Ramipril Pathway, Pharmacokinetics
Pathways in the Ramipril Pathway, Pharmacokinetics SuperPath
| # | Name | Source | Genes |
|---|---|---|---|
| 1 | Ramipril Pathway, Pharmacokinetics | PharmGKB |
Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways
| # | Symbol | Description | Category | # Related Pathways |
|---|---|---|---|---|
| 1 | UGT1A1 | UDP Glucuronosyltransferase Family 1 Member A1 | Protein Coding | 1 |
| 2 | ACE | Angiotensin I Converting Enzyme | Protein Coding | 1 |
| 3 | ABCG2 | ATP Binding Cassette Subfamily G Member 2 (JR Blood Group) | Protein Coding | 1 |
| 4 | SLCO1B1 | Solute Carrier Organic Anion Transporter Family Member 1B1 | Protein Coding | 1 |
Disorders associated with Ramipril Pathway, Pharmacokinetics SuperPath
according to GeneCards Suite gene sharing
| # | Disorder | Type | Genes | Score |
|---|---|---|---|---|
| 1 | Gilbert syndrome | Enrichment | SLCO1B1, UGT1A1 | 5.45 |
| 2 | Uric acid concentration, serum, quantitative trait locus 1 | Enrichment | ABCG2 | 3.53 |
| 3 | Microvascular complications of diabetes 3 | Enrichment | ACE | 3.53 |
| 4 | Blood group, junior system | Enrichment | ABCG2 | 3.53 |
| 5 | Hyperbilirubinemia, rotor type | Enrichment | SLCO1B1 | 3.05 |
| 6 | Renal tubular dysgenesis | Enrichment | ACE | 2.75 |
| 7 | Hemorrhage, intracerebral | Enrichment | ACE | 2.75 |
| 8 | Crigler-najjar syndrome, type i | Enrichment | UGT1A1 | 2.53 |
| 9 | Hyperbilirubinemia, transient familial neonatal | Enrichment | UGT1A1 | 2.53 |
| 10 | Stroke, ischemic | Enrichment | ACE | 2.53 |
| 11 | Bilirubin, serum level of, quantitative trait locus 1 | Enrichment | UGT1A1 | 2.53 |
| 12 | Crigler-najjar syndrome, type ii | Enrichment | UGT1A1 | 2.53 |
| 13 | Bilirubin metabolic disorder | Enrichment | UGT1A1 | 2.49 |
| 14 | Myocardial infarction | Enrichment | ACE | 2.19 |
| 15 | Cakut | Enrichment | ACE | 2.00 |
