PIP3 activates AKT signaling

Pathway network for the PIP3 activates AKT signaling SuperPath

Sources:

Reactome

Pathways in the PIP3 activates AKT signaling SuperPath

#	Name	Source	Genes
1	PIP3 activates AKT signaling	Reactome	ADRM1 AGO1 AGO2 AGO3 AGO4 AKT1 AKT1S1 AKT2 AKT3 AREG ATF2 ATN1 BAD BDNF BMI1 BTC CASP9 CBX2 CBX4 CBX6 CBX8 CD19 CD28 CD80 CD86 CDKN1A CDKN1B CHD3 CHD4 CHUK COMMD3-BMI1 CREB1 CSNK2A1 CSNK2A2 CSNK2B EED EGF EGFR EGR1 EPGN ERBB2 ERBB3 ERBB4 EREG ESR1 ESR2 EZH2 FGF1 FGF10 FGF16 FGF17 FGF18 FGF19 FGF2 FGF20 FGF22 FGF23 FGF3 FGF4 FGF5 FGF6 FGF7 FGF8 FGF9 FGFR1 FGFR2 FGFR3 FGFR4 FLT3 FLT3LG FOXO1 FOXO3 FOXO4 FRK FRS2 FYN GAB1 GAB2 GATAD2A GATAD2B GRB2 GSK3A GSK3B HBEGF HDAC1 HDAC2 HDAC3 HDAC5 HDAC7 HGF ICOS IER3 IL1RAP IL1RL1 IL33 INS INSR IRAK1 IRAK4 IRS1 IRS2 JUN KDM1A KIT KITLG KL KLB LAMTOR1 LAMTOR2 LAMTOR3 LAMTOR4 LAMTOR5 LCK MAF1 MAPK1 MAPK3 MAPKAP1 MBD3 MDM2 MECOM MET MKRN1 MLST8 MOV10 MTA1 MTA2 MTA3 MTOR MYD88 NEDD4 NR2E1 NR4A1 NRG1 NRG2 NRG3 NRG4 NTF3 NTF4 NTRK2 NTRK3 OTUD3 PDGFA PDGFB PDGFRA PDGFRB PDPK1 PHC1 PHC2 PHC3 PHLPP1 PHLPP2 PIK3AP1 PIK3CA PIK3CB PIK3CD PIK3CG PIK3R1 PIK3R2 PIK3R3 PIK3R5 PIK3R6 PIP4K2A PIP4K2B PIP4K2C PIP5K1A PIP5K1B PIP5K1C PML PPARG PPP2CA PPP2CB PPP2R1A PPP2R1B PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E PREX2 PRR5 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD6 PSMD7 PSMD8 PTEN PTPN11 RAC1 RAC2 RBBP4 RBBP7 RCOR1 REST RHEB RHOG RICTOR RING1 RNF146 RNF2 RPS27A RPS6KB2 RPTOR RRAGA RRAGB RRAGC RRAGD SALL4 SCMH1 SEM1 SGK1 SLC38A9 SNAI1 SNAI2 SRC STRN STUB1 SUZ12 TGFA THEM4 TNKS TNKS2 TNRC6A TNRC6B TNRC6C TP53 TRAF6 TRAT1 TRIB3 TRIM27 TSC2 UBA52 UBB UBC USP13 USP7 VAV1 WWP2 (see all 262) (see less)
2	Diseases of signal transduction by growth factor receptors and second messengers	Reactome	ACTB ACTG1 ADAM10 ADAM17 ADRM1 AGGF1 AGK AGO1 AGO2 AGO3 AGO4 AGTRAP AKAP9 AKT1 AKT1S1 AKT2 AKT3 ALK AMER1 AP3B1 APBB1IP APC APH1A APH1B ARAF AREG ARRB1 ARRB2 ATG7 ATIC AXIN1 BAD BCL11A BCL2A1 BCL2L1 BCL2L11 BCR BDNF BIN2 BIRC6 BRAF BRAP BTC CALM1 CALM2 CALM3 CAMK2A CAMK2B CAMK2D CAMK2G CARS1 CASP9 CBL CCNB1 CCNC CD19 CD28 CD80 CD86 CDC37 CDK8 CDKN1A CDKN1B CEBPB CEP43 CHUK CLCN6 CLIP1 CLTC CNKSR1 CNKSR2 CNTRL CPSF6 CREB1 CREBBP CSK CSNK1A1 CTBP1 CTBP2 CTNNB1 CUL1 CUX1 DCTN1 DERL2 DHH DKK1 DKK2 DKK4 DLL1 DLL4 DNMT1 DUSP10 DUSP16 DUSP6 DUSP7 DUSP8 DUSP9 EEF1G EGF EGFR EIF2AK3 EML4 EP300 EPGN ERBB2 ERBB3 ERBB4 ERBIN EREG ERLEC1 ERLIN2 ESR1 ESR2 ESRP1 ETV6 FAM114A2 FAM131B FBXW7 FGA FGB FGF1 FGF10 FGF16 FGF17 FGF18 FGF19 FGF2 FGF20 FGF22 FGF23 FGF3 FGF4 FGF5 FGF6 FGF7 FGF8 FGF9 FGFR1 FGFR1OP2 FGFR2 FGFR3 FGFR4 FGG FIP1L1 FKBP1A FLT3 FLT3LG FN1 FOXM1 FOXO1 FOXO3 FOXO4 FRS2 FRS3 FXR1 FYN FZD4 FZD5 FZD6 FZD8 GAB1 GAB2 GCC2 GOLGA4 GOLGB1 GRB2 GSK3A GSK3B GTF2F1 GTF2F2 HBEGF HDAC1 HDAC10 HDAC11 HDAC2 HDAC3 HDAC4 HDAC5 HDAC6 HDAC7 HDAC8 HDAC9 HES1 HES5 HEY1 HEY2 HEYL HGF HHAT HIP1 HRAS HSP90AA1 ICOS IHH IL10 IL10RA IL22 IQGAP1 IRF4 IRS1 IRS2 ITGA2B ITGB3 JAG1 JAG2 JAK2 JUN JUNB KANK1 KAT2A KAT2B KDM7A KDR KIAA1549 KIF5B KIT KITLG KL KLB KLC1 KRAS KREMEN1 KREMEN2 KSR1 KSR2 LCK LMNA LMO7 LRP5 LRP6 LRRFIP1 LYN MAML1 MAML2 MAML3 MAMLD1 MAP2K1 MAP2K2 MAP3K11 MAPK1 MAPK3 MAPK8 MAPK9 MAPKAP1 MARK3 MCL1 MDM2 MECP2 MET MIB1 MIB2 MLST8 MOV10 MPRIP MRAS MSN MTOR MYC MYH9 MYO18A NCBP1 NCBP2 NCOR1 NCOR2 NCSTN NEURL1 NEURL1B NF1 NOTCH1 NOX4 NPM1 NR4A1 NRAS NRG1 NRG2 NRG3 NRG4 NTF3 NTF4 NTRK2 NTRK3 OS9 PAPSS1 PDGFA PDGFB PDGFRA PDGFRB PDPK1 PEBP1 PHB1 PIK3AP1 PIK3CA PIK3CB PIK3CD PIK3CG PIK3R1 PIK3R2 PIK3R3 PIK3R5 PIK3R6 PIM1 PLCG1 POLR2A POLR2B POLR2C POLR2D POLR2E POLR2F POLR2G POLR2H POLR2I POLR2J POLR2K POLR2L PORCN PPFIBP1 PPM1B PPP1CB PPP1CC PPP2CA PPP2CB PPP2R1A PPP2R1B PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E PRF1 PRKAR1A PRR5 PSEN1 PSEN2 PSENEN PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD6 PSMD7 PSMD8 PTEN PTPN11 PTPN12 PTPN6 QKI RAC1 RAC2 RAF1 RANBP2 RAP1A RAP1B RB1 RBPJ RBX1 RHOG RICTOR RNF213 RNF43 RPS27A RPS6 RPS6KB2 RRBP1 SEC31A SEL1L SEM1 SHC1 SHH SHOC2 SKP1 SMAD2 SMAD3 SMAD4 SND1 SNW1 SOS1 SPRED1 SPRED2 SPRED3 SPTBN1 SQSTM1 SRC STAT1 STAT3 STAT5A STAT5B STRN SYVN1 TBL1X TBL1XR1 TCF7L2 TENT4A TFG TGFA TGFB1 TGFBR1 TGFBR2 TLN1 TNKS TNKS2 TNRC6C TP53 TPM3 TPM4 TPR TRAK1 TRAT1 TRIM24 TRIP11 TSC2 TWIST1 TYK2 UBA52 UBB UBC VAV1 VCL VCP VWF WDCP WDR48 WNT3A YES1 YWHAB ZAP70 ZC3HAV1 ZC3HC1 ZFYVE9 ZMYM2 (see all 452) (see less)
3	Intracellular signaling by second messengers	Reactome	ADCY1 ADCY2 ADCY3 ADCY4 ADCY5 ADCY6 ADCY7 ADCY8 ADCY9 ADRM1 AGO1 AGO2 AGO3 AGO4 AHCYL1 AKT1 AKT1S1 AKT2 AKT3 AREG ATF2 ATN1 BAD BDNF BMI1 BTC CALM1 CALM2 CALM3 CAMK2A CAMK2B CAMK2D CAMK2G CAMK4 CAMKK1 CAMKK2 CASP9 CBX2 CBX4 CBX6 CBX8 CD19 CD28 CD80 CD86 CDKN1A CDKN1B CHD3 CHD4 CHUK COMMD3-BMI1 CREB1 CSNK2A1 CSNK2A2 CSNK2B EED EGF EGFR EGR1 EPGN ERBB2 ERBB3 ERBB4 EREG ESR1 ESR2 EZH2 FGF1 FGF10 FGF16 FGF17 FGF18 FGF19 FGF2 FGF20 FGF22 FGF23 FGF3 FGF4 FGF5 FGF6 FGF7 FGF8 FGF9 FGFR1 FGFR2 FGFR3 FGFR4 FLT3 FLT3LG FOXO1 FOXO3 FOXO4 FRK FRS2 FYN GAB1 GAB2 GATAD2A GATAD2B GRB2 GRK2 GSK3A GSK3B HBEGF HDAC1 HDAC2 HDAC3 HDAC5 HDAC7 HGF ICOS IER3 IL1RAP IL1RL1 IL33 INS INSR IRAK1 IRAK4 IRS1 IRS2 ITPR1 ITPR2 ITPR3 JUN KDM1A KIT KITLG KL KLB KPNA2 LAMTOR1 LAMTOR2 LAMTOR3 LAMTOR4 LAMTOR5 LCK MAF1 MAPK1 MAPK3 MAPKAP1 MBD3 MDM2 MECOM MET MKRN1 MLST8 MOV10 MTA1 MTA2 MTA3 MTOR MYD88 NBEA NEDD4 NR2E1 NR4A1 NRG1 NRG2 NRG3 NRG4 NTF3 NTF4 NTRK2 NTRK3 OTUD3 PDE1A PDE1B PDE1C PDGFA PDGFB PDGFRA PDGFRB PDPK1 PHC1 PHC2 PHC3 PHLPP1 PHLPP2 PIK3AP1 PIK3CA PIK3CB PIK3CD PIK3CG PIK3R1 PIK3R2 PIK3R3 PIK3R5 PIK3R6 PIP4K2A PIP4K2B PIP4K2C PIP5K1A PIP5K1B PIP5K1C PLCG1 PML PPARG PPP2CA PPP2CB PPP2R1A PPP2R1B PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E PREX2 PRKACA PRKACB PRKACG PRKAR1A PRKAR1B PRKAR2A PRKAR2B PRKCA PRKCD PRKCE PRKCG PRKX PRR5 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD6 PSMD7 PSMD8 PTEN PTPN11 RAC1 RAC2 RBBP4 RBBP7 RCOR1 REST RHEB RHOG RICTOR RING1 RNF146 RNF2 RPS27A RPS6KB2 RPTOR RRAGA RRAGB RRAGC RRAGD SALL4 SCMH1 SEM1 SGK1 SLC38A9 SNAI1 SNAI2 SRC STRN STUB1 SUZ12 TGFA THEM4 TNKS TNKS2 TNRC6A TNRC6B TNRC6C TP53 TRAF6 TRAT1 TRIB3 TRIM27 TSC2 UBA52 UBB UBC USP13 USP7 VAV1 WWP2 (see all 304) (see less)

