p53 transcriptional gene network

No Pathway Network information available for p53 transcriptional gene network

Pathways in the p53 transcriptional gene network SuperPath

#	Name	Source	Genes
1	p53 transcriptional gene network	WikiPathways	ACAD11 ADGRB1 ADORA2B AKT1S1 ALDH4A1 APAF1 AURKA BAX BBC3 BTG2 CCL2 CCNE1 CCNG1 CDC25C CDK2 CDKN1A CPT1C CX3CL1 DDB2 DDIT4 DEPTOR DRAM1 E2F7 ERCC5 FAS FASLG FUCA1 GADD45A GLS2 GPX1 ICAM1 IRF5 IRF9 ISG15 LIF LOC105376156 MGMT MIR145 MIR200C MIR34A MIR34B MIR34C MLH1 MLST8 MSH2 MTOR NANOG NCF2 NOTCH1 PCNA PERP PIDD1 PMAIP1 PML POLH POLK PRKAA1 PRKAA2 PRKAB1 PRKAB2 PRKAG1 PRKAG2 PRKAG3 PTEN RPRM RPTOR RRM2B SAT1 SCO2 SERPINB5 SERPINE1 SESN1 SESN2 SFN SIVA1 SLC2A1 SLC7A11 SMR3B THBS1 TIGAR TNF TNFRSF10B TNFRSF10D TP53AIP1 TP53I3 TP53INP1 TRAF4 TSC2 ULBP1 ULBP2 ULK1 ULK2 XPC XRCC5 ZMAT3 (see all 95) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	ULBP1	UL16 Binding Protein 1	Protein Coding	1
2	SCO2	Synthesis Of Cytochrome C Oxidase 2	Protein Coding	1
3	CDC25C	Cell Division Cycle 25C	Protein Coding	1
4	ULK2	Unc-51 Like Autophagy Activating Kinase 2	Protein Coding	1
5	ISG15	ISG15 Ubiquitin Like Modifier	Protein Coding	1
6	TRAF4	TNF Receptor Associated Factor 4	Protein Coding	1
7	TP53I3	Tumor Protein P53 Inducible Protein 3	Protein Coding	1
8	CCNG1	Cyclin G1	Protein Coding	1
9	CCNE1	Cyclin E1	Protein Coding	1
10	TNFRSF10B	TNF Receptor Superfamily Member 10b	Protein Coding	1
11	ALDH4A1	Aldehyde Dehydrogenase 4 Family Member A1	Protein Coding	1
12	AKT1S1	AKT1 Substrate 1	Protein Coding	1
13	SESN2	Sestrin 2	Protein Coding	1
14	ULBP2	UL16 Binding Protein 2	Protein Coding	1
15	NANOG	Nanog Homeobox	Protein Coding	1
16	BTG2	BTG Anti-Proliferation Factor 2	Protein Coding	1
17	XRCC5	X-Ray Repair Cross Complementing 5	Protein Coding	1
18	XPC	XPC Complex Subunit, DNA Damage Recognition And Repair Factor	Protein Coding	1
19	TSC2	TSC Complex Subunit 2	Protein Coding	1
20	TNF	Tumor Necrosis Factor	Protein Coding	1
21	THBS1	Thrombospondin 1	Protein Coding	1
22	AURKA	Aurora Kinase A	Protein Coding	1
23	SLC2A1	Solute Carrier Family 2 Member 1	Protein Coding	1
24	ZMAT3	Zinc Finger Matrin-Type 3	Protein Coding	1
25	CX3CL1	C-X3-C Motif Chemokine Ligand 1	Protein Coding	1
26	CCL2	C-C Motif Chemokine Ligand 2	Protein Coding	1
27	SAT1	Spermidine/Spermine N1-Acetyltransferase 1	Protein Coding	1
28	BAX	BCL2 Associated X, Apoptosis Regulator	Protein Coding	1
29	RPTOR	Regulatory Associated Protein Of MTOR Complex 1	Protein Coding	1
30	PTEN	Phosphatase And Tensin Homolog	Protein Coding	1
31	TIGAR	TP53 Induced Glycolysis Regulatory Phosphatase	Protein Coding	1
32	RPRM	Reprimo, TP53 Dependent G2 Arrest Mediator Homolog	Protein Coding	1
33	PRKAB1	Protein Kinase AMP-Activated Non-Catalytic Subunit Beta 1	Protein Coding	1
34	PRKAA2	Protein Kinase AMP-Activated Catalytic Subunit Alpha 2	Protein Coding	1
35	PRKAA1	Protein Kinase AMP-Activated Catalytic Subunit Alpha 1	Protein Coding	1
36	PIDD1	P53-Induced Death Domain Protein 1	Protein Coding	1
37	DRAM1	DNA Damage Regulated Autophagy Modulator 1	Protein Coding	1
38	DDIT4	DNA Damage Inducible Transcript 4	Protein Coding	1
39	POLH	DNA Polymerase Eta	Protein Coding	1
40	PML	PML Nuclear Body Scaffold	Protein Coding	1
