Nuclear receptors meta-pathway

No Pathway Network information available for Nuclear receptors meta-pathway

Pathways in the Nuclear receptors meta-pathway SuperPath

#	Name	Source	Genes
1	Nuclear receptors meta-pathway	WikiPathways	ABCB1 ABCB11 ABCB4 ABCC2 ABCC3 ABCC4 ABCC5 ABCG5 ABCG8 ABHD2 ACAA1 ACADM ACKR3 ACOX1 ADGRF4 ADH7 AGER AHR AHRR AIP AKAP13 ALAS1 ALDH3A1 ALOX5AP AMIGO2 ANGPTL4 ANKRD1 APOA1 APOA2 APOA5 APOC3 ARL5B ARNT B3GNT5 BAAT BAX BHLHE40 BIRC2 BIRC3 BLVRB CAP2 CAVIN2 CBR1 CBR3 CCL2 CCL20 CCND1 CDC37 CDC42EP3 CDK1 CDK4 CDKN1B CDKN1C CES1 CES2 CES3 CES4A CES5A CPEB4 CPT1A CPT2 CUL1 CYP1A1 CYP1A2 CYP1B1 CYP2A6 CYP2B6 CYP2C19 CYP2C9 CYP3A4 CYP3A5 CYP3A7 CYP4A11 CYP4F12 CYP7A1 CYP8B1 DBI DNAJB1 DNAJC15 DNAJC7 DNER EDN2 EGFR EGR1 EHHADH ENC1 EP300 EPB41L4B EPHA2 EPHA3 ESR1 ETNK2 FABP1 FASN FGD4 FGF13 FGF19 FGFBP1 FKBP5 FOXO1 FTH1 FTL G6PD GADD45B GCC1 GCLC GCLM GGT1 GPAM GPR153 GPX2 GPX3 GSR GSTA1 GSTA2 GSTA3 GSTA4 GSTA5 GSTM1 GSTM2 GSTM3 GSTM4 GSTM5 GSTP1 GSTT2 HBEGF HES1 HGF HMOX1 HSP90AA1 HSP90AB1 HSPA1A IFNG IGFBP1 IL11 IL12A IL12B IL17B IL1B IL2 IP6K3 IRS2 JUN JUNB JUND KAT2B KEAP1 KLK15 KTN1 LRRC8A MAFF MAFG ME1 MFGE8 MGST1 MGST2 MGST3 MT1IP MYC MYOF NAV3 NCOA1 NCOA2 NCOA3 NCOA6 NFE2L2 NFKB2 NQO1 NR0B2 NR1H3 NR1H4 NR1I2 NR1I3 NR3C1 NRG1 NRIP1 PCK1 PDE4B PDGFB PDK4 PGD PLK2 PLTP PMP2 POLK POU5F1 PPARA PPARD PPARGC1A PPP1R14C PRDX1 PRDX6 PRRG4 PSMC5 PTGES3 PTGR1 PTGS2 PTPA RGS2 RXRA S100P SCD SCNN1A SCP2 SEC14L1 SERPINA1 SERPINB2 SERPINB9 SERTAD2 SLC10A1 SLC19A2 SLC26A2 SLC27A1 SLC27A5 SLC2A1 SLC2A10 SLC2A11 SLC2A12 SLC2A13 SLC2A14 SLC2A2 SLC2A3 SLC2A4 SLC2A5 SLC2A6 SLC2A7 SLC2A8 SLC2A9 SLC39A1 SLC39A10 SLC39A11 SLC39A12 SLC39A13 SLC39A14 SLC39A2 SLC39A3 SLC39A4 SLC39A5 SLC39A6 SLC39A7 SLC39A8 SLC39A9 SLC5A1 SLC5A10 SLC5A11 SLC5A12 SLC5A2 SLC5A3 SLC5A4 SLC5A5 SLC5A6 SLC5A7 SLC5A8 SLC5A9 SLC6A1 SLC6A11 SLC6A13 SLC6A14 SLC6A15 SLC6A16 SLC6A17 SLC6A18 SLC6A19 SLC6A2 SLC6A20 SLC6A3 SLC6A4 SLC6A5 SLC6A6 SLC6A7 SLC6A8 SLC6A9 SLC7A11 SLC7A5 SLCO1B1 SLCO2B1 SMARCA1 SMC1A SNAI2 SOD3 SP1 SPINK13 SPRY1 SQSTM1 SRC SREBF1 SRGN SRPX2 SRXN1 STAT3 STOM SULT1A1 SULT2A1 TGFA TGFB1 TGFB2 TGFBR2 TGFBR3 THBD TNF TNFAIP3 TNS4 TSC22D3 TXN TXNRD1 TXNRD3 UGT1A1 UGT1A4 UGT1A6 UGT1A7 UGT1A9 UGT2B4 UGT2B7 VDR ZIC2 (see all 315) (see less)
2	NRF2 pathway	WikiPathways	ABCC2 ABCC3 ABCC4 ABCC5 ADH7 AGER ALDH3A1 BLVRB CBR1 CBR3 CES1 CES2 CES3 CES4A CES5A CYP2A6 CYP4A11 DNAJB1 EGR1 EPHA2 EPHA3 FGF13 FTH1 FTL G6PD GCLC GCLM GGT1 GPX2 GPX3 GSR GSTA1 GSTA2 GSTA3 GSTA4 GSTA5 GSTM1 GSTM2 GSTM3 GSTM4 GSTM5 GSTP1 GSTT2 HBEGF HGF HMOX1 HSP90AA1 HSP90AB1 HSPA1A KEAP1 MAFF MAFG ME1 MGST2 MGST3 NFE2L2 NQO1 NRG1 PDGFB PGD PPARD PRDX1 PRDX6 PTGR1 RXRA SERPINA1 SLC2A1 SLC2A10 SLC2A11 SLC2A12 SLC2A13 SLC2A14 SLC2A2 SLC2A3 SLC2A4 SLC2A5 SLC2A6 SLC2A7 SLC2A8 SLC2A9 SLC39A1 SLC39A10 SLC39A11 SLC39A12 SLC39A13 SLC39A14 SLC39A2 SLC39A3 SLC39A4 SLC39A5 SLC39A6 SLC39A7 SLC39A8 SLC39A9 SLC5A1 SLC5A10 SLC5A11 SLC5A12 SLC5A2 SLC5A3 SLC5A4 SLC5A5 SLC5A6 SLC5A7 SLC5A8 SLC5A9 SLC6A1 SLC6A11 SLC6A13 SLC6A14 SLC6A15 SLC6A16 SLC6A17 SLC6A18 SLC6A19 SLC6A2 SLC6A20 SLC6A3 SLC6A4 SLC6A5 SLC6A6 SLC6A7 SLC6A8 SLC6A9 SLC7A11 SOD3 SQSTM1 SRXN1 TGFA TGFB1 TGFB2 TGFBR2 TXN TXNRD1 TXNRD3 UGT1A1 UGT1A4 UGT1A6 UGT1A7 UGT1A9 UGT2B7 (see all 141) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	UGT1A7	UDP Glucuronosyltransferase Family 1 Member A7	Protein Coding	2
2	SLC2A8	Solute Carrier Family 2 Member 8	Protein Coding	2
3	SLC2A12	Solute Carrier Family 2 Member 12	Protein Coding	2
4	KEAP1	Kelch Like ECH Associated Protein 1	Protein Coding	2
5	PRDX6	Peroxiredoxin 6	Protein Coding	2
6	SLC6A5	Solute Carrier Family 6 Member 5	Protein Coding	2
7	SLC39A13	Solute Carrier Family 39 Member 13	Protein Coding	2
8	SQSTM1	Sequestosome 1	Protein Coding	2
9	CES2	Carboxylesterase 2	Protein Coding	2
10	CBR3	Carbonyl Reductase 3	Protein Coding	2
11	CBR1	Carbonyl Reductase 1	Protein Coding	2
12	ABCC3	ATP Binding Cassette Subfamily C Member 3	Protein Coding	2
13	SLC2A10	Solute Carrier Family 2 Member 10	Protein Coding	2
14	UGT2B7	UDP Glucuronosyltransferase Family 2 Member B7	Protein Coding	2
15	TXNRD1	Thioredoxin Reductase 1	Protein Coding	2
16	TXN	Thioredoxin	Protein Coding	2
17	TGFBR2	Transforming Growth Factor Beta Receptor 2	Protein Coding	2
18	TGFB2	Transforming Growth Factor Beta 2	Protein Coding	2
19	TGFB1	Transforming Growth Factor Beta 1	Protein Coding	2
20	TGFA	Transforming Growth Factor Alpha	Protein Coding	2
21	SOD3	Superoxide Dismutase 3	Protein Coding	2
22	SLC6A11	Solute Carrier Family 6 Member 11	Protein Coding	2
23	SLC6A9	Solute Carrier Family 6 Member 9	Protein Coding	2
24	SLC6A8	Solute Carrier Family 6 Member 8	Protein Coding	2
25	SLC6A6	Solute Carrier Family 6 Member 6	Protein Coding	2
26	SLC6A4	Solute Carrier Family 6 Member 4	Protein Coding	2
27	SLC6A3	Solute Carrier Family 6 Member 3	Protein Coding	2
28	SLC6A2	Solute Carrier Family 6 Member 2	Protein Coding	2
29	SLC6A1	Solute Carrier Family 6 Member 1	Protein Coding	2
30	SLC5A5	Solute Carrier Family 5 Member 5	Protein Coding	2
31	SLC5A3	Solute Carrier Family 5 Member 3	Protein Coding	2
32	SLC5A2	Solute Carrier Family 5 Member 2	Protein Coding	2
33	SLC5A1	Solute Carrier Family 5 Member 1	Protein Coding	2
34	SLC2A5	Solute Carrier Family 2 Member 5	Protein Coding	2
35	SLC2A4	Solute Carrier Family 2 Member 4	Protein Coding	2
36	SLC2A3	Solute Carrier Family 2 Member 3	Protein Coding	2
37	SLC2A2	Solute Carrier Family 2 Member 2	Protein Coding	2
38	SLC2A1	Solute Carrier Family 2 Member 1	Protein Coding	2
39	BLVRB	Biliverdin Reductase B	Protein Coding	2
40	SLC39A8	Solute Carrier Family 39 Member 8	Protein Coding	2
41	RXRA	Retinoid X Receptor Alpha	Protein Coding	2
42	SLC5A7	Solute Carrier Family 5 Member 7	Protein Coding	2
43	SLC39A10	Solute Carrier Family 39 Member 10	Protein Coding	2
44	SLC2A9	Solute Carrier Family 2 Member 9	Protein Coding	2
45	SLC39A4	Solute Carrier Family 39 Member 4	Protein Coding	2
46	SLC6A20	Solute Carrier Family 6 Member 20	Protein Coding	2
47	PPARD	Peroxisome Proliferator Activated Receptor Delta	Protein Coding	2
48	UGT1A1	UDP Glucuronosyltransferase Family 1 Member A1	Protein Coding	2
49	UGT1A4	UDP Glucuronosyltransferase Family 1 Member A4	Protein Coding	2
