p73 transcription factor network

No Pathway Network information available for p73 transcription factor network

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

Disorders associated with p73 transcription factor network SuperPath

according to GeneCards Suite gene sharing
#DisorderTypeGenesScore
1T-cell acute lymphoblastic leukemiaEnrichmentABL1, BAX4.03
2Small cell cancer of the lungEnrichmentRB1, TP733.73
3Primary ovarian insufficiencyEnrichmentAFP, NTRK1, TP63, WT13.48
4Bladder cancerEnrichmentBRCA2, CDKN1A, RB13.25
5Mosaic variegated aneuploidy syndromeEnrichmentBUB1, BUB33.07
6Colorectal cancerEnrichmentBAX, BRCA2, BUB1, EP3002.85
7Lip and oral cavity carcinomaEnrichmentABL1, RB12.71
8Ovarian cancerEnrichmentBRCA2, NTRK1, RB1, WT12.61
946,xy partial gonadal dysgenesisEnrichmentWT1, WWOX2.57
10Wilms tumor 1EnrichmentBRCA2, WT12.51
11Rapp-hodgkin syndromeEnrichmentTP632.25
12Ankyloblepharon-ectodermal defects-cleft lip/palateEnrichmentTP632.25
13Anemia, congenital, nonspherocytic hemolytic, 9EnrichmentGATA12.25
14Thrombocytopenia, x-linked, with or without dyserythropoietic anemiaEnrichmentGATA12.25
15Split-hand/foot malformation 4EnrichmentTP632.25
16Thrombocytopenia with beta-thalassemia, x-linkedEnrichmentGATA12.25
17Ankyloblepharon filiforme adnatum and cleft palateEnrichmentTP632.25
18Coloboma, ocular, with or without hearing impairment, cleft lip/palate, and/or impaired intellectual developmentEnrichmentYAP12.25
19Hydroxyacyl glutathione hydrolase deficiencyEnrichmentHAGH2.25
20Glioma susceptibility 3EnrichmentBRCA22.25
21Adult syndromeEnrichmentTP632.25
22Microcephaly 12, primary, autosomal recessiveEnrichmentCDK62.25
23Mirror movements 2EnrichmentRAD512.25
24Sessile serrated polyposis cancer syndromeEnrichmentRNF432.25
25Accelerated tumor formationEnrichmentMDM22.25
26Ciliary dyskinesia, primary, 47, and lissencephalyEnrichmentTP732.25
27Fanconi anemia, complementation group rEnrichmentRAD512.25
28Alpha-fetoprotein, hereditary persistence ofEnrichmentAFP2.25
29Lessel-kubisch syndromeEnrichmentMDM22.25
30Hyperemesis gravidarumEnrichmentGDF152.25
31Anemia, x-linked, with or without neutropenia and/or platelet abnormalitiesEnrichmentGATA12.25
32Cardioacrofacial dysplasia 2EnrichmentPRKACB2.25
33Plasminogen activator inhibitor-1 deficiencyEnrichmentSERPINE12.25
34Pancreatic cancer 2EnrichmentBRCA22.25
35Ectrodactyly, ectodermal dysplasia, and cleft lip/palate syndrome 3EnrichmentTP632.25
36Uveal coloboma-cleft lip and palate-intellectual disabilityEnrichmentYAP12.25
37Limb-mammary syndromeEnrichmentTP632.25
38Autoimmune disease, multisystem, with facial dysmorphismEnrichmentITCH2.25
39Meacham syndromeEnrichmentWT12.25
40Premature ovarian failure 21EnrichmentTP632.25
41Alpha-fetoprotein deficiencyEnrichmentAFP2.25
42Alpha-1-antitrypsin deficiencyEnrichmentSERPINA12.25
43Orofacial cleft 8EnrichmentTP632.25
44Muscular dystrophy, limb-girdle, autosomal recessive 27EnrichmentJAG22.25
45Mitochondrial complex i deficiency, nuclear type 6EnrichmentNDUFS22.25
46Hyperplastic polyposis syndromeEnrichmentRNF432.25
47Periventricular nodular heterotopia 7EnrichmentNEDD4L2.25
48Trilateral retinoblastomaEnrichmentRB12.25
49Acute megakaryoblastic leukemia in children with down syndromeEnrichmentGATA12.25
50Microcephaly 30, primary, autosomal recessiveEnrichmentBUB12.25
51Lissencephaly due to tuba1a mutationEnrichmentTUBA1A2.25
