Pathways affected in adenoid cystic carcinoma

No Pathway Network information available for Pathways affected in adenoid cystic carcinoma

Pathways in the Pathways affected in adenoid cystic carcinoma SuperPath

#	Name	Source	Genes
1	Pathways affected in adenoid cystic carcinoma	WikiPathways	AKT1 ARID1A ARID4B ARID5B ATM ATRX BCOR BCORL1 BRCA1 BRD1 CEBPA CMTR2 CNTN6 CREBBP CTBP1 DTX4 EP300 ERBB2 ERBIN FBXW7 FGF16 FGFR4 FOXO3 FOXP2 H1-4 H2AC16 HRAS IL17RD INSRR JMJD1C KANSL1 KAT6A KDM6A KDM6B KMT2C MAGI1 MAGI2 MAML3 MAP2K2 MAX MGA MORF4L1 MYB MYBL1 MYCBP MYCN NCOR1 NFIB NOTCH1 NSD1 PIK3CA PRKDC PTEN RAF1 SETD2 SMARCA2 SMARCE1 SMC1A SRCAP TLK1 TP53 UHRF1 (see all 62) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	TLK1	Tousled Like Kinase 1	Protein Coding	1
2	MAGI2	Membrane Associated Guanylate Kinase, WW And PDZ Domain Containing 2	Protein Coding	1
3	NCOR1	Nuclear Receptor Corepressor 1	Protein Coding	1
4	FOXP2	Forkhead Box P2	Protein Coding	1
5	MAGI1	Membrane Associated Guanylate Kinase, WW And PDZ Domain Containing 1	Protein Coding	1
6	FGF16	Fibroblast Growth Factor 16	Protein Coding	1
7	ARID5B	AT-Rich Interaction Domain 5B	Protein Coding	1
8	H2AC16	H2A Clustered Histone 16	Protein Coding	1
9	ARID1A	AT-Rich Interaction Domain 1A	Protein Coding	1
10	SMC1A	Structural Maintenance Of Chromosomes 1A	Protein Coding	1
11	KAT6A	Lysine Acetyltransferase 6A	Protein Coding	1
12	KDM6A	Lysine Demethylase 6A	Protein Coding	1
13	TP53	Tumor Protein P53	Protein Coding	1
14	BRCA1	BRCA1 DNA Repair Associated	Protein Coding	1
15	SMARCE1	SWI/SNF Related BAF Chromatin Remodeling Complex Subunit E1	Protein Coding	1
16	SMARCA2	SWI/SNF Related BAF Chromatin Remodeling Complex Subunit ATPase 2	Protein Coding	1
17	NSD1	Nuclear Receptor Binding SET Domain Protein 1	Protein Coding	1
18	BCORL1	BCL6 Corepressor Like 1	Protein Coding	1
19	RAF1	Raf-1 Proto-Oncogene, Serine/Threonine Kinase	Protein Coding	1
20	KMT2C	Lysine Methyltransferase 2C	Protein Coding	1
21	PTEN	Phosphatase And Tensin Homolog	Protein Coding	1
22	MAP2K2	Mitogen-Activated Protein Kinase Kinase 2	Protein Coding	1
23	ERBIN	Erbb2 Interacting Protein	Protein Coding	1
24	PRKDC	Protein Kinase, DNA-Activated, Catalytic Subunit	Protein Coding	1
25	CMTR2	Cap Methyltransferase 2	Protein Coding	1
26	MAML3	Mastermind Like Transcriptional Coactivator 3	Protein Coding	1
27	FBXW7	F-Box And WD Repeat Domain Containing 7	Protein Coding	1
28	BCOR	BCL6 Corepressor	Protein Coding	1
29	IL17RD	Interleukin 17 Receptor D	Protein Coding	1
30	ATRX	ATRX Chromatin Remodeler	Protein Coding	1
31	PIK3CA	Phosphatidylinositol-4,5-Bisphosphate 3-Kinase Catalytic Subunit Alpha	Protein Coding	1
32	ARID4B	AT-Rich Interaction Domain 4B	Protein Coding	1
33	NOTCH1	Notch Receptor 1	Protein Coding	1
34	NFIB	Nuclear Factor I B	Protein Coding	1
35	ATM	ATM Serine/Threonine Kinase	Protein Coding	1
36	MYCN	MYCN Proto-Oncogene, BHLH Transcription Factor	Protein Coding	1
37	MYBL1	MYB Proto-Oncogene Like 1	Protein Coding	1
38	MYB	MYB Proto-Oncogene, Transcription Factor	Protein Coding	1
