OSX and miRNAs in tooth development

No Pathway Network information available for OSX and miRNAs in tooth development

Pathways in the OSX and miRNAs in tooth development SuperPath

#	Name	Source	Genes
1	OSX and miRNAs in tooth development	WikiPathways	ALPL BMP7 CTNNB1 DKK1 DMP1 DSPP HNF1A KLF4 MIR145 MIR204 MIR211 MIR29B1 MIR32 MIR338 MIR34AHG MIR586 MIR885 MIRLET7A1 MIRLET7A2 MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I NOTCH1 NOTCH2 NOTCH3 NOTCH4 RUNX2 SOST SP7 (see all 33) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	MIR586	MicroRNA 586	RNA Gene	1
2	KLF4	KLF Transcription Factor 4	Protein Coding	1
3	RUNX2	RUNX Family Transcription Factor 2	Protein Coding	1
4	HNF1A	HNF1 Homeobox A	Protein Coding	1
5	BMP7	Bone Morphogenetic Protein 7	Protein Coding	1
6	SOST	Sclerostin	Protein Coding	1
7	NOTCH4	Notch Receptor 4	Protein Coding	1
8	NOTCH3	Notch Receptor 3	Protein Coding	1
9	NOTCH2	Notch Receptor 2	Protein Coding	1
10	NOTCH1	Notch Receptor 1	Protein Coding	1
11	MIR338	MicroRNA 338	RNA Gene	1
12	MIR32	MicroRNA 32	RNA Gene	1
13	MIR211	MicroRNA 211	RNA Gene	1
14	MIR204	MicroRNA 204	RNA Gene	1
15	MIR145	MicroRNA 145	RNA Gene	1
16	MIRLET7I	MicroRNA Let-7i	RNA Gene	1
17	MIRLET7G	MicroRNA Let-7g	RNA Gene	1
18	MIRLET7E	MicroRNA Let-7e	RNA Gene	1
19	MIRLET7D	MicroRNA Let-7d	RNA Gene	1
20	MIRLET7C	MicroRNA Let-7c	RNA Gene	1
21	ALPL	Alkaline Phosphatase, Biomineralization Associated	Protein Coding	1
22	DKK1	Dickkopf Wnt Signaling Pathway Inhibitor 1	Protein Coding	1
23	DSPP	Dentin Sialophosphoprotein	Protein Coding	1
24	DMP1	Dentin Matrix Acidic Phosphoprotein 1	Protein Coding	1
25	CTNNB1	Catenin Beta 1	Protein Coding	1
26	SP7	Sp7 Transcription Factor	Protein Coding	1
27	MIR885	MicroRNA 885	RNA Gene	1
28	MIR34AHG	MIR34A Host Gene	RNA Gene	1
29	MIR29B1	MicroRNA 29b-1	RNA Gene	1
30	MIRLET7F2	MicroRNA Let-7f-2	RNA Gene	1
31	MIRLET7F1	MicroRNA Let-7f-1	RNA Gene	1
32	MIRLET7A2	MicroRNA Let-7a-2	RNA Gene	1
33	MIRLET7A1	MicroRNA Let-7a-1	RNA Gene	1

