NF-KappaB Family Pathway

No Pathway Network information available for NF-KappaB Family Pathway

Pathways in the NF-KappaB Family Pathway SuperPath

#	Name	Source	Genes
1	NF-KappaB Family Pathway	QIAGEN	AKT1 ANGPTL6 AREG BCL10 BCL3 BDNF BLK BMP1 BMP10 BMP2 BMP3 BMP4 BMP5 BMP6 BMP7 BMP8A BTC CARD10 CARD11 CARD14 CCN2 CD247 CD3E CD40 CD40LG CHUK CLEC11A CREBBP CRIPTO CXCL12 DRC4 EGF EGFR EIF2AK2 EP300 FADD FGF1 FGF10 FGF11 FGF12 FGF13 FGF14 FGF16 FGF17 FGF18 FGF19 FGF2 FGF20 FGF21 FGF22 FGF23 FGF4 FGF5 FGF6 FGF7 FGF8 FGFR1 FGFR2 FGFR3 FGFR4 FLT1 FLT4 FYN GAS1 GAS2 GAS6 GDF10 GDF15 GDF2 GDF5 GDF6 GDF9 GFER GH1 GH2 GHRH GMFG GNRH1 GNRH2 GPC6 HDGF HGF IGF1 IGF2 IGF2-AS IKBKB IKBKG IL1A IL1B IL1R1 IL1R2 IL2 IL3 IL6 IL9 IRAK1 IRAK2 IRAK3 IRAK4 KDR KITLG KLF10 LEFTY1 LEFTY2 LHB LTA LTB LTBP1 LTBP2 LTBP3 LTBP4 LTBR LYN MALT1 MAP3K14 MAP3K2 MAP3K3 MAP3K4 MAP3K5 MAP3K7 MDK MET MYD88 NFKB1 NFKB2 NFKBIA NFKBIB NFKBIE NGF NGFR NKIRAS1 NKIRAS2 NRG1 NRG2 NRG3 NTF3 NTF4 NUDT6 OGFR OGN PDGFA PDGFB PDGFC PDGFD PENK PGF PIK3R1 PIK3R2 PIK3R3 PIK3R4 PIK3R5 PLPP3 PPBP PRKCA PRKCB PRKCD PRKCE PRKCG PRKCH PRKCI PRKCQ PRKCZ PRKD1 PRKD3 PRKRA PROK1 PSIP1 PTN REL RELA RELB RIPK1 SEMA3A SEMA4B SEMA4G SEMA5A SPON1 TBRG1 TGFA TGFB1 TGFB2 TGFB3 THPO TIMP1 TIMP2 TIMP3 TIMP4 TLR1 TLR10 TLR2 TLR3 TLR4 TLR5 TLR6 TLR7 TLR8 TLR9 TNF TNFRSF13C TNFRSF1A TNFRSF1B TNFSF13B TOLLIP TRADD TRAF1 TRAF2 TRAF3 TRAF4 TRAF5 TRAF6 TYMP UTS2 VAV1 VAV2 VAV3 VEGFB VEGFC VEGFD ZAP70 (see all 219) (see less)
2	NF-KappaB (p50-p65) Pathway	QIAGEN	AKT1 ANGPTL6 AREG BDNF BMP1 BMP10 BMP2 BMP3 BMP4 BMP5 BMP6 BMP7 BMP8A BTC BTRC CALM1 CALM2 CALM3 CCN2 CHUK CLEC11A CREBBP CRIPTO CSNK2A1 CSNK2A2 CSNK2B CXCL12 DRC4 ECSIT EGF EGFR EP300 FADD FGF1 FGF10 FGF11 FGF12 FGF13 FGF14 FGF16 FGF17 FGF18 FGF19 FGF2 FGF20 FGF21 FGF22 FGF23 FGF4 FGF5 FGF6 FGF7 FGF8 FGFR1 FGFR2 FGFR3 FGFR4 FLT1 FLT4 GAS1 GAS2 GAS6 GDF10 GDF15 GDF2 GDF5 GDF6 GDF9 GFER GH1 GH2 GHRH GMFG GNRH1 GNRH2 GPC6 HDAC3 HDGF HGF IGF1 IGF2 IGF2-AS IKBKB IKBKE IKBKG IL1A IL1B IL1R1 IL1R2 IL2 IL3 IL6 IL9 IRAK1 IRAK2 IRAK3 IRAK4 KDR KITLG KLF10 LEFTY1 LEFTY2 LHB LTA LTBP1 LTBP2 LTBP3 LTBP4 MAP3K14 MAP3K2 MAP3K3 MAP3K4 MAP3K5 MAP3K7 MDK MET MYD88 NFKB1 NFKBIA NGF NGFR NRG1 NRG2 NRG3 NTF3 NTF4 NUDT6 OGFR OGN PDGFA PDGFB PDGFC PDGFD PENK PGF PIK3R1 PIK3R2 PIK3R3 PIK3R4 PIK3R5 PLPP3 PPBP PRKACA PRKACB PRKACG PRKAR1A PRKAR1B PRKAR2A PRKAR2B PROK1 PSIP1 PTN RELA RIPK1 SEMA3A SEMA4B SEMA4G SEMA5A SPON1 TBRG1 TGFA TGFB1 TGFB2 TGFB3 THPO TIMP1 TIMP2 TIMP3 TIMP4 TLR1 TLR10 TLR2 TLR3 TLR4 TLR5 TLR6 TLR7 TLR8 TLR9 TNF TNFAIP3 TNFRSF1A TNFRSF1B TOLLIP TRADD TRAF2 TRAF6 TYMP UBA52 UBB UBC UBD UTS2 VEGFB VEGFC VEGFD (see all 196) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	AKT1	AKT Serine/Threonine Kinase 1	Protein Coding	2
2	ANGPTL6	Angiopoietin Like 6	Protein Coding	2
3	AREG	Amphiregulin	Protein Coding	2
4	BDNF	Brain Derived Neurotrophic Factor	Protein Coding	2
5	BMP1	Bone Morphogenetic Protein 1	Protein Coding	2
6	BMP10	Bone Morphogenetic Protein 10	Protein Coding	2
7	BMP2	Bone Morphogenetic Protein 2	Protein Coding	2
8	BMP3	Bone Morphogenetic Protein 3	Protein Coding	2
9	BMP4	Bone Morphogenetic Protein 4	Protein Coding	2
10	BMP5	Bone Morphogenetic Protein 5	Protein Coding	2
11	BMP6	Bone Morphogenetic Protein 6	Protein Coding	2
12	BMP7	Bone Morphogenetic Protein 7	Protein Coding	2
13	BMP8A	Bone Morphogenetic Protein 8a	Protein Coding	2
14	BTC	Betacellulin	Protein Coding	2
15	CHUK	Component Of Inhibitor Of Nuclear Factor Kappa B Kinase Complex	Protein Coding	2
16	CREBBP	CREB Binding Lysine Acetyltransferase	Protein Coding	2
17	CCN2	Cellular Communication Network Factor 2	Protein Coding	2
18	CXCL12	C-X-C Motif Chemokine Ligand 12	Protein Coding	2
19	LEFTY2	Left-Right Determination Factor 2	Protein Coding	2
20	TYMP	Thymidine Phosphorylase	Protein Coding	2
21	EGF	Epidermal Growth Factor	Protein Coding	2
22	EGFR	Epidermal Growth Factor Receptor	Protein Coding	2
23	EP300	EP300 Lysine Acetyltransferase	Protein Coding	2
24	FADD	Fas Associated Via Death Domain	Protein Coding	2
25	FGF1	Fibroblast Growth Factor 1	Protein Coding	2
26	FGF10	Fibroblast Growth Factor 10	Protein Coding	2
27	FGF11	Fibroblast Growth Factor 11	Protein Coding	2
28	FGF12	Fibroblast Growth Factor 12	Protein Coding	2
29	FGF13	Fibroblast Growth Factor 13	Protein Coding	2
30	FGF14	Fibroblast Growth Factor 14	Protein Coding	2
31	FGF16	Fibroblast Growth Factor 16	Protein Coding	2
32	FGF17	Fibroblast Growth Factor 17	Protein Coding	2
33	FGF18	Fibroblast Growth Factor 18	Protein Coding	2
34	FGF19	Fibroblast Growth Factor 19	Protein Coding	2
35	FGF2	Fibroblast Growth Factor 2	Protein Coding	2
36	FGF20	Fibroblast Growth Factor 20	Protein Coding	2
37	FGF21	Fibroblast Growth Factor 21	Protein Coding	2
38	FGF22	Fibroblast Growth Factor 22	Protein Coding	2
39	FGF23	Fibroblast Growth Factor 23	Protein Coding	2
40	FGF4	Fibroblast Growth Factor 4	Protein Coding	2
41	FGF5	Fibroblast Growth Factor 5	Protein Coding	2
42	FGF6	Fibroblast Growth Factor 6	Protein Coding	2
43	FGF7	Fibroblast Growth Factor 7	Protein Coding	2
44	FGF8	Fibroblast Growth Factor 8	Protein Coding	2
45	FGFR1	Fibroblast Growth Factor Receptor 1	Protein Coding	2
46	FGFR2	Fibroblast Growth Factor Receptor 2	Protein Coding	2
47	FGFR3	Fibroblast Growth Factor Receptor 3	Protein Coding	2
48	FGFR4	Fibroblast Growth Factor Receptor 4	Protein Coding	2
49	VEGFD	Vascular Endothelial Growth Factor D	Protein Coding	2
50	FLT1	Fms Related Receptor Tyrosine Kinase 1	Protein Coding	2
51	FLT4	Fms Related Receptor Tyrosine Kinase 4	Protein Coding	2
52	GAS1	Growth Arrest Specific 1	Protein Coding	2
53	GAS2	Growth Arrest Specific 2	Protein Coding	2
54	GAS6	Growth Arrest Specific 6	Protein Coding	2
55	DRC4	Dynein Regulatory Complex Subunit 4	Protein Coding	2
56	GDF10	Growth Differentiation Factor 10	Protein Coding	2
57	GDF2	Growth Differentiation Factor 2	Protein Coding	2
58	GDF5	Growth Differentiation Factor 5	Protein Coding	2
59	GDF6	Growth Differentiation Factor 6	Protein Coding	2
60	GDF9	Growth Differentiation Factor 9	Protein Coding	2
61	GFER	Growth Factor, Augmenter Of Liver Regeneration	Protein Coding	2
62	GH1	Growth Hormone 1	Protein Coding	2
63	GH2	Growth Hormone 2	Protein Coding	2
64	GHRH	Growth Hormone Releasing Hormone	Protein Coding	2