39	MAX	MYC Associated Transcriptional Regulator X	Protein Coding	1
40	INSRR	Insulin Receptor Related Receptor	Protein Coding	1
41	HRAS	HRas Proto-Oncogene, GTPase	Protein Coding	1
42	H1-4	H1.4 Linker Histone, Cluster Member	Protein Coding	1
43	UHRF1	Ubiquitin Like With PHD And Ring Finger Domains 1	Protein Coding	1
44	SETD2	SET Domain Containing 2, Histone Lysine Methyltransferase	Protein Coding	1
45	KANSL1	KAT8 Regulatory NSL Complex Subunit 1	Protein Coding	1
46	CNTN6	Contactin 6	Protein Coding	1
47	MYCBP	MYC Binding Protein	Protein Coding	1
48	BRD1	Bromodomain Containing 1	Protein Coding	1
49	MGA	MAX Dimerization Protein MGA	Protein Coding	1
50	DTX4	Deltex E3 Ubiquitin Ligase 4	Protein Coding	1
51	KDM6B	Lysine Demethylase 6B	Protein Coding	1
52	FOXO3	Forkhead Box O3	Protein Coding	1
53	FGFR4	Fibroblast Growth Factor Receptor 4	Protein Coding	1
54	JMJD1C	Jumonji Domain Containing 1C	Protein Coding	1
55	AKT1	AKT Serine/Threonine Kinase 1	Protein Coding	1
56	ERBB2	Erb-B2 Receptor Tyrosine Kinase 2	Protein Coding	1
57	EP300	EP300 Lysine Acetyltransferase	Protein Coding	1
58	CTBP1	C-Terminal Binding Protein 1	Protein Coding	1
59	CREBBP	CREB Binding Lysine Acetyltransferase	Protein Coding	1
60	MORF4L1	Mortality Factor 4 Like 1	Protein Coding	1
61	SRCAP	Snf2 Related CREBBP Activator Protein	Protein Coding	1
62	CEBPA	CCAAT Enhancer Binding Protein Alpha	Protein Coding	1

Disorders associated with Pathways affected in adenoid cystic carcinoma SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Bladder cancer	Enrichment	ARID1A, ATM, BRCA1, ERBB2, HRAS, KDM6A, PIK3CA, PTEN, TP53	10.82
2	Myeloma, multiple	Enrichment	ATM, BCORL1, CREBBP, H1-4, H2AC16, KMT2C, MGA, TP53	9.76
3	Colorectal cancer	Enrichment	AKT1, ARID1A, ATM, BRCA1, EP300, ERBB2, FBXW7, PIK3CA, TP53	9.68
4	Gastric cancer	Enrichment	ATM, BRCA1, ERBB2, PIK3CA, PTEN, TP53	7.42
5	Hereditary breast carcinoma	Enrichment	AKT1, ATM, BRCA1, PIK3CA, PTEN, TP53	7.36
6	Adenoid cystic carcinoma	Enrichment	MYB, MYBL1, NFIB	7.04
7	Prostate cancer	Enrichment	ATM, BRCA1, PIK3CA, PTEN, TP53	6.73
8	Meningioma	Enrichment	AKT1, PIK3CA, PTEN, SMARCE1	6.72
9	Ovarian cancer	Enrichment	AKT1, ATM, BRCA1, ERBB2, PIK3CA, PTEN, TP53	6.44
10	Rhabdomyosarcoma	Enrichment	BRCA1, HRAS, PTEN, TP53	6.16
11	Breast cancer	Enrichment	AKT1, ATM, BRCA1, PIK3CA, PTEN, TP53	5.95
12	Breast adenocarcinoma	Enrichment	AKT1, PIK3CA, TP53	5.74
13	Inherited cancer-predisposing syndrome	Enrichment	ATM, BRCA1, CEBPA, MAX, PTEN, SMARCE1, TP53	5.65
14	Endometrial cancer	Enrichment	ATM, BRCA1, PIK3CA, PTEN	5.65
15	Cowden syndrome	Enrichment	AKT1, PIK3CA, PTEN	5.13
16	Autism spectrum disorder	Enrichment	CNTN6, KAT6A, KDM6A, KMT2C, PTEN, SETD2	5.00
17	Lung non-small cell carcinoma	Enrichment	ERBB2, HRAS, PIK3CA	4.84
18	Uterine corpus cancer	Enrichment	ATM, BRCA1, PTEN	4.84
19	Lip and oral cavity carcinoma	Enrichment	HRAS, PIK3CA, TP53	4.71
20	Acute myeloid leukemia with kat6a-crebbp fusion	Enrichment	CREBBP, KAT6A	4.69
21	Leukemia, acute myeloid	Enrichment	BCOR, CEBPA, NSD1, TP53	4.50
22	Noonan syndrome and noonan-related syndrome	Enrichment	HRAS, MAP2K2, RAF1	4.40
