Nur77 Signaling in T-Cell

No Pathway Network information available for Nur77 Signaling in T-Cell

Pathways in the Nur77 Signaling in T-Cell SuperPath

#	Name	Source	Genes
1	Nur77 Signaling in T-Cell	QIAGEN	APAF1 BCL2 CABIN1 CALM1 CALM2 CALM3 CASP3 CASP9 CD247 CD28 CD3D CD3E CD3G CD80 CD86 CYCS EP300 HDAC1 HDAC2 HDAC9 MAP2K5 MAP3K2 MAP3K3 MAPK7 MEF2D NFATC1 NR4A1 PPP3CA PPP3CB PPP3CC PPP3R1 PPP3R2 RXRA SIN3A SIN3B (see all 35) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	APAF1	Apoptotic Peptidase Activating Factor 1	Protein Coding	1
2	BCL2	BCL2 Apoptosis Regulator	Protein Coding	1
3	CABIN1	Calcineurin Binding Protein 1	Protein Coding	1
4	CALM1	Calmodulin 1	Protein Coding	1
5	CALM2	Calmodulin 2	Protein Coding	1
6	CALM3	Calmodulin 3	Protein Coding	1
7	CASP3	Caspase 3	Protein Coding	1
8	CASP9	Caspase 9	Protein Coding	1
9	CD28	CD28 Molecule	Protein Coding	1
10	CD3D	CD3 Delta Subunit Of T-Cell Receptor Complex	Protein Coding	1
11	CD3E	CD3 Epsilon Subunit Of T-Cell Receptor Complex	Protein Coding	1
12	CD3G	CD3 Gamma Subunit Of T-Cell Receptor Complex	Protein Coding	1
13	CD247	CD247 Molecule	Protein Coding	1
14	CD80	CD80 Molecule	Protein Coding	1
15	CD86	CD86 Molecule	Protein Coding	1
16	CYCS	Cytochrome C, Somatic	Protein Coding	1
17	EP300	EP300 Lysine Acetyltransferase	Protein Coding	1
18	HDAC1	Histone Deacetylase 1	Protein Coding	1
19	HDAC2	Histone Deacetylase 2	Protein Coding	1
20	HDAC9	Histone Deacetylase 9	Protein Coding	1
21	MAP2K5	Mitogen-Activated Protein Kinase Kinase 5	Protein Coding	1
22	MAP3K2	Mitogen-Activated Protein Kinase Kinase Kinase 2	Protein Coding	1
23	MAP3K3	Mitogen-Activated Protein Kinase Kinase Kinase 3	Protein Coding	1
24	MAPK7	Mitogen-Activated Protein Kinase 7	Protein Coding	1
25	MEF2D	Myocyte Enhancer Factor 2D	Protein Coding	1
26	NFATC1	Nuclear Factor Of Activated T Cells 1	Protein Coding	1
27	NR4A1	Nuclear Receptor Subfamily 4 Group A Member 1	Protein Coding	1
28	PPP3CA	Protein Phosphatase 3 Catalytic Subunit Alpha	Protein Coding	1
29	PPP3CB	Protein Phosphatase 3 Catalytic Subunit Beta	Protein Coding	1
30	PPP3CC	Protein Phosphatase 3 Catalytic Subunit Gamma	Protein Coding	1
31	PPP3R1	Protein Phosphatase 3 Regulatory Subunit B, Alpha	Protein Coding	1
32	PPP3R2	Protein Phosphatase 3 Regulatory Subunit B, Beta	Protein Coding	1
33	RXRA	Retinoid X Receptor Alpha	Protein Coding	1
34	SIN3A	SIN3 Transcription Regulator Family Member A	Protein Coding	1
35	SIN3B	SIN3 Transcription Regulator Family Member B	Protein Coding	1