Gene overlap in member pathways for PIP3 activates AKT signaling SuperPath

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	AKT3	AKT Serine/Threonine Kinase 3	Protein Coding	3
2	HDAC5	Histone Deacetylase 5	Protein Coding	3
3	PSMD14	Proteasome 26S Subunit, Non-ATPase 14	Protein Coding	3
4	CDKN1A	Cyclin Dependent Kinase Inhibitor 1A	Protein Coding	3
5	CDKN1B	Cyclin Dependent Kinase Inhibitor 1B	Protein Coding	3
6	NRG3	Neuregulin 3	Protein Coding	3
7	FRS2	Fibroblast Growth Factor Receptor Substrate 2	Protein Coding	3
8	ADRM1	ADRM1 26S Proteasome Ubiquitin Receptor	Protein Coding	3
9	CHUK	Component Of Inhibitor Of Nuclear Factor Kappa B Kinase Complex	Protein Coding	3
10	PIK3AP1	Phosphoinositide-3-Kinase Adaptor Protein 1	Protein Coding	3
11	CREB1	CAMP Responsive Element Binding Protein 1	Protein Coding	3
12	NRG4	Neuregulin 4	Protein Coding	3
13	PIK3R6	Phosphoinositide-3-Kinase Regulatory Subunit 6	Protein Coding	3
14	KLB	Klotho Beta	Protein Coding	3
15	HBEGF	Heparin Binding EGF Like Growth Factor	Protein Coding	3
16	AGO3	Argonaute RISC Catalytic Component 3	Protein Coding	3
17	AGO4	Argonaute RISC Component 4	Protein Coding	3
18	EGF	Epidermal Growth Factor	Protein Coding	3
19	EGFR	Epidermal Growth Factor Receptor	Protein Coding	3
20	ERBB2	Erb-B2 Receptor Tyrosine Kinase 2	Protein Coding	3
21	ERBB3	Erb-B2 Receptor Tyrosine Kinase 3	Protein Coding	3
22	ERBB4	Erb-B2 Receptor Tyrosine Kinase 4	Protein Coding	3
23	EREG	Epiregulin	Protein Coding	3
24	AKT1	AKT Serine/Threonine Kinase 1	Protein Coding	3
25	AKT2	AKT Serine/Threonine Kinase 2	Protein Coding	3
26	ESR1	Estrogen Receptor 1	Protein Coding	3
27	ESR2	Estrogen Receptor 2	Protein Coding	3
28	FGF1	Fibroblast Growth Factor 1	Protein Coding	3
29	FGF2	Fibroblast Growth Factor 2	Protein Coding	3
30	FGF3	Fibroblast Growth Factor 3	Protein Coding	3
31	FGF4	Fibroblast Growth Factor 4	Protein Coding	3
32	FGF5	Fibroblast Growth Factor 5	Protein Coding	3
33	FGF6	Fibroblast Growth Factor 6	Protein Coding	3
34	FGF7	Fibroblast Growth Factor 7	Protein Coding	3
35	FGF8	Fibroblast Growth Factor 8	Protein Coding	3
36	FGF9	Fibroblast Growth Factor 9	Protein Coding	3
37	FGF10	Fibroblast Growth Factor 10	Protein Coding	3
38	FGFR1	Fibroblast Growth Factor Receptor 1	Protein Coding	3
39	FGFR3	Fibroblast Growth Factor Receptor 3	Protein Coding	3
40	FGFR2	Fibroblast Growth Factor Receptor 2	Protein Coding	3
41	FGFR4	Fibroblast Growth Factor Receptor 4	Protein Coding	3
42	FOXO1	Forkhead Box O1	Protein Coding	3
43	FOXO3	Forkhead Box O3	Protein Coding	3
44	FLT3	Fms Related Receptor Tyrosine Kinase 3	Protein Coding	3
45	FLT3LG	Fms Related Receptor Tyrosine Kinase 3 Ligand	Protein Coding	3
46	PIK3R5	Phosphoinositide-3-Kinase Regulatory Subunit 5	Protein Coding	3
47	MTOR	Mechanistic Target Of Rapamycin Kinase	Protein Coding	3
48	RICTOR	RPTOR Independent Companion Of MTOR Complex 2	Protein Coding	3
49	FYN	FYN Proto-Oncogene, Src Family Tyrosine Kinase	Protein Coding	3
50	GAB1	GRB2 Associated Binding Protein 1	Protein Coding	3
51	EPGN	Epithelial Mitogen	Protein Coding	3
52	FGF20	Fibroblast Growth Factor 20	Protein Coding	3
53	AGO1	Argonaute RISC Component 1	Protein Coding	3
54	FGF22	Fibroblast Growth Factor 22	Protein Coding	3
55	AGO2	Argonaute RISC Catalytic Component 2	Protein Coding	3
56	GRB2	Growth Factor Receptor Bound Protein 2	Protein Coding	3
57	GSK3A	Glycogen Synthase Kinase 3 Alpha	Protein Coding	3
58	GSK3B	Glycogen Synthase Kinase 3 Beta	Protein Coding	3
59	ICOS	Inducible T Cell Costimulator	Protein Coding	3
60	HDAC1	Histone Deacetylase 1	Protein Coding	3
61	HDAC2	Histone Deacetylase 2	Protein Coding	3
62	HGF	Hepatocyte Growth Factor	Protein Coding	3
63	NRG1	Neuregulin 1	Protein Coding	3
64	NR4A1	Nuclear Receptor Subfamily 4 Group A Member 1	Protein Coding	3
65	IRS1	Insulin Receptor Substrate 1	Protein Coding	3
66	JUN	Jun Proto-Oncogene, AP-1 Transcription Factor Subunit	Protein Coding	3
67	AREG	Amphiregulin	Protein Coding	3
68	KIT	KIT Proto-Oncogene, Receptor Tyrosine Kinase	Protein Coding	3
69	RHOG	Ras Homolog Family Member G	Protein Coding	3
70	LCK	LCK Proto-Oncogene, Src Family Tyrosine Kinase	Protein Coding	3
71	MDM2	MDM2 Proto-Oncogene	Protein Coding	3
72	MET	MET Proto-Oncogene, Receptor Tyrosine Kinase	Protein Coding	3
73	KITLG	KIT Ligand	Protein Coding	3
74	FOXO4	Forkhead Box O4	Protein Coding	3
75	MOV10	Mov10 RNA Helicase	Protein Coding	3
76	NTF3	Neurotrophin 3	Protein Coding	3
77	NTF4	Neurotrophin 4	Protein Coding	3
78	NTRK2	Neurotrophic Receptor Tyrosine Kinase 2	Protein Coding	3
79	NTRK3	Neurotrophic Receptor Tyrosine Kinase 3	Protein Coding	3
80	TRAT1	T Cell Receptor Associated Transmembrane Adaptor 1	Protein Coding	3
81	PDGFA	Platelet Derived Growth Factor Subunit A	Protein Coding	3
82	PDGFB	Platelet Derived Growth Factor Subunit B	Protein Coding	3
83	PDGFRA	Platelet Derived Growth Factor Receptor Alpha	Protein Coding	3
84	HDAC7	Histone Deacetylase 7	Protein Coding	3
85	PDGFRB	Platelet Derived Growth Factor Receptor Beta	Protein Coding	3
86	PDPK1	3-Phosphoinositide Dependent Protein Kinase 1	Protein Coding	3
87	PIK3CA	Phosphatidylinositol-4,5-Bisphosphate 3-Kinase Catalytic Subunit Alpha	Protein Coding	3
88	PIK3CB	Phosphatidylinositol-4,5-Bisphosphate 3-Kinase Catalytic Subunit Beta	Protein Coding	3
89	PIK3CD	Phosphatidylinositol-4,5-Bisphosphate 3-Kinase Catalytic Subunit Delta	Protein Coding	3
90	PIK3CG	Phosphatidylinositol-4,5-Bisphosphate 3-Kinase Catalytic Subunit Gamma	Protein Coding	3
91	PIK3R1	Phosphoinositide-3-Kinase Regulatory Subunit 1	Protein Coding	3
92	PIK3R2	Phosphoinositide-3-Kinase Regulatory Subunit 2	Protein Coding	3
93	PPP2CA	Protein Phosphatase 2 Catalytic Subunit Alpha	Protein Coding	3
94	PPP2CB	Protein Phosphatase 2 Catalytic Subunit Beta	Protein Coding	3
95	PPP2R1A	Protein Phosphatase 2 Scaffold Subunit Aalpha	Protein Coding	3
96	PPP2R1B	Protein Phosphatase 2 Scaffold Subunit Abeta	Protein Coding	3
97	PPP2R5A	Protein Phosphatase 2 Regulatory Subunit B''Alpha	Protein Coding	3
98	PPP2R5B	Protein Phosphatase 2 Regulatory Subunit B''Beta	Protein Coding	3
99	PPP2R5C	Protein Phosphatase 2 Regulatory Subunit B''Gamma	Protein Coding	3
100	PPP2R5D	Protein Phosphatase 2 Regulatory Subunit B''Delta	Protein Coding	3
101	PPP2R5E	Protein Phosphatase 2 Regulatory Subunit B''Epsilon	Protein Coding	3
102	PRR5	Proline Rich 5	Protein Coding	3
103	MAPK1	Mitogen-Activated Protein Kinase 1	Protein Coding	3
104	MAPK3	Mitogen-Activated Protein Kinase 3	Protein Coding	3
105	PSMA1	Proteasome 20S Subunit Alpha 1	Protein Coding	3
106	PSMA2	Proteasome 20S Subunit Alpha 2	Protein Coding	3
107	PSMA3	Proteasome 20S Subunit Alpha 3	Protein Coding	3
108	PSMA4	Proteasome 20S Subunit Alpha 4	Protein Coding	3
109	PSMA5	Proteasome 20S Subunit Alpha 5	Protein Coding	3
110	PSMA6	Proteasome 20S Subunit Alpha 6	Protein Coding	3
111	PSMA7	Proteasome 20S Subunit Alpha 7	Protein Coding	3
112	PSMB1	Proteasome 20S Subunit Beta 1	Protein Coding	3
113	PSMB2	Proteasome 20S Subunit Beta 2	Protein Coding	3
114	PSMB3	Proteasome 20S Subunit Beta 3	Protein Coding	3
115	PSMB4	Proteasome 20S Subunit Beta 4	Protein Coding	3
116	PSMB5	Proteasome 20S Subunit Beta 5	Protein Coding	3
117	PSMB6	Proteasome 20S Subunit Beta 6	Protein Coding	3
118	PSMB7	Proteasome 20S Subunit Beta 7	Protein Coding	3
119	PSMC1	Proteasome 26S Subunit, ATPase 1	Protein Coding	3
120	PSMC2	Proteasome 26S Subunit, ATPase 2	Protein Coding	3
121	PSMC3	Proteasome 26S Subunit, ATPase 3	Protein Coding	3
122	PSMC4	Proteasome 26S Subunit, ATPase 4	Protein Coding	3
123	PSMC5	Proteasome 26S Subunit, ATPase 5	Protein Coding	3
124	PSMC6	Proteasome 26S Subunit, ATPase 6	Protein Coding	3
125	PSMD1	Proteasome 26S Subunit, Non-ATPase 1	Protein Coding	3
126	PSMD2	Proteasome 26S Subunit Ubiquitin Receptor, Non-ATPase 2	Protein Coding	3
127	PSMD3	Proteasome 26S Subunit, Non-ATPase 3	Protein Coding	3
128	PSMD7	Proteasome 26S Subunit, Non-ATPase 7	Protein Coding	3
129	PSMD8	Proteasome 26S Subunit, Non-ATPase 8	Protein Coding	3
130	PSMD11	Proteasome 26S Subunit, Non-ATPase 11	Protein Coding	3
131	PSMD12	Proteasome 26S Subunit, Non-ATPase 12	Protein Coding	3
132	PSMD13	Proteasome 26S Subunit, Non-ATPase 13	Protein Coding	3
133	BAD	BCL2 Associated Agonist Of Cell Death	Protein Coding	3
134	PTEN	Phosphatase And Tensin Homolog	Protein Coding	3
135	TNRC6C	Trinucleotide Repeat Containing Adaptor 6C	Protein Coding	3
136	PTPN11	Protein Tyrosine Phosphatase Non-Receptor Type 11	Protein Coding	3
137	RAC1	Rac Family Small GTPase 1	Protein Coding	3
138	RAC2	Rac Family Small GTPase 2	Protein Coding	3
139	RPS6KB2	Ribosomal Protein S6 Kinase B2	Protein Coding	3
140	RPS27A	Ribosomal Protein S27a	Protein Coding	3
141	BDNF	Brain Derived Neurotrophic Factor	Protein Coding	3
142	MLST8	MTOR Associated Protein MLST8	Protein Coding	3
143	SRC	SRC Proto-Oncogene, Non-Receptor Tyrosine Kinase	Protein Coding	3
144	STRN	Striatin	Protein Coding	3
145	BTC	Betacellulin	Protein Coding	3
146	TGFA	Transforming Growth Factor Alpha	Protein Coding	3
147	TP53	Tumor Protein P53	Protein Coding	3
148	TSC2	TSC Complex Subunit 2	Protein Coding	3
149	UBA52	Ubiquitin A-52 Residue Ribosomal Protein Fusion Product 1	Protein Coding	3
150	UBB	Ubiquitin B	Protein Coding	3
151	UBC	Ubiquitin C	Protein Coding	3
152	VAV1	Vav Guanine Nucleotide Exchange Factor 1	Protein Coding	3
153	MAPKAP1	MAPK Associated Protein 1	Protein Coding	3
154	SEM1	SEM1 26S Proteasome Subunit	Protein Coding	3
155	TNKS2	Tankyrase 2	Protein Coding	3
156	FGF23	Fibroblast Growth Factor 23	Protein Coding	3
157	CASP9	Caspase 9	Protein Coding	3
158	AKT1S1	AKT1 Substrate 1	Protein Coding	3
159	PIK3R3	Phosphoinositide-3-Kinase Regulatory Subunit 3	Protein Coding	3
160	TNKS	Tankyrase	Protein Coding	3
161	IRS2	Insulin Receptor Substrate 2	Protein Coding	3
162	FGF18	Fibroblast Growth Factor 18	Protein Coding	3
163	FGF17	Fibroblast Growth Factor 17	Protein Coding	3
164	FGF16	Fibroblast Growth Factor 16	Protein Coding	3
165	HDAC3	Histone Deacetylase 3	Protein Coding	3
166	CD19	CD19 Molecule	Protein Coding	3
167	KL	Klotho	Protein Coding	3
168	CD28	CD28 Molecule	Protein Coding	3
169	CD80	CD80 Molecule	Protein Coding	3
170	CD86	CD86 Molecule	Protein Coding	3
171	NRG2	Neuregulin 2	Protein Coding	3
172	GAB2	GRB2 Associated Binding Protein 2	Protein Coding	3
173	PSMD6	Proteasome 26S Subunit, Non-ATPase 6	Protein Coding	3
174	FGF19	Fibroblast Growth Factor 19	Protein Coding	3
175	COMMD3-BMI1	COMMD3-BMI1 Readthrough	Protein Coding	2
176	STUB1	STIP1 Homology And U-Box Containing Protein 1	Protein Coding	2
177	RRAGB	Ras Related GTP Binding B	Protein Coding	2
178	LAMTOR5	Late Endosomal/Lysosomal Adaptor, MAPK And MTOR Activator 5	Protein Coding	2
179	RRAGA	Ras Related GTP Binding A	Protein Coding	2
180	WWP2	WW Domain Containing E3 Ubiquitin Protein Ligase 2	Protein Coding	2
181	CHD3	Chromodomain Helicase DNA Binding Protein 3	Protein Coding	2
182	CHD4	Chromodomain Helicase DNA Binding Protein 4	Protein Coding	2
183	THEM4	Thioesterase Superfamily Member 4	Protein Coding	2
184	ATF2	Activating Transcription Factor 2	Protein Coding	2
185	CSNK2A1	Casein Kinase 2 Alpha 1	Protein Coding	2
186	CSNK2A2	Casein Kinase 2 Alpha 2	Protein Coding	2
187	CSNK2B	Casein Kinase 2 Beta	Protein Coding	2
188	SLC38A9	Solute Carrier Family 38 Member 9	Protein Coding	2
189	ATN1	Atrophin 1	Protein Coding	2
190	PHC1	Polyhomeotic Homolog 1	Protein Coding	2
191	PHC2	Polyhomeotic Homolog 2	Protein Coding	2
192	EGR1	Early Growth Response 1	Protein Coding	2
193	MECOM	MDS1 And EVI1 Complex Locus	Protein Coding	2
194	EZH2	Enhancer Of Zeste 2 Polycomb Repressive Complex 2 Subunit	Protein Coding	2
195	SCMH1	Scm Polycomb Group Protein Homolog 1	Protein Coding	2
196	KDM1A	Lysine Demethylase 1A	Protein Coding	2
197	PHLPP2	PH Domain And Leucine Rich Repeat Protein Phosphatase 2	Protein Coding	2
198	TNRC6B	Trinucleotide Repeat Containing Adaptor 6B	Protein Coding	2
199	RCOR1	REST Corepressor 1	Protein Coding	2
200	PHLPP1	PH Domain And Leucine Rich Repeat Protein Phosphatase 1	Protein Coding	2
201	OTUD3	OTU Deubiquitinase 3	Protein Coding	2
202	PIP5K1C	Phosphatidylinositol-4-Phosphate 5-Kinase Type 1 Gamma	Protein Coding	2
203	CBX6	Chromobox 6	Protein Coding	2
204	SUZ12	SUZ12 Polycomb Repressive Complex 2 Subunit	Protein Coding	2
205	MKRN1	Makorin Ring Finger Protein 1	Protein Coding	2
206	FRK	Fyn Related Src Family Tyrosine Kinase	Protein Coding	2
207	TNRC6A	Trinucleotide Repeat Containing Adaptor 6A	Protein Coding	2
208	LAMTOR2	Late Endosomal/Lysosomal Adaptor, MAPK And MTOR Activator 2	Protein Coding	2
209	IL1RAP	Interleukin 1 Receptor Accessory Protein	Protein Coding	2
210	INS	Insulin	Protein Coding	2
211	INSR	Insulin Receptor	Protein Coding	2
212	IRAK1	Interleukin 1 Receptor Associated Kinase 1	Protein Coding	2
213	LAMTOR4	Late Endosomal/Lysosomal Adaptor, MAPK And MTOR Activator 4	Protein Coding	2
214	MYD88	MYD88 Innate Immune Signal Transduction Adaptor	Protein Coding	2
215	NEDD4	NEDD4 E3 Ubiquitin Protein Ligase	Protein Coding	2
216	IRAK4	Interleukin 1 Receptor Associated Kinase 4	Protein Coding	2
217	PIP4K2A	Phosphatidylinositol-5-Phosphate 4-Kinase Type 2 Alpha	Protein Coding	2
218	MBD3	Methyl-CpG Binding Domain Protein 3	Protein Coding	2
219	PML	PML Nuclear Body Scaffold	Protein Coding	2
220	PPARG	Peroxisome Proliferator Activated Receptor Gamma	Protein Coding	2
221	GATAD2A	GATA Zinc Finger Domain Containing 2A	Protein Coding	2
222	LAMTOR1	Late Endosomal/Lysosomal Adaptor, MAPK And MTOR Activator 1	Protein Coding	2
223	SALL4	Spalt Like Transcription Factor 4	Protein Coding	2
224	CBX8	Chromobox 8	Protein Coding	2
225	GATAD2B	GATA Zinc Finger Domain Containing 2B	Protein Coding	2
226	MTA3	Metastasis Associated 1 Family Member 3	Protein Coding	2
227	RPTOR	Regulatory Associated Protein Of MTOR Complex 1	Protein Coding	2
228	TRIB3	Tribbles Pseudokinase 3	Protein Coding	2
229	RRAGD	Ras Related GTP Binding D	Protein Coding	2
230	RBBP4	RB Binding Protein 4, Chromatin Remodeling Factor	Protein Coding	2
231	RBBP7	RB Binding Protein 7, Chromatin Remodeling Factor	Protein Coding	2
232	REST	RE1 Silencing Transcription Factor	Protein Coding	2
233	TRIM27	Tripartite Motif Containing 27	Protein Coding	2
234	RHEB	Ras Homolog, MTORC1 Binding	Protein Coding	2
235	RING1	Ring Finger Protein 1	Protein Coding	2
236	RNF2	Ring Finger Protein 2	Protein Coding	2
237	RRAGC	Ras Related GTP Binding C	Protein Coding	2
238	SGK1	Serum/Glucocorticoid Regulated Kinase 1	Protein Coding	2
239	BMI1	BMI1 Proto-Oncogene, Polycomb Ring Finger	Protein Coding	2
240	SNAI2	Snail Family Transcriptional Repressor 2	Protein Coding	2
241	SNAI1	Snail Family Transcriptional Repressor 1	Protein Coding	2
242	NR2E1	Nuclear Receptor Subfamily 2 Group E Member 1	Protein Coding	2
243	TRAF6	TNF Receptor Associated Factor 6	Protein Coding	2
244	USP7	Ubiquitin Specific Peptidase 7	Protein Coding	2
245	PIP4K2C	Phosphatidylinositol-5-Phosphate 4-Kinase Type 2 Gamma	Protein Coding	2
246	PHC3	Polyhomeotic Homolog 3	Protein Coding	2
247	PREX2	Phosphatidylinositol-3,4,5-Trisphosphate Dependent Rac Exchange Factor 2	Protein Coding	2
248	RNF146	Ring Finger Protein 146	Protein Coding	2
249	PIP5K1A	Phosphatidylinositol-4-Phosphate 5-Kinase Type 1 Alpha	Protein Coding	2
250	PIP5K1B	Phosphatidylinositol-4-Phosphate 5-Kinase Type 1 Beta	Protein Coding	2
251	PIP4K2B	Phosphatidylinositol-5-Phosphate 4-Kinase Type 2 Beta	Protein Coding	2
252	MAF1	MAF1 Negative Regulator Of RNA Polymerase III	Protein Coding	2
253	CBX2	Chromobox 2	Protein Coding	2
254	CBX4	Chromobox 4	Protein Coding	2
255	LAMTOR3	Late Endosomal/Lysosomal Adaptor, MAPK And MTOR Activator 3	Protein Coding	2
256	EED	Embryonic Ectoderm Development	Protein Coding	2
257	IER3	Immediate Early Response 3	Protein Coding	2
258	USP13	Ubiquitin Specific Peptidase 13	Protein Coding	2
259	IL33	Interleukin 33	Protein Coding	2
260	MTA1	Metastasis Associated 1	Protein Coding	2
261	IL1RL1	Interleukin 1 Receptor Like 1	Protein Coding	2
262	MTA2	Metastasis Associated 1 Family Member 2	Protein Coding	2
263	PLCG1	Phospholipase C Gamma 1	Protein Coding	2
264	PRKAR1A	Protein Kinase CAMP-Dependent Type I Regulatory Subunit Alpha	Protein Coding	2
265	CALM1	Calmodulin 1	Protein Coding	2
266	CALM2	Calmodulin 2	Protein Coding	2
267	CALM3	Calmodulin 3	Protein Coding	2
268	CAMK2A	Calcium/Calmodulin Dependent Protein Kinase II Alpha	Protein Coding	2
269	CAMK2B	Calcium/Calmodulin Dependent Protein Kinase II Beta	Protein Coding	2
270	CAMK2D	Calcium/Calmodulin Dependent Protein Kinase II Delta	Protein Coding	2
271	CAMK2G	Calcium/Calmodulin Dependent Protein Kinase II Gamma	Protein Coding	2
272	HDAC6	Histone Deacetylase 6	Protein Coding	1
273	BCL2L11	BCL2 Like 11	Protein Coding	1
274	MAMLD1	Mastermind Like Domain Containing 1	Protein Coding	1
275	AKAP9	A-Kinase Anchoring Protein 9	Protein Coding	1
276	ADAM10	ADAM Metallopeptidase Domain 10	Protein Coding	1
277	CDK8	Cyclin Dependent Kinase 8	Protein Coding	1
278	CNKSR1	Connector Enhancer Of Kinase Suppressor Of Ras 1	Protein Coding	1
279	TFG	Trafficking From ER To Golgi Regulator	Protein Coding	1
280	CEBPB	CCAAT Enhancer Binding Protein Beta	Protein Coding	1
281	ATG7	Autophagy Related 7	Protein Coding	1
282	FRS3	Fibroblast Growth Factor Receptor Substrate 3	Protein Coding	1
283	FAM114A2	Family With Sequence Similarity 114 Member A2	Protein Coding	1