50	UGT1A9	UDP Glucuronosyltransferase Family 1 Member A9	Protein Coding	2
51	UGT1A6	UDP Glucuronosyltransferase Family 1 Member A6	Protein Coding	2
52	SERPINA1	Serpin Family A Member 1	Protein Coding	2
53	PGD	Phosphogluconate Dehydrogenase	Protein Coding	2
54	PDGFB	Platelet Derived Growth Factor Subunit B	Protein Coding	2
55	PRDX1	Peroxiredoxin 1	Protein Coding	2
56	NFE2L2	NFE2 Like BZIP Transcription Factor 2	Protein Coding	2
57	ME1	Malic Enzyme 1	Protein Coding	2
58	MAFG	MAF BZIP Transcription Factor G	Protein Coding	2
59	SLC6A17	Solute Carrier Family 6 Member 17	Protein Coding	2
60	SLC6A18	Solute Carrier Family 6 Member 18	Protein Coding	2
61	SLC6A19	Solute Carrier Family 6 Member 19	Protein Coding	2
62	HSP90AB1	Heat Shock Protein 90 Alpha Family Class B Member 1	Protein Coding	2
63	HSP90AA1	Heat Shock Protein 90 Alpha Family Class A Member 1	Protein Coding	2
64	HSPA1A	Heat Shock Protein Family A (Hsp70) Member 1A	Protein Coding	2
65	HMOX1	Heme Oxygenase 1	Protein Coding	2
66	NRG1	Neuregulin 1	Protein Coding	2
67	HGF	Hepatocyte Growth Factor	Protein Coding	2
68	GSTT2	Glutathione S-Transferase Theta 2 (Gene/Pseudogene)	Protein Coding	2
69	GSTP1	Glutathione S-Transferase Pi 1	Protein Coding	2
70	GSTM5	Glutathione S-Transferase Mu 5	Protein Coding	2
71	GSTM4	Glutathione S-Transferase Mu 4	Protein Coding	2
72	GSTM3	Glutathione S-Transferase Mu 3	Protein Coding	2
73	GSTM2	Glutathione S-Transferase Mu 2	Protein Coding	2
74	GSTM1	Glutathione S-Transferase Mu 1	Protein Coding	2
75	GSTA4	Glutathione S-Transferase Alpha 4	Protein Coding	2
76	GSTA3	Glutathione S-Transferase Alpha 3	Protein Coding	2
77	GSTA2	Glutathione S-Transferase Alpha 2	Protein Coding	2
78	GSTA1	Glutathione S-Transferase Alpha 1	Protein Coding	2
79	GSR	Glutathione-Disulfide Reductase	Protein Coding	2
80	GPX3	Glutathione Peroxidase 3	Protein Coding	2
81	GPX2	Glutathione Peroxidase 2	Protein Coding	2
82	SLC39A5	Solute Carrier Family 39 Member 5	Protein Coding	2
83	GCLM	Glutamate-Cysteine Ligase Modifier Subunit	Protein Coding	2
84	GCLC	Glutamate-Cysteine Ligase Catalytic Subunit	Protein Coding	2
85	SLC39A1	Solute Carrier Family 39 Member 1	Protein Coding	2
86	GGT1	Gamma-Glutamyltransferase 1	Protein Coding	2
87	SLC39A6	Solute Carrier Family 39 Member 6	Protein Coding	2
88	G6PD	Glucose-6-Phosphate Dehydrogenase	Protein Coding	2
89	FTL	Ferritin Light Chain	Protein Coding	2
90	FTH1	Ferritin Heavy Chain 1	Protein Coding	2
91	MAFF	MAF BZIP Transcription Factor F	Protein Coding	2
92	SLC7A11	Solute Carrier Family 7 Member 11	Protein Coding	2
93	SLC39A14	Solute Carrier Family 39 Member 14	Protein Coding	2
94	CES3	Carboxylesterase 3	Protein Coding	2
95	PTGR1	Prostaglandin Reductase 1	Protein Coding	2
96	FGF13	Fibroblast Growth Factor 13	Protein Coding	2
97	GSTA5	Glutathione S-Transferase Alpha 5	Protein Coding	2
98	SLC39A12	Solute Carrier Family 39 Member 12	Protein Coding	2
99	ALDH3A1	Aldehyde Dehydrogenase 3 Family Member A1	Protein Coding	2
100	EPHA3	EPH Receptor A3	Protein Coding	2
101	EPHA2	EPH Receptor A2	Protein Coding	2
102	EGR1	Early Growth Response 1	Protein Coding	2
103	HBEGF	Heparin Binding EGF Like Growth Factor	Protein Coding	2
104	AGER	Advanced Glycosylation End-Product Specific Receptor	Protein Coding	2
105	NQO1	NAD(P)H Quinone Dehydrogenase 1	Protein Coding	2
106	SLC5A8	Solute Carrier Family 5 Member 8	Protein Coding	2
107	CYP4A11	Cytochrome P450 Family 4 Subfamily A Member 11	Protein Coding	2
108	CYP2A6	Cytochrome P450 Family 2 Subfamily A Member 6	Protein Coding	2
109	SLC2A14	Solute Carrier Family 2 Member 14	Protein Coding	2
110	ADH7	Alcohol Dehydrogenase 7 (Class IV), Mu Or Sigma Polypeptide	Protein Coding	2
111	ABCC2	ATP Binding Cassette Subfamily C Member 2	Protein Coding	2
112	SLC2A13	Solute Carrier Family 2 Member 13	Protein Coding	2
113	TXNRD3	Thioredoxin Reductase 3	Protein Coding	2
114	SLC6A14	Solute Carrier Family 6 Member 14	Protein Coding	2
115	CES1	Carboxylesterase 1	Protein Coding	2
116	ABCC4	ATP Binding Cassette Subfamily C Member 4 (PEL Blood Group)	Protein Coding	2
117	ABCC5	ATP Binding Cassette Subfamily C Member 5	Protein Coding	2
118	SLC5A12	Solute Carrier Family 5 Member 12	Protein Coding	2
119	SLC2A7	Solute Carrier Family 2 Member 7	Protein Coding	2
120	SLC5A6	Solute Carrier Family 5 Member 6	Protein Coding	2
121	SRXN1	Sulfiredoxin 1	Protein Coding	2
122	SLC5A10	Solute Carrier Family 5 Member 10	Protein Coding	2
123	SLC5A11	Solute Carrier Family 5 Member 11	Protein Coding	2
124	SLC2A6	Solute Carrier Family 2 Member 6	Protein Coding	2
125	SLC39A7	Solute Carrier Family 39 Member 7	Protein Coding	2
126	SLC2A11	Solute Carrier Family 2 Member 11	Protein Coding	2
127	SLC6A13	Solute Carrier Family 6 Member 13	Protein Coding	2
128	SLC6A7	Solute Carrier Family 6 Member 7	Protein Coding	2
129	SLC5A4	Solute Carrier Family 5 Member 4	Protein Coding	2
130	SLC39A9	Solute Carrier Family 39 Member 9	Protein Coding	2
131	SLC6A15	Solute Carrier Family 6 Member 15	Protein Coding	2
132	MGST3	Microsomal Glutathione S-Transferase 3	Protein Coding	2
133	MGST2	Microsomal Glutathione S-Transferase 2	Protein Coding	2
134	DNAJB1	DnaJ Heat Shock Protein Family (Hsp40) Member B1	Protein Coding	2
135	SLC39A2	Solute Carrier Family 39 Member 2	Protein Coding	2
136	SLC39A3	Solute Carrier Family 39 Member 3	Protein Coding	2
137	SLC6A16	Solute Carrier Family 6 Member 16	Protein Coding	2
138	CES4A	Carboxylesterase 4A	Protein Coding	2
139	CES5A	Carboxylesterase 5A	Protein Coding	2
140	SLC39A11	Solute Carrier Family 39 Member 11	Protein Coding	2
141	SLC5A9	Solute Carrier Family 5 Member 9	Protein Coding	2
142	B3GNT5	UDP-GlcNAc:BetaGal Beta-1,3-N-Acetylglucosaminyltransferase 5	Protein Coding	1
143	BAAT	Bile Acid-CoA:Amino Acid N-Acyltransferase	Protein Coding	1
144	ETNK2	Ethanolamine Kinase 2	Protein Coding	1
145	ACAA1	Acetyl-CoA Acyltransferase 1	Protein Coding	1
146	SLC27A5	Solute Carrier Family 27 Member 5	Protein Coding	1
147	NR1H4	Nuclear Receptor Subfamily 1 Group H Member 4	Protein Coding	1
148	NR1I3	Nuclear Receptor Subfamily 1 Group I Member 3	Protein Coding	1
149	FGF19	Fibroblast Growth Factor 19	Protein Coding	1
150	CDK1	Cyclin Dependent Kinase 1	Protein Coding	1
