Non-genomic actions of 1,25 dihydroxyvitamin D3

No Pathway Network information available for Non-genomic actions of 1,25 dihydroxyvitamin D3

Pathways in the Non-genomic actions of 1,25 dihydroxyvitamin D3 SuperPath

#	Name	Source	Genes
1	Non-genomic actions of 1,25 dihydroxyvitamin D3	WikiPathways	CAMK2D CAMP CAV1 CCL2 CD40 CD40LG CXCL8 CYP24A1 CYP27B1 DEFB4A ETS1 HRAS IFI27L2 IFNA2 IFNAR2 IFNG IFNGR1 IFNGR2 IKBKB IL6 JUN KRAS MAPK1 MAPK11 MAPK12 MAPK13 MAPK14 MAPK7 MAPK8 MAPK9 MED1 NFKB1 NFKB2 NOD2 NRAS PLCG2 PRKCA PRKCB PRKCD PRKCG PRKCZ RELB RXRA RXRG SP1 SP3 STAT1 TLR4 TNF TNFRSF1A VDR (see all 51) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	IFNGR2	Interferon Gamma Receptor 2	Protein Coding	1
2	IFNGR1	Interferon Gamma Receptor 1	Protein Coding	1
3	IFNG	Interferon Gamma	Protein Coding	1
4	CAV1	Caveolin 1	Protein Coding	1
5	IFNAR2	Interferon Alpha And Beta Receptor Subunit 2	Protein Coding	1
6	IFNA2	Interferon Alpha 2	Protein Coding	1
7	CD40LG	CD40 Ligand	Protein Coding	1
8	CD40	CD40 Molecule	Protein Coding	1
9	CAMP	Cathelicidin Antimicrobial Peptide	Protein Coding	1
10	CAMK2D	Calcium/Calmodulin Dependent Protein Kinase II Delta	Protein Coding	1
11	VDR	Vitamin D Receptor	Protein Coding	1
12	TNFRSF1A	TNF Receptor Superfamily Member 1A	Protein Coding	1
13	TNF	Tumor Necrosis Factor	Protein Coding	1
14	TLR4	Toll Like Receptor 4	Protein Coding	1
15	STAT1	Signal Transducer And Activator Of Transcription 1	Protein Coding	1
16	SP1	Sp1 Transcription Factor	Protein Coding	1
17	NOD2	Nucleotide Binding Oligomerization Domain Containing 2	Protein Coding	1
18	CCL2	C-C Motif Chemokine Ligand 2	Protein Coding	1
19	RXRG	Retinoid X Receptor Gamma	Protein Coding	1
20	RXRA	Retinoid X Receptor Alpha	Protein Coding	1
21	RELB	RELB Proto-Oncogene, NF-KB Subunit	Protein Coding	1
22	MAPK13	Mitogen-Activated Protein Kinase 13	Protein Coding	1
23	MAPK9	Mitogen-Activated Protein Kinase 9	Protein Coding	1
24	MAPK11	Mitogen-Activated Protein Kinase 11	Protein Coding	1
25	MAPK8	Mitogen-Activated Protein Kinase 8	Protein Coding	1
26	MAPK7	Mitogen-Activated Protein Kinase 7	Protein Coding	1
27	MAPK1	Mitogen-Activated Protein Kinase 1	Protein Coding	1
28	PRKCZ	Protein Kinase C Zeta	Protein Coding	1
29	PRKCG	Protein Kinase C Gamma	Protein Coding	1
30	PRKCD	Protein Kinase C Delta	Protein Coding	1
31	PRKCB	Protein Kinase C Beta	Protein Coding	1
32	PRKCA	Protein Kinase C Alpha	Protein Coding	1
33	MED1	Mediator Complex Subunit 1	Protein Coding	1
34	PLCG2	Phospholipase C Gamma 2	Protein Coding	1
35	NRAS	NRAS Proto-Oncogene, GTPase	Protein Coding	1
36	NFKB2	Nuclear Factor Kappa B Subunit 2	Protein Coding	1
37	NFKB1	Nuclear Factor Kappa B Subunit 1	Protein Coding	1
38	KRAS	KRAS Proto-Oncogene, GTPase	Protein Coding	1
39	JUN	Jun Proto-Oncogene, AP-1 Transcription Factor Subunit	Protein Coding	1
40	CXCL8	C-X-C Motif Chemokine Ligand 8	Protein Coding	1
41	IL6	Interleukin 6	Protein Coding	1
42	IKBKB	Inhibitor Of Nuclear Factor Kappa B Kinase Subunit Beta	Protein Coding	1
43	HRAS	HRas Proto-Oncogene, GTPase	Protein Coding	1
44	ETS1	ETS Proto-Oncogene 1, Transcription Factor	Protein Coding	1
45	DEFB4A	Defensin Beta 4A	Protein Coding	1
46	CYP27B1	Cytochrome P450 Family 27 Subfamily B Member 1	Protein Coding	1
47	CYP24A1	Cytochrome P450 Family 24 Subfamily A Member 1	Protein Coding	1
48	MAPK14	Mitogen-Activated Protein Kinase 14	Protein Coding	1
49	IFI27L2	Interferon Alpha Inducible Protein 27 Like 2	Protein Coding	1
50	SP3	Sp3 Transcription Factor	Protein Coding	1
51	MAPK12	Mitogen-Activated Protein Kinase 12	Protein Coding	1