284	OS9	OS9 Endoplasmic Reticulum Lectin	Protein Coding	1
285	TENT4A	Terminal Nucleotidyltransferase 4A	Protein Coding	1
286	CPSF6	Cleavage And Polyadenylation Specific Factor 6	Protein Coding	1
287	CNTRL	Centriolin	Protein Coding	1
288	CEP43	Centrosomal Protein 43	Protein Coding	1
289	CDC37	Cell Division Cycle 37, HSP90 Cochaperone	Protein Coding	1
290	ERLIN2	ER Lipid Raft Associated 2	Protein Coding	1
291	DUSP10	Dual Specificity Phosphatase 10	Protein Coding	1
292	CLCN6	Chloride Voltage-Gated Channel 6	Protein Coding	1
293	CLTC	Clathrin Heavy Chain	Protein Coding	1
294	CREBBP	CREB Binding Lysine Acetyltransferase	Protein Coding	1
295	AMER1	APC Membrane Recruitment Protein 1	Protein Coding	1
296	MIB2	MIB E3 Ubiquitin Protein Ligase 2	Protein Coding	1
297	CSK	C-Terminal Src Kinase	Protein Coding	1
298	CSNK1A1	Casein Kinase 1 Alpha 1	Protein Coding	1
299	CTBP1	C-Terminal Binding Protein 1	Protein Coding	1
300	CTBP2	C-Terminal Binding Protein 2	Protein Coding	1
301	CTNNB1	Catenin Beta 1	Protein Coding	1
302	CUX1	Cut Like Homeobox 1	Protein Coding	1
303	SPRED1	Sprouty Related EVH1 Domain Containing 1	Protein Coding	1
304	DCTN1	Dynactin Subunit 1	Protein Coding	1
305	DNMT1	DNA Methyltransferase 1	Protein Coding	1
306	JAG1	Jagged Canonical Notch Ligand 1	Protein Coding	1
307	DUSP6	Dual Specificity Phosphatase 6	Protein Coding	1
308	DUSP7	Dual Specificity Phosphatase 7	Protein Coding	1
309	DUSP8	Dual Specificity Phosphatase 8	Protein Coding	1
310	DUSP9	Dual Specificity Phosphatase 9	Protein Coding	1
311	EEF1G	Eukaryotic Translation Elongation Factor 1 Gamma	Protein Coding	1
312	SPRED2	Sprouty Related EVH1 Domain Containing 2	Protein Coding	1
313	EP300	EP300 Lysine Acetyltransferase	Protein Coding	1
314	ETV6	ETS Variant Transcription Factor 6	Protein Coding	1
315	FGA	Fibrinogen Alpha Chain	Protein Coding	1
316	FGB	Fibrinogen Beta Chain	Protein Coding	1
317	FGG	Fibrinogen Gamma Chain	Protein Coding	1
318	FKBP1A	FKBP Prolyl Isomerase 1A	Protein Coding	1
319	MRAS	Muscle RAS Oncogene Homolog	Protein Coding	1
320	CNKSR2	Connector Enhancer Of Kinase Suppressor Of Ras 2	Protein Coding	1
321	SEC31A	SEC31 Homolog A, COPII Component	Protein Coding	1
322	TRAK1	Trafficking Kinesin Protein 1	Protein Coding	1
323	NCBP2	Nuclear Cap Binding Protein Subunit 2	Protein Coding	1
324	SNW1	SNW Domain Containing 1	Protein Coding	1
325	DKK1	Dickkopf Wnt Signaling Pathway Inhibitor 1	Protein Coding	1
326	FOXM1	Forkhead Box M1	Protein Coding	1
327	MPRIP	Myosin Phosphatase Rho Interacting Protein	Protein Coding	1
328	KANK1	KN Motif And Ankyrin Repeat Domains 1	Protein Coding	1
329	FN1	Fibronectin 1	Protein Coding	1
330	NCSTN	Nicastrin	Protein Coding	1
331	HEY1	Hes Related Family BHLH Transcription Factor With YRPW Motif 1	Protein Coding	1
332	HEY2	Hes Related Family BHLH Transcription Factor With YRPW Motif 2	Protein Coding	1
333	ALK	ALK Receptor Tyrosine Kinase	Protein Coding	1
334	FGFR1OP2	FGFR1 Oncogene Partner 2	Protein Coding	1
335	KAT2A	Lysine Acetyltransferase 2A	Protein Coding	1
336	HEYL	Hes Related Family BHLH Transcription Factor With YRPW Motif Like	Protein Coding	1
337	SND1	Staphylococcal Nuclease And Tudor Domain Containing 1	Protein Coding	1
338	DKK4	Dickkopf Wnt Signaling Pathway Inhibitor 4	Protein Coding	1
339	DKK2	Dickkopf Wnt Signaling Pathway Inhibitor 2	Protein Coding	1
340	ERLEC1	Endoplasmic Reticulum Lectin 1	Protein Coding	1
341	EML4	EMAP Like 4	Protein Coding	1
342	GOLGA4	Golgin A4	Protein Coding	1
343	GOLGB1	Golgin B1	Protein Coding	1
344	KSR2	Kinase Suppressor Of Ras 2	Protein Coding	1
345	DLL1	Delta Like Canonical Notch Ligand 1	Protein Coding	1
346	GTF2F1	General Transcription Factor IIF Subunit 1	Protein Coding	1
347	GTF2F2	General Transcription Factor IIF Subunit 2	Protein Coding	1
348	HIP1	Huntingtin Interacting Protein 1	Protein Coding	1
349	APC	APC Regulator Of Wnt Signaling Pathway	Protein Coding	1
350	HRAS	HRas Proto-Oncogene, GTPase	Protein Coding	1
351	HES1	Hes Family BHLH Transcription Factor 1	Protein Coding	1
352	HSP90AA1	Heat Shock Protein 90 Alpha Family Class A Member 1	Protein Coding	1
353	RBPJ	Recombination Signal Binding Protein For Immunoglobulin Kappa J Region	Protein Coding	1
354	IHH	Indian Hedgehog Signaling Molecule	Protein Coding	1
355	IL10	Interleukin 10	Protein Coding	1
356	IL10RA	Interleukin 10 Receptor Subunit Alpha	Protein Coding	1
357	IRF4	Interferon Regulatory Factor 4	Protein Coding	1
358	ITGA2B	Integrin Subunit Alpha 2b	Protein Coding	1
359	ARAF	A-Raf Proto-Oncogene, Serine/Threonine Kinase	Protein Coding	1
360	ITGB3	Integrin Subunit Beta 3	Protein Coding	1
361	JAG2	Jagged Canonical Notch Ligand 2	Protein Coding	1
362	JAK2	Janus Kinase 2	Protein Coding	1
363	JUNB	JunB Proto-Oncogene, AP-1 Transcription Factor Subunit	Protein Coding	1
364	KDR	Kinase Insert Domain Receptor	Protein Coding	1
365	KIF5B	Kinesin Family Member 5B	Protein Coding	1
366	KLC1	Kinesin Light Chain 1	Protein Coding	1
367	KRAS	KRAS Proto-Oncogene, GTPase	Protein Coding	1
368	HES5	Hes Family BHLH Transcription Factor 5	Protein Coding	1
369	SPRED3	Sprouty Related EVH1 Domain Containing 3	Protein Coding	1
370	MYO18A	Myosin XVIIIA	Protein Coding	1
371	LMNA	Lamin A/C	Protein Coding	1
372	LMO7	LIM Domain 7	Protein Coding	1
373	LRP6	LDL Receptor Related Protein 6	Protein Coding	1
374	LRP5	LDL Receptor Related Protein 5	Protein Coding	1
375	LYN	LYN Proto-Oncogene, Src Family Tyrosine Kinase	Protein Coding	1
376	ARRB1	Arrestin Beta 1	Protein Coding	1
377	SMAD2	SMAD Family Member 2	Protein Coding	1
378	SMAD3	SMAD Family Member 3	Protein Coding	1
379	SMAD4	SMAD Family Member 4	Protein Coding	1
380	ARRB2	Arrestin Beta 2	Protein Coding	1
381	MARK3	Microtubule Affinity Regulating Kinase 3	Protein Coding	1
382	MCL1	MCL1 Apoptosis Regulator, BCL2 Family Member	Protein Coding	1
383	MECP2	Methyl-CpG Binding Protein 2	Protein Coding	1
384	MAP3K11	Mitogen-Activated Protein Kinase Kinase Kinase 11	Protein Coding	1
385	MSN	Moesin	Protein Coding	1
386	MYC	MYC Proto-Oncogene, BHLH Transcription Factor	Protein Coding	1
387	MYH9	Myosin Heavy Chain 9	Protein Coding	1
388	NCBP1	Nuclear Cap Binding Protein Subunit 1	Protein Coding	1
389	ATIC	5-Aminoimidazole-4-Carboxamide Ribonucleotide Formyltransferase/IMP Cyclohydrolase	Protein Coding	1
390	NF1	Neurofibromin 1	Protein Coding	1
391	NOTCH1	Notch Receptor 1	Protein Coding	1
392	NPM1	Nucleophosmin 1	Protein Coding	1
393	NRAS	NRAS Proto-Oncogene, GTPase	Protein Coding	1
394	PEBP1	Phosphatidylethanolamine Binding Protein 1	Protein Coding	1
395	NOX4	NADPH Oxidase 4	Protein Coding	1
396	IL22	Interleukin 22	Protein Coding	1
397	DHH	Desert Hedgehog Signaling Molecule	Protein Coding	1
398	DERL2	Derlin 2	Protein Coding	1
399	APH1A	Aph-1A Gamma-Secretase Subunit	Protein Coding	1
400	BIN2	Bridging Integrator 2	Protein Coding	1
401	ZC3HC1	Zinc Finger C3HC-Type Containing 1	Protein Coding	1
402	PHB1	Prohibitin 1	Protein Coding	1
403	PIM1	Pim-1 Proto-Oncogene, Serine/Threonine Kinase	Protein Coding	1
404	BCL11A	BCL11 Transcription Factor A	Protein Coding	1
405	POLR2A	RNA Polymerase II Subunit A	Protein Coding	1
406	POLR2B	RNA Polymerase II Subunit B	Protein Coding	1
407	POLR2C	RNA Polymerase II Subunit C	Protein Coding	1
408	POLR2D	RNA Polymerase II Subunit D	Protein Coding	1
409	POLR2E	RNA Polymerase II, I And III Subunit E	Protein Coding	1
410	POLR2F	RNA Polymerase II, I And III Subunit F	Protein Coding	1
411	POLR2G	RNA Polymerase II Subunit G	Protein Coding	1
412	POLR2H	RNA Polymerase II, I And III Subunit H	Protein Coding	1
413	POLR2I	RNA Polymerase II Subunit I	Protein Coding	1
414	POLR2J	RNA Polymerase II Subunit J	Protein Coding	1
415	POLR2K	RNA Polymerase II, I And III Subunit K	Protein Coding	1
416	POLR2L	RNA Polymerase II, I And III Subunit L	Protein Coding	1
417	NEURL1B	Neuralized E3 Ubiquitin Protein Ligase 1B	Protein Coding	1
418	APBB1IP	Amyloid Beta Precursor Protein Binding Family B Member 1 Interacting Protein	Protein Coding	1
419	DLL4	Delta Like Canonical Notch Ligand 4	Protein Coding	1
420	ESRP1	Epithelial Splicing Regulatory Protein 1	Protein Coding	1
421	RNF43	Ring Finger Protein 43	Protein Coding	1
422	PPM1B	Protein Phosphatase, Mg2+/Mn2+ Dependent 1B	Protein Coding	1
423	PPP1CB	Protein Phosphatase 1 Catalytic Subunit Beta	Protein Coding	1
424	PPP1CC	Protein Phosphatase 1 Catalytic Subunit Gamma	Protein Coding	1
425	AGGF1	Angiogenic Factor With G-Patch And FHA Domains 1	Protein Coding	1
426	FBXW7	F-Box And WD Repeat Domain Containing 7	Protein Coding	1
427	PRF1	Perforin 1	Protein Coding	1
428	MAML3	Mastermind Like Transcriptional Coactivator 3	Protein Coding	1
429	HHAT	Hedgehog Acyltransferase	Protein Coding	1
430	AGK	Acylglycerol Kinase	Protein Coding	1
431	PSENEN	Presenilin Enhancer, Gamma-Secretase Subunit	Protein Coding	1
432	HDAC8	Histone Deacetylase 8	Protein Coding	1
433	ERBIN	Erbb2 Interacting Protein	Protein Coding	1
434	MAPK8	Mitogen-Activated Protein Kinase 8	Protein Coding	1
435	MAPK9	Mitogen-Activated Protein Kinase 9	Protein Coding	1
436	MAP2K1	Mitogen-Activated Protein Kinase Kinase 1	Protein Coding	1
437	MAP2K2	Mitogen-Activated Protein Kinase Kinase 2	Protein Coding	1
438	PSEN1	Presenilin 1	Protein Coding	1
439	PSEN2	Presenilin 2	Protein Coding	1
440	ZC3HAV1	Zinc Finger CCCH-Type Containing, Antiviral 1	Protein Coding	1
441	AGTRAP	Angiotensin II Receptor Associated Protein	Protein Coding	1
442	BIRC6	Baculoviral IAP Repeat Containing 6	Protein Coding	1
443	MIB1	MIB E3 Ubiquitin Protein Ligase 1	Protein Coding	1
444	WDR48	WD Repeat Domain 48	Protein Coding	1
445	KIAA1549	KIAA1549	Protein Coding	1
446	RNF213	Ring Finger Protein 213	Protein Coding	1
447	PTPN6	Protein Tyrosine Phosphatase Non-Receptor Type 6	Protein Coding	1
448	PTPN12	Protein Tyrosine Phosphatase Non-Receptor Type 12	Protein Coding	1
449	RAF1	Raf-1 Proto-Oncogene, Serine/Threonine Kinase	Protein Coding	1
450	RANBP2	RAN Binding Protein 2	Protein Coding	1
451	RAP1A	RAP1A, Member Of RAS Oncogene Family	Protein Coding	1
452	RAP1B	RAP1B, Member Of RAS Oncogene Family	Protein Coding	1
453	RB1	RB Transcriptional Corepressor 1	Protein Coding	1
454	BCL2A1	BCL2 Related Protein A1	Protein Coding	1
455	BCL2L1	BCL2 Like 1	Protein Coding	1
456	ACTB	Actin Beta	Protein Coding	1
457	BCR	BCR Activator Of RhoGEF And GTPase	Protein Coding	1
458	RPS6	Ribosomal Protein S6	Protein Coding	1
459	RRBP1	Ribosome Binding Protein 1	Protein Coding	1
460	CLIP1	CAP-Gly Domain Containing Linker Protein 1	Protein Coding	1
461	SEL1L	SEL1L Adaptor Subunit Of SYVN1 Ubiquitin Ligase	Protein Coding	1
462	SHC1	SHC Adaptor Protein 1	Protein Coding	1
463	SHH	Sonic Hedgehog Signaling Molecule	Protein Coding	1
464	PORCN	Porcupine O-Acyltransferase	Protein Coding	1
465	SKP1	S-Phase Kinase Associated Protein 1	Protein Coding	1
466	SOS1	SOS Ras/Rac Guanine Nucleotide Exchange Factor 1	Protein Coding	1
467	SPTBN1	Spectrin Beta, Non-Erythrocytic 1	Protein Coding	1
468	BRAF	B-Raf Proto-Oncogene, Serine/Threonine Kinase	Protein Coding	1
469	STAT1	Signal Transducer And Activator Of Transcription 1	Protein Coding	1
470	STAT3	Signal Transducer And Activator Of Transcription 3	Protein Coding	1
471	STAT5A	Signal Transducer And Activator Of Transcription 5A	Protein Coding	1
472	STAT5B	Signal Transducer And Activator Of Transcription 5B	Protein Coding	1
473	ADAM17	ADAM Metallopeptidase Domain 17	Protein Coding	1
474	TBL1X	Transducin Beta Like 1 X-Linked	Protein Coding	1
475	TCF7L2	Transcription Factor 7 Like 2	Protein Coding	1
476	TGFB1	Transforming Growth Factor Beta 1	Protein Coding	1
477	TGFBR1	Transforming Growth Factor Beta Receptor 1	Protein Coding	1
478	TGFBR2	Transforming Growth Factor Beta Receptor 2	Protein Coding	1
479	TLN1	Talin 1	Protein Coding	1
480	ACTG1	Actin Gamma 1	Protein Coding	1
481	TPM3	Tropomyosin 3	Protein Coding	1
482	TPM4	Tropomyosin 4	Protein Coding	1
483	TPR	Translocated Promoter Region, Nuclear Basket Protein	Protein Coding	1
484	TWIST1	Twist Family BHLH Transcription Factor 1	Protein Coding	1
485	TYK2	Tyrosine Kinase 2	Protein Coding	1
486	VCL	Vinculin	Protein Coding	1
487	VCP	Valosin Containing Protein	Protein Coding	1
488	VWF	Von Willebrand Factor	Protein Coding	1
489	YES1	YES Proto-Oncogene 1, Src Family Tyrosine Kinase	Protein Coding	1
490	YWHAB	Tyrosine 3-Monooxygenase/Tryptophan 5-Monooxygenase Activation Protein Beta	Protein Coding	1
491	ZAP70	Zeta Chain Of T Cell Receptor Associated Protein Kinase 70	Protein Coding	1
492	ZMYM2	Zinc Finger MYM-Type Containing 2	Protein Coding	1
493	FZD5	Frizzled Class Receptor 5	Protein Coding	1
494	KREMEN2	Kringle Containing Transmembrane Protein 2	Protein Coding	1
495	TBL1XR1	TBL1X/Y Related 1	Protein Coding	1
496	HDAC11	Histone Deacetylase 11	Protein Coding	1
497	WDCP	WD Repeat And Coiled Coil Containing	Protein Coding	1
498	SHOC2	SHOC2 Leucine Rich Repeat Scaffold Protein	Protein Coding	1
499	DUSP16	Dual Specificity Phosphatase 16	Protein Coding	1
500	KDM7A	Lysine Demethylase 7A	Protein Coding	1
501	FXR1	FMR1 Autosomal Homolog 1	Protein Coding	1
502	FIP1L1	Factor Interacting With PAPOLA And CPSF1	Protein Coding	1
503	AXIN1	Axin 1	Protein Coding	1
504	BRAP	BRCA1 Associated Protein	Protein Coding	1
505	FZD4	Frizzled Class Receptor 4	Protein Coding	1
506	FZD6	Frizzled Class Receptor 6	Protein Coding	1
507	FZD8	Frizzled Class Receptor 8	Protein Coding	1
508	CARS1	Cysteinyl-TRNA Synthetase 1	Protein Coding	1
509	APH1B	Aph-1B Gamma-Secretase Subunit	Protein Coding	1
510	HDAC10	Histone Deacetylase 10	Protein Coding	1
511	KREMEN1	Kringle Containing Transmembrane Protein 1	Protein Coding	1
512	MAML2	Mastermind Like Transcriptional Coactivator 2	Protein Coding	1
513	SYVN1	Synoviolin 1	Protein Coding	1
514	CUL1	Cullin 1	Protein Coding	1
515	PPFIBP1	PPFIB Scaffold Protein 1	Protein Coding	1
516	AP3B1	Adaptor Related Protein Complex 3 Subunit Beta 1	Protein Coding	1
517	CBL	Cbl Proto-Oncogene	Protein Coding	1
518	TRIM24	Tripartite Motif Containing 24	Protein Coding	1
519	IQGAP1	IQ Motif Containing GTPase Activating Protein 1	Protein Coding	1
520	KSR1	Kinase Suppressor Of Ras 1	Protein Coding	1
521	KAT2B	Lysine Acetyltransferase 2B	Protein Coding	1
522	SQSTM1	Sequestosome 1	Protein Coding	1
523	CCNB1	Cyclin B1	Protein Coding	1
524	CCNC	Cyclin C	Protein Coding	1
525	WNT3A	Wnt Family Member 3A	Protein Coding	1
526	PAPSS1	3''-Phosphoadenosine 5''-Phosphosulfate Synthase 1	Protein Coding	1
527	NEURL1	Neuralized E3 Ubiquitin Protein Ligase 1	Protein Coding	1
528	LRRFIP1	LRR Binding FLII Interacting Protein 1	Protein Coding	1
529	TRIP11	Thyroid Hormone Receptor Interactor 11	Protein Coding	1
530	ZFYVE9	Zinc Finger FYVE-Type Containing 9	Protein Coding	1
531	QKI	QKI, KH Domain Containing RNA Binding	Protein Coding	1
532	EIF2AK3	Eukaryotic Translation Initiation Factor 2 Alpha Kinase 3	Protein Coding	1
533	NCOR1	Nuclear Receptor Corepressor 1	Protein Coding	1
534	NCOR2	Nuclear Receptor Corepressor 2	Protein Coding	1
535	GCC2	GRIP And Coiled-Coil Domain Containing 2	Protein Coding	1
536	FAM131B	Family With Sequence Similarity 131 Member B	Protein Coding	1
537	HDAC9	Histone Deacetylase 9	Protein Coding	1
538	HDAC4	Histone Deacetylase 4	Protein Coding	1
539	MAML1	Mastermind Like Transcriptional Coactivator 1	Protein Coding	1
540	RBX1	Ring-Box 1	Protein Coding	1
541	CAMKK2	Calcium/Calmodulin Dependent Protein Kinase Kinase 2	Protein Coding	1
542	ADCY1	Adenylate Cyclase 1	Protein Coding	1
543	AHCYL1	Adenosylhomocysteinase Like 1	Protein Coding	1
544	ADCY2	Adenylate Cyclase 2	Protein Coding	1
545	ADCY3	Adenylate Cyclase 3	Protein Coding	1
546	ADCY5	Adenylate Cyclase 5	Protein Coding	1
547	ADCY6	Adenylate Cyclase 6	Protein Coding	1
548	ADCY7	Adenylate Cyclase 7	Protein Coding	1
549	ADCY8	Adenylate Cyclase 8	Protein Coding	1
550	ADCY9	Adenylate Cyclase 9	Protein Coding	1
551	GRK2	G Protein-Coupled Receptor Kinase 2	Protein Coding	1
552	ADCY4	Adenylate Cyclase 4	Protein Coding	1
553	NBEA	Neurobeachin	Protein Coding	1
554	ITPR1	Inositol 1,4,5-Trisphosphate Receptor Type 1	Protein Coding	1
555	ITPR2	Inositol 1,4,5-Trisphosphate Receptor Type 2	Protein Coding	1
556	ITPR3	Inositol 1,4,5-Trisphosphate Receptor Type 3	Protein Coding	1
557	KPNA2	Karyopherin Subunit Alpha 2	Protein Coding	1
558	PDE1A	Phosphodiesterase 1A	Protein Coding	1
559	PDE1C	Phosphodiesterase 1C	Protein Coding	1
560	PDE1B	Phosphodiesterase 1B	Protein Coding	1
561	PRKACA	Protein Kinase CAMP-Activated Catalytic Subunit Alpha	Protein Coding	1
562	PRKACB	Protein Kinase CAMP-Activated Catalytic Subunit Beta	Protein Coding	1
563	PRKACG	Protein Kinase CAMP-Activated Catalytic Subunit Gamma	Protein Coding	1
564	PRKAR1B	Protein Kinase CAMP-Dependent Type I Regulatory Subunit Beta	Protein Coding	1
565	PRKAR2A	Protein Kinase CAMP-Dependent Type II Regulatory Subunit Alpha	Protein Coding	1
566	PRKAR2B	Protein Kinase CAMP-Dependent Type II Regulatory Subunit Beta	Protein Coding	1
567	PRKCA	Protein Kinase C Alpha	Protein Coding	1
568	PRKCD	Protein Kinase C Delta	Protein Coding	1
569	PRKCE	Protein Kinase C Epsilon	Protein Coding	1
570	PRKCG	Protein Kinase C Gamma	Protein Coding	1
571	PRKX	Protein Kinase CAMP-Dependent X-Linked Catalytic Subunit	Protein Coding	1
572	CAMK4	Calcium/Calmodulin Dependent Protein Kinase IV	Protein Coding	1
573	CAMKK1	Calcium/Calmodulin Dependent Protein Kinase Kinase 1	Protein Coding	1