151	AIP	AHR Interacting HSP90 Co-Chaperone	Protein Coding	1
152	NAV3	Neuron Navigator 3	Protein Coding	1
153	NR1I2	Nuclear Receptor Subfamily 1 Group I Member 2	Protein Coding	1
154	IRS2	Insulin Receptor Substrate 2	Protein Coding	1
155	NCOA1	Nuclear Receptor Coactivator 1	Protein Coding	1
156	ABCB11	ATP Binding Cassette Subfamily B Member 11	Protein Coding	1
157	BHLHE40	Basic Helix-Loop-Helix Family Member E40	Protein Coding	1
158	ENC1	Ectodermal-Neural Cortex 1	Protein Coding	1
159	CUL1	Cullin 1	Protein Coding	1
160	CAVIN2	Caveolae Associated Protein 2	Protein Coding	1
161	NR0B2	Nuclear Receptor Subfamily 0 Group B Member 2	Protein Coding	1
162	SMC1A	Structural Maintenance Of Chromosomes 1A	Protein Coding	1
163	NRIP1	Nuclear Receptor Interacting Protein 1	Protein Coding	1
164	NCOA3	Nuclear Receptor Coactivator 3	Protein Coding	1
165	SLC7A5	Solute Carrier Family 7 Member 5	Protein Coding	1
166	GCC1	GRIP And Coiled-Coil Domain Containing 1	Protein Coding	1
167	ZIC2	Zic Family Zinc Finger 2	Protein Coding	1
168	VDR	Vitamin D Receptor	Protein Coding	1
169	UGT2B4	UDP Glucuronosyltransferase Family 2 Member B4	Protein Coding	1
170	DNAJC7	DnaJ Heat Shock Protein Family (Hsp40) Member C7	Protein Coding	1
171	TNFAIP3	TNF Alpha Induced Protein 3	Protein Coding	1
172	TNF	Tumor Necrosis Factor	Protein Coding	1
173	THBD	Thrombomodulin	Protein Coding	1
174	SULT2A1	Sulfotransferase Family 2A Member 1	Protein Coding	1
175	SULT1A1	Sulfotransferase Family 1A Member 1	Protein Coding	1
176	STAT3	Signal Transducer And Activator Of Transcription 3	Protein Coding	1
177	SREBF1	Sterol Regulatory Element Binding Transcription Factor 1	Protein Coding	1
178	SRC	SRC Proto-Oncogene, Non-Receptor Tyrosine Kinase	Protein Coding	1
179	SP1	Sp1 Transcription Factor	Protein Coding	1
180	CYP4F12	Cytochrome P450 Family 4 Subfamily F Member 12	Protein Coding	1
181	SMARCA1	SNF2 Related Chromatin Remodeling ATPase 1	Protein Coding	1
182	SNAI2	Snail Family Transcriptional Repressor 2	Protein Coding	1
183	SLC10A1	Solute Carrier Family 10 Member 1	Protein Coding	1
184	ABCG8	ATP Binding Cassette Subfamily G Member 8	Protein Coding	1
185	ABCG5	ATP Binding Cassette Subfamily G Member 5	Protein Coding	1
186	CCL20	C-C Motif Chemokine Ligand 20	Protein Coding	1
187	CCL2	C-C Motif Chemokine Ligand 2	Protein Coding	1
188	SCP2	Sterol Carrier Protein 2	Protein Coding	1
189	SCNN1A	Sodium Channel Epithelial 1 Subunit Alpha	Protein Coding	1
190	SCD	Stearoyl-CoA Desaturase	Protein Coding	1
191	S100P	S100 Calcium Binding Protein P	Protein Coding	1
192	RGS2	Regulator Of G Protein Signaling 2	Protein Coding	1
193	CCND1	Cyclin D1	Protein Coding	1
194	BAX	BCL2 Associated X, Apoptosis Regulator	Protein Coding	1
195	GPAM	Glycerol-3-Phosphate Acyltransferase, Mitochondrial	Protein Coding	1
196	PTGS2	Prostaglandin-Endoperoxide Synthase 2	Protein Coding	1
197	PSMC5	Proteasome 26S Subunit, ATPase 5	Protein Coding	1
198	ACKR3	Atypical Chemokine Receptor 3	Protein Coding	1
199	LRRC8A	Leucine Rich Repeat Containing 8 VRAC Subunit A	Protein Coding	1
200	SRGN	Serglycin	Protein Coding	1
201	PTPA	Protein Phosphatase 2 Phosphatase Activator	Protein Coding	1
202	PPARA	Peroxisome Proliferator Activated Receptor Alpha	Protein Coding	1
203	POU5F1	POU Class 5 Homeobox 1	Protein Coding	1
204	PLTP	Phospholipid Transfer Protein	Protein Coding	1
205	SERPINB9	Serpin Family B Member 9	Protein Coding	1
206	ABCB4	ATP Binding Cassette Subfamily B Member 4	Protein Coding	1
207	ABCB1	ATP Binding Cassette Subfamily B Member 1	Protein Coding	1
208	PDK4	Pyruvate Dehydrogenase Kinase 4	Protein Coding	1
209	POLK	DNA Polymerase Kappa	Protein Coding	1
210	PDE4B	Phosphodiesterase 4B	Protein Coding	1
211	ANGPTL4	Angiopoietin Like 4	Protein Coding	1
212	PCK1	Phosphoenolpyruvate Carboxykinase 1	Protein Coding	1
213	ACOX1	Acyl-CoA Oxidase 1	Protein Coding	1
214	SERPINB2	Serpin Family B Member 2	Protein Coding	1
215	NFKB2	Nuclear Factor Kappa B Subunit 2	Protein Coding	1
216	GADD45B	Growth Arrest And DNA Damage Inducible Beta	Protein Coding	1
217	MYC	MYC Proto-Oncogene, BHLH Transcription Factor	Protein Coding	1
218	MGST1	Microsomal Glutathione S-Transferase 1	Protein Coding	1
219	MFGE8	Milk Fat Globule EGF And Factor V/VIII Domain Containing	Protein Coding	1
220	ARNT	Aryl Hydrocarbon Receptor Nuclear Translocator	Protein Coding	1
221	KTN1	Kinectin 1	Protein Coding	1
222	GPR153	G Protein-Coupled Receptor 153	Protein Coding	1
223	JUND	JunD Proto-Oncogene, AP-1 Transcription Factor Subunit	Protein Coding	1
224	JUNB	JunB Proto-Oncogene, AP-1 Transcription Factor Subunit	Protein Coding	1
225	JUN	Jun Proto-Oncogene, AP-1 Transcription Factor Subunit	Protein Coding	1
226	IL12B	Interleukin 12B	Protein Coding	1
227	IL12A	Interleukin 12A	Protein Coding	1
228	IL11	Interleukin 11	Protein Coding	1
229	IL2	Interleukin 2	Protein Coding	1
230	IL1B	Interleukin 1 Beta	Protein Coding	1
231	IGFBP1	Insulin Like Growth Factor Binding Protein 1	Protein Coding	1
232	IFNG	Interferon Gamma	Protein Coding	1
233	APOC3	Apolipoprotein C3	Protein Coding	1
234	ACADM	Acyl-CoA Dehydrogenase Medium Chain	Protein Coding	1
235	APOA2	Apolipoprotein A2	Protein Coding	1
236	APOA1	Apolipoprotein A1	Protein Coding	1
237	BIRC3	Baculoviral IAP Repeat Containing 3	Protein Coding	1
238	BIRC2	Baculoviral IAP Repeat Containing 2	Protein Coding	1
239	HES1	Hes Family BHLH Transcription Factor 1	Protein Coding	1
240	DNAJC15	DnaJ Heat Shock Protein Family (Hsp40) Member C15	Protein Coding	1
241	NR3C1	Nuclear Receptor Subfamily 3 Group C Member 1	Protein Coding	1
242	SRPX2	Sushi Repeat Containing Protein X-Linked 2	Protein Coding	1
243	ANKRD1	Ankyrin Repeat Domain 1	Protein Coding	1
244	ALOX5AP	Arachidonate 5-Lipoxygenase Activating Protein	Protein Coding	1
245	FOXO1	Forkhead Box O1	Protein Coding	1
246	NCOA6	Nuclear Receptor Coactivator 6	Protein Coding	1
247	FKBP5	FKBP Prolyl Isomerase 5	Protein Coding	1
248	ADGRF4	Adhesion G Protein-Coupled Receptor F4	Protein Coding	1
249	ARL5B	ARF Like GTPase 5B	Protein Coding	1
250	FASN	Fatty Acid Synthase	Protein Coding	1
251	FABP1	Fatty Acid Binding Protein 1	Protein Coding	1
252	ALAS1	5''-Aminolevulinate Synthase 1	Protein Coding	1
