Prostaglandin signaling

No Pathway Network information available for Prostaglandin signaling

Pathways in the Prostaglandin signaling SuperPath

#	Name	Source	Genes
1	Prostaglandin signaling	WikiPathways	AREG CASP1 CCL2 CCL3 CCR2 CD28 CSF1 CXCL1 CXCL10 CXCL8 CXCL9 IFNA1 IL12A IL17A IL17F IL1A IL1B IL6 IRF7 MMP9 NFKB1 NLRP3 PIK3CG PTGER2 PTGES PYCARD TNF VEGFA (see all 28) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	PTGER2	Prostaglandin E Receptor 2	Protein Coding	1
2	PTGES	Prostaglandin E Synthase	Protein Coding	1
3	CD28	CD28 Molecule	Protein Coding	1
4	CASP1	Caspase 1	Protein Coding	1
5	VEGFA	Vascular Endothelial Growth Factor A	Protein Coding	1
6	CCR2	C-C Motif Chemokine Receptor 2	Protein Coding	1
7	TNF	Tumor Necrosis Factor	Protein Coding	1
8	CCL3	C-C Motif Chemokine Ligand 3	Protein Coding	1
9	CCL2	C-C Motif Chemokine Ligand 2	Protein Coding	1
10	PIK3CG	Phosphatidylinositol-4,5-Bisphosphate 3-Kinase Catalytic Subunit Gamma	Protein Coding	1
11	NFKB1	Nuclear Factor Kappa B Subunit 1	Protein Coding	1
12	MMP9	Matrix Metallopeptidase 9	Protein Coding	1
13	CXCL9	C-X-C Motif Chemokine Ligand 9	Protein Coding	1
14	AREG	Amphiregulin	Protein Coding	1
15	IRF7	Interferon Regulatory Factor 7	Protein Coding	1
16	CXCL10	C-X-C Motif Chemokine Ligand 10	Protein Coding	1
17	IL17A	Interleukin 17A	Protein Coding	1
18	IL12A	Interleukin 12A	Protein Coding	1
19	CXCL8	C-X-C Motif Chemokine Ligand 8	Protein Coding	1
20	IL6	Interleukin 6	Protein Coding	1
21	IL1B	Interleukin 1 Beta	Protein Coding	1
22	IL1A	Interleukin 1 Alpha	Protein Coding	1
23	IFNA1	Interferon Alpha 1	Protein Coding	1
24	CXCL1	C-X-C Motif Chemokine Ligand 1	Protein Coding	1
25	PYCARD	PYD And CARD Domain Containing	Protein Coding	1
26	CSF1	Colony Stimulating Factor 1	Protein Coding	1
27	NLRP3	NLR Family Pyrin Domain Containing 3	Protein Coding	1
28	IL17F	Interleukin 17F	Protein Coding	1

Disorders associated with Prostaglandin signaling SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Human immunodeficiency virus type 1	Enrichment	CCL2, CCL3, CCR2	5.20
2	Arteriovenous malformations of the brain	Enrichment	IL6, NLRP3	3.16
3	Cinca syndrome	Enrichment	NLRP3	2.69
4	Keratoendotheliitis fugax hereditaria	Enrichment	NLRP3	2.69
5	Familial cold autoinflammatory syndrome 1	Enrichment	NLRP3	2.69
6	Polycystic lung disease	Enrichment	CCR2	2.69
7	Immunodeficiency 39 viral infections	Enrichment	IRF7	2.69
8	Candidiasis, familial, 6	Enrichment	IL17F	2.69
9	Muckle-wells syndrome	Enrichment	NLRP3	2.69
10	Deafness, autosomal dominant 34, with or without inflammation	Enrichment	NLRP3	2.69
11	Immunodeficiency 39	Enrichment	IRF7	2.69
12	Microvascular complications of diabetes 1	Enrichment	VEGFA	2.69
13	Immunodeficiency 97 with autoinflammation	Enrichment	PIK3CG	2.69
14	Immunodeficiency 123 with hpv-related verrucosis	Enrichment	CD28	2.69
15	Cryopyrin associated periodic syndrome	Enrichment	NLRP3	2.69
16	Familial amyloid nephropathy with urticaria and deafness	Enrichment	NLRP3	2.69
17	Immunodeficiency, common variable, 12, with autoimmunity	Enrichment	NFKB1	2.38
18	Immunodeficiency 127	Enrichment	TNF	2.38
19	Metaphyseal anadysplasia 2	Enrichment	MMP9	2.38
20	Pericardial effusion	Enrichment	NLRP3	2.38
21	Metaphyseal anadysplasia	Enrichment	MMP9	2.38
22	Common variable immunodeficiency 12	Enrichment	NFKB1	2.38
23	Asthma, nasal polyps, and aspirin intolerance	Enrichment	PTGER2	2.21
24	Mycosis fungoides	Enrichment	CD28	2.21
25	Psoriatic arthritis	Enrichment	TNF	2.21
26	Migraine without aura	Enrichment	TNF	2.21
27	Saczary syndrome	Enrichment	CD28	2.21
28	Kaposi sarcoma	Enrichment	IL6	2.08
29	Cerebral malaria	Enrichment	TNF	2.08
30	Systemic-onset juvenile idiopathic arthritis	Enrichment	IL6	2.08
31	Rheumatoid arthritis, systemic juvenile	Enrichment	IL6	1.99
32	Vascular dementia	Enrichment	TNF	1.99
33	Type 1 diabetes mellitus	Enrichment	IL6	1.91
34	Chronic mucocutaneous candidiasis	Enrichment	IL17F	1.91
35	Common variable immunodeficiency	Enrichment	NFKB1	1.84
36	Inflammatory bowel disease 1	Enrichment	IL6	1.73
37	Primary biliary cholangitis	Enrichment	IL12A	1.73
38	Ciliary dyskinesia, primary, 3	Enrichment	NFKB1	1.69
39	Asthma	Enrichment	TNF	1.65
40	Alzheimer's disease	Enrichment	TNF	1.58
41	Behcet syndrome	Enrichment	IL12A	1.41
42	Malaria	Enrichment	TNF	1.33
43	Autoinflammatory disease	Enrichment	NLRP3	1.31
44	Systemic lupus erythematosus	Enrichment	TNF	1.11
45	Type 2 diabetes mellitus	Enrichment	IL6	1.08
46	Gastric cancer	Enrichment	IL1B	1.07

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Prostaglandin signaling

Pathway Network for Prostaglandin signaling

Member Pathways for Prostaglandin signaling

Pathways in the Prostaglandin signaling SuperPath

Associated Genes for Prostaglandin signaling

Associated Disorders for Prostaglandin signaling

Disorders associated with Prostaglandin signaling SuperPath

STRING Interaction Network for Prostaglandin signaling

Sources for Prostaglandin signaling