Disorders associated with PIP3 activates AKT signaling SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Rasopathy	Enrichment	BRAF, CBL, HRAS, KRAS, MAP2K1, MAP2K2, MRAS, NF1, NRAS, PPP1CB, PTPN11, RAF1, SHOC2, SOS1	11.06
2	Bladder cancer	Enrichment	CDKN1A, CTNNB1, EGFR, ERBB2, ERBB3, FGFR3, HRAS, KRAS, NF1, PIK3CA, PTEN, RB1, TP53	10.86
3	Noonan syndrome and noonan-related syndrome	Enrichment	BRAF, CBL, HRAS, KRAS, MAP2K1, MAP2K2, NRAS, PTPN11, RAF1, SHOC2, SOS1, SPRED1	10.64
4	Noonan syndrome 1	Enrichment	BRAF, CBL, HRAS, KRAS, MAP2K1, MAP2K2, MRAS, NRAS, PPP1CB, PTPN11, RAF1, SHOC2, SOS1, SPRED2	10.48
5	Lung non-small cell carcinoma	Enrichment	BRAF, EGFR, ERBB2, HRAS, KRAS, MAP2K1, NRAS, PIK3CA	9.63
6	Colorectal cancer	Enrichment	AKT1, AMER1, APC, BRAF, CTNNB1, EP300, ERBB2, FBXW7, FGFR2, FGFR3, MET, NRAS, PIK3CA, PIK3R1, PTPN12, SMAD4, SRC, TP53	9.36
7	Inflammatory myofibroblastic tumor	Enrichment	ALK, CARS1, CLTC, RANBP2, TPM3, TPM4	8.87
8	Hemimegalencephaly	Enrichment	AKT3, MTOR, PIK3CA, PTEN, RHEB	8.59
9	Noonan syndrome 3	Enrichment	CLTC, HRAS, KRAS, PTPN11, RAF1, SOS1	8.04
10	Gallbladder cancer	Enrichment	BRAF, CTNNB1, KRAS, PIK3CA, SMAD4, TP53	8.04
11	Pilomyxoid astrocytoma	Enrichment	BRAF, FGFR1, KIAA1549, KRAS, NTRK2, RAF1	8.04
12	Differentiated thyroid carcinoma	Enrichment	ALK, BRAF, ETV6, HRAS, KRAS, NRAS, NTRK3, TFG, TPR, TRIM24	7.76
13	Lip and oral cavity carcinoma	Enrichment	BRAF, EGFR, HRAS, KIT, PIK3CA, RB1, TP53	7.52
14	Ovarian cancer	Enrichment	AKT1, ALK, APC, CDKN1B, CTNNB1, EGFR, ERBB2, KIT, KRAS, MET, PDGFRA, PIK3CA, PTEN, RB1, TP53, TRIM24, TSC2	7.46
15	Primary hypereosinophilic syndrome	Enrichment	ETV6, FGFR1, FIP1L1, PDGFRA, PDGFRB	7.40
16	Diffuse large b-cell lymphoma	Enrichment	BRAF, CREBBP, ETV6, FOXO1, PTEN, STAT3, TBL1XR1, TP53	7.11
17	Adult hepatocellular carcinoma	Enrichment	AXIN1, CTNNB1, EGF, PIK3CA, TP53, TSC2	6.99
18	Lung cancer susceptibility 3	Enrichment	BRAF, EGFR, ERBB2, FGF10, KRAS, RB1, TP53	6.91
19	Lung squamous cell carcinoma	Enrichment	ALK, EGFR, FGFR3, KRAS, PIK3CA	6.63
20	Nevus, epidermal	Enrichment	FGFR3, HRAS, KRAS, NRAS, PIK3CA	6.10
21	Cardiofaciocutaneous syndrome 1	Enrichment	BRAF, KRAS, MAP2K1, MAP2K2	5.91
22	Cardiofaciocutaneous syndrome	Enrichment	BRAF, KRAS, MAP2K1, MAP2K2	5.91
23	Acute promyelocytic leukemia	Enrichment	FIP1L1, NPM1, PRKAR1A, STAT3, STAT5B, TBL1XR1	5.73
24	Melanocytic nevus syndrome, congenital	Enrichment	ALK, BRAF, HRAS, NRAS, RAF1	5.68
25	Lacrimoauriculodentodigital syndrome 1	Enrichment	FGF10, FGFR2, FGFR3	5.15
26	Lung cancer	Enrichment	ALK, BRAF, EGFR, ERBB2, KRAS, MET, PIK3CA, PPP2R1B	5.13
27	Rhabdomyosarcoma	Enrichment	ALK, CBL, HRAS, NF1, PTEN, TP53	5.10
28	Gliosarcoma	Enrichment	EGFR, FGFR1, FGFR3, PPARG, TP53	5.02
29	Gastric cancer	Enrichment	APC, ERBB2, FGFR2, KRAS, NF1, PIK3CA, PTEN, SMAD4, TP53	5.02
30	Giant cell glioblastoma	Enrichment	EGFR, FGFR1, FGFR3, PPARG, TP53	4.88
31	Myeloma, multiple	Enrichment	BRAF, CREBBP, FGFR3, FLT3, HDAC4, KRAS, NCOR2, NF1, PIK3R2, TP53	4.86
32	Breast adenocarcinoma	Enrichment	AKT1, KRAS, PIK3CA, TP53	4.76
33	Thrombocytopenia	Enrichment	ETV6, FGG, ITGA2B, ITGB3, MYH9, PTPN11, SMAD4, SRC, VWF	4.61
34	Juvenile myelomonocytic leukemia	Enrichment	CBL, KRAS, NF1, NRAS, PTPN11	4.58
35	Megalencephaly-capillary malformation-polymicrogyria syndrome	Enrichment	AKT3, PIK3CA, PIK3R2	4.55
36	Focal cortical dysplasia, type ii	Enrichment	MTOR, RHEB, TSC2	4.55
37	Isolated focal cortical dysplasia type ii	Enrichment	MTOR, RHEB, TSC2	4.55
38	Glioma	Enrichment	FGFR2, NTRK3, PTEN	4.55
39	Inherited cancer-predisposing syndrome	Enrichment	ALK, APC, CDKN1B, EGFR, KIT, MET, NF1, PDGFRA, PRKAR1A, PTEN, PTPN11, RB1, SMAD4, TP53, TSC2	4.48
40	Breast cancer	Enrichment	AKT1, APC, ESR1, JUN, KLC1, KRAS, PHB1, PIK3CA, PTEN, SHC1, TP53	4.45
41	Langerhans cell histiocytosis	Enrichment	BRAF, MAP2K1, NRAS	4.43
42	Dysfibrinogenemia, congenital	Enrichment	FGA, FGB, FGG	4.43
43	Loeys-dietz syndrome 1	Enrichment	SMAD2, TGFBR1, TGFBR2	4.43
44	Familial dysfibrinogenemia	Enrichment	FGA, FGB, FGG	4.43
45	Familial hypofibrinogenemia	Enrichment	FGA, FGB, FGG	4.43
46	Thyroid cancer, nonmedullary, 2	Enrichment	BRAF, HRAS, NRAS, PTEN	4.41
47	Follicular thyroid carcinoma	Enrichment	BRAF, HRAS, NRAS, PTEN	4.41
48	Leukemia, acute myeloid	Enrichment	ETV6, FLT3, JAK2, KIT, KRAS, NPM1, NRAS, TP53	4.37
49	Meningioma	Enrichment	AKT1, PDGFB, PIK3CA, PTEN	4.22
50	Hepatocellular carcinoma	Enrichment	APC, AXIN1, CTNNB1, MET, PIK3CA, TP53	4.20
51	Loeys-dietz syndrome	Enrichment	SMAD2, SMAD3, TGFBR1, TGFBR2	3.87
52	Cowden syndrome 1	Enrichment	EGFR, PIK3CA, PTEN	3.86
53	Testicular germ cell tumor	Enrichment	FGFR3, KIT, KITLG	3.86
54	Schimmelpenning-feuerstein-mims syndrome	Enrichment	HRAS, KRAS, NRAS	3.84
55	Afibrinogenemia, congenital	Enrichment	FGA, FGB, FGG	3.84
56	Saethre-chotzen syndrome	Enrichment	FGFR2, FGFR3, TWIST1	3.84
57	Craniopharyngioma	Enrichment	APC, BRAF, CTNNB1	3.84
58	Noonan syndrome with multiple lentigines	Enrichment	BRAF, PTPN11, RAF1	3.84
59	Middle aortic syndrome	Enrichment	JAG1, NF1, RNF213	3.84
60	Squamous cell carcinoma, head and neck	Enrichment	EGFR, PTEN, TP53	3.63
61	Exudative vitreoretinopathy 1	Enrichment	CTNNB1, FZD4, LRP5	3.46
62	Rhabdomyosarcoma 2	Enrichment	FOXO1, NF1, TP53	3.46
63	Acute myeloid leukemia with maturation	Enrichment	FLT3, KIT, NPM1	3.46
64	Cervical cancer	Enrichment	FGFR3, TP53	3.43
65	Piebald trait	Enrichment	KIT, SNAI2	3.43
66	Keratosis, seborrheic	Enrichment	FGFR3, PIK3CA	3.43
67	Pfeiffer syndrome	Enrichment	FGFR1, FGFR2	3.43
68	Jackson-weiss syndrome	Enrichment	FGFR1, FGFR2	3.43
69	Rosette-forming glioneuronal tumor	Enrichment	FGFR1, PIK3CA	3.43
70	Cervix carcinoma	Enrichment	FGFR3, TP53	3.43
71	Transient predisposition to invasive pyogenic bacterial infection	Enrichment	IRAK4, MYD88	3.43
72	Long qt syndrome 1	Enrichment	CALM1, CALM2, CALM3, ITPR3, PTPN11	3.31
73	Hepatoblastoma	Enrichment	APC, CTNNB1, FGFR3, JAG1, TP53	3.28
74	Cowden syndrome	Enrichment	AKT1, PIK3CA, PTEN	3.26
75	Familial thoracic aortic aneurysm and aortic dissection	Enrichment	HEY2, NOTCH1, SMAD2, SMAD3, SMAD4, TGFBR1, TGFBR2	3.24
76	Hereditary breast carcinoma	Enrichment	AKT1, APC, ESR1, KRAS, PIK3CA, PTEN, TP53	3.24
77	Catecholaminergic polymorphic ventricular tachycardia	Enrichment	CALM1, CALM2, CALM3	3.24
78	Adrenocortical carcinoma	Enrichment	CTNNB1, PRKAR1A, TP53	3.17
79	Il10-related early-onset inflammatory bowel disease	Enrichment	IL10, IL10RA, TGFB1	3.17
80	Kallmann syndrome	Enrichment	DUSP6, FGF17, FGF8, FGFR1, POLR2F	3.09
81	Crouzon syndrome	Enrichment	FGFR2, FGFR3	2.96
82	Tumoral calcinosis, hyperphosphatemic, familial, 1	Enrichment	FGF23, KL	2.96
83	Weaver syndrome	Enrichment	EZH2, SUZ12	2.96
84	Congenital lipomatous overgrowth, vascular malformations, and epidermal nevi	Enrichment	PIK3CA, PIK3R1	2.96
85	Immunodeficiency 14a with lymphoproliferation, autosomal dominant	Enrichment	PIK3CD, PIK3R1	2.96
86	Hamartoma	Enrichment	FGFR3, TSC2	2.96
87	Testicular germ cell cancer	Enrichment	FGFR3, KIT	2.96
88	Immunodeficiency 14	Enrichment	PIK3CD, PIK3R1	2.96
89	Osteopathia striata with cranial sclerosis	Enrichment	AMER1, CTNNB1	2.96
90	Pulmonic stenosis	Enrichment	BRAF, SOS1	2.96
91	Loeys-dietz syndrome 2	Enrichment	TGFBR1, TGFBR2	2.96
92	Encephalocraniocutaneous lipomatosis	Enrichment	FGFR1, KRAS	2.96
93	Ras-associated autoimmune leukoproliferative disorder	Enrichment	KRAS, NRAS	2.96
94	Childhood hepatocellular carcinoma	Enrichment	CTNNB1, MET	2.96
95	Noonan syndrome-like disorder with loose anagen hair	Enrichment	PPP1CB, SHOC2	2.96
96	Congenital mesoblastic nephroma	Enrichment	ETV6, NTRK3	2.96
97	Fibrosarcoma	Enrichment	ETV6, NTRK3	2.96
98	Baraitser-winter cerebrofrontofacial syndrome	Enrichment	ACTB, ACTG1	2.96
99	Acute myeloid leukemia without maturation	Enrichment	FLT3, NPM1	2.96
100	Lymphomatoid papulosis	Enrichment	NPM1, TYK2	2.96
101	Chronic eosinophilic leukemia	Enrichment	FIP1L1, PDGFRA	2.96
102	Pleomorphic rhabdomyosarcoma	Enrichment	NF1, TP53	2.96
103	Primary cutaneous anaplastic large cell lymphoma	Enrichment	NPM1, TYK2	2.96
104	Spastic paraplegia-paget disease of bone syndrome	Enrichment	SQSTM1, VCP	2.96
105	Capillary malformation-arteriovenous malformation 1	Enrichment	KRAS, MAP2K1, PIK3CA	2.93
106	Leukemia, chronic myeloid	Enrichment	BCR, KRAS, NRAS	2.93
107	Adams-oliver syndrome	Enrichment	DLL4, NOTCH1, RBPJ	2.93
108	B-lymphoblastic leukemia/lymphoma with t(9;22)(q34.1;q11.2)	Enrichment	BCR, FLT3, TP53	2.93
109	Type 2 diabetes mellitus	Enrichment	AKT2, INSR, IRS1, IRS2, PPARG	2.91
110	Microform holoprosencephaly	Enrichment	DLL1, FGF8, FGFR1, SHH	2.79
111	Lobar holoprosencephaly	Enrichment	DLL1, FGF8, FGFR1, SHH	2.79
112	Lymphoma, non-hodgkin, familial	Enrichment	BRAF, PRF1, TP53	2.74
113	Exudative vitreoretinopathy	Enrichment	CTNNB1, FZD4, LRP5	2.74
114	Megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome 1	Enrichment	AKT3, PIK3R2	2.66
115	Acute myeloid leukemia with abnormal bone marrow eosinophils inv(16)(p13q22) or t(16;16)(p13;q22)	Enrichment	FLT3, KIT	2.66
116	Hirschsprung disease 1	Enrichment	ERBB2, ERBB3, IHH, NRG3, POLR2F	2.61
117	Semilobar holoprosencephaly	Enrichment	DLL1, FGF8, FGFR1, SHH	2.59
118	Normosmic congenital hypogonadotropic hypogonadism	Enrichment	DUSP6, FGF17, FGF8, FGFR1	2.59
119	Arteriovenous malformation	Enrichment	HRAS, MAP2K1, PIK3CA	2.58
120	Behavioral variant of frontotemporal dementia	Enrichment	PSEN1, SQSTM1, VCP	2.58
121	Microcephaly	Enrichment	ACTB, ACTG1, CAMK2B, CTNNB1, EP300, HDAC8, MAPK1, MECP2, PPFIBP1, PSMC3, PTPN11	2.57
122	Autism spectrum disorder	Enrichment	CSNK2A1, CSNK2B, EED, NBEA, PTEN, PTPN11, TNRC6B, TSC2	2.51
123	Desmoid disease, hereditary	Enrichment	APC, CTNNB1	2.49
124	Hyper-ige syndrome 1, autosomal dominant, with recurrent infections	Enrichment	ITGB3, STAT3	2.49
125	Bleeding disorder, platelet-type, 16	Enrichment	ITGA2B, ITGB3	2.49
126	Glomerulopathy with fibronectin deposits 2	Enrichment	ATIC, FN1	2.49
127	Osteogenic sarcoma	Enrichment	RB1, TP53	2.49
128	Osteoporosis, juvenile	Enrichment	DKK1, WNT3A	2.49
129	Alzheimer disease 4	Enrichment	PSEN1, PSEN2	2.49
130	Chromosome 8p11 myeloproliferative syndrome	Enrichment	BCR, FGFR1	2.49
131	Tethered spinal cord syndrome	Enrichment	BRAF, CREBBP	2.49
132	Large congenital melanocytic nevus	Enrichment	HRAS, NRAS	2.49
133	Breast implant-associated anaplastic large cell lymphoma	Enrichment	JAK2, STAT3	2.49
134	Desmoid tumor	Enrichment	APC, CTNNB1	2.49
135	Squamous cell carcinoma	Enrichment	RB1, TP53	2.49
136	Bone osteosarcoma	Enrichment	RB1, TP53	2.49
137	Spermatocytoma	Enrichment	FGFR3, HRAS	2.49
138	Neonatal inflammatory skin and bowel disease	Enrichment	ADAM17, EGFR	2.49
139	Keratoacanthoma	Enrichment	NOTCH1, PIK3CA	2.49
140	Hemifacial hyperplasia	Enrichment	FGFR2, FGFR3	2.45
141	Lymphoma	Enrichment	PTPN11, TP53	2.45
142	Holoprosencephaly	Enrichment	FGF8, FGFR1	2.45
143	Acute megakaryocytic leukemia	Enrichment	PTEN, TP53	2.45
144	Acute myeloid leukemia with t(8;21)(q22;q22) translocation	Enrichment	FLT3, KIT	2.45
145	Myopathy, x-linked, with excessive autophagy	Enrichment	HRAS, MAP2K1, PIK3CA	2.43
146	Autosomal dominant macrothrombocytopenia	Enrichment	ITGA2B, ITGB3, TPM4	2.43
147	Connective tissue disease	Enrichment	FGFR3, NOTCH1, SMAD3, TGFBR2, TRIP11	2.41
148	Pectus excavatum	Enrichment	PTPN11, SHOC2, TGFBR1	2.30
149	Autosomal dominant non-syndromic intellectual disability	Enrichment	CAMK2A, CAMK2B, CSNK2B, ERBB4, NBEA	2.29
150	Li-fraumeni syndrome	Enrichment	MDM2, TP53	2.28
151	Holoprosencephaly 1	Enrichment	FGF8, FGFR1	2.28
152	Patent ductus arteriosus	Enrichment	PSMC3, PTPN11	2.28
153	46,xy disorder of sex development	Enrichment	FGFR3, INSR	2.28
154	Tooth agenesis	Enrichment	FGFR1, LRP6, RANBP2, TGFA	2.26
155	Small cell cancer of the lung	Enrichment	RB1, TP53	2.20
156	Thyroid cancer, nonmedullary, 1	Enrichment	BRAF, TP53	2.20
157	Neurofibromatosis-noonan syndrome	Enrichment	MAP2K2, NF1	2.20
158	Chromosome 22q11.2 deletion syndrome, distal	Enrichment	BCR, MAPK1	2.20
159	Lung sarcomatoid carcinoma	Enrichment	KRAS, TP53	2.20
160	Chronic myelogenous leukemia, bcr-abl1 positive	Enrichment	KRAS, NRAS	2.20
161	Chronic myelomonocytic leukemia	Enrichment	ETV6, FLT3	2.20
162	Retinopathy of prematurity	Enrichment	FZD4, LRP5	2.20
163	Cerebrovascular disease	Enrichment	PIK3CA, RNF213	2.20
164	Embryonal rhabdomyosarcoma	Enrichment	NF1, TP53	2.20
165	Aortic aneurysm	Enrichment	SMAD3, TGFBR1	2.20
166	Noonan syndrome-like disorder with or without juvenile myelomonocytic leukemia	Enrichment	CBL, PTPN11	2.20
167	Pilocytic astrocytoma	Enrichment	KRAS, NF1	2.20
168	Sick sinus syndrome	Enrichment	LMNA, MECP2	2.20
169	Non-syndromic bicoronal craniosynostosis	Enrichment	FGFR3, TWIST1	2.20
170	Spinocerebellar ataxia, autosomal recessive 16	Enrichment	ITPR1, STUB1	2.15
171	Multiple endocrine neoplasia, type i	Enrichment	CDKN1A, CDKN1B	2.14
172	Gastrointestinal stromal tumor	Enrichment	KIT, PDGFRA	2.14
173	Waardenburg syndrome, type 2e	Enrichment	KITLG, SNAI2	2.14
174	Renal cell carcinoma, papillary, 1	Enrichment	MET, MTOR	2.14
175	Overgrowth syndrome	Enrichment	MTOR, PIK3R1	2.14
176	Endometrial cancer	Enrichment	FGFR2, PIK3CA, PTEN	2.14
177	Congenital nervous system abnormality	Enrichment	CAMK2B, CREBBP, CTNNB1, ERLIN2, FGFR3, MECP2, PSEN1, PTEN, TSC2	2.05
178	Nervous system disease	Enrichment	CAMK2B, CREBBP, CTNNB1, ERLIN2, FGFR3, MECP2, PSEN1, PTEN, TSC2	2.05
179	Glioma susceptibility 1	Enrichment	ERBB2, TP53	2.02
180	Basal ganglia calcification, idiopathic, 1	Enrichment	PDGFB, PDGFRB	2.02
181	Tetralogy of fallot	Enrichment	HEY2, JAG1, KDR, NOTCH1	1.99
182	Complex neurodevelopmental disorder	Enrichment	AGO1, AGO2, CSNK2A1, PPP2CA, PSMD12, RNF2, TNRC6B	1.99
183	Pervasive developmental disorder	Enrichment	FBXW7, SPTBN1	1.98
184	Myeloproliferative neoplasm	Enrichment	CBL, JAK2	1.98
185	Hemangioma	Enrichment	PTEN, RNF213	1.98
186	Coloboma of choroid and retina	Enrichment	ACTG1, FZD5	1.98
187	Rare pervasive developmental disorder	Enrichment	FBXW7, SPTBN1	1.98
188	Neurodevelopmental disorder with dysmorphic facies and distal limb anomalies	Enrichment	RAC1, TNRC6B	1.91
189	Lynch syndrome	Enrichment	KRAS, PIK3CA, TGFBR2	1.91
190	Rare genetic intellectual disability	Enrichment	CREBBP, EP300, MTOR	1.91
191	Septopreoptic holoprosencephaly	Enrichment	DLL1, FGF8, SHH	1.91
192	Midline interhemispheric variant of holoprosencephaly	Enrichment	DLL1, FGF8, SHH	1.91
193	Polymicrogyria	Enrichment	AKT3, PSMC3	1.82
194	Autosomal non-syndromic agammaglobulinemia	Enrichment	PIK3CD, PIK3R1	1.82
195	Klippel-trenaunay-weber syndrome	Enrichment	AGGF1, PIK3CA	1.82
196	Rubinstein-taybi syndrome 1	Enrichment	CREBBP, EP300	1.82
197	Hemangioma, capillary infantile	Enrichment	KDR, MYH9	1.82
198	Chromosome 16p13.3 deletion syndrome, proximal	Enrichment	CREBBP, EP300	1.82
199	Fetomaternal alloimmune thrombocytopenia 1	Enrichment	ITGA2B, ITGB3	1.82
200	Ellis-van creveld syndrome	Enrichment	PRKACA, PRKACB	1.79
201	Dandy-walker syndrome	Enrichment	BRAF, PDGFRB, PPP1CB	1.75
202	Polycystic liver disease	Enrichment	CTNNB1, LRP5, LRP6	1.75
203	Autosomal dominant polycystic liver disease	Enrichment	CTNNB1, LRP5, LRP6	1.75
204	Alobar holoprosencephaly	Enrichment	DLL1, FGF8, SHH	1.75
205	Prostate cancer	Enrichment	PIK3CA, PTEN, TP53	1.75
206	Meningioma, familial	Enrichment	PDGFB, PTEN	1.74
207	Specific learning disability	Enrichment	MAPK1, PTPN11	1.74
208	Long qt syndrome	Enrichment	AKAP9, CALM1, CALM2, LMNA	1.73
209	Non-immune hydrops fetalis	Enrichment	FZD6, HRAS, KRAS, PTPN11	1.73
210	Erythroleukemia, familial	Enrichment	ERBB3	1.71
211	Hypochondroplasia	Enrichment	FGFR3	1.71
212	Macrodactyly	Enrichment	PIK3CA	1.71
213	Proteus syndrome	Enrichment	AKT1	1.71
214	Beare-stevenson cutis gyrata syndrome	Enrichment	FGFR2	1.71
215	Paget disease, extramammary	Enrichment	ERBB2	1.71
216	Osteoglophonic dysplasia	Enrichment	FGFR1	1.71
217	Metachondromatosis	Enrichment	PTPN11	1.71
218	Thanatophoric dysplasia, type i	Enrichment	FGFR3	1.71
219	Trigonocephaly 1	Enrichment	FGFR1	1.71