65	GMFG	Glia Maturation Factor Gamma	Protein Coding	2
66	GNRH1	Gonadotropin Releasing Hormone 1	Protein Coding	2
67	GNRH2	Gonadotropin Releasing Hormone 2	Protein Coding	2
68	GPC6	Glypican 6	Protein Coding	2
69	HDGF	Heparin Binding Growth Factor	Protein Coding	2
70	HGF	Hepatocyte Growth Factor	Protein Coding	2
71	IGF1	Insulin Like Growth Factor 1	Protein Coding	2
72	IGF2	Insulin Like Growth Factor 2	Protein Coding	2
73	IGF2-AS	IGF2 Antisense RNA	RNA Gene	2
74	IKBKB	Inhibitor Of Nuclear Factor Kappa B Kinase Subunit Beta	Protein Coding	2
75	IKBKG	Inhibitor Of Nuclear Factor Kappa B Kinase Regulatory Subunit Gamma	Protein Coding	2
76	IL1A	Interleukin 1 Alpha	Protein Coding	2
77	IL1B	Interleukin 1 Beta	Protein Coding	2
78	IL1R1	Interleukin 1 Receptor Type 1	Protein Coding	2
79	IL1R2	Interleukin 1 Receptor Type 2	Protein Coding	2
80	IL2	Interleukin 2	Protein Coding	2
81	IL3	Interleukin 3	Protein Coding	2
82	IL6	Interleukin 6	Protein Coding	2
83	IL9	Interleukin 9	Protein Coding	2
84	IRAK1	Interleukin 1 Receptor Associated Kinase 1	Protein Coding	2
85	IRAK2	Interleukin 1 Receptor Associated Kinase 2	Protein Coding	2
86	IRAK3	Interleukin 1 Receptor Associated Kinase 3	Protein Coding	2
87	IRAK4	Interleukin 1 Receptor Associated Kinase 4	Protein Coding	2
88	KDR	Kinase Insert Domain Receptor	Protein Coding	2
89	KITLG	KIT Ligand	Protein Coding	2
90	LEFTY1	Left-Right Determination Factor 1	Protein Coding	2
91	LHB	Luteinizing Hormone Subunit Beta	Protein Coding	2
92	LTA	Lymphotoxin Alpha	Protein Coding	2
93	LTBP1	Latent Transforming Growth Factor Beta Binding Protein 1	Protein Coding	2
94	LTBP2	Latent Transforming Growth Factor Beta Binding Protein 2	Protein Coding	2
95	LTBP3	Latent Transforming Growth Factor Beta Binding Protein 3	Protein Coding	2
96	LTBP4	Latent Transforming Growth Factor Beta Binding Protein 4	Protein Coding	2
97	MAP3K14	Mitogen-Activated Protein Kinase Kinase Kinase 14	Protein Coding	2
98	MAP3K2	Mitogen-Activated Protein Kinase Kinase Kinase 2	Protein Coding	2
99	MAP3K3	Mitogen-Activated Protein Kinase Kinase Kinase 3	Protein Coding	2
100	MAP3K4	Mitogen-Activated Protein Kinase Kinase Kinase 4	Protein Coding	2
101	MAP3K5	Mitogen-Activated Protein Kinase Kinase Kinase 5	Protein Coding	2
102	MAP3K7	Mitogen-Activated Protein Kinase Kinase Kinase 7	Protein Coding	2
103	MDK	Midkine	Protein Coding	2
104	MET	MET Proto-Oncogene, Receptor Tyrosine Kinase	Protein Coding	2
105	MYD88	MYD88 Innate Immune Signal Transduction Adaptor	Protein Coding	2
106	NFKB1	Nuclear Factor Kappa B Subunit 1	Protein Coding	2
107	NFKBIA	NFKB Inhibitor Alpha	Protein Coding	2
108	NGF	Nerve Growth Factor	Protein Coding	2
109	NGFR	Nerve Growth Factor Receptor	Protein Coding	2
110	NRG1	Neuregulin 1	Protein Coding	2
111	NRG2	Neuregulin 2	Protein Coding	2
112	NRG3	Neuregulin 3	Protein Coding	2
113	NTF3	Neurotrophin 3	Protein Coding	2
114	NTF4	Neurotrophin 4	Protein Coding	2
115	NUDT6	Nudix Hydrolase 6	Protein Coding	2
116	OGFR	Opioid Growth Factor Receptor	Protein Coding	2
117	OGN	Osteoglycin	Protein Coding	2
118	PIK3R5	Phosphoinositide-3-Kinase Regulatory Subunit 5	Protein Coding	2
119	PDGFA	Platelet Derived Growth Factor Subunit A	Protein Coding	2
120	PDGFB	Platelet Derived Growth Factor Subunit B	Protein Coding	2
121	PDGFC	Platelet Derived Growth Factor C	Protein Coding	2
122	PENK	Proenkephalin	Protein Coding	2
123	PGF	Placental Growth Factor	Protein Coding	2
124	PIK3R1	Phosphoinositide-3-Kinase Regulatory Subunit 1	Protein Coding	2
125	PIK3R2	Phosphoinositide-3-Kinase Regulatory Subunit 2	Protein Coding	2
126	PIK3R3	Phosphoinositide-3-Kinase Regulatory Subunit 3	Protein Coding	2
127	PIK3R4	Phosphoinositide-3-Kinase Regulatory Subunit 4	Protein Coding	2
128	GDF15	Growth Differentiation Factor 15	Protein Coding	2
129	PLPP3	Phospholipid Phosphatase 3	Protein Coding	2
130	PPBP	Pro-Platelet Basic Protein	Protein Coding	2
131	PROK1	Prokineticin 1	Protein Coding	2
132	PSIP1	PC4 And SRSF1 Interacting Protein 1	Protein Coding	2
133	PTN	Pleiotrophin	Protein Coding	2
134	RELA	RELA Proto-Oncogene, NF-KB Subunit	Protein Coding	2
135	RIPK1	Receptor Interacting Serine/Threonine Kinase 1	Protein Coding	2
136	PDGFD	Platelet Derived Growth Factor D	Protein Coding	2
137	CLEC11A	C-Type Lectin Domain Containing 11A	Protein Coding	2
138	SEMA3A	Semaphorin 3A	Protein Coding	2
139	SEMA4B	Semaphorin 4B	Protein Coding	2
140	SEMA4G	Semaphorin 4G	Protein Coding	2
141	SEMA5A	Semaphorin 5A	Protein Coding	2
142	SPON1	Spondin 1	Protein Coding	2
143	TBRG1	Transforming Growth Factor Beta Regulator 1	Protein Coding	2
144	CRIPTO	Cripto, EGF-CFC Family Member	Protein Coding	2
145	TGFA	Transforming Growth Factor Alpha	Protein Coding	2
146	TGFB1	Transforming Growth Factor Beta 1	Protein Coding	2
147	TGFB2	Transforming Growth Factor Beta 2	Protein Coding	2
148	TGFB3	Transforming Growth Factor Beta 3	Protein Coding	2
149	THPO	Thrombopoietin	Protein Coding	2
150	KLF10	KLF Transcription Factor 10	Protein Coding	2
151	TIMP1	TIMP Metallopeptidase Inhibitor 1	Protein Coding	2
152	TIMP2	TIMP Metallopeptidase Inhibitor 2	Protein Coding	2
153	TIMP3	TIMP Metallopeptidase Inhibitor 3	Protein Coding	2
154	TIMP4	TIMP Metallopeptidase Inhibitor 4	Protein Coding	2
155	TLR1	Toll Like Receptor 1	Protein Coding	2
156	TLR10	Toll Like Receptor 10	Protein Coding	2
157	TLR2	Toll Like Receptor 2	Protein Coding	2
158	TLR3	Toll Like Receptor 3	Protein Coding	2
159	TLR4	Toll Like Receptor 4	Protein Coding	2
160	TLR5	Toll Like Receptor 5	Protein Coding	2
161	TLR6	Toll Like Receptor 6	Protein Coding	2
162	TLR7	Toll Like Receptor 7	Protein Coding	2
163	TLR8	Toll Like Receptor 8	Protein Coding	2
164	TLR9	Toll Like Receptor 9	Protein Coding	2
165	TNF	Tumor Necrosis Factor	Protein Coding	2
166	TNFRSF1A	TNF Receptor Superfamily Member 1A	Protein Coding	2
167	TNFRSF1B	TNF Receptor Superfamily Member 1B	Protein Coding	2
168	TOLLIP	Toll Interacting Protein	Protein Coding	2
169	TRADD	TNFRSF1A Associated Via Death Domain	Protein Coding	2
170	TRAF2	TNF Receptor Associated Factor 2	Protein Coding	2
171	TRAF6	TNF Receptor Associated Factor 6	Protein Coding	2
172	UTS2	Urotensin 2	Protein Coding	2
173	VEGFB	Vascular Endothelial Growth Factor B	Protein Coding	2
174	VEGFC	Vascular Endothelial Growth Factor C	Protein Coding	2