23	Koolen-de vries syndrome	Enrichment	ATM, KANSL1	4.21
24	Atypical teratoid rhabdoid tumor	Enrichment	ATRX, TP53	4.21
25	Anaplastic astrocytoma	Enrichment	ATRX, TP53	4.21
26	Adenocarcinoma	Enrichment	ATM, TP53	4.21
27	Keratoacanthoma	Enrichment	NOTCH1, PIK3CA	4.21
28	Diffuse large b-cell lymphoma	Enrichment	CREBBP, PTEN, TP53	4.08
29	Hereditary breast ovarian cancer syndrome	Enrichment	ATM, BRCA1, PTEN, TP53	3.95
30	Noonan syndrome 1	Enrichment	HRAS, MAP2K2, RAF1	3.82
31	Pancreatic cancer	Enrichment	ATM, BRCA1, TP53	3.71
32	Acute megakaryocytic leukemia	Enrichment	PTEN, TP53	3.69
33	Hemimegalencephaly	Enrichment	PIK3CA, PTEN	3.69
34	Hydrops fetalis, nonimmune	Enrichment	ARID1A, HRAS, NSD1	3.66
35	Rasopathy	Enrichment	HRAS, MAP2K2, RAF1	3.66
36	Cowden syndrome 1	Enrichment	PIK3CA, PTEN	3.52
37	Rubinstein-taybi syndrome 1	Enrichment	CREBBP, EP300	3.52
38	Chromosome 16p13.3 deletion syndrome, proximal	Enrichment	CREBBP, EP300	3.52
39	Non-immune hydrops fetalis	Enrichment	ARID1A, HRAS, NSD1	3.43
40	Lung cancer	Enrichment	BRCA1, ERBB2, PIK3CA	3.39
41	Nevus, epidermal	Enrichment	HRAS, PIK3CA	3.37
42	Thyroid cancer, nonmedullary, 2	Enrichment	HRAS, PTEN	3.37
43	Squamous cell carcinoma, head and neck	Enrichment	PTEN, TP53	3.37
44	Noonan syndrome 3	Enrichment	HRAS, RAF1	3.37
45	Gallbladder cancer	Enrichment	PIK3CA, TP53	3.37
46	Follicular thyroid carcinoma	Enrichment	HRAS, PTEN	3.37
47	Melanocytic nevus syndrome, congenital	Enrichment	HRAS, RAF1	3.25
48	Glioma susceptibility 1	Enrichment	ERBB2, TP53	3.25
49	Charge syndrome	Enrichment	EP300, KDM6A	3.14
50	Arteriovenous malformation	Enrichment	HRAS, PIK3CA	3.14
51	Adult hepatocellular carcinoma	Enrichment	PIK3CA, TP53	3.14
52	Primary hyperaldosteronism	Enrichment	ATRX, TP53	3.14
53	Leukemia, chronic lymphocytic	Enrichment	ATM, TP53	3.04
54	Myopathy, x-linked, with excessive autophagy	Enrichment	HRAS, PIK3CA	3.04
55	Meningioma, familial	Enrichment	PTEN, SMARCE1	2.96
56	Congenital nervous system abnormality	Enrichment	ATRX, CREBBP, PTEN, SMC1A	2.86
57	Nervous system disease	Enrichment	ATRX, CREBBP, PTEN, SMC1A	2.86
58	Breast-ovarian cancer, familial 1	Enrichment	ATM, BRCA1	2.81
59	Lung cancer susceptibility 3	Enrichment	ERBB2, TP53	2.74
60	Coffin-siris syndrome 1	Enrichment	ARID1A, SMARCE1	2.68
61	Renal cell carcinoma, nonpapillary	Enrichment	ATM, SETD2	2.68
62	Corpus callosum, agenesis of	Enrichment	CREBBP, SETD2	2.68
63	Isolated corpus callosum agenesis	Enrichment	CREBBP, SETD2	2.68
64	Rare genetic intellectual disability	Enrichment	CREBBP, EP300	2.68
65	Intellectual disability-hypoplastic corpus callosum-preauricular tag syndrome	Enrichment	CREBBP, SETD2	2.68
66	Gliosarcoma	Enrichment	ATM, TP53	2.63
67	Microcephaly	Enrichment	ARID1A, ATRX, EP300, SMC1A	2.62
68	Giant cell glioblastoma	Enrichment	ATM, TP53	2.57
69	Hepatocellular carcinoma	Enrichment	PIK3CA, TP53	2.35
70	Palmoplantar keratoderma, punctate type ii	Enrichment	BRCA1	2.34
71	Macrodactyly	Enrichment	PIK3CA	2.34
72	Proteus syndrome	Enrichment	AKT1	2.34
73	Paget disease, extramammary	Enrichment	ERBB2	2.34
