O-linked glycosylation

Pathway network for the O-linked glycosylation SuperPath

Sources:

Reactome
PubChem

Pathways in the O-linked glycosylation SuperPath

#	Name	Source	Genes
1	O-linked glycosylation	Reactome	A4GNT ADAMTS1 ADAMTS10 ADAMTS12 ADAMTS13 ADAMTS14 ADAMTS15 ADAMTS16 ADAMTS17 ADAMTS18 ADAMTS19 ADAMTS2 ADAMTS20 ADAMTS3 ADAMTS4 ADAMTS5 ADAMTS6 ADAMTS7 ADAMTS8 ADAMTS9 ADAMTSL1 ADAMTSL2 ADAMTSL3 ADAMTSL4 ADAMTSL5 B3GALNT2 B3GLCT B3GNT2 B3GNT3 B3GNT4 B3GNT5 B3GNT6 B3GNT7 B3GNT8 B3GNT9 B4GALT5 B4GALT6 B4GAT1 C1GALT1 C1GALT1C1 CFP CHST10 CHST4 CRPPA DAG1 EMID1 FKRP FKTN GALNT1 GALNT10 GALNT11 GALNT12 GALNT13 GALNT14 GALNT15 GALNT16 GALNT17 GALNT18 GALNT2 GALNT3 GALNT4 GALNT5 GALNT6 GALNT7 GALNT8 GALNT9 GALNTL5 GALNTL6 GCNT1 GCNT3 GCNT4 GCNT7 LARGE1 LARGE2 MGAT5B MMRN1 MMRN2 MUC1 MUC12 MUC13 MUC15 MUC16 MUC17 MUC19 MUC2 MUC20 MUC21 MUC3A MUC4 MUC5AC MUC5B MUC6 MUC7 MUCL1 POC1B-GALNT4 POFUT2 POFUT3 POFUT4 POMGNT1 POMGNT2 POMK POMT1 POMT2 QTGAL RXYLT1 SBSPON SEMA5A SEMA5B SLC35A1 SLC35A4 SPON1 SPON2 ST3GAL1 ST3GAL2 ST3GAL3 ST3GAL4 ST6GAL1 ST6GALNAC2 ST6GALNAC3 ST6GALNAC4 THBS1 THBS2 THSD1 THSD4 THSD7A THSD7B (see all 126) (see less)
2	O-linked glycosylation of mucins	Reactome	A4GNT B3GNT2 B3GNT3 B3GNT4 B3GNT5 B3GNT6 B3GNT7 B3GNT8 B3GNT9 B4GALT5 B4GALT6 C1GALT1 C1GALT1C1 CHST4 GALNT1 GALNT10 GALNT11 GALNT12 GALNT13 GALNT14 GALNT15 GALNT16 GALNT17 GALNT18 GALNT2 GALNT3 GALNT4 GALNT5 GALNT6 GALNT7 GALNT8 GALNT9 GALNTL5 GALNTL6 GCNT1 GCNT3 GCNT4 GCNT7 MUC1 MUC12 MUC13 MUC15 MUC16 MUC17 MUC19 MUC2 MUC20 MUC21 MUC3A MUC4 MUC5AC MUC5B MUC6 MUC7 MUCL1 POC1B-GALNT4 QTGAL ST3GAL1 ST3GAL2 ST3GAL3 ST3GAL4 ST6GAL1 ST6GALNAC2 ST6GALNAC3 ST6GALNAC4 (see all 65) (see less)