Disorders associated with Non-genomic actions of 1,25 dihydroxyvitamin D3 SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Schimmelpenning-feuerstein-mims syndrome	Enrichment	HRAS, KRAS, NRAS	6.70
2	Behcet syndrome	Enrichment	IFNGR1, NOD2, TLR4, TNFRSF1A	6.18
3	Nevus, epidermal	Enrichment	HRAS, KRAS, NRAS	5.76
4	Common variable immunodeficiency	Enrichment	CD40LG, NFKB1, NFKB2	5.76
5	Lung non-small cell carcinoma	Enrichment	HRAS, KRAS, NRAS	5.09
6	Ras-associated autoimmune leukoproliferative disorder	Enrichment	KRAS, NRAS	4.86
7	Noonan syndrome and noonan-related syndrome	Enrichment	HRAS, KRAS, NRAS	4.66
8	Large congenital melanocytic nevus	Enrichment	HRAS, NRAS	4.38
9	Chronic myelogenous leukemia, bcr-abl1 positive	Enrichment	KRAS, NRAS	4.08
10	Hepatitis b	Enrichment	IFNAR2, IFNGR1	4.08
11	Noonan syndrome 1	Enrichment	HRAS, KRAS, NRAS	4.08
12	Rasopathy	Enrichment	HRAS, KRAS, NRAS	3.91
13	Differentiated thyroid carcinoma	Enrichment	HRAS, KRAS, NRAS	3.77
14	Thyroid cancer, nonmedullary, 2	Enrichment	HRAS, NRAS	3.54
15	Leukemia, chronic myeloid	Enrichment	KRAS, NRAS	3.54
16	Noonan syndrome 3	Enrichment	HRAS, KRAS	3.54
17	Follicular thyroid carcinoma	Enrichment	HRAS, NRAS	3.54
18	Melanocytic nevus syndrome, congenital	Enrichment	HRAS, NRAS	3.42
19	Inflammatory bowel disease 1	Enrichment	IL6, NOD2	3.31
20	Juvenile myelomonocytic leukemia	Enrichment	KRAS, NRAS	3.05
21	Multiple sclerosis	Enrichment	CYP27B1, TNFRSF1A	2.91
22	Human immunodeficiency virus type 1	Enrichment	CCL2, IFNG	2.69
23	Arteriovenous malformations of the brain	Enrichment	IL6, KRAS	2.64
24	Autoinflammatory disease	Enrichment	NOD2, TNFRSF1A	2.44
25	Periodic fever, familial, autosomal dominant	Enrichment	TNFRSF1A	2.42
26	Oculoectodermal syndrome	Enrichment	KRAS	2.42
27	Helicobacter pylori infection	Enrichment	IFNGR1	2.42
28	Lipodystrophy, congenital generalized, type 3	Enrichment	CAV1	2.42
29	Melanosis, neurocutaneous	Enrichment	NRAS	2.42
30	Noonan syndrome 6	Enrichment	NRAS	2.42
31	Blau syndrome	Enrichment	NOD2	2.42
32	Pulmonary hypertension, primary, 3	Enrichment	CAV1	2.42
33	Autoimmune lymphoproliferative syndrome, type iii	Enrichment	PRKCD	2.42
34	Immunodeficiency 27a	Enrichment	IFNGR1	2.42
35	Immunodeficiency 15b	Enrichment	IKBKB	2.42
36	Immunodeficiency 69	Enrichment	IFNG	2.42
37	Noonan syndrome 13	Enrichment	MAPK1	2.42
38	Immunodeficiency 15a	Enrichment	IKBKB	2.42
39	Immunodeficiency with hyper-igm, type 1	Enrichment	CD40LG	2.42
40	Lipodystrophy, familial partial, type 7	Enrichment	CAV1	2.42
41	Cardiofaciocutaneous syndrome 2	Enrichment	KRAS	2.42
42	Immunodeficiency 27b	Enrichment	IFNGR1	2.42
43	Spinocerebellar ataxia 14	Enrichment	PRKCG	2.42
44	Immunodeficiency with hyper-igm, type 3	Enrichment	CD40	2.42
45	Immunodeficiency 31a	Enrichment	STAT1	2.42
46	Multiple sclerosis 5	Enrichment	TNFRSF1A	2.42
47	Autoinflammation, antibody deficiency, and immune dysregulation	Enrichment	PLCG2	2.42
48	Macular degeneration, age-related, 10	Enrichment	TLR4	2.42
