Potassium Channels

Pathway network for the Potassium Channels SuperPath

Sources:

Reactome

Pathways in the Potassium Channels SuperPath

#	Name	Source	Genes
1	Potassium Channels	Reactome	ABCC8 ABCC9 GABBR1 GABBR2 GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNGT1 GNGT2 HCN1 HCN2 HCN3 HCN4 KCNA1 KCNA10 KCNA2 KCNA3 KCNA4 KCNA5 KCNA6 KCNA7 KCNAB1 KCNAB2 KCNAB3 KCNB1 KCNB2 KCNC1 KCNC2 KCNC3 KCNC4 KCND1 KCND2 KCND3 KCNF1 KCNG1 KCNG2 KCNG3 KCNG4 KCNH1 KCNH2 KCNH3 KCNH4 KCNH5 KCNH6 KCNH7 KCNH8 KCNJ1 KCNJ10 KCNJ11 KCNJ12 KCNJ14 KCNJ15 KCNJ16 KCNJ2 KCNJ3 KCNJ4 KCNJ5 KCNJ6 KCNJ8 KCNJ9 KCNK1 KCNK10 KCNK13 KCNK16 KCNK17 KCNK18 KCNK2 KCNK3 KCNK4 KCNK6 KCNK7 KCNK9 KCNMA1 KCNMB1 KCNMB2 KCNMB3 KCNMB4 KCNN1 KCNN2 KCNN3 KCNN4 KCNQ1 KCNQ2 KCNQ3 KCNQ4 KCNQ5 KCNS1 KCNS2 KCNS3 KCNV1 KCNV2 (see all 103) (see less)
2	Voltage gated Potassium channels	Reactome	KCNA1 KCNA10 KCNA2 KCNA3 KCNA4 KCNA5 KCNA6 KCNA7 KCNAB1 KCNAB2 KCNAB3 KCNB1 KCNB2 KCNC1 KCNC2 KCNC3 KCNC4 KCND1 KCND2 KCND3 KCNF1 KCNG1 KCNG2 KCNG3 KCNG4 KCNH1 KCNH2 KCNH3 KCNH4 KCNH5 KCNH6 KCNH7 KCNH8 KCNQ1 KCNQ2 KCNQ3 KCNQ4 KCNQ5 KCNS1 KCNS2 KCNS3 KCNV1 KCNV2 (see all 43) (see less)
3	Ca2+ activated K+ channels	Reactome	KCNMA1 KCNMB1 KCNMB2 KCNMB3 KCNMB4 KCNN1 KCNN2 KCNN3 KCNN4 (see all 9) (see less)
4	HCN channels	Reactome	HCN1 HCN2 HCN3 HCN4

