NGF processing

Sources:

#	Name	Source	Genes
1	NGF processing	Reactome	FURIN NGF PCSK5 PCSK6
2	Expression and Processing of Neurotrophins	Reactome	FURIN NGF PCSK5 PCSK6
3	Synthesis and processing of ENV and VPU	Reactome	FURIN

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	FURIN	Furin, Paired Basic Amino Acid Cleaving Enzyme	Protein Coding	3
2	NGF	Nerve Growth Factor	Protein Coding	2
3	PCSK6	Proprotein Convertase Subtilisin/Kexin Type 6	Protein Coding	2
4	PCSK5	Proprotein Convertase Subtilisin/Kexin Type 5	Protein Coding	2

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Human immunodeficiency virus infectious disease	Direct
2	Neuropathy, hereditary sensory and autonomic, type v	Enrichment	NGF	2.69
3	Peripheral nervous system disease	Enrichment	NGF	2.03
4	Neuropathy	Enrichment	NGF	2.03

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Pathway Network for NGF processing