3	Defective C1GALT1C1 causes TNPS	Reactome	C1GALT1 C1GALT1C1 MUC1 MUC12 MUC13 MUC15 MUC16 MUC17 MUC19 MUC2 MUC20 MUC21 MUC3A MUC4 MUC5AC MUC5B MUC6 MUC7 MUCL1 (see all 19) (see less)
4	Defective GALNT12 causes CRCS1	Reactome	GALNT12 MUC1 MUC12 MUC13 MUC15 MUC16 MUC17 MUC19 MUC2 MUC20 MUC21 MUC3A MUC4 MUC5AC MUC5B MUC6 MUC7 MUCL1 (see all 18) (see less)
5	Defective GALNT3 causes HFTC	Reactome	GALNT3 MUC1 MUC12 MUC13 MUC15 MUC16 MUC17 MUC19 MUC2 MUC20 MUC21 MUC3A MUC4 MUC5AC MUC5B MUC6 MUC7 MUCL1 (see all 18) (see less)
6	DAG1 glycosylations	Reactome	B3GALNT2 B4GAT1 CHST10 CRPPA DAG1 FKRP FKTN LARGE1 LARGE2 MGAT5B POMGNT1 POMGNT2 POMK POMT1 POMT2 RXYLT1 SLC35A1 SLC35A4 (see all 18) (see less)
7	Matriglycan biosynthesis on DAG1	Reactome	B4GAT1 CHST10 CRPPA DAG1 FKRP FKTN LARGE1 LARGE2 POMGNT1 RXYLT1 SLC35A1 SLC35A4 (see all 12) (see less)
8	mucin core 1 and core 2 O-glycosylation	PubChem	B3GNT3 C1GALT1 GALNT1 GCNT1 GCNT3 ST3GAL1 ST3GAL2 (see all 7) (see less)
9	α-dystroglycan glycosylation	PubChem	B4GAT1 CRPPA FKRP FKTN LARGE1 LARGE2 RXYLT1 (see all 7) (see less)
10	DAG1 core M3 glycosylations	Reactome	B3GALNT2 DAG1 POMGNT2 POMK POMT1 POMT2 (see all 6) (see less)
11	DAG1 core M2 glycosylations	Reactome	DAG1 MGAT5B POMGNT1 POMT1 POMT2
12	DAG1 core M1 glycosylations	Reactome	DAG1 POMGNT1 POMT1 POMT2
13	Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3	Reactome	DAG1 POMGNT1
14	Defective LARGE causes MDDGA6 and MDDGB6	Reactome	B4GAT1 LARGE1
15	mucin core 3 and core 4 O-glycosylation	PubChem	GALNT1 GCNT3

