Prostaglandin 2 biosynthesis and metabolism FM

No Pathway Network information available for Prostaglandin 2 biosynthesis and metabolism FM

#	Name	Source	Genes
1	Prostaglandin 2 biosynthesis and metabolism FM	GeneGo (Thomson Reuters)	AKR1A1 AKR1C3 ALOX12B ALOXE3 CBR1 CBR3 CYP4F12 DHRS4 HPGD HPGDS PRDX1 PRDX2 PRDX3 PRDX4 PRDX5 PTGDS PTGES PTGES2 PTGIS PTGR1 PTGS1 PTGS2 TBXAS1 (see all 23) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	ALOX12B	Arachidonate 12-Lipoxygenase, 12R Type	Protein Coding	1
2	CBR1	Carbonyl Reductase 1	Protein Coding	1
3	CBR3	Carbonyl Reductase 3	Protein Coding	1
4	HPGD	15-Hydroxyprostaglandin Dehydrogenase	Protein Coding	1
5	PRDX1	Peroxiredoxin 1	Protein Coding	1
6	PTGDS	Prostaglandin D2 Synthase	Protein Coding	1
7	PTGIS	Prostaglandin I2 Synthase	Protein Coding	1
8	PTGS1	Prostaglandin-Endoperoxide Synthase 1	Protein Coding	1
9	PTGS2	Prostaglandin-Endoperoxide Synthase 2	Protein Coding	1
10	TBXAS1	Thromboxane A Synthase 1	Protein Coding	1
11	PRDX2	Peroxiredoxin 2	Protein Coding	1
12	AKR1C3	Aldo-Keto Reductase Family 1 Member C3	Protein Coding	1
13	PTGES	Prostaglandin E Synthase	Protein Coding	1
14	AKR1A1	Aldo-Keto Reductase Family 1 Member A1	Protein Coding	1
15	PRDX4	Peroxiredoxin 4	Protein Coding	1
16	DHRS4	Dehydrogenase/Reductase 4	Protein Coding	1
17	PRDX3	Peroxiredoxin 3	Protein Coding	1
18	PTGR1	Prostaglandin Reductase 1	Protein Coding	1
19	PRDX5	Peroxiredoxin 5	Protein Coding	1
20	HPGDS	Hematopoietic Prostaglandin D Synthase	Protein Coding	1
21	ALOXE3	Arachidonate Epidermal Lipoxygenase 3	Protein Coding	1
22	CYP4F12	Cytochrome P450 Family 4 Subfamily F Member 12	Protein Coding	1
23	PTGES2	Prostaglandin E Synthase 2	Protein Coding	1

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Self-improving collodion baby	Enrichment	ALOX12B, ALOXE3	5.08
2	Ichthyosis, congenital, autosomal recessive 2	Enrichment	ALOX12B, ALOXE3	4.56
3	Congenital nonbullous ichthyosiform erythroderma	Enrichment	ALOX12B, ALOXE3	3.91
4	Ichthyosis	Enrichment	ALOX12B, ALOXE3	3.82
5	Autosomal recessive congenital ichthyosis	Enrichment	ALOX12B, ALOXE3	3.55
6	Digital clubbing, isolated congenital	Enrichment	HPGD	2.77
7	Ghosal hematodiaphyseal dysplasia	Enrichment	TBXAS1	2.77
8	Spinocerebellar ataxia, autosomal recessive 32	Enrichment	PRDX3	2.77
9	Corneal dystrophy, punctiform and polychromatic pre-descemet	Enrichment	PRDX3	2.77
10	Bleeding disorder, platelet-type, 14	Enrichment	TBXAS1	2.47
11	Primary hypertrophic osteoarthropathy	Enrichment	HPGD	2.47
12	Ichthyosis, congenital, autosomal recessive 3	Enrichment	ALOXE3	2.29
13	Hypertrophic osteoarthropathy, primary, autosomal recessive, 1	Enrichment	HPGD	2.29
14	Currarino syndrome	Enrichment	HPGD	2.17
15	Autosomal recessive cerebellar ataxia	Enrichment	PRDX3	2.07
16	Leukoencephalopathy, brain calcifications, and cysts	Enrichment	ALOX12B	1.93
17	Methylmalonic aciduria and homocystinuria, cblc type	Enrichment	PRDX1	1.87
18	Hypertension, essential	Enrichment	PTGIS	1.55

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Pathway Network for Prostaglandin 2 biosynthesis and metabolism FM