41	PMAIP1	Phorbol-12-Myristate-13-Acetate-Induced Protein 1	Protein Coding	1
42	PRKAG3	Protein Kinase AMP-Activated Non-Catalytic Subunit Gamma 3	Protein Coding	1
43	SERPINB5	Serpin Family B Member 5	Protein Coding	1
44	POLK	DNA Polymerase Kappa	Protein Coding	1
45	PRKAG2	Protein Kinase AMP-Activated Non-Catalytic Subunit Gamma 2	Protein Coding	1
46	PCNA	Proliferating Cell Nuclear Antigen	Protein Coding	1
47	SERPINE1	Serpin Family E Member 1	Protein Coding	1
48	RRM2B	Ribonucleotide Reductase Regulatory TP53 Inducible Subunit M2B	Protein Coding	1
49	NOTCH1	Notch Receptor 1	Protein Coding	1
50	NCF2	Neutrophil Cytosolic Factor 2	Protein Coding	1
51	MSH2	MutS Homolog 2	Protein Coding	1
52	MLH1	MutL Homolog 1	Protein Coding	1
53	MGMT	O-6-Methylguanine-DNA Methyltransferase	Protein Coding	1
54	MIR34C	MicroRNA 34c	RNA Gene	1
55	MIR34B	MicroRNA 34b	RNA Gene	1
56	MIR34A	MicroRNA 34a	RNA Gene	1
57	MIR200C	MicroRNA 200c	RNA Gene	1
58	MIR145	MicroRNA 145	RNA Gene	1
59	LIF	LIF Interleukin 6 Family Cytokine	Protein Coding	1
60	IRF5	Interferon Regulatory Factor 5	Protein Coding	1
61	FASLG	Fas Ligand	Protein Coding	1
62	FAS	Fas Cell Surface Death Receptor	Protein Coding	1
63	ICAM1	Intercellular Adhesion Molecule 1	Protein Coding	1
64	APAF1	Apoptotic Peptidase Activating Factor 1	Protein Coding	1
65	GPX1	Glutathione Peroxidase 1	Protein Coding	1
66	SFN	Stratifin	Protein Coding	1
67	GLS2	Glutaminase 2	Protein Coding	1
68	BBC3	BCL2 Binding Component 3	Protein Coding	1
69	FUCA1	Alpha-L-Fucosidase 1	Protein Coding	1
70	MTOR	Mechanistic Target Of Rapamycin Kinase	Protein Coding	1
71	SLC7A11	Solute Carrier Family 7 Member 11	Protein Coding	1
72	ERCC5	ERCC Excision Repair 5, Endonuclease	Protein Coding	1
73	GADD45A	Growth Arrest And DNA Damage Inducible Alpha	Protein Coding	1
74	DDB2	Damage Specific DNA Binding Protein 2	Protein Coding	1
75	E2F7	E2F Transcription Factor 7	Protein Coding	1
76	ADORA2B	Adenosine A2b Receptor	Protein Coding	1
77	CPT1C	Carnitine Palmitoyltransferase 1C	Protein Coding	1
78	SIVA1	SIVA1 Apoptosis Inducing Factor	Protein Coding	1
79	CDKN1A	Cyclin Dependent Kinase Inhibitor 1A	Protein Coding	1
80	CDK2	Cyclin Dependent Kinase 2	Protein Coding	1
81	TP53INP1	Tumor Protein P53 Inducible Nuclear Protein 1	Protein Coding	1
82	TNFRSF10D	TNF Receptor Superfamily Member 10d	Protein Coding	1
83	ACAD11	Acyl-CoA Dehydrogenase Family Member 11	Protein Coding	1
84	ULK1	Unc-51 Like Autophagy Activating Kinase 1	Protein Coding	1
85	SMR3B	Submaxillary Gland Androgen Regulated Protein 3B	Protein Coding	1
86	LOC105376156	Uncharacterized LOC105376156	RNA Gene	1
87	IRF9	Interferon Regulatory Factor 9	Protein Coding	1
88	DEPTOR	DEP Domain Containing MTOR Interacting Protein	Protein Coding	1
89	MLST8	MTOR Associated Protein MLST8	Protein Coding	1
90	PERP	P53 Apoptosis Effector Related To PMP22	Protein Coding	1
91	TP53AIP1	Tumor Protein P53 Regulated Apoptosis Inducing Protein 1	Protein Coding	1
92	ADGRB1	Adhesion G Protein-Coupled Receptor B1	Protein Coding	1
93	PRKAG1	Protein Kinase AMP-Activated Non-Catalytic Subunit Gamma 1	Protein Coding	1
94	PRKAB2	Protein Kinase AMP-Activated Non-Catalytic Subunit Beta 2	Protein Coding	1
95	SESN1	Sestrin 1	Protein Coding	1

