Nuclear RNA decay

No Pathway Network information available for Nuclear RNA decay

Pathways in the Nuclear RNA decay SuperPath

#	Name	Source	Genes
1	Nuclear RNA decay	Reactome	C1D DIS3 DXO EXOSC1 EXOSC10 EXOSC2 EXOSC3 EXOSC4 EXOSC5 EXOSC6 EXOSC7 EXOSC8 EXOSC9 MPHOSPH6 MTREX NCBP1 NCBP2 PABPN1 PAPOLG RBM26 RBM27 RBM7 SRRT TENT4A TENT4B WDR82 XRN2 YTHDC1 YTHDC2 ZC3H18 ZC3H3 ZC3H4 ZCCHC7 ZCCHC8 ZFC3H1 (see all 35) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	RBM7	RNA Binding Motif Protein 7	Protein Coding	1
2	MPHOSPH6	M-Phase Phosphoprotein 6	Protein Coding	1
3	C1D	C1D Nuclear Receptor Corepressor	Protein Coding	1
4	TENT4A	Terminal Nucleotidyltransferase 4A	Protein Coding	1
5	EXOSC8	Exosome Component 8	Protein Coding	1
6	EXOSC6	Exosome Component 6	Protein Coding	1
7	ZC3H18	Zinc Finger CCCH-Type Containing 18	Protein Coding	1
8	DXO	Decapping Exoribonuclease	Protein Coding	1
9	ZFC3H1	Zinc Finger C3H1-Type Containing	Protein Coding	1
10	XRN2	5''-3'' Exoribonuclease 2	Protein Coding	1
11	DIS3	DIS3 Exosome Endoribonuclease And 3''''-5'''' Exoribonuclease	Protein Coding	1
12	NCBP2	Nuclear Cap Binding Protein Subunit 2	Protein Coding	1
13	EXOSC7	Exosome Component 7	Protein Coding	1
14	ZC3H3	Zinc Finger CCCH-Type Containing 3	Protein Coding	1
15	ZC3H4	Zinc Finger CCCH-Type Containing 4	Protein Coding	1
16	EXOSC2	Exosome Component 2	Protein Coding	1
17	MTREX	Mtr4 Exosome RNA Helicase	Protein Coding	1
18	NCBP1	Nuclear Cap Binding Protein Subunit 1	Protein Coding	1
19	EXOSC3	Exosome Component 3	Protein Coding	1
20	EXOSC1	Exosome Component 1	Protein Coding	1
21	SRRT	Serrate, RNA Effector Molecule	Protein Coding	1
22	EXOSC9	Exosome Component 9	Protein Coding	1
23	EXOSC10	Exosome Component 10	Protein Coding	1
24	RBM27	RNA Binding Motif Protein 27	Protein Coding	1
25	EXOSC4	Exosome Component 4	Protein Coding	1
26	ZCCHC8	Zinc Finger CCHC-Type Containing 8	Protein Coding	1
27	EXOSC5	Exosome Component 5	Protein Coding	1
28	RBM26	RNA Binding Motif Protein 26	Protein Coding	1
29	TENT4B	Terminal Nucleotidyltransferase 4B	Protein Coding	1
30	YTHDC2	YTH N6-Methyladenosine RNA Binding Protein C2	Protein Coding	1
31	PAPOLG	Poly(A) Polymerase Gamma	Protein Coding	1
32	WDR82	WD Repeat Domain 82	Protein Coding	1
33	PABPN1	Poly(A) Binding Protein Nuclear 1	Protein Coding	1
34	ZCCHC7	Zinc Finger CCHC-Type Containing 7	Protein Coding	1
35	YTHDC1	YTH N6-Methyladenosine RNA Binding Protein C1	Protein Coding	1

Disorders associated with Nuclear RNA decay SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Pontocerebellar hypoplasia, type 1e	Enrichment	EXOSC3, EXOSC8, EXOSC9	6.50
2	Pontocerebellar hypoplasia	Enrichment	EXOSC3, EXOSC9	3.02
3	Pontocerebellar hypoplasia, type 1f	Enrichment	EXOSC1	2.59
4	Cerebellar ataxia, brain abnormalities, and cardiac conduction defects	Enrichment	EXOSC5	2.59
5	Pontocerebellar hypoplasia, type 1c	Enrichment	EXOSC8	2.59
6	Pontocerebellar hypoplasia, type 1d	Enrichment	EXOSC9	2.59
7	Short stature, hearing loss, retinitis pigmentosa, and distinctive facies	Enrichment	EXOSC2	2.59
8	Pulmonary fibrosis and/or bone marrow failure syndrome, telomere-related, 5	Enrichment	ZCCHC8	2.59
9	Congenital pontocerebellar hypoplasia type 1	Enrichment	EXOSC3	2.29
10	Oculopharyngeal muscular dystrophy 1	Enrichment	PABPN1	2.11
11	Pontocerebellar hypoplasia, type 1b	Enrichment	EXOSC3	2.11
12	Cerebellar disease	Enrichment	EXOSC3	2.11
13	Inherited acute myeloid leukemia	Enrichment	ZCCHC8	1.89
14	Congenital myopathy	Enrichment	EXOSC3	1.32
15	Dyskeratosis congenita	Enrichment	ZCCHC8	1.32
16	Lissencephaly	Enrichment	EXOSC3	1.28
17	Fetal akinesia deformation sequence 1	Enrichment	EXOSC3	1.04
18	Spastic ataxia	Enrichment	EXOSC8	0.89
19	Myeloma, multiple	Enrichment	DIS3	0.87
20	Congenital nervous system abnormality	Enrichment	EXOSC3	0.62
21	Nervous system disease	Enrichment	EXOSC3	0.62
22	Microcephaly	Enrichment	EXOSC3	0.56

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Pathway Network for Nuclear RNA decay

Member Pathways for Nuclear RNA decay

Pathways in the Nuclear RNA decay SuperPath

Associated Genes for Nuclear RNA decay

Associated Disorders for Nuclear RNA decay

Disorders associated with Nuclear RNA decay SuperPath

STRING Interaction Network for Nuclear RNA decay

Sources for Nuclear RNA decay