Gene overlap in member pathways for Potassium Channels SuperPath

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	HCN4	Hyperpolarization Activated Cyclic Nucleotide Gated Potassium Channel 4	Protein Coding	2
2	KCNMB2	Potassium Calcium-Activated Channel Subfamily M Regulatory Beta Subunit 2	Protein Coding	2
3	KCNH8	Potassium Voltage-Gated Channel Subfamily H Member 8	Protein Coding	2
4	KCNV2	Potassium Voltage-Gated Channel Modifier Subfamily V Member 2	Protein Coding	2
5	KCNG3	Potassium Voltage-Gated Channel Modifier Subfamily G Member 3	Protein Coding	2
6	KCNH4	Potassium Voltage-Gated Channel Subfamily H Member 4	Protein Coding	2
7	KCNH3	Potassium Voltage-Gated Channel Subfamily H Member 3	Protein Coding	2
8	KCNG2	Potassium Voltage-Gated Channel Modifier Subfamily G Member 2	Protein Coding	2
9	KCNV1	Potassium Voltage-Gated Channel Modifier Subfamily V Member 1	Protein Coding	2
10	KCNMB3	Potassium Calcium-Activated Channel Subfamily M Regulatory Beta Subunit 3	Protein Coding	2
11	KCNH5	Potassium Voltage-Gated Channel Subfamily H Member 5	Protein Coding	2
12	KCNMB4	Potassium Calcium-Activated Channel Subfamily M Regulatory Beta Subunit 4	Protein Coding	2
13	HCN1	Hyperpolarization Activated Cyclic Nucleotide Gated Potassium Channel 1	Protein Coding	2
14	KCNA1	Potassium Voltage-Gated Channel Subfamily A Member 1	Protein Coding	2
15	KCNA2	Potassium Voltage-Gated Channel Subfamily A Member 2	Protein Coding	2
16	KCNA3	Potassium Voltage-Gated Channel Subfamily A Member 3	Protein Coding	2
17	KCNA4	Potassium Voltage-Gated Channel Subfamily A Member 4	Protein Coding	2
18	KCNA5	Potassium Voltage-Gated Channel Subfamily A Member 5	Protein Coding	2
19	KCNA6	Potassium Voltage-Gated Channel Subfamily A Member 6	Protein Coding	2
20	KCNA7	Potassium Voltage-Gated Channel Subfamily A Member 7	Protein Coding	2
21	KCNA10	Potassium Voltage-Gated Channel Subfamily A Member 10	Protein Coding	2
22	KCNB1	Potassium Voltage-Gated Channel Subfamily B Member 1	Protein Coding	2
23	KCNC1	Potassium Voltage-Gated Channel Subfamily C Member 1	Protein Coding	2
24	KCNC2	Potassium Voltage-Gated Channel Subfamily C Member 2	Protein Coding	2
25	KCNC3	Potassium Voltage-Gated Channel Subfamily C Member 3	Protein Coding	2
26	KCNC4	Potassium Voltage-Gated Channel Subfamily C Member 4	Protein Coding	2
27	KCND1	Potassium Voltage-Gated Channel Subfamily D Member 1	Protein Coding	2
28	KCND2	Potassium Voltage-Gated Channel Subfamily D Member 2	Protein Coding	2
29	KCND3	Potassium Voltage-Gated Channel Subfamily D Member 3	Protein Coding	2
30	KCNF1	Potassium Voltage-Gated Channel Modifier Subfamily F Member 1	Protein Coding	2
31	KCNG1	Potassium Voltage-Gated Channel Modifier Subfamily G Member 1	Protein Coding	2