Disorders associated with OSX and miRNAs in tooth development SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Craniodiaphyseal dysplasia	Enrichment	SOST, SP7	5.24
2	Keratoacanthoma	Enrichment	NOTCH1, NOTCH2	4.76
3	Chiari malformation type i	Enrichment	DKK1	2.61
4	Hepatic adenomas, familial	Enrichment	HNF1A	2.61
5	Craniodiaphyseal dysplasia, autosomal dominant	Enrichment	SOST	2.61
6	Hypophosphatemic rickets, autosomal recessive, 1	Enrichment	DMP1	2.61
7	Sclerosteosis 1	Enrichment	SOST	2.61
8	Hypophosphatasia, adult	Enrichment	ALPL	2.61
9	Hajdu-cheney syndrome	Enrichment	NOTCH2	2.61
10	Alagille syndrome 2	Enrichment	NOTCH2	2.61
11	Dentinogenesis imperfecta 1	Enrichment	DSPP	2.61
12	Dentinogenesis imperfecta, shields type iii	Enrichment	DSPP	2.61
13	Dentin dysplasia, type ii	Enrichment	DSPP	2.61
14	Lateral meningocele syndrome	Enrichment	NOTCH3	2.61
15	Hypophosphatasia, childhood	Enrichment	ALPL	2.61
16	Deafness, autosomal dominant 39, with dentinogenesis imperfecta 1	Enrichment	DSPP	2.61
17	Myofibromatosis, infantile, 2	Enrichment	NOTCH3	2.61
18	Type 1 diabetes mellitus 20	Enrichment	HNF1A	2.61
19	Prenatal benign hypophosphatasia	Enrichment	ALPL	2.61
20	Adenoid ameloblastoma	Enrichment	CTNNB1	2.61
21	Transient cerebral ischemia	Enrichment	NOTCH3	2.61
22	Cerebral arteriopathy, autosomal recessive, with subcortical infarcts and leukoencephalopathy 1	Enrichment	NOTCH3	2.61
23	Microcystic stromal tumor	Enrichment	CTNNB1	2.61
24	Metaphyseal dysplasia with maxillary hypoplasia with or without brachydactyly	Enrichment	RUNX2	2.31
25	Van buchem disease	Enrichment	SOST	2.31
26	Osteopathia striata with cranial sclerosis	Enrichment	CTNNB1	2.31
27	Osteogenesis imperfecta, type xii	Enrichment	SP7	2.31
28	Adams-oliver syndrome 5	Enrichment	NOTCH1	2.31
29	Retinal dystrophy and iris coloboma with or without cataract	Enrichment	MIR204	2.31
30	Alpha-thalassemia/impaired intellectual development syndrome, x-linked	Enrichment	ALPL	2.31
31	Infantile myofibromatosis	Enrichment	NOTCH3	2.31
32	Autosomal recessive hypophosphatemic rickets	Enrichment	DMP1	2.31
33	Sclerosteosis	Enrichment	SOST	2.31
34	Childhood hepatocellular carcinoma	Enrichment	CTNNB1	2.31
35	Lipodystrophy, familial partial, type 1	Enrichment	NOTCH3	2.31
36	Depressive disorder	Enrichment	NOTCH3	2.31
37	Hypophosphatasia	Enrichment	ALPL	2.31
38	Alpha thalassemia-x-linked intellectual disability syndrome	Enrichment	ALPL	2.31
39	Juvenile nasopharyngeal angiofibroma	Enrichment	CTNNB1	2.31
40	Hyperinsulinism due to hnf1a deficiency	Enrichment	HNF1A	2.31
41	Dentinogenesis imperfecta	Enrichment	DSPP	2.31
42	Teratoma	Enrichment	CTNNB1	2.31
43	Cleidocranial dysplasia 1	Enrichment	RUNX2	2.14
44	Desmoid disease, hereditary	Enrichment	CTNNB1	2.14
45	Hypophosphatasia, infantile	Enrichment	ALPL	2.14
46	Osteoporosis, juvenile	Enrichment	DKK1	2.14
47	Neurodevelopmental disorder with spastic diplegia and visual defects	Enrichment	CTNNB1	2.14
48	Anus, imperforate	Enrichment	CTNNB1	2.14
49	Exudative vitreoretinopathy 7	Enrichment	CTNNB1	2.14
50	Keratoderma-ichthyosis-deafness syndrome, autosomal recessive	Enrichment	HNF1A	2.14
51	Desmoid tumor	Enrichment	CTNNB1	2.14
52	Chromophobe renal cell carcinoma	Enrichment	HNF1A	2.14
53	Cleidocranial dysplasia	Enrichment	RUNX2	2.14
54	Migraine without aura	Enrichment	NOTCH3	2.14
