pyrimidine deoxyribonucleotides biosynthesis from CTP

Sources:

#	Name	Source	Genes
1	pyrimidine deoxyribonucleotides biosynthesis from CTP	PubChem	DCTD DTYMK NME1 NME2 NTPCR RRM1 RRM2 TYMS (see all 8) (see less)
2	pyrimidine deoxyribonucleotides de novo biosynthesis	PubChem	DTYMK DUT NME1 NME2 NME3 NME4 NME5 NME6 NME7 NTPCR RRM1 RRM2 RRM2B TYMS (see all 14) (see less)
3	guanosine deoxyribonucleotides de novo biosynthesis	PubChem	NME1 NME2 NME3 NME4 NME5 NME6 NME7 RRM1 RRM2 RRM2B (see all 10) (see less)
4	adenosine deoxyribonucleotides de novo biosynthesis	PubChem	NME1 NME2 RRM1 RRM2
5	guanosine deoxyribonucleotides de novo biosynthesis I	PubChem	NME1 NME2 RRM1 RRM2

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	NME1	NME/NM23 Nucleoside Diphosphate Kinase 1	Protein Coding	5
2	NME2	NME/NM23 Nucleoside Diphosphate Kinase 2	Protein Coding	5
3	RRM1	Ribonucleotide Reductase Catalytic Subunit M1	Protein Coding	5
4	RRM2	Ribonucleotide Reductase Regulatory Subunit M2	Protein Coding	5
5	NTPCR	Nucleoside-Triphosphatase, Cancer-Related	Protein Coding	2
6	DTYMK	Deoxythymidylate Kinase	Protein Coding	2
7	TYMS	Thymidylate Synthetase	Protein Coding	2
8	NME5	NME/NM23 Family Member 5	Protein Coding	2
9	NME3	NME/NM23 Nucleoside Diphosphate Kinase 3	Protein Coding	2
10	NME6	NME/NM23 Nucleoside Diphosphate Kinase 6	Protein Coding	2
11	NME7	NME/NM23 Family Member 7	Protein Coding	2
12	RRM2B	Ribonucleotide Reductase Regulatory TP53 Inducible Subunit M2B	Protein Coding	2
13	NME4	NME/NM23 Nucleoside Diphosphate Kinase 4	Protein Coding	2
14	DCTD	DCMP Deaminase	Protein Coding	1
15	DUT	Deoxyuridine Triphosphatase	Protein Coding	1

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Progressive external ophthalmoplegia with mitochondrial dna deletions, autosomal recessive 6	Enrichment	RRM1	3.53
2	Neurodegeneration, childhood-onset, with progressive microcephaly	Enrichment	DTYMK	3.23
3	Mitochondrial dna depletion syndrome 8b	Enrichment	RRM2B	3.13
4	Ciliary dyskinesia, primary, 48, without situs inversus	Enrichment	NME5	3.13
5	Rrm2b mitochondrial dna maintenance defects	Enrichment	RRM2B	3.13
6	Bone marrow failure and diabetes mellitus syndrome	Enrichment	DUT	2.99
7	Dyskeratosis congenita, digenic	Enrichment	TYMS	2.93
8	Fanconi renotubular syndrome 1	Enrichment	RRM2B	2.83
9	Rod-cone dystrophy, sensorineural deafness, and fanconi-type renal dysfunction	Enrichment	RRM2B	2.83
10	Progressive external ophthalmoplegia with mitochondrial dna deletions, autosomal dominant 5	Enrichment	RRM2B	2.83
11	Mitochondrial dna depletion syndrome 8a	Enrichment	RRM2B	2.83
12	Progressive external ophthalmoplegia with mitochondrial dna deletions, autosomal recessive 2	Enrichment	RRM2B	2.83
13	Idiopathic camptocormia	Enrichment	RRM2B	2.66
14	Kearns-sayre syndrome	Enrichment	RRM2B	2.43
15	Progressive external ophthalmoplegia with mitochondrial dna deletions, autosomal dominant 1	Enrichment	RRM2B	2.35
16	Mitochondrial neurogastrointestinal encephalomyopathy	Enrichment	RRM2B	2.18
17	Dyskeratosis congenita	Enrichment	TYMS	1.95
18	Visceral heterotaxy 5	Enrichment	NME7	1.65
19	Sensorineural hearing loss	Enrichment	RRM2B	1.46
20	Primary ciliary dyskinesia	Enrichment	NME5	1.26
21	Mitochondrial disease	Enrichment	RRM2B	1.21
22	Retinitis pigmentosa	Enrichment	RRM2B	0.84

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Pathway Network for pyrimidine deoxyribonucleotides biosynthesis from CTP