nNOS Signaling at Neuronal Synapses

No Pathway Network information available for nNOS Signaling at Neuronal Synapses

Pathways in the nNOS Signaling at Neuronal Synapses SuperPath

#	Name	Source	Genes
1	nNOS Signaling at Neuronal Synapses	QIAGEN	CALM1 CALM2 CALM3 DLG4 GRIN1 GRIN2A GRIN2B GRIN2C GRIN2D GRINA NOS1 NOS1AP PPP3CA PPP3CB PPP3CC PPP3R1 PPP3R2 PRKCA PRKCB PRKCD PRKCE PRKCG PRKCH PRKCI PRKCQ PRKCZ PRKD1 PRKD3 RASD1 (see all 29) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	CALM1	Calmodulin 1	Protein Coding	1
2	CALM2	Calmodulin 2	Protein Coding	1
3	CALM3	Calmodulin 3	Protein Coding	1
4	NOS1AP	Nitric Oxide Synthase 1 Adaptor Protein	Protein Coding	1
5	DLG4	Discs Large MAGUK Scaffold Protein 4	Protein Coding	1
6	GRIN1	Glutamate Ionotropic Receptor NMDA Type Subunit 1	Protein Coding	1
7	GRIN2A	Glutamate Ionotropic Receptor NMDA Type Subunit 2A	Protein Coding	1
8	GRIN2B	Glutamate Ionotropic Receptor NMDA Type Subunit 2B	Protein Coding	1
9	GRIN2C	Glutamate Ionotropic Receptor NMDA Type Subunit 2C	Protein Coding	1
10	GRIN2D	Glutamate Ionotropic Receptor NMDA Type Subunit 2D	Protein Coding	1
11	GRINA	Glutamate Ionotropic Receptor NMDA Type Subunit Associated Protein 1	Protein Coding	1
12	NOS1	Nitric Oxide Synthase 1	Protein Coding	1
13	PPP3CA	Protein Phosphatase 3 Catalytic Subunit Alpha	Protein Coding	1
14	PPP3CB	Protein Phosphatase 3 Catalytic Subunit Beta	Protein Coding	1
15	PPP3CC	Protein Phosphatase 3 Catalytic Subunit Gamma	Protein Coding	1
16	PPP3R1	Protein Phosphatase 3 Regulatory Subunit B, Alpha	Protein Coding	1
17	PPP3R2	Protein Phosphatase 3 Regulatory Subunit B, Beta	Protein Coding	1
18	PRKCA	Protein Kinase C Alpha	Protein Coding	1
19	PRKCB	Protein Kinase C Beta	Protein Coding	1
20	PRKCD	Protein Kinase C Delta	Protein Coding	1
21	PRKCE	Protein Kinase C Epsilon	Protein Coding	1
22	PRKCG	Protein Kinase C Gamma	Protein Coding	1
23	PRKCH	Protein Kinase C Eta	Protein Coding	1
24	PRKCI	Protein Kinase C Iota	Protein Coding	1
25	PRKD1	Protein Kinase D1	Protein Coding	1
26	PRKD3	Protein Kinase D3	Protein Coding	1
27	PRKCQ	Protein Kinase C Theta	Protein Coding	1
28	PRKCZ	Protein Kinase C Zeta	Protein Coding	1
29	RASD1	Ras Related Dexamethasone Induced 1	Protein Coding	1