253	ESR1	Estrogen Receptor 1	Protein Coding	1
254	EP300	EP300 Lysine Acetyltransferase	Protein Coding	1
255	EHHADH	Enoyl-CoA Hydratase And 3-Hydroxyacyl CoA Dehydrogenase	Protein Coding	1
256	AHR	Aryl Hydrocarbon Receptor	Protein Coding	1
257	EGFR	Epidermal Growth Factor Receptor	Protein Coding	1
258	EDN2	Endothelin 2	Protein Coding	1
259	SLC26A2	Solute Carrier Family 26 Member 2	Protein Coding	1
260	TSC22D3	TSC22 Domain Family Member 3	Protein Coding	1
261	DBI	Diazepam Binding Inhibitor, Acyl-CoA Binding Protein	Protein Coding	1
262	CYP8B1	Cytochrome P450 Family 8 Subfamily B Member 1	Protein Coding	1
263	CYP7A1	Cytochrome P450 Family 7 Subfamily A Member 1	Protein Coding	1
264	CYP3A5	Cytochrome P450 Family 3 Subfamily A Member 5	Protein Coding	1
265	CYP3A4	Cytochrome P450 Family 3 Subfamily A Member 4	Protein Coding	1
266	CYP2C9	Cytochrome P450 Family 2 Subfamily C Member 9	Protein Coding	1
267	CYP2C19	Cytochrome P450 Family 2 Subfamily C Member 19	Protein Coding	1
268	CYP2B6	Cytochrome P450 Family 2 Subfamily B Member 6	Protein Coding	1
269	CYP3A7	Cytochrome P450 Family 3 Subfamily A Member 7	Protein Coding	1
270	CYP1B1	Cytochrome P450 Family 1 Subfamily B Member 1	Protein Coding	1
271	CYP1A2	Cytochrome P450 Family 1 Subfamily A Member 2	Protein Coding	1
272	CYP1A1	Cytochrome P450 Family 1 Subfamily A Member 1	Protein Coding	1
273	CPT2	Carnitine Palmitoyltransferase 2	Protein Coding	1
274	CPT1A	Carnitine Palmitoyltransferase 1A	Protein Coding	1
275	FGD4	FYVE, RhoGEF And PH Domain Containing 4	Protein Coding	1
276	APOA5	Apolipoprotein A5	Protein Coding	1
277	AKAP13	A-Kinase Anchoring Protein 13	Protein Coding	1
278	PPARGC1A	PPARG Coactivator 1 Alpha	Protein Coding	1
279	PLK2	Polo Like Kinase 2	Protein Coding	1
280	PTGES3	Prostaglandin E Synthase 3	Protein Coding	1
281	SLCO1B1	Solute Carrier Organic Anion Transporter Family Member 1B1	Protein Coding	1
282	SLC19A2	Solute Carrier Family 19 Member 2	Protein Coding	1
283	NCOA2	Nuclear Receptor Coactivator 2	Protein Coding	1
284	CAP2	Cyclase Associated Actin Cytoskeleton Regulatory Protein 2	Protein Coding	1
285	CDKN1C	Cyclin Dependent Kinase Inhibitor 1C	Protein Coding	1
286	CDKN1B	Cyclin Dependent Kinase Inhibitor 1B	Protein Coding	1
287	CDK4	Cyclin Dependent Kinase 4	Protein Coding	1
288	NR1H3	Nuclear Receptor Subfamily 1 Group H Member 3	Protein Coding	1
289	SPINK13	Serine Peptidase Inhibitor Kazal Type 13	Protein Coding	1
290	FGFBP1	Fibroblast Growth Factor Binding Protein 1	Protein Coding	1
291	SERTAD2	SERTA Domain Containing 2	Protein Coding	1
292	DNER	Delta/Notch Like EGF Repeat Containing	Protein Coding	1
293	KAT2B	Lysine Acetyltransferase 2B	Protein Coding	1
294	TNS4	Tensin 4	Protein Coding	1
295	IP6K3	Inositol Hexakisphosphate Kinase 3	Protein Coding	1
296	SLCO2B1	Solute Carrier Organic Anion Transporter Family Member 2B1	Protein Coding	1
297	CDC37	Cell Division Cycle 37, HSP90 Cochaperone	Protein Coding	1
298	ABHD2	Abhydrolase Domain Containing 2, Acylglycerol Lipase	Protein Coding	1
299	CDC42EP3	CDC42 Effector Protein 3	Protein Coding	1
300	SPRY1	Sprouty RTK Signaling Antagonist 1	Protein Coding	1
301	PPP1R14C	Protein Phosphatase 1 Regulatory Inhibitor Subunit 14C	Protein Coding	1
302	CPEB4	Cytoplasmic Polyadenylation Element Binding Protein 4	Protein Coding	1
303	PRRG4	Proline Rich And Gla Domain 4	Protein Coding	1
304	TGFBR3	Transforming Growth Factor Beta Receptor 3	Protein Coding	1
305	MT1IP	Metallothionein 1I, Pseudogene	Pseudogene	1
306	SEC14L1	SEC14 Like Lipid Binding 1	Protein Coding	1
307	AHRR	Aryl Hydrocarbon Receptor Repressor	Protein Coding	1
308	KLK15	Kallikrein Related Peptidase 15	Protein Coding	1
309	EPB41L4B	Erythrocyte Membrane Protein Band 4.1 Like 4B	Protein Coding	1
310	PMP2	Peripheral Myelin Protein 2	Protein Coding	1
311	SLC27A1	Solute Carrier Family 27 Member 1	Protein Coding	1
312	AMIGO2	Adhesion Molecule With Ig Like Domain 2	Protein Coding	1
313	IL17B	Interleukin 17B	Protein Coding	1
314	MYOF	Myoferlin	Protein Coding	1
315	STOM	Stomatin	Protein Coding	1

Disorders associated with Nuclear receptors meta-pathway SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Crigler-najjar syndrome, type i	Enrichment	UGT1A1, UGT1A4, UGT1A6, UGT1A7, UGT1A9	7.56
2	Hyperbilirubinemia, transient familial neonatal	Enrichment	UGT1A1, UGT1A4, UGT1A6, UGT1A7, UGT1A9	7.56
3	Bilirubin, serum level of, quantitative trait locus 1	Enrichment	UGT1A1, UGT1A4, UGT1A6, UGT1A7, UGT1A9	7.56
4	Crigler-najjar syndrome, type ii	Enrichment	UGT1A1, UGT1A4, UGT1A6, UGT1A7, UGT1A9	7.56
5	Gilbert syndrome	Enrichment	UGT1A1, UGT1A4, UGT1A6, UGT1A7, UGT1A9	7.30
6	Bilirubin metabolic disorder	Enrichment	UGT1A1, UGT1A4, UGT1A6, UGT1A7, UGT1A9	7.30
7	Cystic fibrosis	Enrichment	GCLC, GSTM3, HMOX1, SERPINA1, SLC6A14, TGFB1	6.08
8	Iminoglycinuria	Enrichment	SLC6A18, SLC6A19, SLC6A20	5.36
9	Pulmonary disease, chronic obstructive	Enrichment	HMOX1, MGST1, MGST3, SERPINA1, VDR	5.14
10	Intrahepatic cholestasis of pregnancy	Enrichment	ABCB11, ABCB4, NR1H4	4.31
11	Cholestasis, progressive familial intrahepatic, 3	Enrichment	ABCB11, ABCB4	3.27
12	Gallbladder disease 4	Enrichment	ABCG5, ABCG8	3.27
13	Cholestasis, intrahepatic, of pregnancy 3	Enrichment	ABCB11, ABCB4	3.27
14	Intrahepatic cholestasis	Enrichment	ABCB11, ABCB4	3.27
15	Renal glucosuria	Enrichment	SLC5A1, SLC5A2	3.20
16	Tobacco addiction	Enrichment	CYP2A6, SLC6A3	3.20
17	Coronary heart disease 5	Enrichment	ABCG5, ABCG8, G6PD	3.03
18	Coumarin resistance	Enrichment	CYP2A6, CYP2C9	2.80
19	Sitosterolemia 1	Enrichment	ABCG5, ABCG8	2.80
20	Sitosterolemia	Enrichment	ABCG5, ABCG8	2.80
21	Migraine without aura	Enrichment	ESR1, TNF	2.80
22	Myoclonic-atonic epilepsy	Enrichment	SLC2A1, SLC6A1	2.43
23	Loeys-dietz syndrome	Enrichment	TGFB2, TGFBR2	2.43
24	Marfan syndrome	Enrichment	TGFB2, TGFBR2	2.34
25	Cholestasis, progressive familial intrahepatic, 1	Enrichment	ABCB4, NR1H4	2.12
26	Lipid metabolism disorder	Enrichment	ABCG5, ABCG8	2.12
27	Familial hypercholanemia	Enrichment	BAAT, SLC10A1	2.12
28	Neuronopathy, distal hereditary motor, autosomal dominant 7	Enrichment	SLC5A7	1.98
29	Paget disease of bone 3	Enrichment	SQSTM1	1.98
30	Hyperostosis cranialis interna	Enrichment	SLC39A14	1.98
