Protein lipoylation

No Pathway Network information available for Protein lipoylation

#	Name	Source	Genes
1	Protein lipoylation	Reactome	DBT DLAT DLST FDX1 GCSH LIAS LIPT1 LIPT2 NDUFAB1 NFU1 (see all 10) (see less)
2	lipoate salvage	PubChem	LIPT1

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	LIPT1	Lipoyltransferase 1	Protein Coding	2
2	LIAS	Lipoic Acid Synthetase	Protein Coding	1
3	DBT	Dihydrolipoamide Branched Chain Transacylase E2	Protein Coding	1
4	DLAT	Dihydrolipoamide S-Acetyltransferase	Protein Coding	1
5	DLST	Dihydrolipoamide S-Succinyltransferase	Protein Coding	1
6	FDX1	Ferredoxin 1	Protein Coding	1
7	GCSH	Glycine Cleavage System Protein H	Protein Coding	1
8	NFU1	NFU1 Iron-Sulfur Cluster Scaffold	Protein Coding	1
9	LIPT2	Lipoyl(Octanoyl) Transferase 2	Protein Coding	1
10	NDUFAB1	NADH:Ubiquinone Oxidoreductase Subunit AB1	Protein Coding	1

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Lipoyltransferase 1 deficiency	Enrichment	LIPT1	3.83
2	Hyperglycinemia, lactic acidosis, and seizures	Enrichment	LIAS	3.13
3	Maple syrup urine disease, type ii	Enrichment	DBT	3.13
4	Spastic paraplegia 93, autosomal recessive	Enrichment	NFU1	3.13
5	Pheochromocytoma/paraganglioma syndrome 7	Enrichment	DLST	3.13
6	Lipoic acid synthetase deficiency	Enrichment	LIAS	3.13
7	Optic nerve disease	Enrichment	LIPT1	3.13
8	Multiple mitochondrial dysfunctions syndrome 1	Enrichment	NFU1	2.83
9	Pyruvate dehydrogenase e2 deficiency	Enrichment	DLAT	2.83
10	Multiple mitochondrial dysfunctions syndrome 7	Enrichment	GCSH	2.83
11	Encephalopathy, neonatal severe, with lactic acidosis and brain abnormalities	Enrichment	LIPT2	2.83
12	Maple syrup urine disease, type ia	Enrichment	DBT	2.66
13	Intermittent maple syrup urine disease	Enrichment	DBT	2.66
14	Classic maple syrup urine disease	Enrichment	DBT	2.66
15	Intermediate maple syrup urine disease	Enrichment	DBT	2.53
16	Atypical glycine encephalopathy	Enrichment	GCSH	2.53
17	Glycine encephalopathy	Enrichment	GCSH	2.35
18	Leigh syndrome, nuclear	Enrichment	LIPT1	2.29
19	Leigh disease	Enrichment	LIPT1	2.25
20	Glycine encephalopathy 1	Enrichment	GCSH	2.23
21	Hereditary paraganglioma-pheochromocytoma syndromes	Enrichment	DLST	1.81

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Pathway Network for Protein lipoylation