32	KCNH1	Potassium Voltage-Gated Channel Subfamily H Member 1	Protein Coding	2
33	KCNH2	Potassium Voltage-Gated Channel Subfamily H Member 2	Protein Coding	2
34	KCNMA1	Potassium Calcium-Activated Channel Subfamily M Alpha 1	Protein Coding	2
35	KCNMB1	Potassium Calcium-Activated Channel Subfamily M Regulatory Beta Subunit 1	Protein Coding	2
36	KCNN1	Potassium Calcium-Activated Channel Subfamily N Member 1	Protein Coding	2
37	KCNN2	Potassium Calcium-Activated Channel Subfamily N Member 2	Protein Coding	2
38	KCNN3	Potassium Calcium-Activated Channel Subfamily N Member 3	Protein Coding	2
39	KCNN4	Potassium Calcium-Activated Channel Subfamily N Member 4	Protein Coding	2
40	KCNQ1	Potassium Voltage-Gated Channel Subfamily Q Member 1	Protein Coding	2
41	KCNQ2	Potassium Voltage-Gated Channel Subfamily Q Member 2	Protein Coding	2
42	KCNQ3	Potassium Voltage-Gated Channel Subfamily Q Member 3	Protein Coding	2
43	KCNS1	Potassium Voltage-Gated Channel Modifier Subfamily S Member 1	Protein Coding	2
44	KCNS2	Potassium Voltage-Gated Channel Modifier Subfamily S Member 2	Protein Coding	2
45	KCNS3	Potassium Voltage-Gated Channel Modifier Subfamily S Member 3	Protein Coding	2
46	KCNQ5	Potassium Voltage-Gated Channel Subfamily Q Member 5	Protein Coding	2
47	HCN3	Hyperpolarization Activated Cyclic Nucleotide Gated Potassium Channel 3	Protein Coding	2
48	HCN2	Hyperpolarization Activated Cyclic Nucleotide Gated Potassium And Sodium Channel 2	Protein Coding	2
49	KCNAB1	Potassium Voltage-Gated Channel Subfamily A Regulatory Beta Subunit 1	Protein Coding	2
50	KCNH6	Potassium Voltage-Gated Channel Subfamily H Member 6	Protein Coding	2
51	KCNAB2	Potassium Voltage-Gated Channel Subfamily A Regulatory Beta Subunit 2	Protein Coding	2
52	KCNH7	Potassium Voltage-Gated Channel Subfamily H Member 7	Protein Coding	2
53	KCNQ4	Potassium Voltage-Gated Channel Subfamily Q Member 4	Protein Coding	2
54	KCNAB3	Potassium Voltage-Gated Channel Subfamily A Regulatory Beta Subunit 3	Protein Coding	2
55	KCNG4	Potassium Voltage-Gated Channel Modifier Subfamily G Member 4	Protein Coding	2
56	KCNB2	Potassium Voltage-Gated Channel Subfamily B Member 2	Protein Coding	2
57	ABCC9	ATP Binding Cassette Subfamily C Member 9	Protein Coding	1
58	KCNK7	Potassium Two Pore Domain Channel Subfamily K Member 7	Protein Coding	1
59	GNB5	G Protein Subunit Beta 5	Protein Coding	1
60	GABBR1	Gamma-Aminobutyric Acid Type B Receptor Subunit 1	Protein Coding	1
61	GNB1	G Protein Subunit Beta 1	Protein Coding	1
62	GNB2	G Protein Subunit Beta 2	Protein Coding	1
63	GNB3	G Protein Subunit Beta 3	Protein Coding	1
64	GNG3	G Protein Subunit Gamma 3	Protein Coding	1
65	GNG4	G Protein Subunit Gamma 4	Protein Coding	1
66	GNG5	G Protein Subunit Gamma 5	Protein Coding	1
67	GNG7	G Protein Subunit Gamma 7	Protein Coding	1