31	Acrodermatitis enteropathica, zinc-deficiency type	Enrichment	SLC39A4	1.98
32	Thyroid dyshormonogenesis 1	Enrichment	SLC5A5	1.98
33	Ehlers-danlos syndrome, spondylodysplastic type, 3	Enrichment	SLC39A13	1.98
34	Deafness, autosomal recessive 39	Enrichment	HGF	1.98
35	Stomatin-deficient cryohydrocytosis with neurologic defects	Enrichment	SLC2A1	1.98
36	Neurodegeneration with brain iron accumulation 3	Enrichment	FTL	1.98
37	Basal ganglia calcification, idiopathic, 5	Enrichment	PDGFB	1.98
38	Hypotaurinemic retinal degeneration and cardiomyopathy	Enrichment	SLC6A6	1.98
39	Glutathionuria	Enrichment	GGT1	1.98
40	Anemia, congenital, nonspherocytic hemolytic, 7	Enrichment	GCLC	1.98
41	Anemia, congenital, nonspherocytic hemolytic, 10	Enrichment	GSR	1.98
42	Myopathy, distal, with rimmed vacuoles	Enrichment	SQSTM1	1.98
43	Frontotemporal dementia and/or amyotrophic lateral sclerosis 3	Enrichment	SQSTM1	1.98
44	Drug metabolism, altered, ces1-related	Enrichment	CES1	1.98
45	Agammaglobulinemia 9, autosomal recessive	Enrichment	SLC39A7	1.98
46	Intellectual developmental disorder, x-linked 110	Enrichment	FGF13	1.98
47	Cerebral creatine deficiency syndrome 1	Enrichment	SLC6A8	1.98
48	Immunodeficiency, developmental delay, and hypohomocysteinemia	Enrichment	NFE2L2	1.98
49	Acrodermatitis enteropathica	Enrichment	SLC39A4	1.98
50	Glucose/galactose malabsorption	Enrichment	SLC5A1	1.98
51	Developmental and epileptic encephalopathy 90	Enrichment	FGF13	1.98
52	Peripheral motor neuropathy, childhood-onset, biotin-responsive	Enrichment	SLC5A6	1.98
53	Camurati-engelmann disease 2	Enrichment	TGFB2	1.98
54	Parkinsonism-dystonia 1, infantile-onset	Enrichment	SLC6A3	1.98
55	Colorectal cancer, hereditary nonpolyposis, type 6	Enrichment	TGFBR2	1.98
56	Epilepsy, idiopathic generalized 12	Enrichment	SLC2A1	1.98
57	L-ferritin deficiency	Enrichment	FTL	1.98
58	Hyperekplexia 3	Enrichment	SLC6A5	1.98
59	Intellectual developmental disorder, autosomal recessive 48	Enrichment	SLC6A17	1.98
60	Myopia 24, autosomal dominant	Enrichment	SLC39A5	1.98
61	Alpha-1-antitrypsin deficiency	Enrichment	SERPINA1	1.98
62	Heme oxygenase 1 deficiency	Enrichment	HMOX1	1.98
63	Hypermanganesemia with dystonia 2	Enrichment	SLC39A14	1.98
64	Sodium-dependent multivitamin transporter deficiency	Enrichment	SLC5A6	1.98
65	Glycine encephalopathy with normal serum glycine	Enrichment	SLC6A9	1.98
66	Postural orthostatic tachycardia syndrome	Enrichment	SLC6A2	1.98
67	Classic dopamine transporter deficiency syndrome	Enrichment	SLC6A3	1.98
68	Hemorrhagic disease due to alpha-1-antitrypsin pittsburgh mutation	Enrichment	SERPINA1	1.98
69	Genetic hyperferritinemia without iron overload	Enrichment	FTL	1.98
70	Congenital nonspherocytic hemolytic anemia	Enrichment	G6PD	1.98
71	Epilepsy with myoclonic absences	Enrichment	SLC2A1	1.98
72	Parkinsonism-dystonia, infantile	Enrichment	SLC6A3	1.98
73	Hereditary cryohydrocytosis with reduced stomatin	Enrichment	SLC2A1	1.98
74	Letrozole toxicity	Enrichment	CYP2A6	1.98
75	Progressive familial intrahepatic cholestasis	Enrichment	ABCB11, ABCB4	1.98
76	Familial thoracic aortic aneurysm and aortic dissection	Enrichment	SLC2A10, TGFB2, TGFBR2	1.97
77	Homozygous familial hypercholesterolemia	Enrichment	ABCG5, ABCG8	1.86
78	Myocardial infarction	Enrichment	ESR1, GCLC, GCLM	1.86
79	Ehlers-danlos syndrome	Enrichment	TGFB2, TGFBR2	1.79
80	Hyperglycinuria	Enrichment	SLC6A19	1.68
81	Camurati-engelmann disease 1	Enrichment	TGFB1	1.68
82	Fanconi-bickel syndrome	Enrichment	SLC2A2	1.68
83	Vitreoretinochoroidopathy	Enrichment	FTH1	1.68
84	Dystonia 9	Enrichment	SLC2A1	1.68
85	Dermatofibrosarcoma protuberans	Enrichment	PDGFB	1.68
86	Loeys-dietz syndrome 2	Enrichment	TGFBR2	1.68
87	Welander distal myopathy	Enrichment	SQSTM1	1.68
88	Microvascular complications of diabetes 5	Enrichment	TGFBR2	1.68
89	Glut1 deficiency syndrome 1	Enrichment	SLC2A1	1.68
90	Obsessive-compulsive disorder	Enrichment	SLC6A4	1.68
91	Retinitis pigmentosa 50	Enrichment	FTH1	1.68
92	Hypouricemia, renal, 2	Enrichment	SLC2A9	1.68
93	Goiter, multinodular 1, with or without sertoli-leydig cell tumors	Enrichment	KEAP1	1.68
94	Hartnup disorder	Enrichment	SLC6A19	1.68
95	Hyperferritinemia with or without cataract	Enrichment	FTL	1.68
96	Neurodegeneration with ataxia, dystonia, and gaze palsy, childhood-onset	Enrichment	SQSTM1	1.68
97	Inflammatory bowel disease, immunodeficiency, and encephalopathy	Enrichment	TGFB1	1.68
98	Glucose transporter type 1 deficiency syndrome	Enrichment	SLC2A1	1.68
99	Kala-azar 2	Enrichment	GSTP1	1.68
100	Hemochromatosis, type 5	Enrichment	FTH1	1.68
101	Myasthenic syndrome, congenital, 20, presynaptic	Enrichment	SLC5A7	1.68
102	Camurati-engelmann disease	Enrichment	TGFB1	1.68
103	Fibrolamellar carcinoma	Enrichment	DNAJB1	1.68
104	Congenital hemolytic anemia	Enrichment	G6PD	1.68
105	Loeys-dietz syndrome 4	Enrichment	TGFB2	1.68
106	Familial renal hypouricemia	Enrichment	SLC2A9	1.68
107	Paget's disease of bone	Enrichment	SQSTM1	1.68
108	Slc6a1-related neurodevelopmental disorder	Enrichment	SLC6A1	1.68
109	Glucosephosphate dehydrogenase deficiency	Enrichment	G6PD	1.68
110	Distal hereditary motor neuropathy type 7	Enrichment	SLC5A7	1.68
111	Neurodegeneration with brain iron accumulation 9	Enrichment	FTH1	1.68
112	Spastic paraplegia-paget disease of bone syndrome	Enrichment	SQSTM1	1.68
113	Diastrophic dysplasia	Enrichment	SLC26A2	1.63
114	Developmental and epileptic encephalopathy 85 with or without midline brain defects	Enrichment	SMC1A	1.63
115	Phosphoenolpyruvate carboxykinase deficiency, cytosolic	Enrichment	PCK1	1.63
116	Drug metabolism, poor, cyp2c19-related	Enrichment	CYP2C19	1.63
117	Atelosteogenesis, type ii	Enrichment	SLC26A2	1.63
118	Melanoma, cutaneous malignant 3	Enrichment	CDK4	1.63
119	Hemolytic uremic syndrome, atypical 6	Enrichment	THBD	1.63
120	Colchicine resistance	Enrichment	ABCB1	1.63
121	Bronchiectasis with or without elevated sweat chloride 2	Enrichment	SCNN1A	1.63
122	Mucoepithelial dysplasia, hereditary	Enrichment	SREBF1	1.63
123	Epiphyseal dysplasia, multiple, 4	Enrichment	SLC26A2	1.63
124	Glucocorticoid resistance, generalized	Enrichment	NR3C1	1.63
125	Charcot-marie-tooth disease, demyelinating, type 4h	Enrichment	FGD4	1.63