Gene overlap in member pathways for O-linked glycosylation SuperPath

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	DAG1	Dystroglycan 1	Protein Coding	7
2	POMGNT1	Protein O-Linked Mannose N-Acetylglucosaminyltransferase 1 (Beta 1,2-)	Protein Coding	6
3	MUC12	Mucin 12, Cell Surface Associated	Protein Coding	5
4	POMT1	Protein O-Mannosyltransferase 1	Protein Coding	5
5	B4GAT1	Beta-1,4-Glucuronyltransferase 1	Protein Coding	5
6	MUCL1	Mucin Like 1	Protein Coding	5
7	MUC17	Mucin 17, Cell Surface Associated	Protein Coding	5
8	MUC15	Mucin 15, Cell Surface Associated	Protein Coding	5
9	MUC20	Mucin 20, Cell Surface Associated	Protein Coding	5
10	MUC19	Mucin 19, Oligomeric (Gene/Pseudogene)	Protein Coding	5
11	POMT2	Protein O-Mannosyltransferase 2	Protein Coding	5
12	MUC21	Mucin 21, Cell Surface Associated	Protein Coding	5
13	MUC1	Mucin 1, Cell Surface Associated	Protein Coding	5
14	MUC2	Mucin 2, Oligomeric Mucus/Gel-Forming	Protein Coding	5
15	MUC3A	Mucin 3A, Cell Surface Associated	Protein Coding	5
16	MUC4	Mucin 4, Cell Surface Associated	Protein Coding	5
17	MUC5AC	Mucin 5AC, Oligomeric Mucus/Gel-Forming	Protein Coding	5
18	MUC6	Mucin 6, Oligomeric Mucus/Gel-Forming (Gene/Pseudogene)	Protein Coding	5
19	MUC7	Mucin 7, Secreted	Protein Coding	5
20	MUC13	Mucin 13, Cell Surface Associated	Protein Coding	5
21	MUC5B	Mucin 5B, Oligomeric Mucus/Gel-Forming	Protein Coding	5
22	LARGE1	LARGE Xylosyl- And Glucuronyltransferase 1	Protein Coding	5
23	MUC16	Mucin 16, Cell Surface Associated	Protein Coding	5
24	RXYLT1	Ribitol Xylosyltransferase 1	Protein Coding	4
25	LARGE2	LARGE Xylosyl- And Glucuronyltransferase 2	Protein Coding	4
26	FKTN	Fukutin	Protein Coding	4
27	GALNT1	Polypeptide N-Acetylgalactosaminyltransferase 1	Protein Coding	4
28	C1GALT1	Core 1 Synthase, Glycoprotein-N-Acetylgalactosamine 3-Beta-Galactosyltransferase 1	Protein Coding	4
29	CRPPA	CDP-L-Ribitol Pyrophosphorylase A	Protein Coding	4
30	FKRP	Fukutin Related Protein	Protein Coding	4
31	GCNT3	Glucosaminyl (N-Acetyl) Transferase 3, Mucin Type	Protein Coding	4
32	B3GNT3	UDP-GlcNAc:BetaGal Beta-1,3-N-Acetylglucosaminyltransferase 3	Protein Coding	3
33	SLC35A1	Solute Carrier Family 35 Member A1	Protein Coding	3
34	SLC35A4	Solute Carrier Family 35 Member A4	Protein Coding	3
35	MGAT5B	Alpha-1,6-Mannosylglycoprotein 6-Beta-N-Acetylglucosaminyltransferase B	Protein Coding	3
36	B3GALNT2	Beta-1,3-N-Acetylgalactosaminyltransferase 2	Protein Coding	3
37	GALNT3	Polypeptide N-Acetylgalactosaminyltransferase 3	Protein Coding	3
38	GCNT1	Glucosaminyl (N-Acetyl) Transferase 1	Protein Coding	3
39	C1GALT1C1	C1GALT1 Specific Chaperone 1	Protein Coding	3
40	ST3GAL1	ST3 Beta-Galactoside Alpha-2,3-Sialyltransferase 1	Protein Coding	3
41	ST3GAL2	ST3 Beta-Galactoside Alpha-2,3-Sialyltransferase 2	Protein Coding	3
42	GALNT12	Polypeptide N-Acetylgalactosaminyltransferase 12	Protein Coding	3
43	POMK	Protein O-Mannose Kinase	Protein Coding	3
44	POMGNT2	Protein O-Linked Mannose N-Acetylglucosaminyltransferase 2 (Beta 1,4-)	Protein Coding	3