74	Floating-harbor syndrome	Enrichment	SRCAP	2.34
75	Developmental and epileptic encephalopathy 85 with or without midline brain defects	Enrichment	SMC1A	2.34
76	Vacterl association with hydrocephalus	Enrichment	PTEN	2.34
77	Shukla-vernon syndrome	Enrichment	BCORL1	2.34
78	Kabuki syndrome 2	Enrichment	KDM6A	2.34
79	Noonan syndrome 5	Enrichment	RAF1	2.34
80	Megalencephaly, autosomal dominant	Enrichment	PIK3CA	2.34
81	Cardiomyopathy, dilated, 1nn	Enrichment	RAF1	2.34
82	Cowden syndrome 5	Enrichment	PIK3CA	2.34
83	Coffin-siris syndrome 5	Enrichment	SMARCE1	2.34
84	Cerebral cavernous malformations 4	Enrichment	PIK3CA	2.34
85	Visceral neuropathy, familial, 2, autosomal recessive	Enrichment	ERBB2	2.34
86	Intellectual disability-hypotonic facies syndrome, x-linked, 1	Enrichment	ATRX	2.34
87	Intellectual developmental disorder, autosomal dominant 70	Enrichment	SETD2	2.34
88	Bone marrow failure syndrome 5	Enrichment	TP53	2.34
89	Macrocephaly, acquired, with impaired intellectual development	Enrichment	NFIB	2.34
90	Papilloma of choroid plexus	Enrichment	TP53	2.34
91	Basal cell carcinoma 7	Enrichment	TP53	2.34
92	Anaplastic thyroid carcinoma	Enrichment	TP53	2.34
93	Infant-type hemispheric glioma	Enrichment	BRCA1	2.34
94	Metacarpal 4-5 fusion	Enrichment	FGF16	2.34
95	Papillary tumor of the pineal region	Enrichment	PTEN	2.34
96	Rahman syndrome	Enrichment	H1-4	2.34
97	Hemifacial myohyperplasia	Enrichment	PIK3CA	2.34
98	Capillary malformation of the lower lip, lymphatic malformation of face and neck, asymmetry of face and limbs, and partial/generalized overgrowth	Enrichment	PIK3CA	2.34
99	Leopard syndrome 2	Enrichment	RAF1	2.34
100	Immunodeficiency 26 with or without neurologic abnormalities	Enrichment	PRKDC	2.34
101	Cardiofaciocutaneous syndrome 4	Enrichment	MAP2K2	2.34
102	Polydactyly-macrocephaly syndrome	Enrichment	MAX	2.34
103	Cowden syndrome 6	Enrichment	AKT1	2.34
104	Hypogonadotropic hypogonadism 18 with or without anosmia	Enrichment	IL17RD	2.34
105	Arboleda-tham syndrome	Enrichment	KAT6A	2.34
106	Endometrial serous adenocarcinoma	Enrichment	ATM	2.34
107	Glioma susceptibility 2	Enrichment	PTEN	2.34
108	Ductal carcinoma in situ	Enrichment	TP53	2.34
109	Kleefstra syndrome 2	Enrichment	KMT2C	2.34
110	Blepharophimosis-impaired intellectual development syndrome	Enrichment	SMARCA2	2.34
111	Menke-hennekam syndrome 1	Enrichment	CREBBP	2.34
112	Trigonitis	Enrichment	RAF1	2.34
113	Developmental delay, hypotonia, musculoskeletal defects, and behavioral abnormalities	Enrichment	SRCAP	2.34
114	Segmental progressive overgrowth syndrome with fibroadipose hyperplasia	Enrichment	PIK3CA	2.34
115	Thyroid gland undifferentiated carcinoma	Enrichment	TP53	2.34
116	Luscan-lumish syndrome	Enrichment	SETD2	2.34
117	Small-cell carcinoma of the ovary of hypercalcemic type	Enrichment	TP53	2.34
118	Developmental delay, hypotonia, and impaired language	Enrichment	FBXW7	2.34
119	Rabin-pappas syndrome	Enrichment	SETD2	2.34
120	Rubinstein-taybi syndrome due to 16p13.3 microdeletion	Enrichment	CREBBP	2.34
121	Hypospadias	Enrichment	PIK3CA	2.34
