Photodynamic therapy-induced unfolded protein response

No Pathway Network information available for Photodynamic therapy-induced unfolded protein response

Pathways in the Photodynamic therapy-induced unfolded protein response SuperPath

#	Name	Source	Genes
1	Photodynamic therapy-induced unfolded protein response	WikiPathways	ASNS ATF3 ATF4 ATF6 BBC3 BCL2L11 CALR DDIT3 DNAJB11 DNAJB9 DNAJC3 EDEM1 EIF2A EIF2AK3 ERN1 ERP27 HSP90B1 HSPA5 NARS1 NFE2L2 PDIA6 PPP1R15A SULT1E1 TRIB3 UBE2E1 WARS1 XBP1 (see all 27) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	EDEM1	ER Degradation Enhancing Alpha-Mannosidase Like Protein 1	Protein Coding	1
2	EIF2AK3	Eukaryotic Translation Initiation Factor 2 Alpha Kinase 3	Protein Coding	1
3	EIF2A	Eukaryotic Translation Initiation Factor 2A	Protein Coding	1
4	CALR	Calreticulin	Protein Coding	1
5	XBP1	X-Box Binding Protein 1	Protein Coding	1
6	WARS1	Tryptophanyl-TRNA Synthetase 1	Protein Coding	1
7	UBE2E1	Ubiquitin Conjugating Enzyme E2 E1	Protein Coding	1
8	HSP90B1	Heat Shock Protein 90 Beta Family Member 1	Protein Coding	1
9	SULT1E1	Sulfotransferase Family 1E Member 1	Protein Coding	1
10	TRIB3	Tribbles Pseudokinase 3	Protein Coding	1
11	DNAJC3	DnaJ Heat Shock Protein Family (Hsp40) Member C3	Protein Coding	1
12	NFE2L2	NFE2 Like BZIP Transcription Factor 2	Protein Coding	1
13	ATF4	Activating Transcription Factor 4	Protein Coding	1
14	ATF3	Activating Transcription Factor 3	Protein Coding	1
15	ASNS	Asparagine Synthetase (Glutamine-Hydrolyzing)	Protein Coding	1
16	DNAJB9	DnaJ Heat Shock Protein Family (Hsp40) Member B9	Protein Coding	1
17	HSPA5	Heat Shock Protein Family A (Hsp70) Member 5	Protein Coding	1
18	BBC3	BCL2 Binding Component 3	Protein Coding	1
19	PPP1R15A	Protein Phosphatase 1 Regulatory Subunit 15A	Protein Coding	1
20	ATF6	Activating Transcription Factor 6	Protein Coding	1
21	ERN1	Endoplasmic Reticulum To Nucleus Signaling 1	Protein Coding	1
22	DDIT3	DNA Damage Inducible Transcript 3	Protein Coding	1
23	BCL2L11	BCL2 Like 11	Protein Coding	1
24	ERP27	Endoplasmic Reticulum Protein 27	Protein Coding	1
25	PDIA6	Protein Disulfide Isomerase Family A Member 6	Protein Coding	1
26	DNAJB11	DnaJ Heat Shock Protein Family (Hsp40) Member B11	Protein Coding	1
27	NARS1	Asparaginyl-TRNA Synthetase 1	Protein Coding	1

Disorders associated with Photodynamic therapy-induced unfolded protein response SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Immunodeficiency, developmental delay, and hypohomocysteinemia	Enrichment	NFE2L2	2.70
2	Neurodevelopmental disorder with microcephaly, impaired language, and gait abnormalities	Enrichment	NARS1	2.70
3	Major affective disorder 7	Enrichment	XBP1	2.70
4	Achromatopsia 7	Enrichment	ATF6	2.70
5	Neurodevelopmental disorder with microcephaly, impaired language, epilepsy, and gait abnormalities	Enrichment	NARS1	2.70
6	Neuronopathy, distal hereditary motor, autosomal dominant 9	Enrichment	WARS1	2.70
7	Neurodevelopmental disorder with microcephaly and speech delay, with or without brain abnormalities	Enrichment	WARS1	2.70
8	Polycystic kidney disease 6 with or without polycystic liver disease	Enrichment	DNAJB11	2.70
9	Epiphyseal dysplasia, multiple, with early-onset diabetes mellitus	Enrichment	EIF2AK3	2.40
10	Ataxia, combined cerebellar and peripheral, with hearing loss and diabetes mellitus	Enrichment	DNAJC3	2.40
11	Thrombocythemia 1	Enrichment	CALR	2.22
12	Menkes disease	Enrichment	EIF2AK3	2.22
13	Asparagine synthetase deficiency	Enrichment	ASNS	2.22
14	Myxoid liposarcoma	Enrichment	DDIT3	2.22
15	Mitochondrial complex i deficiency, nuclear type 35	Enrichment	NARS1	2.22
16	Congenital microcephaly - severe encephalopathy - progressive cerebral atrophy syndrome	Enrichment	ASNS	2.22
17	Spinocerebellar ataxia, autosomal recessive 29	Enrichment	ASNS	2.22
18	Budd-chiari syndrome	Enrichment	CALR	2.10
19	Myelofibrosis	Enrichment	CALR	1.86
20	Essential thrombocythemia	Enrichment	CALR	1.86
21	Cystic kidney disease	Enrichment	DNAJB11	1.75
22	Achromatopsia	Enrichment	ATF6	1.70
23	Autosomal dominant polycystic kidney disease	Enrichment	DNAJB11	1.53
24	Polycystic kidney disease	Enrichment	DNAJB11	1.45
25	Lung cancer	Enrichment	NFE2L2	1.21
26	Primary autosomal recessive microcephaly	Enrichment	WARS1	1.21
27	Cone-rod dystrophy 2	Enrichment	ATF6	0.90
28	Colorectal cancer	Enrichment	NFE2L2	0.80
29	Complex neurodevelopmental disorder	Enrichment	WARS1	0.66
30	Hereditary retinal dystrophy	Enrichment	ATF6	0.35
31	Fundus dystrophy	Enrichment	ATF6	0.35

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Photodynamic therapy-induced unfolded protein response

Pathway Network for Photodynamic therapy-induced unfolded protein response

Member Pathways for Photodynamic therapy-induced unfolded protein response

Pathways in the Photodynamic therapy-induced unfolded protein response SuperPath

Associated Genes for Photodynamic therapy-induced unfolded protein response

Associated Disorders for Photodynamic therapy-induced unfolded protein response

Disorders associated with Photodynamic therapy-induced unfolded protein response SuperPath

STRING Interaction Network for Photodynamic therapy-induced unfolded protein response

Sources for Photodynamic therapy-induced unfolded protein response