175	BCL10	BCL10 Immune Signaling Adaptor	Protein Coding	1
176	BCL3	BCL3 Transcription Coactivator	Protein Coding	1
177	BLK	BLK Proto-Oncogene, Src Family Tyrosine Kinase	Protein Coding	1
178	CARD10	Caspase Recruitment Domain Family Member 10	Protein Coding	1
179	CARD11	Caspase Recruitment Domain Family Member 11	Protein Coding	1
180	CARD14	Caspase Recruitment Domain Family Member 14	Protein Coding	1
181	CD3E	CD3 Epsilon Subunit Of T-Cell Receptor Complex	Protein Coding	1
182	CD247	CD247 Molecule	Protein Coding	1
183	FYN	FYN Proto-Oncogene, Src Family Tyrosine Kinase	Protein Coding	1
184	NKIRAS1	NFKB Inhibitor Interacting Ras Like 1	Protein Coding	1
185	NKIRAS2	NFKB Inhibitor Interacting Ras Like 2	Protein Coding	1
186	LTB	Lymphotoxin Beta	Protein Coding	1
187	LTBR	Lymphotoxin Beta Receptor	Protein Coding	1
188	LYN	LYN Proto-Oncogene, Src Family Tyrosine Kinase	Protein Coding	1
189	MALT1	MALT1 Paracaspase	Protein Coding	1
190	NFKB2	Nuclear Factor Kappa B Subunit 2	Protein Coding	1
191	NFKBIB	NFKB Inhibitor Beta	Protein Coding	1
192	NFKBIE	NFKB Inhibitor Epsilon	Protein Coding	1
193	PRKCA	Protein Kinase C Alpha	Protein Coding	1
194	PRKCB	Protein Kinase C Beta	Protein Coding	1
195	PRKCD	Protein Kinase C Delta	Protein Coding	1
196	PRKCE	Protein Kinase C Epsilon	Protein Coding	1
197	PRKCG	Protein Kinase C Gamma	Protein Coding	1
198	PRKCH	Protein Kinase C Eta	Protein Coding	1
199	PRKCI	Protein Kinase C Iota	Protein Coding	1
200	PRKD1	Protein Kinase D1	Protein Coding	1
201	PRKD3	Protein Kinase D3	Protein Coding	1
202	PRKCQ	Protein Kinase C Theta	Protein Coding	1
203	PRKCZ	Protein Kinase C Zeta	Protein Coding	1
204	EIF2AK2	Eukaryotic Translation Initiation Factor 2 Alpha Kinase 2	Protein Coding	1
205	PRKRA	Protein Activator Of Interferon Induced Protein Kinase EIF2AK2	Protein Coding	1
206	REL	REL Proto-Oncogene, NF-KB Subunit	Protein Coding	1
207	RELB	RELB Proto-Oncogene, NF-KB Subunit	Protein Coding	1
208	TNFRSF13C	TNF Receptor Superfamily Member 13C	Protein Coding	1
209	CD40	CD40 Molecule	Protein Coding	1
210	TNFSF13B	TNF Superfamily Member 13b	Protein Coding	1
211	CD40LG	CD40 Ligand	Protein Coding	1
212	TRAF1	TNF Receptor Associated Factor 1	Protein Coding	1
213	TRAF3	TNF Receptor Associated Factor 3	Protein Coding	1
214	TRAF4	TNF Receptor Associated Factor 4	Protein Coding	1
215	TRAF5	TNF Receptor Associated Factor 5	Protein Coding	1
216	VAV1	Vav Guanine Nucleotide Exchange Factor 1	Protein Coding	1
217	VAV2	Vav Guanine Nucleotide Exchange Factor 2	Protein Coding	1
218	VAV3	Vav Guanine Nucleotide Exchange Factor 3	Protein Coding	1
219	ZAP70	Zeta Chain Of T Cell Receptor Associated Protein Kinase 70	Protein Coding	1
220	BTRC	Beta-Transducin Repeat Containing E3 Ubiquitin Protein Ligase	Protein Coding	1
221	CALM1	Calmodulin 1	Protein Coding	1
222	CALM2	Calmodulin 2	Protein Coding	1
223	CALM3	Calmodulin 3	Protein Coding	1
224	CSNK2A1	Casein Kinase 2 Alpha 1	Protein Coding	1
225	CSNK2A2	Casein Kinase 2 Alpha 2	Protein Coding	1
226	CSNK2B	Casein Kinase 2 Beta	Protein Coding	1
227	HDAC3	Histone Deacetylase 3	Protein Coding	1
228	IKBKE	Inhibitor Of Nuclear Factor Kappa B Kinase Subunit Epsilon	Protein Coding	1
229	PRKACA	Protein Kinase CAMP-Activated Catalytic Subunit Alpha	Protein Coding	1
230	PRKACB	Protein Kinase CAMP-Activated Catalytic Subunit Beta	Protein Coding	1
231	PRKACG	Protein Kinase CAMP-Activated Catalytic Subunit Gamma	Protein Coding	1
232	PRKAR1A	Protein Kinase CAMP-Dependent Type I Regulatory Subunit Alpha	Protein Coding	1
233	PRKAR1B	Protein Kinase CAMP-Dependent Type I Regulatory Subunit Beta	Protein Coding	1
234	PRKAR2A	Protein Kinase CAMP-Dependent Type II Regulatory Subunit Alpha	Protein Coding	1
235	PRKAR2B	Protein Kinase CAMP-Dependent Type II Regulatory Subunit Beta	Protein Coding	1
236	ECSIT	ECSIT Signaling Integrator	Protein Coding	1
237	TNFAIP3	TNF Alpha Induced Protein 3	Protein Coding	1
238	UBA52	Ubiquitin A-52 Residue Ribosomal Protein Fusion Product 1	Protein Coding	1
239	UBB	Ubiquitin B	Protein Coding	1
240	UBC	Ubiquitin C	Protein Coding	1
241	UBD	Ubiquitin Like Modifier D	Protein Coding	1

Disorders associated with NF-KappaB Family Pathway SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Lacrimoauriculodentodigital syndrome 1	Enrichment	FGF10, FGFR2, FGFR3	5.53
2	Colorectal cancer	Enrichment	AKT1, BCL10, EP300, FGFR2, FGFR3, IGF2, MET, PIK3R1, TLR2	4.96
3	Gliosarcoma	Enrichment	EGFR, FGFR1, FGFR3, NFKBIA	4.17
4	Microform holoprosencephaly	Enrichment	CRIPTO, FGF8, FGFR1, GAS1	4.17
5	Lobar holoprosencephaly	Enrichment	CRIPTO, FGF8, FGFR1, GAS1	4.17
6	Testicular germ cell tumor	Enrichment	BCL10, FGFR3, KITLG	4.10
7	Giant cell glioblastoma	Enrichment	EGFR, FGFR1, FGFR3, NFKBIA	4.06
8	Semilobar holoprosencephaly	Enrichment	CRIPTO, FGF8, FGFR1, GAS1	3.96
9	Normosmic congenital hypogonadotropic hypogonadism	Enrichment	FGF17, FGF8, FGFR1, GNRH1	3.96
10	Common variable immunodeficiency	Enrichment	CD40LG, NFKB1, NFKB2	3.86
11	Catecholaminergic polymorphic ventricular tachycardia	Enrichment	CALM1, CALM2, CALM3	3.80
12	Severe combined immunodeficiency	Enrichment	CD247, CD3E, IKBKB, MALT1, ZAP70	3.76
13	Immunodeficiency 33	Enrichment	IKBKG, IRAK4	3.68
14	Pfeiffer syndrome	Enrichment	FGFR1, FGFR2	3.68
15	Jackson-weiss syndrome	Enrichment	FGFR1, FGFR2	3.68
16	Ectodermal dysplasia and immune deficiency	Enrichment	IKBKG, NFKBIA	3.68
17	Loeys-dietz syndrome 4	Enrichment	TGFB2, TGFB3	3.68
18	Transient predisposition to invasive pyogenic bacterial infection	Enrichment	IRAK4, MYD88	3.68
19	Kallmann syndrome	Enrichment	FGF17, FGF8, FGFR1, SEMA3A	3.52
20	Multisystem inflammatory syndrome in children	Enrichment	IRAK3, TLR3, TLR6, TRAF3	3.41
21	Crouzon syndrome	Enrichment	FGFR2, FGFR3	3.21
22	Psoriatic arthritis	Enrichment	LTA, TNF	3.21
23	T-b+ severe combined immunodeficiency due to cd3delta/cd3epsilon/cd3zeta	Enrichment	CD247, CD3E	3.11
24	Testicular cancer	Enrichment	BCL10, FGFR3	3.11
25	Septopreoptic holoprosencephaly	Enrichment	CRIPTO, FGF8, GAS1	2.92
26	Midline interhemispheric variant of holoprosencephaly	Enrichment	CRIPTO, FGF8, GAS1	2.92
27	Brachydactyly, type a2	Enrichment	BMP2, GDF5	2.91
28	Saethre-chotzen syndrome	Enrichment	FGFR2, FGFR3	2.91