68	GNG10	G Protein Subunit Gamma 10	Protein Coding	1
69	GNG11	G Protein Subunit Gamma 11	Protein Coding	1
70	GNGT1	G Protein Subunit Gamma Transducin 1	Protein Coding	1
71	GNGT2	G Protein Subunit Gamma Transducin 2	Protein Coding	1
72	KCNK18	Potassium Two Pore Domain Channel Subfamily K Member 18	Protein Coding	1
73	KCNJ1	Potassium Inwardly Rectifying Channel Subfamily J Member 1	Protein Coding	1
74	KCNJ2	Potassium Inwardly Rectifying Channel Subfamily J Member 2	Protein Coding	1
75	KCNJ3	Potassium Inwardly Rectifying Channel Subfamily J Member 3	Protein Coding	1
76	KCNJ4	Potassium Inwardly Rectifying Channel Subfamily J Member 4	Protein Coding	1
77	KCNJ5	Potassium Inwardly Rectifying Channel Subfamily J Member 5	Protein Coding	1
78	KCNJ6	Potassium Inwardly Rectifying Channel Subfamily J Member 6	Protein Coding	1
79	KCNJ8	Potassium Inwardly Rectifying Channel Subfamily J Member 8	Protein Coding	1
80	KCNJ9	Potassium Inwardly Rectifying Channel Subfamily J Member 9	Protein Coding	1
81	KCNJ10	Potassium Inwardly Rectifying Channel Subfamily J Member 10	Protein Coding	1
82	KCNJ11	Potassium Inwardly Rectifying Channel Subfamily J Member 11	Protein Coding	1
83	KCNJ12	Potassium Inwardly Rectifying Channel Subfamily J Member 12	Protein Coding	1
84	KCNJ14	Potassium Inwardly Rectifying Channel Subfamily J Member 14	Protein Coding	1
85	KCNJ15	Potassium Inwardly Rectifying Channel Subfamily J Member 15	Protein Coding	1
86	KCNJ16	Potassium Inwardly Rectifying Channel Subfamily J Member 16	Protein Coding	1
87	KCNK1	Potassium Two Pore Domain Channel Subfamily K Member 1	Protein Coding	1
88	KCNK2	Potassium Two Pore Domain Channel Subfamily K Member 2	Protein Coding	1
89	KCNK3	Potassium Two Pore Domain Channel Subfamily K Member 3	Protein Coding	1
90	KCNK4	Potassium Two Pore Domain Channel Subfamily K Member 4	Protein Coding	1
91	KCNK9	Potassium Two Pore Domain Channel Subfamily K Member 9	Protein Coding	1
92	GNG13	G Protein Subunit Gamma 13	Protein Coding	1
93	KCNK10	Potassium Two Pore Domain Channel Subfamily K Member 10	Protein Coding	1
94	GNG2	G Protein Subunit Gamma 2	Protein Coding	1
95	GNG12	G Protein Subunit Gamma 12	Protein Coding	1
96	KCNK13	Potassium Two Pore Domain Channel Subfamily K Member 13	Protein Coding	1
97	GNB4	G Protein Subunit Beta 4	Protein Coding	1
98	ABCC8	ATP Binding Cassette Subfamily C Member 8	Protein Coding	1
99	KCNK16	Potassium Two Pore Domain Channel Subfamily K Member 16	Protein Coding	1
100	KCNK17	Potassium Two Pore Domain Channel Subfamily K Member 17	Protein Coding	1
101	GNG8	G Protein Subunit Gamma 8	Protein Coding	1
102	KCNK6	Potassium Two Pore Domain Channel Subfamily K Member 6	Protein Coding	1
103	GABBR2	Gamma-Aminobutyric Acid Type B Receptor Subunit 2	Protein Coding	1

