Protein repair
Pathways in the Protein repair SuperPath
| # | Name | Source | Genes |
|---|---|---|---|
| 1 | Protein repair | Reactome | |
| 2 | Sulindac metabolic pathway | WikiPathways |
Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways
| # | Symbol | Description | Category | # Related Pathways |
|---|---|---|---|---|
| 1 | MSRB2 | Methionine Sulfoxide Reductase B2 | Protein Coding | 2 |
| 2 | MSRB3 | Methionine Sulfoxide Reductase B3 | Protein Coding | 2 |
| 3 | MSRA | Methionine Sulfoxide Reductase A | Protein Coding | 2 |
| 4 | PCMT1 | Protein-L-Isoaspartate (D-Aspartate) O-Methyltransferase | Protein Coding | 1 |
| 5 | MSRB1 | Methionine Sulfoxide Reductase B1 | Protein Coding | 1 |
| 6 | TXN | Thioredoxin | Protein Coding | 1 |
| 7 | CYP1B1 | Cytochrome P450 Family 1 Subfamily B Member 1 | Protein Coding | 1 |
| 8 | CYP1A2 | Cytochrome P450 Family 1 Subfamily A Member 2 | Protein Coding | 1 |
Disorders associated with Protein repair SuperPath
according to GeneCards Suite gene sharing
| # | Disorder | Type | Genes | Score |
|---|---|---|---|---|
| 1 | Deafness, autosomal recessive 74 | Enrichment | MSRB3 | 3.43 |
| 2 | Glaucoma 1, open angle, a | Enrichment | CYP1B1 | 3.13 |
| 3 | Anterior segment dysgenesis 6 | Enrichment | CYP1B1 | 3.13 |
| 4 | Primary congenital glaucoma | Enrichment | CYP1B1 | 3.13 |
| 5 | Glaucoma 3, primary infantile, b | Enrichment | CYP1B1 | 2.83 |
| 6 | Juvenile glaucoma | Enrichment | CYP1B1 | 2.73 |
| 7 | Glaucoma, primary open angle | Enrichment | CYP1B1 | 2.66 |
| 8 | Anterior segment dysgenesis 5 | Enrichment | CYP1B1 | 2.66 |
| 9 | Glaucoma 3, primary congenital, a | Enrichment | CYP1B1 | 2.59 |
| 10 | Peters-plus syndrome | Enrichment | CYP1B1 | 2.43 |
| 11 | Anterior segment dysgenesis | Enrichment | CYP1B1 | 2.26 |
| 12 | Schizophrenia | Enrichment | MSRA | 1.67 |
| 13 | Deafness, autosomal recessive | Enrichment | MSRB3 | 1.64 |
| 14 | Autosomal recessive nonsyndromic deafness | Enrichment | MSRB3 | 1.63 |
| 15 | Rare autosomal recessive non-syndromic sensorineural deafness type dfnb | Enrichment | MSRB3 | 1.49 |