29	Multiple synostoses syndrome	Enrichment	GDF5, GDF6	2.91
30	Alobar holoprosencephaly	Enrichment	CRIPTO, FGF8, GAS1	2.76
31	Hemifacial hyperplasia	Enrichment	FGFR2, FGFR3	2.69
32	Ventricular septal defect 1	Enrichment	BMP2, BMP7	2.69
33	Holoprosencephaly	Enrichment	FGF8, FGFR1	2.69
34	Systemic lupus erythematosus	Enrichment	IRAK1, TLR7, TNF, TNFAIP3	2.63
35	Arteriovenous malformations of the brain	Enrichment	EGFR, IL6, TIMP3	2.61
36	Lymphoma, mucosa-associated lymphoid type	Enrichment	BCL10, MALT1	2.60
37	Herpes simplex virus encephalitis	Enrichment	TLR3, TRAF3	2.60
38	Atrial septal defect 1	Enrichment	BMP2, TGFB2	2.52
39	Rubinstein-taybi syndrome 1	Enrichment	CREBBP, EP300	2.52
40	Holoprosencephaly 1	Enrichment	FGF8, FGFR1	2.52
41	Hemangioma, capillary infantile	Enrichment	FLT4, KDR	2.52
42	Chromosome 16p13.3 deletion syndrome, proximal	Enrichment	CREBBP, EP300	2.52
43	Inflammatory bowel disease 25, autosomal recessive	Enrichment	RIPK1, TGFB1	2.52
44	Il10-related early-onset inflammatory bowel disease	Enrichment	RIPK1, TGFB1	2.52
45	Lung squamous cell carcinoma	Enrichment	EGFR, FGFR3	2.52
46	Glaucoma, primary open angle	Enrichment	CARD10, LTBP2	2.43
47	Hemochromatosis, type 1	Enrichment	BMP2, BMP6	2.26
48	Charge syndrome	Enrichment	EP300, TNFRSF1A	2.16
49	Ellis-van creveld syndrome	Enrichment	PRKACA, PRKACB	2.16
50	Loeys-dietz syndrome	Enrichment	TGFB2, TGFB3	2.16
51	Marfan syndrome	Enrichment	LTBP2, TGFB2	2.06
52	Inflammatory bowel disease 1	Enrichment	IL6, PRKCQ	2.06
53	Long qt syndrome 1	Enrichment	CALM1, CALM2, CALM3	2.04
54	Renal hypodysplasia/aplasia 3	Enrichment	BMP4, FGFR3	1.90
55	Meningioma	Enrichment	AKT1, PDGFB	1.90
56	Myeloma, multiple	Enrichment	CREBBP, FGFR3, PIK3R2, TRAF5	1.90
57	Asthma	Enrichment	CARD11, TNF	1.89
58	Combined immunodeficiency	Enrichment	MALT1, ZAP70	1.89
59	Combined t cell and b cell immunodeficiency	Enrichment	MALT1, ZAP70	1.89
60	Combined t and b cell immunodeficiency	Enrichment	MALT1, ZAP70	1.89
61	Periodic fever, familial, autosomal dominant	Enrichment	TNFRSF1A	1.84
62	Hypochondroplasia	Enrichment	FGFR3	1.84
63	Proteus syndrome	Enrichment	AKT1	1.84
64	Beare-stevenson cutis gyrata syndrome	Enrichment	FGFR2	1.84
65	Osteoglophonic dysplasia	Enrichment	FGFR1	1.84
66	Acrodysostosis 1 with or without hormone resistance	Enrichment	PRKAR1A	1.84
67	Cardiospondylocarpofacial syndrome	Enrichment	MAP3K7	1.84
68	Thanatophoric dysplasia, type i	Enrichment	FGFR3	1.84
69	Microspherophakia and/or megalocornea, with ectopia lentis and with or without secondary glaucoma	Enrichment	LTBP2	1.84
70	Leprosy 3	Enrichment	TLR2	1.84
71	Trigonocephaly 1	Enrichment	FGFR1	1.84
72	Spinocerebellar ataxia 27a	Enrichment	FGF14	1.84
73	Muenke syndrome	Enrichment	FGFR3	1.84
74	Incontinentia pigmenti	Enrichment	IKBKG	1.84
75	Legionnaire disease	Enrichment	TLR5	1.84
76	Autoinflammatory disease, systemic, x-linked	Enrichment	IKBKG	1.84
77	Hypomagnesemia 4, renal	Enrichment	EGF	1.84
78	Immunodeficiency 68	Enrichment	MYD88	1.84
79	Glaucoma 3, primary congenital, d	Enrichment	LTBP2	1.84
80	Microphthalmia, isolated 4	Enrichment	GDF6	1.84
81	Angel-shaped phalangoepiphyseal dysplasia	Enrichment	GDF5	1.84
82	Leprosy 4	Enrichment	LTA	1.84
83	Deafness, autosomal recessive 39	Enrichment	HGF	1.84
84	Carney complex, type 1	Enrichment	PRKAR1A	1.84
85	Scaphocephaly, maxillary retrusion, and impaired intellectual development	Enrichment	FGFR2	1.84
86	Macroglobulinemia, waldenstrom 1	Enrichment	MYD88	1.84
87	Apert syndrome	Enrichment	FGFR2	1.84
88	Basal ganglia calcification, idiopathic, 5	Enrichment	PDGFB	1.84
89	Hyperpigmentation with or without hypopigmentation, familial progressive	Enrichment	KITLG	1.84
90	Immunodeficiency 83 viral infections	Enrichment	TLR3	1.84
91	Thanatophoric dysplasia, type ii	Enrichment	FGFR3	1.84
92	Leprosy 5	Enrichment	TLR1	1.84
93	Hypogonadotropic hypogonadism 20 with or without anosmia	Enrichment	FGF17	1.84
94	Fetal encasement syndrome	Enrichment	CHUK	1.84
95	Ciliary dyskinesia, primary, 33	Enrichment	DRC4	1.84
96	Camptodactyly, tall stature, and hearing loss syndrome	Enrichment	FGFR3	1.84
97	Frontometaphyseal dysplasia 2	Enrichment	MAP3K7	1.84
98	Ataxia-oculomotor apraxia 3	Enrichment	PIK3R5	1.84
99	Hypogonadotropic hypogonadism 23 with or without anosmia	Enrichment	LHB	1.84
100	Aplasia of lacrimal and salivary glands	Enrichment	FGF10	1.84
101	Bent bone dysplasia syndrome 1	Enrichment	FGFR2	1.84
102	Weill-marchesani syndrome 3	Enrichment	LTBP2	1.84
103	Immunodeficiency 15b	Enrichment	IKBKB	1.84
104	Multiple synostoses syndrome 4	Enrichment	GDF6	1.84
105	Immunodeficiency 15a	Enrichment	IKBKB	1.84
106	Intellectual developmental disorder, x-linked 110	Enrichment	FGF13	1.84
107	Spinocerebellar ataxia 27b, late-onset	Enrichment	FGF14	1.84
108	Hyperemesis gravidarum	Enrichment	GDF15	1.84
109	Amegakaryocytic thrombocytopenia, congenital, 2	Enrichment	THPO	1.84
110	Deafness, autosomal recessive 125	Enrichment	GAS2	1.84
111	Short syndrome	Enrichment	PIK3R1	1.84
112	Immunodeficiency 74, covid19-related, x-linked	Enrichment	TLR7	1.84
113	Ectodermal dysplasia and immunodeficiency 1	Enrichment	IKBKG	1.84
114	Hereditary lymphedema id	Enrichment	VEGFC	1.84
115	Systemic lupus erythematosus 1	Enrichment	TLR5	1.84
116	Osteofibrous dysplasia	Enrichment	MET	1.84
117	X-linked immunodeficiency 74	Enrichment	TLR7	1.84
118	Microphthalmia, syndromic 6	Enrichment	BMP4	1.84
119	Systemic lupus erythematosus 17	Enrichment	TLR7	1.84
120	Developmental and epileptic encephalopathy 90	Enrichment	FGF13	1.84
121	Cardioacrofacial dysplasia 2	Enrichment	PRKACB	1.84
122	Orofacial cleft 11	Enrichment	BMP4	1.84
123	Metacarpal 4-5 fusion	Enrichment	FGF16	1.84
124	Lymphatic malformation 4	Enrichment	VEGFC	1.84
125	Myxoma, intracardiac	Enrichment	PRKAR1A	1.84
126	Chronic recurrent multifocal osteomyelitis 3	Enrichment	IL1R1	1.84
127	Lacrimoauriculodentodigital syndrome 3	Enrichment	FGF10	1.84
128	Familial isolated trichomegaly	Enrichment	FGF5	1.84
129	Asthma-related traits 5	Enrichment	IRAK3	1.84
130	Deafness, autosomal recessive 97	Enrichment	MET	1.84
131	Skin/hair/eye pigmentation, variation in, 7	Enrichment	KITLG	1.84
132	Crouzon syndrome with acanthosis nigricans	Enrichment	FGFR3	1.84
133	Camurati-engelmann disease 2	Enrichment	TGFB2	1.84
