PtdIns(4,5)P2 in cytokinesis pathway

No Pathway Network information available for PtdIns(4,5)P2 in cytokinesis pathway

#	Name	Source	Genes
1	PtdIns(4,5)P2 in cytokinesis pathway	WikiPathways	AFAP1 ANLN EZR KIF23 MSN OCRL RAB35 RACGAP1 RDX RHOA SEPTIN2 (see all 11) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	ANLN	Anillin, Actin Binding Protein	Protein Coding	1
2	AFAP1	Actin Filament Associated Protein 1	Protein Coding	1
3	RDX	Radixin	Protein Coding	1
4	OCRL	OCRL Inositol Polyphosphate-5-Phosphatase	Protein Coding	1
5	MSN	Moesin	Protein Coding	1
6	KIF23	Kinesin Family Member 23	Protein Coding	1
7	RACGAP1	Rac GTPase Activating Protein 1	Protein Coding	1
8	EZR	Ezrin	Protein Coding	1
9	SEPTIN2	Septin 2	Protein Coding	1
10	RAB35	RAB35, Member RAS Oncogene Family	Protein Coding	1
11	RHOA	Ras Homolog Family Member A	Protein Coding	1

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Anemia, congenital dyserythropoietic, type iiia	Enrichment	KIF23, RACGAP1	6.22
2	Immunodeficiency 50	Enrichment	MSN	3.09
3	Deafness, autosomal recessive 24	Enrichment	RDX	3.09
4	Focal segmental glomerulosclerosis 8	Enrichment	ANLN	3.09
5	Lowe oculocerebrorenal syndrome	Enrichment	OCRL	3.09
6	Ectodermal dysplasia with facial dysmorphism and acral, ocular, and brain anomalies	Enrichment	RHOA	3.09
7	Linear hypopigmentation and craniofacial asymmetry with acral, ocular and brain anomalies	Enrichment	RHOA	3.09
8	Congenital dyserythropoietic anemia type iiib	Enrichment	RACGAP1	3.09
9	Anemia, congenital dyserythropoietic, type iiib, autosomal recessive	Enrichment	RACGAP1	3.09
10	Dent disease 2	Enrichment	OCRL	2.79
11	Dent disease	Enrichment	OCRL	2.61
12	Hemihyperplasia, isolated	Enrichment	RHOA	2.31
13	Genetic steroid-resistant nephrotic syndrome	Enrichment	ANLN	1.56
14	Non-syndromic genetic deafness	Enrichment	RDX	1.54
15	Nonsyndromic hearing loss	Enrichment	RDX	1.47
16	Autosomal recessive non-syndromic intellectual disability	Enrichment	EZR	1.34
17	Rare genetic deafness	Enrichment	RDX	1.21
18	Rare autosomal recessive non-syndromic sensorineural deafness type dfnb	Enrichment	RDX	1.16
19	Microcephaly	Enrichment	KIF23	1.02

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Pathway Network for PtdIns(4,5)P2 in cytokinesis pathway