Ondansetron Pathway, Pharmacokinetics/Pharmacodynamics
Pathways in the Ondansetron Pathway, Pharmacokinetics/Pharmacodynamics SuperPath
| # | Name | Source | Genes |
|---|---|---|---|
| 1 | Ondansetron Pathway, Pharmacokinetics/Pharmacodynamics | PharmGKB | |
| 2 | Tropisetron Pathway, Pharmacokinetics/Pharmacodynamics | PharmGKB |
Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways
| # | Symbol | Description | Category | # Related Pathways |
|---|---|---|---|---|
| 1 | HTR3B | 5-Hydroxytryptamine Receptor 3B | Protein Coding | 2 |
| 2 | HTR3A | 5-Hydroxytryptamine Receptor 3A | Protein Coding | 2 |
| 3 | CYP2D6 | Cytochrome P450 Family 2 Subfamily D Member 6 (Gene/Pseudogene) | Protein Coding | 2 |
| 4 | CYP3A4 | Cytochrome P450 Family 3 Subfamily A Member 4 | Protein Coding | 2 |
| 5 | HTR3E | 5-Hydroxytryptamine Receptor 3E | Protein Coding | 2 |
| 6 | HTR3D | 5-Hydroxytryptamine Receptor 3D | Protein Coding | 2 |
| 7 | HTR3C | 5-Hydroxytryptamine Receptor 3C | Protein Coding | 2 |
| 8 | CYP1A1 | Cytochrome P450 Family 1 Subfamily A Member 1 | Protein Coding | 1 |
| 9 | CYP1A2 | Cytochrome P450 Family 1 Subfamily A Member 2 | Protein Coding | 1 |
| 10 | SLC22A1 | Solute Carrier Family 22 Member 1 | Protein Coding | 1 |
Disorders associated with Ondansetron Pathway, Pharmacokinetics/Pharmacodynamics SuperPath
according to GeneCards Suite gene sharing
| # | Disorder | Type | Genes | Score |
|---|---|---|---|---|
| 1 | Drug metabolism, poor, cyp2d6-related | Enrichment | CYP2D6 | 3.23 |
| 2 | Vitamin d-dependent rickets, type 3 | Enrichment | CYP3A4 | 3.23 |
