Primary focal segmental glomerulosclerosis (FSGS)

No Pathway Network information available for Primary focal segmental glomerulosclerosis (FSGS)

Pathways in the Primary focal segmental glomerulosclerosis (FSGS) SuperPath

#	Name	Source	Genes
1	Primary focal segmental glomerulosclerosis (FSGS)	WikiPathways	ACTN4 AGRN AKT1 CAMK2B CD151 CD2AP CD80 CDH2 CDKN1A CDKN1B CDKN1C CLDN1 COL4A3 COL4A4 COL4A5 CR1 CTNNB1 CTSL DAG1 DKK1 DNM1 FAT1 FYN ILK INF2 IRF6 ITGA3 ITGAV ITGB1 ITGB3 ITGB4 JAG1 KIRREL2 KIRREL3 KRT8 LAMA5 LAMB2 LIMS1 LMX1B LRP5 LRP6 MKI67 MME MYH9 MYO1E NCK1 NOTCH1 NPHS1 NPHS2 PARVA PAX2 PCNA PLAUR PLCE1 PLCG1 PODXL PTK2 PTPRO SCARB2 SMARCAL1 SYNPO TGFB1 TLN1 TLR4 TRPC6 UTRN VCL VIM VTN WNT1 WT1 YWHAQ (see all 72) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	CD151	CD151 Molecule (Raph Blood Group)	Protein Coding	1
2	SCARB2	Scavenger Receptor Class B Member 2	Protein Coding	1
3	CD80	CD80 Molecule	Protein Coding	1
4	CLDN1	Claudin 1	Protein Coding	1
5	CAMK2B	Calcium/Calmodulin Dependent Protein Kinase II Beta	Protein Coding	1
6	ACTN4	Actinin Alpha 4	Protein Coding	1
7	NPHS2	NPHS2 Stomatin Family Member, Podocin	Protein Coding	1
8	WT1	WT1 Transcription Factor	Protein Coding	1
9	WNT1	Wnt Family Member 1	Protein Coding	1
10	VTN	Vitronectin	Protein Coding	1
11	VIM	Vimentin	Protein Coding	1
12	VCL	Vinculin	Protein Coding	1
13	TRPC6	Transient Receptor Potential Cation Channel Subfamily C Member 6	Protein Coding	1
14	TLR4	Toll Like Receptor 4	Protein Coding	1
15	TLN1	Talin 1	Protein Coding	1
16	TGFB1	Transforming Growth Factor Beta 1	Protein Coding	1
17	INF2	Inverted Formin 2	Protein Coding	1
18	PTPRO	Protein Tyrosine Phosphatase Receptor Type O	Protein Coding	1
19	PTK2	Protein Tyrosine Kinase 2	Protein Coding	1
20	PARVA	Parvin Alpha	Protein Coding	1
21	PODXL	Podocalyxin Like	Protein Coding	1
22	PLCG1	Phospholipase C Gamma 1	Protein Coding	1
23	PLAUR	Plasminogen Activator, Urokinase Receptor	Protein Coding	1
24	PLCE1	Phospholipase C Epsilon 1	Protein Coding	1
25	PCNA	Proliferating Cell Nuclear Antigen	Protein Coding	1
26	PAX2	Paired Box 2	Protein Coding	1
27	SMARCAL1	SNF2 Related Chromatin Remodeling Annealing Helicase 1	Protein Coding	1
28	NPHS1	NPHS1 Adhesion Molecule, Nephrin	Protein Coding	1
29	NOTCH1	Notch Receptor 1	Protein Coding	1
30	NCK1	NCK Adaptor Protein 1	Protein Coding	1
31	MYO1E	Myosin IE	Protein Coding	1
32	MYH9	Myosin Heavy Chain 9	Protein Coding	1
33	MME	Membrane Metalloendopeptidase	Protein Coding	1
34	MKI67	Marker Of Proliferation Ki-67	Protein Coding	1
35	LRP5	LDL Receptor Related Protein 5	Protein Coding	1
36	LRP6	LDL Receptor Related Protein 6	Protein Coding	1
37	LMX1B	LIM Homeobox Transcription Factor 1 Beta	Protein Coding	1
38	LAMB2	Laminin Subunit Beta 2	Protein Coding	1
39	KRT8	Keratin 8	Protein Coding	1
40	AGRN	Agrin	Protein Coding	1
41	ITGB4	Integrin Subunit Beta 4	Protein Coding	1
42	ITGB3	Integrin Subunit Beta 3	Protein Coding	1