45	CHST10	Carbohydrate Sulfotransferase 10	Protein Coding	3
46	POC1B-GALNT4	POC1B-GALNT4 Readthrough	Protein Coding	2
47	CHST4	Carbohydrate Sulfotransferase 4	Protein Coding	2
48	ST6GALNAC2	ST6 N-Acetylgalactosaminide Alpha-2,6-Sialyltransferase 2	Protein Coding	2
49	B3GNT2	UDP-GlcNAc:BetaGal Beta-1,3-N-Acetylglucosaminyltransferase 2	Protein Coding	2
50	GALNT6	Polypeptide N-Acetylgalactosaminyltransferase 6	Protein Coding	2
51	GALNT5	Polypeptide N-Acetylgalactosaminyltransferase 5	Protein Coding	2
52	GALNT13	Polypeptide N-Acetylgalactosaminyltransferase 13	Protein Coding	2
53	GALNT15	Polypeptide N-Acetylgalactosaminyltransferase 15	Protein Coding	2
54	GCNT7	Glucosaminyl (N-Acetyl) Transferase Family Member 7	Protein Coding	2
55	QTGAL	Queuosine-TRNA Galactosyltransferase	Protein Coding	2
56	GALNTL5	Polypeptide N-Acetylgalactosaminyltransferase Like 5	Protein Coding	2
57	B3GNT6	UDP-GlcNAc:BetaGal Beta-1,3-N-Acetylglucosaminyltransferase 6	Protein Coding	2
58	ST6GALNAC3	ST6 N-Acetylgalactosaminide Alpha-2,6-Sialyltransferase 3	Protein Coding	2
59	GALNT2	Polypeptide N-Acetylgalactosaminyltransferase 2	Protein Coding	2
60	GALNT8	Polypeptide N-Acetylgalactosaminyltransferase 8	Protein Coding	2
61	ST6GALNAC4	ST6 N-Acetylgalactosaminide Alpha-2,6-Sialyltransferase 4	Protein Coding	2
62	GALNT18	Polypeptide N-Acetylgalactosaminyltransferase 18	Protein Coding	2
63	B3GNT8	UDP-GlcNAc:BetaGal Beta-1,3-N-Acetylglucosaminyltransferase 8	Protein Coding	2
64	GALNTL6	Polypeptide N-Acetylgalactosaminyltransferase Like 6	Protein Coding	2
65	GALNT9	Polypeptide N-Acetylgalactosaminyltransferase 9	Protein Coding	2
66	A4GNT	Alpha-1,4-N-Acetylglucosaminyltransferase	Protein Coding	2
67	GCNT4	Glucosaminyl (N-Acetyl) Transferase 4	Protein Coding	2
68	GALNT7	Polypeptide N-Acetylgalactosaminyltransferase 7	Protein Coding	2
69	GALNT10	Polypeptide N-Acetylgalactosaminyltransferase 10	Protein Coding	2
70	GALNT16	Polypeptide N-Acetylgalactosaminyltransferase 16	Protein Coding	2
71	GALNT11	Polypeptide N-Acetylgalactosaminyltransferase 11	Protein Coding	2
72	GALNT17	Polypeptide N-Acetylgalactosaminyltransferase 17	Protein Coding	2
73	ST6GAL1	ST6 Beta-Galactoside Alpha-2,6-Sialyltransferase 1	Protein Coding	2
74	ST3GAL4	ST3 Beta-Galactoside Alpha-2,3-Sialyltransferase 4	Protein Coding	2
75	ST3GAL3	ST3 Beta-Galactoside Alpha-2,3-Sialyltransferase 3	Protein Coding	2
76	B3GNT4	UDP-GlcNAc:BetaGal Beta-1,3-N-Acetylglucosaminyltransferase 4	Protein Coding	2
77	GALNT14	Polypeptide N-Acetylgalactosaminyltransferase 14	Protein Coding	2
78	B3GNT5	UDP-GlcNAc:BetaGal Beta-1,3-N-Acetylglucosaminyltransferase 5	Protein Coding	2
79	B3GNT9	UDP-GlcNAc:BetaGal Beta-1,3-N-Acetylglucosaminyltransferase 9	Protein Coding	2
80	GALNT4	Polypeptide N-Acetylgalactosaminyltransferase 4	Protein Coding	2
81	B3GNT7	UDP-GlcNAc:BetaGal Beta-1,3-N-Acetylglucosaminyltransferase 7	Protein Coding	2
82	B4GALT6	Beta-1,4-Galactosyltransferase 6	Protein Coding	2