220	Hypoinsulinemic hypoglycemia with hemihypertrophy	Enrichment	AKT2	1.71
221	Donohue syndrome	Enrichment	INSR	1.71
222	Muenke syndrome	Enrichment	FGFR3	1.71
223	Vacterl association with hydrocephalus	Enrichment	PTEN	1.71
224	Premature aging syndrome, penttinen type	Enrichment	PDGFRB	1.71
225	Spermatogenic failure, x-linked, 9	Enrichment	RBBP7	1.71
226	Hyperinsulinemic hypoglycemia, familial, 5	Enrichment	INSR	1.71
227	Immunodeficiency due to defect in mapbp-interacting protein	Enrichment	LAMTOR2	1.71
228	Deafness, autosomal recessive 26	Enrichment	GAB1	1.71
229	Pineal hyperplasia, insulin-resistant diabetes mellitus, and somatic abnormalities	Enrichment	INSR	1.71
230	Hypomagnesemia 4, renal	Enrichment	EGF	1.71
231	46,xy sex reversal 5	Enrichment	CBX2	1.71
232	Immunodeficiency 68	Enrichment	MYD88	1.71
233	Diabetes mellitus, insulin-resistant, with acanthosis nigricans	Enrichment	INSR	1.71
234	Hypereosinophilic syndrome, idiopathic	Enrichment	PDGFRA	1.71
235	Immunodeficiency 73a with defective neutrophil chemotaxis and leukocytosis	Enrichment	RAC2	1.71
236	Deafness, autosomal recessive 39	Enrichment	HGF	1.71
237	Mastocytosis, cutaneous	Enrichment	KIT	1.71
238	Scaphocephaly, maxillary retrusion, and impaired intellectual development	Enrichment	FGFR2	1.71
239	Macroglobulinemia, waldenstrom 1	Enrichment	MYD88	1.71
240	Megalencephaly, autosomal dominant	Enrichment	PIK3CA	1.71
241	Apert syndrome	Enrichment	FGFR2	1.71
242	Basal ganglia calcification, idiopathic, 5	Enrichment	PDGFB	1.71
243	Hyperpigmentation with or without hypopigmentation, familial progressive	Enrichment	KITLG	1.71
244	Leopard syndrome 1	Enrichment	PTPN11	1.71
245	Ivic syndrome	Enrichment	SALL4	1.71
246	Cowden syndrome 5	Enrichment	PIK3CA	1.71
247	Myofibromatosis, infantile, 1	Enrichment	PDGFRB	1.71
248	Thanatophoric dysplasia, type ii	Enrichment	FGFR3	1.71
249	Lethal congenital contracture syndrome 2	Enrichment	ERBB3	1.71
250	Gand syndrome	Enrichment	GATAD2B	1.71
251	Hypogonadotropic hypogonadism 20 with or without anosmia	Enrichment	FGF17	1.71
252	Fetal encasement syndrome	Enrichment	CHUK	1.71
253	Microcephaly 11, primary, autosomal recessive	Enrichment	PHC1	1.71
254	Gist-plus syndrome	Enrichment	PDGFRA	1.71
255	Camptodactyly, tall stature, and hearing loss syndrome	Enrichment	FGFR3	1.71
256	Ataxia-oculomotor apraxia 3	Enrichment	PIK3R5	1.71
257	Accelerated tumor formation	Enrichment	MDM2	1.71
258	Aplasia of lacrimal and salivary glands	Enrichment	FGF10	1.71
259	Bent bone dysplasia syndrome 1	Enrichment	FGFR2	1.71
260	Wilms tumor 6	Enrichment	REST	1.71
261	Global developmental delay with speech and behavioral abnormalities	Enrichment	TNRC6B	1.71
262	Congenital hypotonia, epilepsy, developmental delay, and digital anomalies	Enrichment	ATN1	1.71
263	Luo-schoch-yamamoto syndrome	Enrichment	RNF2	1.71
264	Cerebral cavernous malformations 4	Enrichment	PIK3CA	1.71
265	Visceral neuropathy, familial, 2, autosomal recessive	Enrichment	ERBB2	1.71
266	Noonan syndrome 13	Enrichment	MAPK1	1.71
267	Neurodevelopmental disorder with microcephaly, hypotonia, and absent language	Enrichment	PSMB1	1.71
268	Developmental and epileptic encephalopathy 58	Enrichment	NTRK2	1.71
269	Tumoral calcinosis, hyperphosphatemic, familial, 3	Enrichment	KL	1.71
270	Lessel-kubisch syndrome	Enrichment	MDM2	1.71
271	Short syndrome	Enrichment	PIK3R1	1.71
272	Bone marrow failure syndrome 5	Enrichment	TP53	1.71
273	Houge-janssens syndrome 4	Enrichment	PPP2R5C	1.71
274	Stankiewicz-isidor syndrome	Enrichment	PSMD12	1.71
275	Osteofibrous dysplasia	Enrichment	MET	1.71
276	Papilloma of choroid plexus	Enrichment	TP53	1.71
277	Basal cell carcinoma 7	Enrichment	TP53	1.71
278	Imagawa-matsumoto syndrome	Enrichment	SUZ12	1.71
279	Myeloid and lymphoid neoplasms associated with pdgfra rearrangement	Enrichment	PDGFRA	1.71
280	Immunodeficiency 73c with defective neutrophil chemotaxis and hypogammaglobulinemia	Enrichment	RAC2	1.71
281	Anaplastic thyroid carcinoma	Enrichment	TP53	1.71
282	Metacarpal 4-5 fusion	Enrichment	FGF16	1.71
283	Papillary tumor of the pineal region	Enrichment	PTEN	1.71
284	Lacrimoauriculodentodigital syndrome 3	Enrichment	FGF10	1.71
285	Familial isolated trichomegaly	Enrichment	FGF5	1.71
286	Houge-janssens syndrome 2	Enrichment	PPP2R1A	1.71
287	Deafness, cataract, impaired intellectual development, and polyneuropathy	Enrichment	PSMC3	1.71
288	Deafness, autosomal recessive 97	Enrichment	MET	1.71
289	Radioulnar synostosis with amegakaryocytic thrombocytopenia 2	Enrichment	MECOM	1.71
290	Megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome 2	Enrichment	AKT3	1.71
291	Skin/hair/eye pigmentation, variation in, 7	Enrichment	KITLG	1.71
292	Crouzon syndrome with acanthosis nigricans	Enrichment	FGFR3	1.71
293	Hemifacial myohyperplasia	Enrichment	PIK3CA	1.71
294	Capillary malformation of the lower lip, lymphatic malformation of face and neck, asymmetry of face and limbs, and partial/generalized overgrowth	Enrichment	PIK3CA	1.71
295	Ovarian dysgenesis 8	Enrichment	ESR2	1.71
296	Neuroendocrine tumor	Enrichment	CDKN1B	1.71
297	Autism 9	Enrichment	MET	1.71
298	Immunodeficiency 67	Enrichment	IRAK4	1.71
299	Deafness, autosomal dominant 27	Enrichment	REST	1.71
300	Multiple synostoses syndrome 3	Enrichment	FGF9	1.71
301	Glaucoma 1, open angle, o	Enrichment	NTF4	1.71
302	Basal ganglia calcification, idiopathic, 4	Enrichment	PDGFRB	1.71
303	Immunodeficiency 36 with lymphoproliferation	Enrichment	PIK3R1	1.71
304	Cowden syndrome 6	Enrichment	AKT1	1.71
305	Cleft palate, psychomotor retardation, and distinctive facial features	Enrichment	KDM1A	1.71
306	Amyotrophic lateral sclerosis 19	Enrichment	ERBB4	1.71
307	Immunodeficiency 14b, autosomal recessive	Enrichment	PIK3CD	1.71
308	Myeloid and lymphoid neoplasms associated with pdgfrb rearrangement	Enrichment	PDGFRB	1.71
309	Immunodeficiency, common variable, 3	Enrichment	CD19	1.71
310	Agammaglobulinemia 7, autosomal recessive	Enrichment	PIK3R1	1.71
311	Acute myeloid leukemia with minimal differentiation	Enrichment	FLT3	1.71
312	Immunodeficiency 97 with autoinflammation	Enrichment	PIK3CG	1.71
313	Immunodeficiency 123 with hpv-related verrucosis	Enrichment	CD28	1.71
314	Hypogonadotropic hypogonadism 6 with or without anosmia	Enrichment	FGF8	1.71
315	Obesity, hyperphagia, and developmental delay	Enrichment	NTRK2	1.71
316	Glioma susceptibility 2	Enrichment	PTEN	1.71
317	Achondroplasia, severe, with developmental delay and acanthosis nigricans	Enrichment	FGFR3	1.71
318	Ductal carcinoma in situ	Enrichment	TP53	1.71
319	Kosaki overgrowth syndrome	Enrichment	PDGFRB	1.71
320	Fibromatosis, gingival, 5	Enrichment	REST	1.71
321	Tumoral calcinosis, hyperphosphatemic, familial, 2	Enrichment	FGF23	1.71
322	Hartsfield syndrome	Enrichment	FGFR1	1.71
323	Epilepsy, familial adult myoclonic, 6	Enrichment	TNRC6A	1.71
324	Renal hypodysplasia/aplasia 2	Enrichment	FGF20	1.71
325	Immunodeficiency 22	Enrichment	LCK	1.71
326	Thrombocytopenia 6	Enrichment	SRC	1.71
327	Cohen-gibson syndrome	Enrichment	EED	1.71
328	Okur-chung neurodevelopmental syndrome	Enrichment	CSNK2A1	1.71
329	Bartsocas-papas syndrome 2	Enrichment	CHUK	1.71
330	Ocular pterygium-digital keloid dysplasia syndrome	Enrichment	PDGFRB	1.71
331	Immunodeficiency 73b with defective neutrophil chemotaxis and lymphopenia	Enrichment	RAC2	1.71
332	Chronic mast cell leukemia	Enrichment	KIT	1.71
333	Segmental progressive overgrowth syndrome with fibroadipose hyperplasia	Enrichment	PIK3CA	1.71
334	Severe intellectual disability-poor language-strabismus-grimacing face-long fingers syndrome	Enrichment	GATAD2B	1.71
335	Thyroid gland undifferentiated carcinoma	Enrichment	TP53	1.71
336	Deafness, autosomal dominant 69	Enrichment	KITLG	1.71
337	Small-cell carcinoma of the ovary of hypercalcemic type	Enrichment	TP53	1.71
338	Arthrogryposis, distal, type 11	Enrichment	MET	1.71
339	Lacrimoauriculodentodigital syndrome 2	Enrichment	FGFR3	1.71
340	Pparg-associated congenital generalized lipodystrophy	Enrichment	PPARG	1.71
341	Immunodeficiency 125	Enrichment	FLT3LG	1.71
342	Palatal anomalies-widely spaced teeth-facial dysmorphism-developmental delay syndrome	Enrichment	KDM1A	1.71
343	Short-rib thoracic dysplasia 22 without polydactyly	Enrichment	FGF4	1.71
344	Hypospadias	Enrichment	PIK3CA	1.71
345	Craniodigital syndrome and intellectual disability syndrome	Enrichment	CSNK2B	1.71
346	Capillary hemangioma	Enrichment	AKT3	1.71
347	Diffuse pediatric-type high-grade glioma, h3-wildtype and idh-wildtype	Enrichment	TP53	1.71
348	Isolated bone marrow mastocytosis	Enrichment	KIT	1.71
349	Acth-independent macronodular adrenal hyperplasia 3	Enrichment	KDM1A	1.71
350	Smoldering systemic mastocytosis	Enrichment	KIT	1.71
351	Choroid plexus cancer	Enrichment	TP53	1.71
352	Rare venous malformation	Enrichment	PIK3CA	1.71
353	Diaphragmatic eventration	Enrichment	PIK3CA	1.71
354	Infantile lad-like disease due to rac2 deficiency	Enrichment	RAC2	1.71
355	Fgfr3-related chondrodysplasia	Enrichment	FGFR3	1.71
356	Waldenstram macroglobulinemia	Enrichment	MYD88	1.71
357	Reticular dysgenesis-like severe combined immunodeficiency	Enrichment	RAC2	1.71
358	Mastocytosis	Enrichment	KIT	1.71
359	Pik3ca-related overgrowth spectrum	Enrichment	PIK3CA	1.71
360	Combined immunodeficiency-hypogammaglobulinemia-skeletal anomalies syndrome due to ikbka deficiency	Enrichment	CHUK	1.71
361	Camptodactyly-tall stature-scoliosis-hearing loss syndrome	Enrichment	FGFR3	1.71
362	Familial progressive hyperpigmentation	Enrichment	KITLG	1.71
363	Pleomorphic xanthoastrocytoma	Enrichment	TP53	1.71
364	Rare combined vascular malformation	Enrichment	PIK3CA	1.71
365	Cavernous lymphangioma	Enrichment	PIK3CA	1.71
366	Pik3ca-related overgrowth syndrome	Enrichment	PIK3CA	1.71
367	Cutaneous mastocytoma	Enrichment	KIT	1.71
368	Sall4-related disorders	Enrichment	SALL4	1.71
369	Typical urticaria pigmentosa	Enrichment	KIT	1.71
370	Primary immunodeficiency syndrome due to p14 deficiency	Enrichment	LAMTOR2	1.71
371	Ppp2r1a-related neurodevelopmental disorder	Enrichment	PPP2R1A	1.71
372	Segmental outgrowth-lipomatosis-arteriovenous malformation-epidermal nevus syndrome	Enrichment	PTEN	1.71
373	Microcephaly-corpus callosum and cerebellar vermis hypoplasia-facial dysmorphism-intellectual disability syndrom	Enrichment	RAC1	1.71
374	Nodular urticaria pigmentosa	Enrichment	KIT	1.71
375	Hartsfield-bixler-demyer syndrome	Enrichment	FGFR1	1.71
376	Hemihyperplasia-multiple lipomatosis syndrome	Enrichment	PIK3CA	1.71
377	Pseudoxanthomatous diffuse cutaneous mastocytosis	Enrichment	KIT	1.71
378	Telangiectasia macularis eruptiva perstans	Enrichment	KIT	1.71
379	Acute mast cell leukemia	Enrichment	KIT	1.71
380	Eccrine angiomatous hamartoma	Enrichment	PIK3CA	1.71
381	Rac2-related combined immunodeficiency-bronchiectasis-cancer-predisposing syndrome	Enrichment	RAC2	1.71
382	Egf-related primary hypomagnesemia with intellectual disability	Enrichment	EGF	1.71
383	Non-syndromic unicoronal craniosynostosis	Enrichment	FGFR2	1.71
384	Familial progressive hyper- and hypopigmentation	Enrichment	KITLG	1.71
385	Tubular renal disease-cardiomyopathy syndrome	Enrichment	RRAGD	1.71
386	Plaque-form urticaria pigmentosa	Enrichment	KIT	1.71
387	Interstitial lung disease specific to childhood	Enrichment	FGF10	1.71
388	Macrodactyly of toe	Enrichment	PIK3CA	1.71
389	Serous carcinoma of the corpus uteri	Enrichment	ERBB2	1.71
390	Bullous diffuse cutaneous mastocytosis	Enrichment	KIT	1.71
391	Akt2-related familial partial lipodystrophy	Enrichment	AKT2	1.71
392	Malignant astrocytoma	Enrichment	PTPN11	1.71
393	Testis seminoma	Enrichment	KIT	1.71
394	Heart, malformation of	Enrichment	CDK8, JAG1, MAPK1	1.68
395	Esophageal cancer	Enrichment	TGFBR2, TP53	1.68
396	Myelofibrosis	Enrichment	JAK2, SRC	1.68
397	Glanzmann thrombasthenia 1	Enrichment	ITGA2B, ITGB3	1.68
398	Essential thrombocythemia	Enrichment	JAK2, TP53	1.68
399	Early-onset autosomal dominant alzheimer disease	Enrichment	PSEN1, PSEN2	1.68
400	Anhidrosis, isolated, with normal sweat glands	Enrichment	ITPR2	1.65
401	Acrodysostosis 1 with or without hormone resistance	Enrichment	PRKAR1A	1.65
402	Carney complex, type 1	Enrichment	PRKAR1A	1.65
403	Dyskinesia with orofacial involvement, autosomal dominant	Enrichment	ADCY5	1.65
404	Deafness, autosomal recessive 44	Enrichment	ADCY1	1.65
405	Autoimmune lymphoproliferative syndrome, type iii	Enrichment	PRKCD	1.65
406	Neurodevelopmental disorder with hyperkinetic movements and dyskinesia	Enrichment	ADCY5	1.65
407	Charcot-marie-tooth disease, demyelinating, type 1j	Enrichment	ITPR3	1.65
408	Intellectual developmental disorder, autosomal recessive 63	Enrichment	CAMK2A	1.65
409	Intellectual developmental disorder, autosomal dominant 54	Enrichment	CAMK2B	1.65
410	Immune dysregulation, autoimmunity, and autoinflammation	Enrichment	PLCG1	1.65
411	Cardioacrofacial dysplasia 2	Enrichment	PRKACB	1.65
412	Myxoma, intracardiac	Enrichment	PRKAR1A	1.65
413	Neurodevelopmental disorder with or without early-onset generalized epilepsy	Enrichment	NBEA	1.65
414	Dyskinesia with orofacial involvement, autosomal recessive	Enrichment	ADCY5	1.65
415	Spinocerebellar ataxia 14	Enrichment	PRKCG	1.65
416	Long qt syndrome 16	Enrichment	CALM3	1.65
417	Pigmented nodular adrenocortical disease, primary, 4	Enrichment	PRKACA	1.65
418	Cardioacrofacial dysplasia 1	Enrichment	PRKACA	1.65
419	Deafness, autosomal dominant 74	Enrichment	PDE1C	1.65
420	Intellectual developmental disorder, autosomal dominant 53	Enrichment	CAMK2A	1.65
421	Intellectual developmental disorder, autosomal dominant 59	Enrichment	CAMK2G	1.65
422	Long qt syndrome 15	Enrichment	CALM2	1.65
423	Immunodeficiency 133 with ectodermal dysplasia with or without peripheral neuropathy	Enrichment	ITPR3	1.65
424	Prkar1b-related neurodegenerative dementia with intermediate filaments	Enrichment	PRKAR1B	1.65
425	Arteriovenous malformations of the brain	Enrichment	BRAF, EGFR, KRAS	1.62
426	Neuropathy, hereditary motor and sensory, okinawa type	Enrichment	LMNA, TFG, VCP	1.62
427	Nk-cell enteropathy	Enrichment	ERBB4, PIK3CB	1.60
428	Left ventricular noncompaction	Enrichment	LMNA, MIB1, MIB2, RAF1	1.55
429	Congenital long qt syndrome	Enrichment	ITPR3, PTPN11	1.55
430	Familial isolated dilated cardiomyopathy	Enrichment	LMNA, PSEN1, PSEN2, RAF1, VCL	1.51
431	Renal cell carcinoma, nonpapillary	Enrichment	MET, MTOR	1.48
432	Hydrocephalus	Enrichment	FGFR2, PDGFRB	1.48
433	Holoprosencephaly 3	Enrichment	SHH	1.48
434	Chiari malformation type i	Enrichment	DKK1	1.48
435	Perry syndrome	Enrichment	DCTN1	1.48
436	Endosteal hyperostosis, autosomal dominant	Enrichment	LRP5	1.48
437	Fetal hemoglobin quantitative trait locus 5	Enrichment	BCL11A	1.48
438	Nail disorder, nonsyndromic congenital, 1	Enrichment	FZD6	1.48
439	Paget disease of bone 3	Enrichment	SQSTM1	1.48
440	46,xy sex reversal 7	Enrichment	DHH	1.48
441	Achondrogenesis, type ia	Enrichment	TRIP11	1.48
442	Von willebrand disease, type 1	Enrichment	VWF	1.48
443	Chondrodysplasia with platyspondyly, distinctive brachydactyly, hydrocephaly, and microphthalmia	Enrichment	HDAC6	1.48
444	Baraitser-winter syndrome 1	Enrichment	ACTB	1.48
445	Oculoectodermal syndrome	Enrichment	KRAS	1.48
446	Pallister-killian syndrome	Enrichment	ARAF	1.48
447	Bone mineral density quantitative trait locus 1	Enrichment	LRP5	1.48
448	Exudative vitreoretinopathy 4	Enrichment	LRP5	1.48
449	Hypothyroidism, congenital, nongoitrous, 8	Enrichment	TBL1X	1.48
450	Hemophagocytic lymphohistiocytosis, familial, 2	Enrichment	PRF1	1.48
451	Immunodeficiency 50	Enrichment	MSN	1.48
452	Focal dermal hypoplasia	Enrichment	PORCN	1.48
453	Aica-ribosiduria due to atic deficiency	Enrichment	ATIC	1.48
454	Legius syndrome	Enrichment	SPRED1	1.48
455	Immunodeficiency 35	Enrichment	TYK2	1.48
456	Noonan syndrome 5	Enrichment	RAF1	1.48
457	Noonan syndrome 4	Enrichment	SOS1	1.48
458	Deafness, autosomal dominant 17	Enrichment	MYH9	1.48
459	Facial hypertrichosis	Enrichment	MECP2	1.48
460	Spastic paraplegia 18b, autosomal recessive	Enrichment	ERLIN2	1.48
461	Skin/hair/eye pigmentation, variation in, 8	Enrichment	IRF4	1.48
462	Melorheostosis, isolated	Enrichment	MAP2K1	1.48
