Oxysterols derived from cholesterol

No Pathway Network information available for Oxysterols derived from cholesterol

Pathways in the Oxysterols derived from cholesterol SuperPath

#	Name	Source	Genes
1	Oxysterols derived from cholesterol	WikiPathways	ACOT1 ACOT11 ACOT12 ACOT13 ACOT2 ACOT4 ACOT6 ACOT7 ACOT8 ACOT9 CH25H CYP27A1 CYP3A4 CYP46A1 CYP7A1 CYP7B1 DHCR7 EBP EPHX2 ESR1 ESR2 GPR183 HSD11B1 HSD11B2 HSD3B7 IL17A IL17B IL17C IL17D IL17F IL25 INSIG1 NR1H2 NR1I2 THEM5 (see all 35) (see less)
2	7-oxo-C and 7-beta-HC pathways	WikiPathways	ACOT1 ACOT11 ACOT12 ACOT13 ACOT2 ACOT4 ACOT6 ACOT7 ACOT8 ACOT9 BAAT DHCR7 EBP EPHX2 THEM5 (see all 15) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	ACOT11	Acyl-CoA Thioesterase 11	Protein Coding	2
2	ACOT6	Acyl-CoA Thioesterase 6	Protein Coding	2
3	THEM5	Thioesterase Superfamily Member 5	Protein Coding	2
4	ACOT9	Acyl-CoA Thioesterase 9	Protein Coding	2
5	ACOT13	Acyl-CoA Thioesterase 13	Protein Coding	2
6	ACOT7	Acyl-CoA Thioesterase 7	Protein Coding	2
7	ACOT4	Acyl-CoA Thioesterase 4	Protein Coding	2
8	ACOT1	Acyl-CoA Thioesterase 1	Protein Coding	2
9	ACOT2	Acyl-CoA Thioesterase 2	Protein Coding	2
10	ACOT12	Acyl-CoA Thioesterase 12	Protein Coding	2
11	DHCR7	7-Dehydrocholesterol Reductase	Protein Coding	2
12	EBP	EBP Cholestenol Delta-Isomerase	Protein Coding	2
13	ACOT8	Acyl-CoA Thioesterase 8	Protein Coding	2
14	EPHX2	Epoxide Hydrolase 2	Protein Coding	2
15	IL17B	Interleukin 17B	Protein Coding	1
16	IL17D	Interleukin 17D	Protein Coding	1
17	INSIG1	Insulin Induced Gene 1	Protein Coding	1
18	CYP7B1	Cytochrome P450 Family 7 Subfamily B Member 1	Protein Coding	1
19	HSD11B2	Hydroxysteroid 11-Beta Dehydrogenase 2	Protein Coding	1
20	IL25	Interleukin 25	Protein Coding	1
21	IL17C	Interleukin 17C	Protein Coding	1
22	IL17A	Interleukin 17A	Protein Coding	1
23	IL17F	Interleukin 17F	Protein Coding	1
24	NR1H2	Nuclear Receptor Subfamily 1 Group H Member 2	Protein Coding	1
25	ESR2	Estrogen Receptor 2	Protein Coding	1
26	GPR183	G Protein-Coupled Receptor 183	Protein Coding	1
27	CH25H	Cholesterol 25-Hydroxylase	Protein Coding	1
28	HSD3B7	Hydroxy-Delta-5-Steroid Dehydrogenase, 3 Beta- And Steroid Delta-Isomerase 7	Protein Coding	1
29	CYP27A1	Cytochrome P450 Family 27 Subfamily A Member 1	Protein Coding	1
30	CYP46A1	Cytochrome P450 Family 46 Subfamily A Member 1	Protein Coding	1
31	HSD11B1	Hydroxysteroid 11-Beta Dehydrogenase 1	Protein Coding	1
32	CYP7A1	Cytochrome P450 Family 7 Subfamily A Member 1	Protein Coding	1
33	NR1I2	Nuclear Receptor Subfamily 1 Group I Member 2	Protein Coding	1
34	ESR1	Estrogen Receptor 1	Protein Coding	1
35	CYP3A4	Cytochrome P450 Family 3 Subfamily A Member 4	Protein Coding	1
36	BAAT	Bile Acid-CoA:Amino Acid N-Acyltransferase	Protein Coding	1

Disorders associated with Oxysterols derived from cholesterol SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Chondrodysplasia punctata 2, x-linked dominant	Enrichment	EBP	2.96
2	Mend syndrome	Enrichment	EBP	2.96
3	Hypercholanemia, familial 3	Enrichment	BAAT	2.96
4	Apparent mineralocorticoid excess	Enrichment	HSD11B2	2.59
5	Bile acid synthesis defect, congenital, 3	Enrichment	CYP7B1	2.59
6	Candidiasis, familial, 6	Enrichment	IL17F	2.59
7	Cerebrotendinous xanthomatosis	Enrichment	CYP27A1	2.59
8	Ovarian dysgenesis 8	Enrichment	ESR2	2.59
9	Bile acid synthesis defect, congenital, 1	Enrichment	HSD3B7	2.59
10	Vitamin d-dependent rickets, type 3	Enrichment	CYP3A4	2.59
11	Hypercholesterolemia due to cholesterol 7alpha-hydroxylase deficiency	Enrichment	CYP7A1	2.59
12	Smith-lemli-opitz syndrome	Enrichment	DHCR7	2.35
13	Congenital bile acid synthesis defect	Enrichment	HSD3B7	2.29
14	Spastic paraplegia 5a, autosomal recessive	Enrichment	CYP7B1	2.29
15	Cortisone reductase deficiency 2	Enrichment	HSD11B1	2.29
16	Cortisone reductase deficiency	Enrichment	HSD11B1	2.29
17	Familial hypercholanemia	Enrichment	BAAT	2.18
18	Thyroid carcinoma, familial medullary	Enrichment	ESR2	2.11
19	Estrogen resistance	Enrichment	ESR1	2.11
20	Migraine without aura	Enrichment	ESR1	2.11
21	Arthrogryposis multiplex congenita 3, myogenic type	Enrichment	ESR1	1.99
22	Hypercholesterolemia, familial, 1	Enrichment	EPHX2	1.85
23	Chronic mucocutaneous candidiasis	Enrichment	IL17F	1.81
24	Familial hypercholesterolemia	Enrichment	EPHX2	1.78
25	Isolated congenital microcephaly	Enrichment	DHCR7	1.76
26	Hepatoblastoma	Enrichment	DHCR7	1.64
27	Migraine with or without aura 1	Enrichment	ESR1	1.55
28	Pulmonary disease, chronic obstructive	Enrichment	CYP46A1	1.48
29	Connective tissue disease	Enrichment	EBP	1.46
30	Myocardial infarction	Enrichment	ESR1	1.26
31	Hereditary spastic paraplegia	Enrichment	CYP7B1	0.99
32	Hereditary breast carcinoma	Enrichment	ESR1	0.97
33	Spastic ataxia	Enrichment	CYP7B1	0.89
34	Breast cancer	Enrichment	ESR1	0.75

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Oxysterols derived from cholesterol

Pathway Network for Oxysterols derived from cholesterol

Member Pathways for Oxysterols derived from cholesterol

Pathways in the Oxysterols derived from cholesterol SuperPath

Associated Genes for Oxysterols derived from cholesterol

Associated Disorders for Oxysterols derived from cholesterol

Disorders associated with Oxysterols derived from cholesterol SuperPath

STRING Interaction Network for Oxysterols derived from cholesterol

Sources for Oxysterols derived from cholesterol