43	ITGB1	Integrin Subunit Beta 1	Protein Coding	1
44	ITGAV	Integrin Subunit Alpha V	Protein Coding	1
45	ITGA3	Integrin Subunit Alpha 3	Protein Coding	1
46	IRF6	Interferon Regulatory Factor 6	Protein Coding	1
47	ILK	Integrin Linked Kinase	Protein Coding	1
48	FYN	FYN Proto-Oncogene, Src Family Tyrosine Kinase	Protein Coding	1
49	CD2AP	CD2 Associated Protein	Protein Coding	1
50	DKK1	Dickkopf Wnt Signaling Pathway Inhibitor 1	Protein Coding	1
51	FAT1	FAT Atypical Cadherin 1	Protein Coding	1
52	AKT1	AKT Serine/Threonine Kinase 1	Protein Coding	1
53	JAG1	Jagged Canonical Notch Ligand 1	Protein Coding	1
54	DNM1	Dynamin 1	Protein Coding	1
55	DAG1	Dystroglycan 1	Protein Coding	1
56	CTSL	Cathepsin L	Protein Coding	1
57	CTNNB1	Catenin Beta 1	Protein Coding	1
58	CR1	Complement C3b/C4b Receptor 1 (Knops Blood Group)	Protein Coding	1
59	COL4A5	Collagen Type IV Alpha 5 Chain	Protein Coding	1
60	COL4A4	Collagen Type IV Alpha 4 Chain	Protein Coding	1
61	COL4A3	Collagen Type IV Alpha 3 Chain	Protein Coding	1
62	YWHAQ	Tyrosine 3-Monooxygenase/Tryptophan 5-Monooxygenase Activation Protein Theta	Protein Coding	1
63	CDKN1C	Cyclin Dependent Kinase Inhibitor 1C	Protein Coding	1
64	CDKN1B	Cyclin Dependent Kinase Inhibitor 1B	Protein Coding	1
65	CDKN1A	Cyclin Dependent Kinase Inhibitor 1A	Protein Coding	1
66	CDH2	Cadherin 2	Protein Coding	1
67	KIRREL3	Kirre Like Nephrin Family Adhesion Molecule 3	Protein Coding	1
68	KIRREL2	Kirre Like Nephrin Family Adhesion Molecule 2	Protein Coding	1
69	SYNPO	Synaptopodin	Protein Coding	1
70	UTRN	Utrophin	Protein Coding	1
71	LIMS1	LIM Zinc Finger Domain Containing 1	Protein Coding	1
72	LAMA5	Laminin Subunit Alpha 5	Protein Coding	1

Disorders associated with Primary focal segmental glomerulosclerosis (FSGS) SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Genetic steroid-resistant nephrotic syndrome	Enrichment	ACTN4, CD2AP, COL4A3, INF2, LAMA5, MYO1E, NPHS1, NPHS2, PAX2, PLCE1, PTPRO, TRPC6, WT1	10.68
2	Nephrotic syndrome	Enrichment	COL4A3, COL4A4, COL4A5, FAT1, INF2, ITGA3, KIRREL2, LAMA5, LAMB2, LMX1B, MYO1E, NPHS1, NPHS2, PAX2, PLCE1, SMARCAL1, SYNPO, TRPC6	10.59
3	Focal segmental glomerulosclerosis	Enrichment	COL4A4, COL4A5, INF2, NPHS1, NPHS2, PAX2, PLCE1, SMARCAL1, TRPC6, WT1	10.52
4	Kidney disease	Enrichment	COL4A3, COL4A4, COL4A5, INF2, LAMB2, NPHS1, WT1	10.43
5	Nephrotic syndrome, type 1	Enrichment	FAT1, KIRREL2, NPHS1, NPHS2, PLCE1	9.31
6	Digenic alport syndrome	Enrichment	COL4A3, COL4A4, COL4A5	6.84
7	Hypertension	Enrichment	COL4A4, COL4A5, INF2, MYH9	5.90
8	Alport syndrome 3a, autosomal dominant	Enrichment	COL4A3, COL4A4, COL4A5	5.85
9	Autosomal dominant alport syndrome	Enrichment	COL4A3, COL4A4, COL4A5	5.85
10	Alport syndrome	Enrichment	COL4A3, COL4A4, COL4A5	5.85
11	Chronic kidney disease	Enrichment	COL4A4, COL4A5, NPHS2	4.40
12	Hematuria, benign familial, 1	Enrichment	COL4A3, COL4A4	4.08
13	Osteoporosis, juvenile	Enrichment	DKK1, WNT1	4.08