134	Geleophysic dysplasia 3	Enrichment	LTBP3	1.84
135	Autism 9	Enrichment	MET	1.84
136	Immunodeficiency 67	Enrichment	IRAK4	1.84
137	Glaucoma 1, open angle, o	Enrichment	NTF4	1.84
138	Iron overload	Enrichment	BMP6	1.84
139	Immunodeficiency 36 with lymphoproliferation	Enrichment	PIK3R1	1.84
140	Hypogonadotropic hypogonadism 12 with or without anosmia	Enrichment	GNRH1	1.84
141	Multiple sclerosis 5	Enrichment	TNFRSF1A	1.84
142	Immunodeficiency 90 with encephalopathy, functional hyposplenia, and hepatic dysfunction	Enrichment	FADD	1.84
143	Hypogonadotropic hypogonadism 16 with or without anosmia	Enrichment	SEMA3A	1.84
144	Leber congenital amaurosis 17	Enrichment	GDF6	1.84
145	Long qt syndrome 16	Enrichment	CALM3	1.84
146	Cowden syndrome 6	Enrichment	AKT1	1.84
147	Telangiectasia, hereditary hemorrhagic, type 5	Enrichment	GDF2	1.84
148	Hereditary thrombocytosis with transverse limb defect	Enrichment	THPO	1.84
149	Melioidosis	Enrichment	TLR5	1.84
150	Pigmented nodular adrenocortical disease, primary, 4	Enrichment	PRKACA	1.84
151	Agammaglobulinemia 7, autosomal recessive	Enrichment	PIK3R1	1.84
152	Macular degeneration, age-related, 10	Enrichment	TLR4	1.84
153	Hypogonadotropic hypogonadism 6 with or without anosmia	Enrichment	FGF8	1.84
154	Achondroplasia, severe, with developmental delay and acanthosis nigricans	Enrichment	FGFR3	1.84
155	Tumoral calcinosis, hyperphosphatemic, familial, 2	Enrichment	FGF23	1.84
156	Hartsfield syndrome	Enrichment	FGFR1	1.84
157	Congenital heart defects, multiple types, 7	Enrichment	FLT4	1.84
158	Loeys-dietz syndrome 5	Enrichment	TGFB3	1.84
159	Renal hypodysplasia/aplasia 2	Enrichment	FGF20	1.84
160	Cardioacrofacial dysplasia 1	Enrichment	PRKACA	1.84
161	Tnf receptor-associated periodic fever syndrome	Enrichment	TNFRSF1A	1.84
162	20p12.3 microdeletion syndrome	Enrichment	BMP2	1.84
163	Cutis laxa, autosomal recessive, type iie	Enrichment	LTBP1	1.84
164	Okur-chung neurodevelopmental syndrome	Enrichment	CSNK2A1	1.84
165	Bartsocas-papas syndrome 2	Enrichment	CHUK	1.84
166	Short stature, facial dysmorphism, and skeletal anomalies with or without cardiac anomalies 1	Enrichment	BMP2	1.84
167	Menke-hennekam syndrome 1	Enrichment	CREBBP	1.84
168	Developmental and epileptic encephalopathy 47	Enrichment	FGF12	1.84
169	Autoinflammation with episodic fever and lymphadenopathy	Enrichment	RIPK1	1.84
170	Premature ovarian failure 14	Enrichment	GDF9	1.84
171	Tufted angioma of skin	Enrichment	KDR	1.84
172	Deafness, autosomal dominant 69	Enrichment	KITLG	1.84
173	Thrombocytopenia 9	Enrichment	THPO	1.84
174	Arthrogryposis, distal, type 11	Enrichment	MET	1.84
175	Lacrimoauriculodentodigital syndrome 2	Enrichment	FGFR3	1.84
176	Long qt syndrome 15	Enrichment	CALM2	1.84
177	Short-rib thoracic dysplasia 22 without polydactyly	Enrichment	FGF4	1.84
178	Familial behcet-like autoinflammatory syndrome	Enrichment	TNFAIP3	1.84
179	Rubinstein-taybi syndrome due to 16p13.3 microdeletion	Enrichment	CREBBP	1.84
180	Craniodigital syndrome and intellectual disability syndrome	Enrichment	CSNK2B	1.84
181	Glaucoma secondary to spherophakia/ectopia lentis and megalocornea	Enrichment	LTBP2	1.84
182	Immunodeficiency 112	Enrichment	MAP3K14	1.84
183	Prkar1b-related neurodegenerative dementia with intermediate filaments	Enrichment	PRKAR1B	1.84
184	Cerebral cavernous malformations 5	Enrichment	MAP3K3	1.84
185	Spinocerebellar ataxia type 27b	Enrichment	FGF14	1.84
186	Fgfr3-related chondrodysplasia	Enrichment	FGFR3	1.84
187	Waldenstram macroglobulinemia	Enrichment	MYD88	1.84
188	Congenital primary lymphedema of gordon	Enrichment	VEGFC	1.84
189	Combined immunodeficiency-hypogammaglobulinemia-skeletal anomalies syndrome due to ikbka deficiency	Enrichment	CHUK	1.84
190	Camptodactyly-tall stature-scoliosis-hearing loss syndrome	Enrichment	FGFR3	1.84
191	Menke-hennekam syndrome	Enrichment	CREBBP	1.84
192	Familial progressive hyperpigmentation	Enrichment	KITLG	1.84
193	Hartsfield-bixler-demyer syndrome	Enrichment	FGFR1	1.84
194	Verrucous hemangioma	Enrichment	MAP3K3	1.84
195	Egf-related primary hypomagnesemia with intellectual disability	Enrichment	EGF	1.84
196	Non-syndromic unicoronal craniosynostosis	Enrichment	FGFR2	1.84
197	Familial progressive hyper- and hypopigmentation	Enrichment	KITLG	1.84
198	Interstitial lung disease specific to childhood	Enrichment	FGF10	1.84
199	Nik deficiency	Enrichment	MAP3K14	1.84
200	Pityriasis rubra pilaris	Enrichment	CARD14	1.79
201	Psoriasis 2	Enrichment	CARD14	1.79
202	Autoimmune lymphoproliferative syndrome, type iii	Enrichment	PRKCD	1.79
203	Immunodeficiency 89 and autoimmunity	Enrichment	CARD10	1.79
204	Immunodeficiency 92	Enrichment	REL	1.79
205	Immunodeficiency with hyper-igm, type 1	Enrichment	CD40LG	1.79
206	Leukoencephalopathy, developmental delay, and episodic neurologic regression syndrome	Enrichment	EIF2AK2	1.79
207	Immunodeficiency 48	Enrichment	ZAP70	1.79
208	Immunodeficiency 132a	Enrichment	TRAF3	1.79
209	Immunodeficiency 132b	Enrichment	TRAF3	1.79
210	Immunodeficiency 18	Enrichment	CD3E	1.79
211	Persistent polyclonal b-cell lymphocytosis	Enrichment	CARD11	1.79
212	Immunodeficiency 25	Enrichment	CD247	1.79
213	Spinocerebellar ataxia 14	Enrichment	PRKCG	1.79
214	Immunodeficiency with hyper-igm, type 3	Enrichment	CD40	1.79
215	Immunodeficiency 12	Enrichment	MALT1	1.79
216	Congenital heart defects and ectodermal dysplasia	Enrichment	PRKD1	1.79
217	Autoimmune disease, multisystem, infantile-onset, 2	Enrichment	ZAP70	1.79
218	Deficiency in anterior pituitary function - variable immunodeficiency syndrome	Enrichment	NFKB2	1.79
219	Immunodeficiency 53	Enrichment	RELB	1.79
220	Autoinflammatory disease, systemic, with vasculitis	Enrichment	LYN	1.79
221	Dystonia 33	Enrichment	EIF2AK2	1.79
222	Sezary's disease	Enrichment	BCL10	1.79
223	Cd40 ligand deficiency	Enrichment	CD40LG	1.79
224	Malignant epithelial tumor of salivary glands	Enrichment	PRKD1	1.79
225	Mucosa-associated lymphoma	Enrichment	BCL10	1.79
226	Zap70-related severe combined immunodeficiency	Enrichment	ZAP70	1.79
227	Lung cancer susceptibility 3	Enrichment	EGFR, FGF10	1.77
228	Rare genetic intellectual disability	Enrichment	CREBBP, EP300	1.72
229	Human immunodeficiency virus type 1	Enrichment	CXCL12, TLR3	1.56
230	Acromicric dysplasia	Enrichment	LTBP3	1.54