126	Acyl-coa dehydrogenase, medium-chain, deficiency of	Enrichment	ACADM	1.63
127	Retinitis pigmentosa 85	Enrichment	AHR	1.63
128	Gallbladder disease 1	Enrichment	ABCB4	1.63
129	Neurodevelopmental disorder with poor or absent speech, dysmorphic facies, and behavioral abnormalities	Enrichment	NAV3	1.63
130	Fanconi renotubular syndrome 3	Enrichment	EHHADH	1.63
131	Immunodeficiency 69	Enrichment	IFNG	1.63
132	Peroxisomal acyl-coa oxidase deficiency	Enrichment	ACOX1	1.63
133	Rolandic epilepsy, impaired intellectual development, and speech dyspraxia, x-linked	Enrichment	SRPX2	1.63
134	Parkinson disease 25, autosomal recessive early-onset, with impaired intellectual development	Enrichment	PTPA	1.63
135	Cardiomyopathy, dilated, 2i	Enrichment	CAP2	1.63
136	Charcot-marie-tooth disease, demyelinating, type 1g	Enrichment	PMP2	1.63
137	Encephalopathy, acute transient	Enrichment	ABCB1	1.63
138	Mitchell syndrome	Enrichment	ACOX1	1.63
139	Liddle syndrome 3	Enrichment	SCNN1A	1.63
140	Foveal hypoplasia 3	Enrichment	AHR	1.63
141	Ifap syndrome 2	Enrichment	SREBF1	1.63
142	T-cell large granular lymphocyte leukemia	Enrichment	STAT3	1.63
143	Angioedema, hereditary, 7	Enrichment	MYOF	1.63
144	Achondrogenesis, type ib	Enrichment	SLC26A2	1.63
145	Familial apolipoprotein a5 deficiency	Enrichment	APOA5	1.63
146	Charcot-marie-tooth disease type 4h	Enrichment	FGD4	1.63
147	Hypercholanemia, familial, 2	Enrichment	SLC10A1	1.63
148	Inflammatory bowel disease 13	Enrichment	ABCB1	1.63
149	Charcot-marie-tooth disease type 1g	Enrichment	PMP2	1.63
150	Neuroendocrine tumor	Enrichment	CDKN1B	1.63
151	Agammaglobulinemia 5, autosomal dominant	Enrichment	LRRC8A	1.63
152	Efavirenz, poor metabolism of	Enrichment	CYP2B6	1.63
153	Apolipoprotein c-iii deficiency	Enrichment	APOC3	1.63
154	Thrombophilia due to thrombomodulin defect	Enrichment	THBD	1.63
155	Plasma triglyceride level quantitative trait locus	Enrichment	ANGPTL4	1.63
156	Immunodeficiency 29	Enrichment	IL12B	1.63
157	Oculomotor-abducens synkinesis	Enrichment	ACKR3	1.63
158	Leukoencephalopathy with dystonia and motor neuropathy	Enrichment	SCP2	1.63
159	Cholestasis, progressive familial intrahepatic, 5	Enrichment	NR1H4	1.63
160	Autoimmune disease, multisystem, infantile-onset, 1	Enrichment	STAT3	1.63
161	Congenital anomalies of kidney and urinary tract 3	Enrichment	NRIP1	1.63
162	Thrombocytopenia 6	Enrichment	SRC	1.63
163	Vitamin d-dependent rickets, type 3	Enrichment	CYP3A4	1.63
164	Deficiency in anterior pituitary function - variable immunodeficiency syndrome	Enrichment	NFKB2	1.63
165	Hypercholanemia, familial 3	Enrichment	BAAT	1.63
166	Hypercholesterolemia due to cholesterol 7alpha-hydroxylase deficiency	Enrichment	CYP7A1	1.63
167	Familial behcet-like autoinflammatory syndrome	Enrichment	TNFAIP3	1.63
168	Rickets	Enrichment	VDR	1.63
169	Stat3-related early-onset multisystem autoimmune disease	Enrichment	STAT3	1.63
170	Medium-chain acyl-coenzyme a dehydrogenase deficiency	Enrichment	ACADM	1.63
171	Intrauterine growth restriction-short stature-early adult-onset diabetes syndrome	Enrichment	CDKN1C	1.63
172	Aapoaii amyloidosis	Enrichment	APOA2	1.63
173	Chronic lymphoproliferative disorder of natural killer cells	Enrichment	STAT3	1.63
174	Asthma	Enrichment	FKBP5, TNF	1.59
175	Arterial tortuosity syndrome	Enrichment	SLC2A10	1.51
176	Dubin-johnson syndrome	Enrichment	ABCC2	1.51
177	Intellectual developmental disorder, x-linked 109	Enrichment	SERPINA1	1.51
178	Glut1 deficiency syndrome 2	Enrichment	SLC2A1	1.51
179	Congenital disorder of glycosylation, type iin	Enrichment	SLC39A8	1.51
180	Chromosome 17q23.1-q23.2 deletion syndrome	Enrichment	SLC2A1	1.51
181	Familial renal glucosuria	Enrichment	SLC5A2	1.51
182	Loeys-dietz syndrome 1	Enrichment	TGFBR2	1.51
183	Developmental and epileptic encephalopathy 94	Enrichment	SLC6A1	1.51
184	Lung cancer	Enrichment	CYP2A6, EGFR, NFE2L2	1.43
185	Huntington disease	Enrichment	SLC2A3	1.39
186	Paget disease of bone 2, early-onset	Enrichment	SQSTM1	1.39
187	Bestrophinopathy, autosomal recessive	Enrichment	FTH1	1.39
188	Paget's disease of bone 2	Enrichment	SQSTM1	1.39
189	Atypical glycine encephalopathy	Enrichment	SLC6A9	1.39
190	Burkitt lymphoma	Enrichment	MYC	1.34
191	Hyperlipoproteinemia, type v	Enrichment	APOA5	1.34
192	Glaucoma 1, open angle, a	Enrichment	CYP1B1	1.34
193	Galactosemia ii	Enrichment	NR3C1	1.34
194	Thiamine-responsive megaloblastic anemia syndrome	Enrichment	SLC19A2	1.34
195	Carnitine palmitoyltransferase ii deficiency, infantile	Enrichment	CPT2	1.34
196	Cornelia de lange syndrome 2	Enrichment	SMC1A	1.34
197	3mc syndrome 2	Enrichment	SLC26A2	1.34
198	Piebald trait	Enrichment	SNAI2	1.34
199	Carnitine palmitoyltransferase ii deficiency, lethal neonatal	Enrichment	CPT2	1.34
200	Cholestasis, benign recurrent intrahepatic, 2	Enrichment	ABCB11	1.34
201	Holoprosencephaly 5	Enrichment	ZIC2	1.34
202	Intrauterine growth retardation, metaphyseal dysplasia, adrenal hypoplasia congenita, and genital anomalies	Enrichment	CDKN1C	1.34
203	Neurodevelopmental disorder with hypotonia, speech delay, and dysmorphic facies	Enrichment	POLK	1.34
204	Cholestasis, progressive familial intrahepatic, 4	Enrichment	ABCB11	1.34
205	Carnitine palmitoyltransferase i deficiency	Enrichment	CPT1A	1.34
206	Immunodeficiency, common variable, 10	Enrichment	NFKB2	1.34
207	Autoinflammatory syndrome, familial, behcet-like 1	Enrichment	TNFAIP3	1.34
208	Carnitine palmitoyltransferase ii deficiency, myopathic, stress-induced	Enrichment	CPT2	1.34
209	Multiple endocrine neoplasia, type iv	Enrichment	CDKN1B	1.34
210	Anterior segment dysgenesis 6	Enrichment	CYP1B1	1.34
211	Encephalopathy, acute, infection-induced 4	Enrichment	CPT2	1.34
212	Cholestasis, progressive familial intrahepatic, 2	Enrichment	ABCB11	1.34
213	Sitosterolemia 2	Enrichment	ABCG5	1.34
214	Menke-hennekam syndrome 2	Enrichment	EP300	1.34
215	Immunodeficiency 127	Enrichment	TNF	1.34
216	Short-rib thoracic dysplasia 15 with polydactyly	Enrichment	ABCG5	1.34
217	Acromegaly	Enrichment	AIP	1.34
218	Hypoalphalipoproteinemia, primary, 2, intermediate	Enrichment	APOA1	1.34
219	Amyloidosis, hereditary systemic 3	Enrichment	APOA1	1.34
