Overview of nanoparticle effects

No Pathway Network information available for Overview of nanoparticle effects

Pathways in the Overview of nanoparticle effects SuperPath

#	Name	Source	Genes
1	Overview of nanoparticle effects	WikiPathways	AKT3 BAX BCL2 CCND3 CDH3 COL4A1 CRP CXCL8 FN1 HMOX1 IL6 ITGAD LAMA3 NFRKB PIK3CD PTGS1 PTGS2 PTK2 TNF (see all 19) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	CCND3	Cyclin D3	Protein Coding	1
2	TNF	Tumor Necrosis Factor	Protein Coding	1
3	BCL2	BCL2 Apoptosis Regulator	Protein Coding	1
4	BAX	BCL2 Associated X, Apoptosis Regulator	Protein Coding	1
5	PTK2	Protein Tyrosine Kinase 2	Protein Coding	1
6	PTGS2	Prostaglandin-Endoperoxide Synthase 2	Protein Coding	1
7	PTGS1	Prostaglandin-Endoperoxide Synthase 1	Protein Coding	1
8	PIK3CD	Phosphatidylinositol-4,5-Bisphosphate 3-Kinase Catalytic Subunit Delta	Protein Coding	1
9	LAMA3	Laminin Subunit Alpha 3	Protein Coding	1
10	CXCL8	C-X-C Motif Chemokine Ligand 8	Protein Coding	1
11	IL6	Interleukin 6	Protein Coding	1
12	HMOX1	Heme Oxygenase 1	Protein Coding	1
13	FN1	Fibronectin 1	Protein Coding	1
14	CRP	C-Reactive Protein	Protein Coding	1
15	COL4A1	Collagen Type IV Alpha 1 Chain	Protein Coding	1
16	CDH3	Cadherin 3	Protein Coding	1
17	AKT3	AKT Serine/Threonine Kinase 3	Protein Coding	1
18	NFRKB	Nuclear Factor Related To KappaB Binding Protein	Protein Coding	1
19	ITGAD	Integrin Subunit Alpha D	Protein Coding	1

