Peptide hormone metabolism

Pathway network for the Peptide hormone metabolism SuperPath

Sources:
  • Reactome
  • WikiPathways
  • PubChem

Gene overlap in member pathways for Peptide hormone metabolism SuperPath

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

Disorders associated with Peptide hormone metabolism SuperPath

according to GeneCards Suite gene sharing
#DisorderTypeGenesScore
1Renal tubular dysgenesisEnrichmentACE, AGT, REN7.49
2Ceroid lipofuscinosis, neuronal, 10EnrichmentCTSD4.13
3Hypogonadotropic hypogonadism 23 with or without anosmiaEnrichmentLHB3.05
4Hypothyroidism, congenital, nongoitrous, 4EnrichmentTSHB3.05
5Ovary adenocarcinomaEnrichmentINHBA3.05
6Neuronal ceroid lipofuscinosisEnrichmentCTSD2.96
7Body mass index quantitative trait locus 11EnrichmentPCSK1, POMC2.93
8Congenital disorder of glycosylation, type iirEnrichmentATP6AP22.90
9Spinocerebellar ataxia 43EnrichmentMME2.90
10Microvascular complications of diabetes 3EnrichmentACE2.90
11Dystonia 31EnrichmentAOPEP2.90
12Parkinsonism with spasticity, x-linkedEnrichmentATP6AP22.90
13Intellectual developmental disorder, x-linked, syndromic, hedera typeEnrichmentATP6AP22.90
14Congenital membranous nephropathy due to maternal anti-neutral endopeptidase alloimmunizationEnrichmentMME2.90
15Charcot-marie-tooth disease type 2tEnrichmentMME2.90
16Mme-related autosomal dominant charcot marie tooth disease type 2EnrichmentMME2.90
17Syndromic x-linked intellectual disability hedera typeEnrichmentATP6AP22.90
18Drug metabolism, altered, ces1-relatedEnrichmentCES12.90
19Yt blood group antigenEnrichmentACHE2.85
20Platelet-activating factor acetylhydrolase deficiencyEnrichmentPLA2G72.85
21Butyrylcholinesterase deficiencyEnrichmentBCHE2.85
22Hypogonadotropic hypogonadism 24 with or without anosmiaEnrichmentFSHB2.75
23Tubulointerstitial kidney disease, autosomal dominant 4EnrichmentREN2.60
24Charcot-marie-tooth disease, axonal, type 2tEnrichmentMME2.60
25Maturity-onset diabetes of the young, type 10EnrichmentINS2.55
26HyperproinsulinemiaEnrichmentINS2.55
27Kowarski syndromeEnrichmentGH12.55
28Diabetes mellitus, permanent neonatal, 4EnrichmentINS2.55
29Short stature due to growth hormone qualitative anomalyEnrichmentGH12.55
30Growth delay due to insulin-like growth factor type 1 deficiencyEnrichmentIGF12.55
31Obesity, early-onset, with adrenal insufficiency and red hairEnrichmentPOMC2.51
32Body mass index quantitative trait locus 12EnrichmentPCSK12.51
33Proprotein convertase 1/3 deficiencyEnrichmentPCSK12.51
34Obesity due to pro-opiomelanocortin deficiencyEnrichmentPOMC2.51
35Type 1 diabetes mellitus 2EnrichmentINS2.38
36Isolated growth hormone deficiency, type ibEnrichmentGH12.38
37Mpv17-related mitochondrial dna maintenance defectEnrichmentUCN2.38
38Hypertension, essentialEnrichmentAGT, GNB32.27
39Isolated growth hormone deficiency, type iiEnrichmentGH12.25
40Mitochondrial dna depletion syndrome 6EnrichmentUCN2.25
41Leptin deficiency or dysfunctionEnrichmentLEP2.25
42Neonatal diabetes mellitusEnrichmentINS2.25
43Charcot-marie-tooth disease, axonal, type 2eeEnrichmentUCN2.25
44Cole-carpenter syndrome 1EnrichmentP4HB2.19
45Griscelli syndrome, type 2EnrichmentRAB27A2.19
46Spastic paraplegia 10, autosomal dominantEnrichmentKIF5A2.19
47Griscelli syndrome, type 1EnrichmentMYO5A2.19
48Elejalde neuroectodermal melanolysosomal syndromeEnrichmentMYO5A2.19
49Atrioventricular septal defect 4EnrichmentGATA42.19
50Bdv syndromeEnrichmentCPE2.19
51Myoclonus, intractable, neonatalEnrichmentKIF5A2.19
52Amyotrophic lateral sclerosis 25EnrichmentKIF5A2.19