14	Polycystic liver disease	Enrichment	CTNNB1, LRP5, LRP6	4.03
15	Autosomal dominant polycystic liver disease	Enrichment	CTNNB1, LRP5, LRP6	4.03
16	Alport syndrome 2, autosomal recessive	Enrichment	COL4A3, COL4A4	3.78
17	Autosomal recessive alport syndrome	Enrichment	COL4A3, COL4A4	3.78
18	Exudative vitreoretinopathy 1	Enrichment	CTNNB1, LRP5	3.56
19	Multiple endocrine neoplasia, type i	Enrichment	CDKN1A, CDKN1B	3.24
20	Exudative vitreoretinopathy	Enrichment	CTNNB1, LRP5	3.12
21	Presynaptic congenital myasthenic syndromes	Enrichment	AGRN, LAMA5	2.83
22	Ovarian cancer	Enrichment	AKT1, CDKN1B, CTNNB1, WT1	2.69
23	Multiple sclerosis	Enrichment	ITGB4, LAMA5	2.62
24	Osteoporosis	Enrichment	LRP5, WNT1	2.62
25	Atypical hemolytic-uremic syndrome	Enrichment	COL4A5, SMARCAL1	2.55
26	Chiari malformation type i	Enrichment	DKK1	2.28
27	Proteus syndrome	Enrichment	AKT1	2.28
28	Endosteal hyperostosis, autosomal dominant	Enrichment	LRP5	2.28
29	Focal segmental glomerulosclerosis 10	Enrichment	LMX1B	2.28
30	Alport syndrome 1, x-linked	Enrichment	COL4A5	2.28
31	Bone mineral density quantitative trait locus 1	Enrichment	LRP5	2.28
32	Exudative vitreoretinopathy 4	Enrichment	LRP5	2.28
33	Focal segmental glomerulosclerosis 1	Enrichment	ACTN4	2.28
34	Deafness, autosomal dominant 17	Enrichment	MYH9	2.28
35	Orofacial cleft 6	Enrichment	IRF6	2.28
36	Raph blood group system	Enrichment	CD151	2.28
37	Popliteal pterygium syndrome	Enrichment	IRF6	2.28
38	Nail-patella syndrome	Enrichment	LMX1B	2.28
39	Focal segmental glomerulosclerosis 2	Enrichment	TRPC6	2.28
40	Charcot-marie-tooth disease, dominant intermediate e	Enrichment	INF2	2.28
41	Muscular dystrophy-dystroglycanopathy , type a, 9	Enrichment	DAG1	2.28
42	Schimke immunoosseous dysplasia	Enrichment	SMARCAL1	2.28
43	Tooth agenesis, selective, 7	Enrichment	LRP6	2.28
44	Spinocerebellar ataxia 43	Enrichment	MME	2.28
45	Exudative vitreoretinopathy 8	Enrichment	LRP6	2.28
46	Charcot-marie-tooth disease, axonal, type 2hh	Enrichment	JAG1	2.28
47	Nephrotic syndrome, type 26	Enrichment	LAMA5	2.28
48	Intellectual developmental disorder, autosomal dominant 54	Enrichment	CAMK2B	2.28
49	Immune dysregulation, autoimmunity, and autoinflammation	Enrichment	PLCG1	2.28
50	Agenesis of corpus callosum, cardiac, ocular, and genital syndrome	Enrichment	CDH2	2.28
51	Osteoporosis-pseudoglioma syndrome	Enrichment	LRP5	2.28
52	Coronary artery disease, autosomal dominant 2	Enrichment	LRP6	2.28
53	Bone mineral density quantitative trait locus 16	Enrichment	WNT1	2.28
54	Cardiomyopathy, dilated, 1w	Enrichment	VCL	2.28
55	Polycystic liver disease 4 with or without kidney cysts	Enrichment	LRP5	2.28
56	Neuroendocrine tumor	Enrichment	CDKN1B	2.28
57	Meacham syndrome	Enrichment	WT1	2.28
58	Epidermolysis bullosa simplex 7, with nephropathy and deafness	Enrichment	CD151	2.28
59	Focal segmental glomerulosclerosis 3	Enrichment	CD2AP	2.28
