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Paradoxical activation of RAF signaling by kinase inactive BRAF
SuperPath
Pathway network
for
Paradoxical activation of RAF signaling by kinase inactive BRAF
SuperPath
5
Pathways
in the
Paradoxical activation of RAF signaling by kinase inactive BRAF
SuperPath
Signaling by moderate kinase activity BRAF mutants
Paradoxical activation of RAF signaling by kinase inactive BRAF
Signaling by high-kinase activity BRAF mutants
Signaling by RAS mutants
MAP2K and MAPK activation
54
Genes
in the
Paradoxical activation of RAF signaling by kinase inactive BRAF
SuperPath
ARAF
ARRB1
ARRB2
BRAF
CSK
FGA
FGB
FGG
FN1
HRAS
ITGA2B
ITGB3
KRAS
MARK3
NRAS
PEBP1
MAPK1
MAPK3
MAP2K1
MAP2K2
RAF1
RAP1A
RAP1B
SRC
TLN1
VCL
VWF
YWHAB
IQGAP1
KSR1
CNKSR1
CNKSR2
APBB1IP
KSR2
MIR6852
JAK2
MAP3K11
PHB
BRAP
NF1
RASA1
RASA2
RASAL1
SYNGAP1
RASAL2
RASA4
RASA3
RASAL3
DAB2IP
MIR5004
LAMTOR3
LAMTOR2
IL17RD
WDR83
*Darkness represents the genes rank within the SuperPath, via the multiplicity of each gene in the constituent pathways.
STRING interaction network
for
Paradoxical activation of RAF signaling by kinase inactive BRAF
SuperPath