49	Immunodeficiency 31b	Enrichment	STAT1	2.42
50	Familial cold autoinflammatory syndrome 3	Enrichment	PLCG2	2.42
51	Tnf receptor-associated periodic fever syndrome	Enrichment	TNFRSF1A	2.42
52	Deficiency in anterior pituitary function - variable immunodeficiency syndrome	Enrichment	NFKB2	2.42
53	Immunodeficiency 53	Enrichment	RELB	2.42
54	Rickets	Enrichment	VDR	2.42
55	Congenital pulmonary airway malformation	Enrichment	KRAS	2.42
56	Cd40 ligand deficiency	Enrichment	CD40LG	2.42
57	Phakomatosis pigmentokeratotica	Enrichment	HRAS	2.42
58	Autosomal dominant mendelian susceptibility to mycobacterial diseases due to partial ifngammar2 deficiency	Enrichment	IFNGR2	2.42
59	Neurocutaneous melanocytosis	Enrichment	NRAS	2.42
60	Bladder cancer	Enrichment	HRAS, KRAS	2.28
61	Non-immune hydrops fetalis	Enrichment	HRAS, KRAS	2.22
62	Scoliosis, isolated 1	Enrichment	MAPK7	2.12
63	Costello syndrome	Enrichment	HRAS	2.12
64	Hypercalcemia, infantile, 1	Enrichment	CYP24A1	2.12
65	Encephalocraniocutaneous lipomatosis	Enrichment	KRAS	2.12
66	Immunodeficiency 45	Enrichment	IFNAR2	2.12
67	Yao syndrome	Enrichment	NOD2	2.12
68	Immunodeficiency, common variable, 12, with autoimmunity	Enrichment	NFKB1	2.12
69	Immunodeficiency, common variable, 10	Enrichment	NFKB2	2.12
70	Immunodeficiency 31c	Enrichment	STAT1	2.12
71	Immunodeficiency 127	Enrichment	TNF	2.12
72	Intermittent hydrarthrosis	Enrichment	TNFRSF1A	2.12
73	Autosomal recessive infantile hypercalcemia	Enrichment	CYP24A1	2.12
74	Crohn's disease	Enrichment	NOD2	2.12
75	Common variable immunodeficiency 12	Enrichment	NFKB1	2.12
76	Wooly hair nevus	Enrichment	HRAS	2.12
77	Systemic lupus erythematosus	Enrichment	ETS1, TNF	2.03
78	Leukemia, acute myeloid	Enrichment	KRAS, NRAS	2.01
79	Jacobsen syndrome	Enrichment	ETS1	1.95
80	Tuberous sclerosis 1	Enrichment	IFNG	1.95
81	Vitamin d hydroxylation-deficient rickets, type 1a	Enrichment	CYP27B1	1.95
82	Langerhans cell histiocytosis	Enrichment	NRAS	1.95
83	Psoriatic arthritis	Enrichment	TNF	1.95
84	Hepatitis c virus	Enrichment	IFNG	1.95
85	Tuberous sclerosis 2	Enrichment	IFNG	1.95
86	Immunodeficiency 28	Enrichment	IFNGR2	1.95
87	Migraine without aura	Enrichment	TNF	1.95
88	Immunodeficiency 44	Enrichment	IFNAR2	1.95
89	Spermatocytoma	Enrichment	HRAS	1.95
90	Kaposi sarcoma	Enrichment	IL6	1.83
91	Cardiofaciocutaneous syndrome 1	Enrichment	KRAS	1.83
92	Diffuse gastric and lobular breast cancer syndrome	Enrichment	KRAS	1.83
93	Chromosome 22q11.2 deletion syndrome, distal	Enrichment	MAPK1	1.83
94	Immunodeficiency, common variable, 1	Enrichment	NFKB2	1.83
95	Cardiofaciocutaneous syndrome	Enrichment	KRAS	1.83
96	Lung sarcomatoid carcinoma	Enrichment	KRAS	1.83
97	Hereditary ataxia	Enrichment	PRKCG	1.83
98	Pilocytic astrocytoma	Enrichment	KRAS	1.83
99	Epidermolytic nevus	Enrichment	HRAS	1.83
100	Cerebral malaria	Enrichment	TNF	1.83
101	Systemic-onset juvenile idiopathic arthritis	Enrichment	IL6	1.83
102	Vitamin d-dependent rickets, type 2a	Enrichment	VDR	1.73
