PRPP biosynthesis
Pathways in the PRPP biosynthesis SuperPath
| # | Name | Source | Genes |
|---|---|---|---|
| 1 | PRPP biosynthesis | PubChem | |
| 2 | 5-Phosphoribose 1-diphosphate biosynthesis | Reactome |
Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways
Disorders associated with PRPP biosynthesis SuperPath
according to GeneCards Suite gene sharing
| # | Disorder | Type | Genes | Score |
|---|---|---|---|---|
| 1 | Charcot-marie-tooth disease, x-linked recessive, 5 | Enrichment | PRPS1 | 3.66 |
| 2 | Arts syndrome | Enrichment | PRPS1 | 3.66 |
| 3 | Phosphoribosylpyrophosphate synthetase superactivity | Enrichment | PRPS1 | 3.66 |
| 4 | Deafness, x-linked 1 | Enrichment | PRPS1 | 3.66 |
| 5 | X-linked intellectual disability-limb spasticity-retinal dystrophy-diabetes insipidus syndrome | Enrichment | PRPS1 | 3.66 |
| 6 | Rare x-linked non-syndromic sensorineural deafness type dfn | Enrichment | PRPS1 | 3.05 |
| 7 | Hereditary retinal dystrophy | Enrichment | PRPS1 | 1.20 |
| 8 | Fundus dystrophy | Enrichment | PRPS1 | 1.20 |