220	Rolandic epilepsy-speech dyspraxia syndrome	Enrichment	SRPX2	1.34
221	Primary congenital glaucoma	Enrichment	CYP1B1	1.34
222	Null pituitary adenoma	Enrichment	AIP	1.34
223	Acute necrotizing encephalopathy of childhood	Enrichment	CPT2	1.34
224	Familial isolated pituitary adenoma	Enrichment	AIP	1.34
225	Silent pituitary adenoma	Enrichment	AIP	1.34
226	Pseudohypoaldosteronism	Enrichment	SCNN1A	1.34
227	Gigantism	Enrichment	AIP	1.34
228	Cataract 6, multiple types	Enrichment	EPHA2	1.29
229	Macular dystrophy, vitelliform, 2	Enrichment	FTH1	1.29
230	Anemia, congenital, nonspherocytic hemolytic, 1	Enrichment	G6PD	1.29
231	Megalencephalic leukoencephalopathy with subcortical cysts 1	Enrichment	GSTT2	1.29
232	Hyperekplexia	Enrichment	SLC6A5	1.29
233	Aniridia	Enrichment	EPHA2	1.29
234	Rare isolated myopia	Enrichment	SLC39A5	1.29
235	Colorectal cancer	Enrichment	BAX, CCND1, EP300, NFE2L2, SRC	1.29
236	Atrial septal defect 1	Enrichment	TGFB2	1.22
237	Pseudoxanthoma elasticum	Enrichment	ABCC2	1.22
238	Anxiety	Enrichment	SLC6A4	1.22
239	Inflammatory bowel disease 25, autosomal recessive	Enrichment	TGFB1	1.22
240	Familial thyroid dyshormonogenesis	Enrichment	SLC5A5	1.22
241	Keratoconus	Enrichment	ALDH3A1	1.22
242	Il10-related early-onset inflammatory bowel disease	Enrichment	TGFB1	1.22
243	Human immunodeficiency virus type 1	Enrichment	CCL2, IFNG	1.19
244	Semilobar holoprosencephaly	Enrichment	SMC1A, ZIC2	1.19
245	Benign epilepsy with centrotemporal spikes	Enrichment	SLC2A1, SLC6A1	1.17
246	Hyper-ige syndrome 1, autosomal dominant, with recurrent infections	Enrichment	STAT3	1.17
247	Hyperalphalipoproteinemia 1	Enrichment	APOC3	1.17
248	Liddle syndrome 1	Enrichment	SCNN1A	1.17
249	Hyperbilirubinemia, rotor type	Enrichment	SLCO1B1	1.17
250	Takayasu arteritis	Enrichment	IL12B	1.17
251	D-bifunctional protein deficiency	Enrichment	EHHADH	1.17
252	Tuberous sclerosis 1	Enrichment	IFNG	1.17
253	Ifap syndrome 1, with or without bresheck syndrome	Enrichment	SREBF1	1.17
254	Pseudohypoaldosteronism, type ib1, autosomal recessive	Enrichment	SCNN1A	1.17
255	Psoriatic arthritis	Enrichment	TNF	1.17
256	Hepatitis c virus	Enrichment	IFNG	1.17
257	Estrogen resistance	Enrichment	ESR1	1.17
258	Tuberous sclerosis 2	Enrichment	IFNG	1.17
259	Pituitary adenoma 1, multiple types	Enrichment	AIP	1.17
260	Neonatal nephrocutaneous inflammatory syndrome	Enrichment	EGFR	1.17
261	Hypoalphalipoproteinemia, primary, 2	Enrichment	APOA1	1.17
262	Breast implant-associated anaplastic large cell lymphoma	Enrichment	STAT3	1.17
263	Hyper ige syndrome	Enrichment	STAT3	1.17
264	High-grade b-cell lymphoma double-hit/triple-hit	Enrichment	MYC	1.17
265	Dedifferentiated liposarcoma	Enrichment	CDK4	1.17
266	T-cell acute lymphoblastic leukemia	Enrichment	BAX	1.17
267	Growth hormone secreting pituitary adenoma	Enrichment	AIP	1.17
268	Spastic paraplegia 50, autosomal recessive	Enrichment	APOA1	1.17
269	Aip familial isolated pituitary adenomas	Enrichment	AIP	1.17
270	Neonatal inflammatory skin and bowel disease	Enrichment	EGFR	1.17
271	Phosphoenolpyruvate carboxykinase deficiency	Enrichment	PCK1	1.17
272	Well-differentiated liposarcoma	Enrichment	CDK4	1.17
273	Type 2 diabetes mellitus	Enrichment	SLC2A2, SLC2A4	1.15
274	Esophageal cancer	Enrichment	TGFBR2	1.15
275	Retinal degeneration	Enrichment	SLC6A6	1.15
276	Megacolon	Enrichment	SLC6A6	1.15
277	Paroxysmal dystonia	Enrichment	SLC2A1	1.15
278	Diffuse large b-cell lymphoma	Enrichment	FOXO1, STAT3	1.15
279	Centralopathic epilepsy	Enrichment	SLC2A1, SLC6A1	1.13
280	Basal ganglia calcification, idiopathic, 1	Enrichment	PDGFB	1.10
281	Methylmalonic aciduria and homocystinuria, cblc type	Enrichment	PRDX1	1.10
282	Orthostatic intolerance	Enrichment	SLC6A2	1.10
283	Glycine encephalopathy 1	Enrichment	SLC6A9	1.10
284	Alternating hemiplegia of childhood	Enrichment	SLC2A1	1.10
285	Early-onset posterior polar cataract	Enrichment	EPHA2	1.10
286	Hypertriglyceridemia 1	Enrichment	APOA5	1.05
287	Glaucoma 3, primary infantile, b	Enrichment	CYP1B1	1.05
288	Hypoalphalipoproteinemia, primary, 1	Enrichment	APOA1	1.05
289	Immunodeficiency, common variable, 1	Enrichment	NFKB2	1.05
290	Mantle cell lymphoma	Enrichment	CCND1	1.05
291	Arthrogryposis multiplex congenita 3, myogenic type	Enrichment	ESR1	1.05
292	Prolactinoma	Enrichment	AIP	1.05
293	Hydrocephalus, congenital, 2, with or without brain or eye anomalies	Enrichment	ACADM	1.05
294	Idiopathic bronchiectasis	Enrichment	SCNN1A	1.05
295	Coronary artery anomaly	Enrichment	APOC3	1.05
296	Cerebral malaria	Enrichment	TNF	1.05
297	Silver-russell syndrome due to a point mutation	Enrichment	CDKN1C	1.05
298	Primary hyperparathyroidism	Enrichment	CDKN1B	1.05
299	Primary fanconi renotubular syndrome	Enrichment	EHHADH	1.05
300	Hereditary angioedema with normal c1inh not related to f12 or plg variant	Enrichment	MYOF	1.05
301	Behavioral variant of frontotemporal dementia	Enrichment	SQSTM1	1.05
302	Malaria	Enrichment	G6PD, TNF	1.01
303	Frontotemporal dementia and/or amyotrophic lateral sclerosis 1	Enrichment	SQSTM1	1.00
304	Meningioma, familial	Enrichment	PDGFB	0.96
305	Presynaptic congenital myasthenic syndromes	Enrichment	SLC5A7	0.96
306	Lymphoma, mucosa-associated lymphoid type	Enrichment	BIRC3	0.96
307	Amyloidosis, hereditary systemic 2	Enrichment	APOA1	0.96
308	Von hippel-lindau syndrome	Enrichment	CCND1	0.96
309	Vitamin d-dependent rickets, type 2a	Enrichment	VDR	0.96
310	Rhabdomyosarcoma 2	Enrichment	FOXO1	0.96
311	Major depressive disorder	Enrichment	FKBP5	0.96
312	Rubinstein-taybi syndrome 2	Enrichment	EP300	0.96
313	Holoprosencephaly	Enrichment	ZIC2	0.96
314	Juvenile glaucoma	Enrichment	CYP1B1	0.96
315	Vascular dementia	Enrichment	TNF	0.96
316	Idiopathic aplastic anemia	Enrichment	IFNG	0.96
317	Familial cerebral saccular aneurysm	Enrichment	TGFBR3	0.96
318	Congenital hypothyroidism	Enrichment	SLC5A5	0.93
319	Meningioma	Enrichment	PDGFB	0.93
320	Congenital long qt syndrome	Enrichment	SLC2A2	0.93
321	Glaucoma, primary open angle	Enrichment	CYP1B1	0.88
322	Cowden syndrome 1	Enrichment	EGFR	0.88
323	Rubinstein-taybi syndrome 1	Enrichment	EP300	0.88
324	Holoprosencephaly 1	Enrichment	ZIC2	0.88
325	Wiedemann-steiner syndrome	Enrichment	SMC1A	0.88
