protein N-glycosylation processing phase (plants and animals)
Pathway network for the protein N-glycosylation processing phase (plants and animals) SuperPath
Sources:
- PubChem
- Reactome
Pathways in the protein N-glycosylation processing phase (plants and animals) SuperPath
| # | Name | Source | Genes |
|---|---|---|---|
| 1 | protein N-glycosylation processing phase (plants and animals) | PubChem | |
| 2 | protein N-glycosylation processing phase (mammalian) | PubChem | |
| 3 | Defective MAN1B1 causes MRT15 | Reactome |
Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways
| # | Symbol | Description | Category | # Related Pathways |
|---|---|---|---|---|
| 1 | MAN1B1 | Mannosidase Alpha Class 1B Member 1 | Protein Coding | 3 |
| 2 | MAN1C1 | Mannosidase Alpha Class 1C Member 1 | Protein Coding | 2 |
| 3 | MAN1A2 | Mannosidase Alpha Class 1A Member 2 | Protein Coding | 2 |
| 4 | MAN1A1 | Mannosidase Alpha Class 1A Member 1 | Protein Coding | 2 |
| 5 | MANEA | Mannosidase Endo-Alpha | Protein Coding | 2 |
| 6 | PRKCSH | PRKCSH Beta Subunit Of Glucosidase II | Protein Coding | 2 |
| 7 | MOGS | Mannosyl-Oligosaccharide Glucosidase | Protein Coding | 2 |
| 8 | GANAB | Glucosidase II Alpha Subunit | Protein Coding | 2 |
Disorders associated with protein N-glycosylation processing phase (plants and animals) SuperPath
according to GeneCards Suite gene sharing
| # | Disorder | Type | Genes | Score |
|---|---|---|---|---|
| 1 | Non-syndromic x-linked intellectual disability | Direct | ||
| 2 | Polycystic liver disease | Enrichment | GANAB, PRKCSH | 4.39 |
| 3 | Autosomal dominant polycystic liver disease | Enrichment | GANAB, PRKCSH | 4.39 |
| 4 | Man1b1-congenital disorder of glycosylation | Enrichment | MAN1B1 | 3.23 |
| 5 | Congenital disorder of glycosylation, type iib | Enrichment | MOGS | 2.93 |
| 6 | Rafiq syndrome | Enrichment | MAN1B1 | 2.93 |
| 7 | Polycystic kidney disease 3 | Enrichment | GANAB | 2.93 |
| 8 | Polycystic liver disease 1 with or without kidney cysts | Enrichment | PRKCSH | 2.53 |
| 9 | Polycystic kidney disease 3 with or without polycystic liver disease | Enrichment | GANAB | 2.53 |
| 10 | Polycystic liver disease 1 | Enrichment | PRKCSH | 2.53 |
| 11 | Autosomal dominant polycystic kidney disease | Enrichment | GANAB | 2.05 |
| 12 | Autosomal recessive non-syndromic intellectual disability | Enrichment | MAN1B1 | 1.47 |