos syndrome, arthrochalasia type, 2	Enrichment	COL1A1	2.12
108	Immunodeficiency 127	Enrichment	TNF	2.12
109	Rosette-forming glioneuronal tumor	Enrichment	PIK3CA	2.12
110	Congenital fibrosarcoma	Enrichment	TP53	2.12
111	Stickler syndrome, type ii	Enrichment	COL1A1	2.12
112	Li-fraumeni syndrome 1	Enrichment	TP53	2.12
113	Sarcoma	Enrichment	TP53	2.12
114	Hypophosphatasia	Enrichment	ALPL	2.12
115	Cervix carcinoma	Enrichment	TP53	2.12
116	Hodgkin's lymphoma	Enrichment	TP53	2.12
117	Alpha thalassemia-x-linked intellectual disability syndrome	Enrichment	ALPL	2.12
118	Ehlers-danlos/osteogenesis imperfecta syndrome	Enrichment	COL1A1	2.12
119	Localized junctional epidermolysis bullosa, non-herlitz type	Enrichment	ITGB4	2.12
120	Pleomorphic rhabdomyosarcoma	Enrichment	TP53	2.12
121	Tafro syndrome	Enrichment	MAP2K2	2.12
122	Systemic lupus erythematosus	Enrichment	IL10, TNF	2.01
123	Hypophosphatasia, infantile	Enrichment	ALPL	1.94
124	Pompe disease, infantile-onset	Enrichment	PIK3CA	1.94
125	Langerhans cell histiocytosis	Enrichment	MAP2K1	1.94
126	Osteogenic sarcoma	Enrichment	TP53	1.94
127	Psoriatic arthritis	Enrichment	TNF	1.94
128	Nasopharyngeal carcinoma	Enrichment	TP53	1.94
129	Congenital lipomatous overgrowth, vascular malformations, and epidermal nevi	Enrichment	PIK3CA	1.94
130	Caffey disease	Enrichment	COL1A1	1.94
131	Atypical teratoid rhabdoid tumor	Enrichment	TP53	1.94
132	Anaplastic astrocytoma	Enrichment	TP53	1.94
133	Squamous cell carcinoma	Enrichment	TP53	1.94
134	Adenocarcinoma	Enrichment	TP53	1.94
135	Migraine without aura	Enrichment	TNF	1.94
136	Bone osteosarcoma	Enrichment	TP53	1.94
137	High bone mass osteogenesis imperfecta	Enrichment	COL1A1	1.94
138	Tricuspid valve insufficiency	Enrichment	PTPN11	1.94
139	Keratoacanthoma	Enrichment	PIK3CA	1.94
140	Gastric cancer	Enrichment	PIK3CA, TP53	1.93
141	Thrombocytopenia	Enrichment	PTPN11, SRC	1.84
142	Mirror movements 1	Enrichment	NTN1	1.82
143	Ehlers-danlos syndrome, arthrochalasia type, 1	Enrichment	COL1A1	1.82
144	Small cell cancer of the lung	Enrichment	TP53	1.82
145	Phenylketonuria	Enrichment	COL1A1	1.82
146	Thyroid cancer, nonmedullary, 1	Enrichment	TP53	1.82
147	Neurofibromatosis-noonan syndrome	Enrichment	MAP2K2	1.82
148	Megalencephaly-capillary malformation-polymicrogyria syndrome	Enrichment	PIK3CA	1.82
149	Chromosome 22q11.2 deletion syndrome, distal	Enrichment	MAPK1	1.82
150	Epidermolysis bullosa simplex 5c, with pyloric atresia	Enrichment	ITGB4	1.82
151	Lung sarcomatoid carcinoma	Enrichment	TP53	1.82
152	Malignant epithelioid hemangioendothelioma	Enrichment	YAP1	1.82
153	Cerebrovascular disease	Enrichment	PIK3CA	1.82
154	Embryonal rhabdomyosarcoma	Enrichment	TP53	1.82
155	Noonan syndrome-like disorder with or without juvenile myelomonocytic leukemia	Enrichment	PTPN11	1.82
156	Familial cerebral cavernous malformations	Enrichment	PIK3CA	1.82
157	Osteogenesis imperfecta with normal sclerae, dominant form	Enrichment	COL1A1	1.82