463	Inclusion body myopathy with early-onset paget disease with or without frontotemporal dementia 1	Enrichment	VCP	1.48
464	Noonan syndrome 7	Enrichment	BRAF	1.48
465	Leopard syndrome 3	Enrichment	BRAF	1.48
466	Neuroblastoma 3	Enrichment	ALK	1.48
467	Acne inversa, familial, 1	Enrichment	NCSTN	1.48
468	Microphthalmia/coloboma 5	Enrichment	SHH	1.48
469	Cardiomyopathy, dilated, 1nn	Enrichment	RAF1	1.48
470	Congenital myopathy 4b, autosomal recessive	Enrichment	TPM3	1.48
471	Multiple self-healing squamous epithelioma	Enrichment	TGFBR1	1.48
472	Von willebrand disease, type 2	Enrichment	VWF	1.48
473	Cardiofaciocutaneous syndrome 3	Enrichment	MAP2K1	1.48
474	Melanosis, neurocutaneous	Enrichment	NRAS	1.48
475	Tooth agenesis, selective, 7	Enrichment	LRP6	1.48
476	Spastic paraplegia 57, autosomal recessive	Enrichment	TFG	1.48
477	Sessile serrated polyposis cancer syndrome	Enrichment	RNF43	1.48
478	Caudal duplication anomaly	Enrichment	AXIN1	1.48
479	Noonan syndrome 6	Enrichment	NRAS	1.48
480	Odontochondrodysplasia 1	Enrichment	TRIP11	1.48
481	Ectodermal dysplasia 13, hair/tooth type	Enrichment	KREMEN1	1.48
482	Noonan syndrome 11	Enrichment	MRAS	1.48
483	Exudative vitreoretinopathy 8	Enrichment	LRP6	1.48
484	Halperin-birk syndrome	Enrichment	SEC31A	1.48
485	Charcot-marie-tooth disease, axonal, type 2hh	Enrichment	JAG1	1.48
486	Myopathy, distal, with rimmed vacuoles	Enrichment	SQSTM1	1.48
487	Growth hormone insensitivity syndrome with immune dysregulation 2, autosomal dominant	Enrichment	STAT5B	1.48
488	Neurodevelopmental disorder with seizures, microcephaly, and brain abnormalities	Enrichment	PPFIBP1	1.48
489	Intellectual developmental disorder, x-linked, syndromic, lubs type	Enrichment	MECP2	1.48
490	Frontotemporal dementia and/or amyotrophic lateral sclerosis 3	Enrichment	SQSTM1	1.48
491	Adams-oliver syndrome 6	Enrichment	DLL4	1.48
492	Intellectual developmental disorder, x-linked, syndromic, houge type	Enrichment	CNKSR2	1.48
493	Bleeding disorder, platelet-type, 25	Enrichment	TPM4	1.48
494	Immunodeficiency 131	Enrichment	IRF4	1.48
495	Chromosome 2q37 deletion syndrome	Enrichment	HDAC4	1.48
496	Auriculocondylar syndrome 4	Enrichment	HDAC9	1.48
497	Autism x-linked 3	Enrichment	MECP2	1.48
498	Cornelia de lange syndrome 5	Enrichment	HDAC8	1.48
499	Immunodeficiency 48	Enrichment	ZAP70	1.48
500	Von willebrand disease, type 3	Enrichment	VWF	1.48
501	Fetomaternal alloimmune thrombocytopenia 2	Enrichment	ITGA2B	1.48
502	Nivelon-nivelon-mabille syndrome	Enrichment	HHAT	1.48
503	Congenital smooth muscle hamartoma, with or without hemihypertrophy	Enrichment	ACTB	1.48
504	Graft-versus-host disease	Enrichment	IL10	1.48
505	Cataract 38	Enrichment	AGK	1.48
506	Hypospadias 2, x-linked	Enrichment	MAMLD1	1.48
507	T-cell large granular lymphocyte leukemia	Enrichment	STAT3	1.48
508	Developmental delay, impaired speech, and behavioral abnormalities	Enrichment	SPTBN1	1.48
509	Noonan syndrome 14	Enrichment	SPRED2	1.48
510	Cardiomyopathy, dilated, 1v	Enrichment	PSEN2	1.48
511	Osteoporosis-pseudoglioma syndrome	Enrichment	LRP5	1.48
512	Coronary artery disease, autosomal dominant 2	Enrichment	LRP6	1.48
513	Cardiofaciocutaneous syndrome 2	Enrichment	KRAS	1.48
514	Alzheimer disease 18	Enrichment	ADAM10	1.48
515	Neurodevelopmental-craniofacial syndrome with variable renal and cardiac abnormalities	Enrichment	ZMYM2	1.48
516	Cardiomyopathy, dilated, 1w	Enrichment	VCL	1.48
517	Lymphangioma	Enrichment	BRAF	1.48
518	Long qt syndrome 11	Enrichment	AKAP9	1.48
519	Noonan syndrome-like disorder with loose anagen hair 1	Enrichment	SHOC2	1.48
520	Acrocapitofemoral dysplasia	Enrichment	IHH	1.48
521	Hereditary spastic paraplegia 18	Enrichment	ERLIN2	1.48
522	Polycystic liver disease 4 with or without kidney cysts	Enrichment	LRP5	1.48
523	Phace association	Enrichment	BRAF	1.48
524	Becker nevus syndrome	Enrichment	ACTB	1.48
525	Neuronopathy, distal hereditary motor, autosomal dominant 14	Enrichment	DCTN1	1.48
526	Melorheostosis	Enrichment	MAP2K1	1.48
527	Dystonia-deafness syndrome 1	Enrichment	ACTB	1.48
528	Colorectal cancer, hereditary nonpolyposis, type 6	Enrichment	TGFBR2	1.48
529	Cardiomyopathy, dilated, 1u	Enrichment	PSEN1	1.48
530	Leopard syndrome 2	Enrichment	RAF1	1.48
531	Cerebral palsy, spastic quadriplegic, 2	Enrichment	KANK1	1.48
532	Cardiomyopathy, familial hypertrophic, 15	Enrichment	VCL	1.48
533	Immunodeficiency 31a	Enrichment	STAT1	1.48
534	Cardiofaciocutaneous syndrome 4	Enrichment	MAP2K2	1.48
535	Thrombocytopenia 11 with multiple congenital anomalies and dysmorphic facies	Enrichment	RAP1B	1.48
536	Hypogonadotropic hypogonadism 19 with or without anosmia	Enrichment	DUSP6	1.48
537	Reticulate acropigmentation of kitamura	Enrichment	ADAM10	1.48
538	Syndromic x-linked intellectual disability lubs type	Enrichment	MECP2	1.48
539	Loeys-dietz syndrome 6	Enrichment	SMAD2	1.48
540	Microphthalmia/coloboma 11	Enrichment	FZD5	1.48
541	Acne inversa, familial, 2, with or without dowling-degos disease	Enrichment	PSENEN	1.48
542	Immunodeficiency 31b	Enrichment	STAT1	1.48
543	Acne inversa, familial, 3	Enrichment	PSEN1	1.48
544	Frontotemporal dementia and/or amyotrophic lateral sclerosis 6	Enrichment	VCP	1.48
545	Autoimmune disease, multisystem, infantile-onset, 2	Enrichment	ZAP70	1.48
546	Autoimmune disease, multisystem, infantile-onset, 1	Enrichment	STAT3	1.48
547	Visual impairment and progressive phthisis bulbi	Enrichment	MARK3	1.48
548	Intellectual developmental disorder with persistence of fetal hemoglobin	Enrichment	BCL11A	1.48
549	Atypical werner syndrome	Enrichment	LMNA	1.48
550	Retinitis pigmentosa 86	Enrichment	KIAA1549	1.48
551	Muscular dystrophy, limb-girdle, autosomal recessive 27	Enrichment	JAG2	1.48
552	Noonan syndrome-like disorder with loose anagen hair 2	Enrichment	PPP1CB	1.48
553	Deafness, congenital heart defects, and posterior embryotoxon	Enrichment	JAG1	1.48
554	Autoinflammatory disease, systemic, with vasculitis	Enrichment	LYN	1.48
555	Intellectual developmental disorder, autosomal recessive 79	Enrichment	TPR	1.48
556	Von willebrand's disease	Enrichment	VWF	1.48
557	Thrombocytopenia 8, with dysmorphic features and developmental delay	Enrichment	ACTB	1.48
558	Menke-hennekam syndrome 1	Enrichment	CREBBP	1.48
559	Hyperplastic polyposis syndrome	Enrichment	RNF43	1.48
560	Developmental and epileptic encephalopathy 68	Enrichment	TRAK1	1.48
561	Congenital myopathy 9b, proximal, with minicore lesions	Enrichment	FXR1	1.48
562	Neurodevelopmental disorder with central hypotonia and dysmorphic facies	Enrichment	HDAC4	1.48
563	Neurodevelopmental disorder with poor growth, absent speech, progressive ataxia, and dysmorphic facies	Enrichment	SEL1L	1.48
564	Congenital myopathy 9a	Enrichment	FXR1	1.48
565	Ceroid lipofuscinosis, neuronal, 15	Enrichment	CLCN6	1.48
566	Multisystem proteinopathy	Enrichment	VCP	1.48
567	Trigonitis	Enrichment	RAF1	1.48
568	Autosomal recessive spastic paraplegia type 60	Enrichment	WDR48	1.48
569	Tufted angioma of skin	Enrichment	KDR	1.48
570	Craniometadiaphyseal osteosclerosis with hip dysplasia	Enrichment	AXIN1	1.48
571	Trilateral retinoblastoma	Enrichment	RB1	1.48
572	Plexiform neurofibroma	Enrichment	NF1	1.48
573	Congenital heart defects, multiple types, 8, with or without heterotaxy	Enrichment	SMAD2	1.48
574	Hermansky-pudlak syndrome due to ap3b1 deficiency	Enrichment	AP3B1	1.48
575	Developmental delay, hypotonia, and impaired language	Enrichment	FBXW7	1.48
576	Adenoid ameloblastoma	Enrichment	CTNNB1	1.48
577	Neurofibroma	Enrichment	NF1	1.48
578	B-lymphoblastic leukemia/lymphoma with t(12;21)(p13.2;q22.1)	Enrichment	ETV6	1.48
579	Baraitser-winter syndrome	Enrichment	ACTB	1.48
580	Heritable thoracic aortic disease	Enrichment	SMAD4	1.48
581	Bcl11a-related intellectual disability	Enrichment	BCL11A	1.48
582	Adult-onset distal myopathy due to vcp mutation	Enrichment	VCP	1.48
583	Mandibuloacral dysplasia	Enrichment	LMNA	1.48
584	Atrioventricular block	Enrichment	LMNA	1.48
585	Rubinstein-taybi syndrome due to 16p13.3 microdeletion	Enrichment	CREBBP	1.48
586	Congenital fibrinogen deficiency	Enrichment	FGG	1.48
587	Lrp5-related primary osteoporosis	Enrichment	LRP5	1.48
588	Neurofibromatosis	Enrichment	NF1	1.48
589	Spastic paraplegia 18a, autosomal dominant	Enrichment	ERLIN2	1.48
590	Stat3-related early-onset multisystem autoimmune disease	Enrichment	STAT3	1.48
591	Chromosome 17q11.2 deletion syndrome	Enrichment	NF1	1.48
592	Acute myeloid leukemia with multilineage dysplasia	Enrichment	NPM1	1.48
593	Autosomal dominant nonsyndromic hearing loss 17	Enrichment	MYH9	1.48
594	Congenital pulmonary airway malformation	Enrichment	KRAS	1.48
595	Optic nerve glioma	Enrichment	NF1	1.48
596	Acute myeloid leukemia with npm1 somatic mutations	Enrichment	NPM1	1.48
597	Alk-positive anaplastic large cell lymphoma	Enrichment	ALK	1.48
598	Vegetative pyoderma gangrenosum	Enrichment	PTPN6	1.48
599	Familial adenomatous polyposis	Enrichment	APC	1.48
600	Bullous pyoderma gangrenosum	Enrichment	PTPN6	1.48
601	Congenital smooth muscle hamartoma	Enrichment	ACTB	1.48
602	Capillary leak syndrome	Enrichment	TLN1	1.48
603	Pustular pyoderma gangrenosum	Enrichment	PTPN6	1.48
604	Syringocystadenoma papilliferum	Enrichment	BRAF	1.48
605	Developmental malformations-deafness-dystonia syndrome	Enrichment	ACTB	1.48
606	Menke-hennekam syndrome	Enrichment	CREBBP	1.48
607	Ganglioglioma	Enrichment	BRAF	1.48
608	Whipple disease	Enrichment	IRF4	1.48
609	Nongerminomatous germ cell tumor	Enrichment	BRAF	1.48
610	Lmna-related cardiocutaneous progeria syndrome	Enrichment	LMNA	1.48
611	Familial acute necrotizing encephalopathy	Enrichment	RANBP2	1.48
612	Phace syndrome	Enrichment	BRAF	1.48
613	Gardner syndrome	Enrichment	APC	1.48
614	Osteosclerosis-developmental delay-craniosynostosis syndrome	Enrichment	LRP5	1.48
615	Recessive intellectual disability-motor dysfunction-multiple joint contractures syndrome	Enrichment	ERLIN2	1.48
616	5q22 microdeletion syndrome	Enrichment	APC	1.48
617	Phakomatosis pigmentokeratotica	Enrichment	HRAS	1.48
618	Pash syndrome	Enrichment	NCSTN	1.48
619	Attenuated familial adenomatous polyposis	Enrichment	APC	1.48
620	Huntington's disease-like	Enrichment	PSEN2	1.48
621	Classic hairy cell leukemia	Enrichment	BRAF	1.48
622	Autosomal dominant charcot-marie-tooth disease type 2 due to tfg mutation	Enrichment	TFG	1.48
623	Classic pyoderma gangrenosum	Enrichment	PTPN6	1.48
624	Autosomal semi-dominant severe lipodystrophic laminopathy	Enrichment	LMNA	1.48
625	Fatal post-viral neurodegenerative disorder	Enrichment	PRF1	1.48
626	Alk-positive large b-cell lymphoma	Enrichment	ALK	1.48
627	Chronic lymphoproliferative disorder of natural killer cells	Enrichment	STAT3	1.48
628	Autosomal dominant combined immunodeficiency due to erbin deficiency	Enrichment	ERBIN	1.48
629	Congenital generalized hypercontractile muscle stiffness syndrome	Enrichment	TPM3	1.48
630	Neurocutaneous melanocytosis	Enrichment	NRAS	1.48
631	Zap70-related severe combined immunodeficiency	Enrichment	ZAP70	1.48
632	Microcystic stromal tumor	Enrichment	CTNNB1	1.48
633	Autosomal recessive axonal hereditary motor and sensory neuropathy	Enrichment	LMNA	1.48
634	Autosomal dominant preaxial polydactyly-upperback hypertrichosis syndrome	Enrichment	SHH	1.48
635	Laminopathy	Enrichment	LMNA	1.48
636	Lung oat cell carcinoma	Enrichment	RB1	1.48
637	46,xy ovotesticular disorder of sex development	Enrichment	MAMLD1	1.48
638	Neurofibromatosis, type i	Enrichment	NF1, SPRED1	1.47
639	Leukemia, acute lymphoblastic 3	Enrichment	JAK2, NF1	1.47
640	Atypical chronic myeloid leukemia, bcr-abl1 negative	Enrichment	FLT3, MYO18A	1.47
641	Progressive non-fluent aphasia	Enrichment	PSEN1, VCP	1.47
642	Primary hyperaldosteronism	Enrichment	BRAF, TP53	1.47
643	Myocardial infarction	Enrichment	ESR1, ITGB3, PSMA6	1.45
644	Skin disease	Enrichment	CLCN6, NCSTN, NF1	1.45
645	Myeloproliferative disorder, chronic, with eosinophilia	Enrichment	PDGFRB	1.42
646	Fibromatosis, gingival, 1	Enrichment	REST	1.42
647	Dentatorubral-pallidoluysian atrophy	Enrichment	ATN1	1.42
648	Otodental dysplasia	Enrichment	FGF3	1.42
649	Adrenocortical carcinoma, hereditary	Enrichment	TP53	1.42
650	Trichomegaly	Enrichment	FGF5	1.42
651	Visceral neuropathy, familial, 1, autosomal recessive	Enrichment	ERBB3	1.42
652	Pulmonary hypoplasia, primary	Enrichment	FGF10	1.42
653	Carotid intimal medial thickness 1	Enrichment	PPARG	1.42
654	Dermatofibrosarcoma protuberans	Enrichment	PDGFB	1.42
655	Immunodeficiency 33	Enrichment	IRAK4	1.42
656	Lethal congenital contracture syndrome 3	Enrichment	PIP5K1C	1.42
657	Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy 2	Enrichment	PIK3R5	1.42
658	Histiocytoma, angiomatoid fibrous	Enrichment	CREB1	1.42
659	Premature ovarian failure 3	Enrichment	AGO2	1.42
660	Lymphangioleiomyomatosis	Enrichment	TSC2	1.42
661	Hyperinsulinemic hypoglycemia, familial, 4	Enrichment	INSR	1.42
662	Aural atresia, congenital	Enrichment	FGFR2	1.42
663	Deafness, congenital, with inner ear agenesis, microtia, and microdontia	Enrichment	FGF3	1.42
664	Duane-radial ray syndrome	Enrichment	SALL4	1.42
665	Neutrophilia, hereditary	Enrichment	PIP4K2B	1.42
666	Roifman-chitayat syndrome	Enrichment	PIK3CD	1.42
667	Sifrim-hitz-weiss syndrome	Enrichment	CHD4	1.42
668	Maturity-onset diabetes of the young, type 10	Enrichment	INS	1.42
669	Noonan syndrome 8	Enrichment	PIK3CA	1.42
670	Lymphoma, hodgkin, classic	Enrichment	TP53	1.42
671	Neutropenia, severe congenital, 7, autosomal recessive	Enrichment	PIP4K2B	1.42
672	Multiple endocrine neoplasia, type iv	Enrichment	CDKN1B	1.42
673	Houge-janssens syndrome 1	Enrichment	PPP2R5D	1.42
674	Antley-bixler syndrome without genital anomalies or disordered steroidogenesis	Enrichment	FGFR2	1.42
675	Waardenburg syndrome, type 2f	Enrichment	KITLG	1.42
676	Hyperproinsulinemia	Enrichment	INS	1.42
677	Intellectual developmental disorder, autosomal dominant 48	Enrichment	RAC1	1.42
678	Hypomagnesemia 7, renal, with or without dilated cardiomyopathy	Enrichment	RRAGD	1.42
679	Snijders blok-campeau syndrome	Enrichment	CHD3	1.42
680	Birk-aharoni syndrome	Enrichment	PSMC1	1.42
681	Neurodevelopmental disorder with language delay and behavioral abnormalities, with or without seizures	Enrichment	AGO1	1.42
682	Werner syndrome	Enrichment	PTPN11	1.42
683	Spondyloepiphyseal dysplasia, nishimura type	Enrichment	WWP2	1.42
684	Spinocerebellar ataxia 48	Enrichment	STUB1	1.42
685	Poirier-bienvenu neurodevelopmental syndrome	Enrichment	CSNK2B	1.42
686	Cebalid syndrome	Enrichment	MTOR	1.42
687	Infantile myofibromatosis	Enrichment	PDGFRB	1.42
688	Proteasome-associated autoinflammatory syndrome 3	Enrichment	PSMB4	1.42
689	Senior-loken syndrome 7	Enrichment	AKT3	1.42
690	Split hand-foot malformation	Enrichment	FGFR2	1.42
691	Papillary renal cell carcinoma	Enrichment	MET	1.42
692	Congenital fibrosarcoma	Enrichment	TP53	1.42
693	Li-fraumeni syndrome 1	Enrichment	TP53	1.42
694	Severe congenital neutropenia 7	Enrichment	PIP4K2B	1.42
695	Sarcoma	Enrichment	TP53	1.42
696	Congenital dyserythropoietic anemia	Enrichment	IRAK4	1.42
697	Diabetes mellitus, permanent neonatal, 4	Enrichment	INS	1.42
698	Intellectual developmental disorder, autosomal dominant 60, with seizures	Enrichment	PIP5K1A	1.42
699	Immune system disease	Enrichment	PIK3CD	1.42
700	Hodgkin's lymphoma	Enrichment	TP53	1.42
701	Bardet-biedl syndrome 16	Enrichment	AKT3	1.42
702	B-lymphoblastic leukemia/lymphoma with hyperdiploidy	Enrichment	PIP4K2A	1.42
703	Hao-fountain syndrome	Enrichment	USP7	1.42
704	Smith-kingsmore syndrome	Enrichment	MTOR	1.42
705	17q24.2 microdeletion syndrome	Enrichment	PSMD12	1.42
706	Houge-janssens syndrome 3	Enrichment	PPP2CA	1.42
707	Interfrontal craniofaciosynostosis	Enrichment	FGFR1	1.42
708	Radioulnar synostosis	Enrichment	MECOM	1.42
709	Long-olsen-distelmaier syndrome	Enrichment	RRAGC	1.42
710	Common variable immunodeficiency phenotype due to cd19/cd81 deficiency	Enrichment	CD19	1.42
711	Familial partial lipodystrophy	Enrichment	PPARG	1.42
712	Autosomal dominant nonsyndromic deafness	Enrichment	FGFR2	1.42
713	Vacterl with hydrocephalus	Enrichment	PTEN	1.42