Disorders associated with Overview of nanoparticle effects SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Ectodermal dysplasia, ectrodactyly, and macular dystrophy syndrome	Enrichment	CDH3	2.85
2	Porencephaly	Enrichment	COL4A1	2.85
3	Megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome 2	Enrichment	AKT3	2.85
4	Hypotrichosis	Enrichment	CDH3	2.85
5	Immunodeficiency 14b, autosomal recessive	Enrichment	PIK3CD	2.85
6	Heme oxygenase 1 deficiency	Enrichment	HMOX1	2.85
7	Col4a1-related disorders	Enrichment	COL4A1	2.85
8	Capillary hemangioma	Enrichment	AKT3	2.85
9	Col4a1 or col4a2-related cerebral small vessel disease	Enrichment	COL4A1	2.85
10	Spondyloepimetaphyseal dysplasia, strudwick type	Enrichment	FN1	2.55
11	Spondylometaphyseal dysplasia, corner fracture type	Enrichment	FN1	2.55
12	Epidermolysis bullosa, junctional 2c, laryngoonychocutaneous	Enrichment	LAMA3	2.55
13	Hypotrichosis, congenital, with juvenile macular dystrophy	Enrichment	CDH3	2.55
14	Roifman-chitayat syndrome	Enrichment	PIK3CD	2.55
15	Epidermolysis bullosa, junctional 2a, intermediate	Enrichment	LAMA3	2.55
16	Intravascular large b-cell lymphoma	Enrichment	BCL2	2.55
17	Immunodeficiency 127	Enrichment	TNF	2.55
18	Senior-loken syndrome 7	Enrichment	AKT3	2.55
19	Immune system disease	Enrichment	PIK3CD	2.55
20	Bardet-biedl syndrome 16	Enrichment	AKT3	2.55
21	Epidermolysis bullosa, junctional 2b, severe	Enrichment	LAMA3	2.55
22	Retinal arteries, tortuosity of	Enrichment	COL4A1	2.38
23	Glomerulopathy with fibronectin deposits 2	Enrichment	FN1	2.38
24	Psoriatic arthritis	Enrichment	TNF	2.38
25	Immunodeficiency 14a with lymphoproliferation, autosomal dominant	Enrichment	PIK3CD	2.38
26	Microangiopathy and leukoencephalopathy, pontine, autosomal dominant	Enrichment	COL4A1	2.38
27	High-grade b-cell lymphoma double-hit/triple-hit	Enrichment	BCL2	2.38
28	Angiopathy, hereditary, with nephropathy, aneurysms, and muscle cramps	Enrichment	COL4A1	2.38
29	Immunodeficiency 14	Enrichment	PIK3CD	2.38
30	T-cell acute lymphoblastic leukemia	Enrichment	BAX	2.38
31	Migraine without aura	Enrichment	TNF	2.38
32	Kaposi sarcoma	Enrichment	IL6	2.25
33	Brain small vessel disease 1 with or without ocular anomalies	Enrichment	COL4A1	2.25
34	Schizencephaly	Enrichment	COL4A1	2.25
35	Megalencephaly-capillary malformation-polymicrogyria syndrome	Enrichment	AKT3	2.25
36	Megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome 1	Enrichment	AKT3	2.25
37	Cerebral malaria	Enrichment	TNF	2.25
38	Systemic-onset juvenile idiopathic arthritis	Enrichment	IL6	2.25
39	Rheumatoid arthritis, systemic juvenile	Enrichment	IL6	2.16
40	Follicular lymphoma	Enrichment	BCL2	2.16
41	Vascular dementia	Enrichment	TNF	2.16
42	Hemimegalencephaly	Enrichment	AKT3	2.16
43	Familial porencephaly	Enrichment	COL4A1	2.16
44	Epidermolysis bullosa, junctional 1a, intermediate	Enrichment	LAMA3	2.08
45	Epidermolysis bullosa, junctional 1b, severe	Enrichment	LAMA3	2.08
46	Type 1 diabetes mellitus	Enrichment	IL6	2.08
47	Anterior segment dysgenesis 5	Enrichment	COL4A1	2.08
48	Hemorrhage, intracerebral	Enrichment	COL4A1	2.08
49	Junctional epidermolysis bullosa non-herlitz type	Enrichment	LAMA3	2.08
50	Keratoconus	Enrichment	COL4A1	2.08
51	Megacolon	Enrichment	AKT3	2.01
52	Inflammatory bowel disease 1	Enrichment	IL6	1.90
53	Junctional epidermolysis bullosa	Enrichment	LAMA3	1.90
54	Hypotrichosis simplex	Enrichment	CDH3	1.90
55	Peters-plus syndrome	Enrichment	COL4A1	1.86
56	Polymicrogyria	Enrichment	AKT3	1.86
57	Autosomal non-syndromic agammaglobulinemia	Enrichment	PIK3CD	1.86
58	Asthma	Enrichment	TNF	1.82
59	Pulmonary disease, chronic obstructive	Enrichment	HMOX1	1.74
60	Alzheimer's disease	Enrichment	TNF	1.74
61	Walker-warburg syndrome	Enrichment	COL4A1	1.71
62	Corpus callosum, agenesis of	Enrichment	COL4A1	1.68
63	Anterior segment dysgenesis	Enrichment	COL4A1	1.68
64	Isolated corpus callosum agenesis	Enrichment	COL4A1	1.68
65	Intellectual disability-hypoplastic corpus callosum-preauricular tag syndrome	Enrichment	COL4A1	1.68
66	Arteriovenous malformations of the brain	Enrichment	IL6	1.58
67	Malaria	Enrichment	TNF	1.50
68	Cystic fibrosis	Enrichment	HMOX1	1.36
69	Cakut	Enrichment	COL4A1	1.33
70	Systemic lupus erythematosus	Enrichment	TNF	1.27
71	Cerebral palsy	Enrichment	COL4A1	1.27
72	Type 2 diabetes mellitus	Enrichment	IL6	1.24
73	Nephrotic syndrome	Enrichment	FN1	1.23
74	Colorectal cancer	Enrichment	BAX	0.94
75	Microcephaly	Enrichment	COL4A1	0.80
76	Retinitis pigmentosa	Enrichment	CDH3	0.59
77	Hereditary retinal dystrophy	Enrichment	CDH3	0.47
78	Fundus dystrophy	Enrichment	CDH3	0.47

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Overview of nanoparticle effects

Pathway Network for Overview of nanoparticle effects

Member Pathways for Overview of nanoparticle effects

Pathways in the Overview of nanoparticle effects SuperPath

Associated Genes for Overview of nanoparticle effects

Associated Disorders for Overview of nanoparticle effects

Disorders associated with Overview of nanoparticle effects SuperPath

STRING Interaction Network for Overview of nanoparticle effects

Sources for Overview of nanoparticle effects