158	Hypertelorism	Enrichment	COL1A1, PIK3CA	1.77
159	Capillary malformations, congenital	Enrichment	PIK3CA	1.72
160	Epidermolysis bullosa simplex 1c, localized	Enrichment	ITGB4	1.72
161	Rhabdomyosarcoma 2	Enrichment	TP53	1.72
162	Aplasia cutis congenita	Enrichment	ITGB4	1.72
163	Vascular dementia	Enrichment	TNF	1.72
164	Acute megakaryocytic leukemia	Enrichment	TP53	1.72
165	Hemimegalencephaly	Enrichment	PIK3CA	1.72
166	Diffuse cutaneous systemic sclerosis	Enrichment	CCN2	1.72
167	Myeloma, multiple	Enrichment	TP53, YAP1	1.71
168	Ehlers-danlos syndrome, classic type, 1	Enrichment	COL1A1	1.64
169	Klippel-trenaunay-weber syndrome	Enrichment	PIK3CA	1.64
170	Li-fraumeni syndrome	Enrichment	TP53	1.64
171	Osteogenesis imperfecta, type i	Enrichment	COL1A1	1.64
172	Cowden syndrome 1	Enrichment	PIK3CA	1.64
173	Epidermolysis bullosa, junctional 1a, intermediate	Enrichment	ITGB4	1.64
174	Epidermolysis bullosa, junctional 5b, with pyloric atresia	Enrichment	ITGB4	1.64
175	Hemangioma, capillary infantile	Enrichment	KDR	1.64
176	Junctional epidermolysis bullosa non-herlitz type	Enrichment	ITGB4	1.64
177	Keratoconus	Enrichment	COL1A1	1.64
178	Patent ductus arteriosus	Enrichment	PTPN11	1.64
179	Adrenocortical carcinoma	Enrichment	TP53	1.64
180	Limited scleroderma	Enrichment	CCN2	1.64
181	Il10-related early-onset inflammatory bowel disease	Enrichment	IL10	1.64
182	Lung squamous cell carcinoma	Enrichment	PIK3CA	1.64
183	Classic ehlers-danlos syndrome	Enrichment	COL1A1	1.64
184	Esophageal cancer	Enrichment	TP53	1.58
185	Nevus, epidermal	Enrichment	PIK3CA	1.58
186	Osteogenesis imperfecta, type ii	Enrichment	COL1A1	1.58
187	Myelofibrosis	Enrichment	SRC	1.58
188	Squamous cell carcinoma, head and neck	Enrichment	TP53	1.58
189	Essential thrombocythemia	Enrichment	TP53	1.58
190	Pilomyxoid astrocytoma	Enrichment	RAF1	1.58
191	Epidermolysis bullosa simplex	Enrichment	ITGB4	1.58
192	B-lymphoblastic leukemia/lymphoma with t(9;22)(q34.1;q11.2)	Enrichment	TP53	1.58
193	Melanocytic nevus syndrome, congenital	Enrichment	RAF1	1.52
194	Glioma susceptibility 1	Enrichment	TP53	1.52
195	Lymphoma, non-hodgkin, familial	Enrichment	TP53	1.52
196	Rheumatoid arthritis	Enrichment	IL10	1.47
197	Neurodevelopmental disorder with dysmorphic facies and distal limb anomalies	Enrichment	RAC1	1.47
198	Junctional epidermolysis bullosa	Enrichment	ITGB4	1.47
199	Primary hyperaldosteronism	Enrichment	TP53	1.47
200	Leukemia, chronic lymphocytic	Enrichment	TP53	1.42
201	Familial colorectal cancer	Enrichment	TP53	1.42
202	Primary bone dysplasia	Enrichment	COL1A1	1.42
203	Pectus excavatum	Enrichment	PTPN11	1.38
204	Asthma	Enrichment	TNF	1.38
205	Myelodysplastic syndrome	Enrichment	TP53	1.38
206	Osteochondrodysplasia	Enrichment	COL1A1	1.38
207	Epicanthus	Enrichment	PTPN11	1.35
208	Juvenile myelomonocytic leukemia	Enrichment	PTPN11	1.35
209	Congenital long qt syndrome	Enrichment	PTPN11	1.35