52Intellectual developmental disorder, autosomal recessive 80, with variant lissencephalyEnrichmentCASP22.25
53Leber-like hereditary optic neuropathy, autosomal recessive 2EnrichmentNDUFS22.25
54Syndromic multisystem autoimmune disease due to itch deficiencyEnrichmentITCH2.25
55Thrombocytopenia with congenital dyserythropoietic anemiaEnrichmentGATA12.25
56Hemorrhagic disease due to alpha-1-antitrypsin pittsburgh mutationEnrichmentSERPINA12.25
57Oocyte/zygote/embryo maturation arrest 21EnrichmentCHEK12.25
58Tp63-related disordersEnrichmentTP632.25
59Esophagus squamous cell carcinomaEnrichmentWWOX2.25
60Congenital plasminogen activator inhibitor type 1 deficiencyEnrichmentSERPINE12.25
61Mendelian susceptibility to mycobacterial diseases due to partial jak1 deficiencyEnrichmentJAK12.25
62Lung oat cell carcinomaEnrichmentRB12.25
63Precursor t-cell acute lymphoblastic leukemiaEnrichmentABL1, MYC2.14
64Myeloproliferative syndrome, transientEnrichmentGATA11.95
65Burkitt lymphomaEnrichmentMYC1.95
66Ectrodactyly, ectodermal dysplasia, and cleft lip/palate syndrome 1EnrichmentTP631.95
67Insensitivity to pain, congenital, with anhidrosisEnrichmentNTRK11.95
68Denys-drash syndromeEnrichmentWT11.95
69Porphyria, congenital erythropoieticEnrichmentGATA11.95
70Nephrotic syndrome, type 4EnrichmentWT11.95
71Frasier syndromeEnrichmentWT11.95
72Developmental and epileptic encephalopathy 28EnrichmentWWOX1.95
73Chromosome 13q14 deletion syndromeEnrichmentRB11.95
74Muscular dystrophy, limb-girdle, autosomal recessive 3EnrichmentTUBA1A1.95
75Spinocerebellar ataxia, autosomal recessive 12EnrichmentWWOX1.95
76Pain sensitivity quantitative trait locus 1EnrichmentNTRK11.95
77Neurodevelopmental disorder with dysmorphic facies, sleep disturbance, and brain abnormalitiesEnrichmentKAT51.95
78Congenital heart defects and skeletal malformations syndromeEnrichmentABL11.95
79Autoinflammatory disease, familial, behcet-like 3EnrichmentRELA1.95
80Menke-hennekam syndrome 2EnrichmentEP3001.95
81Autosomal recessive limb-girdle muscular dystrophy type 2dEnrichmentTUBA1A1.95
82Bladder exstrophyEnrichmentTP631.95
83Rela fusion-positive ependymomaEnrichmentRELA1.95
84Lissencephaly 3EnrichmentTUBA1A1.95
85Diffuse midline glioma, h3 k27m-mutantEnrichmentBRCA21.95
86Acute basophilic leukemiaEnrichmentGATA11.95
87Fanconi anemia, complementation group d1EnrichmentBRCA21.95
88Autoinflammation, immune dysregulation, and eosinophiliaEnrichmentJAK11.95
89Inflammatory breast carcinomaEnrichmentBRCA21.95
90Fissured tongueEnrichmentTP631.95
91Bilateral breast cancerEnrichmentBRCA21.95
92Familial retinoblastomaEnrichmentRB11.95
93Continuous spikes and waves during sleepEnrichmentTUBA1A1.95
94Desmoplastic small round cell tumorEnrichmentWT11.95
95Neuroendocrine tumor of pancreasEnrichmentBRCA21.95
96Fanconi anemia, complementation group aEnrichmentBRCA2, RAD511.79
97Severe combined immunodeficiency, autosomal recessive, t cell-negative, b cell-negative, nk cell-negative, due to adenosine deaminase deficiencyEnrichmentADA1.78
98RetinoblastomaEnrichmentRB11.78
99Thyroid carcinoma, familial medullaryEnrichmentNTRK11.78
100Mesothelioma, malignantEnrichmentWT11.78
101Intellectual developmental disorder, x-linked 109EnrichmentSERPINA11.78
102Osteogenic sarcomaEnrichmentRB11.78
103Chromosome 5q14.3 deletion syndrome, distalEnrichmentNEDD4L1.78
104Woolly hair, autosomal recessive 3EnrichmentRB11.78