60	Arrhythmogenic right ventricular dysplasia, familial, 14	Enrichment	CDH2	2.28
61	Cardiomyopathy, familial hypertrophic, 15	Enrichment	VCL	2.28
62	Cowden syndrome 6	Enrichment	AKT1	2.28
63	Nephrotic syndrome, type 6	Enrichment	PTPRO	2.28
64	Ataxia-telangiectasia-like disorder 2	Enrichment	PCNA	2.28
65	Macular degeneration, age-related, 10	Enrichment	TLR4	2.28
66	Focal segmental glomerulosclerosis 5	Enrichment	INF2	2.28
67	Muscular dystrophy-dystroglycanopathy , type c, 9	Enrichment	DAG1	2.28
68	Focal segmental glomerulosclerosis 6	Enrichment	MYO1E	2.28
69	Irf6-related disorders	Enrichment	IRF6	2.28
70	Autosomal dominant popliteal pterygium syndrome	Enrichment	IRF6	2.28
71	Deafness, congenital heart defects, and posterior embryotoxon	Enrichment	JAG1	2.28
72	Lipoid nephrosis	Enrichment	LMX1B	2.28
73	Bent bone dysplasia syndrome 2	Enrichment	LAMA5	2.28
74	Congenital membranous nephropathy due to maternal anti-neutral endopeptidase alloimmunization	Enrichment	MME	2.28
75	Attention deficit-hyperactivity disorder 8	Enrichment	CDH2	2.28
76	Adenoid ameloblastoma	Enrichment	CTNNB1	2.28
77	Lrp5-related primary osteoporosis	Enrichment	LRP5	2.28
78	Charcot-marie-tooth disease type 2t	Enrichment	MME	2.28
79	Mme-related autosomal dominant charcot marie tooth disease type 2	Enrichment	MME	2.28
80	Autosomal dominant nonsyndromic hearing loss 17	Enrichment	MYH9	2.28
81	Immune dysregulation, neurodevelopmental defects, and colitis	Enrichment	ITGAV	2.28
82	Capillary leak syndrome	Enrichment	TLN1	2.28
83	X-linked alport syndrome	Enrichment	COL4A5	2.28
84	Familial nephrotic syndrome	Enrichment	NPHS1	2.28
85	Muscle-eye-brain disease with bilateral multicystic leucodystrophy	Enrichment	DAG1	2.28
86	Pax2-related disorder	Enrichment	PAX2	2.28
87	Osteosclerosis-developmental delay-craniosynostosis syndrome	Enrichment	LRP5	2.28
88	Intrauterine growth restriction-short stature-early adult-onset diabetes syndrome	Enrichment	CDKN1C	2.28
89	Premature aging	Enrichment	VIM	2.28
90	Lama5-related multisystemic syndrome	Enrichment	LAMA5	2.28
91	Microcystic stromal tumor	Enrichment	CTNNB1	2.28
92	Hepatoblastoma	Enrichment	CTNNB1, JAG1	2.26
93	Tooth agenesis	Enrichment	IRF6, LRP6	2.22
94	Brittle bone disorder	Enrichment	LRP5, WNT1	2.18
95	Tetralogy of fallot	Enrichment	JAG1, NOTCH1	2.08
96	Bladder cancer	Enrichment	CDKN1A, CTNNB1	1.99
97	Papillorenal syndrome	Enrichment	PAX2	1.98
98	Camurati-engelmann disease 1	Enrichment	TGFB1	1.98
99	Van buchem disease	Enrichment	LRP5	1.98
100	Denys-drash syndrome	Enrichment	WT1	1.98
101	Myasthenic syndrome, congenital, 5	Enrichment	LAMB2	1.98
102	Osteopathia striata with cranial sclerosis	Enrichment	CTNNB1	1.98
103	Nephrotic syndrome, type 2	Enrichment	NPHS2	1.98
104	Cataract 35	Enrichment	MYH9	1.98
105	Nephrotic syndrome, type 4	Enrichment	WT1	1.98
106	Ichthyosis, leukocyte vacuoles, alopecia, and sclerosing cholangitis	Enrichment	CLDN1	1.98
