Photodynamic therapy-induced HIF-1 survival signaling

No Pathway Network information available for Photodynamic therapy-induced HIF-1 survival signaling

Pathways in the Photodynamic therapy-induced HIF-1 survival signaling SuperPath

#	Name	Source	Genes
1	Photodynamic therapy-induced HIF-1 survival signaling	WikiPathways	ANGPT1 ANGPT2 ARNT BAK1 BAX BCL2A1 BCL2L1 BID BIRC5 BNIP3 BNIP3L EDN1 EGLN1 EPO HIF1A HIF1AN HK1 IGFBP1 IGFBP2 IGFBP3 LDHA MCL1 NOS2 PDHA1 PFKL PGK1 PKM PMAIP1 PTGS2 SERPINE1 SLC16A1 SLC2A1 SLC2A3 TGFA TGFB3 TP53 VEGFA (see all 37) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	PDHA1	Pyruvate Dehydrogenase E1 Subunit Alpha 1	Protein Coding	1
2	PFKL	Phosphofructokinase, Liver Type	Protein Coding	1
3	VEGFA	Vascular Endothelial Growth Factor A	Protein Coding	1
4	TP53	Tumor Protein P53	Protein Coding	1
5	TGFB3	Transforming Growth Factor Beta 3	Protein Coding	1
6	TGFA	Transforming Growth Factor Alpha	Protein Coding	1
7	BNIP3	BCL2 Interacting Protein 3	Protein Coding	1
8	SLC16A1	Solute Carrier Family 16 Member 1	Protein Coding	1
9	SLC2A3	Solute Carrier Family 2 Member 3	Protein Coding	1
10	SLC2A1	Solute Carrier Family 2 Member 1	Protein Coding	1
11	BID	BH3 Interacting Domain Death Agonist	Protein Coding	1
12	BCL2L1	BCL2 Like 1	Protein Coding	1
13	BCL2A1	BCL2 Related Protein A1	Protein Coding	1
14	BAX	BCL2 Associated X, Apoptosis Regulator	Protein Coding	1
15	BAK1	BCL2 Antagonist/Killer 1	Protein Coding	1
16	PTGS2	Prostaglandin-Endoperoxide Synthase 2	Protein Coding	1
17	EGLN1	Egl-9 Family Hypoxia Inducible Factor 1	Protein Coding	1
18	PMAIP1	Phorbol-12-Myristate-13-Acetate-Induced Protein 1	Protein Coding	1
19	PKM	Pyruvate Kinase M1/2	Protein Coding	1
20	PGK1	Phosphoglycerate Kinase 1	Protein Coding	1
21	SERPINE1	Serpin Family E Member 1	Protein Coding	1
22	NOS2	Nitric Oxide Synthase 2	Protein Coding	1
23	MCL1	MCL1 Apoptosis Regulator, BCL2 Family Member	Protein Coding	1
24	ARNT	Aryl Hydrocarbon Receptor Nuclear Translocator	Protein Coding	1
25	LDHA	Lactate Dehydrogenase A	Protein Coding	1
26	IGFBP3	Insulin Like Growth Factor Binding Protein 3	Protein Coding	1
27	IGFBP2	Insulin Like Growth Factor Binding Protein 2	Protein Coding	1
28	IGFBP1	Insulin Like Growth Factor Binding Protein 1	Protein Coding	1
29	BIRC5	Baculoviral IAP Repeat Containing 5	Protein Coding	1
30	HK1	Hexokinase 1	Protein Coding	1
31	HIF1A	Hypoxia Inducible Factor 1 Subunit Alpha	Protein Coding	1
32	ANGPT2	Angiopoietin 2	Protein Coding	1
33	ANGPT1	Angiopoietin 1	Protein Coding	1
34	EPO	Erythropoietin	Protein Coding	1
35	EDN1	Endothelin 1	Protein Coding	1
36	BNIP3L	BCL2 Interacting Protein 3 Like	Protein Coding	1
37	HIF1AN	Hypoxia Inducible Factor 1 Subunit Alpha Inhibitor	Protein Coding	1