Disorders associated with Potassium Channels SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Familial atrial fibrillation	Enrichment	ABCC9, KCNA5, KCNJ2, KCNJ3, KCNJ5, KCNQ1	7.70
2	Brugada syndrome	Enrichment	ABCC9, HCN4, KCND3, KCNH2, KCNJ8	5.88
3	Congenital short qt syndrome	Enrichment	KCNH2, KCNJ2, KCNQ1	5.38
4	Developmental and epileptic encephalopathy	Enrichment	KCNB1, KCNC2, KCNH5, KCNQ2	5.32
5	Seizures, benign familial neonatal, 2	Enrichment	KCNQ2, KCNQ3	5.01
6	Self-limited neonatal epilepsy	Enrichment	KCNQ2, KCNQ3	5.01
7	Andersen cardiodysrhythmic periodic paralysis	Enrichment	KCNJ2, KCNJ5	4.24
8	Long qt syndrome 2	Enrichment	KCNH2, KCNQ1	4.23
9	Undetermined early-onset epileptic encephalopathy	Enrichment	GABBR2, HCN1, KCNA2, KCNB1, KCNC2	4.19
10	Epicanthus	Enrichment	ABCC9, KCNA6, KCNQ2	4.05
11	Self-limited infantile epilepsy	Enrichment	KCNQ2, KCNQ3	4.01
12	Zimmermann-laband syndrome 1	Enrichment	KCNH1, KCNN3	3.77
13	Cantu syndrome	Enrichment	ABCC9, KCNJ8	3.77
14	Paroxysmal nonkinesigenic dyskinesia 3 with or without generalized epilepsy	Enrichment	KCNA1, KCNMA1	3.77
15	Dend syndrome	Enrichment	ABCC8, KCNJ11	3.77
16	Sick sinus syndrome 2	Enrichment	HCN4	3.53
17	Epilepsy, idiopathic generalized 17	Enrichment	HCN2	3.53
18	Epilepsy, idiopathic generalized 18	Enrichment	HCN4	3.53
19	Familial febrile seizures 2	Enrichment	HCN2	3.53
20	Developmental and epileptic encephalopathy 24	Enrichment	HCN1	3.53
21	Generalized epilepsy with febrile seizures plus, type 10	Enrichment	HCN1	3.53
22	Episodic kinesigenic dyskinesia 1	Enrichment	KCNA1, KCNJ10	3.47
23	Neonatal diabetes mellitus	Enrichment	ABCC8, KCNJ11	3.47
24	Familial sick sinus syndrome	Enrichment	GNB2, HCN4	3.47
25	Autosomal dominant non-syndromic intellectual disability	Enrichment	GABBR1, GNB1, KCNQ2, KCNQ5	3.26
26	Transient neonatal diabetes mellitus	Enrichment	ABCC8, KCNJ11	3.25
27	Hypoglycemia	Enrichment	ABCC8, KCNJ11	3.25
28	Congenital long qt syndrome	Enrichment	KCNH2, KCNQ1	3.20
29	Dehydrated hereditary stomatocytosis 2	Enrichment	KCNN4	3.18
30	Epilepsy, idiopathic generalized 16	Enrichment	KCNMA1	3.18
31	Cerebellar atrophy, developmental delay, and seizures	Enrichment	KCNMA1	3.18
32	Zimmermann-laband syndrome 3	Enrichment	KCNN3	3.18
33	Hyperinsulinemic hypoglycemia, familial, 1	Enrichment	ABCC8, KCNJ11	3.08
34	Nonsyndromic genetic hyperinsulinism	Enrichment	ABCC8, KCNJ11	3.08
35	Brugada syndrome 8	Enrichment	HCN4	3.05
36	Color blindness	Enrichment	HCN1	2.93
37	Hypertension, diastolic	Enrichment	KCNMB1	2.88
38	Neurodevelopmental disorder with or without variable movement or behavioral abnormalities	Enrichment	KCNN2	2.88
39	Dystonia 34, myoclonic	Enrichment	KCNN2	2.88
40	Liang-wang syndrome	Enrichment	KCNMA1	2.88
41	Long qt syndrome 1	Enrichment	KCNH2, KCNJ5, KCNQ1	2.83
42	Permanent neonatal diabetes mellitus	Enrichment	ABCC8, KCNJ11	2.81
43	Long qt syndrome	Enrichment	KCNH2, KCNJ5, KCNQ1	2.79
44	Dehydrated hereditary stomatocytosis 1 with or without pseudohyperkalemia and/or perinatal edema	Enrichment	KCNN4	2.58
45	Developmental and epileptic encephalopathy 1	Enrichment	KCNA2, KCNQ2	2.55
46	Episodic ataxia, type 1	Enrichment	KCNA1	2.50
47	Atrial fibrillation, familial, 7	Enrichment	KCNA5	2.50
48	Cone dystrophy with supernormal rod responses	Enrichment	KCNV2	2.50
49	Nipples inverted	Enrichment	KCNA6	2.50
50	Temple-baraitser syndrome	Enrichment	KCNH1	2.50
51	Developmental and epileptic encephalopathy 7	Enrichment	KCNQ2	2.50
