Pre-implantation embryo

No Pathway Network information available for Pre-implantation embryo

Pathways in the Pre-implantation embryo SuperPath

#	Name	Source	Genes
1	Pre-implantation embryo	WikiPathways	AQP3 AQP9 ARGFX ATP1A1 BARX2 BATF3 CDH1 CDX2 CELF3 DDIT3 DLX2 DNMT3L DPPA3 DPRX E2F5 EGR1 ELAVL1 ESRRA FOSB FOXD1 FOXQ1 GATA2 GATA3 HMGA1 HNRNPAB IRF4 IRX5 KHSRP KLF4 LEUTX MACROH2A2 MOS MTA3 MXD1 MYBL1 NANOG NANOGNB NKX2-1 NLRP5 NR3C2 PADI6 PBX1 POU5F1 SIX3 SMARCA4 SOX11 SOX2 SOX8 TBX3 TCF7L1 TEAD4 TFAP2B TPRX1 ZAR1 ZFP36 ZFP36L2 ZFP42 ZSCAN4 (see all 58) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	CDH1	Cadherin 1	Protein Coding	1
2	FOXQ1	Forkhead Box Q1	Protein Coding	1
3	KLF4	KLF Transcription Factor 4	Protein Coding	1
4	KHSRP	KH-Type Splicing Regulatory Protein	Protein Coding	1
5	TCF7L1	Transcription Factor 7 Like 1	Protein Coding	1
6	NANOG	Nanog Homeobox	Protein Coding	1
7	ZFP36	ZFP36 Ring Finger Protein	Protein Coding	1
8	NKX2-1	NK2 Homeobox 1	Protein Coding	1
9	TFAP2B	Transcription Factor AP-2 Beta	Protein Coding	1
10	TBX3	T-Box Transcription Factor 3	Protein Coding	1
11	ZFP36L2	ZFP36 Ring Finger Protein Like 2	Protein Coding	1
12	SOX11	SRY-Box Transcription Factor 11	Protein Coding	1
13	SOX2	SRY-Box Transcription Factor 2	Protein Coding	1
14	SMARCA4	SWI/SNF Related BAF Chromatin Remodeling Complex Subunit ATPase 4	Protein Coding	1
15	SIX3	SIX Homeobox 3	Protein Coding	1
16	BATF3	Basic Leucine Zipper ATF-Like Transcription Factor 3	Protein Coding	1
17	POU5F1	POU Class 5 Homeobox 1	Protein Coding	1
18	PBX1	PBX Homeobox 1	Protein Coding	1
19	ATP1A1	ATPase Na+/K+ Transporting Subunit Alpha 1	Protein Coding	1
20	MYBL1	MYB Proto-Oncogene Like 1	Protein Coding	1
21	NR3C2	Nuclear Receptor Subfamily 3 Group C Member 2	Protein Coding	1
22	MXD1	MAX Dimerization Protein 1	Protein Coding	1
23	IRF4	Interferon Regulatory Factor 4	Protein Coding	1
24	AQP9	Aquaporin 9	Protein Coding	1
25	AQP3	Aquaporin 3 (Gill Blood Group)	Protein Coding	1
26	DPPA3	Developmental Pluripotency Associated 3	Protein Coding	1
27	PADI6	Peptidyl Arginine Deiminase 6	Protein Coding	1
28	HNRNPAB	Heterogeneous Nuclear Ribonucleoprotein A/B	Protein Coding	1
29	HMGA1	High Mobility Group AT-Hook 1	Protein Coding	1
30	SOX8	SRY-Box Transcription Factor 8	Protein Coding	1
31	GATA3	GATA Binding Protein 3	Protein Coding	1
32	GATA2	GATA Binding Protein 2~Name Same As:- HGNC:18350	Protein Coding	1
33	FOSB	FosB Proto-Oncogene, AP-1 Transcription Factor Subunit	Protein Coding	1
34	ESRRA	Estrogen Related Receptor Alpha	Protein Coding	1
35	ELAVL1	ELAV Like RNA Binding Protein 1	Protein Coding	1
36	EGR1	Early Growth Response 1	Protein Coding	1
37	E2F5	E2F Transcription Factor 5	Protein Coding	1
38	DLX2	Distal-Less Homeobox 2	Protein Coding	1
39	DDIT3	DNA Damage Inducible Transcript 3	Protein Coding	1
40	CDX2	Caudal Type Homeobox 2	Protein Coding	1
41	IRX5	Iroquois Homeobox 5	Protein Coding	1
42	BARX2	BARX Homeobox 2	Protein Coding	1
43	ZFP42	ZFP42 Zinc Finger Protein	Protein Coding	1
44	NLRP5	NLR Family Pyrin Domain Containing 5	Protein Coding	1
45	CELF3	CUGBP Elav-Like Family Member 3	Protein Coding	1
46	TEAD4	TEA Domain Transcription Factor 4	Protein Coding	1
47	MTA3	Metastasis Associated 1 Family Member 3	Protein Coding	1
48	MACROH2A2	MacroH2A.2 Histone	Protein Coding	1
49	DPRX	Divergent-Paired Related Homeobox	Protein Coding	1
50	ARGFX	Arginine-Fifty Homeobox	Protein Coding	1
51	MOS	MOS Proto-Oncogene, Serine/Threonine Kinase	Protein Coding	1
52	NANOGNB	NANOG Neighbor Homeobox	Protein Coding	1
53	LEUTX	Leucine Twenty Homeobox	Protein Coding	1
54	ZAR1	Zygote Arrest 1	Protein Coding	1
55	DNMT3L	DNA Methyltransferase 3 Like	Protein Coding	1
56	TPRX1	Tetrapeptide Repeat Homeobox 1	Protein Coding	1
57	FOXD1	Forkhead Box D1	Protein Coding	1
58	ZSCAN4	Zinc Finger And SCAN Domain Containing 4	Protein Coding	1