Disorders associated with p53 transcriptional gene network SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Xeroderma pigmentosum, variant type	Enrichment	DDB2, ERCC5, POLH, XPC	6.14
2	Muir-torre syndrome	Enrichment	MLH1, MSH2	4.31
3	Laryngeal squamous cell carcinoma	Enrichment	PTEN, TNFRSF10B	3.84
4	Mismatch repair cancer syndrome 1	Enrichment	MLH1, MSH2	3.54
5	Autoimmune lymphoproliferative syndrome	Enrichment	FAS, FASLG	3.54
6	Focal cortical dysplasia, type ii	Enrichment	MTOR, TSC2	3.54
7	Cerebral malaria	Enrichment	ICAM1, TNF	3.54
8	Isolated focal cortical dysplasia type ii	Enrichment	MTOR, TSC2	3.54
9	Endometrial cancer	Enrichment	MLH1, MSH2, PTEN	3.39
10	Hemimegalencephaly	Enrichment	MTOR, PTEN	3.32
11	Ovarian cancer	Enrichment	ERCC5, MSH2, PTEN, TSC2, XPC	3.15
12	Squamous cell carcinoma, head and neck	Enrichment	PTEN, TNFRSF10B	3.00
13	Lung cancer	Enrichment	FAS, FASLG, MLH1	2.85
14	Mitochondrial neurogastrointestinal encephalomyopathy	Enrichment	RRM2B, SCO2	2.77
15	Lynch syndrome 1	Enrichment	MLH1, MSH2	2.68
16	Familial colorectal cancer	Enrichment	MLH1, MSH2	2.68
17	Uterine corpus cancer	Enrichment	MSH2, PTEN	2.59
18	Colorectal cancer	Enrichment	AURKA, BAX, MLH1, MSH2	2.49
19	Gastric cancer	Enrichment	MLH1, MSH2, PTEN	2.47
20	Hereditary breast carcinoma	Enrichment	MLH1, MSH2, PTEN	2.45
21	Lynch syndrome	Enrichment	MLH1, MSH2	2.32
22	Rhabdomyosarcoma	Enrichment	MSH2, PTEN	2.26
23	Gliosarcoma	Enrichment	MGMT, MSH2	2.26
24	Giant cell glioblastoma	Enrichment	MGMT, MSH2	2.21
25	Hereditary breast ovarian cancer syndrome	Enrichment	MLH1, MSH2, PTEN	2.17
26	Vacterl association with hydrocephalus	Enrichment	PTEN	2.15
27	Stomatin-deficient cryohydrocytosis with neurologic defects	Enrichment	SLC2A1	2.15
28	Immunodeficiency 38 with basal ganglia calcification	Enrichment	ISG15	2.15
29	Lynch syndrome 2	Enrichment	MLH1	2.15
30	Cardiomyopathy, familial hypertrophic, 6	Enrichment	PRKAG2	2.15
31	Plasminogen activator inhibitor-1 deficiency	Enrichment	SERPINE1	2.15
32	Mitochondrial dna depletion syndrome 8b	Enrichment	RRM2B	2.15
33	Papillary tumor of the pineal region	Enrichment	PTEN	2.15
34	Glycogen storage disease of heart, lethal congenital	Enrichment	PRKAG2	2.15
35	Systemic lupus erythematosus 10	Enrichment	IRF5	2.15
36	Glutathione peroxidase deficiency	Enrichment	GPX1	2.15
37	Epilepsy, idiopathic generalized 12	Enrichment	SLC2A1	2.15
38	Olmsted syndrome 2	Enrichment	PERP	2.15
39	Ataxia-telangiectasia-like disorder 2	Enrichment	PCNA	2.15
40	Inflammatory bowel disease 14	Enrichment	IRF5	2.15
41	Glioma susceptibility 2	Enrichment	PTEN	2.15
42	Skeletal muscle glycogen content and metabolism quantitative trait locus	Enrichment	PRKAG3	2.15
43	Mismatch repair cancer syndrome 2	Enrichment	MSH2	2.15
44	Immunodeficiency 65 viral infections	Enrichment	IRF9	2.15
45	Erythrokeratodermia variabilis et progressiva 7	Enrichment	PERP	2.15
46	Rectal benign neoplasm	Enrichment	MSH2	2.15
47	Ascending colon cancer	Enrichment	MSH2	2.15
