procollagen hydroxylation and glycosylation

No Pathway Network information available for procollagen hydroxylation and glycosylation

#	Name	Source	Genes
1	procollagen hydroxylation and glycosylation	PubChem	COLGALT1 COLGALT2 CUX1 P3H1 P4HA1 P4HB PGGHG PLOD1 PPIB (see all 9) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	COLGALT1	Collagen Beta(1-O)Galactosyltransferase 1	Protein Coding	1
2	PGGHG	Protein-Glucosylgalactosylhydroxylysine Glucosidase	Protein Coding	1
3	COLGALT2	Collagen Beta(1-O)Galactosyltransferase 2	Protein Coding	1
4	P4HA1	Prolyl 4-Hydroxylase Subunit Alpha 1	Protein Coding	1
5	P3H1	Prolyl 3-Hydroxylase 1	Protein Coding	1
6	PLOD1	Procollagen-Lysine,2-Oxoglutarate 5-Dioxygenase 1	Protein Coding	1
7	CUX1	Cut Like Homeobox 1	Protein Coding	1
8	P4HB	Prolyl 4-Hydroxylase Subunit Beta	Protein Coding	1
9	PPIB	Peptidylprolyl Isomerase B	Protein Coding	1

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Brittle bone disorder	Enrichment	P3H1, PGGHG, PPIB	6.45
2	Osteogenesis imperfecta, type ii	Enrichment	P3H1, PPIB	5.09
3	Osteogenesis imperfecta, type iii	Enrichment	P3H1, PPIB	4.39
4	Cole-carpenter syndrome 1	Enrichment	P4HB	3.18
5	Brain small vessel disease 3	Enrichment	COLGALT1	3.18
6	Omphalocele	Enrichment	PLOD1	3.18
7	Osteogenesis imperfecta, type ix	Enrichment	PPIB	2.88
8	Osteogenesis imperfecta, type viii	Enrichment	P3H1	2.88
9	Neurodevelopmental disorder with developmental delay and with or without motor or speech delay	Enrichment	CUX1	2.88
10	Osteogenesis imperfecta, type v	Enrichment	PGGHG	2.88
11	Ehlers-danlos syndrome, kyphoscoliotic type, 1	Enrichment	PLOD1	2.70
12	Umbilical hernia	Enrichment	PLOD1	2.70
13	Plod1-related kyphoscoliotic ehlers-danlos syndrome	Enrichment	PLOD1	2.70
14	Cole-carpenter syndrome	Enrichment	P4HB	2.70
15	Brittle cornea syndrome 1	Enrichment	PLOD1	2.48
16	Familial porencephaly	Enrichment	COLGALT1	2.48
17	Osteogenesis imperfecta, type i	Enrichment	P4HB	2.40
18	Keratoconus	Enrichment	PLOD1	2.40
19	Orthostatic intolerance	Enrichment	PLOD1	2.28
20	Osteogenesis imperfecta, type iv	Enrichment	PPIB	2.07
21	Osteoporosis	Enrichment	PGGHG	2.03
22	Hydrocephalus	Enrichment	PLOD1	2.00
23	Ehlers-danlos syndrome	Enrichment	PLOD1	1.90
24	Familial thoracic aortic aneurysm and aortic dissection	Enrichment	PLOD1	1.54
25	Autosomal dominant non-syndromic intellectual disability	Enrichment	CUX1	1.49

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Pathway Network for procollagen hydroxylation and glycosylation