83	B4GALT5	Beta-1,4-Galactosyltransferase 5	Protein Coding	2
84	SPON2	Spondin 2	Protein Coding	1
85	SPON1	Spondin 1	Protein Coding	1
86	ADAMTS13	ADAM Metallopeptidase With Thrombospondin Type 1 Motif 13	Protein Coding	1
87	ADAMTS8	ADAM Metallopeptidase With Thrombospondin Type 1 Motif 8	Protein Coding	1
88	ADAMTS5	ADAM Metallopeptidase With Thrombospondin Type 1 Motif 5	Protein Coding	1
89	ADAMTS7	ADAM Metallopeptidase With Thrombospondin Type 1 Motif 7	Protein Coding	1
90	ADAMTS6	ADAM Metallopeptidase With Thrombospondin Type 1 Motif 6	Protein Coding	1
91	EMID1	EMI Domain Containing 1	Protein Coding	1
92	ADAMTS14	ADAM Metallopeptidase With Thrombospondin Type 1 Motif 14	Protein Coding	1
93	B3GLCT	Beta 3-Glucosyltransferase	Protein Coding	1
94	SBSPON	Somatomedin B And Thrombospondin Type 1 Domain Containing	Protein Coding	1
95	POFUT4	Protein O-Fucosyltransferase 4	Protein Coding	1
96	ADAMTS15	ADAM Metallopeptidase With Thrombospondin Type 1 Motif 15	Protein Coding	1
97	ADAMTS16	ADAM Metallopeptidase With Thrombospondin Type 1 Motif 16	Protein Coding	1
98	ADAMTS17	ADAM Metallopeptidase With Thrombospondin Type 1 Motif 17	Protein Coding	1
99	ADAMTS18	ADAM Metallopeptidase With Thrombospondin Type 1 Motif 18	Protein Coding	1
100	ADAMTS19	ADAM Metallopeptidase With Thrombospondin Type 1 Motif 19	Protein Coding	1
101	THSD7A	Thrombospondin Type 1 Domain Containing 7A	Protein Coding	1
102	MMRN1	Multimerin 1	Protein Coding	1
103	POFUT2	Protein O-Fucosyltransferase 2	Protein Coding	1
104	ADAMTSL5	ADAMTS Like 5	Protein Coding	1
105	CFP	Complement Factor Properdin	Protein Coding	1
106	SEMA5B	Semaphorin 5B	Protein Coding	1
107	ADAMTSL4	ADAMTS Like 4	Protein Coding	1
108	THSD1	Thrombospondin Type 1 Domain Containing 1	Protein Coding	1
109	ADAMTS9	ADAM Metallopeptidase With Thrombospondin Type 1 Motif 9	Protein Coding	1
110	ADAMTSL3	ADAMTS Like 3	Protein Coding	1
111	THBS1	Thrombospondin 1	Protein Coding	1
112	THBS2	Thrombospondin 2	Protein Coding	1
113	MMRN2	Multimerin 2	Protein Coding	1
114	THSD4	Thrombospondin Type 1 Domain Containing 4	Protein Coding	1
115	ADAMTS20	ADAM Metallopeptidase With Thrombospondin Type 1 Motif 20	Protein Coding	1
116	THSD7B	Thrombospondin Type 1 Domain Containing 7B	Protein Coding	1
117	ADAMTS12	ADAM Metallopeptidase With Thrombospondin Type 1 Motif 12	Protein Coding	1
118	ADAMTS10	ADAM Metallopeptidase With Thrombospondin Type 1 Motif 10	Protein Coding	1
119	POFUT3	Protein O-Fucosyltransferase 3	Protein Coding	1
120	SEMA5A	Semaphorin 5A	Protein Coding	1
121	ADAMTSL1	ADAMTS Like 1	Protein Coding	1
122	ADAMTS4	ADAM Metallopeptidase With Thrombospondin Type 1 Motif 4	Protein Coding	1
123	ADAMTS3	ADAM Metallopeptidase With Thrombospondin Type 1 Motif 3	Protein Coding	1
124	ADAMTS2	ADAM Metallopeptidase With Thrombospondin Type 1 Motif 2	Protein Coding	1
125	ADAMTS1	ADAM Metallopeptidase With Thrombospondin Type 1 Motif 1	Protein Coding	1
126	ADAMTSL2	ADAMTS Like 2	Protein Coding	1