48	Autosomal recessive axonal charcot-marie-tooth disease due to copper metabolism defect	Enrichment	SCO2	2.15
49	Ovarian cyst	Enrichment	MSH2	2.15
50	Epilepsy with myoclonic absences	Enrichment	SLC2A1	2.15
51	Congenital plasminogen activator inhibitor type 1 deficiency	Enrichment	SERPINE1	2.15
52	Intellectual developmental disorder, autosomal recessive 75, with neuropsychiatric features and variant lissencephaly	Enrichment	PIDD1	2.15
53	Segmental outgrowth-lipomatosis-arteriovenous malformation-epidermal nevus syndrome	Enrichment	PTEN	2.15
54	Rrm2b mitochondrial dna maintenance defects	Enrichment	RRM2B	2.15
55	Hereditary cryohydrocytosis with reduced stomatin	Enrichment	SLC2A1	2.15
56	Hepatoblastoma	Enrichment	ERCC5, MSH2	2.03
57	Malaria	Enrichment	ICAM1, TNF	1.95
58	Inherited cancer-predisposing syndrome	Enrichment	MLH1, MSH2, PTEN, TSC2	1.86
59	Fanconi renotubular syndrome 1	Enrichment	RRM2B	1.86
60	Hyperprolinemia, type ii	Enrichment	ALDH4A1	1.86
61	Dystonia 9	Enrichment	SLC2A1	1.86
62	Xeroderma pigmentosum, complementation group c	Enrichment	XPC	1.86
63	Rod-cone dystrophy, sensorineural deafness, and fanconi-type renal dysfunction	Enrichment	RRM2B	1.86
64	Xeroderma pigmentosum, complementation group e	Enrichment	DDB2	1.86
65	Progressive external ophthalmoplegia with mitochondrial dna deletions, autosomal dominant 5	Enrichment	RRM2B	1.86
66	Lymphangioleiomyomatosis	Enrichment	TSC2	1.86
67	Glut1 deficiency syndrome 1	Enrichment	SLC2A1	1.86
68	Mitochondrial dna depletion syndrome 8a	Enrichment	RRM2B	1.86
69	Neurodevelopmental disorder with hypotonia, speech delay, and dysmorphic facies	Enrichment	POLK	1.86
70	Adams-oliver syndrome 5	Enrichment	NOTCH1	1.86
71	Progressive external ophthalmoplegia with mitochondrial dna deletions, autosomal recessive 2	Enrichment	RRM2B	1.86
72	Xeroderma pigmentosum, complementation group a	Enrichment	XPC	1.86
73	Spastic paraplegia 73, autosomal dominant	Enrichment	CPT1C	1.86
74	Cebalid syndrome	Enrichment	MTOR	1.86
75	Myopia 6	Enrichment	SCO2	1.86
76	Immunodeficiency 127	Enrichment	TNF	1.86
77	Glucose transporter type 1 deficiency syndrome	Enrichment	SLC2A1	1.86
78	Smith-kingsmore syndrome	Enrichment	MTOR	1.86
79	Xeroderma pigmentosum group c	Enrichment	XPC	1.86
80	Vacterl with hydrocephalus	Enrichment	PTEN	1.86
81	Juvenile polyposis of infancy	Enrichment	PTEN	1.86
82	Xeroderma pigmentosum group e	Enrichment	DDB2	1.86
83	Breast cancer	Enrichment	MLH1, MSH2, PTEN	1.81
84	Bladder cancer	Enrichment	CDKN1A, PTEN	1.76
85	Prostate cancer	Enrichment	POLK, PTEN	1.76
86	Tuberous sclerosis 1	Enrichment	TSC2	1.68
87	Immunodeficiency 98 with autoinflammation, x-linked	Enrichment	FASLG	1.68
88	Granulomatous disease, chronic, autosomal recessive, 2	Enrichment	NCF2	1.68
89	Polycystic kidney disease, infantile severe, with tuberous sclerosis	Enrichment	TSC2	1.68
90	Xeroderma pigmentosum, complementation group g	Enrichment	ERCC5	1.68
91	Mitochondrial complex iv deficiency, nuclear type 2	Enrichment	SCO2	1.68
