Pentose phosphate pathway

Sources:

#	Name	Source	Genes
1	Pentose phosphate pathway	Reactome	DERA G6PD PGD PGLS PGM2 PRPS1 PRPS1L1 PRPS2 RBKS RPE RPEL1 RPIA SHPK TALDO1 TKT (see all 15) (see less)
2	Pentose phosphate metabolism	WikiPathways	G6PD PGD PGLS RPE RPIA TALDO1 TKT (see all 7) (see less)
3	Pentose phosphate pathway disease	Reactome	RPIA TALDO1
4	Insulin effects increased synthesis of Xylulose-5-Phosphate	Reactome	TALDO1 TKT

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	TALDO1	Transaldolase 1	Protein Coding	4
2	RPIA	Ribose 5-Phosphate Isomerase A	Protein Coding	3
3	TKT	Transketolase	Protein Coding	3
4	G6PD	Glucose-6-Phosphate Dehydrogenase	Protein Coding	2
5	PGLS	6-Phosphogluconolactonase	Protein Coding	2
6	PGD	Phosphogluconate Dehydrogenase	Protein Coding	2
7	RPE	Ribulose-5-Phosphate-3-Epimerase	Protein Coding	2
8	PRPS1L1	Phosphoribosyl Pyrophosphate Synthetase 1 Like 1	Protein Coding	1
9	SHPK	Sedoheptulokinase	Protein Coding	1
10	DERA	Deoxyribose-Phosphate Aldolase	Protein Coding	1
11	PGM2	Phosphoglucomutase 2	Protein Coding	1
12	PRPS1	Phosphoribosyl Pyrophosphate Synthetase 1	Protein Coding	1
13	PRPS2	Phosphoribosyl Pyrophosphate Synthetase 2	Protein Coding	1
14	RBKS	Ribokinase	Protein Coding	1
15	RPEL1	Ribulose-5-Phosphate-3-Epimerase Like 1	Protein Coding	1

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Carbohydrate metabolic disorder	Direct
2	Short stature, developmental delay, and congenital heart defects	Enrichment	TKT	3.83
3	Transaldolase deficiency	Enrichment	TALDO1	3.53
4	Ribose 5-phosphate isomerase deficiency	Enrichment	RPIA	3.29
5	Congenital nonspherocytic hemolytic anemia	Enrichment	G6PD	3.29
6	Congenital hemolytic anemia	Enrichment	G6PD	2.99
7	Glucosephosphate dehydrogenase deficiency	Enrichment	G6PD	2.99
8	Charcot-marie-tooth disease, x-linked recessive, 5	Enrichment	PRPS1	2.96
9	Arts syndrome	Enrichment	PRPS1	2.96
10	Sedoheptulokinase deficiency	Enrichment	SHPK	2.96
11	Phosphoribosylpyrophosphate synthetase superactivity	Enrichment	PRPS1	2.96
12	Deafness, x-linked 1	Enrichment	PRPS1	2.96
13	X-linked intellectual disability-limb spasticity-retinal dystrophy-diabetes insipidus syndrome	Enrichment	PRPS1	2.96
14	Anemia, congenital, nonspherocytic hemolytic, 1	Enrichment	G6PD	2.59
15	Rare x-linked non-syndromic sensorineural deafness type dfn	Enrichment	PRPS1	2.35
16	Coronary heart disease 5	Enrichment	G6PD	2.33
17	Malaria	Enrichment	G6PD	1.93
18	Hereditary retinal dystrophy	Enrichment	PRPS1	0.56
19	Fundus dystrophy	Enrichment	PRPS1	0.56

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Pathway Network for Pentose phosphate pathway