Disorders associated with O-linked glycosylation SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Hyperphosphatemia	Direct
2	Muscular dystrophy-dystroglycanopathy , type b, 1	Direct
3	Congenital muscular dystrophy	Direct
4	Walker-warburg syndrome	Enrichment	B3GALNT2, B4GAT1, CRPPA, DAG1, FKRP, FKTN, LARGE1, POMGNT1, POMGNT2, POMK, POMT1, POMT2, RXYLT1	16.00
5	Muscle eye brain disease	Enrichment	B3GALNT2, CRPPA, FKRP, FKTN, LARGE1, POMGNT1, POMT1, POMT2	16.00
6	Congenital muscular dystrophy with cerebellar involvement	Enrichment	FKRP, POMGNT1, POMK, POMT1, POMT2	16.00
7	Muscular dystrophy-dystroglycanopathy , type a, 1	Enrichment	B4GAT1, FKRP, FKTN, POMT1, POMT2	11.09
8	Congenital muscular dystrophy without intellectual disability	Enrichment	CRPPA, FKRP, FKTN, POMT1	11.00
9	Congenital muscular dystrophy with intellectual disability	Enrichment	FKRP, LARGE1, POMT1, POMT2	10.72
10	Muscular dystrophy-dystroglycanopathy	Enrichment	B3GALNT2, CRPPA, FKRP, POMGNT1	9.99
11	Congenital muscular dystrophy due to dystroglycanopathy	Enrichment	B3GALNT2, CRPPA, FKRP, POMGNT1	9.99
12	Autosomal recessive limb-girdle muscular dystrophy	Enrichment	FKRP, POMGNT1, POMT1, POMT2	8.08
13	Muscular dystrophy-dystroglycanopathy , type c, 12	Enrichment	POMK, POMT1	6.79
14	Congenital muscular dystrophy-dystroglycanopathy type a	Enrichment	POMGNT1, POMT2	6.71
15	Muscular dystrophy-dystroglycanopathy , type a, 4	Enrichment	FKRP, FKTN	6.64
16	Muscular dystrophy-dystroglycanopathy , type a, 8	Enrichment	CRPPA, POMGNT2	5.30
17	Ehlers-danlos syndrome, dermatosparaxis type	Enrichment	ADAMTS2, ADAMTSL2	4.07
18	Muscular dystrophy-dystroglycanopathy , type a, 9	Enrichment	DAG1	3.53
19	Muscular dystrophy-dystroglycanopathy , type c, 1	Enrichment	POMT1	3.53
20	Muscular dystrophy-dystroglycanopathy , type c, 9	Enrichment	DAG1	3.53
21	Muscle-eye-brain disease with bilateral multicystic leucodystrophy	Enrichment	DAG1	3.53
22	Congenital nervous system abnormality	Enrichment	POMGNT1, POMT1	3.44
23	Nervous system disease	Enrichment	POMGNT1, POMT1	3.44
24	Muscular dystrophy-dystroglycanopathy , type a, 12	Enrichment	POMK	3.35
25	Muscular dystrophy-dystroglycanopathy , type c, 8	Enrichment	POMGNT2	3.35
26	Muscular dystrophy	Enrichment	FKRP, POMT2	3.35
27	Weill-marchesani syndrome	Enrichment	ADAMTS10, ADAMTS17	3.29
28	Muscular dystrophy-dystroglycanopathy , type a, 6	Enrichment	LARGE1	3.29
29	Cardiomyopathy, dilated, 1x	Enrichment	FKTN	3.29
30	Muscular dystrophy-dystroglycanopathy , type a, 13	Enrichment	B4GAT1	3.29
31	Muscular dystrophy-dystroglycanopathy , type b, 6	Enrichment	LARGE1	3.29
32	Muscular dystrophy-dystroglycanopathy , type b, 5	Enrichment	FKRP	3.29
33	Muscular dystrophy-dystroglycanopathy , type a, 5	Enrichment	FKRP	3.29
34	Muscular dystrophy-dystroglycanopathy , type a, 10	Enrichment	RXYLT1	3.29
35	Muscular dystrophy-dystroglycanopathy , type b, 4	Enrichment	FKTN	3.29
36	Muscular dystrophy-dystroglycanopathy , type c, 4	Enrichment	FKTN	3.29