92	Glut1 deficiency syndrome 2	Enrichment	SLC2A1	1.68
93	Psoriatic arthritis	Enrichment	TNF	1.68
94	Tuberous sclerosis 2	Enrichment	TSC2	1.68
95	Cerebrooculofacioskeletal syndrome 3	Enrichment	ERCC5	1.68
96	Keratosis follicularis spinulosa decalvans	Enrichment	SAT1	1.68
97	Chromosome 17q23.1-q23.2 deletion syndrome	Enrichment	SLC2A1	1.68
98	Mutilating palmoplantar keratoderma with periorificial keratotic plaques	Enrichment	PERP	1.68
99	Hamartoma	Enrichment	TSC2	1.68
100	Xanthinuria, type ii	Enrichment	TSC2	1.68
101	Cellular ependymoma	Enrichment	MSH2	1.68
102	Tanycytic ependymoma	Enrichment	MSH2	1.68
103	Papillary ependymoma	Enrichment	MSH2	1.68
104	T-cell acute lymphoblastic leukemia	Enrichment	BAX	1.68
105	Migraine without aura	Enrichment	TNF	1.68
106	Idiopathic camptocormia	Enrichment	RRM2B	1.68
107	Xeroderma pigmentosum group g	Enrichment	ERCC5	1.68
108	Clear cell ependymoma	Enrichment	MSH2	1.68
109	Keratoacanthoma	Enrichment	NOTCH1	1.68
110	Vogt-koyanagi-harada disease	Enrichment	FAS	1.68
111	Fucosidosis	Enrichment	FUCA1	1.56
112	Lynch syndrome 4	Enrichment	MSH2	1.56
113	Tuberous sclerosis	Enrichment	TSC2	1.56
114	Pediatric systemic lupus erythematosus	Enrichment	SAT1	1.56
115	Glioma	Enrichment	PTEN	1.56
116	Benign ependymoma	Enrichment	MSH2	1.56
117	Pseudomyogenic hemangioendothelioma	Enrichment	SERPINE1	1.56
118	Systemic lupus erythematosus	Enrichment	IRF5, TNF	1.52
119	Kearns-sayre syndrome	Enrichment	RRM2B	1.46
120	Macrocephaly/autism syndrome	Enrichment	PTEN	1.46
121	Cox deficiency, infantile mitochondrial myopathy	Enrichment	SCO2	1.46
122	Glioblastoma	Enrichment	MSH2	1.46
123	Hemangioma	Enrichment	PTEN	1.46
124	Polyneuropathy	Enrichment	ERCC5	1.46
125	Vascular dementia	Enrichment	TNF	1.46
126	Acute megakaryocytic leukemia	Enrichment	PTEN	1.46
127	Rare isolated myopia	Enrichment	SCO2	1.46
128	Diffuse cutaneous systemic sclerosis	Enrichment	IRF5	1.46
129	Xeroderma pigmentosum-cockayne syndrome complex	Enrichment	ERCC5	1.46
130	West syndrome	Enrichment	SLC2A1, TSC2	1.42
131	Congenital nervous system abnormality	Enrichment	FUCA1, PTEN, TSC2	1.42
132	Nervous system disease	Enrichment	FUCA1, PTEN, TSC2	1.42
133	Cowden syndrome 1	Enrichment	PTEN	1.38
134	Cerebrooculofacioskeletal syndrome 1	Enrichment	ERCC5	1.38
135	Progressive external ophthalmoplegia with mitochondrial dna deletions, autosomal dominant 1	Enrichment	RRM2B	1.38
136	Mitochondrial dna depletion syndrome 1	Enrichment	SCO2	1.38
137	Limited scleroderma	Enrichment	IRF5	1.38
138	Polycystic kidney disease 1 with or without polycystic liver disease	Enrichment	TSC2	1.32
139	Multiple endocrine neoplasia, type i	Enrichment	CDKN1A	1.32
140	Thyroid cancer, nonmedullary, 2	Enrichment	PTEN	1.32
141	Renal cell carcinoma, papillary, 1	Enrichment	MTOR	1.32
142	Adams-oliver syndrome	Enrichment	NOTCH1	1.32
143	Polycystic kidney disease 1	Enrichment	TSC2	1.32
144	Follicular thyroid carcinoma	Enrichment	PTEN	1.32
145	Paroxysmal dystonia	Enrichment	SLC2A1	1.32
146	Overgrowth syndrome	Enrichment	MTOR	1.32