122	Diffuse pediatric-type high-grade glioma, h3-wildtype and idh-wildtype	Enrichment	TP53	2.34
123	Premature ovarian failure 26	Enrichment	MGA	2.34
124	Facial cleft	Enrichment	SMARCE1	2.34
125	Gastric neuroendocrine neoplasm	Enrichment	ATRX	2.34
126	B-cell non-hodgkin lymphoma	Enrichment	ATM	2.34
127	Choroid plexus cancer	Enrichment	TP53	2.34
128	Rare venous malformation	Enrichment	PIK3CA	2.34
129	Central nervous system germinoma	Enrichment	JMJD1C	2.34
130	Diaphragmatic eventration	Enrichment	PIK3CA	2.34
131	Oligoasthenoteratozoospermia	Enrichment	BCORL1	2.34
132	Acute myeloid leukemia with mutated cebpa	Enrichment	CEBPA	2.34
133	Pik3ca-related overgrowth spectrum	Enrichment	PIK3CA	2.34
134	7q31 microdeletion syndrome	Enrichment	FOXP2	2.34
135	Menke-hennekam syndrome	Enrichment	CREBBP	2.34
136	5q35 microduplication syndrome	Enrichment	NSD1	2.34
137	Pleomorphic xanthoastrocytoma	Enrichment	TP53	2.34
138	Rare combined vascular malformation	Enrichment	PIK3CA	2.34
139	Cavernous lymphangioma	Enrichment	PIK3CA	2.34
140	Pik3ca-related overgrowth syndrome	Enrichment	PIK3CA	2.34
141	Phakomatosis pigmentokeratotica	Enrichment	HRAS	2.34
142	Segmental outgrowth-lipomatosis-arteriovenous malformation-epidermal nevus syndrome	Enrichment	PTEN	2.34
143	Hemihyperplasia-multiple lipomatosis syndrome	Enrichment	PIK3CA	2.34
144	Eccrine angiomatous hamartoma	Enrichment	PIK3CA	2.34
145	Autosomal dominant combined immunodeficiency due to erbin deficiency	Enrichment	ERBIN	2.34
146	Macrodactyly of toe	Enrichment	PIK3CA	2.34
147	Serous carcinoma of the corpus uteri	Enrichment	ERBB2	2.34
148	Primary peritoneal carcinoma	Enrichment	BRCA1	2.34
149	Scoliosis	Enrichment	CREBBP, NSD1	2.27
150	Holoprosencephaly 2	Enrichment	NSD1	2.04
151	Adrenocortical carcinoma, hereditary	Enrichment	TP53	2.04
152	Costello syndrome	Enrichment	HRAS	2.04
153	Thumb deformity	Enrichment	CREBBP	2.04
154	Microphthalmia, syndromic 1	Enrichment	BCOR	2.04
155	Microphthalmia, syndromic 2	Enrichment	BCOR	2.04
156	Cervical cancer	Enrichment	TP53	2.04
157	Cornelia de lange syndrome 2	Enrichment	SMC1A	2.04
158	Alpha-thalassemia myelodysplasia syndrome	Enrichment	ATRX	2.04
159	Keratosis, seborrheic	Enrichment	PIK3CA	2.04
160	Adams-oliver syndrome 5	Enrichment	NOTCH1	2.04
161	Noonan syndrome 8	Enrichment	PIK3CA	2.04
162	Lymphoma, hodgkin, classic	Enrichment	TP53	2.04
163	Alpha-thalassemia/impaired intellectual development syndrome, x-linked	Enrichment	ATRX	2.04
164	Fanconi anemia, complementation group s	Enrichment	BRCA1	2.04
165	Hypotonia, ataxia, developmental delay, and tooth enamel defect syndrome	Enrichment	CTBP1	2.04
166	Cardiac valvular dysplasia, x-linked	Enrichment	ATM	2.04
167	Nephrotic syndrome, type 15	Enrichment	MAGI2	2.04
168	Menke-hennekam syndrome 2	Enrichment	EP300	2.04
169	Pancreatic cancer 4	Enrichment	BRCA1	2.04
170	Acute basophilic leukemia	Enrichment	MYB	2.04
171	Kleefstra syndrome	Enrichment	KMT2C	2.04
172	Rosette-forming glioneuronal tumor	Enrichment	PIK3CA	2.04
173	Congenital fibrosarcoma	Enrichment	TP53	2.04
174	High grade glioma	Enrichment	ATM	2.04