231	Cri-du-chat syndrome	Enrichment	SEMA5A	1.54
232	Lymphatic malformation 1	Enrichment	FLT4	1.54
233	Sorsby fundus dystrophy	Enrichment	TIMP3	1.54
234	Camurati-engelmann disease 1	Enrichment	TGFB1	1.54
235	Amelogenesis imperfecta, type ig	Enrichment	PRKAR1A	1.54
236	Trichomegaly	Enrichment	FGF5	1.54
237	Thumb deformity	Enrichment	CREBBP	1.54
238	Intracranial hypertension, idiopathic	Enrichment	FLT4	1.54
239	Kyphomelic dysplasia	Enrichment	CCN2	1.54
240	Omodysplasia 1	Enrichment	GPC6	1.54
241	Pulmonary hypoplasia, primary	Enrichment	FGF10	1.54
242	Dermatofibrosarcoma protuberans	Enrichment	PDGFB	1.54
243	Cervical cancer	Enrichment	FGFR3	1.54
244	Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy 2	Enrichment	PIK3R5	1.54
245	Parkinson disease 8, autosomal dominant	Enrichment	GDF6	1.54
246	Pigmented nodular adrenocortical disease, primary, 1	Enrichment	PRKAR1A	1.54
247	Ectodermal dysplasia and immunodeficiency 2	Enrichment	NFKBIA	1.54
248	Aural atresia, congenital	Enrichment	FGFR2	1.54
249	Ventricular tachycardia, catecholaminergic polymorphic, 4	Enrichment	CALM1	1.54
250	Keratosis, seborrheic	Enrichment	FGFR3	1.54
251	Multiple synostoses syndrome 2	Enrichment	GDF5	1.54
252	Encephalocraniocutaneous lipomatosis	Enrichment	FGFR1	1.54
253	Myopathy, mitochondrial progressive, with congenital cataract and developmental delay	Enrichment	GFER	1.54
254	Cutis laxa, autosomal recessive, type ic	Enrichment	LTBP4	1.54
255	Bleeding disorder, platelet-type, 19	Enrichment	PRKACG	1.54
256	Silver-russell syndrome 3	Enrichment	IGF2	1.54
257	Osteogenesis imperfecta, type xiii	Enrichment	BMP1	1.54
258	Angioma, tufted	Enrichment	KDR	1.54
259	Immunodeficiency, common variable, 12, with autoimmunity	Enrichment	NFKB1	1.54
260	Autoinflammatory syndrome, familial, behcet-like 1	Enrichment	TNFAIP3	1.54
261	Brachydactyly, type a1, c	Enrichment	GDF5	1.54
262	Long qt syndrome 14	Enrichment	CALM1	1.54
263	Symphalangism, proximal, 1b	Enrichment	GDF5	1.54
264	Antley-bixler syndrome without genital anomalies or disordered steroidogenesis	Enrichment	FGFR2	1.54
265	Spondyloepimetaphyseal dysplasia, li-shao-li type	Enrichment	CCN2	1.54
266	Marbach-schaaf neurodevelopmental syndrome	Enrichment	PRKAR1B	1.54
267	Waardenburg syndrome, type 2f	Enrichment	KITLG	1.54
268	Poirier-bienvenu neurodevelopmental syndrome	Enrichment	CSNK2B	1.54
269	Autoinflammatory disease, familial, behcet-like 3	Enrichment	RELA	1.54
270	Menke-hennekam syndrome 2	Enrichment	EP300	1.54
271	Usher syndrome, type iv	Enrichment	PRKAR1A	1.54
272	Inflammatory bowel disease, immunodeficiency, and encephalopathy	Enrichment	TGFB1	1.54
273	Kowarski syndrome	Enrichment	GH1	1.54
274	Immunodeficiency 127	Enrichment	TNF	1.54
275	Childhood hepatocellular carcinoma	Enrichment	MET	1.54
276	Rela fusion-positive ependymoma	Enrichment	RELA	1.54
277	Acute myeloid leukemia with kat6a-crebbp fusion	Enrichment	CREBBP	1.54
278	Split hand-foot malformation	Enrichment	FGFR2	1.54
279	Rosette-forming glioneuronal tumor	Enrichment	FGFR1	1.54
280	Leprosy 1	Enrichment	TLR6	1.54
281	Acrodysostosis	Enrichment	PRKAR1A	1.54
282	Papillary renal cell carcinoma	Enrichment	MET	1.54
283	Camurati-engelmann disease	Enrichment	TGFB1	1.54
284	Congenital dyserythropoietic anemia	Enrichment	IRAK4	1.54
285	Microphthalmia/coloboma 6	Enrichment	GDF6	1.54
286	Fibrolamellar carcinoma	Enrichment	PRKACA	1.54
287	Cervix carcinoma	Enrichment	FGFR3	1.54
288	Ciliary dyskinesia, primary, 18	Enrichment	PRKAR1B	1.54
289	Proximal symphalangism	Enrichment	GDF5	1.54
290	Hereditary lymphedema i	Enrichment	FLT4	1.54
291	Glucosephosphate dehydrogenase deficiency	Enrichment	IKBKG	1.54
292	Immunodeficiency 57 with autoinflammation	Enrichment	RIPK1	1.54
293	Craniosynostosis 7	Enrichment	BMP2	1.54
294	Congenital amegakaryocytic thrombocytopenia	Enrichment	THPO	1.54
295	Interfrontal craniofaciosynostosis	Enrichment	FGFR1	1.54
296	Intermittent hydrarthrosis	Enrichment	TNFRSF1A	1.54
297	Isolated primary pigmented nodular adrenocortical disease	Enrichment	PRKAR1A	1.54
298	Short stature due to growth hormone qualitative anomaly	Enrichment	GH1	1.54
299	Autosomal dominant nonsyndromic deafness	Enrichment	FGFR2	1.54
300	Growth delay due to insulin-like growth factor type 1 deficiency	Enrichment	IGF1	1.54
301	Common variable immunodeficiency 12	Enrichment	NFKB1	1.54
302	Silver-russell syndrome due to an imprinting defect of 11p15	Enrichment	IGF2	1.54
303	Oculootodental syndrome	Enrichment	FADD	1.54
304	Submucosal cleft palate	Enrichment	UBB	1.54
305	Cleft hard palate	Enrichment	UBB	1.54
306	Silver-russell syndrome due to 11p15 microduplication	Enrichment	IGF2	1.54
307	Behcet syndrome	Enrichment	TLR4, TNFRSF1A	1.52
308	Diffuse large b-cell lymphoma	Enrichment	CREBBP, MYD88	1.52
309	Maturity-onset diabetes of the young, type 11	Enrichment	BLK	1.49
310	Immunodeficiency 11a	Enrichment	CARD11	1.49
311	Immunodeficiency 37	Enrichment	BCL10	1.49
312	Immunodeficiency, common variable, 10	Enrichment	NFKB2	1.49
313	Dystonia 16	Enrichment	PRKRA	1.49
314	Diamond-blackfan anemia 12	Enrichment	NKIRAS1	1.49
315	Immunodeficiency 11b with atopic dermatitis	Enrichment	CARD11	1.49
316	Immunodeficiency, common variable, 4	Enrichment	TNFRSF13C	1.49
317	B-cell expansion with nfkb and t-cell anergy	Enrichment	CARD11	1.49
318	Craniosynostosis	Enrichment	FGFR2, FGFR3	1.48
319	Tooth agenesis	Enrichment	FGFR1, TGFA	1.40
320	Brachydactyly, type a1	Enrichment	GDF5	1.37
321	Achondroplasia	Enrichment	FGFR3	1.37
322	Brachydactyly, type c	Enrichment	GDF5	1.37
323	Prognathism, mandibular	Enrichment	CSNK2B	1.37
324	Hypogonadotropic hypogonadism 2 with or without anosmia	Enrichment	FGFR1	1.37
325	Larsen syndrome	Enrichment	FGFR3	1.37
326	Klippel-feil syndrome 1, autosomal dominant	Enrichment	GDF6	1.37
327	Exfoliation syndrome	Enrichment	LTBP2	1.37
328	Tumoral calcinosis, hyperphosphatemic, familial, 1	Enrichment	FGF23	1.37
329	Acromesomelic dysplasia 2a	Enrichment	GDF5	1.37
330	Thrombocythemia 1	Enrichment	THPO	1.37
331	Hypophosphatemic rickets, autosomal dominant	Enrichment	FGF23	1.37
332	Acromesomelic dysplasia 2c	Enrichment	GDF5	1.37
333	Acromesomelic dysplasia 2b	Enrichment	GDF5	1.37
334	Mycosis fungoides	Enrichment	TNFRSF1B	1.37
335	Uvula, bifid	Enrichment	UBB	1.37
