NIPBL role in DNA damage - Cornelia de Lange syndrome

No Pathway Network information available for NIPBL role in DNA damage - Cornelia de Lange syndrome

Pathways in the NIPBL role in DNA damage - Cornelia de Lange syndrome SuperPath

#	Name	Source	Genes
1	NIPBL role in DNA damage - Cornelia de Lange syndrome	WikiPathways	ATM ATR CBX3 H2AX MDC1 NIPBL RNF168 RNF8 (see all 8) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	H2AX	H2A.X Variant Histone	Protein Coding	1
2	RNF8	Ring Finger Protein 8	Protein Coding	1
3	ATR	ATR Checkpoint Kinase	Protein Coding	1
4	ATM	ATM Serine/Threonine Kinase	Protein Coding	1
5	NIPBL	NIPBL Cohesin Loading Factor	Protein Coding	1
6	RNF168	Ring Finger Protein 168	Protein Coding	1
7	MDC1	Mediator Of DNA Damage Checkpoint 1	Protein Coding	1
8	CBX3	Chromobox 3	Protein Coding	1

Disorders associated with NIPBL role in DNA damage - Cornelia de Lange syndrome SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Seckel syndrome 1	Enrichment	ATR	3.23
2	Riddle syndrome	Enrichment	RNF168	3.23
3	Cutaneous telangiectasia and cancer syndrome, familial	Enrichment	ATR	3.23
4	Endometrial serous adenocarcinoma	Enrichment	ATM	3.23
5	B-cell non-hodgkin lymphoma	Enrichment	ATM	3.23
6	Familial cutaneous telangiectasia and oropharyngeal predisposition cancer syndrome	Enrichment	ATR	3.23
7	Cardiac valvular dysplasia, x-linked	Enrichment	ATM	2.93
8	High grade glioma	Enrichment	ATM	2.93
9	Chromosome 5p13 duplication syndrome	Enrichment	NIPBL	2.93
10	T-cell prolymphocytic leukemia	Enrichment	ATM	2.93
11	Ataxia-telangiectasia	Enrichment	ATM	2.75
12	Polycythemia vera	Enrichment	ATM	2.75
13	Koolen-de vries syndrome	Enrichment	ATM	2.75
14	Adenocarcinoma	Enrichment	ATM	2.75
15	Mantle cell lymphoma	Enrichment	ATM	2.63
16	Oculomotor apraxia	Enrichment	ATM	2.63
17	Glioblastoma	Enrichment	ATM	2.53
18	Clear cell renal cell carcinoma	Enrichment	ATM	2.45
19	Renal cell carcinoma, papillary, 1	Enrichment	ATM	2.38
20	Brachydactyly	Enrichment	NIPBL	2.38
21	Vesicoureteral reflux	Enrichment	NIPBL	2.38
22	Cryptorchidism	Enrichment	NIPBL	2.33
23	Cornelia de lange syndrome 1	Enrichment	NIPBL	2.28
24	Cryptorchidism, unilateral or bilateral	Enrichment	NIPBL	2.28
25	Colonic benign neoplasm	Enrichment	ATM	2.28
26	Cornelia de lange syndrome	Enrichment	NIPBL	2.28
27	Lynch syndrome 1	Enrichment	ATM	2.23
28	Leukemia, chronic lymphocytic	Enrichment	ATM	2.23
29	Immune deficiency disease	Enrichment	ATM	2.19
30	Uterine corpus cancer	Enrichment	ATM	2.19
31	Familial colorectal cancer type x	Enrichment	ATM	2.19
32	Diaphragmatic hernia, congenital	Enrichment	NIPBL	2.12
33	Breast-ovarian cancer, familial 1	Enrichment	ATM	2.12
34	Seckel syndrome	Enrichment	ATR	2.08
35	Renal cell carcinoma, nonpapillary	Enrichment	ATM	2.05
36	Gliosarcoma	Enrichment	ATM	2.03
37	Cleft palate, isolated	Enrichment	NIPBL	2.00
38	Giant cell glioblastoma	Enrichment	ATM	2.00
39	Endometrial cancer	Enrichment	ATM	1.91
40	Pancreatic cancer	Enrichment	ATM	1.83
41	Tetralogy of fallot	Enrichment	NIPBL	1.82
42	Bladder cancer	Enrichment	ATM	1.77
43	Prostate cancer	Enrichment	ATM	1.77
44	Gastric cancer	Enrichment	ATM	1.60
45	Hereditary breast carcinoma	Enrichment	ATM	1.59
46	Hereditary breast ovarian cancer syndrome	Enrichment	ATM	1.50
47	Myeloma, multiple	Enrichment	ATM	1.49
48	Breast cancer	Enrichment	ATM	1.36
49	Colorectal cancer	Enrichment	ATM	1.30
50	Ovarian cancer	Enrichment	ATM	1.24
51	Microcephaly	Enrichment	NIPBL	1.15
52	Inherited cancer-predisposing syndrome	Enrichment	ATM	1.12

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

NIPBL role in DNA damage - Cornelia de Lange syndrome

Pathway Network for NIPBL role in DNA damage - Cornelia de Lange syndrome

Member Pathways for NIPBL role in DNA damage - Cornelia de Lange syndrome

Pathways in the NIPBL role in DNA damage - Cornelia de Lange syndrome SuperPath

Associated Genes for NIPBL role in DNA damage - Cornelia de Lange syndrome

Associated Disorders for NIPBL role in DNA damage - Cornelia de Lange syndrome

Disorders associated with NIPBL role in DNA damage - Cornelia de Lange syndrome SuperPath

STRING Interaction Network for NIPBL role in DNA damage - Cornelia de Lange syndrome

Sources for NIPBL role in DNA damage - Cornelia de Lange syndrome