Disorders associated with Photodynamic therapy-induced HIF-1 survival signaling SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Autosomal dominant secondary polycythemia	Enrichment	EGLN1, EPO	3.97
2	Anemia, congenital, nonspherocytic hemolytic, 5	Enrichment	HK1	2.56
3	Phosphoglycerate kinase 1 deficiency	Enrichment	PGK1	2.56
4	Stomatin-deficient cryohydrocytosis with neurologic defects	Enrichment	SLC2A1	2.56
5	Erythrocyte lactate transporter defect	Enrichment	SLC16A1	2.56
6	Microvascular complications of diabetes 2	Enrichment	EPO	2.56
7	Retinitis pigmentosa 79	Enrichment	HK1	2.56
8	Angioedema, hereditary, 5	Enrichment	ANGPT1	2.56
9	Auriculocondylar syndrome 3	Enrichment	EDN1	2.56
10	Bone marrow failure syndrome 5	Enrichment	TP53	2.56
11	Papilloma of choroid plexus	Enrichment	TP53	2.56
12	Basal cell carcinoma 7	Enrichment	TP53	2.56
13	Hemoglobin, high altitude adaptation	Enrichment	EGLN1	2.56
14	Anaplastic thyroid carcinoma	Enrichment	TP53	2.56
15	Plasminogen activator inhibitor-1 deficiency	Enrichment	SERPINE1	2.56
16	Microvascular complications of diabetes 1	Enrichment	VEGFA	2.56
17	Question mark ears, isolated	Enrichment	EDN1	2.56
18	Neuropathy, hereditary motor and sensory, russe type	Enrichment	HK1	2.56
19	Neurodevelopmental disorder with visual defects and brain anomalies	Enrichment	HK1	2.56
20	Epilepsy, idiopathic generalized 12	Enrichment	SLC2A1	2.56
21	Ductal carcinoma in situ	Enrichment	TP53	2.56
22	Erythrocytosis, familial, 5	Enrichment	EPO	2.56
23	Loeys-dietz syndrome 5	Enrichment	TGFB3	2.56
24	Thyroid gland undifferentiated carcinoma	Enrichment	TP53	2.56
25	Small-cell carcinoma of the ovary of hypercalcemic type	Enrichment	TP53	2.56
26	Diffuse pediatric-type high-grade glioma, h3-wildtype and idh-wildtype	Enrichment	TP53	2.56
27	Choroid plexus cancer	Enrichment	TP53	2.56
28	Epilepsy with myoclonic absences	Enrichment	SLC2A1	2.56
29	Pleomorphic xanthoastrocytoma	Enrichment	TP53	2.56
30	Congenital plasminogen activator inhibitor type 1 deficiency	Enrichment	SERPINE1	2.56
31	Male infertility due to obstructive azoospermia	Enrichment	PGK1	2.56
32	Hereditary cryohydrocytosis with reduced stomatin	Enrichment	SLC2A1	2.56
33	Adrenocortical carcinoma, hereditary	Enrichment	TP53	2.26
34	Fanconi-bickel syndrome	Enrichment	LDHA	2.26
35	Dystonia 9	Enrichment	SLC2A1	2.26
36	Cervical cancer	Enrichment	TP53	2.26
37	Glut1 deficiency syndrome 1	Enrichment	SLC2A1	2.26
38	Monocarboxylate transporter 1 deficiency	Enrichment	SLC16A1	2.26
39	Lymphoma, hodgkin, classic	Enrichment	TP53	2.26
40	Diamond-blackfan anemia-like	Enrichment	EPO	2.26
41	Glucose transporter type 1 deficiency syndrome	Enrichment	SLC2A1	2.26
42	Erythrocytosis, familial, 3	Enrichment	EGLN1	2.26
43	Congenital fibrosarcoma	Enrichment	TP53	2.26
44	Li-fraumeni syndrome 1	Enrichment	TP53	2.26
45	Sarcoma	Enrichment	TP53	2.26
46	Hyperinsulinemic hypoglycemia, familial, 7	Enrichment	SLC16A1	2.26