107	Osteogenesis imperfecta, type xv	Enrichment	WNT1	1.98
108	Intellectual developmental disorder, autosomal dominant 4	Enrichment	KIRREL3	1.98
109	Frasier syndrome	Enrichment	WT1	1.98
110	Intrauterine growth retardation, metaphyseal dysplasia, adrenal hypoplasia congenita, and genital anomalies	Enrichment	CDKN1C	1.98
111	Adams-oliver syndrome 5	Enrichment	NOTCH1	1.98
112	Specific language impairment 5	Enrichment	COL4A4	1.98
113	Pierson syndrome	Enrichment	LAMB2	1.98
114	Myasthenic syndrome, congenital, 12	Enrichment	FAT1	1.98
115	Multiple endocrine neoplasia, type iv	Enrichment	CDKN1B	1.98
116	Epidermolysis bullosa, junctional 5a, intermediate	Enrichment	ITGB4	1.98
117	Inflammatory bowel disease, immunodeficiency, and encephalopathy	Enrichment	TGFB1	1.98
118	Nephrotic syndrome, type 5, with or without ocular abnormalities	Enrichment	LAMB2	1.98
119	Epidermolysis bullosa, junctional 7, with interstitial lung disease and nephrotic syndrome	Enrichment	ITGA3	1.98
120	Childhood hepatocellular carcinoma	Enrichment	CTNNB1	1.98
121	Focal segmental glomerulosclerosis 7	Enrichment	PAX2	1.98
122	Cataract 30	Enrichment	VIM	1.98
123	Camurati-engelmann disease	Enrichment	TGFB1	1.98
124	Glomerulonephritis	Enrichment	COL4A4	1.98
125	Pseudosarcomatous fibromatosis	Enrichment	MYH9	1.98
126	Charcot-marie-tooth disease, axonal, type 2t	Enrichment	MME	1.98
127	9q33.3q34.11 microdeletion syndrome	Enrichment	LMX1B	1.98
128	Juvenile nasopharyngeal angiofibroma	Enrichment	CTNNB1	1.98
129	Localized junctional epidermolysis bullosa, non-herlitz type	Enrichment	ITGB4	1.98
130	Van der woude syndrome	Enrichment	IRF6	1.98
131	Teratoma	Enrichment	CTNNB1	1.98
132	Osteosclerosis	Enrichment	LRP5	1.98
133	Renal hypoplasia, bilateral	Enrichment	PAX2	1.98
134	Genetic nephrotic syndrome	Enrichment	NPHS2	1.98
135	Idiopathic nephrotic syndrome	Enrichment	NPHS2	1.98
136	Desmoplastic small round cell tumor	Enrichment	WT1	1.98
137	X-linked diffuse leiomyomatosis-alport syndrome	Enrichment	COL4A5	1.98
138	Desmoid disease, hereditary	Enrichment	CTNNB1	1.80
139	Hyper-ige syndrome 1, autosomal dominant, with recurrent infections	Enrichment	ITGB3	1.80
140	Macrothrombocytopenia and granulocyte inclusions with or without nephritis or sensorineural hearing loss	Enrichment	MYH9	1.80
141	Van der woude syndrome 1	Enrichment	IRF6	1.80
142	Alagille syndrome 1	Enrichment	JAG1	1.80
143	Mesothelioma, malignant	Enrichment	WT1	1.80
144	Bleeding disorder, platelet-type, 16	Enrichment	ITGB3	1.80
145	Osteopetrosis, autosomal dominant 1	Enrichment	LRP5	1.80
146	Muscular dystrophy, duchenne type	Enrichment	UTRN	1.80
147	Nephrotic syndrome, type 3	Enrichment	PLCE1	1.80
148	Neurodevelopmental disorder with spastic diplegia and visual defects	Enrichment	CTNNB1	1.80
149	Anus, imperforate	Enrichment	CTNNB1	1.80
150	Exudative vitreoretinopathy 7	Enrichment	CTNNB1	1.80
151	Nephrotic syndrome, type 24	Enrichment	NPHS2	1.80
