Nicotinate metabolism

No Pathway Network information available for Nicotinate metabolism

Pathways in the Nicotinate metabolism SuperPath

#	Name	Source	Genes
1	Nicotinate metabolism	Reactome	BST1 CD38 NADK NADK2 NADSYN1 NAMPT NAPRT NAXD NAXE NMNAT1 NMNAT2 NMNAT3 NMRK1 NMRK2 NNMT NT5E NUDT12 PARP10 PARP14 PARP16 PARP4 PARP6 PARP8 PARP9 QPRT RNLS SLC22A13 SLC25A51 SLC5A8 (see all 29) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	NAMPT	Nicotinamide Phosphoribosyltransferase	Protein Coding	1
2	NAXE	NAD(P)HX Epimerase	Protein Coding	1
3	NADK2	NAD Kinase 2, Mitochondrial	Protein Coding	1
4	PARP4	Poly(ADP-Ribose) Polymerase Family Member 4	Protein Coding	1
5	SLC5A8	Solute Carrier Family 5 Member 8	Protein Coding	1
6	NMNAT2	Nicotinamide Nucleotide Adenylyltransferase 2	Protein Coding	1
7	QPRT	Quinolinate Phosphoribosyltransferase	Protein Coding	1
8	NMRK2	Nicotinamide Riboside Kinase 2	Protein Coding	1
9	NMNAT3	Nicotinamide Nucleotide Adenylyltransferase 3	Protein Coding	1
10	NNMT	Nicotinamide N-Methyltransferase	Protein Coding	1
11	NT5E	5''-Nucleotidase Ecto	Protein Coding	1
12	PARP14	Poly(ADP-Ribose) Polymerase Family Member 14	Protein Coding	1
13	PARP16	Poly(ADP-Ribose) Polymerase Family Member 16	Protein Coding	1
14	NMRK1	Nicotinamide Riboside Kinase 1	Protein Coding	1
15	NADSYN1	NAD Synthetase 1	Protein Coding	1
16	RNLS	Renalase, FAD Dependent Amine Oxidase	Protein Coding	1
17	NAXD	NAD(P)HX Dehydratase	Protein Coding	1
18	PARP6	Poly(ADP-Ribose) Polymerase Family Member 6	Protein Coding	1
19	NMNAT1	Nicotinamide Nucleotide Adenylyltransferase 1	Protein Coding	1
20	NADK	NAD Kinase	Protein Coding	1
21	BST1	Bone Marrow Stromal Cell Antigen 1	Protein Coding	1
22	PARP8	Poly(ADP-Ribose) Polymerase Family Member 8	Protein Coding	1
23	NUDT12	Nudix Hydrolase 12	Protein Coding	1
24	PARP9	Poly(ADP-Ribose) Polymerase Family Member 9	Protein Coding	1
25	PARP10	Poly(ADP-Ribose) Polymerase Family Member 10	Protein Coding	1
26	SLC25A51	Solute Carrier Family 25 Member 51	Protein Coding	1
27	NAPRT	Nicotinate Phosphoribosyltransferase	Protein Coding	1
28	SLC22A13	Solute Carrier Family 22 Member 13	Protein Coding	1
29	CD38	CD38 Molecule	Protein Coding	1

Disorders associated with Nicotinate metabolism SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Calcification of joints and arteries	Enrichment	NT5E	2.67
2	2,4-dienoyl-coa reductase deficiency	Enrichment	NADK2	2.67
3	Vertebral, cardiac, renal, and limb defects syndrome 3	Enrichment	NADSYN1	2.67
4	Spondyloepiphyseal dysplasia, sensorineural hearing loss, impaired intellectual development, and leber congenital amaurosis	Enrichment	NMNAT1	2.67
5	Leber congenital amaurosis 9	Enrichment	NMNAT1	2.37
6	Encephalopathy, progressive, early-onset, with brain edema and/or leukoencephalopathy, 2	Enrichment	NAXD	2.37
7	Encephalopathy, progressive, early-onset, with brain edema and/or leukoencephalopathy, 1	Enrichment	NAXE	2.37
8	Nad hx dehydratase deficiency	Enrichment	NAXD	2.37
9	Congenital nad deficiency disorder	Enrichment	NADSYN1	2.07
10	Diarrhea	Enrichment	NMNAT1	1.89
11	Cone dystrophy	Enrichment	NMNAT1	1.30
12	Cone-rod dystrophy 2	Enrichment	NMNAT1	0.87
13	Leber plus disease	Enrichment	NMNAT1	0.73
14	Hereditary retinal dystrophy	Enrichment	NMNAT1	0.33
15	Fundus dystrophy	Enrichment	NMNAT1	0.33

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Nicotinate metabolism

Pathway Network for Nicotinate metabolism

Member Pathways for Nicotinate metabolism

Pathways in the Nicotinate metabolism SuperPath

Associated Genes for Nicotinate metabolism

Associated Disorders for Nicotinate metabolism

Disorders associated with Nicotinate metabolism SuperPath

STRING Interaction Network for Nicotinate metabolism

Sources for Nicotinate metabolism