47	Loeys-dietz syndrome 4	Enrichment	TGFB3	2.26
48	Cervix carcinoma	Enrichment	TP53	2.26
49	Hodgkin's lymphoma	Enrichment	TP53	2.26
50	Lymphatic malformation 10	Enrichment	ANGPT2	2.26
51	Ketoacidosis due to monocarboxylate transporter-1 deficiency	Enrichment	SLC16A1	2.26
52	Pleomorphic rhabdomyosarcoma	Enrichment	TP53	2.26
53	Osteogenic sarcoma	Enrichment	TP53	2.09
54	Glut1 deficiency syndrome 2	Enrichment	SLC2A1	2.09
55	Nasopharyngeal carcinoma	Enrichment	TP53	2.09
56	Chromosome 17q23.1-q23.2 deletion syndrome	Enrichment	SLC2A1	2.09
57	Atypical teratoid rhabdoid tumor	Enrichment	TP53	2.09
58	Anaplastic astrocytoma	Enrichment	TP53	2.09
59	Squamous cell carcinoma	Enrichment	TP53	2.09
60	T-cell acute lymphoblastic leukemia	Enrichment	BAX	2.09
61	Adenocarcinoma	Enrichment	TP53	2.09
62	Bone osteosarcoma	Enrichment	TP53	2.09
63	Enchondromatosis	Enrichment	HIF1A	2.09
64	Huntington disease	Enrichment	SLC2A3	1.96
65	Small cell cancer of the lung	Enrichment	TP53	1.96
66	Pyruvate dehydrogenase e1-alpha deficiency	Enrichment	PDHA1	1.96
67	Thyroid cancer, nonmedullary, 1	Enrichment	TP53	1.96
68	Auriculocondylar syndrome 1	Enrichment	EDN1	1.96
69	Lung sarcomatoid carcinoma	Enrichment	TP53	1.96
70	Embryonal rhabdomyosarcoma	Enrichment	TP53	1.96
71	Hereditary angioedema with normal c1inh not related to f12 or plg variant	Enrichment	ANGPT1	1.96
72	Pseudomyogenic hemangioendothelioma	Enrichment	SERPINE1	1.96
73	Enchondromatosis, multiple, ollier type	Enrichment	HIF1A	1.87
74	Arrhythmogenic right ventricular dysplasia, familial, 1	Enrichment	TGFB3	1.87
75	Microcephaly 1, primary, autosomal recessive	Enrichment	ANGPT2	1.87
76	Rhabdomyosarcoma 2	Enrichment	TP53	1.87
77	Lymphoma	Enrichment	TP53	1.87
78	Arrhythmogenic right ventricular dysplasia 1	Enrichment	TGFB3	1.87
79	Acute megakaryocytic leukemia	Enrichment	TP53	1.87
80	Li-fraumeni syndrome	Enrichment	TP53	1.79
81	Adrenocortical carcinoma	Enrichment	TP53	1.79
82	Breast adenocarcinoma	Enrichment	TP53	1.79
83	Esophageal cancer	Enrichment	TP53	1.72
84	Squamous cell carcinoma, head and neck	Enrichment	TP53	1.72
85	Multiple enchondromatosis, maffucci type	Enrichment	HIF1A	1.72
86	Essential thrombocythemia	Enrichment	TP53	1.72
87	Gallbladder cancer	Enrichment	TP53	1.72
88	Paroxysmal dystonia	Enrichment	SLC2A1	1.72
89	B-lymphoblastic leukemia/lymphoma with t(9;22)(q34.1;q11.2)	Enrichment	TP53	1.72
90	Glioma susceptibility 1	Enrichment	TP53	1.67
91	Lymphoma, non-hodgkin, familial	Enrichment	TP53	1.67
92	Alternating hemiplegia of childhood	Enrichment	SLC2A1	1.67
93	Colorectal cancer	Enrichment	BAX, TP53	1.63
94	Myoclonic-atonic epilepsy	Enrichment	SLC2A1	1.61
95	Loeys-dietz syndrome	Enrichment	TGFB3	1.61
96	Adult hepatocellular carcinoma	Enrichment	TP53	1.61
97	Primary hyperaldosteronism	Enrichment	TP53	1.61
98	Leukemia, chronic lymphocytic	Enrichment	TP53	1.57
99	Familial colorectal cancer	Enrichment	TP53	1.57
100	Myelodysplastic syndrome	Enrichment	TP53	1.53