152	Pilarowski-bjornsson syndrome	Enrichment	COL4A3	1.80
153	Developmental and epileptic encephalopathy 31b	Enrichment	DNM1	1.80
154	Alport syndrome 3b, autosomal recessive	Enrichment	COL4A3	1.80
155	Desmoid tumor	Enrichment	CTNNB1	1.80
156	Hematuria, benign familial, 2	Enrichment	COL4A3	1.80
157	Cryptogenic cirrhosis	Enrichment	KRT8	1.80
158	Atypical juvenile parkinsonism	Enrichment	PODXL	1.80
159	Bleeding disorder, platelet-type, 24	Enrichment	ITGB3	1.80
160	Keratoacanthoma	Enrichment	NOTCH1	1.80
161	Aniridia 1	Enrichment	WT1	1.68
162	Gaucher disease, type i	Enrichment	SCARB2	1.68
163	Epilepsy, progressive myoclonic, 4, with or without renal failure	Enrichment	SCARB2	1.68
164	Epidermolysis bullosa simplex 5c, with pyloric atresia	Enrichment	ITGB4	1.68
165	Developmental and epileptic encephalopathy 4	Enrichment	LMX1B	1.68
166	Pilomatrixoma	Enrichment	CTNNB1	1.68
167	Alazami syndrome	Enrichment	CTNNB1	1.68
168	Orofacial cleft	Enrichment	LRP6	1.68
169	Retinopathy of prematurity	Enrichment	LRP5	1.68
170	Craniopharyngioma	Enrichment	CTNNB1	1.68
171	Silver-russell syndrome due to a point mutation	Enrichment	CDKN1C	1.68
172	Primary hyperparathyroidism	Enrichment	CDKN1B	1.68
173	Vitreoretinopathy	Enrichment	LRP5	1.68
174	Orofacial clefting syndrome	Enrichment	LRP6	1.68
175	Middle aortic syndrome	Enrichment	JAG1	1.68
176	Cleft lip and alveolus	Enrichment	IRF6	1.68
177	Epidermolysis bullosa simplex 1c, localized	Enrichment	ITGB4	1.58
178	Parkinson disease 2, autosomal recessive juvenile	Enrichment	PODXL	1.58
179	Atrioventricular septal defect	Enrichment	SMARCAL1	1.58
180	Deafness, autosomal recessive 63	Enrichment	MYH9	1.58
181	Leber congenital amaurosis 10	Enrichment	WT1	1.58
182	Myasthenic syndrome, congenital, 8	Enrichment	AGRN	1.58
183	Developmental and epileptic encephalopathy 31a	Enrichment	DNM1	1.58
184	Glanzmann thrombasthenia 2	Enrichment	ITGB3	1.58
185	Histiocytoid hemangioma	Enrichment	VIM	1.58
186	Parkin type of early-onset parkinson disease	Enrichment	PODXL	1.58
187	Aplasia cutis congenita	Enrichment	ITGB4	1.58
188	Cleft upper lip	Enrichment	IRF6	1.58
189	Thrombocytopenia	Enrichment	ITGB3, MYH9	1.57
190	Microcephaly	Enrichment	CAMK2B, CTNNB1, SMARCAL1	1.56
191	Autosomal dominant non-syndromic intellectual disability	Enrichment	CAMK2B, KIRREL3	1.54
192	Weyers acrofacial dysostosis	Enrichment	CTNNB1	1.50
193	Epidermolysis bullosa, junctional 1a, intermediate	Enrichment	ITGB4	1.50
194	Wilms tumor, aniridia, genitourinary anomalies, and impaired intellectual development syndrome	Enrichment	WT1	1.50
195	Epidermolysis bullosa, junctional 5b, with pyloric atresia	Enrichment	ITGB4	1.50
196	Wilms tumor 5	Enrichment	WT1	1.50
197	Hemangioma, capillary infantile	Enrichment	MYH9	1.50
198	Congenital anomalies of kidney and urinary tract 1	Enrichment	PAX2	1.50
199	Inflammatory bowel disease 25, autosomal recessive	Enrichment	TGFB1	1.50
200	Junctional epidermolysis bullosa non-herlitz type	Enrichment	ITGB4	1.50