Disorders associated with Nur77 Signaling in T-Cell SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	T-b+ severe combined immunodeficiency due to cd3delta/cd3epsilon/cd3zeta	Enrichment	CD247, CD3D, CD3E	7.80
2	Catecholaminergic polymorphic ventricular tachycardia	Enrichment	CALM1, CALM2, CALM3	6.06
3	Severe combined immunodeficiency	Enrichment	CD247, CD3D, CD3E, CD3G	5.84
4	Witteveen-kolk syndrome	Enrichment	SIN3A, SIN3B	5.19
5	Long qt syndrome 1	Enrichment	CALM1, CALM2, CALM3	4.22
6	Auriculocondylar syndrome 4	Enrichment	HDAC9	2.59
7	Developmental and epileptic encephalopathy 91	Enrichment	PPP3CA	2.59
8	Arthrogryposis, cleft palate, craniosynostosis, and impaired intellectual development	Enrichment	PPP3CA	2.59
9	Immunodeficiency 18	Enrichment	CD3E	2.59
10	Immunodeficiency 25	Enrichment	CD247	2.59
11	Thrombocytopenia 4	Enrichment	CYCS	2.59
12	Long qt syndrome 16	Enrichment	CALM3	2.59
13	Immunodeficiency 123 with hpv-related verrucosis	Enrichment	CD28	2.59
14	Immunodeficiency 19, severe combined	Enrichment	CD3D	2.59
15	Long qt syndrome 15	Enrichment	CALM2	2.59
16	Chromosome 15q24 deletion syndrome	Enrichment	SIN3A	2.59
17	Cerebral cavernous malformations 5	Enrichment	MAP3K3	2.59
18	Immunodeficiency 19	Enrichment	CD3D	2.59
19	Verrucous hemangioma	Enrichment	MAP3K3	2.59
20	Long qt syndrome	Enrichment	CALM1, CALM2	2.54
21	Scoliosis, isolated 1	Enrichment	MAPK7	2.29
22	Ventricular tachycardia, catecholaminergic polymorphic, 4	Enrichment	CALM1	2.29
23	Long qt syndrome 14	Enrichment	CALM1	2.29
24	Menke-hennekam syndrome 2	Enrichment	EP300	2.29
25	Intravascular large b-cell lymphoma	Enrichment	BCL2	2.29
26	Immunodeficiency 17	Enrichment	CD3G	2.29
27	Mycosis fungoides	Enrichment	CD28	2.11
28	High-grade b-cell lymphoma double-hit/triple-hit	Enrichment	BCL2	2.11
29	Saczary syndrome	Enrichment	CD28	2.11
30	Rubinstein-taybi syndrome 2	Enrichment	EP300	1.89
31	Follicular lymphoma	Enrichment	BCL2	1.89
32	Autosomal thrombocytopenia with normal platelets	Enrichment	CYCS	1.89
33	Rubinstein-taybi syndrome 1	Enrichment	EP300	1.81
34	Chromosome 16p13.3 deletion syndrome, proximal	Enrichment	EP300	1.81
35	Ventricular tachycardia, catecholaminergic polymorphic, 1, with or without atrial dysfunction and/or dilated cardiomyopathy	Enrichment	CALM1	1.81
36	Oligoarticular juvenile idiopathic arthritis	Enrichment	CD247	1.75
37	Rheumatoid factor-negative juvenile idiopathic arthritis	Enrichment	CD247	1.75
38	Catecholaminergic polymorphic ventricular tachycardia 1	Enrichment	CALM1	1.69
39	Charge syndrome	Enrichment	EP300	1.64
40	Polydactyly, postaxial, type a1	Enrichment	EP300	1.42
41	Rare genetic intellectual disability	Enrichment	EP300	1.42
42	Sudden infant death syndrome	Enrichment	CALM2	1.37
43	Thrombocytopenia	Enrichment	CYCS	0.93
44	Autosomal dominant non-syndromic intellectual disability	Enrichment	PPP3CA	0.92
45	Myeloma, multiple	Enrichment	RXRA	0.87
46	Undetermined early-onset epileptic encephalopathy	Enrichment	PPP3CA	0.87
47	Colorectal cancer	Enrichment	EP300	0.69
48	Microcephaly	Enrichment	EP300	0.56

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Nur77 Signaling in T-Cell

Pathway Network for Nur77 Signaling in T-Cell

Member Pathways for Nur77 Signaling in T-Cell

Pathways in the Nur77 Signaling in T-Cell SuperPath

Associated Genes for Nur77 Signaling in T-Cell

Associated Disorders for Nur77 Signaling in T-Cell

Disorders associated with Nur77 Signaling in T-Cell SuperPath

STRING Interaction Network for Nur77 Signaling in T-Cell

Sources for Nur77 Signaling in T-Cell