210	Aortic valve disease 1	Enrichment	ROBO4	1.31
211	Microphthalmia/coloboma 12	Enrichment	YAP1	1.31
212	Diaphragmatic hernia, congenital	Enrichment	ROBO4	1.31
213	Osteogenesis imperfecta, type iv	Enrichment	COL1A1	1.31
214	Alzheimer's disease	Enrichment	TNF	1.31
215	Multiple sclerosis	Enrichment	ITGB4	1.28
216	Aortic aneurysm, familial thoracic 1	Enrichment	ROBO4	1.28
217	Lung cancer susceptibility 3	Enrichment	TP53	1.28
218	Coloboma of macula	Enrichment	YAP1	1.25
219	Osteogenesis imperfecta, type iii	Enrichment	COL1A1	1.25
220	Lynch syndrome	Enrichment	PIK3CA	1.25
221	Rhabdomyosarcoma	Enrichment	TP53	1.22
222	Gliosarcoma	Enrichment	TP53	1.22
223	Giant cell glioblastoma	Enrichment	TP53	1.20
224	Autism spectrum disorder	Enrichment	MAP2K1, PTPN11	1.18
225	Heart, malformation of	Enrichment	MAPK1	1.17
226	Patent foramen ovale	Enrichment	PTPN11	1.17
227	Behcet syndrome	Enrichment	IL10	1.15
228	Diffuse large b-cell lymphoma	Enrichment	TP53	1.15
229	Ehlers-danlos syndrome	Enrichment	COL1A1	1.15
230	Endometrial cancer	Enrichment	PIK3CA	1.11
231	Hepatoblastoma	Enrichment	TP53	1.11
232	Microcephaly	Enrichment	MAPK1, PTPN11	1.09
233	Skin disease	Enrichment	ITGB4	1.09
234	Diamond-blackfan anemia 1	Enrichment	TP53	1.07
235	Cardiomyopathy, familial hypertrophic, 1	Enrichment	RAF1	1.05
236	Inherited cancer-predisposing syndrome	Enrichment	PTPN11, TP53	1.04
237	Pancreatic cancer	Enrichment	TP53	1.04
238	Tetralogy of fallot	Enrichment	KDR	1.02
239	Hydrops fetalis, nonimmune	Enrichment	PTPN11	1.02
240	Strabismus	Enrichment	PTPN11	1.01
241	Long qt syndrome 1	Enrichment	PTPN11	0.96
242	Non-immune hydrops fetalis	Enrichment	PTPN11	0.95
243	Familial hypertrophic cardiomyopathy	Enrichment	RAF1	0.92
244	Left ventricular noncompaction	Enrichment	RAF1	0.90
245	Diamond-blackfan anemia	Enrichment	TP53	0.89
246	Leukemia, acute myeloid	Enrichment	TP53	0.85
247	Hypertrophic cardiomyopathy	Enrichment	PTPN11	0.82
248	Familial thoracic aortic aneurysm and aortic dissection	Enrichment	COL1A1	0.81
249	Familial isolated dilated cardiomyopathy	Enrichment	RAF1	0.73
250	Hereditary breast ovarian cancer syndrome	Enrichment	TP53	0.72
251	Male infertility with azoospermia or oligozoospermia due to single gene mutation	Enrichment	PTPN11	0.71
252	Primary ovarian insufficiency	Enrichment	KDR	0.69
253	Dilated cardiomyopathy	Enrichment	RAF1	0.58

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Netrin-UNC5B signaling pathway

Pathway Network for Netrin-UNC5B signaling pathway

Member Pathways for Netrin-UNC5B signaling pathway

Pathways in the Netrin-UNC5B signaling pathway SuperPath

Associated Genes for Netrin-UNC5B signaling pathway

Associated Disorders for Netrin-UNC5B signaling pathway

Disorders associated with Netrin-UNC5B signaling pathway SuperPath

STRING Interaction Network for Netrin-UNC5B signaling pathway

Sources for Netrin-UNC5B signaling pathway