Disorders associated with nNOS Signaling at Neuronal Synapses SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Long qt syndrome 1	Enrichment	CALM1, CALM2, CALM3, NOS1AP	6.35
2	Catecholaminergic polymorphic ventricular tachycardia	Enrichment	CALM1, CALM2, CALM3	6.31
3	Autosomal dominant non-syndromic intellectual disability	Enrichment	GRIN1, GRIN2B, PPP3CA	3.79
4	Long qt syndrome	Enrichment	CALM1, CALM2	2.70
5	Pyloric stenosis, infantile hypertrophic, 1	Enrichment	NOS1	2.67
6	Epilepsy, focal, with speech disorder and with or without impaired intellectual development	Enrichment	GRIN2A	2.67
7	Developmental and epileptic encephalopathy 27	Enrichment	GRIN2B	2.67
8	Autoimmune lymphoproliferative syndrome, type iii	Enrichment	PRKCD	2.67
9	Developmental and epileptic encephalopathy 91	Enrichment	PPP3CA	2.67
10	Arthrogryposis, cleft palate, craniosynostosis, and impaired intellectual development	Enrichment	PPP3CA	2.67
11	Nephrotic syndrome, type 22	Enrichment	NOS1AP	2.67
12	Neurodevelopmental disorder with or without hyperkinetic movements and seizures, autosomal recessive	Enrichment	GRIN1	2.67
13	Spinocerebellar ataxia 14	Enrichment	PRKCG	2.67
14	Intellectual developmental disorder, autosomal dominant 6, with or without seizures	Enrichment	GRIN2B	2.67
15	Long qt syndrome 16	Enrichment	CALM3	2.67
16	Developmental and epileptic encephalopathy 101	Enrichment	GRIN1	2.67
17	Neurodevelopmental disorder with or without hyperkinetic movements and seizures, autosomal dominant	Enrichment	GRIN1	2.67
18	Congenital heart defects and ectodermal dysplasia	Enrichment	PRKD1	2.67
19	Long qt syndrome 15	Enrichment	CALM2	2.67
20	Grin2b-related neurodevelopmental disorder	Enrichment	GRIN2B	2.67
21	Landau-kleffner syndrome	Enrichment	GRIN2A	2.67
22	Intellectual disability, autosomal dominant 8	Enrichment	GRIN1	2.67
23	Early-onset epileptic encephalopathy and intellectual disability due to grin2a mutation	Enrichment	GRIN2A	2.67
24	Grin2a-related disorders	Enrichment	GRIN2A	2.67
25	Malignant epithelial tumor of salivary glands	Enrichment	PRKD1	2.67
26	Epilepsy	Enrichment	GRIN2A, GRIN2B	2.49
27	Benign epilepsy with centrotemporal spikes	Enrichment	GRIN1, GRIN2A	2.46
28	Centralopathic epilepsy	Enrichment	GRIN1, GRIN2A	2.42
29	West syndrome	Enrichment	GRIN1, GRIN2B	2.40
30	Ventricular tachycardia, catecholaminergic polymorphic, 4	Enrichment	CALM1	2.37
31	Long qt syndrome 14	Enrichment	CALM1	2.37
32	Bilateral generalized polymicrogyria	Enrichment	GRIN1	2.37
33	Intellectual developmental disorder, autosomal dominant 21	Enrichment	GRIN2A	2.37
34	Developmental and epileptic encephalopathy 46	Enrichment	GRIN2D	2.37
35	Vulto-van silfhout-de vries syndrome	Enrichment	DLG4	2.37
36	Rolandic epilepsy-speech dyspraxia syndrome	Enrichment	GRIN2A	2.37
37	Epilepsy-aphasia spectrum	Enrichment	GRIN2A	2.37
38	Undetermined early-onset epileptic encephalopathy	Enrichment	GRIN2D, PPP3CA	2.20
39	Heart defects, congenital, and other congenital anomalies	Enrichment	DLG4	2.19
40	Auditory neuropathy and optic atrophy	Enrichment	GRIN2C	2.19
41	Intellectual developmental disorder, autosomal dominant 62	Enrichment	DLG4	2.19
42	Neurodevelopmental disorder with hypotonia and impaired expressive language and with or without seizures	Enrichment	DLG4	2.19
43	Dlg4-related synaptopathy	Enrichment	DLG4	2.19
44	Acyl-coa dehydrogenase, very long-chain, deficiency of	Enrichment	DLG4	2.07
45	Astigmatism	Enrichment	GRIN2B	2.07
46	Hereditary ataxia	Enrichment	PRKCG	2.07
47	Idiopathic achalasia	Enrichment	NOS1	2.07
48	Sleep disorder	Enrichment	GRIN2B	1.97
49	Ventricular tachycardia, catecholaminergic polymorphic, 1, with or without atrial dysfunction and/or dilated cardiomyopathy	Enrichment	CALM1	1.89
50	Catecholaminergic polymorphic ventricular tachycardia 1	Enrichment	CALM1	1.77
51	Inflammatory bowel disease 1	Enrichment	PRKCQ	1.72
52	Stroke, ischemic	Enrichment	PRKCH	1.67
53	Chromosome 1p36 deletion syndrome	Enrichment	PRKCZ	1.56
54	Complex neurodevelopmental disorder	Enrichment	DLG4, GRIN2B	1.54
55	Sudden infant death syndrome	Enrichment	CALM2	1.45
56	Early infantile developmental and epileptic encephalopathy	Enrichment	GRIN1	1.42
57	Craniosynostosis	Enrichment	GRIN2B	1.38
58	Scoliosis	Enrichment	GRIN2B	1.30
59	Developmental and epileptic encephalopathy 1	Enrichment	GRIN1	1.28
60	Cerebral palsy	Enrichment	GRIN2B	1.10
61	Autosomal recessive non-syndromic intellectual disability	Enrichment	GRIN1	0.93
62	Autism spectrum disorder	Enrichment	GRIN2B	0.68
63	Microcephaly	Enrichment	GRIN2B	0.63

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

nNOS Signaling at Neuronal Synapses

Pathway Network for nNOS Signaling at Neuronal Synapses

Member Pathways for nNOS Signaling at Neuronal Synapses

Pathways in the nNOS Signaling at Neuronal Synapses SuperPath

Associated Genes for nNOS Signaling at Neuronal Synapses

Associated Disorders for nNOS Signaling at Neuronal Synapses

Disorders associated with nNOS Signaling at Neuronal Synapses SuperPath

STRING Interaction Network for nNOS Signaling at Neuronal Synapses

Sources for nNOS Signaling at Neuronal Synapses