147	Mitochondrial dna depletion syndrome 4b	Enrichment	SCO2	1.26
148	Alternating hemiplegia of childhood	Enrichment	SLC2A1	1.26
149	Hypoplastic left heart syndrome	Enrichment	NOTCH1	1.26
150	Rheumatoid arthritis	Enrichment	IRF5	1.21
151	Myoclonic-atonic epilepsy	Enrichment	SLC2A1	1.21
152	Adult hepatocellular carcinoma	Enrichment	TSC2	1.21
153	Chronic granulomatous disease	Enrichment	NCF2	1.21
154	Colonic benign neoplasm	Enrichment	MLH1	1.21
155	Primary biliary cholangitis	Enrichment	IRF5	1.21
156	Cowden syndrome	Enrichment	PTEN	1.21
157	Melanoma	Enrichment	PTEN	1.17
158	Pectus excavatum	Enrichment	ERCC5	1.13
159	Asthma	Enrichment	TNF	1.13
160	Meningioma, familial	Enrichment	PTEN	1.13
161	Meningioma	Enrichment	PTEN	1.09
162	Aortic valve disease 1	Enrichment	NOTCH1	1.06
163	Breast-ovarian cancer, familial 1	Enrichment	MSH2	1.06
164	Acute promyelocytic leukemia	Enrichment	PML	1.06
165	Alzheimer's disease	Enrichment	TNF	1.06
166	Aortic aneurysm, familial thoracic 1	Enrichment	NOTCH1	1.03
167	Renal cell carcinoma, nonpapillary	Enrichment	MTOR	1.00
168	Autosomal dominant polycystic kidney disease	Enrichment	TSC2	1.00
169	Rare genetic intellectual disability	Enrichment	MTOR	1.00
170	Wolff-parkinson-white syndrome	Enrichment	PRKAG2	0.97
171	Melanoma, cutaneous malignant 1	Enrichment	MGMT	0.95
172	Human immunodeficiency virus type 1	Enrichment	CCL2	0.92
173	Behcet syndrome	Enrichment	FAS	0.90
174	Diffuse large b-cell lymphoma	Enrichment	PTEN	0.90
175	Developmental and epileptic encephalopathy 1	Enrichment	SLC2A1	0.79
176	Tetralogy of fallot	Enrichment	NOTCH1	0.78
177	Strabismus	Enrichment	SLC2A1	0.76
178	Autism spectrum disorder	Enrichment	PTEN, TSC2	0.75
179	Connective tissue disease	Enrichment	NOTCH1	0.70
180	Familial hypertrophic cardiomyopathy	Enrichment	PRKAG2	0.68
181	Epilepsy	Enrichment	SLC2A1	0.61
182	Benign epilepsy with centrotemporal spikes	Enrichment	SLC2A1	0.60
183	Centralopathic epilepsy	Enrichment	SLC2A1	0.58
184	Hypertrophic cardiomyopathy	Enrichment	PRKAG2	0.58
185	Familial thoracic aortic aneurysm and aortic dissection	Enrichment	NOTCH1	0.57
186	Sensorineural hearing loss	Enrichment	RRM2B	0.54
187	Myeloma, multiple	Enrichment	AURKA	0.49
188	Primary ovarian insufficiency	Enrichment	THBS1	0.47
189	Dilated cardiomyopathy	Enrichment	SCO2	0.37
190	Mitochondrial disease	Enrichment	RRM2B	0.34
191	Microcephaly	Enrichment	SLC2A1	0.24
192	Retinitis pigmentosa	Enrichment	RRM2B	0.11

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

p53 transcriptional gene network

Pathway Network for p53 transcriptional gene network

Member Pathways for p53 transcriptional gene network

Pathways in the p53 transcriptional gene network SuperPath

Associated Genes for p53 transcriptional gene network

Associated Disorders for p53 transcriptional gene network

Disorders associated with p53 transcriptional gene network SuperPath

STRING Interaction Network for p53 transcriptional gene network

Sources for p53 transcriptional gene network