103	Rheumatoid arthritis, systemic juvenile	Enrichment	IL6	1.73
104	Vascular dementia	Enrichment	TNF	1.73
105	Diffuse cutaneous systemic sclerosis	Enrichment	CAV1	1.73
106	Idiopathic aplastic anemia	Enrichment	IFNG	1.73
107	Myeloma, multiple	Enrichment	KRAS, RXRA	1.73
108	Type 1 diabetes mellitus	Enrichment	IL6	1.65
109	Chronic mucocutaneous candidiasis	Enrichment	STAT1	1.65
110	Limited scleroderma	Enrichment	CAV1	1.65
111	Breast adenocarcinoma	Enrichment	KRAS	1.65
112	Lung squamous cell carcinoma	Enrichment	KRAS	1.65
113	Capillary malformation-arteriovenous malformation 1	Enrichment	KRAS	1.58
114	Gallbladder cancer	Enrichment	KRAS	1.58
115	Pilomyxoid astrocytoma	Enrichment	KRAS	1.58
116	Breast cancer	Enrichment	JUN, KRAS	1.49
117	Charge syndrome	Enrichment	TNFRSF1A	1.48
118	Arteriovenous malformation	Enrichment	HRAS	1.48
119	Myopathy, x-linked, with excessive autophagy	Enrichment	HRAS	1.43
120	Ciliary dyskinesia, primary, 3	Enrichment	NFKB1	1.43
121	Aplastic anemia	Enrichment	IFNG	1.43
122	Asthma	Enrichment	TNF	1.39
123	Heritable pulmonary arterial hypertension	Enrichment	CAV1	1.39
124	Specific learning disability	Enrichment	MAPK1	1.39
125	Lip and oral cavity carcinoma	Enrichment	HRAS	1.35
126	Pulmonary disease, chronic obstructive	Enrichment	VDR	1.32
127	Alzheimer's disease	Enrichment	TNF	1.32
128	Chromosome 1p36 deletion syndrome	Enrichment	PRKCZ	1.32
129	Protein-deficiency anemia	Enrichment	NRAS	1.32
130	Lung cancer susceptibility 3	Enrichment	KRAS	1.29
131	Lynch syndrome	Enrichment	KRAS	1.26
132	Rhabdomyosarcoma	Enrichment	HRAS	1.23
133	Heart, malformation of	Enrichment	MAPK1	1.18
134	Hepatocellular carcinoma	Enrichment	VDR	1.10
135	Multisystem inflammatory syndrome in children	Enrichment	IFNAR2	1.10
136	Malaria	Enrichment	TNF	1.08
137	Pancreatic cancer	Enrichment	KRAS	1.05
138	Hydrops fetalis, nonimmune	Enrichment	HRAS	1.03
139	Lung cancer	Enrichment	KRAS	0.94
140	Severe combined immunodeficiency	Enrichment	IKBKB	0.93
141	Type 2 diabetes mellitus	Enrichment	IL6	0.83
142	Gastric cancer	Enrichment	KRAS	0.82
143	Hereditary breast carcinoma	Enrichment	KRAS	0.82
144	Hereditary breast ovarian cancer syndrome	Enrichment	KRAS	0.73
145	Colorectal cancer	Enrichment	NRAS	0.55
146	Ovarian cancer	Enrichment	KRAS	0.50
147	Microcephaly	Enrichment	MAPK1	0.43

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Non-genomic actions of 1,25 dihydroxyvitamin D3

Pathway Network for Non-genomic actions of 1,25 dihydroxyvitamin D3

Member Pathways for Non-genomic actions of 1,25 dihydroxyvitamin D3

Pathways in the Non-genomic actions of 1,25 dihydroxyvitamin D3 SuperPath

Associated Genes for Non-genomic actions of 1,25 dihydroxyvitamin D3

Associated Disorders for Non-genomic actions of 1,25 dihydroxyvitamin D3

Disorders associated with Non-genomic actions of 1,25 dihydroxyvitamin D3 SuperPath

STRING Interaction Network for Non-genomic actions of 1,25 dihydroxyvitamin D3

Sources for Non-genomic actions of 1,25 dihydroxyvitamin D3