NK1R-mediated Non-Apoptotic PCD

No Pathway Network information available for NK1R-mediated Non-Apoptotic PCD

#	Name	Source	Genes
1	NK1R-mediated Non-Apoptotic PCD	QIAGEN	ARRB2 MAP2K2 MAPK1 NR4A1 RAF1 TAC1 TACR1 (see all 7) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	ARRB2	Arrestin Beta 2	Protein Coding	1
2	MAP2K2	Mitogen-Activated Protein Kinase Kinase 2	Protein Coding	1
3	MAPK1	Mitogen-Activated Protein Kinase 1	Protein Coding	1
4	NR4A1	Nuclear Receptor Subfamily 4 Group A Member 1	Protein Coding	1
5	RAF1	Raf-1 Proto-Oncogene, Serine/Threonine Kinase	Protein Coding	1
6	TAC1	Tachykinin Precursor 1	Protein Coding	1
7	TACR1	Tachykinin Receptor 1	Protein Coding	1

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Noonan syndrome and noonan-related syndrome	Enrichment	MAP2K2, RAF1	4.62
2	Noonan syndrome 1	Enrichment	MAP2K2, RAF1	4.24
3	Rasopathy	Enrichment	MAP2K2, RAF1	4.13
4	Noonan syndrome 5	Enrichment	RAF1	3.29
5	Cardiomyopathy, dilated, 1nn	Enrichment	RAF1	3.29
6	Noonan syndrome 13	Enrichment	MAPK1	3.29
7	Leopard syndrome 2	Enrichment	RAF1	3.29
8	Cardiofaciocutaneous syndrome 4	Enrichment	MAP2K2	3.29
9	Trigonitis	Enrichment	RAF1	3.29
10	Tafro syndrome	Enrichment	MAP2K2	2.99
11	Cardiofaciocutaneous syndrome 1	Enrichment	MAP2K2	2.69
12	Neurofibromatosis-noonan syndrome	Enrichment	MAP2K2	2.69
13	Chromosome 22q11.2 deletion syndrome, distal	Enrichment	MAPK1	2.69
14	Cardiofaciocutaneous syndrome	Enrichment	MAP2K2	2.69
15	Noonan syndrome with multiple lentigines	Enrichment	RAF1	2.69
16	Noonan syndrome 3	Enrichment	RAF1	2.44
17	Pilomyxoid astrocytoma	Enrichment	RAF1	2.44
18	Melanocytic nevus syndrome, congenital	Enrichment	RAF1	2.38
19	Specific learning disability	Enrichment	MAPK1	2.25
20	Heart, malformation of	Enrichment	MAPK1	2.03
21	Cardiomyopathy, familial hypertrophic, 1	Enrichment	RAF1	1.91
22	Familial hypertrophic cardiomyopathy	Enrichment	RAF1	1.77
23	Left ventricular noncompaction	Enrichment	RAF1	1.75
24	Familial isolated dilated cardiomyopathy	Enrichment	RAF1	1.57
25	Dilated cardiomyopathy	Enrichment	RAF1	1.39
26	Microcephaly	Enrichment	MAPK1	1.21

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Pathway Network for NK1R-mediated Non-Apoptotic PCD