52	Short qt syndrome 1	Enrichment	KCNH2	2.50
53	Epilepsy, progressive myoclonic 7	Enrichment	KCNC1	2.50
54	Developmental and epileptic encephalopathy 26	Enrichment	KCNB1	2.50
55	Developmental and epileptic encephalopathy 32	Enrichment	KCNA2	2.50
56	Spinocerebellar ataxia 19	Enrichment	KCND3	2.50
57	Developmental and epileptic encephalopathy 103	Enrichment	KCNC2	2.50
58	Brugada syndrome 9	Enrichment	KCND3	2.50
59	Microcephaly, cataracts, impaired intellectual development, and dystonia with abnormal striatum	Enrichment	KCNA4	2.50
60	Kcnq3-related disorders	Enrichment	KCNQ3	2.50
61	Spinocerebellar ataxia type 19/22	Enrichment	KCND3	2.50
62	Developmental and epileptic encephalopathy 112	Enrichment	KCNH5	2.50
63	Hereditary continuous muscle fiber activity	Enrichment	KCNA1	2.50
64	Kcnq2-related disorders	Enrichment	KCNQ2	2.50
65	Cone dystrophy with supernormal rod response	Enrichment	KCNV2	2.50
66	Isolated autosomal dominant hypomagnesemia, glaudemans type	Enrichment	KCNA1	2.50
67	Generalized epilepsy with febrile seizures plus	Enrichment	HCN1	2.38
68	Seizures, benign familial neonatal, 1	Enrichment	KCNQ2	2.20
69	Deafness, autosomal dominant 2a	Enrichment	KCNQ4	2.20
70	Seizures, benign familial infantile, 3	Enrichment	KCNQ2	2.20
71	Spinocerebellar ataxia 13	Enrichment	KCNC3	2.20
72	Intellectual developmental disorder, autosomal dominant 46	Enrichment	KCNQ5	2.20
73	Cardiovascular system disease	Enrichment	KCNQ1	2.20
74	Benign familial neonatal epilepsy	Enrichment	KCNQ3	2.20
75	Ichthyosis, congenital, autosomal recessive 10	Enrichment	KCNQ2	2.20
76	Seizures, benign familial infantile, 5	Enrichment	KCNQ3	2.20
77	Dfna2 nonsyndromic hearing loss	Enrichment	KCNQ4	2.20
78	Jervell-lange nielsen syndrome	Enrichment	KCNQ1	2.20
79	Benign neonatal seizures	Enrichment	KCNQ3	2.20
80	Wolff-parkinson-white syndrome	Enrichment	ABCC9, KCNQ1	2.19
81	Sudden infant death syndrome	Enrichment	KCNJ8, KCNQ1	2.14
82	Bartter syndrome, type 2, antenatal	Enrichment	KCNJ1	2.12
83	Hyperinsulinemic hypoglycemia, familial, 2	Enrichment	KCNJ11	2.12
84	Long qt syndrome 13	Enrichment	KCNJ5	2.12
85	Short qt syndrome 3	Enrichment	KCNJ2	2.12
86	Neurodevelopmental disorder with hypotonia and dysmorphic facies	Enrichment	GNB2	2.12
87	Intellectual disability and myopathy syndrome	Enrichment	ABCC9	2.12
88	Hypokalemic tubulopathy and deafness	Enrichment	KCNJ16	2.12
89	Maturity-onset diabetes of the young, type 12	Enrichment	ABCC8	2.12
90	Neurodevelopmental disorder with poor language and loss of hand skills	Enrichment	GABBR2	2.12
91	Developmental and epileptic encephalopathy 59	Enrichment	GABBR2	2.12
92	Hyperaldosteronism, familial, type iii	Enrichment	KCNJ5	2.12
93	Diabetes mellitus, transient neonatal, 3	Enrichment	KCNJ11	2.12
94	Seizures, sensorineural deafness, ataxia, impaired intellectual development, and electrolyte imbalance	Enrichment	KCNJ10	2.12
95	Lodder-merla syndrome, type 2, with developmental delay and with or without cardiac arrhythmia	Enrichment	GNB5	2.12
96	Migraine with aura 13	Enrichment	KCNK18	2.12
97	Diabetes mellitus, permanent neonatal, 2	Enrichment	KCNJ11	2.12
98	Pulmonary hypertension, primary, 4	Enrichment	KCNK3	2.12
99	Charcot-marie-tooth disease, dominant intermediate f	Enrichment	GNB4	2.12
100	Maturity-onset diabetes of the young, type 13	Enrichment	KCNJ11	2.12
101	Atrial fibrillation, familial, 9	Enrichment	KCNJ2	2.12
102	Autosomal dominant hyperinsulinism due to sur1 deficiency	Enrichment	ABCC8	2.12