55	Maturity-onset diabetes of the young, type 3	Enrichment	HNF1A	2.01
56	Pilomatrixoma	Enrichment	CTNNB1	2.01
57	Dentin dysplasia, type i	Enrichment	DSPP	2.01
58	Alazami syndrome	Enrichment	CTNNB1	2.01
59	Cerebrovascular disease	Enrichment	NOTCH3	2.01
60	Craniopharyngioma	Enrichment	CTNNB1	2.01
61	Clear cell papillary renal cell carcinoma	Enrichment	HNF1A	2.01
62	Cerebral arteriopathy, autosomal dominant, with subcortical infarcts and leukoencephalopathy, type 1	Enrichment	NOTCH3	1.92
63	Exudative vitreoretinopathy 1	Enrichment	CTNNB1	1.92
64	Ventricular septal defect 1	Enrichment	BMP7	1.92
65	Congenital heart defects, multiple types, 4	Enrichment	BMP7	1.92
66	Vascular dementia	Enrichment	NOTCH3	1.92
67	Weyers acrofacial dysostosis	Enrichment	CTNNB1	1.84
68	Type 1 diabetes mellitus	Enrichment	HNF1A	1.84
69	Adrenocortical carcinoma	Enrichment	CTNNB1	1.84
70	Clear cell renal cell carcinoma	Enrichment	HNF1A	1.84
71	Adams-oliver syndrome	Enrichment	NOTCH1	1.77
72	Gallbladder cancer	Enrichment	CTNNB1	1.77
73	Hypophosphatemic rickets	Enrichment	DMP1	1.77
74	Exudative vitreoretinopathy	Enrichment	CTNNB1	1.71
75	Hypoplastic left heart syndrome	Enrichment	NOTCH1	1.71
76	Adult hepatocellular carcinoma	Enrichment	CTNNB1	1.66
77	Stroke, ischemic	Enrichment	NOTCH3	1.62
78	Ovarian cancer	Enrichment	CTNNB1, HNF1A	1.60
79	Migraine with or without aura 1	Enrichment	NOTCH3	1.58
80	Diabetes mellitus	Enrichment	HNF1A	1.58
81	Digeorge syndrome	Enrichment	HNF1A	1.54
82	Aortic valve disease 1	Enrichment	NOTCH1	1.51
83	Osteogenesis imperfecta, type iv	Enrichment	SP7	1.51
84	Medulloblastoma	Enrichment	CTNNB1	1.47
85	Aortic aneurysm, familial thoracic 1	Enrichment	NOTCH1	1.47
86	Renal cell carcinoma, nonpapillary	Enrichment	HNF1A	1.44
87	Polycystic liver disease	Enrichment	CTNNB1	1.39
88	Autosomal dominant polycystic liver disease	Enrichment	CTNNB1	1.39
89	Maturity-onset diabetes of the young	Enrichment	HNF1A	1.32
90	Hepatoblastoma	Enrichment	CTNNB1	1.30
91	Hepatocellular carcinoma	Enrichment	CTNNB1	1.28
92	Brittle bone disorder	Enrichment	ALPL	1.26
93	Tetralogy of fallot	Enrichment	NOTCH1	1.21
94	Auditory neuropathy	Enrichment	NOTCH3	1.21
95	Bladder cancer	Enrichment	CTNNB1	1.17
96	Connective tissue disease	Enrichment	NOTCH1	1.12
97	Type 2 diabetes mellitus	Enrichment	HNF1A	1.01
98	Nephrotic syndrome	Enrichment	RUNX2	1.00
99	Familial thoracic aortic aneurysm and aortic dissection	Enrichment	NOTCH1	0.99
100	Primary ovarian insufficiency	Enrichment	NOTCH2	0.87
101	Breast cancer	Enrichment	HNF1A	0.78
102	Colorectal cancer	Enrichment	CTNNB1	0.72
103	Congenital nervous system abnormality	Enrichment	CTNNB1	0.64
104	Nervous system disease	Enrichment	CTNNB1	0.64
105	Microcephaly	Enrichment	CTNNB1	0.59

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

OSX and miRNAs in tooth development

Pathway Network for OSX and miRNAs in tooth development

Member Pathways for OSX and miRNAs in tooth development

Pathways in the OSX and miRNAs in tooth development SuperPath

Associated Genes for OSX and miRNAs in tooth development

Associated Disorders for OSX and miRNAs in tooth development

Disorders associated with OSX and miRNAs in tooth development SuperPath

STRING Interaction Network for OSX and miRNAs in tooth development

Sources for OSX and miRNAs in tooth development