Ran Pathway

No Pathway Network information available for Ran Pathway

#	Name	Source	Genes
1	Ran Pathway	QIAGEN	IPO5 KPNA1 KPNA2 KPNA3 KPNA4 KPNB1 RAN RANBP1 RANBP2 RANGAP1 RCC1 TNPO1 XPO1 XPO4 XPOT (see all 15) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	RCC1	Regulator Of Chromosome Condensation 1	Protein Coding	1
2	KPNA1	Karyopherin Subunit Alpha 1	Protein Coding	1
3	KPNA2	Karyopherin Subunit Alpha 2	Protein Coding	1
4	KPNA3	Karyopherin Subunit Alpha 3	Protein Coding	1
5	KPNA4	Karyopherin Subunit Alpha 4	Protein Coding	1
6	KPNB1	Karyopherin Subunit Beta 1	Protein Coding	1
7	IPO5	Importin 5	Protein Coding	1
8	RAN	RAN, Member RAS Oncogene Family	Protein Coding	1
9	RANBP1	RAN Binding Protein 1	Protein Coding	1
10	RANBP2	RAN Binding Protein 2	Protein Coding	1
11	RANGAP1	Ran GTPase Activating Protein 1	Protein Coding	1
12	TNPO1	Transportin 1	Protein Coding	1
13	XPO1	Exportin 1	Protein Coding	1
14	XPO4	Exportin 4	Protein Coding	1
15	XPOT	Exportin For TRNA	Protein Coding	1

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Spastic paraplegia 88, autosomal dominant	Enrichment	KPNA3	2.96
2	Infection-induced acute-onset axonal neuropathy	Enrichment	RCC1	2.96
3	Familial acute necrotizing encephalopathy	Enrichment	RANBP2	2.96
4	Nephronophthisis-like nephropathy 1	Enrichment	RANGAP1	2.66
5	Spastic paraplegia 37, autosomal dominant	Enrichment	KPNA3	2.66
6	Primary mediastinal large b-cell lymphoma	Enrichment	XPO1	2.66
7	Acute necrotizing encephalopathy of childhood	Enrichment	RANBP2	2.66
8	Ectodermal dysplasia 11b, hypohidrotic/hair/tooth type, autosomal recessive	Enrichment	RANBP2	2.48
9	Ectodermal dysplasia 10b, hypohidrotic/hair/tooth type, autosomal recessive	Enrichment	RANBP2	2.35
10	Ectodermal dysplasia	Enrichment	RANBP2	2.35
11	Ectodermal dysplasia 10a, hypohidrotic/hair/nail type, autosomal dominant	Enrichment	RANBP2	2.26
12	Autosomal recessive hypohidrotic ectodermal dysplasia syndrome	Enrichment	RANBP2	2.26
13	Inflammatory myofibroblastic tumor	Enrichment	RANBP2	2.18
14	Mitochondrial dna depletion syndrome 4a	Enrichment	RANBP2	2.11
15	Mitochondrial dna depletion syndrome 4b	Enrichment	RANBP2	2.05
16	Tooth agenesis	Enrichment	RANBP2	1.62

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Pathway Network for Ran Pathway