326	Anterior segment dysgenesis 5	Enrichment	CYP1B1	0.88
327	Chromosome 16p13.3 deletion syndrome, proximal	Enrichment	EP300	0.88
328	Lung squamous cell carcinoma	Enrichment	EGFR	0.88
329	Atypical hemolytic uremic syndrome with complement gene abnormality	Enrichment	THBD	0.88
330	Generalized epilepsy with febrile seizures plus	Enrichment	FGF13	0.87
331	Cataract	Enrichment	EPHA2	0.87
332	Lynch syndrome	Enrichment	TGFBR2	0.84
333	Multiple endocrine neoplasia, type i	Enrichment	CDKN1B	0.82
334	Glaucoma 3, primary congenital, a	Enrichment	CYP1B1	0.82
335	Myelofibrosis	Enrichment	SRC	0.82
336	Squamous cell carcinoma, head and neck	Enrichment	EGFR	0.82
337	Polymicrogyria, bilateral perisylvian, x-linked	Enrichment	SRPX2	0.82
338	Waardenburg syndrome, type 2e	Enrichment	SNAI2	0.82
339	Common variable immunodeficiency	Enrichment	NFKB2	0.82
340	Cataract 44	Enrichment	EPHA2	0.79
341	Connective tissue disease	Enrichment	SLC26A2, TGFBR2	0.77
342	Rett syndrome, congenital variant	Enrichment	SMC1A	0.77
343	Permanent neonatal diabetes mellitus	Enrichment	STAT3	0.77
344	Childhood-onset schizophrenia	Enrichment	GPR153	0.77
345	Early-onset nuclear cataract	Enrichment	EPHA2	0.77
346	Neuropathy, hereditary motor and sensory, okinawa type	Enrichment	SLC5A7	0.74
347	Cornelia de lange syndrome 1	Enrichment	SMC1A	0.72
348	Charge syndrome	Enrichment	EP300	0.72
349	Bilateral perisylvian polymicrogyria	Enrichment	SRPX2	0.72
350	Primary hyperaldosteronism	Enrichment	NR3C1	0.72
351	Primary biliary cholangitis	Enrichment	IL12A	0.72
352	Cornelia de lange syndrome	Enrichment	SMC1A	0.72
353	Tooth agenesis	Enrichment	TGFA	0.69
354	Leukemia, chronic lymphocytic	Enrichment	CCND1	0.68
355	Peters-plus syndrome	Enrichment	CYP1B1	0.68
356	Stroke, ischemic	Enrichment	ALOX5AP	0.68
357	Aplastic anemia	Enrichment	IFNG	0.68
358	Autosomal non-syndromic agammaglobulinemia	Enrichment	LRRC8A	0.68
359	Migraine with or without aura 1	Enrichment	ESR1	0.64
360	Epilepsy, idiopathic generalized	Enrichment	ABCB1	0.64
361	Osteochondrodysplasia	Enrichment	SLC26A2	0.64
362	Lung non-small cell carcinoma	Enrichment	EGFR	0.64
363	Systemic lupus erythematosus	Enrichment	TNF, TNFAIP3	0.64
364	Developmental and epileptic encephalopathy 1	Enrichment	SLC2A1	0.64
365	Lip and oral cavity carcinoma	Enrichment	EGFR	0.61
366	Strabismus	Enrichment	SLC2A1	0.61
367	Breast cancer	Enrichment	ESR1, IL2, JUN	0.60
368	Hypercholesterolemia, familial, 1	Enrichment	APOA2	0.58
369	Acute promyelocytic leukemia	Enrichment	STAT3	0.58
370	Alzheimer's disease	Enrichment	TNF	0.58
371	Gastric cancer	Enrichment	CDK4, IL1B	0.58
372	Long qt syndrome 1	Enrichment	SLC2A2	0.57
373	Multiple sclerosis	Enrichment	NR1H3	0.55
374	Osteoporosis	Enrichment	SRC	0.55
375	Lung cancer susceptibility 3	Enrichment	EGFR	0.55
376	Polydactyly, postaxial, type a1	Enrichment	EP300	0.53
377	Anterior segment dysgenesis	Enrichment	CYP1B1	0.53
378	Familial hypercholesterolemia	Enrichment	APOA2	0.53
379	Rare genetic intellectual disability	Enrichment	EP300	0.53
380	Septopreoptic holoprosencephaly	Enrichment	ZIC2	0.53
381	Midline interhemispheric variant of holoprosencephaly	Enrichment	ZIC2	0.53
382	Sensorineural hearing loss	Enrichment	HGF, SLC19A2	0.51
383	Thrombocytopenia	Enrichment	SRC, THBD	0.51
384	Gliosarcoma	Enrichment	EGFR	0.50
385	Microform holoprosencephaly	Enrichment	ZIC2	0.50
386	Lobar holoprosencephaly	Enrichment	ZIC2	0.50
387	Microcephaly	Enrichment	EP300, SLC2A1, SMC1A, ZIC2	0.49
388	Body mass index quantitative trait locus 11	Enrichment	NR0B2, SLC6A14	0.49
389	Hypertension, essential	Enrichment	CYP3A5	0.48
390	Melanoma, cutaneous malignant 1	Enrichment	CDK4	0.48
391	Giant cell glioblastoma	Enrichment	EGFR	0.48
392	Alobar holoprosencephaly	Enrichment	ZIC2	0.48
393	Epilepsy	Enrichment	SLC2A1	0.47
394	Beckwith-wiedemann syndrome	Enrichment	CDKN1C	0.46
395	Charcot-marie-tooth disease type 4	Enrichment	FGD4	0.46
396	Familial isolated dilated cardiomyopathy	Enrichment	ANKRD1, CAP2	0.46
397	Arteriovenous malformations of the brain	Enrichment	EGFR	0.44
398	Behcet syndrome	Enrichment	IL12A	0.44
399	Inherited cancer-predisposing syndrome	Enrichment	AIP, CDK4, CDKN1B, EGFR	0.43
400	West syndrome	Enrichment	SLC2A1	0.43
401	Myeloma, multiple	Enrichment	CCND1, RXRA	0.43
402	Williams-beuren syndrome	Enrichment	CDKN1C	0.43
403	Frontotemporal dementia and/or amyotrophic lateral sclerosis 7	Enrichment	PPARGC1A, SQSTM1	0.41
404	Hepatocellular carcinoma	Enrichment	VDR	0.39
405	Autosomal dominant non-syndromic intellectual disability	Enrichment	SLC6A1	0.39
406	Precursor t-cell acute lymphoblastic leukemia	Enrichment	MYC	0.38
407	Ear malformation	Enrichment	SLC19A2	0.37
408	Congenital nervous system abnormality	Enrichment	CPT2, SMC1A, ZIC2	0.35
409	Nervous system disease	Enrichment	CPT2, SMC1A, ZIC2	0.35
410	Brugada syndrome	Enrichment	SCNN1A	0.34
411	Bladder cancer	Enrichment	EGFR	0.31
412	Hirschsprung disease 1	Enrichment	SREBF1	0.31
413	Prostate cancer	Enrichment	POLK	0.31
414	Peripheral nervous system disease	Enrichment	PMP2	0.28
415	Neuropathy	Enrichment	PMP2	0.28
416	Short-rib thoracic dysplasia 1 with or without polydactyly	Enrichment	ABCG5	0.27
417	Cakut	Enrichment	NRIP1	0.26
418	Non-syndromic x-linked intellectual disability	Enrichment	SMARCA1	0.24
419	Rare autosomal recessive non-syndromic sensorineural deafness type dfnb	Enrichment	HGF	0.22
420	Hereditary breast carcinoma	Enrichment	ESR1	0.19
421	Ovarian cancer	Enrichment	CDKN1B, EGFR	0.16
422	Hereditary breast ovarian cancer syndrome	Enrichment	PLK2	0.14
423	Hereditary retinal dystrophy	Enrichment	FTH1, SLC6A6	0.09
424	Fundus dystrophy	Enrichment	FTH1, SLC6A6	0.09
425	Retinitis pigmentosa	Enrichment	AHR	0.00

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Nuclear receptors meta-pathway

Pathway Network for Nuclear receptors meta-pathway

Member Pathways for Nuclear receptors meta-pathway

Pathways in the Nuclear receptors meta-pathway SuperPath

Associated Genes for Nuclear receptors meta-pathway

Associated Disorders for Nuclear receptors meta-pathway

Disorders associated with Nuclear receptors meta-pathway SuperPath

STRING Interaction Network for Nuclear receptors meta-pathway

Sources for Nuclear receptors meta-pathway