201	Renal hypoplasia	Enrichment	PAX2	1.50
202	Adrenocortical carcinoma	Enrichment	CTNNB1	1.50
203	Fetomaternal alloimmune thrombocytopenia 1	Enrichment	ITGB3	1.50
204	Il10-related early-onset inflammatory bowel disease	Enrichment	TGFB1	1.50
205	Breast adenocarcinoma	Enrichment	AKT1	1.50
206	Glanzmann thrombasthenia 1	Enrichment	ITGB3	1.44
207	Adams-oliver syndrome	Enrichment	NOTCH1	1.44
208	Gallbladder cancer	Enrichment	CTNNB1	1.44
209	Epidermolysis bullosa simplex	Enrichment	ITGB4	1.44
210	Lennox-gastaut syndrome	Enrichment	DNM1	1.38
211	Hypoplastic left heart syndrome	Enrichment	NOTCH1	1.38
212	Difference of sex development	Enrichment	WT1	1.38
213	Leukemia, acute lymphoblastic 3	Enrichment	WT1	1.33
214	Adult hepatocellular carcinoma	Enrichment	CTNNB1	1.33
215	Cystic kidney disease	Enrichment	PAX2	1.33
216	Junctional epidermolysis bullosa	Enrichment	ITGB4	1.33
217	Cowden syndrome	Enrichment	AKT1	1.33
218	Cataract 30, multiple types	Enrichment	VIM	1.29
219	Progressive myoclonus epilepsy	Enrichment	SCARB2	1.29
220	Autosomal dominant macrothrombocytopenia	Enrichment	ITGB3	1.29
221	46,xy complete gonadal dysgenesis	Enrichment	WT1	1.25
222	Early-onset parkinson's disease	Enrichment	PODXL	1.21
223	Meningioma	Enrichment	AKT1	1.21
224	Postsynaptic congenital myasthenic syndromes	Enrichment	AGRN	1.21
225	Rare genetic deafness	Enrichment	COL4A5, MYH9	1.18
226	Aortic valve disease 1	Enrichment	NOTCH1	1.17
227	Microphthalmia/coloboma 12	Enrichment	PAX2	1.17
228	Osteogenesis imperfecta, type iv	Enrichment	WNT1	1.17
229	Neural tube defects	Enrichment	ITGB1	1.17
230	Stereotypic movement disorder	Enrichment	DNM1	1.17
231	Medulloblastoma	Enrichment	CTNNB1	1.14
232	Myoclonic epilepsy of unverricht and lundborg	Enrichment	SCARB2	1.14
233	Aortic aneurysm, familial thoracic 1	Enrichment	NOTCH1	1.14
234	Walker-warburg syndrome	Enrichment	DAG1	1.14
235	Congenital myasthenic syndrome	Enrichment	AGRN	1.14
236	Cleft lip/palate	Enrichment	IRF6	1.14
237	Inherited isolated arrhythmogenic cardiomyopathy, dominant-right variant	Enrichment	CDH2	1.14
238	46,xy partial gonadal dysgenesis	Enrichment	WT1	1.14
239	Isolated macular dystrophy	Enrichment	COL4A5	1.14
240	Coloboma of macula	Enrichment	PAX2	1.11
241	Wilms tumor 1	Enrichment	WT1	1.11
242	Corpus callosum, agenesis of	Enrichment	CDH2	1.11
243	Osteogenesis imperfecta, type iii	Enrichment	WNT1	1.11
244	Myopia	Enrichment	COL4A4	1.11
245	Isolated corpus callosum agenesis	Enrichment	CDH2	1.11
246	Intellectual disability-hypoplastic corpus callosum-preauricular tag syndrome	Enrichment	CDH2	1.11
247	Colorectal cancer	Enrichment	AKT1, CTNNB1	1.11
248	Creatine phosphokinase, elevated serum	Enrichment	DAG1	1.09
249	Isolated elevated serum creatine phosphokinase levels	Enrichment	DAG1	1.09
250	Isolated congenital microcephaly	Enrichment	SMARCAL1	1.09
251	Cleft palate, isolated	Enrichment	IRF6	1.06