Disorders associated with Pre-implantation embryo SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Histiocytoid hemangioma	Enrichment	FOSB, ZFP36L2	3.75
2	Coffin-siris syndrome 1	Enrichment	SMARCA4, SOX11	2.74
3	Craniosynostosis	Enrichment	SOX11, TFAP2B	2.49
4	Skin/hair/eye pigmentation, variation in, 8	Enrichment	IRF4	2.37
5	Char syndrome	Enrichment	TFAP2B	2.37
6	Oocyte/zygote/embryo maturation arrest 13	Enrichment	ZFP36L2	2.37
7	Immunodeficiency 131	Enrichment	IRF4	2.37
8	Congenital anomalies of kidney and urinary tract syndrome with or without hearing loss, abnormal ears, or developmental delay	Enrichment	PBX1	2.37
9	Oocyte/zygote/embryo maturation arrest 20	Enrichment	MOS	2.37
10	Lymphedema, primary, with myelodysplasia	Enrichment	GATA2	2.37
11	Hypertension, early-onset, autosomal dominant, with severe exacerbation in pregnancy	Enrichment	NR3C2	2.37
12	Immunodeficiency 21	Enrichment	GATA2	2.37
13	Smarca4-deficient sarcoma of thorax	Enrichment	SMARCA4	2.37
14	Ovarian small cell carcinoma	Enrichment	SMARCA4	2.37
15	Patent ductus arteriosus 2	Enrichment	TFAP2B	2.37
16	Intellectual developmental disorder with microcephaly and with or without ocular malformations or hypogonadotropic hypogonadism	Enrichment	SOX11	2.37
17	Deafness-lymphedema-leukemia syndrome	Enrichment	GATA2	2.37
18	Sirenomelia	Enrichment	CDX2	2.37
19	Pseudohyperaldosteronism type 2	Enrichment	NR3C2	2.37
20	Breast lobular carcinoma	Enrichment	CDH1	2.37
21	Female infertility due to an implantation defect of genetic origin	Enrichment	ZFP36L2	2.37
22	Whipple disease	Enrichment	IRF4	2.37
23	Anorectal malformation	Enrichment	CDX2	2.37
24	Blepharocheilodontic syndrome 1	Enrichment	CDH1	2.07
25	Hypoparathyroidism, sensorineural deafness, and renal dysplasia syndrome	Enrichment	GATA3	2.07
26	Holoprosencephaly 2	Enrichment	SIX3	2.07
27	Ulnar-mammary syndrome	Enrichment	TBX3	2.07
28	Rhabdoid tumor predisposition syndrome 2	Enrichment	SMARCA4	2.07
29	Pseudohypoaldosteronism, type i, autosomal dominant	Enrichment	NR3C2	2.07
30	Hamamy syndrome	Enrichment	IRX5	2.07
31	Solitary median maxillary central incisor	Enrichment	SIX3	2.07
32	Charcot-marie-tooth disease, axonal, type 2dd	Enrichment	ATP1A1	2.07
33	Oocyte/zygote/embryo maturation arrest 19	Enrichment	NLRP5	2.07
34	Rhabdoid tumor predisposition syndrome	Enrichment	SMARCA4	2.07
35	Hypomagnesemia, seizures, and impaired intellectual development 2	Enrichment	ATP1A1	2.07
36	Choreoathetosis and congenital hypothyroidism with or without pulmonary dysfunction	Enrichment	NKX2-1	2.07
37	Otosclerosis 12	Enrichment	SMARCA4	2.07
38	Coffin-siris syndrome 4	Enrichment	SMARCA4	2.07
39	B-lymphoblastic leukemia/lymphoma with hyperdiploidy	Enrichment	GATA3	2.07
40	Hypoparathyroidism-deafness-renal disease syndrome	Enrichment	GATA3	2.07
41	B-lymphoblastic leukemia/lymphoma with t(1;19)(q23;p13.3)	Enrichment	PBX1	2.07
42	Autosomal dominant nonsyndromic deafness	Enrichment	GATA3	2.07
43	Craniofacial dysplasia - osteopenia syndrome	Enrichment	IRX5	2.07
44	Renal hypoplasia, bilateral	Enrichment	PBX1	2.07
45	Familial patent arterial duct	Enrichment	TFAP2B	2.07
46	Pseudohypoaldosteronism	Enrichment	NR3C2	2.07