175	Li-fraumeni syndrome 1	Enrichment	TP53	2.04
176	Sarcoma	Enrichment	TP53	2.04
177	Angiocentric glioma	Enrichment	MYB	2.04
178	Megalencephaly-polydactyly syndrome	Enrichment	MYCN	2.04
179	Cervix carcinoma	Enrichment	TP53	2.04
180	Hodgkin's lymphoma	Enrichment	TP53	2.04
181	T-cell prolymphocytic leukemia	Enrichment	ATM	2.04
182	Inflammatory breast carcinoma	Enrichment	BRCA1	2.04
183	Stolerman neurodevelopmental syndrome	Enrichment	KDM6B	2.04
184	Blepharophimosis - intellectual disability syndrome	Enrichment	SMARCA2	2.04
185	Alpha thalassemia-x-linked intellectual disability syndrome	Enrichment	ATRX	2.04
186	Peritoneum cancer	Enrichment	BRCA1	2.04
187	Bilateral breast cancer	Enrichment	BRCA1	2.04
188	Vacterl with hydrocephalus	Enrichment	PTEN	2.04
189	Deletion 5q35	Enrichment	NSD1	2.04
190	Kleefstra syndrome due to a point mutation	Enrichment	KMT2C	2.04
191	Familial retinoblastoma	Enrichment	MYCN	2.04
192	Juvenile polyposis of infancy	Enrichment	PTEN	2.04
193	Pleomorphic rhabdomyosarcoma	Enrichment	TP53	2.04
194	Tafro syndrome	Enrichment	MAP2K2	2.04
195	Wooly hair nevus	Enrichment	HRAS	2.04
196	Retinoblastoma	Enrichment	MYCN	1.86
197	Ataxia-telangiectasia	Enrichment	ATM	1.86
198	Polycythemia vera	Enrichment	ATM	1.86
199	Pompe disease, infantile-onset	Enrichment	PIK3CA	1.86
200	Weaver syndrome	Enrichment	NSD1	1.86
201	Osteogenic sarcoma	Enrichment	TP53	1.86
202	Nasopharyngeal carcinoma	Enrichment	TP53	1.86
203	Congenital lipomatous overgrowth, vascular malformations, and epidermal nevi	Enrichment	PIK3CA	1.86
204	Tethered spinal cord syndrome	Enrichment	CREBBP	1.86
205	Large congenital melanocytic nevus	Enrichment	HRAS	1.86
206	Coffin-siris syndrome 2	Enrichment	ARID1A	1.86
207	Alpha thalassemia-intellectual disability syndrome type 1	Enrichment	ATRX	1.86
208	Squamous cell carcinoma	Enrichment	TP53	1.86
209	Intraocular pressure quantitative trait locus	Enrichment	CREBBP	1.86
210	Periventricular leukomalacia	Enrichment	ARID1A	1.86
211	Laryngeal squamous cell carcinoma	Enrichment	PTEN	1.86
212	Bone osteosarcoma	Enrichment	TP53	1.86
213	Spermatocytoma	Enrichment	HRAS	1.86
214	Childhood apraxia of speech	Enrichment	FOXP2	1.86
215	Spindle cell sarcoma	Enrichment	MGA	1.86
216	Schimmelpenning-feuerstein-mims syndrome	Enrichment	HRAS	1.74
217	Cardiofaciocutaneous syndrome 1	Enrichment	MAP2K2	1.74
218	Small cell cancer of the lung	Enrichment	TP53	1.74
219	Thyroid cancer, nonmedullary, 1	Enrichment	TP53	1.74
220	Polyposis syndrome, hereditary mixed, 1	Enrichment	BRCA1	1.74
221	Nicolaides-baraitser syndrome	Enrichment	SMARCA2	1.74
222	Neurofibromatosis-noonan syndrome	Enrichment	MAP2K2	1.74
223	Megalencephaly-capillary malformation-polymicrogyria syndrome	Enrichment	PIK3CA	1.74
224	Cholangiocarcinoma	Enrichment	BRCA1	1.74
225	Barrett esophagus	Enrichment	ERBB2	1.74
226	Mantle cell lymphoma	Enrichment	ATM	1.74
227	Blepharophimosis	Enrichment	SMARCA2	1.74
228	Cardiofaciocutaneous syndrome	Enrichment	MAP2K2	1.74
229	Lung sarcomatoid carcinoma	Enrichment	TP53	1.74
230	Cerebrovascular disease	Enrichment	PIK3CA	1.74