101	Inherited isolated arrhythmogenic ventricular dysplasia, biventricular variant	Enrichment	TGFB3	1.49
102	Inherited isolated arrhythmogenic cardiomyopathy, dominant-left variant	Enrichment	TGFB3	1.49
103	Lip and oral cavity carcinoma	Enrichment	TP53	1.49
104	Lung cancer susceptibility 3	Enrichment	TP53	1.43
105	Inherited isolated arrhythmogenic cardiomyopathy, dominant-right variant	Enrichment	TGFB3	1.43
106	Rhabdomyosarcoma	Enrichment	TP53	1.37
107	Gliosarcoma	Enrichment	TP53	1.37
108	Sudden infant death syndrome	Enrichment	PDHA1	1.34
109	Giant cell glioblastoma	Enrichment	TP53	1.34
110	Diffuse large b-cell lymphoma	Enrichment	TP53	1.30
111	Hepatoblastoma	Enrichment	TP53	1.25
112	Hepatocellular carcinoma	Enrichment	TP53	1.23
113	Tooth agenesis	Enrichment	TGFA	1.23
114	Diamond-blackfan anemia 1	Enrichment	TP53	1.22
115	Malaria	Enrichment	NOS2	1.22
116	Pancreatic cancer	Enrichment	TP53	1.18
117	Developmental and epileptic encephalopathy 1	Enrichment	SLC2A1	1.18
118	Strabismus	Enrichment	SLC2A1	1.15
119	Bladder cancer	Enrichment	TP53	1.12
120	Prostate cancer	Enrichment	TP53	1.12
121	Non-immune hydrops fetalis	Enrichment	ANGPT2	1.09
122	Primary autosomal recessive microcephaly	Enrichment	ANGPT2	1.08
123	Diamond-blackfan anemia	Enrichment	TP53	1.03
124	Leukemia, acute myeloid	Enrichment	TP53	0.98
125	Epilepsy	Enrichment	SLC2A1	0.98
126	Benign epilepsy with centrotemporal spikes	Enrichment	SLC2A1	0.97
127	Centralopathic epilepsy	Enrichment	SLC2A1	0.95
128	Gastric cancer	Enrichment	TP53	0.95
129	West syndrome	Enrichment	SLC2A1	0.95
130	Familial thoracic aortic aneurysm and aortic dissection	Enrichment	TGFB3	0.95
131	Hereditary breast carcinoma	Enrichment	TP53	0.95
132	Hereditary breast ovarian cancer syndrome	Enrichment	TP53	0.85
133	Myeloma, multiple	Enrichment	TP53	0.85
134	Breast cancer	Enrichment	TP53	0.73
135	Ovarian cancer	Enrichment	TP53	0.62
136	Autism spectrum disorder	Enrichment	HK1	0.59
137	Microcephaly	Enrichment	SLC2A1	0.54
138	Inherited cancer-predisposing syndrome	Enrichment	TP53	0.52
139	Retinitis pigmentosa	Enrichment	HK1	0.35
140	Hereditary retinal dystrophy	Enrichment	HK1	0.26
141	Fundus dystrophy	Enrichment	HK1	0.26

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Photodynamic therapy-induced HIF-1 survival signaling

Pathway Network for Photodynamic therapy-induced HIF-1 survival signaling

Member Pathways for Photodynamic therapy-induced HIF-1 survival signaling

Pathways in the Photodynamic therapy-induced HIF-1 survival signaling SuperPath

Associated Genes for Photodynamic therapy-induced HIF-1 survival signaling

Associated Disorders for Photodynamic therapy-induced HIF-1 survival signaling

Disorders associated with Photodynamic therapy-induced HIF-1 survival signaling SuperPath

STRING Interaction Network for Photodynamic therapy-induced HIF-1 survival signaling

Sources for Photodynamic therapy-induced HIF-1 survival signaling