47	Nkx2-1-related disorders	Enrichment	NKX2-1	2.07
48	Oocyte/zygote/embryo maturation arrest 16	Enrichment	PADI6	1.89
49	Myxoid liposarcoma	Enrichment	DDIT3	1.89
50	End stage renal disease	Enrichment	GATA3	1.89
51	Adenoid cystic carcinoma	Enrichment	MYBL1	1.89
52	Chorea, benign hereditary	Enrichment	NKX2-1	1.77
53	Diffuse gastric and lobular breast cancer syndrome	Enrichment	CDH1	1.77
54	Microphthalmia, syndromic 3	Enrichment	SOX2	1.77
55	Schizencephaly	Enrichment	SIX3	1.77
56	Thyroid cancer, nonmedullary, 1	Enrichment	NKX2-1	1.77
57	Hereditary ataxia	Enrichment	NKX2-1	1.77
58	Pseudomyogenic hemangioendothelioma	Enrichment	FOSB	1.77
59	Intestinal pseudo-obstruction	Enrichment	TFAP2B	1.60
60	Cleft lip with or without cleft palate	Enrichment	CDH1	1.60
61	Hypothyroidism, congenital, nongoitrous, 2	Enrichment	NKX2-1	1.53
62	Neuroblastoma	Enrichment	SMARCA4	1.47
63	Choreatic disease	Enrichment	NKX2-1	1.47
64	Hypogonadotropic hypogonadism	Enrichment	SOX11	1.42
65	Ventricular septal defect	Enrichment	SMARCA4	1.42
66	Myelodysplastic syndrome	Enrichment	GATA2	1.34
67	Nanophthalmos	Enrichment	SOX2	1.34
68	Atrial heart septal defect	Enrichment	SMARCA4	1.34
69	Interatrial communication	Enrichment	SMARCA4	1.34
70	Septooptic dysplasia	Enrichment	SOX2	1.30
71	Hypercholesterolemia, familial, 1	Enrichment	SMARCA4	1.27
72	Hypogonadotropic hypogonadism 7 with or without anosmia	Enrichment	SOX11	1.23
73	Cleft lip/palate	Enrichment	CDH1	1.23
74	Familial hypercholesterolemia	Enrichment	SMARCA4	1.21
75	Septopreoptic holoprosencephaly	Enrichment	SIX3	1.21
76	Midline interhemispheric variant of holoprosencephaly	Enrichment	SIX3	1.21
77	Microform holoprosencephaly	Enrichment	SIX3	1.18
78	Lobar holoprosencephaly	Enrichment	SIX3	1.18
79	Cleft palate, isolated	Enrichment	SMARCA4	1.15
80	Alobar holoprosencephaly	Enrichment	SIX3	1.15
81	Semilobar holoprosencephaly	Enrichment	SIX3	1.13
82	Autism spectrum disorder	Enrichment	NR3C2, PBX1	1.10
83	Macs syndrome	Enrichment	SOX2	1.09
84	Endometrial cancer	Enrichment	CDH1	1.06
85	Microphthalmia	Enrichment	SOX2	1.05
86	Inherited cancer-predisposing syndrome	Enrichment	CDH1, SMARCA4	0.96
87	Prostate cancer	Enrichment	CDH1	0.93
88	Differentiated thyroid carcinoma	Enrichment	NKX2-1	0.93
89	Cakut	Enrichment	GATA3	0.87
90	Cerebral palsy	Enrichment	SMARCA4	0.81
91	Leukemia, acute myeloid	Enrichment	GATA2	0.80
92	Type 2 diabetes mellitus	Enrichment	HMGA1	0.78
93	Gastric cancer	Enrichment	CDH1	0.77
94	Hereditary breast carcinoma	Enrichment	CDH1	0.76
95	Myeloma, multiple	Enrichment	NKX2-1	0.67
96	Breast cancer	Enrichment	CDH1	0.56
97	Colorectal cancer	Enrichment	CDH1	0.51
98	Ovarian cancer	Enrichment	CDH1	0.45

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Pre-implantation embryo

Pathway Network for Pre-implantation embryo

Member Pathways for Pre-implantation embryo

Pathways in the Pre-implantation embryo SuperPath

Associated Genes for Pre-implantation embryo

Associated Disorders for Pre-implantation embryo

Disorders associated with Pre-implantation embryo SuperPath

STRING Interaction Network for Pre-implantation embryo

Sources for Pre-implantation embryo