105Tumor predisposition syndrome 1EnrichmentBRCA21.78
106Hypotrichosis 8EnrichmentRB11.78
107Breast implant-associated anaplastic large cell lymphomaEnrichmentJAK11.78
108High-grade b-cell lymphoma double-hit/triple-hitEnrichmentMYC1.78
109Dedifferentiated liposarcomaEnrichmentMDM21.78
110Squamous cell carcinomaEnrichmentRB11.78
111Bone osteosarcomaEnrichmentRB11.78
112Bap1 tumor predisposition syndromeEnrichmentBRCA21.78
113Respiratory failureEnrichmentTP731.78
114Tubulinopathy-associated dysgyriaEnrichmentTUBA1A1.78
115Well-differentiated liposarcomaEnrichmentMDM21.78
116Vogt-koyanagi-harada diseaseEnrichmentFAS1.78
117Cerebral palsyEnrichmentBRCA2, TUBA1A1.70
118Mirror movements 1EnrichmentRAD511.65
119Aniridia 1EnrichmentWT11.65
120ChordomaEnrichmentBRCA21.65
121Down syndromeEnrichmentGATA11.65
122Myopathy, centronuclear, 2EnrichmentBIN11.65
123Polyposis syndrome, hereditary mixed, 1EnrichmentBRCA21.65
124Autoimmune lymphoproliferative syndromeEnrichmentFAS1.65
125CholangiocarcinomaEnrichmentBRCA21.65
126Lynch syndrome 4EnrichmentRB11.65
127Malignant epithelioid hemangioendotheliomaEnrichmentYAP11.65
128Chronic myelogenous leukemia, bcr-abl1 positiveEnrichmentABL11.65
129TubulinopathyEnrichmentTUBA1A1.65
130Adenosine deaminase deficiencyEnrichmentADA1.65
131Cleft lip and alveolusEnrichmentTP631.65
132Male infertility due to gonadal dysgenesis or sperm disorderEnrichmentCHEK11.65
133Pseudomyogenic hemangioendotheliomaEnrichmentSERPINE11.65
134West syndromeEnrichmentTUBA1A, WWOX1.60
135Hereditary breast carcinomaEnrichmentBRCA2, RAD511.60
136Severe combined immunodeficiency, autosomal recessive, t cell-negative, b cell-positive, nk cell-negativeEnrichmentADA1.56
137Breast-ovarian cancer, familial 2EnrichmentBRCA21.56
138Leber congenital amaurosis 10EnrichmentWT11.56
139Rubinstein-taybi syndrome 2EnrichmentEP3001.56
140Acute megakaryocytic leukemiaEnrichmentGATA11.56
141Cleft upper lipEnrichmentTP631.56
142Li-fraumeni syndromeEnrichmentMDM21.48
143Myopathy, centronuclear, 1EnrichmentBIN11.48
144Kabuki syndrome 1EnrichmentBRCA21.48
145Rubinstein-taybi syndrome 1EnrichmentEP3001.48
146Wilms tumor, aniridia, genitourinary anomalies, and impaired intellectual development syndromeEnrichmentWT11.48
147Wilms tumor 5EnrichmentWT11.48
148Chromosome 16p13.3 deletion syndrome, proximalEnrichmentEP3001.48
149Congenital fibrosis of the extraocular musclesEnrichmentTUBA1A1.48
150Early myoclonic encephalopathyEnrichmentTUBA1A1.48
151Inherited cancer-predisposing syndromeEnrichmentBRCA2, RB1, WT11.42
152Hereditary breast ovarian cancer syndromeEnrichmentBRCA2, RAD511.42
153Esophageal cancerEnrichmentWWOX1.41
154Multiple endocrine neoplasia, type iEnrichmentCDKN1A1.41
155Polymicrogyria, bilateral perisylvian, x-linkedEnrichmentTUBA1A1.41
156Leukemia, chronic myeloidEnrichmentABL11.41
157Neuropathy, hereditary sensory and autonomic, type vEnrichmentNTRK11.41
158Moyamoya angiopathyEnrichmentABL11.41
159B-lymphoblastic leukemia/lymphoma with t(9;22)(q34.1;q11.2)EnrichmentABL11.41
160Myeloma, multipleEnrichmentBRCA2, YAP11.41
161Isolated growth hormone deficiency, type iaEnrichmentBRCA21.36
162CryptorchidismEnrichmentTUBA1A1.36
163Isolated split hand-split foot malformationEnrichmentTP631.36
164Difference of sex developmentEnrichmentWT11.36
165Tracheoesophageal fistula with or without esophageal atresiaEnrichmentBRCA21.31
166Charge syndromeEnrichmentEP3001.31