714	B-lymphoblastic leukemia/lymphoma with recurrent genetic abnormality	Enrichment	PDGFRA	1.42
715	Acute myeloid leukemia with inv(3)(q21q26.2) or t(3;3)(q21;q26.2)	Enrichment	MECOM	1.42
716	Mixed phenotype acute leukemia with t(9;22)(q34.1;q11.2)	Enrichment	FLT3	1.42
717	B-lymphoblastic leukemia/lymphoma with t	Enrichment	KIT	1.42
718	Juvenile polyposis of infancy	Enrichment	PTEN	1.42
719	Oculootodental syndrome	Enrichment	FGF3	1.42
720	Submucosal cleft palate	Enrichment	UBB	1.42
721	Radio-ulnar synostosis-amegakaryocytic thrombocytopenia syndrome	Enrichment	MECOM	1.42
722	Cleft hard palate	Enrichment	UBB	1.42
723	Precursor t-cell acute lymphoblastic leukemia	Enrichment	BCR, FLT3, MYC	1.40
724	Cat eye syndrome	Enrichment	ACTG1, FZD5	1.38
725	Marfan syndrome	Enrichment	TGFBR1, TGFBR2	1.38
726	Frontotemporal dementia and/or amyotrophic lateral sclerosis 1	Enrichment	SQSTM1, VCP	1.38
727	Melanoma	Enrichment	BRAF, PTEN	1.38
728	Frontotemporal dementia and/or amyotrophic lateral sclerosis 7	Enrichment	DCTN1, ERBB4, PSEN1, SQSTM1, VCP	1.36
729	Spinocerebellar ataxia 29	Enrichment	ITPR1	1.35
730	Amelogenesis imperfecta, type ig	Enrichment	PRKAR1A	1.35
731	Pigmented nodular adrenocortical disease, primary, 1	Enrichment	PRKAR1A	1.35
732	Ventricular tachycardia, catecholaminergic polymorphic, 4	Enrichment	CALM1	1.35
733	Lethal congenital contracture syndrome 8	Enrichment	ADCY6	1.35
734	Bleeding disorder, platelet-type, 19	Enrichment	PRKACG	1.35
735	Long qt syndrome 14	Enrichment	CALM1	1.35
736	Marbach-schaaf neurodevelopmental syndrome	Enrichment	PRKAR1B	1.35
737	Cerebellar, ocular, craniofacial, and genital syndrome	Enrichment	NBEA	1.35
738	Usher syndrome, type iv	Enrichment	PRKAR1A	1.35
739	Acrodysostosis	Enrichment	PRKAR1A	1.35
740	Body mass index quantitative trait locus 19	Enrichment	ADCY3	1.35
741	Fibrolamellar carcinoma	Enrichment	PRKACA	1.35
742	Ciliary dyskinesia, primary, 18	Enrichment	PRKAR1B	1.35
743	Isolated primary pigmented nodular adrenocortical disease	Enrichment	PRKAR1A	1.35
744	Patent foramen ovale	Enrichment	PSMC3, PTPN11	1.33
745	Pancreatic cancer	Enrichment	KRAS, SMAD4, TP53	1.31
746	Frontotemporal dementia 1	Enrichment	DCTN1, PSEN1	1.30
747	Leukemia, acute lymphoblastic	Enrichment	ETV6, FLT3	1.30
748	Hydrops fetalis, nonimmune	Enrichment	FZD6, HRAS, PTPN11	1.27
749	Craniosynostosis	Enrichment	FGFR2, FGFR3	1.25
750	Achondroplasia	Enrichment	FGFR3	1.25
751	Type 1 diabetes mellitus 2	Enrichment	INS	1.25
752	Prognathism, mandibular	Enrichment	CSNK2B	1.25
753	Hypogonadotropic hypogonadism 2 with or without anosmia	Enrichment	FGFR1	1.25
754	Larsen syndrome	Enrichment	FGFR3	1.25
755	Thyroid carcinoma, familial medullary	Enrichment	ESR2	1.25
756	Hypophosphatemic rickets, autosomal dominant	Enrichment	FGF23	1.25
757	Proteasome-associated autoinflammatory syndrome 1	Enrichment	PSMB4	1.25
758	Pompe disease, infantile-onset	Enrichment	PIK3CA	1.25
759	Mycosis fungoides	Enrichment	CD28	1.25
760	Tuberous sclerosis 1	Enrichment	TSC2	1.25
761	Uvula, bifid	Enrichment	UBB	1.25
762	Polycystic kidney disease, infantile severe, with tuberous sclerosis	Enrichment	TSC2	1.25
763	Cleft soft palate	Enrichment	UBB	1.25
764	Nasopharyngeal carcinoma	Enrichment	TP53	1.25
765	Estrogen resistance	Enrichment	ESR1	1.25
766	Tuberous sclerosis 2	Enrichment	TSC2	1.25
767	Neonatal nephrocutaneous inflammatory syndrome	Enrichment	EGFR	1.25
768	Dedifferentiated liposarcoma	Enrichment	MDM2	1.25
769	Proteosome-associated autoinflammatory syndrome	Enrichment	PSMB4	1.25
770	Atypical teratoid rhabdoid tumor	Enrichment	TP53	1.25
771	Anaplastic astrocytoma	Enrichment	TP53	1.25
772	Xanthinuria, type ii	Enrichment	TSC2	1.25
773	Adenocarcinoma	Enrichment	TP53	1.25
774	Duane retraction syndrome	Enrichment	SALL4	1.25
775	Migraine without aura	Enrichment	ESR1	1.25
776	Laryngeal squamous cell carcinoma	Enrichment	PTEN	1.25
777	Lessel-kreienkamp syndrome	Enrichment	AGO2	1.25
778	Cushing syndrome due to bilateral macronodular adrenocortical disease	Enrichment	KDM1A	1.25
779	Melanoma of soft tissue	Enrichment	CREB1	1.25
780	Tricuspid valve insufficiency	Enrichment	PTPN11	1.25
781	Well-differentiated liposarcoma	Enrichment	MDM2	1.25
782	Mixed phenotype acute leukemia with t	Enrichment	FLT3	1.25
783	Renal cell carcinoma	Enrichment	MET	1.25
784	Thyroid hemiagenesis	Enrichment	PSMD3	1.25
785	Testicular cancer	Enrichment	FGFR3	1.25
786	Saczary syndrome	Enrichment	CD28	1.25
787	Septooptic dysplasia	Enrichment	FGFR1, SHH	1.23
788	Cafe-au-lait spots, multiple	Enrichment	NF1	1.18
789	Burkitt lymphoma	Enrichment	MYC	1.18
790	Myhre syndrome	Enrichment	SMAD4	1.18
791	Camurati-engelmann disease 1	Enrichment	TGFB1	1.18
792	Spondyloepimetaphyseal dysplasia, strudwick type	Enrichment	FN1	1.18
793	Costello syndrome	Enrichment	HRAS	1.18
794	Van buchem disease	Enrichment	LRP5	1.18
795	Spondylometaphyseal dysplasia, corner fracture type	Enrichment	FN1	1.18
796	Epiphyseal dysplasia, multiple, with early-onset diabetes mellitus	Enrichment	EIF2AK3	1.18
797	Robinow-sorauf syndrome	Enrichment	TWIST1	1.18
798	Mandibuloacral dysplasia with type a lipodystrophy	Enrichment	LMNA	1.18
799	Thumb deformity	Enrichment	CREBBP	1.18
800	Growth hormone insensitivity syndrome with immune dysregulation 1, autosomal recessive	Enrichment	STAT5B	1.18
801	Camptodactyly-arthropathy-coxa vara-pericarditis syndrome	Enrichment	TPR	1.18
802	Ebstein anomaly	Enrichment	CDK8	1.18
803	Encephalopathy, neonatal severe, due to mecp2 mutations	Enrichment	MECP2	1.18
804	Ovarian germ cell cancer	Enrichment	CBL	1.18
805	Cataract 35	Enrichment	MYH9	1.18
806	Alzheimer disease 3	Enrichment	PSEN1	1.18
807	46,xy gonadal dysgenesis with minifascicular neuropathy	Enrichment	DHH	1.18
808	Amyotrophic lateral sclerosis 6 with or without frontotemporal dementia	Enrichment	VCP	1.18
809	Inflammatory bowel disease 28, autosomal recessive	Enrichment	IL10RA	1.18
810	Waardenburg syndrome, type 4c	Enrichment	POLR2F	1.18
811	Pick disease of brain	Enrichment	PSEN1	1.18
812	Juvenile polyposis/hereditary hemorrhagic telangiectasia syndrome	Enrichment	SMAD4	1.18
813	Welander distal myopathy	Enrichment	SQSTM1	1.18
814	Microvascular complications of diabetes 5	Enrichment	TGFBR2	1.18
815	Heart-hand syndrome, slovenian type	Enrichment	LMNA	1.18
816	Deafness, autosomal dominant 20	Enrichment	ACTG1	1.18
817	Charcot-marie-tooth disease, axonal, type 2b1	Enrichment	LMNA	1.18
818	Melanoma, cutaneous malignant 6	Enrichment	KLC1	1.18
819	Primary lateral sclerosis, juvenile	Enrichment	ERLIN2	1.18
820	Solitary median maxillary central incisor	Enrichment	SHH	1.18
821	Baraitser-winter syndrome 2	Enrichment	ACTG1	1.18
822	Adams-oliver syndrome 5	Enrichment	NOTCH1	1.18
823	Cardiomyopathy, dilated, with hypergonadotropic hypogonadism	Enrichment	LMNA	1.18
824	Chromosome 13q14 deletion syndrome	Enrichment	RB1	1.18
825	Angioma, tufted	Enrichment	KDR	1.18
826	Fatty liver disease 1	Enrichment	ATG7	1.18
827	Thrombocythemia 3	Enrichment	JAK2	1.18
828	Syndactyly, type iii	Enrichment	HDAC8	1.18
829	Albinism, oculocutaneous, type ia	Enrichment	NOX4	1.18
830	Loeys-dietz syndrome 3	Enrichment	SMAD3	1.18
831	Adams-oliver syndrome 3	Enrichment	RBPJ	1.18
832	Immunodeficiency 31c	Enrichment	STAT1	1.18
833	Cardiomyopathy, dilated, 1d	Enrichment	LMNA	1.18
834	Neurodegeneration with ataxia, dystonia, and gaze palsy, childhood-onset	Enrichment	SQSTM1	1.18
835	Restrictive dermopathy 2	Enrichment	LMNA	1.18
836	Sweeney-cox syndrome	Enrichment	TWIST1	1.18
837	Emery-dreifuss muscular dystrophy 3, autosomal recessive	Enrichment	LMNA	1.18
838	Deafness, autosomal recessive 109	Enrichment	ESRP1	1.18
839	Hypotonia, ataxia, developmental delay, and tooth enamel defect syndrome	Enrichment	CTBP1	1.18
840	Neurodevelopmental disorder with nonspecific brain abnormalities and with or without seizures	Enrichment	DLL1	1.18
841	Neurodevelopmental disorder with developmental delay and with or without motor or speech delay	Enrichment	CUX1	1.18
842	Menke-hennekam syndrome 2	Enrichment	EP300	1.18
843	Chromosome 17q11.2 duplication syndrome, 1.4-mb	Enrichment	NF1	1.18
844	Inflammatory bowel disease, immunodeficiency, and encephalopathy	Enrichment	TGFB1	1.18
845	Intellectual developmental disorder, x-linked, syndromic 13	Enrichment	MECP2	1.18
846	Hermansky-pudlak syndrome 2	Enrichment	AP3B1	1.18
847	Wilson-turner syndrome	Enrichment	HDAC8	1.18
848	Left ventricular noncompaction 7	Enrichment	MIB1	1.18
849	Acute myeloid leukemia with kat6a-crebbp fusion	Enrichment	CREBBP	1.18
850	Cerebellar ataxia, deafness, and narcolepsy, autosomal dominant	Enrichment	DNMT1	1.18
851	X-linked intellectual disability-psychosis-macroorchidism syndrome	Enrichment	MECP2	1.18
852	Lipodystrophy, familial partial, type 1	Enrichment	LMNA	1.18
853	Hematologic cancer	Enrichment	ETV6	1.18
854	Spinocerebellar ataxia, autosomal recessive 31	Enrichment	ATG7	1.18
855	Camurati-engelmann disease	Enrichment	TGFB1	1.18
856	Inflammatory bowel disease 28	Enrichment	IL10RA	1.18
857	Neurogenic bladder	Enrichment	CLCN6	1.18
858	Respiratory system disease	Enrichment	CLCN6	1.18
859	Peripheral demyelinating neuropathy, central dysmyelination, waardenburg syndrome, and hirschsprung disease	Enrichment	POLR2F	1.18
860	Inflammatory skin and bowel disease, neonatal, 1	Enrichment	ADAM17	1.18
861	Angiocentric glioma	Enrichment	QKI	1.18
862	Bardet-biedl syndrome 9	Enrichment	NF1	1.18
863	Periampullary adenoma	Enrichment	APC	1.18
864	Gastric adenocarcinoma and proximal polyposis of the stomach	Enrichment	APC	1.18
865	Pseudosarcomatous fibromatosis	Enrichment	MYH9	1.18
866	Paget's disease of bone	Enrichment	SQSTM1	1.18
867	Polycythemia	Enrichment	JAK2	1.18
868	Juvenile nasopharyngeal angiofibroma	Enrichment	CTNNB1	1.18
869	Intellectual developmental disorder with hypotonia and behavioral abnormalities	Enrichment	CDK8	1.18
870	Distal hereditary motor neuropathy type 7	Enrichment	DCTN1	1.18
871	Hypereosinophilic syndrome	Enrichment	JAK2	1.18
872	Posterior hypospadias	Enrichment	MAMLD1	1.18
873	X-linked myotubular myopathy-abnormal genitalia syndrome	Enrichment	MAMLD1	1.18
874	Malignant germ cell tumor of ovary	Enrichment	CBL	1.18
875	Neurodevelopmental disorder with hypotonia, poor growth, dysmorphic facies, and agammaglobulinemia	Enrichment	SEL1L	1.18
876	Teratoma	Enrichment	CTNNB1	1.18
877	Osteosclerosis	Enrichment	LRP5	1.18
878	Familial retinoblastoma	Enrichment	RB1	1.18
879	Non-syndromic sagittal craniosynostosis	Enrichment	TWIST1	1.18
880	Skeletal muscle disease	Enrichment	KIF5B	1.18
881	Charcot-marie-tooth disease type 2b1	Enrichment	LMNA	1.18
882	Non-syndromic syndactyly	Enrichment	AGGF1	1.18
883	Isolated radial hemimelia	Enrichment	SHH	1.18
884	Acute necrotizing encephalopathy of childhood	Enrichment	RANBP2	1.18
885	Tafro syndrome	Enrichment	MAP2K2	1.18
886	Progressive bulbar palsy	Enrichment	MECP2	1.18
887	Laron syndrome with immunodeficiency	Enrichment	STAT5B	1.18
888	Wooly hair nevus	Enrichment	HRAS	1.18
889	Bruxism	Enrichment	MECP2	1.18
890	Gillespie syndrome	Enrichment	ITPR1	1.18
891	Hypomyelination neuropathy-arthrogryposis syndrome	Enrichment	ADCY6	1.18
892	Aortic valve disease 1	Enrichment	NOTCH1, SOS1	1.17
893	Alzheimer's disease	Enrichment	PSEN1, VCP	1.17
894	Lipodystrophy, familial partial, type 3	Enrichment	PPARG	1.12
895	Immunodeficiency, common variable, 1	Enrichment	ICOS	1.12
896	Barrett esophagus	Enrichment	ERBB2	1.12
897	Leptin deficiency or dysfunction	Enrichment	PPARG	1.12
898	Congenital generalized lipodystrophy	Enrichment	PPARG	1.12
899	Arthrogryposis multiplex congenita 3, myogenic type	Enrichment	ESR1	1.12
900	Enophthalmos	Enrichment	CSNK2B	1.12
901	Multiple synostoses syndrome	Enrichment	FGF9	1.12
902	Syndactyly	Enrichment	CSNK2B	1.12
903	Neonatal diabetes mellitus	Enrichment	INS	1.12
904	Tuberous sclerosis	Enrichment	TSC2	1.12
905	Familial cerebral cavernous malformations	Enrichment	PIK3CA	1.12
906	Pediatric systemic lupus erythematosus	Enrichment	IRAK1	1.12
907	Primary hyperparathyroidism	Enrichment	CDKN1B	1.12
908	Systemic mastocytosis with associated hematologic neoplasm	Enrichment	KIT	1.12
909	Gingival fibromatosis	Enrichment	REST	1.12
910	Osteoporosis	Enrichment	LRP5, SRC	1.11
911	Medulloblastoma	Enrichment	APC, CTNNB1	1.11
912	Aortic aneurysm, familial thoracic 1	Enrichment	NOTCH1, SMAD3	1.11
913	Chorea, benign hereditary	Enrichment	ADCY5	1.06
914	Carney complex variant	Enrichment	PRKAR1A	1.06
915	Spinocerebellar ataxia 15	Enrichment	ITPR1	1.06
916	Arrhythmogenic right ventricular dysplasia, familial, 10	Enrichment	PRKAR1A	1.06
917	Hereditary ataxia	Enrichment	PRKCG	1.06
918	Polydactyly, postaxial, type a1	Enrichment	BCL11A, EP300	1.06
919	Corpus callosum, agenesis of	Enrichment	BCL11A, CREBBP	1.06
920	Isolated corpus callosum agenesis	Enrichment	BCL11A, CREBBP	1.06
921	Intellectual disability-hypoplastic corpus callosum-preauricular tag syndrome	Enrichment	BCL11A, CREBBP	1.06
922	Autism	Enrichment	CAMK2G, CREBBP, MECP2, SHH, TCF7L2	1.04
923	Ectodermal dysplasia 10a, hypohidrotic/hair/nail type, autosomal dominant	Enrichment	TRAF6	1.03
924	Capillary malformations, congenital	Enrichment	PIK3CA	1.03
925	Severe combined immunodeficiency, autosomal recessive, t cell-negative, b cell-positive, nk cell-negative	Enrichment	SALL4	1.03
926	Macrocephaly/autism syndrome	Enrichment	PTEN	1.03
927	Endometrial stromal sarcoma	Enrichment	SUZ12	1.03
928	Male infertility with azoospermia or oligozoospermia due to single gene mutation	Enrichment	FGF8, KLB, PTPN11	1.03
929	Brachydactyly, type a1	Enrichment	IHH	1.01
930	Craniosynostosis 1	Enrichment	TWIST1	1.01
931	Macrothrombocytopenia and granulocyte inclusions with or without nephritis or sensorineural hearing loss	Enrichment	MYH9	1.01
932	Laryngomalacia	Enrichment	MECP2	1.01
933	Myotonia congenita, autosomal dominant	Enrichment	FAM131B	1.01
934	Retinoblastoma	Enrichment	RB1	1.01
935	Alagille syndrome 1	Enrichment	JAG1	1.01
936	Ataxia-telangiectasia	Enrichment	BRAF	1.01
937	Waardenburg syndrome, type 2a	Enrichment	POLR2F	1.01
938	Juvenile polyposis syndrome	Enrichment	SMAD4	1.01
939	Myotonia congenita, autosomal recessive	Enrichment	FAM131B	1.01
940	Sengers syndrome	Enrichment	AGK	1.01
941	Polycythemia vera	Enrichment	JAK2	1.01
942	Syndactyly, type iv	Enrichment	SHH	1.01
943	Watson syndrome	Enrichment	NF1	1.01
944	Periventricular nodular heterotopia 1	Enrichment	VWF	1.01
945	Menkes disease	Enrichment	EIF2AK3	1.01
946	Pierpont syndrome	Enrichment	TBL1XR1	1.01
947	Restrictive dermopathy 1	Enrichment	LMNA	1.01
948	Osteopetrosis, autosomal dominant 1	Enrichment	LRP5	1.01
949	Nuchal bleb, familial	Enrichment	SOS1	1.01
950	Neurofibromatosis, familial spinal	Enrichment	NF1	1.01
951	Neurodevelopmental disorder with spastic diplegia and visual defects	Enrichment	CTNNB1	1.01
952	Neutrophilic dermatosis, acute febrile	Enrichment	PTPN6	1.01
953	Lipodystrophy, familial partial, type 2	Enrichment	LMNA	1.01
954	Thrombocytopenia 5	Enrichment	ETV6	1.01
955	Cenani-lenz syndactyly syndrome	Enrichment	APC	1.01
956	Woolly hair, autosomal recessive 3	Enrichment	RB1	1.01
957	Chromosome 17q11.2 deletion syndrome, 1.4-mb	Enrichment	NF1	1.01
958	Ectodermal dysplasia 11b, hypohidrotic/hair/tooth type, autosomal recessive	Enrichment	RANBP2	1.01
959	Neurodevelopmental disorder with or without hypotonia, seizures, and cerebellar atrophy	Enrichment	SPTBN1	1.01
960	Neuropathy, hereditary sensory, type ie	Enrichment	DNMT1	1.01
961	Muscular dystrophy, congenital, lmna-related	Enrichment	LMNA	1.01
962	Anus, imperforate	Enrichment	CTNNB1	1.01
963	Microcephaly, developmental delay, and brittle hair syndrome	Enrichment	CARS1	1.01
964	Exudative vitreoretinopathy 7	Enrichment	CTNNB1	1.01
965	Intellectual developmental disorder, autosomal dominant 56	Enrichment	CLTC	1.01
966	Hypotrichosis 8	Enrichment	RB1	1.01
967	Inclusion body myopathy with paget disease of bone and frontotemporal dementia	Enrichment	VCP	1.01
968	Hyper ige syndrome	Enrichment	STAT3	1.01
969	High-grade b-cell lymphoma double-hit/triple-hit	Enrichment	MYC	1.01
970	Polycystic kidney disease 4	Enrichment	SHOC2	1.01
971	Nail disease	Enrichment	FZD6	1.01
972	Hypoplastic or aplastic tibia with polydactyly	Enrichment	SHH	1.01