53Body mass index quantitative trait locus 10EnrichmentFFAR42.19
54Atrial septal defect 2EnrichmentGATA42.19
55Neurodevelopmental disorder with hypotonia and autistic features with or without hyperkinetic movementsEnrichmentVAMP22.19
56Cortical dysplasia, complex, with other brain malformations 2EnrichmentKIF5C2.19
57Testicular anomalies with or without congenital heart diseaseEnrichmentGATA42.19
588p23.1 microdeletion syndromeEnrichmentGATA42.19
59Intellectual developmental disorder, autosomal dominant 42EnrichmentGNB12.19
60Neurodevelopmental disorder with seizures and brain atrophyEnrichmentEXOC72.19
61Neurodevelopmental disorder with microcephaly, seizures, and brain atrophyEnrichmentEXOC82.19
62Griscelli syndromeEnrichmentRAB27A2.19
63Adenoid ameloblastomaEnrichmentCTNNB12.19
64SirenomeliaEnrichmentCDX22.19
65Cpe-related prader-willi-like syndromeEnrichmentCPE2.19
66Partial atrioventricular septal defect with ventricular hypoplasiaEnrichmentGATA42.19
67Anorectal malformationEnrichmentCDX22.19
68Autosomal dominant charcot-marie-tooth disease type 2 due to kif5a mutationEnrichmentKIF5A2.19
69Microcystic stromal tumorEnrichmentCTNNB12.19
70Neuropathy, hereditary motor and sensory, okinawa typeEnrichmentKIF5A, MME2.18
71Insulin-like growth factor iEnrichmentIGF12.16
72Hemorrhage, intracerebralEnrichmentACE2.13
73HepatoblastomaEnrichmentCTNNB1, REN2.09
74Type 1 diabetes mellitusEnrichmentINS2.08
75Fanconi anemia, complementation group cEnrichmentAOPEP2.00
76Isolated growth hormone deficiency, type iaEnrichmentGH11.95
77Permanent neonatal diabetes mellitusEnrichmentINS1.95
78Stroke, ischemicEnrichmentACE1.90
79Keratitis, hereditaryEnrichmentPAX61.89
80Foveal hypoplasia 1EnrichmentPAX61.89
81Osteopathia striata with cranial sclerosisEnrichmentCTNNB11.89
82Griscelli syndrome, type 3EnrichmentMYO5A1.89
83Optic nerve hypoplasia, bilateralEnrichmentPAX61.89
84Hartnup disorderEnrichmentCLTRN1.89
85Night blindness, congenital stationary, type 1hEnrichmentGNB31.89
86Retinal dystrophy, iris coloboma, and comedogenic acne syndromeEnrichmentFFAR41.89
87Childhood hepatocellular carcinomaEnrichmentCTNNB11.89
88Bladder exstrophyEnrichmentISL11.89
89Frontotemporal dementia and/or amyotrophic lateral sclerosis 4EnrichmentKIF5A1.89
9046,xy sex reversal 3EnrichmentGATA41.89
91Juvenile nasopharyngeal angiofibromaEnrichmentCTNNB11.89
92Neurodevelopmental disorder with dysmorphic facies and cerebellar hypoplasiaEnrichmentEXOC21.89
93Demyelinating polyneuropathyEnrichmentKIF5A1.89
94Progressive retinal dystrophy due to retinol transport defectEnrichmentFFAR41.89
95TeratomaEnrichmentCTNNB11.89
96Skeletal muscle diseaseEnrichmentKIF5B1.89
97Cerebral visual impairmentEnrichmentGNB11.89
98Diabetes mellitusEnrichmentINS1.82
99Peripheral nervous system diseaseEnrichmentKIF5A, MME1.74
100NeuropathyEnrichmentKIF5A, MME1.74
101Desmoid disease, hereditaryEnrichmentCTNNB11.71
102Gillespie syndromeEnrichmentPAX61.71
103Neurodevelopmental disorder with spastic diplegia and visual defectsEnrichmentCTNNB11.71
104Anus, imperforateEnrichmentCTNNB11.71
105Exudative vitreoretinopathy 7EnrichmentCTNNB11.71
106Desmoid tumorEnrichmentCTNNB11.71
107Cole-carpenter syndromeEnrichmentP4HB1.71
108DystoniaEnrichmentGNB1, MYO5A1.67
109Aniridia 1EnrichmentPAX61.59
110PilomatrixomaEnrichmentCTNNB11.59
111Alazami syndromeEnrichmentCTNNB11.59
112CraniopharyngiomaEnrichmentCTNNB11.59
113Eyelid colobomaEnrichmentPAX61.59
114Transposition of the great arteriesEnrichmentGATA41.59
115Lens colobomaEnrichmentPAX61.59
116Myocardial infarctionEnrichmentACE1.56