336	Immunodeficiency 98 with autoinflammation, x-linked	Enrichment	TLR8	1.37
337	Muscular dystrophy, duchenne type	Enrichment	LTBP4	1.37
338	Transposition of the great arteries, dextro-looped	Enrichment	BMP2	1.37
339	Cleft soft palate	Enrichment	UBB	1.37
340	Nasopharyngeal carcinoma	Enrichment	NFKBIA	1.37
341	Congenital lipomatous overgrowth, vascular malformations, and epidermal nevi	Enrichment	PIK3R1	1.37
342	Chromosome 8p11 myeloproliferative syndrome	Enrichment	FGFR1	1.37
343	Dyskeratosis congenita, autosomal dominant 6	Enrichment	THPO	1.37
344	Neonatal nephrocutaneous inflammatory syndrome	Enrichment	EGFR	1.37
345	Immunodeficiency 14a with lymphoproliferation, autosomal dominant	Enrichment	PIK3R1	1.37
346	Weill-marchesani syndrome 1	Enrichment	LTBP2	1.37
347	Tethered spinal cord syndrome	Enrichment	CREBBP	1.37
348	Autosomal recessive cutis laxa type i	Enrichment	LTBP1	1.37
349	Isolated growth hormone deficiency, type ib	Enrichment	GH1	1.37
350	Hamartoma	Enrichment	FGFR3	1.37
351	Testicular germ cell cancer	Enrichment	FGFR3	1.37
352	Frontometaphyseal dysplasia	Enrichment	MAP3K7	1.37
353	Immunodeficiency 14	Enrichment	PIK3R1	1.37
354	Intraocular pressure quantitative trait locus	Enrichment	CREBBP	1.37
355	Migraine without aura	Enrichment	TNF	1.37
356	Spermatocytoma	Enrichment	FGFR3	1.37
357	High bone mass osteogenesis imperfecta	Enrichment	BMP1	1.37
358	Neonatal inflammatory skin and bowel disease	Enrichment	EGFR	1.37
359	Geleophysic dysplasia	Enrichment	LTBP3	1.37
360	Renal cell carcinoma	Enrichment	MET	1.37
361	Isolated klippel-feil syndrome	Enrichment	GDF6	1.37
362	Beckwith-wiedemann syndrome due to imprinting defect of 11p15	Enrichment	IGF2	1.37
363	Saczary syndrome	Enrichment	TNFRSF1B	1.37
364	Malaria	Enrichment	IKBKG, TNF	1.37
365	Mesothelioma, malignant	Enrichment	BCL10	1.32
366	Torsion dystonia 1	Enrichment	EIF2AK2	1.32
367	T-cell acute lymphoblastic leukemia	Enrichment	BCL10	1.32
368	Tetralogy of fallot	Enrichment	FLT4, KDR	1.27
369	Kaposi sarcoma	Enrichment	IL6	1.25
370	Isolated growth hormone deficiency, type ii	Enrichment	GH1	1.25
371	Anemia, autoimmune hemolytic	Enrichment	TLR8	1.25
372	Microtia-anotia	Enrichment	BMP5	1.25
373	Megalencephaly-capillary malformation-polymicrogyria syndrome	Enrichment	PIK3R2	1.25
374	Glaucoma 3, primary infantile, b	Enrichment	LTBP2	1.25
375	Megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome 1	Enrichment	PIK3R2	1.25
376	Carney complex variant	Enrichment	PRKAR1A	1.25
377	Arrhythmogenic right ventricular dysplasia, familial, 10	Enrichment	PRKAR1A	1.25
378	Enophthalmos	Enrichment	CSNK2B	1.25
379	Syndactyly	Enrichment	CSNK2B	1.25
380	Weill-marchesani syndrome	Enrichment	LTBP2	1.25
381	Cerebral malaria	Enrichment	TNF	1.25
382	Silver-russell syndrome due to a point mutation	Enrichment	IGF2	1.25
383	Non-syndromic bicoronal craniosynostosis	Enrichment	FGFR3	1.25
384	Pediatric systemic lupus erythematosus	Enrichment	IRAK1	1.25
385	Systemic-onset juvenile idiopathic arthritis	Enrichment	IL6	1.25
386	Glioma	Enrichment	FGFR2	1.25
387	Immunodeficiency, common variable, 1	Enrichment	NFKB2	1.20
388	Hereditary ataxia	Enrichment	PRKCG	1.20
389	Bladder cancer	Enrichment	EGFR, FGFR3	1.18
390	Ectodermal dysplasia 10a, hypohidrotic/hair/nail type, autosomal dominant	Enrichment	TRAF6	1.15
391	Arrhythmogenic right ventricular dysplasia, familial, 1	Enrichment	TGFB3	1.15
392	Anemia, congenital, nonspherocytic hemolytic, 1	Enrichment	IKBKG	1.15
393	Rheumatoid arthritis, systemic juvenile	Enrichment	IL6	1.15
394	Atrioventricular septal defect	Enrichment	BMP5	1.15
395	Insulin-like growth factor i	Enrichment	IGF1	1.15
396	Rubinstein-taybi syndrome 2	Enrichment	EP300	1.15
397	Congenital heart defects, multiple types, 4	Enrichment	BMP7	1.15
398	Pre-eclampsia	Enrichment	FLT1	1.15
399	Juvenile glaucoma	Enrichment	LTBP2	1.15
400	Arrhythmogenic right ventricular dysplasia 1	Enrichment	TGFB3	1.15
401	Vascular dementia	Enrichment	TNF	1.15
402	Diffuse cutaneous systemic sclerosis	Enrichment	CCN2	1.15
403	Primary hypereosinophilic syndrome	Enrichment	FGFR1	1.15
404	Familial cerebral saccular aneurysm	Enrichment	ANGPTL6	1.15
405	Long qt syndrome	Enrichment	CALM1, CALM2	1.13
406	Lung cancer	Enrichment	EGFR, MET	1.11
407	Follicular lymphoma	Enrichment	BCL10	1.11
408	Cowden syndrome 1	Enrichment	EGFR	1.08
409	Split-hand/foot malformation 1	Enrichment	FGFR2	1.08
410	Hemihyperplasia, isolated	Enrichment	IGF2	1.08
411	Wilms tumor, aniridia, genitourinary anomalies, and impaired intellectual development syndrome	Enrichment	BDNF	1.08
412	Type 1 diabetes mellitus	Enrichment	IL6	1.08
413	Dental anomalies and short stature	Enrichment	LTBP3	1.08
414	Anterior segment dysgenesis 5	Enrichment	BMP4	1.08
415	Mitochondrial dna depletion syndrome 1	Enrichment	TYMP	1.08
416	Ventricular tachycardia, catecholaminergic polymorphic, 1, with or without atrial dysfunction and/or dilated cardiomyopathy	Enrichment	CALM1	1.08
417	Adrenocortical carcinoma	Enrichment	PRKAR1A	1.08
418	Limited scleroderma	Enrichment	CCN2	1.08
419	Breast adenocarcinoma	Enrichment	AKT1	1.08
420	Hypertrichosis	Enrichment	CREBBP	1.08
421	46,xy disorder of sex development	Enrichment	FGFR3	1.08
422	Mucopolysaccharidosis, type iiia	Enrichment	CARD14	1.03
423	Mucopolysaccharidosis iii	Enrichment	CARD14	1.03
424	Nevus, epidermal	Enrichment	FGFR3	1.01
425	Glaucoma 3, primary congenital, a	Enrichment	LTBP2	1.01
426	Silver-russell syndrome 1	Enrichment	IGF2	1.01
427	Squamous cell carcinoma, head and neck	Enrichment	EGFR	1.01
428	Waardenburg syndrome, type 2e	Enrichment	KITLG	1.01
429	Renal cell carcinoma, papillary, 1	Enrichment	MET	1.01
430	Neuropathy, hereditary sensory and autonomic, type v	Enrichment	NGF	1.01
431	Essential thrombocythemia	Enrichment	THPO	1.01
432	Hereditary hemorrhagic telangiectasia	Enrichment	GDF2	1.01
433	Pilomyxoid astrocytoma	Enrichment	FGFR1	1.01
434	Overgrowth syndrome	Enrichment	PIK3R1	1.01
435	Hypophosphatemic rickets	Enrichment	FGF23	1.01
436	Oligoarticular juvenile idiopathic arthritis	Enrichment	CD247	0.97
437	Rheumatoid factor-negative juvenile idiopathic arthritis	Enrichment	CD247	0.97
438	Arthrogryposis, distal, type 1a	Enrichment	MET	0.96
439	Basal ganglia calcification, idiopathic, 1	Enrichment	PDGFB	0.96