37	Muscular dystrophy-dystroglycanopathy , type a, 3	Enrichment	POMGNT1	3.23
38	Muscular dystrophy-dystroglycanopathy , type b, 3	Enrichment	POMGNT1	3.23
39	Muscular dystrophy-dystroglycanopathy , type c, 2	Enrichment	POMT2	3.23
40	Muscular dystrophy-dystroglycanopathy , type a, 2	Enrichment	POMT2	3.23
41	Muscular dystrophy-dystroglycanopathy , type b, 2	Enrichment	POMT2	3.23
42	Retinitis pigmentosa 76	Enrichment	POMGNT1	3.23
43	Congenital muscular dystrophy-dystroglycanopathy type a3	Enrichment	POMGNT1	3.23
44	Childhood-onset schizophrenia	Enrichment	B3GNT6, GALNT4	3.21
45	Muscular dystrophy-dystroglycanopathy , type c, 3	Enrichment	POMGNT1	3.05
46	Muscular dystrophy-dystroglycanopathy , type a, 11	Enrichment	B3GALNT2	3.05
47	Congenital muscular dystrophy-dystroglycanopathy type a11	Enrichment	B3GALNT2	3.05
48	Congenital disorder of glycosylation, type iif	Enrichment	SLC35A1	3.05
49	Neuronopathy, distal hereditary motor, autosomal dominant 3	Enrichment	FKRP	2.99
50	Tubulointerstitial kidney disease, autosomal dominant 2	Enrichment	MUC1	2.88
51	Colorectal cancer 1	Enrichment	GALNT12	2.88
52	Extrinsic allergic alveolitis	Enrichment	MUC5B	2.88
53	Tn polyagglutination syndrome	Enrichment	C1GALT1C1	2.85
54	Hemolytic uremic syndrome, atypical, 8, with rhizomelic short stature	Enrichment	C1GALT1C1	2.85
55	Muscular dystrophy-dystroglycanopathy , type c, 5	Enrichment	FKRP	2.81
56	Muscular dystrophy, congenital, due to integrin alpha-7 deficiency	Enrichment	CRPPA	2.81
57	Nizon-isidor syndrome	Enrichment	FKRP	2.81
58	Muscular dystrophy-dystroglycanopathy , type c, 7	Enrichment	CRPPA	2.69
59	Congenital muscular dystrophy-dystroglycanopathy type a7	Enrichment	CRPPA	2.69
60	Muscular dystrophy-dystroglycanopathy , type a, 7	Enrichment	CRPPA	2.69
61	Panbronchiolitis, diffuse	Enrichment	MUC5B	2.58
62	Hydrocephalus	Enrichment	POMGNT1	2.35
63	Limb-girdle muscular dystrophy	Enrichment	FKRP	2.33
64	Creatine phosphokinase, elevated serum	Enrichment	DAG1	2.33
65	Hydrocephalus, congenital, 1	Enrichment	POMT1	2.33
66	Isolated elevated serum creatine phosphokinase levels	Enrichment	DAG1	2.33
67	Intellectual developmental disorder, autosomal recessive 12	Enrichment	ST3GAL3	2.32
68	Congenital disorder of glycosylation, type iit	Enrichment	GALNT2	2.32
69	St3gal3-cdg	Enrichment	ST3GAL3	2.32
70	Pulmonary fibrosis	Enrichment	MUC5B	2.10
71	Atypical hemolytic-uremic syndrome	Enrichment	ADAMTS13, C1GALT1C1	2.08
72	Geleophysic dysplasia 1	Enrichment	ADAMTSL2	2.03
73	Lethal short-limb skeletal dysplasia, al gazali type	Enrichment	ADAMTSL2	2.03
74	Microcornea, myopic chorioretinal atrophy, and telecanthus	Enrichment	ADAMTS18	2.03
75	Hennekam lymphangiectasia-lymphedema syndrome 3	Enrichment	ADAMTS3	2.03
76	Properdin deficiency, x-linked	Enrichment	CFP	2.03
77	Aortic aneurysm, familial thoracic 12	Enrichment	THSD4	2.03
78	Arthrogryposis, distal, type 12	Enrichment	ADAMTS15	2.03
79	Lymphatic malformation 13	Enrichment	THSD1	2.03
80	Aneurysm, intracranial berry, 12	Enrichment	THSD1	2.03
81	Cardiac valvular dysplasia 2	Enrichment	ADAMTS19	2.03