117Maturity-onset diabetes of the youngEnrichmentINS1.56
118Type 2 diabetes mellitusEnrichmentSLC30A8, TCF7L21.52
119Hypertrophic cardiomyopathyEnrichmentKIF5B, SLC30A51.50
120Exudative vitreoretinopathy 1EnrichmentCTNNB11.49
121Kearns-sayre syndromeEnrichmentKIF5B1.49
122Ventricular septal defect 1EnrichmentGATA41.49
123Congenital heart defects, multiple types, 4EnrichmentGATA41.49
1242q23.1 microduplication syndromeEnrichmentKIF5C1.49
125AniridiaEnrichmentPAX61.49
126Coloboma of choroid and retinaEnrichmentPAX61.49
127Coloboma of optic nerveEnrichmentPAX61.42
128Osteogenesis imperfecta, type iEnrichmentP4HB1.42
129Weyers acrofacial dysostosisEnrichmentCTNNB11.42
130Wilms tumor, aniridia, genitourinary anomalies, and impaired intellectual development syndromeEnrichmentPAX61.42
131Anterior segment dysgenesis 5EnrichmentPAX61.42
132Adrenocortical carcinomaEnrichmentCTNNB11.42
133CakutEnrichmentACE1.38
134Fanconi anemia, complementation group aEnrichmentAOPEP1.37
135Gallbladder cancerEnrichmentCTNNB11.35
136Exudative vitreoretinopathyEnrichmentCTNNB11.29
137HypothyroidismEnrichmentGNB11.29
138Adult hepatocellular carcinomaEnrichmentCTNNB11.24
139Hydrops fetalisEnrichmentSLC30A51.24
140Cat eye syndromeEnrichmentPAX61.20
141Peters-plus syndromeEnrichmentPAX61.20
142Leukemia, acute lymphoblasticEnrichmentGNB11.16
143Myelodysplastic syndromeEnrichmentGNB11.16
144AutismEnrichmentSTX1A, TCF7L21.10
145Microphthalmia/coloboma 12EnrichmentPAX61.09
146MedulloblastomaEnrichmentCTNNB11.06
147Aortic aneurysm, familial thoracic 1EnrichmentGATA41.06
148Heart diseaseEnrichmentGATA41.06
14946,xy partial gonadal dysgenesisEnrichmentGATA41.06
150Breast cancerEnrichmentAOPEP1.05
151Coloboma of maculaEnrichmentPAX61.03
152Anterior segment dysgenesisEnrichmentPAX61.03
153Colorectal cancerEnrichmentAOPEP0.98
154Cleft palate, isolatedEnrichmentGNB10.98
155Polycystic liver diseaseEnrichmentCTNNB10.98
156Autosomal dominant polycystic liver diseaseEnrichmentCTNNB10.98
157Heart, malformation ofEnrichmentGATA40.96
158Patent foramen ovaleEnrichmentGATA40.96
159Ovarian cancerEnrichmentAOPEP0.92
160Williams-beuren syndromeEnrichmentSTX1A0.91
161Macs syndromeEnrichmentPAX60.91
162Hepatocellular carcinomaEnrichmentCTNNB10.87
163Attention deficit-hyperactivity disorderEnrichmentKIF5B0.87
164MicrophthalmiaEnrichmentPAX60.87
165Multisystem inflammatory syndrome in childrenEnrichmentRAB27A0.87
166Congenital stationary night blindnessEnrichmentGNB30.86
167Familial atrial fibrillationEnrichmentGATA40.84
168Autoinflammatory diseaseEnrichmentRAB27A0.84
169Inherited cancer-predisposing syndromeEnrichmentAOPEP0.81
170Tetralogy of fallotEnrichmentGATA40.81
171Auditory neuropathyEnrichmentKIF5A0.81
172StrabismusEnrichmentGNB10.79
173Bladder cancerEnrichmentCTNNB10.76
174Meckel syndrome, type 1EnrichmentEXOC40.76
175Cystic fibrosisEnrichmentSTX1A0.73
176MicrocephalyEnrichmentCTNNB1, GNB10.72
177Left ventricular noncompactionEnrichmentSLC30A50.69
178Cerebral palsyEnrichmentGNB10.65
179Hereditary spastic paraplegiaEnrichmentKIF5A0.62
180Autosomal dominant non-syndromic intellectual disabilityEnrichmentGNB10.56
181HypertelorismEnrichmentPAX60.54
182Male infertility with azoospermia or oligozoospermia due to single gene mutationEnrichmentGATA40.51
183Dilated cardiomyopathyEnrichmentKIF5B0.39
184Congenital nervous system abnormalityEnrichmentCTNNB10.30
185Nervous system diseaseEnrichmentCTNNB10.30
186Autism spectrum disorderEnrichmentGNB10.29
187Complex neurodevelopmental disorderEnrichmentTCF7L20.26

Loading...
Loading...
Loading...