252	Beckwith-wiedemann syndrome	Enrichment	CDKN1C	1.04
253	Heart, malformation of	Enrichment	JAG1	1.04
254	Polycystic kidney disease	Enrichment	COL4A4	1.04
255	Arteriovenous malformations of the brain	Enrichment	CDH2	1.02
256	Behcet syndrome	Enrichment	TLR4	1.02
257	Neuropathy, hereditary motor and sensory, okinawa type	Enrichment	MME	1.02
258	Williams-beuren syndrome	Enrichment	CDKN1C	1.00
259	Congenital nervous system abnormality	Enrichment	CAMK2B, CTNNB1	0.96
260	Nervous system disease	Enrichment	CAMK2B, CTNNB1	0.96
261	Hepatocellular carcinoma	Enrichment	CTNNB1	0.96
262	Myocardial infarction	Enrichment	ITGB3	0.96
263	Skin disease	Enrichment	ITGB4	0.96
264	Malaria	Enrichment	CR1	0.94
265	Auditory neuropathy	Enrichment	CDH2	0.89
266	Severe covid-19	Enrichment	ITGAV	0.84
267	Inherited cancer-predisposing syndrome	Enrichment	CDKN1B, WT1	0.81
268	Cystic fibrosis	Enrichment	TGFB1	0.80
269	Connective tissue disease	Enrichment	NOTCH1	0.80
270	Peripheral nervous system disease	Enrichment	MME	0.80
271	Neuropathy	Enrichment	MME	0.80
272	Cakut	Enrichment	PAX2	0.78
273	Dystonia	Enrichment	CAMK2B	0.77
274	Benign epilepsy with centrotemporal spikes	Enrichment	SCARB2	0.71
275	Hereditary retinal dystrophy	Enrichment	JAG1, LRP5, PAX2	0.70
276	Fundus dystrophy	Enrichment	JAG1, LRP5, PAX2	0.70
277	Centralopathic epilepsy	Enrichment	SCARB2	0.69
278	West syndrome	Enrichment	DNM1	0.68
279	Familial thoracic aortic aneurysm and aortic dissection	Enrichment	NOTCH1	0.68
280	Hereditary breast carcinoma	Enrichment	AKT1	0.68
281	Body mass index quantitative trait locus 11	Enrichment	MYH9	0.63
282	Rare autosomal dominant non-syndromic sensorineural deafness type dfna	Enrichment	MYH9	0.62
283	Familial isolated dilated cardiomyopathy	Enrichment	VCL	0.61
284	Myeloma, multiple	Enrichment	FAT1	0.59
285	Undetermined early-onset epileptic encephalopathy	Enrichment	DNM1	0.59
286	Primary ovarian insufficiency	Enrichment	WT1	0.57
287	Deafness, autosomal recessive	Enrichment	MYH9	0.54
288	Autosomal recessive nonsyndromic deafness	Enrichment	MYH9	0.54
289	Breast cancer	Enrichment	AKT1	0.48
290	Dilated cardiomyopathy	Enrichment	VCL	0.46
291	Rare autosomal recessive non-syndromic sensorineural deafness type dfnb	Enrichment	MYH9	0.42

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Primary focal segmental glomerulosclerosis (FSGS)

Pathway Network for Primary focal segmental glomerulosclerosis (FSGS)

Member Pathways for Primary focal segmental glomerulosclerosis (FSGS)

Pathways in the Primary focal segmental glomerulosclerosis (FSGS) SuperPath

Associated Genes for Primary focal segmental glomerulosclerosis (FSGS)

Associated Disorders for Primary focal segmental glomerulosclerosis (FSGS)

Disorders associated with Primary focal segmental glomerulosclerosis (FSGS) SuperPath

STRING Interaction Network for Primary focal segmental glomerulosclerosis (FSGS)

Sources for Primary focal segmental glomerulosclerosis (FSGS)