82	Microcephaly-facial dysmorphism-ocular anomalies-multiple congenital anomalies syndrome	Enrichment	ADAMTSL1	2.03
83	Deafness, autosomal dominant 64	Enrichment	B3GNT4	2.02
84	Developmental and epileptic encephalopathy 15	Enrichment	ST3GAL3	2.02
85	Tumoral calcinosis, hyperphosphatemic, familial, 1	Enrichment	GALNT3	1.84
86	Cone-rod dystrophy 20	Enrichment	POC1B-GALNT4	1.84
87	Retinitis pigmentosa	Enrichment	LARGE1, POMGNT1	1.84
88	Asthma	Enrichment	MUC7	1.84
89	Primary ovarian insufficiency	Enrichment	ADAMTS1, ADAMTS6, THBS1	1.76
90	Cri-du-chat syndrome	Enrichment	SEMA5A	1.73
91	Ectopia lentis et pupillae	Enrichment	ADAMTSL4	1.73
92	Craniosynostosis with ectopia lentis	Enrichment	ADAMTSL4	1.73
93	Thrombotic thrombocytopenic purpura, hereditary	Enrichment	ADAMTS13	1.73
94	Ectopia lentis 2, isolated, autosomal recessive	Enrichment	ADAMTSL4	1.73
95	Thrombotic thrombocytopenic purpura	Enrichment	ADAMTS13	1.73
96	Myopathy	Enrichment	FKRP	1.69
97	Interstitial lung disease 2	Enrichment	MUC5B	1.65
98	Autosomal recessive non-syndromic intellectual disability	Enrichment	B3GALNT2	1.60
99	Familial isolated dilated cardiomyopathy	Enrichment	FKTN	1.57
100	Weill-marchesani syndrome 4	Enrichment	ADAMTS17	1.56
101	Ehlers-danlos syndrome, classic-like, 3	Enrichment	THBS2	1.56
102	Weill-marchesani syndrome 1	Enrichment	ADAMTS10	1.56
103	Isolated ectopia lentis	Enrichment	ADAMTSL4	1.56
104	Hennekam syndrome	Enrichment	ADAMTS3	1.56
105	Geleophysic dysplasia	Enrichment	ADAMTSL2	1.56
106	Severe covid-19	Enrichment	MUC5B	1.42
107	Dilated cardiomyopathy	Enrichment	FKTN	1.39
108	Familial cerebral saccular aneurysm	Enrichment	THSD1	1.34
109	46,xy disorder of sex development	Enrichment	ADAMTS16	1.26
110	Intervertebral disc disease	Enrichment	THBS2	1.20
111	Hereditary retinal dystrophy	Enrichment	POMGNT1	1.08
112	Fundus dystrophy	Enrichment	POMGNT1	1.08
113	Peters-plus syndrome	Enrichment	B3GLCT	1.05
114	Ovarian cancer	Enrichment	MUC16	0.90
115	Anterior segment dysgenesis	Enrichment	ADAMTS17	0.88
116	Male infertility	Enrichment	GALNTL5	0.82
117	Developmental and epileptic encephalopathy	Enrichment	ST3GAL3	0.80
118	Ehlers-danlos syndrome	Enrichment	THBS2	0.79
119	Non-immune hydrops fetalis	Enrichment	THSD1	0.60
120	Nephronophthisis	Enrichment	ADAMTS9	0.58
121	Familial thoracic aortic aneurysm and aortic dissection	Enrichment	THSD4	0.47
122	Thrombocytopenia	Enrichment	ADAMTS13	0.44

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

O-linked glycosylation

Pathway Network for O-linked glycosylation

Pathway network for the O-linked glycosylation SuperPath

Member Pathways for O-linked glycosylation

Pathways in the O-linked glycosylation SuperPath

Gene overlap in member pathways for O-linked glycosylation SuperPath

Associated Genes for O-linked glycosylation

Associated Disorders for O-linked glycosylation

Disorders associated with O-linked glycosylation SuperPath

STRING Interaction Network for O-linked glycosylation

Sources for O-linked glycosylation