103	Intellectual developmental disorder, autosomal dominant 42	Enrichment	GNB1	2.12
104	Sick sinus syndrome 4	Enrichment	GNB2	2.12
105	Neurodevelopmental disorder with language delay and variable cognitive abnormalities	Enrichment	GABBR1	2.12
106	Diazoxide-resistant focal hyperinsulinism due to sur1 deficiency	Enrichment	ABCC8	2.12
107	Congestive heart failure	Enrichment	ABCC8	2.12
108	Intermediate dend syndrome	Enrichment	KCNJ11	2.12
109	Diazoxide-resistant focal hyperinsulinism due to kir6.2 deficiency	Enrichment	KCNJ11	2.12
110	Rare renal tubular disease	Enrichment	KCNJ10	2.12
111	Autosomal recessive hyperinsulinism due to sur1 deficiency	Enrichment	ABCC8	2.12
112	Autosomal dominant hyperinsulinism due to kir6.2 deficiency	Enrichment	KCNJ11	2.12
113	Autosomal recessive hyperinsulinism due to kir6.2 deficiency	Enrichment	KCNJ11	2.12
114	West syndrome	Enrichment	KCNA2, KCNQ2	2.07
115	Atrial fibrillation, familial, 3	Enrichment	KCNQ1	2.02
116	Short qt syndrome 2	Enrichment	KCNQ1	2.02
117	Immune dysregulation with autoimmunity, immunodeficiency, and lymphoproliferation	Enrichment	KCNH2	2.02
118	Maturity-onset diabetes of the young	Enrichment	ABCC8, KCNJ11	2.00
119	Left ventricular noncompaction	Enrichment	HCN4	1.99
120	Jervell and lange-nielsen syndrome 1	Enrichment	KCNQ1	1.90
121	Epilepsy, progressive myoclonic, 4, with or without renal failure	Enrichment	KCNH8	1.90
122	Developmental and epileptic encephalopathy 12	Enrichment	KCNH5	1.90
123	Cardiomyopathy, familial hypertrophic, 26	Enrichment	KCNH2	1.90
124	Atrial fibrillation	Enrichment	KCNQ1	1.90
125	Pregnancy loss, recurrent 1	Enrichment	KCNQ1	1.90
126	Cardiomyopathy, dilated, 1o	Enrichment	ABCC9	1.82
127	Diabetes mellitus, permanent neonatal, 1	Enrichment	KCNJ11	1.82
128	Birk-barel syndrome	Enrichment	KCNK9	1.82
129	Keppen-lubinsky syndrome	Enrichment	KCNJ6	1.82
130	Hypoglycemia, leucine-induced	Enrichment	ABCC8	1.82
131	Night blindness, congenital stationary, type 1h	Enrichment	GNB3	1.82
132	Atrial fibrillation, familial, 12	Enrichment	ABCC9	1.82
133	Diabetes mellitus, transient neonatal, 2	Enrichment	ABCC8	1.82
134	Facial dysmorphism, hypertrichosis, epilepsy, intellectual/developmental delay, and gingival overgrowth syndrome	Enrichment	KCNK4	1.82
135	Diabetes mellitus, permanent neonatal, 3	Enrichment	ABCC8	1.82
136	Lodder-merla syndrome, type 1, with impaired intellectual development and cardiac arrhythmia	Enrichment	GNB5	1.82
137	Hyperinsulinism	Enrichment	KCNJ11	1.82
138	Cerebral visual impairment	Enrichment	GNB1	1.82
139	Farsightedness	Enrichment	KCNA6	1.80
140	Early myoclonic encephalopathy	Enrichment	KCND2	1.72
141	Cystic fibrosis	Enrichment	KCNN4	1.68
142	Silver-russell syndrome 1	Enrichment	KCNQ1	1.66
143	Brugada syndrome 1	Enrichment	KCNH2	1.66
144	Third-degree atrioventricular block	Enrichment	KCNA5	1.66
145	Hyperinsulinemic hypoglycemia	Enrichment	ABCC8	1.65
146	Gingival overgrowth	Enrichment	KCNK4	1.65
147	Rare genetic deafness	Enrichment	KCNQ1, KCNQ4	1.59
148	Developmental and epileptic encephalopathy 14	Enrichment	KCNQ2	1.55
149	Spastic paraplegia 17, autosomal dominant	Enrichment	GNG3	1.52
150	Dermatitis, atopic	Enrichment	KCNJ11	1.52
151	Lipodystrophy, congenital generalized, type 2	Enrichment	GNG3	1.52
152	Tobacco addiction	Enrichment	GABBR2	1.52
153	Newborn respiratory distress syndrome	Enrichment	ABCC8	1.52
154	Epilepsy, myoclonic juvenile	Enrichment	KCNQ3	1.46
