p38 signaling mediated by MAPKAP kinases

No Pathway Network information available for p38 signaling mediated by MAPKAP kinases

Pathways in the p38 signaling mediated by MAPKAP kinases SuperPath

#	Name	Source	Genes
1	p38 signaling mediated by MAPKAP kinases	PubChem	CDC25B CREB1 ETV1 HSPB1 LSP1 MAPK14 MAPKAPK2 MAPKAPK3 RAF1 SFN SRF TCF3 TH TSC2 YWHAZ (see all 15) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	LSP1	Lymphocyte Specific Protein 1	Protein Coding	1
2	ETV1	ETS Variant Transcription Factor 1	Protein Coding	1
3	CREB1	CAMP Responsive Element Binding Protein 1	Protein Coding	1
4	CDC25B	Cell Division Cycle 25B	Protein Coding	1
5	MAPKAPK3	MAPK Activated Protein Kinase 3	Protein Coding	1
6	SRF	Serum Response Factor	Protein Coding	1
7	HSPB1	Heat Shock Protein Family B (Small) Member 1	Protein Coding	1
8	TH	Tyrosine Hydroxylase	Protein Coding	1
9	MAPKAPK2	MAPK Activated Protein Kinase 2	Protein Coding	1
10	MAPK14	Mitogen-Activated Protein Kinase 14	Protein Coding	1
11	TCF3	Transcription Factor 3	Protein Coding	1
12	TSC2	TSC Complex Subunit 2	Protein Coding	1
13	SFN	Stratifin	Protein Coding	1
14	YWHAZ	Tyrosine 3-Monooxygenase/Tryptophan 5-Monooxygenase Activation Protein Zeta	Protein Coding	1
15	RAF1	Raf-1 Proto-Oncogene, Serine/Threonine Kinase	Protein Coding	1

Disorders associated with p38 signaling mediated by MAPKAP kinases SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Noonan syndrome 5	Enrichment	RAF1	2.96
2	Cardiomyopathy, dilated, 1nn	Enrichment	RAF1	2.96
3	Agammaglobulinemia 8b, autosomal recessive	Enrichment	TCF3	2.96
4	Agammaglobulinemia 8a, autosomal dominant	Enrichment	TCF3	2.96
5	Charcot-marie-tooth disease, axonal, type 2f	Enrichment	HSPB1	2.96
6	Leopard syndrome 2	Enrichment	RAF1	2.96
7	Macular dystrophy, patterned, 3	Enrichment	MAPKAPK3	2.96
8	Trigonitis	Enrichment	RAF1	2.96
9	Histiocytoma, angiomatoid fibrous	Enrichment	CREB1	2.66
10	Lymphangioleiomyomatosis	Enrichment	TSC2	2.66
11	Segawa syndrome, autosomal recessive	Enrichment	TH	2.66
12	Neuronopathy, distal hereditary motor, autosomal dominant 3	Enrichment	HSPB1	2.66
13	B-lymphoblastic leukemia/lymphoma with t(1;19)(q23;p13.3)	Enrichment	TCF3	2.66
14	B-lymphoblastic leukemia/lymphoma with t(17;19)	Enrichment	TCF3	2.66
15	Dystonia, dopa-responsive	Enrichment	TH	2.48
16	Tuberous sclerosis 1	Enrichment	TSC2	2.48
17	Polycystic kidney disease, infantile severe, with tuberous sclerosis	Enrichment	TSC2	2.48
18	Tuberous sclerosis 2	Enrichment	TSC2	2.48
19	Bacteremia 2	Enrichment	MAPKAPK3	2.48
20	Hamartoma	Enrichment	TSC2	2.48
21	Xanthinuria, type ii	Enrichment	TSC2	2.48
22	Melanoma of soft tissue	Enrichment	CREB1	2.48
23	Focal cortical dysplasia, type ii	Enrichment	TSC2	2.35
24	Tuberous sclerosis	Enrichment	TSC2	2.35
25	Tuberculosis	Enrichment	MAPKAPK3	2.35
26	Noonan syndrome-like disorder with or without juvenile myelomonocytic leukemia	Enrichment	YWHAZ	2.35
27	Noonan syndrome with multiple lentigines	Enrichment	RAF1	2.35
28	Isolated focal cortical dysplasia type ii	Enrichment	TSC2	2.35
29	Neuronopathy, distal hereditary motor, autosomal dominant 2	Enrichment	HSPB1	2.26
30	Polycystic kidney disease 1 with or without polycystic liver disease	Enrichment	TSC2	2.11
31	Noonan syndrome 3	Enrichment	RAF1	2.11
32	Polycystic kidney disease 1	Enrichment	TSC2	2.11
33	Pilomyxoid astrocytoma	Enrichment	RAF1	2.11
34	Melanocytic nevus syndrome, congenital	Enrichment	RAF1	2.05
35	Ewing sarcoma	Enrichment	ETV1	2.05
36	Adult hepatocellular carcinoma	Enrichment	TSC2	2.00
37	Autosomal non-syndromic agammaglobulinemia	Enrichment	TCF3	1.96
38	Autosomal dominant polycystic kidney disease	Enrichment	TSC2	1.78
39	Noonan syndrome and noonan-related syndrome	Enrichment	RAF1	1.78
40	Noonan syndrome 1	Enrichment	RAF1	1.60
41	Malaria	Enrichment	MAPKAPK3	1.60
42	Cardiomyopathy, familial hypertrophic, 1	Enrichment	RAF1	1.58
43	Rasopathy	Enrichment	RAF1	1.55
44	Familial hypertrophic cardiomyopathy	Enrichment	RAF1	1.44
45	Left ventricular noncompaction	Enrichment	RAF1	1.42
46	Dystonia	Enrichment	TH	1.42
47	Charcot-marie-tooth disease	Enrichment	HSPB1	1.35
48	West syndrome	Enrichment	TSC2	1.32
49	Autosomal dominant non-syndromic intellectual disability	Enrichment	YWHAZ	1.27
50	Familial isolated dilated cardiomyopathy	Enrichment	RAF1	1.24
51	Myeloma, multiple	Enrichment	TCF3	1.22
52	Dilated cardiomyopathy	Enrichment	RAF1	1.07
53	Ovarian cancer	Enrichment	TSC2	0.97
54	Congenital nervous system abnormality	Enrichment	TSC2	0.95
55	Nervous system disease	Enrichment	TSC2	0.95
56	Autism spectrum disorder	Enrichment	TSC2	0.94
57	Inherited cancer-predisposing syndrome	Enrichment	TSC2	0.86

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

p38 signaling mediated by MAPKAP kinases

Pathway Network for p38 signaling mediated by MAPKAP kinases

Member Pathways for p38 signaling mediated by MAPKAP kinases

Pathways in the p38 signaling mediated by MAPKAP kinases SuperPath

Associated Genes for p38 signaling mediated by MAPKAP kinases

Associated Disorders for p38 signaling mediated by MAPKAP kinases

Disorders associated with p38 signaling mediated by MAPKAP kinases SuperPath

STRING Interaction Network for p38 signaling mediated by MAPKAP kinases

Sources for p38 signaling mediated by MAPKAP kinases