231	Embryonal rhabdomyosarcoma	Enrichment	TP53	1.74
232	Sotos syndrome 1	Enrichment	NSD1	1.74
233	Noonan syndrome with multiple lentigines	Enrichment	RAF1	1.74
234	Epidermolytic nevus	Enrichment	HRAS	1.74
235	Familial cerebral cavernous malformations	Enrichment	PIK3CA	1.74
236	Smarca2-related nicolaides-baraitser syndrome	Enrichment	SMARCA2	1.74
237	Glioma	Enrichment	PTEN	1.74
238	Oculomotor apraxia	Enrichment	ATM	1.74
239	Capillary malformations, congenital	Enrichment	PIK3CA	1.64
240	Sotos syndrome	Enrichment	NSD1	1.64
241	Feingold syndrome 1	Enrichment	MYCN	1.64
242	Rhabdomyosarcoma 2	Enrichment	TP53	1.64
243	Macrocephaly/autism syndrome	Enrichment	PTEN	1.64
244	Breast-ovarian cancer, familial 2	Enrichment	BRCA1	1.64
245	Rubinstein-taybi syndrome 2	Enrichment	EP300	1.64
246	Pre-eclampsia	Enrichment	NSD1	1.64
247	Pervasive developmental disorder	Enrichment	FBXW7	1.64
248	Lymphoma	Enrichment	TP53	1.64
249	Glioblastoma	Enrichment	ATM	1.64
250	Hemangioma	Enrichment	PTEN	1.64
251	Inherited acute myeloid leukemia	Enrichment	CEBPA	1.64
252	Acute myeloid leukemia with t(8;21)(q22;q22) translocation	Enrichment	CEBPA	1.64
253	Rare pervasive developmental disorder	Enrichment	FBXW7	1.64
254	Hypertelorism	Enrichment	NSD1, PIK3CA	1.63
255	Klippel-trenaunay-weber syndrome	Enrichment	PIK3CA	1.57
256	Li-fraumeni syndrome	Enrichment	TP53	1.57
257	Kabuki syndrome 1	Enrichment	KDM6A	1.57
258	Wolf-hirschhorn syndrome	Enrichment	CTBP1	1.57
259	Hemihyperplasia, isolated	Enrichment	PIK3CA	1.57
260	Wiedemann-steiner syndrome	Enrichment	SMC1A	1.57
261	Kleefstra syndrome 1	Enrichment	KMT2C	1.57
262	Immunodeficiency-centromeric instability-facial anomalies syndrome	Enrichment	UHRF1	1.57
263	Adrenocortical carcinoma	Enrichment	TP53	1.57
264	Clear cell renal cell carcinoma	Enrichment	ATM	1.57
265	Lung squamous cell carcinoma	Enrichment	PIK3CA	1.57
266	Hypertrichosis	Enrichment	CREBBP	1.57
267	Kidney clear cell sarcoma	Enrichment	BCOR	1.57
268	Esophageal cancer	Enrichment	TP53	1.50
269	Capillary malformation-arteriovenous malformation 1	Enrichment	PIK3CA	1.50
270	Renal cell carcinoma, papillary, 1	Enrichment	ATM	1.50
271	Adams-oliver syndrome	Enrichment	NOTCH1	1.50
272	Essential thrombocythemia	Enrichment	TP53	1.50
273	Pilomyxoid astrocytoma	Enrichment	RAF1	1.50
274	Overgrowth syndrome	Enrichment	NSD1	1.50
275	B-lymphoblastic leukemia/lymphoma with t(9;22)(q34.1;q11.2)	Enrichment	TP53	1.50
276	Lymphoma, non-hodgkin, familial	Enrichment	TP53	1.44
277	Rett syndrome, congenital variant	Enrichment	SMC1A	1.44
278	Neuroblastoma	Enrichment	MYCN	1.44
279	Hypoplastic left heart syndrome	Enrichment	NOTCH1	1.44
280	Cornelia de lange syndrome 1	Enrichment	SMC1A	1.39
281	Colonic benign neoplasm	Enrichment	ATM	1.39
282	Cornelia de lange syndrome	Enrichment	SMC1A	1.39
283	Autism	Enrichment	CNTN6, CREBBP	1.37
284	Lynch syndrome 1	Enrichment	ATM	1.35
285	Melanoma	Enrichment	PTEN	1.35
286	Familial colorectal cancer	Enrichment	TP53	1.35
287	Immune deficiency disease	Enrichment	ATM	1.31
288	Myelodysplastic syndrome	Enrichment	TP53	1.31