973	Moyamoya disease 2	Enrichment	RNF213	1.01
974	Intraocular pressure quantitative trait locus	Enrichment	CREBBP	1.01
975	Intellectual developmental disorder, autosomal dominant 41	Enrichment	TBL1XR1	1.01
976	Brain cancer	Enrichment	NF1	1.01
977	Restrictive dermopathy	Enrichment	LMNA	1.01
978	Colon adenocarcinoma	Enrichment	APC	1.01
979	Bleeding disorder, platelet-type, 24	Enrichment	ITGB3	1.01
980	Cap myopathy	Enrichment	TPM3	1.01
981	Apc-associated polyposis conditions	Enrichment	APC	1.01
982	Hermansky-pudlak syndrome 1	Enrichment	AP3B1, ETV6	1.01
983	Body mass index quantitative trait locus 11	Enrichment	ADCY3, BDNF, PPARG	0.99
984	Alzheimer disease, familial, 1	Enrichment	PSEN1, VCP	0.96
985	Hereditary breast ovarian cancer syndrome	Enrichment	KRAS, NF1, PTEN, TP53	0.96
986	Dyskeratosis congenita, autosomal dominant 1	Enrichment	MECOM	0.96
987	Developmental dysplasia of the hip 1	Enrichment	PSMC3	0.96
988	Split-hand/foot malformation 1	Enrichment	FGFR2	0.96
989	Hemihyperplasia, isolated	Enrichment	PIK3CA	0.96
990	Wilms tumor, aniridia, genitourinary anomalies, and impaired intellectual development syndrome	Enrichment	BDNF	0.96
991	Type 1 diabetes mellitus	Enrichment	INS	0.96
992	Rare autosomal dominant non-syndromic sensorineural deafness type dfna	Enrichment	KITLG, PDE1C, REST	0.96
993	Undetermined early-onset epileptic encephalopathy	Enrichment	CLTC, CNKSR2, NTRK2, TRAK1	0.94
994	Erythrocytosis, familial, 1	Enrichment	JAK2	0.90
995	Hutchinson-gilford progeria syndrome	Enrichment	LMNA	0.90
996	Polydactyly, preaxial ii	Enrichment	SHH	0.90
997	Dowling-degos disease 1	Enrichment	ADAM10	0.90
998	Diffuse gastric and lobular breast cancer syndrome	Enrichment	KRAS	0.90
999	Ectodermal dysplasia 10b, hypohidrotic/hair/tooth type, autosomal recessive	Enrichment	RANBP2	0.90
1000	Trichohepatoenteric syndrome 1	Enrichment	AGK	0.90
1001	Emery-dreifuss muscular dystrophy 1, x-linked	Enrichment	LMNA	0.90
1002	Schizencephaly	Enrichment	SHH	0.90
1003	Budd-chiari syndrome	Enrichment	JAK2	0.90
1004	Microtia-anotia	Enrichment	LMNA	0.90
1005	Paget disease of bone 2, early-onset	Enrichment	SQSTM1	0.90
1006	Pilomatrixoma	Enrichment	CTNNB1	0.90
1007	Aminoacylase 1 deficiency	Enrichment	ACTB	0.90
1008	Lynch syndrome 4	Enrichment	RB1	0.90
1009	Alazami syndrome	Enrichment	CTNNB1	0.90
1010	Neurodevelopmental disorder with hypotonia and variable intellectual and behavioral abnormalities	Enrichment	POLR2A	0.90
1011	Emery-dreifuss muscular dystrophy	Enrichment	LMNA	0.90
1012	Dowling-degos disease	Enrichment	PSENEN	0.90
1013	Orofacial cleft	Enrichment	LRP6	0.90
1014	Ectodermal dysplasia	Enrichment	RANBP2	0.90
1015	Neurologic, endocrine, and pancreatic disease, multisystem, infantile-onset 1	Enrichment	CLTC	0.90
1016	Spastic quadriplegic cerebral palsy	Enrichment	KANK1	0.90
1017	Newborn respiratory distress syndrome	Enrichment	BRAF	0.90
1018	Epidermolytic nevus	Enrichment	HRAS	0.90
1019	2p21 microdeletion syndrome	Enrichment	PPM1B	0.90
1020	Paget's disease of bone 2	Enrichment	SQSTM1	0.90
1021	Eyelid coloboma	Enrichment	FZD5	0.90
1022	Intermediate nemaline myopathy	Enrichment	TPM3	0.90
1023	Vitreoretinopathy	Enrichment	LRP5	0.90
1024	Orofacial clefting syndrome	Enrichment	LRP6	0.90
1025	Lens coloboma	Enrichment	FZD5	0.90
1026	Pseudomyogenic hemangioendothelioma	Enrichment	ACTB	0.90
1027	Ventricular tachycardia, catecholaminergic polymorphic, 1, with or without atrial dysfunction and/or dilated cardiomyopathy	Enrichment	CALM1	0.90
1028	Polycystic kidney disease 1 with or without polycystic liver disease	Enrichment	TSC2	0.89
1029	Dyskeratosis congenita, autosomal dominant 2	Enrichment	MECOM	0.89
1030	Polycystic kidney disease 1	Enrichment	TSC2	0.89
1031	Megacolon	Enrichment	AKT3	0.89
1032	Hypophosphatemic rickets	Enrichment	FGF23	0.89
1033	Dilated cardiomyopathy	Enrichment	BRAF, KIF5B, LMNA, RAF1, VCL	0.89
1034	Ehlers-danlos syndrome	Enrichment	SMAD3, TGFBR2	0.88
1035	Macs syndrome	Enrichment	PORCN, SHH	0.85
1036	Arthrogryposis, distal, type 1a	Enrichment	MET	0.84
1037	Permanent neonatal diabetes mellitus	Enrichment	INS	0.84
1038	Isolated split hand-split foot malformation	Enrichment	SEM1	0.84
1039	Charcot-marie-tooth disease	Enrichment	DCTN1, LMNA, TFG	0.81
1040	Amyloidosis, hereditary systemic 2	Enrichment	FGA	0.81
1041	Dementia, lewy body	Enrichment	VCP	0.81
1042	Kearns-sayre syndrome	Enrichment	KIF5B	0.81
1043	Hypogonadotropic hypogonadism 1 with or without anosmia	Enrichment	POLR2F	0.81
1044	Polycystic kidney disease 3 with or without polycystic liver disease	Enrichment	SHOC2	0.81
1045	Norrie disease	Enrichment	FZD4	0.81
1046	Deafness, autosomal recessive 63	Enrichment	MYH9	0.81
1047	Hemophagocytic lymphohistiocytosis, familial, 1	Enrichment	PRF1	0.81
1048	Chondrosarcoma, extraskeletal myxoid	Enrichment	TFG	0.81
1049	Familial adenomatous polyposis 1	Enrichment	APC	0.81
1050	Charcot-marie-tooth disease, axonal, type 2e	Enrichment	VCP	0.81
1051	Rubinstein-taybi syndrome 2	Enrichment	EP300	0.81
1052	Glanzmann thrombasthenia 2	Enrichment	ITGB3	0.81
1053	Autosomal recessive limb-girdle muscular dystrophy type 2b	Enrichment	LMNA	0.81
1054	Persistent hyperplastic primary vitreous	Enrichment	FZD4	0.81
1055	Histiocytoid hemangioma	Enrichment	LMNA	0.81
1056	Aplasia cutis congenita	Enrichment	DLL4	0.81
1057	Autosomal recessive hypohidrotic ectodermal dysplasia syndrome	Enrichment	RANBP2	0.81
1058	Autosomal thrombocytopenia with normal platelets	Enrichment	ETV6	0.81
1059	Dementia	Enrichment	PSEN1	0.81
1060	Aggressive systemic mastocytosis	Enrichment	CBL	0.81
1061	Genetic motor neuron disease	Enrichment	DCTN1	0.81
1062	Hereditary persistence of fetal hemoglobin-sickle cell disease syndrome	Enrichment	BCL11A	0.81
1063	Generalized juvenile polyposis/juvenile polyposis coli	Enrichment	SMAD4	0.81
1064	Idiopathic aplastic anemia	Enrichment	PRF1	0.81
1065	Orofacial cleft 1	Enrichment	FGF10	0.79
1066	Hypogonadotropic hypogonadism	Enrichment	FGFR1	0.79
1067	Congenital central hypoventilation syndrome	Enrichment	BDNF	0.79
1068	Renal agenesis, bilateral	Enrichment	FGF20	0.79
1069	Attention deficit-hyperactivity disorder	Enrichment	KIF5B, MECP2	0.78
1070	Catecholaminergic polymorphic ventricular tachycardia 1	Enrichment	CALM1	0.78
1071	Leukemia, chronic lymphocytic	Enrichment	TP53	0.75
1072	Meier-gorlin syndrome 1	Enrichment	FGFR2	0.75
1073	Familial colorectal cancer	Enrichment	TP53	0.75
1074	Primary bone dysplasia	Enrichment	FGFR3	0.75
1075	Angelman syndrome	Enrichment	MECP2	0.74
1076	Coloboma of optic nerve	Enrichment	FZD5	0.74
1077	Emery-dreifuss muscular dystrophy 2, autosomal dominant	Enrichment	LMNA	0.74
1078	Weyers acrofacial dysostosis	Enrichment	CTNNB1	0.74
1079	Wolf-hirschhorn syndrome	Enrichment	CTBP1	0.74
1080	Telangiectasia, hereditary hemorrhagic, type 1	Enrichment	PSEN1	0.74
1081	Moyamoya disease 1	Enrichment	RNF213	0.74
1082	Waardenburg syndrome, type 4a	Enrichment	POLR2F	0.74
1083	Wilms tumor 5	Enrichment	BRAF	0.74
1084	Inflammatory bowel disease 25, autosomal recessive	Enrichment	TGFB1	0.74
1085	Inguinal hernia	Enrichment	RNF213	0.74
1086	Chronic mucocutaneous candidiasis	Enrichment	STAT1	0.74
1087	Hypertrichosis	Enrichment	CREBBP	0.74
1088	Classic ehlers-danlos syndrome	Enrichment	TGFBR1	0.74
1089	Waardenburg syndrome	Enrichment	POLR2F	0.74
1090	Cardiomyopathy, familial hypertrophic, 1	Enrichment	LMNA, RAF1	0.72
1091	Autoinflammatory disease	Enrichment	AP3B1, PRF1	0.72
1092	Scoliosis	Enrichment	CREBBP, PTPN11	0.72
1093	Migraine with or without aura 1	Enrichment	ESR1	0.71
1094	Myelodysplastic syndrome	Enrichment	TP53	0.71
1095	46,xy complete gonadal dysgenesis	Enrichment	CBX2	0.71
1096	Osteochondrodysplasia	Enrichment	FGFR3	0.71
1097	Diabetes mellitus	Enrichment	INS	0.71
1098	Uterine corpus cancer	Enrichment	PTEN	0.71
1099	West syndrome	Enrichment	NTRK2, TSC2	0.68
1100	Epicanthus	Enrichment	PTPN11	0.68
1101	Renal hypodysplasia/aplasia 3	Enrichment	FGFR3	0.68
1102	Bethlem myopathy 1a	Enrichment	LMNA	0.68
1103	Waardenburg syndrome, type 1	Enrichment	POLR2F	0.68
1104	Mitochondrial dna depletion syndrome 4a	Enrichment	RANBP2	0.68
1105	Thrombophilia due to thrombin defect	Enrichment	FGA	0.68
1106	Rett syndrome	Enrichment	MECP2	0.68
1107	Coats disease	Enrichment	FZD4	0.68
1108	Semantic dementia	Enrichment	PSEN1	0.68
1109	Hereditary sensory and autonomic neuropathy type 1	Enrichment	DNMT1	0.68
1110	Renal cell carcinoma with mit translocations	Enrichment	CLTC	0.68
1111	Hereditary hemorrhagic telangiectasia	Enrichment	SMAD4	0.68
1112	Focal epilepsy	Enrichment	MECP2	0.68
1113	Childhood-onset nemaline myopathy	Enrichment	TPM3	0.68
1114	Moyamoya angiopathy	Enrichment	RNF213	0.68
1115	Brugada syndrome	Enrichment	AKAP9, LMNA	0.67
1116	Spastic paraplegia 4, autosomal dominant	Enrichment	FGG	0.62
1117	Fanconi anemia, complementation group c	Enrichment	HDAC8	0.62
1118	Polycystic kidney disease 4 with or without polycystic liver disease	Enrichment	SHOC2	0.62
1119	Ewing sarcoma	Enrichment	NF1	0.62
1120	Rett syndrome, congenital variant	Enrichment	MECP2	0.62
1121	Mitochondrial dna depletion syndrome 4b	Enrichment	RANBP2	0.62
1122	Congenital muscular dystrophy	Enrichment	LMNA	0.62
1123	Neuroblastoma	Enrichment	ALK	0.62
1124	Myocarditis	Enrichment	LMNA	0.62
1125	Hypoplastic left heart syndrome	Enrichment	NOTCH1	0.62
1126	Hypogonadotropic hypogonadism 7 with or without anosmia	Enrichment	FGFR1	0.62
1127	Cleft lip/palate	Enrichment	PDGFRA	0.62
1128	Wilms tumor 1	Enrichment	REST	0.60
1129	Autosomal dominant polycystic kidney disease	Enrichment	TSC2	0.60
1130	Cornelia de lange syndrome 1	Enrichment	HDAC8	0.58
1131	Cardiomyopathy, familial hypertrophic, 4	Enrichment	BRAF	0.58
1132	Rheumatoid arthritis	Enrichment	IL10	0.58
1133	Charge syndrome	Enrichment	EP300	0.58
1134	Arrhythmogenic right ventricular dysplasia, familial, 9	Enrichment	LMNA	0.58
1135	Ventricular septal defect	Enrichment	BRAF	0.58
1136	Colonic benign neoplasm	Enrichment	APC	0.58
1137	Cornelia de lange syndrome	Enrichment	HDAC8	0.58
1138	Familial thoracic aortic aneurysm and dissection	Enrichment	SMAD3	0.58
1139	Trichothiodystrophy	Enrichment	CARS1	0.58
1140	Hypertelorism	Enrichment	FGFR2, PIK3CA	0.58
1141	Isolated congenital microcephaly	Enrichment	PHC1	0.57
1142	Multiple sclerosis	Enrichment	ITPR1	0.57
1143	Amyotrophic lateral sclerosis 1	Enrichment	DCTN1	0.54
1144	Aplastic anemia	Enrichment	PRF1	0.54
1145	Nephrocalcinosis	Enrichment	RNF213	0.54
1146	Nemaline myopathy	Enrichment	TPM3	0.54
1147	Anterior segment dysgenesis	Enrichment	ITPR1	0.54
1148	Severe combined immunodeficiency	Enrichment	LCK, ZAP70	0.52
1149	Combined immunodeficiency	Enrichment	ZAP70	0.51
1150	Atrial heart septal defect	Enrichment	HDAC8	0.51
1151	Movement disease	Enrichment	CLCN6	0.51
1152	Combined t cell and b cell immunodeficiency	Enrichment	ZAP70	0.51
1153	Interatrial communication	Enrichment	HDAC8	0.51
1154	Combined t and b cell immunodeficiency	Enrichment	ZAP70	0.51
1155	Cakut	Enrichment	ACTG1, ZMYM2	0.50
1156	Primary ovarian insufficiency	Enrichment	JAK2, KDR, RICTOR	0.50
1157	Sudden infant death syndrome	Enrichment	CALM2	0.49
1158	Rare autosomal recessive non-syndromic sensorineural deafness type dfnb	Enrichment	ADCY1, HGF, MET	0.49
1159	Maturity-onset diabetes of the young	Enrichment	INS	0.49
1160	Dystonia	Enrichment	CAMK2B, MECP2	0.49
1161	Cardiac conduction defect	Enrichment	LMNA	0.48
1162	Muscular dystrophy, limb-girdle, autosomal recessive 2	Enrichment	LMNA	0.48
1163	Inherited isolated arrhythmogenic ventricular dysplasia, biventricular variant	Enrichment	LMNA	0.48
1164	Inherited isolated arrhythmogenic cardiomyopathy, dominant-left variant	Enrichment	LMNA	0.48
1165	Non-syndromic x-linked intellectual disability	Enrichment	CNKSR2, MECP2	0.47
1166	Microphthalmia/coloboma 12	Enrichment	FZD5	0.45
1167	Diaphragmatic hernia, congenital	Enrichment	CDK8	0.45
1168	Stereotypic movement disorder	Enrichment	MECP2	0.45
1169	Protein-deficiency anemia	Enrichment	NRAS	0.45
1170	Diamond-blackfan anemia 1	Enrichment	TP53	0.44
1171	Systemic lupus erythematosus	Enrichment	IL10, MECP2	0.43
1172	Pheochromocytoma	Enrichment	NF1	0.42
1173	Heart disease	Enrichment	CREBBP	0.42
1174	Inherited isolated arrhythmogenic cardiomyopathy, dominant-right variant	Enrichment	LMNA	0.42
1175	Pituitary stalk interruption syndrome	Enrichment	DNMT1	0.42
1176	46,xy partial gonadal dysgenesis	Enrichment	SOS1	0.42
1177	Coloboma of macula	Enrichment	FZD5	0.40
1178	Congenital myopathy 4a, autosomal dominant	Enrichment	TPM3	0.40
1179	Hermansky-pudlak syndrome	Enrichment	AP3B1	0.40
1180	Male infertility with spermatogenesis disorder	Enrichment	SPRED1	0.40
1181	Strabismus	Enrichment	PTPN11	0.39
1182	Cerebellar hypoplasia/atrophy, epilepsy, and global developmental delay	Enrichment	BCL11A	0.38
1183	Hydrocephalus, congenital, 1	Enrichment	CDK8	0.38
1184	Arrhythmogenic right ventricular cardiomyopathy	Enrichment	LMNA	0.38
1185	Hypertension	Enrichment	MYH9	0.38
1186	Nephrotic syndrome	Enrichment	ATIC, FN1	0.37
1187	Hypertrophic cardiomyopathy	Enrichment	KIF5B, PTPN11	0.37
1188	Jeune thoracic dystrophy	Enrichment	GRK2	0.36
1189	Melanoma, cutaneous malignant 1	Enrichment	BRAF	0.36
1190	Cleft palate, isolated	Enrichment	AMER1	0.36
1191	Cardiomyopathy, dilated, 1e	Enrichment	LMNA	0.36
1192	Cataract 44	Enrichment	AGK	0.36
1193	Human immunodeficiency virus type 1	Enrichment	IL10	0.34
1194	Neuromuscular disease	Enrichment	LMNA	0.34
1195	Polycystic kidney disease	Enrichment	HDAC8	0.34
1196	Primary autosomal recessive microcephaly	Enrichment	PHC1	0.33
1197	Asphyxiating thoracic dystrophy	Enrichment	GRK2	0.33
1198	Behcet syndrome	Enrichment	IL10	0.32
1199	Esophageal atresia/tracheoesophageal fistula	Enrichment	POLR2B	0.32
1200	Dyskeratosis congenita	Enrichment	NPM1	0.32
1201	Rare genetic deafness	Enrichment	ACTG1, MYH9, POLR2F	0.31
1202	Diamond-blackfan anemia	Enrichment	TP53	0.30
1203	Cardiomyopathy, dilated, 1a	Enrichment	LMNA	0.29
1204	Lissencephaly	Enrichment	ACTG1	0.29
1205	Centronuclear myopathy	Enrichment	TPM3	0.29
1206	Hereditary paraganglioma-pheochromocytoma syndromes	Enrichment	NF1	0.29
1207	Short-rib thoracic dysplasia 1 with or without polydactyly	Enrichment	GRK2	0.28
1208	Cerebral palsy	Enrichment	PDGFRB	0.27
1209	Brittle bone disorder	Enrichment	LRP5	0.27
1210	Muscular dystrophy	Enrichment	LMNA	0.25
1211	Autosomal recessive non-syndromic intellectual disability	Enrichment	CLIP1, TPR	0.24
1212	Epilepsy	Enrichment	NBEA	0.22
1213	Sensorineural hearing loss	Enrichment	HGF	0.22
1214	Joubert syndrome 1	Enrichment	RCOR1	0.21
1215	Cystic fibrosis	Enrichment	TGFB1	0.18
1216	Peripheral nervous system disease	Enrichment	LMNA	0.18
1217	Neuropathy	Enrichment	LMNA	0.18
1218	Familial hypertrophic cardiomyopathy	Enrichment	RAF1	0.17
1219	Spastic ataxia	Enrichment	ITPR1	0.15
1220	Non-syndromic genetic deafness	Enrichment	ACTG1	0.15
1221	Myopathy	Enrichment	TPM3	0.13
1222	Hereditary spastic paraplegia	Enrichment	ERLIN2	0.12
1223	Nonsyndromic hearing loss	Enrichment	ACTG1	0.12
1224	Primary ciliary dyskinesia	Enrichment	PRKAR1B	0.08
1225	Schizophrenia	Enrichment	BIRC6	0.06
1226	Deafness, autosomal recessive	Enrichment	MYH9	0.05
1227	Autosomal recessive nonsyndromic deafness	Enrichment	MYH9	0.05
1228	Mitochondrial disease	Enrichment	AGK	0.02
1229	Hereditary retinal dystrophy	Enrichment	FZD4, JAG1, KIAA1549, LRP5	0.01
1230	Fundus dystrophy	Enrichment	FZD4, JAG1, KIAA1549, LRP5	0.01
1231	Retinitis pigmentosa	Enrichment	KIAA1549	0.00

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

PIP3 activates AKT signaling

Pathway Network for PIP3 activates AKT signaling

Pathway network for the PIP3 activates AKT signaling SuperPath

Member Pathways for PIP3 activates AKT signaling

Pathways in the PIP3 activates AKT signaling SuperPath

Gene overlap in member pathways for PIP3 activates AKT signaling SuperPath

Associated Genes for PIP3 activates AKT signaling

Associated Disorders for PIP3 activates AKT signaling

Disorders associated with PIP3 activates AKT signaling SuperPath

STRING Interaction Network for PIP3 activates AKT signaling

Sources for PIP3 activates AKT signaling