440	Isolated growth hormone deficiency, type ia	Enrichment	GH1	0.96
441	Mitochondrial dna depletion syndrome 4b	Enrichment	TYMP	0.96
442	Catecholaminergic polymorphic ventricular tachycardia 1	Enrichment	CALM1	0.96
443	Isolated split hand-split foot malformation	Enrichment	BTRC	0.96
444	Lymphoma, non-hodgkin, familial	Enrichment	BCL10	0.91
445	Orofacial cleft 1	Enrichment	FGF10	0.91
446	Rheumatoid arthritis	Enrichment	TLR1	0.91
447	Coronary heart disease 5	Enrichment	IKBKG	0.91
448	Adult hepatocellular carcinoma	Enrichment	EGF	0.91
449	Hypogonadotropic hypogonadism	Enrichment	FGFR1	0.91
450	Congenital central hypoventilation syndrome	Enrichment	BDNF	0.91
451	Cowden syndrome	Enrichment	AKT1	0.91
452	Mitochondrial neurogastrointestinal encephalomyopathy	Enrichment	TYMP	0.91
453	Renal agenesis, bilateral	Enrichment	FGF20	0.91
454	Gastric cancer	Enrichment	FGFR2, IL1B	0.89
455	Familial thoracic aortic aneurysm and aortic dissection	Enrichment	TGFB2, TGFB3	0.88
456	Meier-gorlin syndrome 1	Enrichment	FGFR2	0.87
457	Peters-plus syndrome	Enrichment	BMP4	0.87
458	Ciliary dyskinesia, primary, 3	Enrichment	NFKB1	0.87
459	Stickler syndrome	Enrichment	BMP4	0.87
460	Autosomal non-syndromic agammaglobulinemia	Enrichment	PIK3R1	0.87
461	Primary bone dysplasia	Enrichment	FGFR3	0.87
462	Immune deficiency disease	Enrichment	RIPK1	0.83
463	Meningioma, familial	Enrichment	PDGFB	0.83
464	Osteochondrodysplasia	Enrichment	FGFR3	0.83
465	Lung non-small cell carcinoma	Enrichment	EGFR	0.83
466	Heritable pulmonary arterial hypertension	Enrichment	GDF2	0.83
467	Stroke, ischemic	Enrichment	PRKCH	0.82
468	Septooptic dysplasia	Enrichment	FGFR1	0.80
469	Cutis laxa	Enrichment	LTBP4	0.80
470	Inherited isolated arrhythmogenic ventricular dysplasia, biventricular variant	Enrichment	TGFB3	0.80
471	Inherited isolated arrhythmogenic cardiomyopathy, dominant-left variant	Enrichment	TGFB3	0.80
472	Lip and oral cavity carcinoma	Enrichment	EGFR	0.80
473	Pulmonary hypertension, primary, 1	Enrichment	GDF2	0.76
474	Acute promyelocytic leukemia	Enrichment	PRKAR1A	0.76
475	Alzheimer's disease	Enrichment	TNF	0.76
476	Amelogenesis imperfecta	Enrichment	LTBP3	0.76
477	Ovarian cancer	Enrichment	AKT1, EGFR, MET	0.75
478	Multiple sclerosis	Enrichment	TNFRSF1A	0.73
479	Hypogonadotropic hypogonadism 7 with or without anosmia	Enrichment	FGFR1	0.73
480	Heart disease	Enrichment	CREBBP	0.73
481	Generalized epilepsy with febrile seizures plus	Enrichment	FGF13	0.73
482	Cleft lip/palate	Enrichment	BMP4	0.73
483	Inherited isolated arrhythmogenic cardiomyopathy, dominant-right variant	Enrichment	TGFB3	0.73
484	Chromosome 1p36 deletion syndrome	Enrichment	PRKCZ	0.72
485	Renal cell carcinoma, nonpapillary	Enrichment	MET	0.71
486	Polydactyly, postaxial, type a1	Enrichment	EP300	0.71
487	Wilms tumor 1	Enrichment	IGF2	0.71
488	Corpus callosum, agenesis of	Enrichment	CREBBP	0.71
489	Osteogenesis imperfecta, type iii	Enrichment	BMP1	0.71
490	Hydrocephalus	Enrichment	FGFR2	0.71
491	Isolated corpus callosum agenesis	Enrichment	CREBBP	0.71
492	Intellectual disability-hypoplastic corpus callosum-preauricular tag syndrome	Enrichment	CREBBP	0.71
493	Primary ovarian insufficiency	Enrichment	BMP6, KDR	0.68
494	Sudden infant death syndrome	Enrichment	CALM2	0.66
495	Beckwith-wiedemann syndrome	Enrichment	IGF2	0.64
496	Ehlers-danlos syndrome	Enrichment	TGFB2	0.62
497	Macs syndrome	Enrichment	GDF6	0.60
498	Endometrial cancer	Enrichment	FGFR2	0.58
499	Hepatoblastoma	Enrichment	FGFR3	0.58
500	Hepatocellular carcinoma	Enrichment	MET	0.56
501	Myocardial infarction	Enrichment	LTA	0.56
502	Visceral heterotaxy	Enrichment	LEFTY2	0.56
503	Maturity-onset diabetes of the young	Enrichment	BLK	0.56
504	Brittle bone disorder	Enrichment	BMP1	0.55
505	Autoinflammatory disease	Enrichment	TNFRSF1A	0.53
506	Scoliosis	Enrichment	CREBBP	0.53
507	Breast cancer	Enrichment	AKT1, IL2	0.53
508	Inherited cancer-predisposing syndrome	Enrichment	EGFR, MET, PRKAR1A	0.53
509	Primary ciliary dyskinesia	Enrichment	DRC4, PRKAR1B	0.52
510	Hydrops fetalis, nonimmune	Enrichment	FLT4	0.50
511	Brugada syndrome	Enrichment	SEMA3A	0.50
512	Hirschsprung disease 1	Enrichment	NRG3	0.46
513	Non-immune hydrops fetalis	Enrichment	FLT4	0.44
514	Rare autosomal recessive non-syndromic sensorineural deafness type dfnb	Enrichment	HGF, MET	0.43
515	Cystic fibrosis	Enrichment	TGFB1	0.43
516	Connective tissue disease	Enrichment	FGFR3	0.43
517	Peripheral nervous system disease	Enrichment	NGF	0.43
518	Neuropathy	Enrichment	NGF	0.43
519	Cakut	Enrichment	GDF6	0.41
520	Congenital nervous system abnormality	Enrichment	CREBBP, FGFR3	0.34
521	Nervous system disease	Enrichment	CREBBP, FGFR3	0.34
522	Type 2 diabetes mellitus	Enrichment	IL6	0.34
523	Autism spectrum disorder	Enrichment	CSNK2A1, CSNK2B	0.33
524	Hereditary breast carcinoma	Enrichment	AKT1	0.32
525	Sensorineural hearing loss	Enrichment	HGF	0.30
526	Thrombocytopenia	Enrichment	THPO	0.30
527	Body mass index quantitative trait locus 11	Enrichment	BDNF	0.29
528	Autosomal dominant non-syndromic intellectual disability	Enrichment	CSNK2B	0.29
529	Hypertelorism	Enrichment	FGFR2	0.27
530	Rare autosomal dominant non-syndromic sensorineural deafness type dfna	Enrichment	KITLG	0.27
531	Hereditary breast ovarian cancer syndrome	Enrichment	RIPK1	0.26
532	Male infertility with azoospermia or oligozoospermia due to single gene mutation	Enrichment	FGF8	0.25
533	Undetermined early-onset epileptic encephalopathy	Enrichment	FGF12	0.25
534	Autism	Enrichment	CREBBP	0.19
535	Mitochondrial disease	Enrichment	GFER	0.14
536	Leber plus disease	Enrichment	GDF6	0.12
537	Microcephaly	Enrichment	EP300	0.08
538	Complex neurodevelopmental disorder	Enrichment	CSNK2A1	0.08
539	Hereditary retinal dystrophy	Enrichment	TIMP3	0.01
540	Fundus dystrophy	Enrichment	TIMP3	0.01

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

NF-KappaB Family Pathway

Pathway Network for NF-KappaB Family Pathway

Member Pathways for NF-KappaB Family Pathway

Pathways in the NF-KappaB Family Pathway SuperPath

Associated Genes for NF-KappaB Family Pathway

Associated Disorders for NF-KappaB Family Pathway

Disorders associated with NF-KappaB Family Pathway SuperPath

STRING Interaction Network for NF-KappaB Family Pathway

Sources for NF-KappaB Family Pathway