155	Deafness, autosomal recessive 4, with enlarged vestibular aqueduct	Enrichment	KCNJ10	1.43
156	Spastic diplegia	Enrichment	KCNJ10	1.43
157	Polyhydramnios	Enrichment	ABCC8	1.43
158	Type 2 diabetes mellitus	Enrichment	ABCC8, KCNJ11	1.39
159	Chromosome 1p36 deletion syndrome	Enrichment	KCNAB2	1.39
160	Cone-rod dystrophy 6	Enrichment	KCNV2	1.36
161	Pendred syndrome	Enrichment	KCNJ10	1.35
162	Kleefstra syndrome 1	Enrichment	ABCC9	1.35
163	Patent ductus arteriosus	Enrichment	ABCC9	1.35
164	Hypertrichosis	Enrichment	KCNJ11	1.35
165	Congenital nervous system abnormality	Enrichment	GNB5, KCNJ10, KCNV2	1.33
166	Nervous system disease	Enrichment	GNB5, KCNJ10, KCNV2	1.33
167	Rett syndrome	Enrichment	GABBR2	1.28
168	Bartter disease	Enrichment	KCNJ1	1.28
169	Beckwith-wiedemann syndrome	Enrichment	KCNQ1	1.26
170	Early infantile developmental and epileptic encephalopathy	Enrichment	KCNA1	1.26
171	Gastroesophageal reflux	Enrichment	ABCC8	1.23
172	Fanconi anemia, complementation group c	Enrichment	ABCC9	1.23
173	Rett syndrome, congenital variant	Enrichment	GABBR2	1.23
174	Hypothyroidism	Enrichment	GNB1	1.23
175	Neurofibromatosis, type i	Enrichment	GABBR1	1.18
176	Autism spectrum disorder	Enrichment	KCNMA1	1.15
177	Ear malformation	Enrichment	KCNQ1	1.13
178	Cone dystrophy	Enrichment	KCNV2	1.13
179	Leukemia, acute lymphoblastic	Enrichment	GNB1	1.09
180	Myelodysplastic syndrome	Enrichment	GNB1	1.09
181	Atrial heart septal defect	Enrichment	ABCC8	1.09
182	Diabetes mellitus	Enrichment	KCNJ11	1.09
183	Heritable pulmonary arterial hypertension	Enrichment	KCNK3	1.09
184	Interatrial communication	Enrichment	ABCC8	1.09
185	Stargardt disease 1	Enrichment	KCNV2	1.04
186	Pulmonary hypertension, primary, 1	Enrichment	KCNK3	1.03
187	Familial hypertrophic cardiomyopathy	Enrichment	KCNH2	1.00
188	Non-syndromic genetic deafness	Enrichment	KCNQ4	0.97
189	Hypertension, essential	Enrichment	GNB3	0.92
190	Cleft palate, isolated	Enrichment	GNB1	0.92
191	Benign epilepsy with centrotemporal spikes	Enrichment	KCNQ3	0.91
192	Nonsyndromic hearing loss	Enrichment	KCNQ4	0.90
193	Centralopathic epilepsy	Enrichment	KCNQ3	0.89
194	Body mass index quantitative trait locus 11	Enrichment	KCNH2	0.83
195	Rare autosomal dominant non-syndromic sensorineural deafness type dfna	Enrichment	KCNQ4	0.82
196	Attention deficit-hyperactivity disorder	Enrichment	GNB5	0.81
197	Congenital stationary night blindness	Enrichment	GNB3	0.79
198	Strabismus	Enrichment	GNB1	0.73
199	Cone-rod dystrophy 2	Enrichment	KCNV2	0.71
200	Dystonia	Enrichment	GNB1	0.63
201	Microcephaly	Enrichment	GNB1, KCNJ10	0.62
202	Colorectal cancer	Enrichment	KCNB2	0.62
203	Complex neurodevelopmental disorder	Enrichment	GNB2, KCNA2	0.62
204	Cerebral palsy	Enrichment	GNB1	0.59
205	Familial isolated dilated cardiomyopathy	Enrichment	ABCC9	0.48
206	Breast cancer	Enrichment	GNG3	0.36
207	Hereditary retinal dystrophy	Enrichment	KCNV2	0.22
208	Fundus dystrophy	Enrichment	KCNV2	0.22

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Potassium Channels

Pathway Network for Potassium Channels

Pathway network for the Potassium Channels SuperPath

Member Pathways for Potassium Channels

Pathways in the Potassium Channels SuperPath

Gene overlap in member pathways for Potassium Channels SuperPath

Associated Genes for Potassium Channels

Associated Disorders for Potassium Channels

Disorders associated with Potassium Channels SuperPath

STRING Interaction Network for Potassium Channels

Sources for Potassium Channels