167Cryptorchidism, unilateral or bilateralEnrichmentTUBA1A1.31
168Ellis-van creveld syndromeEnrichmentPRKACB1.31
169PolydactylyEnrichmentBRCA21.31
170Leukemia, acute lymphoblastic 3EnrichmentWT11.31
171Bilateral perisylvian polymicrogyriaEnrichmentTUBA1A1.31
172Omenn syndromeEnrichmentADA1.26
173Isolated tracheo-esophageal fistulaEnrichmentBRCA21.26
17446,xy complete gonadal dysgenesisEnrichmentWT11.22
175Uterine corpus cancerEnrichmentBRCA21.22
176Familial colorectal cancer type xEnrichmentBRCA21.22
177Breast cancerEnrichmentBRCA2, RAD511.18
178Microphthalmia/coloboma 12EnrichmentYAP11.15
179Breast-ovarian cancer, familial 1EnrichmentBRCA21.15
180Pulmonary disease, chronic obstructiveEnrichmentSERPINA11.15
181Acute promyelocytic leukemiaEnrichmentPML1.15
182Premature menopauseEnrichmentTP631.15
183Chromosome 1p36 deletion syndromeEnrichmentUBE4B1.15
184Protein-deficiency anemiaEnrichmentGATA11.15
185MedulloblastomaEnrichmentBRCA21.12
186Lung cancer susceptibility 3EnrichmentRB11.12
187Periventricular nodular heterotopiaEnrichmentNEDD4L1.12
188Heart diseaseEnrichmentABL11.12
189Cleft lip/palateEnrichmentTP631.12
190Coloboma of maculaEnrichmentYAP11.09
191Polydactyly, postaxial, type a1EnrichmentEP3001.09
192Corpus callosum, agenesis ofEnrichmentTUBA1A1.09
193Kidney diseaseEnrichmentWT11.09
194Isolated corpus callosum agenesisEnrichmentTUBA1A1.09
195Rare genetic intellectual disabilityEnrichmentEP3001.09
196Intellectual disability-hypoplastic corpus callosum-preauricular tag syndromeEnrichmentTUBA1A1.09
197Male infertility with spermatogenesis disorderEnrichmentTP631.09
198RhabdomyosarcomaEnrichmentBRCA21.07
199Dandy-walker syndromeEnrichmentTUBA1A1.04
200Behcet syndromeEnrichmentFAS0.99
201Diffuse large b-cell lymphomaEnrichmentBRCA20.99
202Esophageal atresia/tracheoesophageal fistulaEnrichmentBRCA20.99
203Focal segmental glomerulosclerosisEnrichmentWT10.97
204Endometrial cancerEnrichmentBRCA20.95
205LissencephalyEnrichmentTUBA1A0.95
206HepatoblastomaEnrichmentBRCA20.95
207Congenital nervous system abnormalityEnrichmentTUBA1A, WWOX0.92
208Nervous system diseaseEnrichmentTUBA1A, WWOX0.92
209Diamond-blackfan anemia 1EnrichmentGATA10.92
210Pancreatic cancerEnrichmentBRCA20.88
211Developmental and epileptic encephalopathy 1EnrichmentWWOX0.88
212Tetralogy of fallotEnrichmentHEY20.87
213Prostate cancerEnrichmentBRCA20.82
214Differentiated thyroid carcinomaEnrichmentNTRK10.82
215MicrocephalyEnrichmentABL1, EP3000.82
216Lung cancerEnrichmentFAS0.78
217Cystic fibrosisEnrichmentSERPINA10.78
218Primary autosomal recessive microcephalyEnrichmentCDK60.78
219Severe combined immunodeficiencyEnrichmentADA0.77
220Genetic steroid-resistant nephrotic syndromeEnrichmentWT10.76
221Diamond-blackfan anemiaEnrichmentGATA10.74
222Fetal akinesia deformation sequence 1EnrichmentTUBA1A0.73
223Leber hereditary optic neuropathy, modifier ofEnrichmentNDUFS20.73
224Mitochondrial complex i deficiency, nuclear type 1EnrichmentNDUFS20.72
225EpilepsyEnrichmentWWOX0.70
226Benign epilepsy with centrotemporal spikesEnrichmentWWOX0.69
227Centralopathic epilepsyEnrichmentWWOX0.67
228Gastric cancerEnrichmentBRCA20.67
229Familial thoracic aortic aneurysm and aortic dissectionEnrichmentHEY20.66
230ThrombocytopeniaEnrichmentGATA10.63
231Undetermined early-onset epileptic encephalopathyEnrichmentWWOX0.57
232Leber plus diseaseEnrichmentNDUFS20.38

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