289	Familial colorectal cancer type x	Enrichment	ATM	1.31
290	Septooptic dysplasia	Enrichment	ARID1A	1.27
291	Digeorge syndrome	Enrichment	JMJD1C	1.27
292	Aortic valve disease 1	Enrichment	NOTCH1	1.24
293	Acute promyelocytic leukemia	Enrichment	BCOR	1.24
294	Pheochromocytoma	Enrichment	MAX	1.21
295	Aortic aneurysm, familial thoracic 1	Enrichment	NOTCH1	1.21
296	Periventricular nodular heterotopia	Enrichment	BRCA1	1.21
297	Heart disease	Enrichment	CREBBP	1.21
298	Pituitary stalk interruption syndrome	Enrichment	SMARCA2	1.21
299	Polydactyly, postaxial, type a1	Enrichment	EP300	1.18
300	Lynch syndrome	Enrichment	PIK3CA	1.18
301	Cerebellar hypoplasia/atrophy, epilepsy, and global developmental delay	Enrichment	ARID1A	1.15
302	Hydrocephalus, congenital, 1	Enrichment	SETD2	1.15
303	Dandy-walker syndrome	Enrichment	SETD2	1.13
304	Syndromic intellectual disability	Enrichment	KAT6A	1.13
305	Beckwith-wiedemann syndrome	Enrichment	NSD1	1.10
306	Semilobar holoprosencephaly	Enrichment	SMC1A	1.10
307	Arteriovenous malformations of the brain	Enrichment	IL17RD	1.08
308	Craniosynostosis	Enrichment	KAT6A	1.06
309	Hepatoblastoma	Enrichment	TP53	1.04
310	Hereditary paraganglioma-pheochromocytoma syndromes	Enrichment	MAX	1.04
311	Diamond-blackfan anemia 1	Enrichment	TP53	1.00
312	Kallmann syndrome	Enrichment	IL17RD	1.00
313	Precursor t-cell acute lymphoblastic leukemia	Enrichment	MYB	1.00
314	Cardiomyopathy, familial hypertrophic, 1	Enrichment	RAF1	0.98
315	Complex neurodevelopmental disorder	Enrichment	BCORL1, SRCAP	0.96
316	Tetralogy of fallot	Enrichment	NOTCH1	0.95
317	Auditory neuropathy	Enrichment	H1-4	0.95
318	Hirschsprung disease 1	Enrichment	ERBB2	0.90
319	Differentiated thyroid carcinoma	Enrichment	HRAS	0.90
320	Connective tissue disease	Enrichment	NOTCH1	0.86
321	Familial hypertrophic cardiomyopathy	Enrichment	RAF1	0.85
322	Genetic steroid-resistant nephrotic syndrome	Enrichment	MAGI2	0.84
323	Fanconi anemia, complementation group a	Enrichment	BRCA1	0.83
324	Left ventricular noncompaction	Enrichment	RAF1	0.83
325	Diamond-blackfan anemia	Enrichment	TP53	0.82
326	Familial thoracic aortic aneurysm and aortic dissection	Enrichment	NOTCH1	0.74
327	Familial isolated dilated cardiomyopathy	Enrichment	RAF1	0.67
328	Male infertility with azoospermia or oligozoospermia due to single gene mutation	Enrichment	ATRX	0.64
329	Schizophrenia	Enrichment	CNTN6	0.62
330	Dilated cardiomyopathy	Enrichment	RAF1	0.51

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Pathways affected in adenoid cystic carcinoma

Pathway Network for Pathways affected in adenoid cystic carcinoma

Member Pathways for Pathways affected in adenoid cystic carcinoma

Pathways in the Pathways affected in adenoid cystic carcinoma SuperPath

Associated Genes for Pathways affected in adenoid cystic carcinoma

Associated Disorders for Pathways affected in adenoid cystic carcinoma

Disorders associated with Pathways affected in adenoid cystic carcinoma SuperPath

STRING Interaction Network for Pathways affected in adenoid cystic carcinoma

Sources for Pathways affected in adenoid cystic carcinoma